- Conditions: Traumatic Brain Injury; Substance Abuse; Substance Dependence
Interventions: Drug: Citicoline; Drug: Omega-3; Other: Rice bran oil; Other: Microcrystalline Cellulose
Sponsor: Deborah Yurgelun-Todd
Not yet recruiting - verified January 2012 - Conditions: Schizophrenia; Schizoaffective Disorder
Interventions: Drug: DAR-100A; Drug: Placebo
Sponsor: New York State Psychiatric Institute
Recruiting - verified January 2012 - Condition: Nicotine Dependence
Intervention:
Sponsor: National Institute on Drug Abuse (NIDA)
Recruiting - verified November 2011 - Condition: Cannabis-use Disorders
Intervention: Drug: Tiagabine
Sponsor: University of Kentucky
Recruiting - verified January 2012 - Condition: Nicotine Dependence
Intervention: Drug: Varenicline or placebo
Sponsors: University of Pennsylvania; National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)
Recruiting - verified January 2012 - Condition: Nicotine Dependence
Intervention:
Sponsor: National Institute on Drug Abuse (NIDA)
Recruiting - verified October 2011 - Conditions: Alcoholism,; Alcoholic Liver Disease
Interventions: Drug: Metadoxine; Drug: Placebo
Sponsors: Brown University; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Not yet recruiting - verified January 2012 - Conditions: Chronic Pain; Opioid Abuse, Unspecified Use
Interventions: Behavioral: Mindfulness-Oriented Recovery Enhancement; Behavioral: Conventional Support Group (SG)
Sponsors: Florida State University; National Institute on Drug Abuse (NIDA); Fahs Beck Fund for Research and Experimentation
Recruiting - verified January 2012 - Condition: Chronic Pain
Intervention: Behavioral: Therapeutic Education System (TES) for chronic pain
Sponsors: National Development and Research Institutes, Inc.; National Institute on Drug Abuse (NIDA); Beth Israel Medical Center
Not yet recruiting - verified December 2011 - Condition: Addiction
Interventions: Drug: Atomoxetine; Drug: Sugar Pill
Sponsor: Yale University
Recruiting - verified December 2011 - Condition: Cocaine Use Disorders
Interventions: Drug: High-dose donepezil; Drug: Low-dose donepezil; Drug: Selegiline; Drug: Placebo
Sponsors: Midwest Biomedical Research Foundation; National Institute on Drug Abuse (NIDA)
Not yet recruiting - verified December 2011 - Conditions: Drug Abuse; Healthy
Interventions: Drug: TC-5214; Drug: TC-5214 Placebo; Drug: Ketamine; Drug: Phentermine; Drug: TC-5214; Drug: TC-5214; Drug: Phentermine
Sponsor: AstraZeneca
Not yet recruiting - verified December 2011 - Condition: Nicotine Addiction
Interventions: Drug: Saline; Drug: Nicotine
Sponsor: Yale University
Recruiting - verified December 2011 - Conditions: Alcohol Abuse; Alcohol Dependence; Drug Abuse; Drug Dependence
Intervention: Behavioral: Integrated Twelve-Step Facilitation
Sponsor: Massachusetts General Hospital
Recruiting - verified October 2011 - Conditions: Adolescents; Conduct Disorder; Vulnerability to Substance Addicition
Intervention:
Sponsor: National Institute on Drug Abuse (NIDA)
Recruiting - verified July 2011 - Condition: Schizophrenia
Interventions: Drug: Nicotine polacrilex; Drug: Regular chewing gum; Dentyne Ice, Wrigely´s Mint Gum
Sponsor: Centre for Addiction and Mental Health
Recruiting - verified January 2012 - Condition: Healthy
Interventions: Drug: Placebo; Drug: Vorikonazole
Sponsor: Turku University Hospital
Recruiting - verified November 2011 - Condition: Substance-Related Disorders
Interventions: Behavioral: Substance Abuse Education; Behavioral: Mind-body Bridging
Sponsor: University of Utah
Recruiting - verified September 2011 - Condition: Treatment-Resistant Depression Disease
Interventions: Other: Repetitive Transcranial Magnetic Stimulation; Other: Sham rTMS
Sponsor: Tehran University of Medical Sciences
Not yet recruiting - verified November 2011 - Conditions: Stress Disorders, Post-Traumatic; Substance-Related Disorders
Interventions: Behavioral: Cognitive Behavioral Therapy for PTSD; Behavioral: Individual Addiction Counseling; Behavioral: Treatment as usual
Sponsors: Dartmouth-Hitchcock Medical Center; National Institute on Drug Abuse (NIDA)
Recruiting - verified October 2011 - Condition: Smoking
Intervention: Behavioral: Behavior smoking cessation counseling with nicotine patch
Sponsors: Brown University; National Cancer Institute (NCI)
Recruiting - verified October 2011 - Conditions: Stress Disorder, Post-Traumatic; Substance-Related Disorders
Interventions: Behavioral: Integrated Cognitive Behavioral Therapy; Behavioral: Treatment-as-usual
Sponsors: Dartmouth-Hitchcock Medical Center; Brown University; Providence VA Medical Center; National Institute on Drug Abuse (NIDA)
Recruiting - verified October 2011 - Condition: Healthy Volunteer
Interventions: Drug: RO4917838; Drug: diazepam; Drug: Placebo
Sponsor: Hoffmann-La Roche
Recruiting - verified January 2012 - Conditions: Smoking; Addiction
Intervention: Drug: Nicabate 21mg Transdermal Nicotine Replacement Therapy (NRT)Patch
Sponsors: The Queen Elizabeth Hospital; Basil Hetzel Institute for Translational Research; University of Adelaide; University of South Australia; Clinical Practice Unit; Therapeutics Research Centre
Recruiting - verified September 2011 - Conditions: Substance Abuse; Substance Dependence; Cognitive Impairment
Interventions: Behavioral: Cognitive Training + Work Therapy; Behavioral: Work Therapy
Sponsor: Yale University
Recruiting - verified August 2011 - Conditions: Alcohol Dependence; Anxiety
Interventions: Drug: Doxazosin; Drug: Placebo
Sponsors: Brown University; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified September 2011 - Conditions: Addictions; Adolescents; Primary Health Care; Brief Intervention
Intervention: Behavioral: Brief Intervention
Sponsor: University Hospital, Clermont-Ferrand
Not yet recruiting - verified September 2011 - Condition: Addiction
Intervention: Behavioral: STICA Intervention
Sponsor: Johannes Gutenberg University Mainz
Recruiting - verified January 2012 - Conditions: Obesity; Phentermine Withdrawal
Intervention: Drug: Abrupt cessation of phentermine pharmacotherapy
Sponsors: Center for Weight Management, California; American Society of Bariatric Physicians
Recruiting - verified August 2011 - Condition: Schizophrenia
Interventions: Drug: Lurasidone; Drug: Matching Placebo
Sponsor: Sunovion
Recruiting - verified January 2012 - Condition: Smoking
Interventions: Drug: Nicotine replacement therapy; Other: No intervention
Sponsors: Centre for Addiction and Mental Health; Canadian Institutes of Health Research (CIHR)
Not yet recruiting - verified September 2011 - Conditions: Infection; Hypertension; Anesthesia; Pain; Reflux
Intervention:
Sponsors: Duke University; Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); The EMMES Corporation
Recruiting - verified January 2012 - Condition: Opioid Dependence
Intervention:
Sponsor: Alkermes
Recruiting - verified December 2011 - Conditions: Dosimetry; Pharmacokinetics
Intervention: Drug: [11C]LY2428703
Sponsor: National Institute of Mental Health (NIMH)
Recruiting - verified January 2012 - Conditions: HIV; Drug Addiction
Interventions: Behavioral: Psycho-education; Behavioral: Experimental
Sponsors: RTI International; University of Cape Town
Recruiting - verified December 2011 - Conditions: Nicotine Dependence; Opiate Dependence
Interventions: Behavioral: Intensive, tailored intervention; Behavioral: NJ Quitline Referral
Sponsors: University of Medicine and Dentistry New Jersey; National Institute on Drug Abuse (NIDA)
Recruiting - verified January 2012 - Conditions: Alcoholism; Substance-Related Disorders; Smoking; Chronic Disease; Malnutrition
Intervention: Behavioral: Health promotion activities
Sponsors: Skane University Hospital; Swedish Council for Working Life and Social Research; The Swedish Council for Information on Alcohol and Other Drugs; Lund University; Copenhagen University Hospital, Denmark
Recruiting - verified October 2011 - Condition: Cocaine Dependence
Interventions: Drug: Buprenorphine + Naltrexone; Drug: Placebo + Naltrexone
Sponsors: Walter Ling; National Institute on Drug Abuse (NIDA); The EMMES Corporation
Recruiting - verified January 2012 - Conditions: Impulsive Behavior; Substance Abuse; HIV Risk Behavior; Anxiety; Depression; Criminogenic Thinking
Interventions: Behavioral: REVAMP; Behavioral: TAU
Sponsor: George Mason University
Recruiting - verified June 2011 - Condition: Cocaine Dependence
Interventions: Drug: Oral tacrine; Drug: Oral placebo
Sponsor: Midwest Biomedical Research Foundation
Not yet recruiting - verified July 2011 - Conditions: Alcoholism; Genetics
Intervention: Drug: Ethanol
Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified May 2011 - Conditions: Domestic Violence; Substance Abuse; Parenting
Interventions: Behavioral: Fathers for Change; Behavioral: Individual Drug Counseling
Sponsors: Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified June 2011 - Conditions: Stress Disorders, Post-Traumatic; Substance-Related Disorders
Interventions: Behavioral: Concurrent Treatment of PTSD and Substance Dependence; Behavioral: Relapse Prevention Treatment
Sponsors: The City College of New York; National Institute on Drug Abuse (NIDA)
Recruiting - verified June 2011 - Conditions: Substance Related Disorders; Drug Addiction; Substance Abuse
Interventions: Behavioral: Cash CM; Behavioral: Voucher CM; Behavioral: Non-CM Control
Sponsors: Treatment Research Institute; National Institute on Drug Abuse (NIDA)
Recruiting - verified July 2011 - Condition: Smoking Cessation
Interventions: Drug: D-cycloserine; Drug: Placebo
Sponsor: Massachusetts General Hospital
Recruiting - verified July 2011 - Condition: Alcoholism
Interventions: Behavioral: SMART Recovery face-to-face meetings; Behavioral: Overcoming Addictions web application
Sponsors: Behavior Therapy Associates, LLP; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified September 2011 - Conditions: Cocaine Abuse or Dependence; Cocaine Related Disorders
Intervention:
Sponsor: Wayne State University
Recruiting - verified October 2011 - Conditions: HIV Risk Behaviors; Heroin Injection; Retention in Methadone Treatment
Interventions: Behavioral: Behavioral Drug and Risk Counseling (BDRC); Behavioral: methadone maintenance treatment
Sponsors: University of Pennsylvania; National Institute on Drug Abuse (NIDA)
Recruiting - verified May 2011 - Condition: Metastatic Breast Cancer
Intervention: Other: Biopsy
Sponsors: Federation Nationale des Centres de Lutte Contre le Cancer; Ministry of Health, France; Institut Gustave Roussy
Recruiting - verified August 2011 - Condition: Tobacco Dependence
Interventions: Behavioral: Innovative System; Behavioral: Standard Treatment Control (STC)
Sponsors: University of California, San Francisco; National Institute on Drug Abuse (NIDA)
Recruiting - verified May 2011 - Condition: Nicotine Dependence
Interventions: Drug: Varenicline; Drug: Bupropion; Drug: Nicotine patches
Sponsors: Duke University; National Institute on Drug Abuse (NIDA)
Recruiting - verified January 2012 - Conditions: Substance-Related Disorders; Drug Addiction; Substance Abuse
Interventions: Behavioral: Community Reinforcement and Family Training; Behavioral: Al-Anon Facilitation
Sponsors: Treatment Research Institute; Robert J. Meyers PhD & Associates
Recruiting - verified December 2011 - Conditions: Attention Deficit Hyperactivity Disorder; Attention Deficit Disorder
Intervention: Behavioral: MIP Protocol
Sponsors: The National Center on Addiction and Substance Abuse at Columbia University; National Institute on Drug Abuse (NIDA)
Not yet recruiting - verified June 2011 - Condition: Pain
Interventions: Behavioral: Psychoeducation for substance abuse; Behavioral: CBT for pain in Substance abuse
Sponsors: University of Michigan; National Institute on Drug Abuse (NIDA)
Not yet recruiting - verified June 2011 - Conditions: Cigarette Smoking; Drug Use
Interventions: Behavioral: Standard Treatment; Behavioral: BAD-AS; Drug: Transdermal Nicotine Patch
Sponsors: University of Maryland; American Cancer Society
Recruiting - verified July 2011 - Conditions: Chronic Pain; Opioid Dependence
Interventions: Drug: Varenicline; Drug: Placebo
Sponsor: Mayo Clinic
Recruiting - verified September 2011 - Conditions: Posttraumatic Stress Disorders; Combat Disorders; Alcohol Dependence; Drug Dependence
Intervention: Behavioral: Concurrent Treatment with Prolonged Exposure (COPE)
Sponsor: Medical University of South Carolina
Not yet recruiting - verified April 2011 - Conditions: Major Depressive Disorder, Recurrent, Unspecified; Major Depressive Disorder, Single Episode, Unspecified
Intervention: Other: H-Coil Deep TMS in combination with SSRIs
Sponsor: Brainsway
Not yet recruiting - verified May 2011 - Condition: Opiate Dependence
Interventions: Behavioral: Behavioral Drug and HIV Risk Reduction Counseling; Behavioral: Educational Counseling; Behavioral: Treatment as Usual
Sponsors: Yale University; Centers for Disease Control and Prevention, China
Recruiting - verified July 2011 - Condition: Methamphetamine Dependence
Intervention: Drug: Modafinil
Sponsor: California Pacific Medical Center Research Institute
Not yet recruiting - verified May 2011 - Condition: Healthy Smokers
Intervention: Behavioral: Mindfulness behavioral intervention (MT),cognitive behavioral intervention (CBT)
Sponsor: Massachusetts General Hospital
Recruiting - verified May 2011 - Conditions: Alcohol-induced Cue-craving; Alcohol Sensitivity
Interventions: Drug: Placebo Comparator; Drug: Active Comparator: Atomoxetine, Placebo
Sponsors: University of Virginia; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified April 2011 - Conditions: Alcohol Consumption; Unsafe Sex
Interventions: Behavioral: Brief Motivational Intervention (BMI); Behavioral: Brief Advice
Sponsors: Brown University; National Institute on Alcohol Abuse and Alcoholism (NIAAA); Memorial Hospital of Rhode Island; Kent Hospital
Recruiting - verified November 2011 - Condition: Substance Use Disorders
Interventions: Behavioral: Drum-Assisted Recovery Therapy for Native Americans (DARTNA); Behavioral: Treatment-As-Usual
Sponsor: University of California, Los Angeles
Recruiting - verified April 2011 - Conditions: Cocaine Addiction; Cocaine-related Disorder; Executive Dysfunction
Intervention: Device: transcranial Direct Current Stimulation
Sponsors: Federal University of Espirito Santo; Harvard University; University of Göttingen
Recruiting - verified March 2011 - Conditions: Substance Abuse; Substance Dependence; Alcohol Abuse; Drug Use; Relapse
Interventions: Behavioral: Dual Processing; Behavioral: Relapse Prevention
Sponsors: Inova Health Care Services; Virginia Commonwealth University; Georgetown University
Recruiting - verified August 2011 - Condition: Drug Addiction
Intervention: Drug: Varenicline
Sponsor: National Institute on Drug Abuse (NIDA)
Not yet recruiting - verified December 2011 - Conditions: Chronic Pain; Opiate Dependence
Interventions: Behavioral: Cognitive-Behavioral Therapy for Pain and Opioid Dependence; Behavioral: Methadone Drug Counseling
Sponsors: Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified December 2011 - Conditions: HIV; Medication Adherence; Substance Dependence
Intervention: Behavioral: Spiritual Self-Schema Therapy
Sponsors: Hunter College; Fordham University
Recruiting - verified February 2011 - Conditions: Alcoholism; Cocaine Dependence
Interventions: Drug: Vigabatrin; Drug: Placebo
Sponsor: University of Pennsylvania
Recruiting - verified August 2011 - Conditions: Tobacco Smoking; Nicotine Dependence; Impulsivity; Addiction; Substance Dependence
Interventions: Behavioral: Mindfulness Training; Behavioral: Cognitive-Behavioral Therapy
Sponsors: Massachusetts General Hospital; National Institute on Drug Abuse (NIDA); Mind and Life Institute
Recruiting - verified April 2011 - Conditions: Alcohol Dependence; Executive Dysfunction; Abnormal Craving for Drugs
Intervention: Device: transcranial Direct Current Stimulation
Sponsors: Federal University of Espirito Santo; Harvard University; University of Göttingen
Recruiting - verified October 2010 - Condition: Cocaine Addiction
Intervention: Drug: Inderal
Sponsor: McGill University Health Center
Not yet recruiting - verified January 2011 - Condition: Smoking
Interventions: Other: Brief computerized feedback; Other: Resources only (control)
Sponsor: Virginia Commonwealth University
Recruiting - verified October 2011 - Condition: Pain
Interventions: Drug: Celecoxib; Drug: Sugar Pill
Sponsor: Weill Medical College of Cornell University
Recruiting - verified March 2011 - Condition: Nicotine Addiction
Interventions: Drug: Varenicline; Drug: Placebo; Drug: Transdermal Nicotine
Sponsors: University of Pennsylvania; National Institute on Drug Abuse (NIDA)
Recruiting - verified January 2012 - Condition: Opiate Addiction
Interventions: Drug: Cannabidiol; Drug: Fentanyl
Sponsor: Hurd,Yasmin, Ph.D.
Recruiting - verified March 2011 - Conditions: Psychosis; Substance Abuse
Interventions: Behavioral: Skills trainig for patients with dual diagnosis; Behavioral: regular treatment
Sponsor: University of Cologne
Recruiting - verified February 2011 - Condition: Nicotine Dependence
Interventions: Drug: Varenicline (Chantix); Drug: Bupropion (Zyban); Drug: Nicotine patches; Drug: Nicotine Inhaler
Sponsors: Duke University; National Institute on Drug Abuse (NIDA); Philip Morris Products S.A.
Recruiting - verified January 2012 - Condition: Human Immunodeficiency Virus
Interventions: Behavioral: RBT; Other: Case-Management
Sponsors: RTI International; National Institute on Drug Abuse (NIDA)
Recruiting - verified December 2011 - Condition: Tobacco Use Disorder
Intervention:
Sponsors: Centre for Addiction and Mental Health; Pfizer
Recruiting - verified September 2011 - Condition: Nicotine Dependence
Interventions: Behavioral: Integrated Training for Smokers; Behavioral: Mindfulness Training for Smokers
Sponsors: University of Wisconsin, Madison; National Institute on Drug Abuse (NIDA)
Not yet recruiting - verified February 2011 - Conditions: Alcohol Dependence; Alcohol Abuse
Interventions: Drug: Naltrexone; Behavioral: Brenda Therapy Sessions
Sponsors: University of North Carolina, Chapel Hill; National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Institutes of Health (NIH)
Recruiting - verified January 2012 - Conditions: Smoking Cessation; Alcohol Abuse
Interventions: Drug: varenicline; Drug: placebo
Sponsors: Centre for Addiction and Mental Health; Ontario Lung Association
Recruiting - verified August 2011 - Condition: Pathological Gambling
Interventions: Behavioral: CRAFT treatment; Behavioral: Treatment as Usual
Sponsors: Colchester East Hants Health Authority; Pictou County Health Authority; University of Calgary; Dalhousie University
Not yet recruiting - verified April 2011 - Conditions: Cocaine Addiction; Cocaine Dependence
Intervention: Drug: Vigabatrin
Sponsors: Catalyst Pharmaceutical Partners, Inc; National Institute on Drug Abuse (NIDA); Department of Veterans Affairs
Recruiting - verified January 2012 - Condition: Tobacco Use Disorder
Interventions: Drug: Varenicline; Drug: Placebo pill
Sponsors: University of Medicine and Dentistry New Jersey; Pfizer
Recruiting - verified March 2011 - Condition: Bipolar
Interventions: Drug: Lurasidone; Drug: Placebo
Sponsor: Sunovion
Recruiting - verified January 2012 - Condition: Addiction
Interventions: Procedure: Deep brain stimulation; Other: methadone maintenance treatment
Sponsor: Tang-Du Hospital
Recruiting - verified May 2011 - Conditions: Cocaine Dependence; Crack Dependence
Interventions: Drug: Biperiden; Drug: Placebo
Sponsors: Federal University of São Paulo; Nacional Conseling of Scientific Development and Technology, Brazil; Association for Psychopharmacological Research, Brazil
Recruiting - verified June 2011 - Conditions: HIV; AIDS; Opioid Dependence; Drug Dependence
Intervention: Drug: Depot Naltrexone
Sponsors: Yale University; Baystate Medical Center
Recruiting - verified August 2011 - Condition: Substance Use Disorders
Intervention: Behavioral: Computerized cognitively stimulating activities
Sponsors: Johns Hopkins University; National Institute on Drug Abuse (NIDA)
Recruiting - verified June 2011 - Effects of Gabapentin Versus Placebo on Buprenorphine Detoxification of Opioid-dependent IndividualsCondition: Opioid Dependent Individuals Seeking Treatment
Intervention: Drug: Buprenorphine
Sponsors: University of Arkansas; National Institute on Drug Abuse (NIDA)
Recruiting - verified September 2011 - Conditions: Tobacco Use Disorder; Smoking Relapse; Cognitive Training; Nicotine Addiction
Interventions: Behavioral: Cognitive Remediation Training (CRT); Behavioral: Standard Care (SC)
Sponsor: University of Pennsylvania
Recruiting - verified January 2012 - Conditions: PTSD; Substance Addiction
Interventions: Behavioral: Prolonged Exposure; Behavioral: Motivational Enhancement Therapy
Sponsor: Department of Veterans Affairs
Recruiting - verified September 2011 - Conditions: Opioid-Related Disorders; Heroin Dependence
Intervention: Behavioral: Recovery Line Support System
Sponsors: Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified March 2011 - Condition: Nicotine Dependence
Interventions: Drug: Baclofen 30 mg/day; Drug: placebo pill; Drug: Baclofen 60 mg/day
Sponsors: Centre for Addiction and Mental Health; Canadian Tobacco Control Research Initiative
Recruiting - verified December 2011 - Conditions: Alcohol-Related Disorders; Alcohol Dependence; Alcoholism; Anxiety Disorder
Interventions: Drug: Pexacerfont; Drug: Placebo
Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified August 2011 - Condition: Cocaine Use
Intervention: Device: Repetitive Transcranial Magnetic Stimulation
Sponsors: National Institute on Drug Abuse (NIDA); University of Maryland
Not yet recruiting - verified August 2011 - Condition: Healthy Young and Elderly Volunteers
Interventions: Drug: Intravenous Citalopram; Drug: Normal Saline
Sponsors: Rotman Research Institute at Baycrest; Centre for Addiction and Mental Health; University of Toronto
Recruiting - verified January 2012 - Condition: Methamphetamine Dependence
Interventions: Drug: Dextroamphetamine; Drug: Placebo
Sponsor: University of Arkansas
Recruiting - verified October 2011 - Condition: Drug Abuse
Interventions: Behavioral: screening; Behavioral: assessment; Behavioral: referral; Behavioral: Brief intervention; Behavioral: booster sessions
Sponsors: University of New Mexico; National Institute on Drug Abuse (NIDA)
Recruiting - verified August 2011 - Conditions: Nicotine Withdrawal; Marijuana Dependence; Cannabis Dependence; Nicotine Dependence; Cannabis Abuse
Interventions: Drug: Placebo Aprepitant; Drug: Active Aprepitant
Sponsors: University of Virginia; National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2011 - Condition: Smoking Addiction
Interventions: Drug: Placebo; Drug: Varenicline
Sponsors: The Mind Research Network; National Institute on Drug Abuse (NIDA)
Recruiting - verified November 2011 - Conditions: Substance Use Disorders; Posttraumatic Stress Disorder
Interventions: Behavioral: Prolonged Exposure Therapy; Behavioral: Prolonged Exposure therapy + VR/ER
Sponsors: Duke University; Department of Defense; Telemedicine and Advanced Technology Research Center
Recruiting - verified January 2012 - Condition: Alcohol Dependence
Interventions: Drug: GSK561679; Drug: Placebo
Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified November 2011 - Conditions: Pain; Opiate Addiction
Intervention:
Sponsor: Intermountain Health Care, Inc.
Recruiting - verified October 2011 - Condition: Alcoholism
Interventions: Drug: Ghrelin; Drug: Ghrelin; Drug: Saline solution
Sponsor: Brown University
Recruiting - verified August 2010 - Conditions: Substance Abuse; Substance Dependence
Intervention: Behavioral: Behavioral Intervention
Sponsors: Feinstein Institute for Medical Research; National Institute of Mental Health (NIMH)
Not yet recruiting - verified June 2010 - Condition: Smoking Cessation
Intervention: Other: Respiragene test
Sponsors: University of Surrey; Lab 21, Cambridge; NHS Research and Development
Recruiting - verified January 2012 - Conditions: Exercise; Addictive Behaviors
Intervention: Behavioral: VIP CM
Sponsors: University of Connecticut Health Center; National Institute on Drug Abuse (NIDA)
Recruiting - verified November 2011 - Condition: Anorexia Nervosa
Interventions: Drug: Olanzapine; Drug: Placebo
Sponsors: National Institute of Mental Health (NIMH); Weill Medical College of Cornell University; University of Pittsburgh; Johns Hopkins University; University of Toronto
Recruiting - verified November 2011 - Conditions: Drug Addiction; Nicotine Dependence
Intervention: Drug: Nicotrol
Sponsor: National Institute on Drug Abuse (NIDA)
Recruiting - verified September 2011 - Condition: Cocaine Dependence
Interventions: Drug: Zonisamide; Drug: Placebo; Drug: Cocaine Hydrochloride; Behavioral: Neurocognitive and Performance Battery; Behavioral: Smoking Assessments
Sponsors: Johns Hopkins University; National Institute on Drug Abuse (NIDA)
Recruiting - verified June 2011 - Condition: Alcohol Dependence
Interventions: Drug: Quetiapine XR plus mirtazapine; Drug: Quetiapine fumarate extended release (Quetiapine XR)
Sponsor: Dartmouth-Hitchcock Medical Center
Recruiting - verified June 2011 - Condition: Smoking Cessation
Interventions: Behavioral: affect regulation training; Behavioral: health and lifestyle
Sponsors: State University of New York at Buffalo; National Institute on Drug Abuse (NIDA)
Recruiting - verified March 2011 - Condition: Regressors
Intervention:
Sponsor: National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2011 - Condition: Substance Abuse Disorder
Interventions: Behavioral: Low intensity care; Behavioral: Voucher reinforcement
Sponsors: Johns Hopkins University; National Institute on Drug Abuse (NIDA)
Recruiting - verified August 2011 - Condition: Substance Abuse Disorder
Intervention: Behavioral: eGet
Sponsors: Johns Hopkins University; National Institute on Drug Abuse (NIDA)
Recruiting - verified June 2011 - Condition: Substance Use Disorders
Interventions: Behavioral: Voucher Reinforcement; Behavioral: Standard Control
Sponsors: Johns Hopkins University; National Institute on Drug Abuse (NIDA)
Recruiting - verified August 2011 - Condition: Alcoholism
Intervention: Drug: Ondansetron and Sertraline
Sponsors: Brown University; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified June 2011 - Conditions: Cannabis Abuse; Cannabis Dependence
Interventions: Drug: Topiramate; Drug: Placebo
Sponsors: Brown University; National Institute on Drug Abuse (NIDA)
Recruiting - verified July 2011 - Conditions: HIV; Substance Abuse; HIV Infections
Interventions: Drug: Oral Naltrexone (ON); Drug: Implantable Naltrexone (IN)
Sponsors: University of Pennsylvania; National Institute on Drug Abuse (NIDA)
Not yet recruiting - verified January 2012 - Condition: Drug Dependence
Intervention: Drug: 2-4 of the drugs listed below
Sponsors: University of Arkansas; National Institute on Drug Abuse (NIDA)
Recruiting - verified August 2011 - Conditions: Schizophrenia; Schizoaffective Disorder
Intervention: Drug: Varenicline
Sponsors: Centre for Addiction and Mental Health; Pfizer
Recruiting - verified September 2011 - Condition: Tobacco Dependence
Intervention: Drug: nicotine patch
Sponsor: University of Massachusetts, Worcester
Recruiting - verified October 2011 - Conditions: Drug Abuse; Drug Dependence
Intervention:
Sponsor: Nantes University Hospital
Recruiting - verified January 2010 - Conditions: Alcohol Dependence; Problem Drinking; Hazardous Drinking; Human Immunodeficiency Virus; AIDS
Interventions: Drug: Vivitrol- Intramuscular naltrexone (depot-formulation); Drug: Placebo
Sponsors: Yale University; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified August 2011 - Condition: Cocaine Addiction
Intervention: Drug: Seromycin (D-cycloserine, DCS) or a placebo
Sponsors: University of Arkansas; National Institute on Drug Abuse (NIDA)
Recruiting - verified October 2011 - Condition: Depression
Interventions: Drug: Armodafinil; Drug: Armodafinil; Drug: Placebo
Sponsor: Cephalon
Recruiting - verified December 2011 - Conditions: Schizophrenia; Drug Abuse/Dependency
Intervention:
Sponsors: National Institute on Drug Abuse (NIDA); University of Maryland
Recruiting - verified May 2011 - Conditions: Drug Abuse; Nicotine Dependence
Intervention:
Sponsor: National Institute on Drug Abuse (NIDA)
Recruiting - verified June 2011 - Condition: Evaluation
Intervention:
Sponsor: National Institute on Drug Abuse (NIDA)
Recruiting - verified December 2011 - Conditions: Cocaine Dependence; Cannabis Dependence; Schizophrenia
Intervention:
Sponsors: National Institute on Drug Abuse (NIDA); University of Maryland
Recruiting - verified June 2011 - Conditions: Carcinoma; Bone Infection; Bone Fracture
Intervention: Other: PET bone scan
Sponsors: Alberta Health Services; Hamilton Health Sciences Corporation
Recruiting - verified August 2011 - Conditions: Alcohol Dependence; PTSD
Interventions: Drug: Propranolol; Drug: Placebo
Sponsors: Medical University of South Carolina; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified November 2011 - Condition: Substance Use Disorders
Intervention:
Sponsor: National Institute on Drug Abuse (NIDA)
Recruiting - verified January 2011 - Conditions: Drug Abuse; Cocaine Dependence
Intervention:
Sponsors: National Institute on Drug Abuse (NIDA); National Institute of Mental Health (NIMH)
Recruiting - verified July 2011 - Condition: Drug Abuse
Intervention:
Sponsor: National Institute on Drug Abuse (NIDA)
Recruiting - verified March 2011 - Condition: Tobacco Addiction
Intervention: Behavioral: Extended Duration Behavioral Smoking Cessation Counseling
Sponsors: Harvard University Faculty of Medicine; National Institute on Drug Abuse (NIDA)
Recruiting - verified June 2011 - Condition: Nicotine Dependence
Intervention: Device: Transcranial Magnetic Stimulation
Sponsors: National Institute on Drug Abuse (NIDA); University of Maryland
Recruiting - verified December 2011 - Condition: Cannabis Use
Intervention: Device: Repetitive Transcranial Magnetic Stimulation
Sponsors: National Institute on Drug Abuse (NIDA); University of Maryland
Not yet recruiting - verified December 2010 - Condition: Dependence, Cocaine
Intervention: Genetic: Collect 10 ml of Saliva for DNA extraction
Sponsor: Centre Hospitalier Universitaire de Fort-de-France
Recruiting - verified March 2011 - Condition: Opiate Addiction
Interventions: Drug: Buprenorphine/naloxone; Drug: Naltrexone
Sponsor: State University of New York at Buffalo
Recruiting - verified February 2011 - Condition: Attention Deficit Hyperactivity Disorder
Interventions: Dietary Supplement: Compound Natural Health Product; Dietary Supplement: Placebo
Sponsors: The Canadian College of Naturopathic Medicine; Health Canada; Centre for Addiction and Mental Health; SickKids Foundation
Not yet recruiting - verified October 2011 - Condition: Drug Dependence
Intervention: Drug: Oxytocin Nasal Spray
Sponsor: National Institute on Drug Abuse (NIDA)
Recruiting - verified July 2011 - Conditions: Substance-Related Disorders; Dual Diagnosis
Intervention:
Sponsor: Sorlandet Hospital HF
Recruiting - verified July 2011 - Conditions: Cocaine Abuse or Dependence; Cocaine Related Disorders
Intervention:
Sponsors: Wayne State University; National Institute on Drug Abuse (NIDA)
Recruiting - verified October 2011 - Conditions: Depressive Symptoms; Substance-related Disorders; Posttraumatic Stress Disorders
Interventions: Behavioral: ICBT: Integrated Cognitive Behavioral Therapy; Behavioral: CPT-M: Cognitive Processing Therapy-Modified
Sponsor: Department of Veterans Affairs
Recruiting - verified December 2011 - Conditions: Drug Abuse; Cocaine Dependence
Intervention:
Sponsor: National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2011 - Condition: Bipolar I Disorder
Interventions: Drug: Escitalopram; Drug: Bupropion XL
Sponsors: University of British Columbia; Canadian Institutes of Health Research (CIHR); Glaxo Smith Kline Biovail; H. Lundbeck A/S
Recruiting - verified September 2011 - Condition: Alcoholism
Interventions: Drug: Ethanol; Drug: Placebo; Drug: Diphenhydramine; Drug: Caffeine
Sponsors: University of Chicago; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified November 2011 - Condition: Alcohol Drinking
Interventions: Drug: D-cycloserine; Drug: Placebo
Sponsors: Central Institute of Mental Health, Mannheim; German Research Foundation
Recruiting - verified November 2011 - Condition: Alcohol Dependence
Interventions: Drug: Pregabalin; Drug: Duloxetine; Behavioral: Standardized behavioral therapy; Behavioral: Standardized behavioral therapy; Drug: Placebo; Behavioral: Standardized behavioral therapy
Sponsors: The Scripps Research Institute; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified June 2011 - Condition: Pathological Gambling
Intervention: Drug: Tolcapone
Sponsor: University of Minnesota - Clinical and Translational Science Institute
Recruiting - verified August 2011 - Condition: Opiate Addiction
Interventions: Other: Brief Intervention with Buprenorphine initiation; Behavioral: Brief Intervention
Sponsors: Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified December 2011 - Condition: Tardive Dyskinesia
Interventions: Drug: Pyridoxal 5'-Phosphate; Drug: Placebo
Sponsor: Medicure
Recruiting - verified September 2011 - Condition: Bone Scan
Intervention: Other: 18F-Sodium Fluoride (Na18F)
Sponsor: Alberta Health Services
Recruiting - verified August 2011 - Conditions: HIV Infections; Drug Abuse
Interventions: Drug: Disulfiram; Drug: Disulfiram + Efavirenz; Drug: Disulfiram + Atazanavir; Drug: Disulfiram + Ritonavir
Sponsors: University of California, San Francisco; National Institute on Drug Abuse (NIDA)
Recruiting - verified June 2011 - Conditions: Alzheimer's Disease; Agitation
Interventions: Drug: citalopram; Drug: placebo
Sponsors: Johns Hopkins University; National Institute on Aging (NIA); National Institute of Mental Health (NIMH)
Recruiting - verified September 2010 - Conditions: Alcohol Dependence; Depression
Interventions: Behavioral: Interpersonal Psychotherapy for Co-occurring Alcohol Dependence and Major Depression (IPT-ADMD); Behavioral: Treatment as Usual
Sponsors: University of Rochester; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified August 2011 - Conditions: Domestic Violence; Substance Abuse
Interventions: Behavioral: substance abuse/domestic violence treatment; Behavioral: Cognitive behavioral therapy addressing substance abuse
Sponsor: VU University of Amsterdam
Recruiting - verified January 2012 - Conditions: Bipolar; Depression
Intervention: Drug: lurasidone
Sponsor: Sunovion
Recruiting - verified January 2012 - Conditions: Domestic Violence; Substance Abuse
Interventions: Behavioral: substance abuse/domestic violence treatment; Behavioral: CBT addression paertner violence
Sponsor: VU University of Amsterdam
Recruiting - verified January 2012 - Conditions: Treatment for Cocaine Addiction; Lower Cocaine Use; Improve Memory; Impulse Control
Interventions: Drug: Modafinil; Drug: Placebo or sugar pill
Sponsors: Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2011 - Condition: Obsessive Compulsive Disorder
Interventions: Drug: clomipramine; Drug: escitalopram; Drug: duloxetine
Sponsors: Sunnybrook Health Sciences Centre; Obsessive Compulsive Foundation; Centre for Addiction and Mental Health
Recruiting - verified July 2011 - Cognitive Behavioral Social Skills Training for Patients With Late-Life Schizophrenia: a Pilot StudyCondition: Schizophrenia
Interventions: Behavioral: Cognitive Behavioral Social Skills Training (CBSST) plus treatment as usual; Behavioral: Treatment as usual (TAU)
Sponsor: Centre for Addiction and Mental Health
Recruiting - verified November 2011 - Conditions: Schizophrenia; Schizoaffective Disorder; Schizophreniform Disorder
Intervention: Drug: risperidone
Sponsor: Centre for Addiction and Mental Health
Recruiting - verified October 2011 - Condition: Substance Abuse
Interventions: Drug: Nicotine Replacement Treatment (NRT); Behavioral: Brief Advice
Sponsors: Brown University; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2009 - Condition: Obesity
Interventions: Radiation: PET scan; Procedure: Oral glucose tolerance test; Procedure: MRI; Behavioral: Psychological scales to assess attitudes and behaviors related to eating and quality of life; Other: Caloric Restriction
Sponsor: Vanderbilt University
Recruiting - verified February 2011 - Conditions: Psychological Stress; Drug Abuse
Intervention:
Sponsor: National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2011 - Conditions: Cocaine Dependence; Cocaine-Related Disorders; Opioid-Related Disorders
Interventions: Drug: Airipiprazole; Drug: Placebo
Sponsor: National Institute on Drug Abuse (NIDA)
Recruiting - verified July 2011 - Conditions: Smoking Cessation; Nicotine Dependence
Interventions: Drug: Nicotine Replacement Treatment (NRT); Drug: varenicline; Behavioral: Behavioral counseling for smoking cessation; Drug: Placebo patch; Drug: Placebo
Sponsors: Brown University; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2009 - Condition: Substance Use Disorders
Interventions: Behavioral: A Woman's Path to Recovery (WPR); Behavioral: Twelve-Step Facilitation (TSF)
Sponsor: Department of Veterans Affairs
Recruiting - verified October 2011 - Conditions: Alcohol Dependence; Dual Diagnosis; Drug Dependence
Intervention: Behavioral: In-Home-Messaging-Device (IHMDs)
Sponsor: Department of Veterans Affairs
Recruiting - verified October 2011 - Conditions: Schizophrenia; Schizoaffective Disorder; Schizophreniform Disorder; Delusional Disorder; Psychotic Disorder
Intervention: Drug: Risperidone/Olanzapine and PET scans
Sponsor: Centre for Addiction and Mental Health
Recruiting - verified October 2011 - Conditions: Alcohol Dependence; Anxiety Disorder
Intervention: Drug: disulfiram plus lorazepam
Sponsors: University of New Mexico; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified January 2012 - Conditions: Major Depressive Disorder; Dysthymic Disorder; Anxiety Disorders; Generalized Anxiety Disorder; Social Anxiety Disorder; Panic Disorder; Post-traumatic Stress Disorder
Interventions: Drug: Quetiapine; Drug: Placebo
Sponsor: Centre for Addiction and Mental Health
Recruiting - verified October 2011 - Conditions: Usual Aftercare; Oxford House; Therapeutic Community
Interventions: Other: Residential; Other: Residential
Sponsors: DePaul University; National Institute on Drug Abuse (NIDA)
Recruiting - verified June 2011 - Conditions: Bipolar Disorder; Cocaine Dependence
Intervention: Drug: Citicoline
Sponsors: University of Texas Southwestern Medical Center; National Institute on Drug Abuse (NIDA)
Recruiting - verified August 2011 - Conditions: Alcohol Dependence; Chronic Hepatitis C
Interventions: Behavioral: Motivational Enhancement Therapy (MET); Behavioral: Health education
Sponsor: Department of Veterans Affairs
Recruiting - verified October 2011 - Condition: Cocaine Related Disorders
Intervention:
Sponsor: National Institute on Drug Abuse (NIDA)
Recruiting - verified September 2011 - Condition: Marijuana Abuse
Interventions: Behavioral: Motivational Enhancement Therapy (MET)/CBT+CM; Behavioral: Motivational Enhancement Therapy (MET)/CBT+CM; Behavioral: Motivational Enhancement Therapy (MET)/CBT
Sponsors: University of Arkansas; National Institutes of Health (NIH)
Recruiting - verified September 2011 - Condition: Cocaine Addiction
Interventions: Behavioral: I/GDC + VR/CER; Behavioral: I/GDC
Sponsors: Duke University; National Institute on Drug Abuse (NIDA)
Recruiting - verified June 2011 - Conditions: Cocaine Dependent; Alcohol Dependent
Interventions: Drug: Guanfacine; Drug: Placebo
Sponsors: Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified August 2011 - Condition: Cocaine Addictions
Interventions: Drug: sugar pill; Drug: carvedilol; Drug: Methadone
Sponsors: Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified December 2011 - Condition: Depression
Intervention: Drug: escitalopram
Sponsors: Centre for Addiction and Mental Health; Queen's University
Recruiting - verified January 2012 - Conditions: Mycoses; Candidiasis, Invasive; Candidemia
Interventions: Drug: Isavuconazole; Drug: Caspofungin; Drug: Voriconazole
Sponsors: Astellas Pharma Inc; Basilea Pharmaceutica
Recruiting - verified January 2012 - Condition: Tobacco Use Disorder
Intervention: Procedure: PET Brain Imaging
Sponsor: Hadassah Medical Organization
Recruiting - verified July 2011 - Condition: Smoking
Interventions: Drug: nicotine replacement; Behavioral: behavioural intervention
Sponsors: Centre for Addiction and Mental Health; Pfizer; Ontario Ministry of Health and Long Term Care
Recruiting - verified June 2011 - Conditions: Pain; Hypogonadism
Interventions: Drug: Androgel (testosterone gel); Other: Placebo
Sponsor: Boston University
Recruiting - verified March 2011 - Condition: Huntington Disease
Intervention:
Sponsors: HP Therapeutics Foundation; Huntington Study Group
Recruiting - verified March 2011 - Conditions: Smoking; Tobacco Use Cessation
Interventions: Behavioral: MBAT Group Therapy; Drug: Nicotine; Behavioral: Group Therapy; Behavioral: Individual Therapy
Sponsors: M.D. Anderson Cancer Center; National Institute on Drug Abuse (NIDA)
Recruiting - verified November 2011 - Condition: Cocaine-Related Disorders
Intervention: Drug: Aripiprazole
Sponsors: University of Kentucky; National Institute on Drug Abuse (NIDA)
Recruiting - verified October 2011 - Conditions: Alcoholism; Alcohol Dependence; Alcohol Drinking Related Problems
Intervention:
Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified October 2011 - Condition: Alcoholism
Interventions: Drug: ondansetron + cognitive behavioral therapy; Drug: topiramate + cognitive behavioral therapy; Drug: Placebo + cognitive behavioral therapy; Drug: ondansetron + topiramate + cognitive behavioral therapy
Sponsors: Bankole Johnson; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified February 2012
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