Takeda Pharma - Database of Clinical Trials by Pharmaceutical Companies

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Double Blind Comparative Study of TAK-875

Condition: Diabetic Patients
Interventions: Drug: TAK-875; Drug: TAK-875; Drug: Glimepiride; Drug: Placebo
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Pharmaceutical Company Limited
Not yet recruiting - verified May 2012
Efficacy and Safety of Actovegin in Post-stroke Cognitive Impairment (PSCI)

Condition: Post-Stroke Cognitive Impairment (PSCI)
Interventions: Drug: Actovegin; Drug: Placebo
Sponsors: Nycomed; Nycomed
Not yet recruiting - verified April 2012
A Unblinded Study of TAK-438 (20 mg) for Prevention of Recurrence of Gastric or Duodenal Ulcer During Long-Term Low-Dose Aspirin Therapy

Conditions: Gastric Ulcer; Duodenal Ulcer
Intervention: Drug: TAK-438
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Pharmaceutical Company Limited
Not yet recruiting - verified April 2012
A Unblinded Study of TAK-438 (20 mg) for Prevention of Recurrence of Gastric or Duodenal Ulcer During Long-Term Non-Steroid Anti-Inflammatory Drug (NSAID) Therapy

Conditions: Gastric Ulcer; Duodenal Ulcer
Intervention: Drug: TAK-438
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Pharmaceutical Company Limited
Not yet recruiting - verified April 2012
Efficacy of LuAA21004 on Cognitive Dysfunction in Major Depressive Disorder

Condition: Depressive Disorder, Major
Interventions: Drug: LuAA21004; Drug: Duloxetine; Drug: Placebo
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Global Research & Development Center, Inc.
Recruiting - verified May 2012
Myocardial Dysfunction in Type 2 Diabetes Mellitus (T2DM)

Conditions: Type 2 Diabetes; Coronary Heart Disease
Intervention: Drug: pioglitazone
Sponsors: The University of Texas Health Science Center at San Antonio; The University of Texas Health Science Center at San Antonio; Takeda Pharmaceuticals North America, Inc.
Completed - verified April 2012
Effect of Febuxostat Compared to Placebo on Exercise Tolerance in Participants With Chronic Stable Angina

Condition: Angina
Interventions: Drug: Febuxostat; Drug: Placebo
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Global Research & Development Center, Inc.
Recruiting - verified April 2012
Comparison of TAK-875 to Placebo and Sitagliptin in Combination With Metformin in Participants With Type 2 Diabetes

Condition: Glycemic Control
Interventions: Drug: TAK-875; Drug: Sitagliptin; Drug: Placebo
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Global Research & Development Centre (Europe) Ltd.
Recruiting - verified May 2012
A Phase 3 Comparative Study of TAP-144-SR(6M) in Postoperative and Hormone Therapy-naïve Patients With Premenopausal Breast Cancer

Condition: Premenopausal Breast Cancer
Interventions: Drug: TAP-144-SR(6M); Drug: TAP-144-SR(3M)
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Pharmaceutical Company Limited
Recruiting - verified April 2012
A Phase 3 Comparative Study of TAP-144-SR(6M) in Prostate Cancer Patients Previously Treated With Hormonal Therapy

Condition: Prostate Cancer
Interventions: Drug: TAP-144-SR(6M); Drug: TAP-144-SR(3M)
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Pharmaceutical Company Limited
Recruiting - verified April 2012
LIpid Lowering With Highly Potent Statins in Hyperlipidaemia With Type 2 Diabetes patiENts

Condition: Hypercholesterolemia With Concomitant Type 2 Diabetes
Interventions: Drug: Atorvastatin; Drug: Rosuvastatin
Sponsors: Listen Trial Group; Listen Trial Group
Recruiting - verified April 2012
Study of Combination Therapy With SYR-322

Condition: Diabetes Mellitus
Interventions: Drug: Alogliptin; Drug: Insulin
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Pharmaceutical Company Limited
Recruiting - verified May 2012
Efficacy of TAK-438, Amoxicillin and Clarithromycin in the Primary Eradication of H. Pylori

Condition: H. Pylori Infection
Interventions: Drug: TAK-438; Drug: Lansoprazole; Drug: Amoxicillin; Drug: Clarithromycin
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Pharmaceutical Company Limited
Recruiting - verified May 2012
Reflux Disease Therapy in the Management of Childhood Asthma-data Entry and Analysis Only

Conditions: Asthma; Gastroesophageal Reflux Disease
Intervention:
Sponsors: Children's Center for Digestive Health Care; Children's Center for Digestive Health Care; Takeda Pharmaceuticals North America, Inc.
Active, not recruiting - verified February 2012
Effect of Febuxostat on Blood Pressure

Condition: Hypertension
Interventions: Drug: Febuxostat; Drug: Placebo
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Global Research & Development Center, Inc.
Recruiting - verified March 2012
TAK-875 Glimepiride Drug-Interaction Study

Condition: Pharmacokinetics
Intervention: Drug: TAK-875 and Glimepiride
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Global Research & Development Center, Inc.
Recruiting - verified February 2012
Efficacy and Safety of Azilsartan Medoxomil Used in Combination With Metformin in Participants With Hypertension and Diabetes

Conditions: Hypertension; Diabetes
Interventions: Drug: Placebo; Drug: Azilsartan medoxomil; Drug: Azilsartan medoxomil
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Global Research & Development Center, Inc.
Recruiting - verified March 2012
Trial to Assess the Anti-inflammatory Effects of Roflumilast in Chronic Obstructive Pulmonary Disease

Conditions: COPD; Chronic Obstructive Pulmonary Disease
Interventions: Drug: Roflumilast; Drug: Placebo
Sponsors: Nycomed; Nycomed
Recruiting - verified May 2012
Comparison of Efficacy and Safety of TachoSil® Versus Surgicel® Original for the Secondary Hemostatic Treatment in Vascular Surgery

Condition: Bleeding
Interventions: Drug: TachoSil®; Drug: Surgicel® Original
Sponsors: Nycomed; Nycomed; Baxter US
Recruiting - verified April 2012
Does Ketamine Attenuate Depression of Respiratory and Cardiac Functions

Conditions: Congenital Heart Disease; Cardiac Catheterization
Interventions: Drug: saline with propofol; Drug: ketamine with propofol; Drug: ketamine with propofol
Sponsors: Ibaraki Children's Hospital; Ibaraki Children's Hospital
Recruiting - verified January 2012
Efficacy and Safety of TAK-875 Compared to Glimepiride When Used With Metformin in Participants With Type 2 Diabetes

Condition: Diabetes Mellitus, Type 2
Interventions: Drug: TAK-875; Drug: TAK-875; Drug: Glimepiride
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Global Research & Development Center, Inc.
Recruiting - verified May 2012
Conversion Study From Epoetin Alfa to Monthly Peginesatide Injection in Patients With Chronic Kidney Disease on Dialysis

Conditions: Chronic Kidney Disease; Anemia
Intervention: Drug: peginesatide injection
Sponsors: Affymax; Affymax; Takeda Pharmaceutical Company Limited
Active, not recruiting - verified February 2012
Efficacy and Safety of Ramelteon Sublingual as Adjunctive Therapy for Maintenance Treatment of Bipolar I Disorder in Adult Patients

Condition: Bipolar Disorder
Interventions: Drug: Ramelteon SL; Drug: Ramelteon SL; Drug: Ramelteon SL; Drug: Placebo
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Global Research & Development Center, Inc.
Recruiting - verified March 2012
Efficacy and Safety of Ramelteon Sublingual in Adult Patients With Acute Depressive Episodes Associated With Bipolar I Disorder

Condition: Acute Depressive Episode
Interventions: Drug: Ramelteon SL; Drug: Ramelteon SL; Drug: Ramelteon SL; Drug: Placebo
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Global Research & Development Center, Inc.
Recruiting - verified March 2012
Study of Febuxostat Effect on Blood Pressure in Patients With High Normal Blood Pressure

Conditions: Prehypertension; Gout; Pulse Wave Velocity; Hypertension; 24 Hour Blood Pressure
Intervention: Drug: Febuxostat
Sponsors: University of California, San Diego; University of California, San Diego; Takeda Global Research & Development Center, Inc.
Recruiting - verified November 2011
Efficacy of TAK-438 Compared to Placebo in the Treatment of Non-Erosive Gastroesophageal Reflux Disease

Condition: Non-erosive Gastroesophageal Reflux Disease
Interventions: Drug: TAK-438; Drug: TAK-438; Drug: Placebo
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Pharmaceutical Company Limited
Recruiting - verified December 2011
Efficacy of TAK-438 Compared to AG-1749 (Lansoprazole) in the Maintenance Treatment of Healed Erosive Esophagitis

Condition: Erosive Esophagitis
Interventions: Drug: TAK-438; Drug: TAK-438; Drug: Lansoprazole
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Pharmaceutical Company Limited
Recruiting - verified January 2012
Effect of Roflumilast at Acute Exacerbations of Chronic Obstructive Pulmonary Disease

Condition: Chronic Obstructive Pulmonary Disease With (Acute) Exacerbation
Interventions: Drug: Roflumilast; Drug: Placebo
Sponsors: Nycomed; Nycomed
Recruiting - verified May 2012
Comparison of TAK-875 With Placebo in Participants With Type 2 Diabetes

Condition: Diabetes Mellitus, Type 2
Interventions: Drug: Placebo; Drug: TAK-875; Drug: TAK-875
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Global Research & Development Center, Inc.
Recruiting - verified May 2012
Study to Assess the Effects of Daily Administration of Pioglitazone on Brain Hemodynamics in Healthy Elderly Participants

Condition: Healthy
Interventions: Drug: Pioglitazone; Drug: Pioglitazone; Drug: Pioglitazone; Drug: Placebo
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Global Research & Development Center, Inc.
Recruiting - verified March 2012
A Study to Evaluate the Effectiveness and Safety of TAK-491(Azilsartan Medoxomil) and Chlorthalidone Combined in One Tablet (40/12.5 and 40/25 mg) in Patients With High Blood Pressure Who do Not Achieve Target Blood Pressure on Treatment With TAK-491 40 mg Alone

Condition: Essential Hypertension
Interventions: Drug: Azilsartan medoxomil; Drug: Azilsartan medoxomil and chlorthalidone; Drug: Azilsartan medoxomil and chlorthalidone
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Global Research & Development Centre (Europe) Ltd.
Recruiting - verified January 2012
Lubiprostone Effect on Gastrointestinal (GI) Tract Transit Times Measured by Smartpill in Patients With Chronic Constipation

Condition: Chronic Idiopathic Constipation
Intervention: Drug: Lubiprostone
Sponsors: Texas Tech University Health Sciences Center; Texas Tech University Health Sciences Center; Takeda Pharmaceuticals North America, Inc.
Not yet recruiting - verified November 2011
Long-term Study of SYR-322

Condition: Diabetes Mellitus
Intervention: Drug: Alogliptin
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Pharmaceutical Company Limited
Recruiting - verified February 2012
Effect of High Dose Ciclesonide on Asthma Control

Condition: Bronchial Asthma
Intervention: Drug: Ciclesonide
Sponsors: Nycomed; Nycomed
Recruiting - verified May 2012
Characterization of the Variability of Insulin Secretory Parameters in the Meal Tolerance and the Maximal Stimulation Tests of Healthy Subjects

Condition: Type 2 Diabetes
Intervention:
Sponsors: Foundation for the National Institutes of Health; Foundation for the National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Juvenile Diabetes Research Foundation; Amylin Pharmaceuticals, Inc.; Merck; Pfizer; Eli Lilly and Company; Takeda Global Research & Development Center, Inc.; Johnson & Johnson Pharmaceutical Research & Development, L.L.C.; Novartis
Recruiting - verified October 2011
Efficacy and Safety of TAK-438 for the Prevention of Recurrent Gastric or Duodenal Ulcers During Therapy of Low-dose Aspirin

Conditions: Gastric Ulcers; Duodenal Ulcers
Interventions: Drug: TAK-438; Drug: Placebo; Drug: TAK-438; Drug: Placebo; Drug: Lansoprazole; Drug: Placebo
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Pharmaceutical Company Limited
Recruiting - verified January 2012
Long-term Extension Study of TAK-438 for the Prevention of Recurrent Gastric or Duodenal Ulcers During Therapy of Low-dose Aspirin

Conditions: Gastric Ulcers; Duodenal Ulcers
Interventions: Drug: TAK-438; Drug: Placebo; Drug: TAK-438; Drug: Placebo; Drug: Lansoprazole; Drug: Placebo
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Pharmaceutical Company Limited
Recruiting - verified January 2012
Efficacy of TAK-438 Compared to AG-1749 (Lansoprazole) in the Treatment of Gastric Ulcer

Condition: Gastric Ulcer
Interventions: Drug: TAK-438; Drug: Placebo; Drug: Lansoprazole; Drug: Placebo
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Pharmaceutical Company Limited
Recruiting - verified May 2012
Efficacy and Safety of TAK-438 Compared to AG-1749 (Lansoprazole) in the Treatment of Duodenal Ulcer

Condition: Duodenal Ulcer
Interventions: Drug: TAK-438; Drug: Placebo; Drug: Lansoprazole; Drug: Placebo
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Pharmaceutical Company Limited
Recruiting - verified May 2012
Long-term Extension Study of TAK-438 for the Prevention of Recurrent Gastric or Duodenal Ulcers During Therapy of Non-steroidal Anti-inflammatory Drug (NSAID)

Conditions: Gastric Ulcers; Duodenal Ulcers
Interventions: Drug: TAK-438; Drug: Placebo; Drug: TAK-438; Drug: Placebo; Drug: Lansoprazole; Drug: Placebo
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Pharmaceutical Company Limited
Recruiting - verified January 2012
Efficacy and Safety of TAK-438 for the Prevention of Recurrent Gastric or Duodenal Ulcers During Therapy of Non-steroidal Anti-inflammatory Drug (NSAID)

Conditions: Gastric Ulcers; Duodenal Ulcers
Interventions: Drug: TAK-438; Drug: Placebo; Drug: TAK-438; Drug: Placebo; Drug: Lansoprazole; Drug: Placebo
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Pharmaceutical Company Limited
Recruiting - verified January 2012
Efficacy of TAK-438 Compared to AG-1749 (Lansoprazole) in the Treatment of Erosive Esophagitis

Condition: Erosive Esophagitis
Interventions: Drug: TAK-438; Drug: Placebo; Drug: Lansoprazole; Drug: Placebo
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Pharmaceutical Company Limited
Recruiting - verified January 2012
Long-Term Safety Study of TAK-438 in the Maintenance Treatment of Healed Erosive Esophagitis

Condition: Erosive Esophagitis
Interventions: Drug: TAK-438; Drug: TAK-438
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Pharmaceutical Company Limited
Recruiting - verified January 2012
Double-blind Comparative Study of TAK-875

Condition: Diabetes Mellitus
Interventions: Drug: TAK-875; Drug: TAK-875; Drug: Placebo
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Pharmaceutical Company Limited
Recruiting - verified January 2012
Open-label Study of TAK-875

Condition: Diabetes Mellitus
Interventions: Drug: TAK-875; Drug: TAK-875
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Pharmaceutical Company Limited
Recruiting - verified January 2012
Long-term Study of TAK-875

Condition: Diabetes Mellitus
Interventions: Drug: TAK-875; Drug: TAK-875
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Pharmaceutical Company Limited
Recruiting - verified January 2012
Long-term Study of SYR-472

Condition: Diabetes Mellitus
Intervention: Drug: SYR-472
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Pharmaceutical Company Limited
Recruiting - verified January 2012
Efficacy and Safety of TAK-385 in the Treatment of Endometriosis

Condition: Endometriosis
Interventions: Drug: Placebo; Drug: TAK-385; Drug: TAK-385; Drug: TAK-385; Drug: Leuprorelin acetate
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Pharmaceutical Company Limited
Recruiting - verified February 2012
Efficacy and Safety of TAK-385 in the Treatment of Uterine Fibroids

Condition: Uterine Fibroids
Interventions: Drug: TAK-385; Drug: TAK-385; Drug: TAK-385; Drug: Placebo
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Pharmaceutical Company Limited
Recruiting - verified January 2012
A Long-term Extension Study of TAK-385 in the Treatment of Endometriosis

Condition: Endometriosis
Interventions: Drug: Placebo; Drug: TAK-385; Drug: TAK-385; Drug: TAK-385; Drug: Leuprorelin acetate
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Pharmaceutical Company Limited
Recruiting - verified April 2012
A Clinical Trial With Intranasal Fentanyl in Cancer Patients With Breakthrough Pain

Conditions: Break Through Pain; Cancer
Intervention: Drug: Intranasal Fentanyl Spray (INFS)
Sponsors: Nycomed; Nycomed
Recruiting - verified May 2012
This is a Multicenter, Prospective and Retrospective and Descriptive Epidemiology Study in Patients With Chronic Obstructive Pulmonary Disease (COPD) in Korea

Condition: COPD
Intervention:
Sponsors: Nycomed; Nycomed
Recruiting - verified May 2012
Efficacy and Safety of TAK-875 in Combination With Sitagliptin in Participants With Type 2 Diabetes Mellitus

Condition: Diabetes Mellitus, Type 2
Interventions: Drug: Placebo; Drug: TAK-875; Drug: TAK-875; Drug: Sitagliptin; Drug: TAK-875 and Sitagliptin; Drug: TAK-875 and Sitagliptin
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Global Research & Development Center, Inc.
Active, not recruiting - verified May 2012
CLinical Prediction Rule Score in Veterans

Condition: Gout
Intervention:
Sponsors: Minneapolis Veterans Affairs Medical Center; jasvinder singh; Department of Veterans Affairs; Takeda Global Research & Development Center, Inc.; Novartis; Regeneron Pharmaceuticals
Active, not recruiting - verified April 2012
Long-Term Extension Study of Lu AA21004 in Participants With Major Depressive Disorder

Condition: Major Depressive Disorder
Intervention: Drug: Lu AA21004
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Pharmaceutical Company Limited
Recruiting - verified November 2011
Pharmacokinetics and Pharmacodynamics Study of Alogliptin in Healthy Korean Participants

Condition: Pharmacokinetics and Pharmacodynamics
Interventions: Drug: Alogliptin; Drug: Alogliptin; Drug: Alogliptin
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Global Research & Development Center (Asia) Pte. Ltd
Completed - verified September 2011
Study of TAK-816 in Healthy Infants

Condition: Immunization
Interventions: Biological: TAK-816+ DPT-TAKEDA; Biological: ActHIB+ DPT-TAKEDA
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Pharmaceutical Company Limited
Active, not recruiting - verified March 2012
Effect of Lu AA21004 Versus Escitalopram on Sexual Functioning in Adults With Well-Treated Major Depressive Disorder

Condition: Treatment Outcome
Interventions: Drug: Lu AA21004; Drug: Escitalopram
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Global Research & Development Center, Inc.
Recruiting - verified February 2012