- Condition: Systemic Lupus Erythematosus
Intervention: Drug: Belimumab
Sponsors: GlaxoSmithKline; GlaxoSmithKline; Human Genome Sciences
Not yet recruiting - verified May 2012 - Conditions: Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic
Interventions: Drug: R932333; Drug: Placebo
Sponsors: Rigel Pharmaceuticals; Rigel Pharmaceuticals
Not yet recruiting - verified May 2012 - Condition: Lupus Erythematosus, Systemic
Interventions: Biological: Belimumab plus Early Vaccination; Biological: Belimumab plus Late Vaccination
Sponsors: Human Genome Sciences; Human Genome Sciences; GlaxoSmithKline
Not yet recruiting - verified May 2012 - Condition: Systemic Lupus Erythematosus
Interventions: Drug: MEDI-546; Drug: MEDI-546; Drug: MEDI-546
Sponsors: AstraZeneca; AstraZeneca; MedImmune LLC
Recruiting - verified April 2012 - Conditions: Chemical Injuries; Unspecified Complication of Corneal Transplant; Autoimmune Diseases; Ocular Cicatricial Pemphigoid; Stevens Johnson Syndrome; Lupus Erythematosus, Systemic; Rheumatoid Arthritis; Other Autoimmune Diseases
Intervention: Drug: Riboflavin
Sponsors: Massachusetts Eye and Ear Infirmary; Massachusetts Eye and Ear Infirmary
Recruiting - verified April 2012 - Condition: Cutaneous Lupus Erythematosus-Systemic Lupus Erythematosus
Interventions: Drug: hydroxychloroquine (Z0188); Drug: Placebo
Sponsors: Sanofi-Aventis; Sanofi-Aventis
Recruiting - verified April 2012 - Condition: Lupus Nephritis
Intervention: Drug: Tacrolimus vs. Mycophenolate mofetil for Induction Therapy in Lupus Nephritis
Sponsors: Ramathibodi Hospital; Ramathibodi Hospital; King Chulalongkorn Memorial Hospital; Maharaj Nakorn Chiang Mai Hospital; Rajavithi Hospital; Srinagarind Hospital; Siriraj Hospital; Songklanagarind Hospital
Not yet recruiting - verified April 2012 - Conditions: Pemphigoid, Bullous; Pemphigus; Lupus Erythematosus, Cutaneous
Intervention:
Sponsors: Centre Hospitalier Universitaire de Nīmes; Centre Hospitalier Universitaire de Nīmes
Not yet recruiting - verified March 2012 - Condition: Systemic Lupus Erythematosus
Intervention: Drug: Anti-Macrophage Migration Inhibitory Factor (Anti-MIF) Antibody
Sponsors: Baxter Healthcare Corporation; Baxter Healthcare Corporation
Recruiting - verified March 2012 - Conditions: Systemic Lupus Erythematosus; Pregnancy
Intervention: Drug: belimumab
Sponsors: GlaxoSmithKline; GlaxoSmithKline
Recruiting - verified February 2012 - Condition: Systemic Lupus Erythematosus
Intervention: Behavioral: Exercise training
Sponsors: University of Sao Paulo; University of Sao Paulo
Recruiting - verified January 2012 - Condition: Lupus Nephritis
Interventions: Biological: Human Umbilical Cord derived MSCs; Drug: Cyclophosphamide
Sponsors: CytoMed & Beike; CytoMed & Beike
Recruiting - verified March 2012 - Conditions: Lupus Erythematosus; Photosensitivity
Intervention: Other: Phototesting
Sponsors: University of Pennsylvania; University of Pennsylvania
Recruiting - verified January 2012 - Condition: Cutaneous Lupus Erythematosus
Intervention:
Sponsors: University of Pennsylvania; University of Pennsylvania
Recruiting - verified January 2012 - Condition: Systemic Lupus Erythematosus
Intervention:
Sponsors: Johann Wolfgang Goethe University Hospitals; Johann Wolfgang Goethe University Hospitals
Recruiting - verified January 2012 - Condition: Systemic Lupus Erythematosus
Intervention:
Sponsors: Assistance Publique - Hôpitaux de Paris; Assistance Publique - Hôpitaux de Paris
Not yet recruiting - verified November 2011 - A Study of Belimumab Administered Subcutaneously in Subjects With Systemic Lupus Erythematosus (SLE)Condition: Systemic Lupus Erythematosus
Interventions: Drug: Placebo; Drug: Belimumab 200 mg SC
Sponsors: Human Genome Sciences; Human Genome Sciences; GlaxoSmithKline
Recruiting - verified January 2012 - Condition: Cutaneous Lupus Erythematosus
Intervention: Dietary Supplement: vitamin D
Sponsors: Emory University; Emory University; Dermatology Foundation
Recruiting - verified January 2012 - Condition: Systemic Lupus Erythematosus
Intervention: Drug: Zostavax vaccine
Sponsors: Oklahoma Medical Research Foundation; Oklahoma Medical Research Foundation
Recruiting - verified November 2011 - Conditions: Antiphospholipid Syndrome; Thrombophilia Due to Antiphospholipid Antibody; Systemic Lupus Erythematosus
Intervention: Other: Phlebotomy
Sponsors: Hospital for Special Surgery, New York; Hospital for Special Surgery, New York; Michael D. Lockshin, MD - Hospital for Special Surgery; Jacob H. Rand, MD - Montefiore Medical Center
Recruiting - verified November 2011 - Conditions: Lupus Erythematosus, Systemic; Arthritis, Rheumatoid
Intervention:
Sponsors: Federal University of São Paulo; Federal University of São Paulo
Recruiting - verified November 2011 - Condition: Lupus Nephritis
Interventions: Drug: BIIB023; Drug: Placebo
Sponsors: Biogen Idec; Biogen Idec; Biogen Idec Australia Pty Ltd; Biogen Idec Research Ltd.; Biogen Idec MA Inc.
Recruiting - verified May 2012 - Condition: Cutaneous Lupus Erythematosus
Interventions: Drug: PD-0360324; Drug: Placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Conditions: Fibromyalgia; Systemic Lupus Erythematosus
Intervention:
Sponsors: Tel-Aviv Sourasky Medical Center; Tel-Aviv Sourasky Medical Center
Not yet recruiting - verified October 2011 - Condition: Discoid Lupus
Interventions: Drug: CC-930; Drug: Placebo
Sponsors: Celgene Corporation; Celgene Corporation
Recruiting - verified March 2012 - Condition: Systemic Lupus Erythematosus
Interventions: Biological: Placebo; Biological: Epratuzumab 400 mg; Biological: Epratuzumab 1200 mg; Biological: Epratuzumab 100 mg; Biological: Epratuzumab 600 mg
Sponsors: UCB, Inc.; UCB, Inc.
Recruiting - verified April 2012 - Condition: Lupus Nephritis
Intervention:
Sponsors: Columbia University; Columbia University; Centocor Research & Development, Inc.
Recruiting - verified November 2011 - Condition: Systemic Lupus Erythematosus
Interventions: Biological: MEDI-546; Biological: MEDI-546; Other: Placebo
Sponsors: MedImmune LLC; MedImmune LLC
Recruiting - verified April 2012 - Conditions: Interstitial Lung Disease; Connective Tissue Disease
Intervention: Drug: N-Acetylcysteine
Sponsors: University of Michigan; University of Michigan
Recruiting - verified December 2011 - Condition: Lupus Erythematosus, Systemic
Interventions: Biological: PF-04236921; Biological: PF-04236921; Biological: PF-04236921; Biological: PF-04236921
Sponsors: Pfizer; Pfizer
Recruiting - verified April 2012 - Conditions: Rheumatoid Arthritis; Systemic Lupus Erythematosus; Osteoarthritis; Post-traumatic Arthritis
Intervention: Device: Ascension MCP Finger Implant
Sponsors: Ascension Orthopedics, Inc.; Ascension Orthopedics, Inc.
Recruiting - verified July 2011 - Condition: Systemic Lupus Erythematosus
Interventions: Drug: blisibimod; Drug: blisibimod; Drug: Placebo
Sponsors: Anthera Pharmaceuticals; Anthera Pharmaceuticals
Not yet recruiting - verified December 2011 - Condition: Lupus Erythematosus, Cutaneous
Intervention: Drug: Alitretinoin
Sponsors: University Hospital Muenster; University Hospital Muenster; Basilea Pharmaceutica International Ltd
Not yet recruiting - verified May 2011 - Conditions: Rheumatoid Arthritis; Lupus Erythematosus, Systemic; Sjogren's Syndrome
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Environmental Health Sciences (NIEHS)
Recruiting - verified May 2012 - Conditions: Dry Eye; Sjogren's Syndrome; Graft vs. Host Disease
Intervention: Drug: Thymosin Beta 4 eye drops vs. vehicle
Sponsors: Michigan Cornea Consultants, PC; Michigan Cornea Consultants, PC; Kresge Eye Institute
Recruiting - verified July 2011 - Condition: Lupus Nephritis
Intervention: Drug: Tacrolimus
Sponsors: Astellas Pharma Inc; Astellas Pharma Inc
Recruiting - verified August 2011 - Conditions: Congenital Heart Block; Neonatal Lupus; Autoantibody-Associated Heart Block
Intervention: Drug: Hydroxychloroquine
Sponsors: New York University School of Medicine; New York University School of Medicine
Recruiting - verified June 2011 - Conditions: Cutaneous Lupus; Lupus
Interventions: Drug: AMG 557; Drug: AMG 557 Placebo
Sponsors: Amgen; Amgen
Recruiting - verified April 2012 - Condition: Systemic Lupus Erythematosus
Interventions: Drug: Belimumab; Drug: Placebo
Sponsors: GlaxoSmithKline; GlaxoSmithKline; Human Genome Sciences
Recruiting - verified March 2012 - Conditions: Systemic Lupus Erythematosus; Widespread Pain; Fibromyalgia
Intervention: Drug: Milnacipran
Sponsors: Loma Linda University; Emmanuel Katsaros; Forest Laboratories
Recruiting - verified October 2011 - Condition: Lupus Erythematosus, Cutaneous
Intervention: Drug: Fumaric acid esters
Sponsors: University Hospital Muenster; University Hospital Muenster
Recruiting - verified July 2011 - Condition: Lupus Nephritis
Interventions: Drug: tacrolimus capsule; Drug: tacrolimus placebo; Drug: leflunomide tablet; Drug: leflunomide placebo; Drug: prednisone
Sponsors: Astellas Pharma Inc; Astellas Pharma Inc; Astellas Pharma China, Inc.
Recruiting - verified October 2011 - Condition: Lupus Nephritis
Intervention: Drug: tacrolimus
Sponsors: Astellas Pharma Inc; Astellas Pharma Inc; Astellas Pharma Korea, Inc.
Recruiting - verified October 2011 - Condition: Systemic Lupus Erythematosus
Interventions: Drug: Sifalimumab; Drug: Sifalimumab; Drug: Sifalimumab; Drug: Placebo
Sponsors: MedImmune LLC; MedImmune LLC
Recruiting - verified January 2012 - Condition: Subacute Cutaneous Lupus Erythematosus
Interventions: Drug: KRP203 1.2 mg; Other: Placebo - 1.2 mg
Sponsors: Novartis; Novartis Pharmaceuticals
Recruiting - verified April 2012 - Conditions: Lupus Nephritis; Kidney Diseases; Kidney Insufficiency; Glomerulonephritis; Systemic Lupus Erythematosus
Interventions: Drug: CNTO 136; Drug: Placebo
Sponsors: Centocor, Inc.; Centocor, Inc.
Recruiting - verified April 2012 - Condition: Systemic Lupus Erythematosus
Intervention: Drug: Cymbalta
Sponsors: Brain Resource Center; Brain Resource Center
Recruiting - verified December 2010 - Condition: Systemic Lupus Erythematosus
Interventions: Drug: Epratuzumab; Drug: Epratuzumab; Drug: Placebo
Sponsors: UCB, Inc.; UCB, Inc.
Recruiting - verified May 2012 - Condition: Systemic Lupus Erythematosus
Interventions: Drug: Placebo; Drug: Epratuzumab; Drug: Epratuzumab
Sponsors: UCB, Inc.; UCB, Inc.
Recruiting - verified May 2012 - Condition: Systemic Lupus Erythematosus
Intervention:
Sponsors: Children's Hospital of Philadelphia; Children's Hospital of Philadelphia
Recruiting - verified December 2011 - Conditions: Lupus Erythematosus, Systemic; Systemic Vasculitis; Isolated Angiitis of Central Nervous System; Lung Disease With Systemic Sclerosis; Lung Disease Interstitial Diffuse
Interventions: Drug: depot leuprolide acetate 3.75 mg; Drug: Placebo
Sponsors: University of Michigan; Joseph Mccune; National Institutes of Health (NIH)
Recruiting - verified February 2012 - Conditions: Juvenile Systemic Lupus Erythematosus; Juvenile Dermatomyositis
Interventions: Dietary Supplement: creatine; Dietary Supplement: placebo (dextrose)
Sponsors: University of Sao Paulo; University of Sao Paulo
Recruiting - verified January 2012 - Condition: Cutaneous Lupus Erythematosus
Intervention: Drug: CC-11050
Sponsors: Celgene Corporation; Celgene Corporation
Recruiting - verified February 2012 - Conditions: Systemic Lupus Erythematosus; Connective Tissue Disease; Autoimmune Disease
Interventions: Drug: LY2127399; Drug: Placebo every 2 weeks; Drug: Placebo every 4 weeks
Sponsors: Eli Lilly and Company; Eli Lilly and Company
Recruiting - verified April 2012 - Condition: Lupus Nephritis
Intervention: Drug: Tamibarotene
Sponsors: Kinki University; Kinki University
Recruiting - verified July 2011 - Conditions: Systemic Lupus Erythematosus; Connective Tissue Disease; Autoimmune Disease
Interventions: Drug: LY2127399; Drug: Placebo every 2 weeks; Drug: Placebo every 4 weeks
Sponsors: Eli Lilly and Company; Eli Lilly and Company
Recruiting - verified April 2012 - Condition: Lupus Nephritis
Intervention: Drug: low dose combination of MMF and Tac
Sponsors: Tuen Mun Hospital; Tuen Mun Hospital
Recruiting - verified October 2011 - Condition: Systemic Lupus Erythematosus
Intervention: Other: Standard care plus Yoga
Sponsors: McGill University Health Center; McGill University Health Center
Recruiting - verified July 2011 - Conditions: Atherosclerosis; Systemic Lupus Erythematosus
Interventions: Drug: Rosuvastatin; Drug: Placebo
Sponsors: Imperial College London; Imperial College London
Recruiting - verified August 2011 - Conditions: Cutaneous Lupus; Discoid Lupus; Lupus; Systemic Lupus Erythematosus
Interventions: Drug: AMG811; Drug: AMG811 Placebo
Sponsors: Amgen; Amgen
Recruiting - verified March 2012 - Conditions: Pulmonary Arterial Hypertension; HIV Infection; Congenital Heart Defect; Systemic Sclerosis; Connective Tissue Disease
Interventions: Procedure: skin biopsy; Other: Blood Sample
Sponsors: Assistance Publique - Hôpitaux de Paris; Assistance Publique - Hôpitaux de Paris
Recruiting - verified August 2011 - Condition: Cutaneous Lupus Erythematosus
Intervention: Other: Daylong products
Sponsors: Spirig Pharma Ltd.; Spirig Pharma Ltd.
Recruiting - verified June 2011 - Condition: Systemic Lupus Erythematosus
Interventions: Drug: Azathioprine; Drug: Enteric-Coated Mycophenolate Sodium
Sponsors: Hospital Universitari Vall d'Hebron Research Institute; Hospital Universitari Vall d'Hebron Research Institute
Recruiting - verified March 2012 - Condition: SLE
Intervention: Drug: MEDI-570
Sponsors: MedImmune LLC; MedImmune LLC; AstraZeneca
Recruiting - verified January 2012 - Condition: Lupus Arthritis
Interventions: Drug: Laquinimod; Drug: Laquinimod; Other: Placebo
Sponsors: Teva Pharmaceutical Industries; Teva Pharmaceutical Industries
Recruiting - verified May 2012 - Conditions: Immune System Diseases; Autoimmune Diseases; Lupus Erythematosus, Systemic; Skin and Connective Tissue Diseases; Connective Tissue Disease
Interventions: Biological: CDP7657; Other: Placebo
Sponsors: UCB, Inc.; UCB, Inc.
Recruiting - verified May 2012 - Condition: Systemic Lupus Erythematosus
Intervention:
Sponsors: North Shore Long Island Jewish Health System; North Shore Long Island Jewish Health System; National Institute of Allergy and Infectious Diseases (NIAID)
Recruiting - verified January 2012 - Conditions: Lupus Erythematosus, Systemic; Adverse Effects
Interventions: Genetic: Polymorphism Analysis; Drug: Cyclophosphamide; Other: Pharmacokinetic analysis
Sponsors: Sun Yat-sen University; Sun Yat-sen University; First Affiliated Hospital, Sun Yat-Sen University
Recruiting - verified September 2011 - Condition: Lupus Nephritis
Interventions: Drug: Tacrolimus+mycophenolate mofetil; Drug: Azathioprine
Sponsors: Nanjing University School of Medicine; Zhi-Hong Liu, M.D.
Recruiting - verified February 2012 - Condition: Lupus Nephritis
Interventions: Drug: mycophenolate mofetil (MMF); Drug: Tacrolimus (FK506)
Sponsors: Nanjing University School of Medicine; Zhi-Hong Liu, M.D.
Recruiting - verified February 2012 - Conditions: Systemic Lupus Erythematosus; Systemic Sclerosis
Intervention: Procedure: Nonmyeloablative allogeneic stem cell transplant
Sponsors: Duke University; Duke University
Recruiting - verified February 2012 - Conditions: Juvenile Idiopathic Arthritis; Systemic Lupus Erythematosus; Juvenile Dermatomyositis
Intervention: Drug: Human papilloma virus vaccine (cervarix)
Sponsors: UMC Utrecht; N.M. Wulffraat; National Institute for Public Health and the Environment (RIVM)
Recruiting - verified August 2011 - Conditions: Lupus; Nephritis; Systemic Lupus Erythematosus
Intervention: Drug: AMG 811
Sponsors: Amgen; Amgen
Recruiting - verified April 2012 - Condition: Systemic Lupus Erythematosus (SLE)
Intervention: Drug: Rapamycin
Sponsors: State University of New York - Upstate Medical University; State University of New York - Upstate Medical University; Pfizer
Recruiting - verified July 2011 - Condition: Systemic Lupus Erythematosus
Interventions: Drug: N-acetylcysteine; Drug: N-acetylcysteine; Drug: Placebo
Sponsors: State University of New York - Upstate Medical University; State University of New York - Upstate Medical University
Recruiting - verified January 2012 - Condition: Systemic Lupus Erythematosus
Intervention: Drug: AMG 557
Sponsors: Amgen; Amgen
Recruiting - verified August 2011 - Conditions: Lupus Nephritis; Lupus Erythematosus, Systemic
Interventions: Drug: Abatacept; Drug: cyclophosphamide; Drug: azathioprine; Drug: prednisone; Drug: abatacept placebo; Drug: azathioprine placebo
Sponsors: National Institute of Allergy and Infectious Diseases (NIAID); National Institute of Allergy and Infectious Diseases (NIAID); Immune Tolerance Network (ITN)
Recruiting - verified November 2011 - Condition: Systemic Lupus Erythematosus
Intervention:
Sponsors: Medical University of South Carolina; Medical University of South Carolina; National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Recruiting - verified August 2011 - Condition: Systemic Lupus Erythematosus
Intervention: Procedure: Immunoablation and Autologous Hematopoietic Stem Cell Transplantation
Sponsors: Charite University, Berlin, Germany; Charite University, Berlin, Germany
Recruiting - verified August 2009 - Condition: Lupus Erythematosus, Systemic
Intervention: Drug: SBI-087
Sponsors: Pfizer; Pfizer; Emergent Product Development Seattle LLC
Recruiting - verified April 2012 - Conditions: Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Systemic
Intervention: Procedure: laboratory analysis
Sponsors: Kuhn, Annegret; Kuhn, Annegret
Recruiting - verified June 2011 - Conditions: Autoimmune Pancytopenia; Autoimmune Lymphoproliferative Syndrome (ALPS); Evans Syndrome; Idiopathic Thrombocytopenic Purpura; Anemia, Hemolytic, Autoimmune; Autoimmune Neutropenia; Lupus Erythematosus, Systemic; Inflammatory Bowel Disease; Rheumatoid Arthritis
Intervention: Drug: sirolimus
Sponsors: Children's Hospital of Philadelphia; Children's Hospital of Philadelphia
Recruiting - verified May 2012 - Condition: Lupus Nephritis
Interventions: Drug: tacrolimus; Drug: mycophenolate mofetil
Sponsors: Tuen Mun Hospital; Tuen Mun Hospital
Recruiting - verified October 2011 - Condition: Systemic Lupus Erythematosus
Intervention: Biological: Stem Cell Transplantation
Sponsors: Northwestern University; Richard Burt, MD
Recruiting - verified April 2012 - Condition: Systemic Lupus Erythematosus
Intervention: Biological: Hematopoietic stem cell transplantation
Sponsors: Northwestern University; Richard Burt, MD
Recruiting - verified April 2012 - Conditions: Systemic Lupus Erythematosus; Antiphospholipid Syndrome
Intervention:
Sponsors: Hospital for Special Surgery, New York; Hospital for Special Surgery, New York; National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Recruiting - verified December 2011 - Condition: Systemic Lupus Erythematosus
Intervention: Drug: Triptorelin pamoate
Sponsors: FDA Office of Orphan Products Development; FDA Office of Orphan Products Development; Watson Pharmaceuticals
Recruiting - verified August 2011 - Conditions: Rheumatic Diseases; Rheumatoid Arthritis; Systemic Lupus Erythematosus; Scleroderma; Dermatomyositis; Myositis
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Environmental Health Sciences (NIEHS)
Recruiting - verified November 2011 - Conditions: Glomerulonephritis; Lupus Nephritis; Membranous Glomerulonephritis; Nephritis; Nephrotic Syndrome
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified July 2011 - Conditions: Lupus Nephritis; Systemic Lupus Erythematosus
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Recruiting - verified January 2012
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