Clinical Trials for Communication Disorders, Acoustic Neuroma

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Phase II Study of Everolimus (RAD001) in Children and Adults With Neurofibromatosis Type 2

Condition: Neurofibromatosis Type II
Intervention: Drug: Everolimus (RAD001) , Afinitor®
Sponsors: New York University School of Medicine; New York University School of Medicine; Novartis Pharmaceuticals; The Children's Tumor Foundation
Recruiting - verified January 2012
Study of RAD001 for Treatment of NF2-related Vestibular Schwannoma

Conditions: Neurofibromatosis Type 2; Neuroma, Acoustic
Intervention: Drug: RAD001, everolimus
Sponsors: House Research Institute; House Research Institute; Novartis Pharmaceuticals
Not yet recruiting - verified January 2012
Using Positron Emission Tomography to Predict Intracranial Tumor Growth in Neurofibromatosis Type II Patients

Conditions: Neoplasms; Nervous System Disease; Vestibular Disease
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified May 2012
Hearing Outcomes Using Fractionated Proton Radiation Therapy for Vestibular Schwannoma

Conditions: Vestibular Schwannoma; Acoustic Neuroma
Intervention: Radiation: Fractionated proton radiation
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; National Cancer Institute (NCI)
Recruiting - verified May 2012
Bevacizumab in Treating Patients With Recurrent or Progressive Meningiomas

Conditions: Acoustic Schwannoma; Adult Anaplastic Meningioma; Adult Ependymoma; Adult Grade I Meningioma; Adult Grade II Meningioma; Adult Meningeal Hemangiopericytoma; Adult Papillary Meningioma; Neurofibromatosis Type 1; Neurofibromatosis Type 2; Recurrent Adult Brain Tumor
Intervention: Biological: bevacizumab
Sponsors: Northwestern University; Northwestern University
Recruiting - verified May 2012
Intraarterial Cerebral Infusion of Avastin for Vestibular Schwannoma (Acoustic Neuroma)

Condition: Vestibular Schwannoma
Intervention: Drug: Bevacizumab (Avastin)
Sponsors: Weill Medical College of Cornell University; Weill Medical College of Cornell University
Recruiting - verified September 2011
Subtotal Resection of Large Acoustic Neuromas With Possible Stereotactic Radiation Therapy

Condition: Neuroma, Acoustic
Interventions: Procedure: Microsurgery; Procedure: Stereotactic radiation therapy
Sponsors: Stanford University; Stanford University; University of Cincinnati; Baylor College of Medicine; Weill Medical College of Cornell University; University of Iowa; University of Texas; George Washington University
Recruiting - verified March 2012
Concentration and Activity of Lapatinib in Vestibular Schwannomas

Conditions: Vestibular Schwannoma; NF2; Neurofibromatosis 2; Acoustic Neuroma; Auditory Tumor
Intervention: Drug: lapatinib
Sponsors: Sidney Kimmel Comprehensive Cancer Center; Sidney Kimmel Comprehensive Cancer Center; The Children's Tumor Foundation; GlaxoSmithKline; New York University; Ohio State University; House Ear Institute
Recruiting - verified January 2012
Natural History Study of Patients With Neurofibromatosis Type 2

Conditions: Spinal Cord Disease; Intracranial Central Nervous System Disorder; Neurologic Disorders; Brain Neoplasms
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified November 2011