- Condition: X-linked Adrenoleukodystrophy
Intervention: Behavioral: exercise training
Sponsors: Hugo W. Moser Research Institute at Kennedy Krieger, Inc.; Hugo W. Moser Research Institute at Kennedy Krieger, Inc.; European Leukodystrophy Association
Recruiting - verified May 2012 - Conditions: Mucopolysaccharidosis I; Mucopolysaccharidosis VI; Adrenoleukodystrophy; Niemann-Pick Disease; Metachromatic Leukodystrophy; Wolman Disease; Krabbe's Disease; Gaucher's Disease; Fucosidosis; Batten Disease; Severe Aplastic Anemia; Diamond-Blackfan Anemia; Amegakaryocytic Thrombocytopenia; Myelodysplastic Syndrome; Acute Myelogenous Leukemia; Acute Lymphocytic Leukemia
Intervention: Drug: Human Placental Derived Stem Cell
Sponsors: New York Medical College; New York Medical College
Not yet recruiting - verified April 2012 - Condition: Cushing's Disease
Intervention: Drug: Pasireotide sub-cutaneous formulation
Sponsors: Novartis; Novartis Pharmaceuticals
Available - verified April 2012 - Condition: Primary Hyperaldosteronism
Intervention: Procedure: 11C-Metomidate Positron Emission Tomography
Sponsors: Helsinki University Central Hospital; Helsinki University Central Hospital; Turku University Hospital; University of Tampere
Recruiting - verified March 2012 - Conditions: Blood, Injection, Injury Type Phobia; Gastrointestinal Ulcer Haemorrhage; Adverse Reaction to Epinephrine
Interventions: Drug: Epinephrine; Biological: Blood
Sponsors: Zagazig University; Zagazig University
Recruiting - verified March 2012 - Condition: Adrenal Insufficiency
Intervention: Drug: Hydrocortisone
Sponsors: University Medical Centre Groningen; University Medical Centre Groningen
Recruiting - verified March 2012 - Condition: Asthma
Interventions: Drug: corticosteroid nasal spray; Drug: placebo nasal spray
Sponsors: St. Olavs Hospital; St. Olavs Hospital; Norwegian University of Science and Technology
Recruiting - verified March 2012 - Condition: Neuropathic Pain
Intervention:
Sponsors: University Hospital, Clermont-Ferrand; University Hospital, Clermont-Ferrand; Pharmacologic center of the Hospital of Clermont-Ferrand
Not yet recruiting - verified February 2012 - Condition: Renal Insufficiency, Chronic
Interventions: Drug: Mepivacaine with epinephrine; Drug: Plain mepivacaine
Sponsors: Rigshospitalet, Denmark; Rigshospitalet, Denmark
Not yet recruiting - verified March 2012 - Condition: Adrenocortical Carcinoma
Intervention: Drug: Dovitinib
Sponsors: Spanish Oncology Genito-Urinary Group; Spanish Oncology Genito-Urinary Group
Not yet recruiting - verified January 2012 - Conditions: Adrenal Hyperplasia, Congenital; Congenital Hypothyroidism; Cystic Fibrosis
Intervention:
Sponsors: Luminex Molecular Diagnostics; Luminex Corporation
Recruiting - verified January 2012 - Condition: Adrenomyeloneuropathy
Interventions: Drug: N-acetylcysteine; Drug: lipoic acid; Drug: vitamin E
Sponsors: Onofre, Aurora Pujol, M.D.; Onofre, Aurora Pujol, M.D.; Ministerio de Sanidad, Politica Social e Igualdad; Fundacion Hesperia
Recruiting - verified May 2012 - Condition: 21-hydroxylase Deficiency
Intervention: Drug: Abiraterone acetate
Sponsors: Johnson & Johnson Pharmaceutical Research & Development, L.L.C.; Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Recruiting - verified April 2012 - Conditions: Cushing's Syndrome; Adrenal Incidentalomas; Alcoholism; Obesity
Intervention:
Sponsors: Haukeland University Hospital; Haukeland University Hospital
Recruiting - verified May 2012 - Condition: Hemorrhagic Fever With Renal Syndrome
Intervention: Biological: Vaccine/device combination for prevention of HFRS
Sponsors: U.S. Army Medical Research and Materiel Command; U.S. Army Medical Research and Materiel Command; United States Army Medical Research Institute of Infectious Diseases; United States Army Medical Materiel Development Activity; Ichor Medical Systems Incorporated; Walter Reed Army Institute of Research (WRAIR)
Recruiting - verified March 2012 - Condition: Pituitary Neoplasm
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified August 2011 - Conditions: Addison's Disease; Adrenal Insufficiency; Diabetes Mellitus Type I
Intervention: Procedure: Spiroergometry
Sponsors: University of Wuerzburg; University of Wuerzburg
Recruiting - verified October 2011 - Condition: Primary Adrenal Insufficiency
Interventions: Drug: Hydrocortisone intramuscular first; Drug: Hydrocortisone subcutaneously first
Sponsors: University of Wuerzburg; Bruno Allolio
Not yet recruiting - verified October 2011 - Condition: Asthma
Intervention: Drug: Epinephrine Inhalation Aerosol
Sponsors: Amphastar Pharmaceuticals, Inc.; Amphastar Pharmaceuticals, Inc.
Recruiting - verified October 2011 - Condition: Adrenal Insufficiency
Interventions: Procedure: ACTH stimulation test; Procedure: 250 ug ACTH stimulation test; Procedure: 25 ug Cortrosyn stimulation test; Procedure: Insulin tolerance test; Procedure: 1 ug cortrosyn test
Sponsors: The Cleveland Clinic; The Cleveland Clinic
Recruiting - verified March 2012 - Condition: Rheumatoid Arthritis
Intervention: Other: No intervention
Sponsors: Rigshospitalet, Denmark; Rigshospitalet, Denmark
Recruiting - verified April 2012 - Conditions: Obesity; Hyperandrogenemia; Polycystic Ovary Syndrome
Interventions: Drug: Spironolactone; Drug: Dexamethasone; Drug: Cosyntropin; Drug: r-hCG (Ovidrel)
Sponsors: University of Virginia; University of Virginia
Not yet recruiting - verified August 2011 - Conditions: Obesity; Hyperandrogenemia; Polycystic Ovary Syndrome
Interventions: Drug: Metformin; Drug: Dexamethasone; Drug: Cosyntropin; Drug: r-hCG (Ovidrel)
Sponsors: University of Virginia; University of Virginia
Not yet recruiting - verified August 2011 - Conditions: Hyperandrogenemia; Obesity; Polycystic Ovary Syndrome
Interventions: Drug: Hydrocortisone; Drug: dexamethasone; Drug: Cosyntropin; Drug: r-hCG (Ovidrel)
Sponsors: University of Virginia; University of Virginia
Not yet recruiting - verified August 2011 - Conditions: Hyperandrogenemia; Polycystic Ovary Syndrome; Obesity
Interventions: Drug: Dexamethasone; Drug: Cortrosyn
Sponsors: University of Virginia; University of Virginia; Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); University of California, San Diego
Recruiting - verified August 2011 - Conditions: Hyperandrogenemia; Obesity; Polycystic Ovary Syndrome
Interventions: Drug: Hydrocortisone; Drug: dexamethasone; Drug: Cosyntropin (ACTH)
Sponsors: University of Virginia; University of Virginia
Not yet recruiting - verified August 2011 - Conditions: Gastro-enteropancreatic Neuroendocrine Tumor; Secondary Malignant Neoplasm of Liver
Intervention: Other: magnetic resonance imaging (MRI)
Sponsors: Memorial Sloan-Kettering Cancer Center; Memorial Sloan-Kettering Cancer Center
Recruiting - verified December 2011 - Condition: Cushing's Disease
Interventions: Drug: SOM230 LAR 30 mg; Drug: SOM230 LAR 10 mg
Sponsors: Novartis; Novartis Pharmaceuticals
Recruiting - verified May 2012 - Condition: Uterine Cervical Dysplasia
Intervention: Drug: sodium bicarbonate buffered lidocaine
Sponsors: Washington University School of Medicine; Washington University School of Medicine
Recruiting - verified October 2011 - Condition: Cushing Syndrome
Intervention: Procedure: surgery
Sponsors: Samsung Medical Center; Samsung Medical Center; Asan Medical Center; Severance Hospital; Konkuk University Medical Center
Recruiting - verified June 2011 - Conditions: Hematological Malignancies; Certain Lysosomal Storage and Peroxisomal Enzyme Deficiency Disorders; Hurler Syndrome (MPS I); Krabbe Disease (Globoid Leukodystrophy); X-linked Adrenoleukodystrophy; Primary Immunodeficiency Diseases; Bone Marrow Failure; Beta-thalassemia
Intervention: Drug: A multicenter access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs)
Sponsors: Center for International Blood and Marrow Transplant Research; Center for International Blood and Marrow Transplant Research; National Marrow Donor Program
Recruiting - verified April 2012 - Condition: Adrenal Gland Neoplasms
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Cancer Institute (NCI)
Recruiting - verified January 2012 - Condition: Cushing Disease
Intervention: Drug: LCI699
Sponsors: Novartis; Novartis Pharmaceuticals
Recruiting - verified May 2012 - Study Comparing the Efficacy and Tolerability of Epinephrine and Norepinephrine in Cardiogenic ShockCondition: Cardiogenic Shock
Intervention: Drug: epinephrine/norepinephrine
Sponsors: Central Hospital, Nancy, France; Central Hospital, Nancy, France
Recruiting - verified June 2011 - Conditions: Adrenal Hyperplasia; Polycystic Ovarian Syndrome; Oligomenorrhea; Obesity; Hyperandrogenism
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - verified January 2012 - Condition: Adrenal Failure
Intervention: Drug: depot tetracosactide
Sponsors: Newcastle University; Newcastle University
Recruiting - verified June 2011 - Condition: Anorexia Nervosa (AN)
Interventions: Drug: DHEA (Prasterone) + ERT (Aviane); Other: Placebo
Sponsors: Children's Hospital Boston; Children's Hospital Boston
Recruiting - verified May 2012 - Conditions: Adult Growth Hormone Deficiency; Hypothalamic-pituitary Disorders
Interventions: Procedure: Glucagon stimulation test and insulin tolerance test; Procedure: glucagon stimulation test and insulin tolerance test
Sponsors: The Cleveland Clinic; The Cleveland Clinic; Massachusetts General Hospital; Allegheny Endocrinology Associates; Oregon Health and Science University
Recruiting - verified January 2011 - Condition: Adrenal Cortex Neoplasms
Intervention: Drug: Axitinib
Sponsors: National Institutes of Health Clinical Center (CC); National Cancer Institute (NCI); Pfizer Pharmaceuticals, Inc.
Recruiting - verified July 2011 - Condition: Adrenal Tumour With Mild Hypercortisolism
Intervention: Procedure: Adrenalectomy
Sponsors: Region Skane; Region Skane
Recruiting - verified January 2012 - Condition: Aortic Stiffness is a Predictor of Blood Pressure Response After Surgery in Patients With Aldosterone Producing Adenoma.
Intervention: Device: complier device
Sponsors: University Hospital, Toulouse; University Hospital, Toulouse
Recruiting - verified March 2012 - Conditions: Non-Small-Cell Lung Carcinoma; Liver Cancer; Adrenal Cancer
Intervention: Radiation: stereotactic body radiation therapy
Sponsors: Wake Forest University; Wake Forest University
Recruiting - verified October 2011 - Conditions: Traumatic Brain Injury; Trauma; Adrenal Insufficiency; Pneumonia
Interventions: Drug: Placebo; Drug: Hydrocortisone Fludrocortisone; Other: No treatment
Sponsors: Nantes University Hospital; Nantes University Hospital; Société Française d'Anesthésie et de Réanimation (SFAR)
Recruiting - verified December 2011 - Conditions: Breast Cancer; Lung Cancer; Renal Cancer; Adrenal Cancer
Intervention: Drug: F-18 Paclitaxel (FPAC)
Sponsors: National Institutes of Health Clinical Center (CC); National Cancer Institute (NCI)
Not yet recruiting - verified September 2011 - Conditions: Mucopolysaccharidosis; Hurler Syndrome; Hunter Syndrome; Maroteaux-Lamy Syndrome; Sly Syndrome; Alpha Mannosidosis; Fucosidosis; Aspartylglucosaminuria; Adrenoleukodystrophy (ALD); Globoid Cell Leukodystrophy (GLD); Krabbe Disease; Metachromatic Leukodystrophy (MLD); Sphingolipidoses; Peroxisomal Disorders
Interventions: Drug: Campath-1H; Drug: Cyclophosphamide; Drug: Busulfan; Procedure: Allogeneic stem cell transplantation
Sponsors: Masonic Cancer Center, University of Minnesota; Masonic Cancer Center, University of Minnesota
Recruiting - verified April 2012 - Conditions: Neuroendocrine Neoplasms; Thyroid Neoplasms; Parathyroid Neoplasms; Adrenal Neoplasm; Neuroblastoma
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Cancer Institute (NCI)
Recruiting - verified June 2011 - Conditions: Pancreatic Neoplasm; Pituitary Neoplasm; Nelson Syndrome; Ectopic ACTH Syndrome
Intervention: Drug: Pasireotide LAR
Sponsors: Novartis; Novartis Pharmaceuticals
Recruiting - verified November 2011 - Conditions: Pituitary Adenomas; Prolactinomas; Cushing's Disease
Intervention: Drug: Lapatinib
Sponsors: Cedars-Sinai Medical Center; Cedars-Sinai Medical Center
Recruiting - verified November 2011 - Condition: Adrenal Tumors
Intervention:
Sponsors: Kliniken Essen-Mitte; Kliniken Essen-Mitte
Recruiting - verified May 2009 - Condition: Cushing's Disease
Intervention: Drug: Bexarotene
Sponsors: University of Virginia; University of Virginia
Recruiting - verified May 2011 - Condition: Adrenocortical Tumor
Intervention:
Sponsors: St. Jude Children's Research Hospital; St. Jude Children's Research Hospital
Recruiting - verified April 2012 - Conditions: Cushing's Syndrome; Insulin Resistance
Intervention: Procedure: Surgery
Sponsors: University of Aarhus; University of Aarhus; Aarhus University Hospital
Recruiting - verified March 2012 - Conditions: Adrenal Cortical Cancer; Brain Cancer; Breast Cancer; CNS Cancer; Colon Cancer; HEENT Cancer; Hodgkin's Disease; Kaposi's Sarcoma; Liver Cancer; Lung Cancer; Non-Hodgkin's Lymphoma; Ovarian Cancer; Pancreatic Cancer; Prostate Cancer; Rectal Cancer; Renal Cancer; Sarcoma; Squamous Cell Carcinoma; Thyroid Cancer
Interventions: Device: Proton-decoupled 31P MRS at 1.5T; Device: 1H Spectroscopy at 1.5T and 3T
Sponsors: Memorial Sloan-Kettering Cancer Center; Memorial Sloan-Kettering Cancer Center; Columbia University; University of Pennsylvania; St.George's Hospital (England); Royal Marsden NHS Foundation Trust; University Medical Center Nijmegen; Weill Medical College of Cornell University
Recruiting - verified February 2012 - Condition: Malnourished Children With Cancer
Interventions: Drug: Megstrol Acetate; Other: Placebo
Sponsors: University of British Columbia; University of British Columbia; University of Alberta
Recruiting - verified October 2011 - Conditions: Adrenoleukodystrophy; Metachromatic Leukodystrophy; Globoid Cell Leukodystrophy; Tay Sachs Disease; Sandhoffs Disease; Wolman Disease; I-Cell Disease; Sanfilippo Syndrome; GM1 Gangliosidosis
Interventions: Drug: Clofarabine; Procedure: Total body Irradiation; Drug: Melphalan
Sponsors: Masonic Cancer Center, University of Minnesota; Masonic Cancer Center, University of Minnesota
Recruiting - verified October 2011 - Condition: Adrenocortical Carcinoma
Interventions: Biological: filgrastim; Biological: pegfilgrastim; Drug: cisplatin; Drug: doxorubicin hydrochloride; Drug: etoposide; Drug: mitotane; Procedure: conventional surgery
Sponsors: National Cancer Institute (NCI); Children's Oncology Group; National Cancer Institute (NCI)
Recruiting - verified July 2011 - Conditions: Excess Androgen; Congenital Adrenal Hyperplasia (CAH); Familial Male-Limited Precocious Puberty (FMPP)
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - verified March 2012 - Condition: Adrenal Insufficiency
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - verified March 2012 - Condition: Adrenal Gland Neoplasm
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - verified September 2011 - Condition: Pheochromocytoma
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - verified June 2011 - Conditions: Autoimmune Disease; Congenital Adrenal Hyperplasia; Healthy; Mental Disorder Diagnosed in Childhood; Neurologic Manifestations
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Mental Health (NIMH)
Recruiting - verified September 2011 - Conditions: Cushing's Syndrome; Hereditary Neoplastic Syndrome; Lentigo; Neoplasm; Testicular Neoplasm
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - verified June 2011 - Conditions: Abnormalities; Craniopharyngioma; Cushing's Syndrome; Endocrine Disease; Pituitary Neoplasm
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - verified June 2011 - Conditions: Amenorrhea; Hypoaldosteronism; Hypogonadism; Infertility; Premature Ovarian Failure
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - verified December 2011 - Condition: Cushing Syndrome
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - verified September 2011
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