- Condition: Postoperative Pain
Interventions: Drug: Acetaminophen; Drug: Placebo
Sponsors: The University of Texas Health Science Center, Houston; The University of Texas Health Science Center, Houston; Cadence Pharmaceuticals
Not yet recruiting - verified May 2012 - Condition: Chronic Pain
Interventions: Device: SR-electrical stimulation (Bioness); Device: Sham ES and pain medication during first 3 months (Bioness)
Sponsors: Bioness Inc; Bioness Inc
Recruiting - verified May 2012 - Conditions: Cannabis Dependence; Marijuana Dependence
Interventions: Drug: Dronabinol; Drug: Clonidine; Drug: Placebo
Sponsors: Mclean Hospital; Mclean Hospital; Brain and Behavior Research Foundation (formerly NARSAD)
Recruiting - verified May 2012 - Condition: Psoriasis
Interventions: Drug: 80 mg ixekizumab Dosing Regimen; Drug: 50 mg etanercept; Drug: Placebo
Sponsors: Eli Lilly and Company; Eli Lilly and Company
Not yet recruiting - verified May 2012 - Condition: Labor Pain
Intervention: Drug: Hydromorphone
Sponsors: Emory University; Emory University
Not yet recruiting - verified May 2012 - Condition: Chest Pain
Interventions: Drug: Marinol; Drug: Placebo
Sponsors: University of Iowa; University of Iowa
Recruiting - verified May 2012 - Conditions: Atrial Fibrillation; Electrical Cardioversion
Interventions: Drug: Magnesium Sulfate; Other: Placebo
Sponsors: State University of New York at Buffalo; State University of New York at Buffalo
Recruiting - verified May 2012 - Condition: Depression
Intervention: Dietary Supplement: Magnesium sulfate
Sponsors: University of Miami; University of Miami; Life Extension Foundation
Recruiting - verified May 2012 - Condition: Fibromyalgia
Interventions: Drug: Tramadol; Drug: Placebo; Behavioral: Cognitive Behavior Therapy for FM; Behavioral: Health Education
Sponsors: University of Washington; University of Washington
Not yet recruiting - verified May 2012 - Condition: Metastatic Castration-resistant Prostate Cancer
Interventions: Drug: Cabazitaxel; Drug: Mitoxantrone; Drug: Prednisone; Drug: Pegfilgrastim
Sponsors: University of California, San Francisco; Andrea Harzstark; Sanofi-Aventis
Not yet recruiting - verified May 2012 - Conditions: Chronic Pain; Opioid Addiction
Interventions: Other: Yoga; Behavioral: Educational Counseling
Sponsors: Yale University; Yale University
Recruiting - verified April 2012 - Condition: Myelodysplastic Syndrome
Interventions: Drug: Decitabine; Drug: Vorinostat; Biological: Interleukin-2; Other: Natural killer (NK) cells
Sponsors: Masonic Cancer Center, University of Minnesota; Masonic Cancer Center, University of Minnesota
Not yet recruiting - verified May 2012 - Condition: Impaired Glucose Tolerance
Interventions: Dietary Supplement: Resveratrol; Dietary Supplement: resveratrol /HMB; Other: Placebo treatment
Sponsors: Vanderbilt University; Vanderbilt University; Nutraceutical Discoveries, Inc.
Recruiting - verified May 2012 - Condition: Coronary Artery Disease
Interventions: Device: PROMUS Element Plus Coronary Stent System; Drug: Aspirin; Drug: P2Y12 antagonist
Sponsors: Boston Scientific Corporation; Boston Scientific Corporation
Not yet recruiting - verified May 2012 - Condition: Acute Low Back Pain
Interventions: Drug: Naproxen; Drug: Cyclobenzaprine; Drug: Oxycodone/ acetaminophen
Sponsors: Montefiore Medical Center; Montefiore Medical Center
Recruiting - verified April 2012 - Condition: Neuroblastoma
Interventions: Biological: ch14.18 -NCI; Biological: ch14.18-UTC; Biological: Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF); Biological: Aldesleukin (IL-2); Drug: Isotretinoin
Sponsors: United Therapeutics; United Therapeutics
Not yet recruiting - verified May 2012 - Conditions: Abdominal Muscles/Ultrasonography; Adult; Anesthetics, Local/Administration & Dosage; Ropivacaine/Administration & Dosage; Ropivacaine/Analogs & Derivatives; Cesarean Section; Humans; Nerve Block/Methods; Pain Measurement/Methods; Pain, Postoperative/Prevention & Control; Ultrasonography, Interventional
Interventions: Device: TAP catheter; Drug: intrathecal morphine
Sponsors: Stamford Anesthesiology Services, PC; Stamford Anesthesiology Services, PC; I-Flow
Recruiting - verified May 2012 - Condition: Obesity
Intervention: Drug: Propofol, Fentanyl
Sponsors: Stanford University; Stanford University; National Institute of General Medical Sciences (NIGMS)
Recruiting - verified May 2012 - Condition: Bioequivalence
Interventions: Drug: Flector patch; Device: Microdialysis probe
Sponsors: University of Florida; University of Florida; Food and Drug Administration (FDA)
Recruiting - verified May 2012 - Conditions: Sarcoma; Solid Tumors; Pulmonary Metastases; Lung Metastases; Osteosarcomas; Ewing Sarcoma
Interventions: Drug: Aerosol IL-2; Procedure: Symptom Assessment
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center; Shannon Wilkes Foundation
Not yet recruiting - verified May 2012 - Conditions: Asthma, Aspirin-Induced; Aspirin Exacerbated Asthma
Intervention: Drug: Prasugrel
Sponsors: Brigham and Women's Hospital; Elliot Israel, MD; Brigham and Women's Hospital
Not yet recruiting - verified May 2012 - Conditions: Back Pain; Osteoarthritis
Interventions: Other: Opioid-intensive prescribing strategy; Other: Opioid-avoidant prescribing strategy
Sponsors: Department of Veterans Affairs; Department of Veterans Affairs
Not yet recruiting - verified April 2012 - Condition: Atrial Fibrillation Ablation
Intervention: Drug: Adenosine arm
Sponsors: Medical College of Wisconsin; Medical College of Wisconsin
Not yet recruiting - verified May 2012 - Conditions: Regional Block for Pain Control; Supraclavicular Block; Ultrasound Guided Block; Block Additive
Intervention: Drug: Buprenorphine
Sponsors: University of Wisconsin, Madison; University of Wisconsin, Madison
Recruiting - verified April 2012 - Conditions: Ulcerative Colitis; Left-sided Ulcerative Colitis; Distal Ulcerative Colitis
Interventions: Drug: Zoenasa-1:4; Drug: Mesalamine Enema
Sponsors: Altheus Therapeutics, Inc.; Altheus Therapeutics, Inc.
Not yet recruiting - verified April 2012 - Condition: Healthy
Interventions: Drug: Naloxone; Drug: Delta-9-THC; Drug: Placebo
Sponsors: Yale University; Yale University
Recruiting - verified May 2012 - Conditions: Fabry Disease; Neuropathic Pain
Interventions: Drug: Gabapentin; Drug: placebo
Sponsors: University of Minnesota - Clinical and Translational Science Institute; University of Minnesota - Clinical and Translational Science Institute; Genzyme
Recruiting - verified April 2012 - Condition: Pain
Interventions: Drug: fentanyl; Drug: fentanyl, sufentanil
Sponsors: Pacira Pharmaceuticals, Inc; Pacira Pharmaceuticals, Inc
Recruiting - verified April 2012 - Condition: Breast Augmentation
Interventions: Drug: Morphine Sulfate; Drug: morphine sulfate, hydromorphone HCl
Sponsors: Pacira Pharmaceuticals, Inc; Pacira Pharmaceuticals, Inc
Recruiting - verified May 2012 - Conditions: Pharmacokinetics of Isavuconazole; Pharmacokinetics of Methadone; Healthy Volunteers
Interventions: Drug: Isavuconazole; Drug: Methadone
Sponsors: Astellas Pharma Inc; Astellas Pharma Global Development, Inc.; Basilea Pharmaceutica International Ltd
Recruiting - verified April 2012 - Condition: Diabetic Neuropathic Pain
Interventions: Drug: ABT-652 6 mg; Drug: ABT-652 12 mg; Drug: ABT-652 12 mg - 18 mg; Drug: Placebo comparator; Drug: Duloxetine
Sponsors: Abbott; Abbott
Recruiting - verified April 2012 - Condition: Major Depressive Disorder
Intervention: Drug: Ketamine
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified April 2012 - Condition: Brain Tumor
Intervention: Drug: Sulfasalazine
Sponsors: University of Alabama at Birmingham; University of Alabama at Birmingham
Recruiting - verified April 2012 - Conditions: Schizophrenia; Schizoaffective Disorder
Intervention: Drug: salsalate
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; National Institutes of Health (NIH)
Recruiting - verified April 2012 - Conditions: Ischemic Stroke; Transient Ischemic Attack (TIA)
Intervention: Other: Vitamin E tocotrienol (TCT) pills ; Low dose Aspirin
Sponsors: Ohio State University; Chandan K Sen; Government of Malaysia
Recruiting - verified April 2012 - Condition: Healthy Volunteers
Interventions: Drug: Standard dose BG00012; Drug: Aspirin placebo; Drug: Aspirin; Drug: Escalating doses of BG00012; Drug: BG00012 placebo
Sponsors: Biogen Idec; Biogen Idec
Recruiting - verified April 2012 - Condition: Substance-Related Disorders
Intervention: Drug: naltrexone for extended release injectable suspension
Sponsors: Rhode Island Hospital; Rhode Island Hospital; National Institute on Drug Abuse (NIDA); Alkermes
Recruiting - verified March 2012 - Condition: Chronic Pain
Intervention:
Sponsors: Brigham and Women's Hospital; Brigham and Women's Hospital
Recruiting - verified March 2012 - Conditions: Post-anesthesia Recovery; Orientation
Interventions: Drug: Ketamine; Drug: Methohexital
Sponsors: University of New Mexico; University of New Mexico
Recruiting - verified March 2012 - Condition: Usage of Prescription Opioids
Intervention:
Sponsors: Analgesic Solutions; Analgesic Solutions
Not yet recruiting - verified March 2012 - Condition: Mucositis
Intervention: Drug: Ketamine
Sponsors: West Virginia University; Aaron Cumpston, PharmD
Recruiting - verified March 2012 - Condition: Esophageal Cancer
Interventions: Behavioral: Quality of Life instruments, FACT-E, Symptom Assessment Scale, Brief Pain Inventory and Daily Analgesic Log; Behavioral: Quality of Life instruments, FACT-E, Symptom Assessment Scale, Brief Pain Inventory and Daily Analgesic Log
Sponsors: Memorial Sloan-Kettering Cancer Center; Memorial Sloan-Kettering Cancer Center
Recruiting - verified May 2012 - Condition: Low Back Pain
Interventions: Drug: Methadone; Drug: Buprenorphine/naloxone
Sponsors: State University of New York at Buffalo; State University of New York at Buffalo
Recruiting - verified March 2012 - Condition: Advanced Solid Tumors, Excluding Breast Cancer
Interventions: Drug: caffeine; Drug: diclofenac; Drug: omeprazole; Drug: midazolam; Drug: TKI258
Sponsors: Novartis; Novartis Pharmaceuticals
Not yet recruiting - verified May 2012 - Condition: Subarachnoid Hemorrhage, Aneurysmal
Interventions: Drug: Dexmedetomidine; Drug: propofol
Sponsors: University of Cincinnati; University of Cincinnati
Recruiting - verified March 2012 - Condition: Maternal Opioid Dependency During Pregnancy
Intervention: Drug: Buprenorphine
Sponsors: Johns Hopkins University; Johns Hopkins University
Recruiting - verified March 2012 - Condition: Pain
Interventions: Drug: Ibuprofen/acetaminophen; Drug: Ibuprofen/acetaminophen; Drug: Ibuprofen/acetaminophen; Drug: Ibuprofen; Drug: Placebo
Sponsors: Pfizer; Pfizer
Not yet recruiting - verified April 2012 - Condition: Management of Moderate to Severe Pain
Interventions: Drug: ALO-02; Drug: Naltrexone block; Drug: ALO-02; Drug: Naltrexone block; Drug: OxyContin; Drug: Naltrexone block
Sponsors: Pfizer; Pfizer
Recruiting - verified April 2012 - Conditions: Substance-related Disorders; HIV Risk Behavior
Interventions: Behavioral: Therapeutic Workplace; Drug: Methadone
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute on Drug Abuse (NIDA)
Not yet recruiting - verified March 2012 - Condition: Major Depressive Disorder
Interventions: Drug: Ketamine; Drug: Ketamine; Drug: Ketamine; Drug: Ketamine; Drug: Ketamine; Drug: Saline
Sponsors: Columbia University; Columbia University; National Institute of Mental Health (NIMH)
Recruiting - verified March 2012 - Condition: Headache
Interventions: Drug: BAY1019036; Drug: Acetaminophen; Drug: Placebo
Sponsors: Bayer; Bayer
Recruiting - verified May 2012 - Condition: Opiate Dependence
Interventions: Drug: Vivitrol; Behavioral: Employment based opiate abstinence reinforcement; Other: Usual Care Control
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute on Drug Abuse (NIDA)
Not yet recruiting - verified March 2012 - Condition: Management of Moderate to Severe Pain
Interventions: Drug: Oxycodone; Drug: Oxycodone; Drug: Oxycodone; Drug: Oxycodone; Drug: Oxycodone
Sponsors: Pfizer; Pfizer
Recruiting - verified April 2012 - Condition: Rheumatoid Arthritis
Interventions: Drug: Triple Therapy; Drug: TNF inhibitors
Sponsors: Columbia University; Columbia University; National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Recruiting - verified March 2012 - Conditions: Depression; Alcohol Dependence
Intervention: Drug: Ketalar (ketamine)
Sponsors: Yale University; Yale University; VA Connecticut Healthcare System
Recruiting - verified April 2012 - Condition: General Anesthesia
Intervention: Drug: propofol
Sponsors: Ethicon Endo-Surgery; Ethicon Endo-Surgery
Recruiting - verified March 2012 - Condition: Opioid Dependence
Interventions: Behavioral: Distress Tolerance; Behavioral: Health Education
Sponsors: Butler Hospital; Butler Hospital
Not yet recruiting - verified March 2012 - Condition: Postoperative Pain
Interventions: Drug: Methadone; Drug: Hydromorphone
Sponsors: NorthShore University HealthSystem Research Institute; NorthShore University HealthSystem Research Institute
Recruiting - verified March 2012 - Condition: Hip Fracture
Interventions: Procedure: Femoral Nerve Catheterization; Procedure: Intravenous Opioids
Sponsors: Ochsner Health System; Leslie Thomas; American Society of Anesthesiologists
Recruiting - verified March 2012 - Condition: Preeclampsia
Interventions: Drug: Aspirin; Drug: placebo
Sponsors: Washington University School of Medicine; Washington University School of Medicine
Recruiting - verified March 2012 - Condition: Healthy Controls
Interventions: Radiation: Integrated MR-PET scan; Drug: Ketorolac; Drug: Morphine
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified April 2012 - Condition: Chronic Pain
Interventions: Device: Non Boston Scientific spinal cord stimulation system; Device: Boston Scientific Precision Plus spinal cord stimulation system; Other: Non-spinal cord stimulation conventional medical management for chronic pain
Sponsors: Boston Scientific Corporation; Boston Scientific Corporation
Recruiting - verified March 2012 - Condition: Osteoarthritis, Knee
Interventions: Drug: Naproxen; Drug: Placebo
Sponsors: Analgesic Solutions; Analgesic Solutions
Recruiting - verified February 2012 - Condition: Metastatic Renal Cell Carcinoma
Interventions: Drug: Hydroxychloroquine; Drug: IL-2
Sponsors: University of Pittsburgh; University of Pittsburgh; Prometheus Laboratories
Recruiting - verified March 2012 - Condition: Degenerative Joint Disease of Hip and Knee.
Interventions: Drug: Placebo; Drug: Gapabentin
Sponsors: University of Medicine and Dentistry New Jersey; University of Medicine and Dentistry New Jersey
Recruiting - verified March 2012 - Condition: Other Acute Postoperative Pain
Interventions: Drug: Indomethacin; Drug: Indomethacin; Drug: Indomethacin; Drug: Celecoxib; Drug: Placebo
Sponsors: Iroko Pharmaceuticals, LLC; Iroko Pharmaceuticals, LLC
Recruiting - verified February 2012 - Conditions: Pain; Chronic Pain
Intervention: Drug: iv acetaminophen 1g
Sponsors: University of Washington; University of Washington; Cadence Pharmaceuticals
Not yet recruiting - verified February 2012 - Condition: Back Pain Lower Back Chronic
Interventions: Drug: Saline; Drug: Dextrose
Sponsors: Smigel, Liza, M.D.; Smigel, Liza, M.D.
Recruiting - verified March 2012 - Conditions: Pain, Postoperative; Chronic Pain
Interventions: Drug: Methadone; Drug: Fentanyl
Sponsors: NorthShore University HealthSystem Research Institute; NorthShore University HealthSystem Research Institute
Recruiting - verified February 2012 - Conditions: Acute Liver Failure; Acute Liver Injury
Intervention: Drug: Ornithine phenylacetate
Sponsors: University of Texas Southwestern Medical Center; William Lee; Medical University of South Carolina; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Ocera Therapeutics
Not yet recruiting - verified March 2012 - Condition: Traumatic Rib Fracture
Interventions: Procedure: Paravertebral Block; Procedure: Intercostal Nerve Block
Sponsors: Brigham and Women's Hospital; Brigham and Women's Hospital
Recruiting - verified May 2012 - Condition: Post-Operative Pain
Interventions: Drug: Sufentanil NanoTab PCA System/15 mcg; Drug: Placebo Sufentanil NanoTab PCA System
Sponsors: AcelRx Pharmaceuticals, Inc.; AcelRx Pharmaceuticals, Inc.
Recruiting - verified May 2012 - Condition: Post-Operative Pain
Interventions: Drug: Sufentanil NanoTab PCA System/15 mcg; Drug: morphine IV PCA
Sponsors: AcelRx Pharmaceuticals, Inc.; AcelRx Pharmaceuticals, Inc.
Recruiting - verified April 2012 - Condition: Cardiovascular Disease
Interventions: Dietary Supplement: ResA; Dietary Supplement: Resveratrol; Dietary Supplement: Placebo
Sponsors: University of California, Davis; University of California, Davis; Gateway Health Alliance
Not yet recruiting - verified March 2012 - Conditions: Knee Pain; Knee Chondroplasty
Interventions: Drug: Theramine; Drug: Theramine- like placebo
Sponsors: Targeted Medical Pharma; Targeted Medical Pharma
Not yet recruiting - verified February 2012 - Conditions: Abdomen, Acute; Other Acute Pain; Flank Pain, Acute; Back Pain, Acute; Extremity Pain, Acute
Interventions: Drug: Ketamine; Drug: Morphine
Sponsors: Brooke Army Medical Center; Brooke Army Medical Center; U.S. Air Force Office of the Surgeon General
Recruiting - verified February 2012 - Conditions: Heroin Dependence; Opioid-Related Disorders
Intervention:
Sponsors: Wayne State University; Wayne State University; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Conditions: Opioid Withdrawal; Physical Dependence
Intervention: Drug: Ondansetron
Sponsors: Stanford University; Stanford University; National Institute on Drug Abuse (NIDA)
Recruiting - verified March 2012 - Condition: Ulcerative Colitis
Interventions: Drug: Mesalamine; Drug: Prednisone; Drug: Corticosteroids followed by mesalamine (Pentasa)
Sponsors: Connecticut Children's Medical Center; Connecticut Children's Medical Center; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Not yet recruiting - verified April 2012 - Condition: Drug Induced Constipation
Interventions: Drug: Nektar 118; Drug: Quinidine; Drug: Quinidine placebo; Drug: Morphine
Sponsors: AstraZeneca; AstraZeneca
Recruiting - verified March 2012 - Condition: Hot Flashes in Men With Prostate Cancer Receiving Androgen Ablation Therapy
Interventions: Drug: Gabapentin; Drug: Venlafaxine
Sponsors: University of Wisconsin, Madison; University of Wisconsin, Madison
Recruiting - verified February 2012 - Condition: Fever
Interventions: Drug: Intravenous Ibuprofen; Drug: Acetaminophen (Standard of Care)
Sponsors: Columbia University; Columbia University; Cumberland Pharmaceuticals
Recruiting - verified February 2012 - Conditions: Abscess; Pain
Interventions: Drug: Intranasal Fentanyl; Drug: Intravenous Morphine
Sponsors: Columbia University; Columbia University
Recruiting - verified March 2012 - Condition: Tonsillectomy
Interventions: Drug: Dexmedetomidine; Other: Placebo
Sponsors: Children's Hospital of Pittsburgh; Children's Hospital of Pittsburgh; Hospira, Inc.
Recruiting - verified February 2012 - Condition: Healthy
Interventions: Drug: Lacosamide (LCM); Drug: Carbamazepine Immediate Release (CBZ-IR)
Sponsors: UCB, Inc.; UCB, Inc.
Recruiting - verified May 2012 - Conditions: Hot Flashes; Breast Cancer
Interventions: Drug: solifenacin; Drug: Clonidine
Sponsors: University of Arkansas; University of Arkansas
Recruiting - verified February 2012 - Condition: Epicondylitis of the Elbow
Interventions: Drug: Naproxen; Drug: Synera patch twice daily; Drug: Synera patch for 12hrs/day; Drug: Naproxen; Drug: Synera; Drug: Synera
Sponsors: International Clinical Research Institute; International Clinical Research Institute
Not yet recruiting - verified January 2012 - Condition: Opioid-Related Disorders
Interventions: Drug: Pioglitazone; Drug: Placebo
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified November 2011 - Conditions: Ultrasound; CT Scans; MRIs
Interventions: Drug: Dexmedetomidine; Drug: Midazolam; Drug: Fentanyl
Sponsors: Hospira, Inc.; Hospira, Inc.
Recruiting - verified April 2012 - Condition: Post-Traumatic Stress Disorder
Interventions: Drug: Tramadol; Drug: Placebo
Sponsors: INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium; INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium; U.S. Army Medical Research and Materiel Command
Recruiting - verified January 2012 - Condition: Acne Vulgaris
Interventions: Drug: Epiduo Gel; Drug: Retin-A Micro Microsphere 0.1%
Sponsors: Galderma Laboratories, L.P.; Galderma Laboratories, L.P.
Recruiting - verified March 2012 - Conditions: Pain; Hip Fracture
Interventions: Drug: Placebo; Drug: Acetaminophen IV
Sponsors: Lancaster General Hospital; Lancaster General Hospital
Recruiting - verified January 2012 - Condition: Asthma
Interventions: Drug: Magnesium Sulfate; Drug: Placebo
Sponsors: University of Louisville; University of Louisville
Recruiting - verified January 2012 - Condition: Malignant Neoplasm
Interventions: Drug: placebo administration; Drug: EMLA; Drug: propofol; Drug: fentanyl citrate
Sponsors: Comprehensive Cancer Center of Wake Forest University; Comprehensive Cancer Center of Wake Forest University; National Cancer Institute (NCI)
Recruiting - verified March 2012 - Condition: Myringotomy
Intervention: Drug: Dexmedetomidine
Sponsors: University of Iowa; University of Iowa
Recruiting - verified February 2012 - Condition: Psoriasis
Intervention: Drug: etanercept
Sponsors: Amgen; Amgen
Recruiting - verified April 2012 - Conditions: Advanced Cancers; Dyspnea
Interventions: Drug: Fentanyl; Other: Placebo; Other: Walking Tests; Behavioral: Questionnaires
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center
Recruiting - verified April 2012 - Condition: Diabetes Mellitus, Type 2
Interventions: Drug: PL2200 Aspirin Capsules; Drug: Immediate-Release Aspirin Tablets; Drug: Enteric-coated aspirin caplets
Sponsors: PLx Pharma; PLx Pharma
Recruiting - verified January 2012 - Condition: Schizophrenia
Interventions: Drug: Anti-inflammatory Combination Therapy; Drug: Placebo
Sponsors: University of Maryland; University of Maryland
Not yet recruiting - verified January 2012 - Conditions: Prostate Cancer; Castration Resistant Prostate Cancer; Pain; Prostatic Neoplasms
Interventions: Drug: cabozantinib; Drug: mitoxantrone; Drug: prednisone
Sponsors: Exelixis; Exelixis
Recruiting - verified April 2012 - Condition: Asthma
Intervention: Drug: Nebulized magnesium sulfate
Sponsors: University of Texas Southwestern Medical Center; University of Texas Southwestern Medical Center
Recruiting - verified September 2011 - Conditions: Acute Lymphoblastic Leukemia; Lymphoblastic Lymphoma; Burkitts Leukemia/Lymphoma; Chronic Myelogenous Leukemia
Interventions: Drug: CLAG-M; Drug: CLAG-M
Sponsors: New York Medical College; New York Medical College
Recruiting - verified January 2012 - Conditions: Osteoarthritis of the Knee; Coagulopathy
Intervention: Drug: PENNSAID (diclofenac sodium solution topical)
Sponsors: Arthritis Treatment Center, Maryland; Nathan Wei, MD, FACP, FACR:; Covidien; Arthritis Treatment Center, Maryland
Recruiting - verified February 2012 - Conditions: Chronic Pain; Opioid Abuse, Unspecified Use
Interventions: Behavioral: Mindfulness-Oriented Recovery Enhancement; Behavioral: Conventional Support Group (SG)
Sponsors: Florida State University; Florida State University; National Institute on Drug Abuse (NIDA); Fahs Beck Fund for Research and Experimentation
Recruiting - verified March 2012 - Condition: Rotator Cuff Tear
Interventions: Device: Ivivi Torino II; Device: Inactive Sham device
Sponsors: Amp Orthopedics, Inc.; Amp Orthopedics, Inc.
Recruiting - verified January 2012 - Conditions: Anemia; Unexplained Anemia
Interventions: Drug: Salsalate; Drug: Salsalate placebo
Sponsors: Duke University; Duke University; National Institute on Aging (NIA)
Not yet recruiting - verified January 2012 - Condition: Anesthesia
Interventions: Drug: Midazolam; Drug: Fentanyl; Drug: Morphine
Sponsors: Hospira, Inc.; Hospira, Inc.
Recruiting - verified April 2012 - Condition: Chronic Pain
Intervention: Drug: Hydrocodone
Sponsors: NEMA Research, Inc.; NEMA Research, Inc.; Covidien; International Clinical Research Institute
Recruiting - verified April 2012 - Condition: Suicidal Ideation
Interventions: Drug: Ketamine; Drug: Midazolam
Sponsors: Mount Sinai School of Medicine; James Murrough
Recruiting - verified January 2012 - Conditions: Neuralgia; Postherpetic Neuralgia; Reflex Sympathetic Dystrophy
Interventions: Drug: Pennsaid topical 1.5% diclofenac; Drug: Placebo (2.3% DMSO solution)
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified March 2012 - Condition: Acute Respiratory Distress Syndrome
Interventions: Drug: Aspirin; Drug: Lactose powder
Sponsors: Mayo Clinic; Ognjen Gajic; Beth Israel Deaconess Medical Center; Montefiore Medical Center; Vanderbilt University
Not yet recruiting - verified January 2012 - Conditions: Acute Lymphoblastic Leukemia; Neuropathy; Neuropathic Pain
Interventions: Drug: gabapentin; Drug: placebo
Sponsors: St. Jude Children's Research Hospital; St. Jude Children's Research Hospital
Recruiting - verified January 2012 - Condition: Bipolar Disorder
Interventions: Drug: Ketamine hydrochloride injection; Drug: Flat tonic water (e.g., Canada Dry Tonic Water)
Sponsors: Juvenile Bipolar Research Foundation; Juvenile Bipolar Research Foundation
Not yet recruiting - verified April 2012 - Conditions: Chronic Low Back Pain; Degenerative Disc Disease; Depression; Anxiety
Interventions: Drug: Oxycodone; Drug: Morphine
Sponsors: Brigham and Women's Hospital; Brigham and Women's Hospital; Arthritis Foundation; National Institute on Drug Abuse (NIDA)
Recruiting - verified March 2012 - Condition: Psoriasis
Intervention:
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; Immunex Corporation
Recruiting - verified February 2012 - Condition: Acne Vulgaris
Interventions: Drug: Adapalene + benzoyl peroxide samples; Drug: Adapalene + benzoyl peroxide from standard tube
Sponsors: Wake Forest University; Wake Forest University; Galderma Laboratories, L.P.
Recruiting - verified January 2012 - Condition: Cocaine Dependence
Interventions: Drug: Ketamine; Drug: Lorazepam (control)
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2012 - Condition: Cleft Palate
Interventions: Drug: Oral acetaminophen; Drug: Ofirmev®; Drug: Opioid only
Sponsors: Loma Linda University; Loma Linda University
Recruiting - verified December 2011 - Condition: Chronic Pain
Intervention: Behavioral: Therapeutic Education System (TES) for chronic pain
Sponsors: National Development and Research Institutes, Inc.; National Development and Research Institutes, Inc.; National Institute on Drug Abuse (NIDA); Beth Israel Medical Center
Not yet recruiting - verified December 2011 - Condition: Alzheimer's Disease
Interventions: Drug: Resveratrol; Drug: Placebo
Sponsors: Alzheimer's Disease Cooperative Study (ADCS); Alzheimer's Disease Cooperative Study (ADCS); National Institute on Aging (NIA)
Recruiting - verified May 2012 - Condition: Acute Stroke
Intervention: Drug: Magnesium Sulfate
Sponsors: University of Southern California; University of Southern California; University of California, Los Angeles
Not yet recruiting - verified December 2011 - Conditions: Tethered Spinal Cord; Brain Tumor; Cranio Cervical Compression
Intervention: Other: Isoflurane, Propofol, Dexmedetomidine
Sponsors: Oregon Health and Science University; Oregon Health and Science University
Recruiting - verified January 2012 - Condition: Diabetic Peripheral Neuropathy
Interventions: Drug: DS-5565 tablet; Drug: pregabalin capsule; Drug: Placebo
Sponsors: Daiichi Sankyo Inc.; Daiichi Sankyo Inc.
Recruiting - verified March 2012 - Conditions: Migraine; Migraine Disorders; Headache
Interventions: Drug: Amitriptyline; Drug: Topiramate; Drug: Placebo
Sponsors: Children's Hospital Medical Center, Cincinnati; Children's Hospital Medical Center, Cincinnati; National Institute of Neurological Disorders and Stroke (NINDS)
Not yet recruiting - verified April 2012 - Conditions: Neonatal Neurobehavior; Breastfeeding Outcomes
Interventions: Drug: Bolus 10mL 0.25% bupivacaine/ep 1:600,000; infusion 10mL/hour 0.25% bupivacaine and epi 1:800,000; Drug: Bolus 10mL 0.25% bupivacaine/ epinephrine 1:600,000;infusion 10mL/hour 0.25% bupivacaine, 2 mcg/mL fentanyl, and epinephrine 1:800,000; Drug: Bolus 10mL 0.25% bupivacaine, 10mcg/mL fentanyl, and epi 1:600,000; infusion 10mL/hour 0.25% bupivacaine, 2.5 mcg/mL fentanyl, and epi 1:800,000; Drug: Bolus 10mL 0.25% bupivacaine, 5 mcg/mL fentanyl, and epi 1:600,000; infusion 10mL/hour 0.25% bupivacaine, 3.5 mcg/mL fentanyl, and epi 1:800,000; Drug: No epidural fentanyl or bupivacaine
Sponsors: University Hospital Case Medical Center; University Hospital Case Medical Center
Not yet recruiting - verified April 2012 - Condition: Postsurgical Dental Implant Surgery Pain
Intervention: Drug: Ketorolac Tromethamine Nasal Spray
Sponsors: Hersh, Elliot V., DMD, MS, PhD; Hersh, Elliot V., DMD, MS, PhD
Recruiting - verified December 2011 - Condition: Supraventricular Tachycardia
Interventions: Drug: Dexmedetomidine; Drug: Adenosine
Sponsors: University of Pittsburgh; University of Pittsburgh
Recruiting - verified February 2012 - Condition: Angiotensin-converting Enzyme (ACE) Inhibitor-associated Angioedema
Interventions: Drug: HOE-140; Other: Placebo
Sponsors: Vanderbilt University; Vanderbilt University; University of California, San Diego; Massachusetts General Hospital; University of California, Los Angeles
Recruiting - verified April 2012 - Conditions: Sciatica; Radiculopathy
Interventions: Procedure: epidural steroid injection; Procedure: Sham epidural steroid injection; Drug: Gabapentin; Drug: Placebo gabapentin
Sponsors: Johns Hopkins University; Johns Hopkins University; Walter Reed National Military Medical Center; Brooke Army Medical Center; Landstuhl Regional Medical Center; DC VA Hospital; San Diego Naval Hospital; Case Western Reserve University; Penn State-Hershey
Recruiting - verified March 2012 - Condition: Postoperative Dental Pain
Interventions: Drug: PF-05089771; Other: Placebo; Drug: PF-05089771; Other: Placebo; Drug: PF-05089771; Other: Placebo; Drug: Ibuprofen; Other: Placebo; Other: Placebo; Other: Placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified April 2012 - Condition: Polycystic Ovary Syndrome
Interventions: Drug: Salsalate; Drug: Salsalate
Sponsors: Indiana University; Indiana University
Recruiting - verified February 2012 - Conditions: Maternal Anaesthesia and Analgesia Affecting Fetus or Newborn; Breast Feeding; Fentanyl; Bupivacaine; Nalbuphine
Intervention:
Sponsors: University Hospital Case Medical Center; University Hospital Case Medical Center
Recruiting - verified February 2012 - Conditions: Acetaminophen Overdose; Pain
Intervention: Behavioral: Active Ingredient Icon
Sponsors: Northwestern University; Northwestern University; Emory University; McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.
Not yet recruiting - verified May 2012 - Conditions: Colon Cancer; Rectal Cancer; Colonic Diverticulosis
Interventions: Drug: Fentanyl; Drug: Propofol; Drug: Midazolam
Sponsors: Saint Joseph Mercy Health System; Saint Joseph Mercy Health System
Recruiting - verified December 2011 - Condition: Insomnia
Interventions: Drug: Dexmedetomidine; Drug: Zolpidem; Drug: Oral Placebo; Drug: Normal Saline placebo.
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; National Institutes of Health (NIH)
Recruiting - verified December 2011 - Condition: Dexmedetomidine Induced Sedation
Intervention: Drug: dexmedetomidine
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified April 2012 - Conditions: Pain, Postoperative; Bunion
Interventions: Drug: COV795; Drug: Placebo
Sponsors: Mallinckrodt; Mallinckrodt
Recruiting - verified April 2012 - Conditions: Acute Lymphoblastic Leukemia; Precursor B-Cell Lymphoblastic Leukemia; Precursor T-Cell Lymphoblastic Leukemia
Interventions: Drug: Decitabine; Drug: Vorinostat; Drug: Vincristine; Drug: Dexamethasone; Drug: Mitoxantrone; Drug: Pegaspargase; Drug: Methotrexate
Sponsors: Therapeutic Advances in Childhood Leukemia Consortium; Therapeutic Advances in Childhood Leukemia Consortium
Recruiting - verified March 2012 - Conditions: Peripheral Neuropathy; Type 1 Diabetes
Intervention: Drug: Salsalate
Sponsors: University of Michigan; University of Michigan
Recruiting - verified December 2011 - Conditions: Anemia, Sickle Cell; Pain
Interventions: Drug: Fentanyl Citrate; Drug: Normal Saline
Sponsors: Montefiore Medical Center; hnin khine
Recruiting - verified April 2012 - Condition: Allergic Conjunctivitis
Interventions: Drug: AL-4943A Ophthalmic Solution; Drug: AL-4943A Ophthalmic Solution Vehicle; Drug: Pataday
Sponsors: Alcon Research; Alcon Research
Recruiting - verified January 2012 - Condition: Osteoarthritis, Knee
Interventions: Device: Ivivi Torino II; Device: Ivivi Torino II
Sponsors: Amp Orthopedics, Inc.; Amp Orthopedics, Inc.
Recruiting - verified November 2011 - Conditions: Familial Adenomatous Polyposis; Attenuated Familial Adenomatous Polyposis
Interventions: Drug: Eflornithine plus Sulindac; Drug: Eflornithine and Placebo; Drug: Sulindac and Placebo
Sponsors: Cancer Prevention Pharmaceuticals, Inc.; Cancer Prevention Pharmaceuticals, Inc.
Not yet recruiting - verified March 2012 - Condition: Painful Osteoporotic Vertebral Compression Fractures (VCF)
Interventions: Device: Vertebral Augmentation (STABILIT); Other: Non-operative Management
Sponsors: DFINE Inc.; DFINE Inc.
Recruiting - verified February 2012 - Condition: Senile Purpura
Intervention: Drug: adapalene gel 0.3%
Sponsors: Multispecialty Aesthetic Clinical Research Organization; Multispecialty Aesthetic Clinical Research Organization; Galderma Laboratories, L.P.
Recruiting - verified April 2012 - Conditions: Adult Liposarcoma; Adult Synovial Sarcoma; Recurrent Adult Soft Tissue Sarcoma; Stage III Adult Soft Tissue Sarcoma; Stage IV Adult Soft Tissue Sarcoma
Interventions: Biological: recombinant interferon gamma; Biological: aldesleukin; Drug: cyclophosphamide; Other: laboratory biomarker analysis; Procedure: biopsy; Biological: NY-ESO-1-specific T lymphocytes
Sponsors: Fred Hutchinson Cancer Research Center; Fred Hutchinson Cancer Research Center; National Cancer Institute (NCI)
Recruiting - verified January 2012 - Condition: Diabetic Peripheral Neuropathy
Interventions: Drug: Pregabalin; Other: placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Condition: Coronary Artery Disease
Intervention: Drug: FFR Measurement with IV Adenoscan® then with Regadenoson
Sponsors: Ochsner Health System; Ochsner Health System; Astellas Pharma Global Development, Inc.
Recruiting - verified March 2012 - Condition: Craniotomy
Interventions: Drug: Acetaminophen; Other: No acetaminophen
Sponsors: Swedish Medical Center; Swedish Medical Center; Cadence Pharmaceuticals
Recruiting - verified May 2012 - Condition: Neuroendocrine Tumor
Intervention: Dietary Supplement: Resveratrol
Sponsors: University of Wisconsin, Madison; University of Wisconsin, Madison
Recruiting - verified February 2012 - Condition: Migraine
Interventions: Drug: Ketorolac; Drug: Placebo
Sponsors: Akron Children's Hospital; Akron Children's Hospital
Recruiting - verified February 2012 - Condition: Myopia
Intervention: Drug: Bromfenac
Sponsors: Virdi Eye Clinic; Virdi Eye Clinic
Recruiting - verified November 2011 - Condition: Postoperative Pain
Intervention: Drug: Morphine
Sponsors: Columbia University; Columbia University
Recruiting - verified February 2012 - Conditions: Acute Myelogenous Leukemia; Refractory Acute Myelogenous Leukemia
Interventions: Drug: Allopurinol; Drug: Fludarabine; Radiation: Total body irradiation; Drug: Cyclophosphamide; Drug: Levetiracetam; Drug: Busulfan; Biological: Umbilical Cord Blood Transplantation; Biological: Interleukin-2
Sponsors: Masonic Cancer Center, University of Minnesota; Masonic Cancer Center, University of Minnesota
Recruiting - verified November 2011 - Condition: Opioid Induced Constipation
Interventions: Drug: TD-1211; Drug: TD-1211; Drug: TD-1211; Drug: Placebo
Sponsors: Theravance; Theravance
Recruiting - verified November 2011 - Condition: Retraction of Colostomy
Interventions: Drug: IV morphine sulfate; Drug: SKY0402 (bupivacaine liposome injectable suspension)
Sponsors: Pacira Pharmaceuticals, Inc; Pacira Pharmaceuticals, Inc; Registrat-Mapi
Recruiting - verified February 2012 - Condition: Retraction of Colostomy
Interventions: Drug: Morphine Sulfate; Drug: bupivacaine liposome extended-release injectable suspension
Sponsors: Pacira Pharmaceuticals, Inc; Pacira Pharmaceuticals, Inc; Registrat-Mapi
Recruiting - verified February 2012 - Condition: Bowel Obstruction
Interventions: Drug: IV Morphine Sulfate; Drug: SKY0402 (bupivacaine liposome injectable suspension)
Sponsors: Pacira Pharmaceuticals, Inc; Pacira Pharmaceuticals, Inc; Registrat-Mapi
Recruiting - verified April 2012 - Condition: Bowel Obstruction
Interventions: Drug: IV Morphine Sulfate; Drug: SKY0402 (bupivacaine liposome extended-release injectable suspension)
Sponsors: Pacira Pharmaceuticals, Inc; Pacira Pharmaceuticals, Inc; Registrat-Mapi
Recruiting - verified January 2012 - Condition: Bowel Obstruction
Interventions: Drug: morphine sulfate; Drug: bupivacaine liposome extended-release injectable suspension
Sponsors: Pacira Pharmaceuticals, Inc; Pacira Pharmaceuticals, Inc; Registrat-Mapi
Recruiting - verified January 2012 - Condition: Bowel Obstruction
Interventions: Drug: IV morphine sulfate; Drug: SKY0402 (bupivacaine liposome extended-release injectable suspension)
Sponsors: Pacira Pharmaceuticals, Inc; Pacira Pharmaceuticals, Inc; Registrat-Mapi
Recruiting - verified January 2012 - Condition: Bowel Obstruction
Interventions: Drug: IV morphine sulfate; Drug: EXPAREL (bupivacaine liposome injectable suspension)
Sponsors: Pacira Pharmaceuticals, Inc; Pacira Pharmaceuticals, Inc; Registrat-Mapi
Recruiting - verified February 2012 - Condition: Bowel Obstruction
Interventions: Drug: Morphine Sulfate; Drug: bupivacaine liposome injectable suspension
Sponsors: Pacira Pharmaceuticals, Inc; Pacira Pharmaceuticals, Inc; Registrat-Mapi
Recruiting - verified April 2012 - Condition: BOWEL OBSTRUCTION
Interventions: Drug: Morphine Sulfate; Drug: bupivacaine liposome extended-release injectable suspension
Sponsors: Pacira Pharmaceuticals, Inc; Pacira Pharmaceuticals, Inc; Registrat-Mapi
Recruiting - verified April 2012 - Condition: Bowel Obstruction
Interventions: Drug: IV morphine sulfate; Drug: SKY0402 (bupivacaine liposome injectable suspension)
Sponsors: Pacira Pharmaceuticals, Inc; Pacira Pharmaceuticals, Inc; Registrat-Mapi
Recruiting - verified January 2012 - Conditions: Osteoarthritis; Rheumatoid Arthritis; Ankylosing Spondylitis; Other Arthritic Conditions (e.g., Psoriatic Arthritis)
Intervention: Behavioral: painACTION: Arthritis
Sponsors: Inflexxion, Inc.; Inflexxion, Inc.
Recruiting - verified October 2011 - Condition: Morbid Obesity
Interventions: Drug: IV acetaminophen; Drug: IV normal saline
Sponsors: McLaren Regional Medical Center; McLaren Regional Medical Center; Cadence Pharmaceuticals
Recruiting - verified October 2011 - Condition: Painful Diabetic Peripheral Neuropathy
Interventions: Drug: pregabalin; Drug: placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Conditions: Epilepsy, Partial Seizures; Epilepsy, Primary Generalized Tonic-Clonic Seizures
Intervention: Drug: Pregabalin
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Conditions: Uterine Fibroids; Uterine Artery Embolization
Interventions: Drug: pregabalin/celecoxib; Drug: pregabalin/placebo; Drug: celecoxib/placebo; Drug: Placebo group
Sponsors: Northwestern University; Northwestern University
Recruiting - verified March 2012 - Condition: Hereditary Angioedema
Intervention: Drug: Icatibant
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; Shire Human Genetic Therapies, Inc.
Recruiting - verified April 2012 - Condition: Graft Versus Host Disease
Interventions: Drug: Cyclophospahmide and Sirolimus; Drug: Low dose IL-2, Cyclophosphamide and Sirolimus; Drug: Low dose IL-2, low dose Vidaza, cyclophosphamide & Sirolimus
Sponsors: Hackensack University Medical Center; Hackensack University Medical Center
Recruiting - verified October 2011 - Condition: Chronic Low Back Pain
Interventions: Drug: Hydrocodone bitartrate q24h film-coated tablets; Drug: Placebo to match hydrocodone bitartrate q24h tablets
Sponsors: Purdue Pharma LP; Purdue Pharma LP
Recruiting - verified May 2012 - Condition: Pelvis Pain Chronic
Intervention: Drug: Duloxetine
Sponsors: University of Maryland; University of Maryland; Eli Lilly and Company
Recruiting - verified October 2011 - Condition: Low Back Pain
Intervention: Drug: Hydromorphone ER
Sponsors: Rehabilitation Institute of Chicago; Rehabilitation Institute of Chicago; Mallinckrodt
Recruiting - verified February 2012 - Condition: Interscalene Blockade in Elective Arthroscopic Rotator Cuff Repair
Interventions: Drug: Ropivacaine; Drug: Dexamethasone; Drug: Dexamethasone; Drug: Normal saline; Drug: Normal saline
Sponsors: Mayo Clinic; Mayo Clinic
Recruiting - verified May 2012 - Conditions: Lung Cancer; Head and Neck Cancer; Hearing Loss; Ototoxicity; Tinnitus; Neuropathy
Interventions: Drug: SPI-1005 Low Dose; Drug: SPI-1005 Middle dose; Drug: SPI-1005 High Dose; Drug: Placebo
Sponsors: Sound Pharmaceuticals, Incorporated; Sound Pharmaceuticals, Incorporated; VA Puget Sound Health Care System
Not yet recruiting - verified October 2011 - Condition: Eye Allergies
Interventions: Drug: Olopatadine hydrochloride 0.2%; Drug: Bepotastine besilate ophthalmic solution 1.5%
Sponsors: McCabe Vision Center; McCabe Vision Center
Recruiting - verified October 2011 - Condition: Neonatal Abstinence Syndrome
Interventions: Drug: sublingual buprenorphine; Drug: oral morphine
Sponsors: Thomas Jefferson University; Thomas Jefferson University; National Institute on Drug Abuse (NIDA)
Recruiting - verified November 2011 - Condition: Pain
Interventions: Other: Ear Acupuncture; Drug: Standard Treatment
Sponsors: Mike O'Callaghan Federal Hospital; Mike O'Callaghan Federal Hospital
Recruiting - verified April 2012 - Condition: Hematologic Diseases
Interventions: Drug: Interleukin-2 (100,000 international units); Drug: Interleukin-2 (200,000 international units)
Sponsors: National Institutes of Health Clinical Center (CC); National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified September 2011 - Condition: Temporary Auditory Threshold Shift
Interventions: Drug: SPI-1005 Low dose; Drug: SPI-1005 Middle dose; Drug: SPI-1005 High dose; Drug: Placebo
Sponsors: Sound Pharmaceuticals, Incorporated; Sound Pharmaceuticals, Incorporated; University of Florida
Recruiting - verified October 2011 - Conditions: Breast Neoplasms; Breast Cancer
Interventions: Drug: Taxane; Drug: Taxotere; Drug: Abraxane; Drug: Ixabepilone
Sponsors: The Methodist Hospital System; The Methodist Hospital System
Recruiting - verified September 2011 - Conditions: Hepatitis C; Medication Adherence
Interventions: Other: enhanced DOT (both pegylated interferon alfa-2a and ribavirin); Other: standard DOT (PEG-DOT control arm)
Sponsors: Albert Einstein College of Medicine of Yeshiva University; Albert Einstein College of Medicine of Yeshiva University; National Institute on Drug Abuse (NIDA)
Recruiting - verified September 2011 - Condition: Pain
Interventions: Drug: 150% Oral Morphine Equivalent (OME); Other: Clinical Judgment
Sponsors: Abbott Northwestern Hospital; Abbott Northwestern Hospital; Allina Hospitals and Clinics
Recruiting - verified October 2011 - Condition: Opioid Induced Constipation
Interventions: Drug: Placebo once daily; Drug: 0.1 mg of S-297995 once daily; Drug: 0.2 mg of S-297995 once daily; Drug: 0.4 mg of S-297995 once daily
Sponsors: Shionogi Inc.; Shionogi
Recruiting - verified October 2011 - Conditions: Anesthesia; Neuromuscular Blockade
Interventions: Drug: Remifentanil infusion; Drug: Rocuronium dose + Remifentanil infusion; Drug: Rocuronium dose + Remifentanil infusion; Drug: Rocuronium dose + Remifentanil infusion; Drug: Remifentanil infusion; Drug: Rocuronium dose + Remifentanil infusion; Drug: Rocuronium dose + Remifentanil infusion; Drug: Rocuronium dose + Remifentanil infusion
Sponsors: Covidien; Covidien
Recruiting - verified May 2012 - Condition: Bipolar Depression
Interventions: Drug: ESC + CBX; Drug: ESC + PBO.; Drug: ESC+CBX
Sponsors: Loyola University; Loyola University; Stanley Medical Research Institute
Recruiting - verified December 2011 - Conditions: Tourniquet-induced Pain; Tourniquet-induced Hypertension
Interventions: Drug: gabapentin 600 mg po; Drug: Placebo pill given one hour before surgery
Sponsors: Baylor College of Medicine; Baylor College of Medicine
Not yet recruiting - verified September 2011 - Condition: Neoplasms
Interventions: Drug: Gemcitabine; Drug: BAY80-6946; Drug: Cisplatin; Drug: NaCl; Drug: BAY80-6964 fixed dose
Sponsors: Bayer; Bayer
Recruiting - verified May 2012 - Condition: Multiple Myeloma
Interventions: Drug: Cyclophosphamide; Drug: Velcade; Drug: Chloroquine
Sponsors: New York University School of Medicine; New York University School of Medicine; Millennium Pharmaceuticals, Inc.
Recruiting - verified April 2012 - Condition: Hypoventilation
Interventions: Drug: Placebo; Drug: Ketamine infusion
Sponsors: Northwestern University; Northwestern University
Recruiting - verified May 2012 - Conditions: Pain; Opioid Use, Unspecified, Uncomplicated
Interventions: Drug: Placebo infusion of .9 normal saline; Drug: administration of magnesium sulfate
Sponsors: Northwestern University; Northwestern University
Recruiting - verified February 2012 - Condition: Opiate Dependence
Interventions: Other: Patient-Centered Methadone Treatment; Other: Methadone Treatment as usual
Sponsors: Friends Research Institute, Inc.; Friends Research Institute, Inc.
Recruiting - verified September 2011 - Condition: Low Back Pain
Interventions: Drug: Oxycodone/Naloxone controlled-release; Drug: Oxycodone HCl controlled-release; Drug: Placebo
Sponsors: Purdue Pharma LP; Purdue Pharma LP
Recruiting - verified May 2012 - Condition: Low Back Pain
Interventions: Drug: Oxycodone/Naloxone controlled-release; Drug: Oxycodone HCl controlled-release; Drug: Placebo
Sponsors: Purdue Pharma LP; Purdue Pharma LP
Recruiting - verified May 2012 - Condition: Fibromyalgia
Interventions: Drug: Pregabalin; Drug: placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Condition: Bipolar Disorder Depression
Interventions: Drug: Minocycline; Drug: Aspirin; Drug: placebo
Sponsors: Laureate Institute for Brain Research, Inc.; Laureate Institute for Brain Research, Inc.; Stanley Medical Research Institute; University of Oklahoma
Recruiting - verified March 2012 - Condition: Pain
Interventions: Drug: Hydromorphone; Drug: Usual care
Sponsors: Montefiore Medical Center; Montefiore Medical Center
Recruiting - verified September 2011 - Condition: Post-surgical Dental Pain
Interventions: Drug: PF-04531083; Other: Placebo; Drug: PF-04531083; Other: Placebo; Drug: Ibuprofen; Other: Placebo; Other: Placebo; Other: Placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified April 2012 - Conditions: Contraceptive Usage; Opioid Dependence
Interventions: Behavioral: Contraceptive management program; Other: Usual care
Sponsors: University of Vermont; University of Vermont
Recruiting - verified December 2011 - Condition: Acne Vulgaris
Interventions: Drug: Fixed Combination dapsone/adapalene Formulation A Gel; Drug: Fixed Combination dapsone/adapalene Formulation B Gel; Drug: dapsone 5% gel; Drug: adapalene 0.3% gel
Sponsors: Allergan; Allergan
Not yet recruiting - verified May 2012 - Condition: Pain
Intervention: Other: Drug Dose
Sponsors: Stanford University; Stanford University
Recruiting - verified August 2011 - Condition: Primary Hypomagnesemia (Disorder)
Intervention: Drug: Magnesium Sulfate
Sponsors: CAMC Health System; CAMC Health System; Sara and Pauline Maier Foundation, Inc.
Recruiting - verified December 2011 - Condition: Constipation
Interventions: Other: Opioid Dose Intervention; Other: Opioid Assessment Intervention; Other: Vinca Alkaloid Assessment Intervention
Sponsors: H. Lee Moffitt Cancer Center and Research Institute; H. Lee Moffitt Cancer Center and Research Institute; National Institutes of Health (NIH); University of South Florida
Recruiting - verified January 2012 - Condition: Neuroblastoma
Intervention: Biological: Humanized 3F8 Monoclonal Antibody (Hu3F8)
Sponsors: Memorial Sloan-Kettering Cancer Center; Memorial Sloan-Kettering Cancer Center
Recruiting - verified March 2012 - Condition: Insomnia
Intervention: Drug: Gabapentin
Sponsors: University at Buffalo; University at Buffalo
Recruiting - verified August 2011 - Condition: Opiate Dependence
Intervention: Behavioral: employment based reinforcement
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2010 - Condition: Metastatic Melanoma
Interventions: Other: Radiation therapy and high-dose IL-2; Drug: High-dose IL-2
Sponsors: Providence Health & Services; Providence Health & Services; Prometheus Laboratories
Recruiting - verified August 2011 - Condition: Multiple Sclerosis
Interventions: Drug: diclofenac sodium topical gel; Other: Placebo
Sponsors: Brown, Theodore R., M.D., MPH; Brown, Theodore R., M.D., MPH; Teva Neuroscience, Inc.
Recruiting - verified October 2011 - Condition: Postop Adult ICU Patients
Intervention: Procedure: Provide Music to Adult Postop Patients in the ICU.
Sponsors: National Institutes of Health Clinical Center (CC); National Institutes of Health Clinical Center (CC)
Recruiting - verified March 2012 - Condition: Melanoma
Interventions: Drug: Ipilimumab; Drug: Temozolomide; Drug: Cisplatin; Drug: Interferon Alfa-2b; Drug: Interleukin-2
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center
Not yet recruiting - verified February 2012 - Condition: Cocaine Dependence
Interventions: Drug: Buprenorphine + Naltrexone; Drug: Placebo + Naltrexone
Sponsors: University of California, Los Angeles; Walter Ling; National Institute on Drug Abuse (NIDA); The EMMES Corporation
Recruiting - verified February 2012 - Conditions: Depression; Depressive Disorder; Depressive Disorder, Major
Interventions: Drug: Buprenorphine; Drug: Placebo
Sponsors: University of Pittsburgh; University of Pittsburgh; National Alliance for Research on Schizophrenia and Depression
Recruiting - verified January 2012 - Condition: Analgesia After ED Discharge for Extremity Injuries
Intervention: Drug: Oral Opioid Pain Medicine
Sponsors: Montefiore Medical Center; Montefiore Medical Center
Recruiting - verified December 2011 - Condition: Opioid Induced Constipation
Intervention: Drug: TD-1211
Sponsors: Theravance; Theravance
Recruiting - verified October 2011 - Condition: Cocaine Abuse
Intervention: Behavioral: prize contingency management
Sponsors: University of Connecticut Health Center; University of Connecticut Health Center; National Institute on Drug Abuse (NIDA)
Recruiting - verified November 2011 - Condition: Pain, Postoperative
Intervention: Drug: Intravenous Acetaminophen
Sponsors: Children's Hospital of Philadelphia; Children's Hospital of Philadelphia
Recruiting - verified October 2011 - Condition: Chronic Nonmalignant and Nonneuropathic Pain
Intervention: Drug: Hydrocodone bitartrate q24h film-coated tablets
Sponsors: Purdue Pharma LP; Purdue Pharma LP
Recruiting - verified April 2012 - Conditions: Leukemia; Lymphoma
Interventions: Drug: dexamethasone; Drug: methotrexate; Drug: mitoxantrone hydrochloride; Drug: pegaspargase; Drug: temsirolimus; Drug: vincristine sulfate; Other: laboratory biomarker analysis; Other: pharmacological study
Sponsors: National Cancer Institute (NCI); Children's Oncology Group; National Cancer Institute (NCI)
Recruiting - verified May 2012 - Condition: Pulmonary Disease, Chronic Obstructive
Interventions: Drug: Tetrahydrobiopterin (BH4); Drug: non-acetylated salicylate; Dietary Supplement: High Fat Meal; Drug: L-NMMA; Dietary Supplement: Antioxidant Cocktail
Sponsors: Georgia Health Sciences University; Georgia Health Sciences University; American Heart Association
Recruiting - verified July 2011 - Conditions: Dyskinesia; Levodopa Induced Dyskinesia; Parkinson's Disease
Intervention: Drug: ADS-5102 (extended release amantadine HCl)
Sponsors: Adamas Pharmaceuticals, Inc.; Adamas Pharmaceuticals, Inc.
Recruiting - verified May 2012 - Condition: Fibromyalgia
Intervention: Drug: Pregabalin
Sponsors: Newton-Wellesley Hospital; Newton-Wellesley Hospital; Pfizer
Not yet recruiting - verified July 2011 - Condition: Opioid Abuse
Intervention: Drug: pioglitazone
Sponsors: Columbia University; Columbia University; Omeros Corporation
Recruiting - verified July 2011 - Conditions: Heroin Dependence; Nicotine Dependence
Interventions: Drug: Pioglitazone; Drug: Placebo
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute on Drug Abuse (NIDA); Omeros Corporation
Recruiting - verified July 2011 - Condition: CAD
Intervention:
Sponsors: Creighton University; Creighton University
Recruiting - verified January 2012 - Condition: Neuroblastoma
Interventions: Drug: Zoledronic Acid; Biological: Aldesleukin
Sponsors: University of Alabama at Birmingham; Joseph Pressey, MD
Recruiting - verified December 2011 - Condition: Marijuana Smoking
Interventions: Drug: Dronabinol; Drug: Placebo
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute on Drug Abuse (NIDA)
Recruiting - verified November 2010 - Condition: Airway Remodeling
Interventions: Drug: Dexmedetomidine; Drug: propofol
Sponsors: Milton S. Hershey Medical Center; Milton S. Hershey Medical Center
Not yet recruiting - verified January 2012 - Conditions: Leukemia; Chronic Myelogenous Leukemia
Interventions: Drug: Fludarabine; Drug: Busulfan; Procedure: NK cell infusion:; Drug: Interleukin-2; Drug: Anti-Thymocyte Globulin; Procedure: Allogeneic related Stem Cell Transplant; Drug: Tacrolimus; Drug: Methotrexate
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center; National Cancer Institute (NCI)
Recruiting - verified April 2012 - Condition: Epilepsy, Partial Seizures
Interventions: Drug: Pregabalin add-on therapy; Drug: Pregabalin add-on therapy; Drug: Pregabalin add-on therapy
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Condition: Opioid-Induced Constipation (OIC)
Interventions: Drug: NKTR-118; Drug: NKTR-118; Drug: Placebo
Sponsors: AstraZeneca; AstraZeneca
Recruiting - verified January 2012 - Condition: Hereditary Angioedema
Intervention: Drug: icatibant
Sponsors: Shire Human Genetic Therapies, Inc.; Shire Human Genetic Therapies, Inc.
Recruiting - verified May 2012 - Conditions: Nicotine Dependence; Opiate Dependence
Interventions: Behavioral: Intensive, tailored intervention; Behavioral: NJ Quitline Referral
Sponsors: University of Medicine and Dentistry New Jersey; University of Medicine and Dentistry New Jersey; National Institute on Drug Abuse (NIDA)
Recruiting - verified January 2012 - Conditions: Pain; Sickle Cell Disease
Interventions: Drug: Morphine; Drug: Nubain
Sponsors: Children's Healthcare of Atlanta; Children's Healthcare of Atlanta; Atlanta Clinical and Translational Science Institute
Recruiting - verified September 2009 - Condition: Opioid Dependence
Interventions: Drug: Opioid detoxification using buprenorphine vs. oral naltrexone; Drug: Buprenorphine
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute
Recruiting - verified June 2011 - Conditions: Post Infective IBS-D; Irritable Bowel Syndrome With Diarrhea
Intervention: Drug: Mesalamine
Sponsors: University of Utah; University of Utah; Shire Human Genetic Therapies, Inc.
Recruiting - verified August 2011 - Condition: Breast Cancer
Intervention: Other: Diclofenac epolamine patch
Sponsors: Northwestern University; Northwestern University
Recruiting - verified May 2012 - Condition: Knee Osteoarthritis
Intervention: Drug: Voltaren
Sponsors: Brigham and Women's Hospital; Brigham and Women's Hospital; Endo Pharmaceuticals
Recruiting - verified June 2011 - Conditions: Age-associated Cognitive Impairment; Mild Cognitive Impairment (MCI)
Interventions: Dietary Supplement: Curcumin; Dietary Supplement: Sugar pill
Sponsors: University of California, Los Angeles; University of California, Los Angeles
Recruiting - verified April 2012 - Conditions: Tobacco Use Disorder; Medication Adherence
Intervention: Behavioral: Varenicline treatment as usual or directly observed therapy
Sponsors: Albert Einstein College of Medicine of Yeshiva University; Albert Einstein College of Medicine of Yeshiva University; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Conditions: Human Immunodeficiency Virus; Acquired Immunodeficiency Syndrome; Opiate Addiction; Drug Dependence
Intervention: Drug: Buprenorphine/naloxone
Sponsors: Yale University; Yale University; George Mason University; Howard University
Recruiting - verified April 2012 - Condition: Inflammatory Response
Interventions: Drug: Ibuprofen; Drug: Placebo/Saline solution
Sponsors: New York University School of Medicine; New York University School of Medicine
Recruiting - verified June 2011 - Conditions: Osteoarthritis; Chronic Pain
Intervention: Drug: duloxetine, diclofenac
Sponsors: University of Michigan; University of Michigan; National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS); National Center for Research Resources (NCRR); Merck; Nuvo Research Inc.
Recruiting - verified March 2012 - Conditions: Alpha-1-antitrypsin Deficiency; Liver Cirrhosis
Interventions: Drug: Drug-Carbamazepine (Tegretol XR); Drug: Carbamazepine (Tegretol XR) Placebo
Sponsors: University of Pittsburgh; University of Pittsburgh; Novartis; National Institutes of Health (NIH); National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Not yet recruiting - verified January 2012 - Condition: Pain, Postoperative
Intervention: Drug: Ketolorac
Sponsors: The Cleveland Clinic; The Cleveland Clinic
Not yet recruiting - verified February 2012 - Condition: Opioid Use During Medical Care
Intervention:
Sponsors: Albany Medical College; Albany Medical College
Recruiting - verified June 2011 - Condition: Leukemia
Interventions: Drug: asparaginase; Drug: bortezomib; Drug: cytarabine; Drug: daunorubicin hydrochloride; Drug: etoposide; Drug: mitoxantrone hydrochloride; Drug: sorafenib tosylate
Sponsors: National Cancer Institute (NCI); Children's Oncology Group; National Cancer Institute (NCI)
Recruiting - verified May 2012 - Conditions: Acute Myeloid Leukemia; Myelodysplastic Syndrome
Interventions: Drug: Preparative Regimen; Biological: NK Cell Product; Drug: Interleukin-2; Biological: Donor CD34+ Cells; Biological: Anti-thymocyte globulin
Sponsors: Masonic Cancer Center, University of Minnesota; Masonic Cancer Center, University of Minnesota
Recruiting - verified April 2012 - Conditions: Chronic Pain; Opioid Dependence
Interventions: Drug: Varenicline; Drug: Placebo
Sponsors: Mayo Clinic; Mayo Clinic
Recruiting - verified May 2012 - Condition: Pain
Intervention: Drug: Oxycodone hydrochloride controlled-release tablets
Sponsors: Purdue Pharma LP; Purdue Pharma LP
Recruiting - verified May 2012 - Condition: Osteoarthritis of the Knee
Interventions: Drug: ARRY-371797, p38 inhibitor; oral; Drug: Oxycodone hydrochloride (HCl) extended release (ER), opioid agonist; oral; Drug: Placebo; oral
Sponsors: Array BioPharma; Array BioPharma
Recruiting - verified March 2012 - Condition: Lumbar Spinal Fusions
Interventions: Drug: Pregabalin 150 mg; Drug: Placebo
Sponsors: Hospital for Special Surgery, New York; Hospital for Special Surgery, New York; Pfizer
Recruiting - verified June 2011 - Condition: Sialorrhoea
Interventions: Drug: OC oral solution treatment A; Drug: OC oral solution treatment B; Drug: OC oral solution treatment C; Drug: OC oral solution treatment D
Sponsors: Orient Pharma Co., Ltd.; Orient Pharma Co., Ltd.
Recruiting - verified May 2012 - Condition: Obsessive Compulsive Disorder
Interventions: Drug: Ketamine; Drug: Midazolam
Sponsors: Goodman, Wayne, M.D.; Goodman, Wayne, M.D.
Not yet recruiting - verified June 2011 - Condition: Chronic Graft-versus-host Disease
Intervention: Drug: Interleukin-2
Sponsors: Dana-Farber Cancer Institute; Dana-Farber Cancer Institute; National Cancer Institute (NCI); Prometheus Laboratories
Recruiting - verified July 2011 - Condition: Idiopathic Pulmonary Fibrosis
Interventions: Drug: Pirfenidone; Drug: Placebo
Sponsors: InterMune; InterMune
Recruiting - verified June 2011 - Condition: Cardiopulmonary Bypass Induced Lipid Peroxidation
Intervention: Drug: Acetaminophen
Sponsors: Vanderbilt University; Vanderbilt University
Not yet recruiting - verified June 2011 - Condition: Depression
Interventions: Drug: Ketamine; Drug: methohexital
Sponsors: Mayo Clinic; Mayo Clinic
Recruiting - verified March 2012 - Conditions: Pain; Advanced Cancer
Interventions: Drug: Sativex®; Drug: Placebo (GA-0034)
Sponsors: GW Pharmaceuticals Ltd.; GW Pharmaceuticals Ltd.; Otsuka Pharmaceutical Development & Commercialization, Inc.
Recruiting - verified August 2011 - Condition: Pain
Interventions: Drug: Preservative free morphine; Drug: Fentanyl
Sponsors: Goodman, Evan, M.D.; Goodman, Evan, M.D.
Recruiting - verified May 2011 - Condition: Chronic Kidney Disease
Intervention:
Sponsors: North Shore Long Island Jewish Health System; Staten Island University Hospital
Recruiting - verified April 2011 - Condition: Chronic Pain
Intervention: Drug: Ketamine
Sponsors: University of Rochester; University of Rochester
Recruiting - verified May 2011 - Condition: Low Back Pain
Interventions: Drug: Oxycodone/Naloxone Controlled-release; Drug: Placebo
Sponsors: Purdue Pharma LP; Purdue Pharma LP
Recruiting - verified February 2012 - Condition: Pain
Interventions: Drug: Ketorolac; Drug: Ibuprofen
Sponsors: Planned Parenthood League of Massachusetts; Planned Parenthood League of Massachusetts; Society of Family Planning
Recruiting - verified May 2012 - Condition: Conscious Sedation
Interventions: Drug: Ketamine; Drug: Ketamine Co-administered with Propofol
Sponsors: Children's Hospital Colorad; Children's Hospital Colorad; Colorado Clinical & Translational Sciences Institute
Recruiting - verified December 2011 - Condition: Multiple Myeloma
Interventions: Drug: Amrubicin; Drug: Lenalidomide; Drug: Dexamethasone; Drug: Aspirin
Sponsors: Stanford University; Stanford University; Celgene Corporation
Recruiting - verified October 2011 - Condition: Juvenile Idiopathic Arthritis
Interventions: Drug: naproxen; Drug: esomeprazole
Sponsors: AstraZeneca; AstraZeneca
Recruiting - verified June 2011 - Condition: Impaired Glucose Tolerance
Interventions: Dietary Supplement: resveratrol; Drug: Placebo
Sponsors: Albert Einstein College of Medicine of Yeshiva University; Albert Einstein College of Medicine of Yeshiva University; American Diabetes Association
Recruiting - verified June 2011 - Condition: Leukemia
Interventions: Drug: alvocidib; Drug: cytarabine; Drug: daunorubicin hydrochloride; Drug: idarubicin; Drug: mitoxantrone hydrochloride
Sponsors: National Cancer Institute (NCI); Sidney Kimmel Comprehensive Cancer Center; National Cancer Institute (NCI)
Recruiting - verified May 2012 - Condition: Acute Myelogenous Leukemia
Interventions: Drug: FLAM; Drug: 7&3
Sponsors: Sidney Kimmel Comprehensive Cancer Center; Sidney Kimmel Comprehensive Cancer Center
Recruiting - verified January 2012 - Conditions: Melanoma; Metastatic Kidney Cancer
Intervention: Drug: Interleukin-2 (IL-2)
Sponsors: Loma Linda University; Loma Linda University
Recruiting - verified October 2011 - Condition: Breast Cancer
Interventions: Drug: Celecoxib; Drug: Placebo; Drug: Cholecalciferol
Sponsors: University of North Dakota; University of North Dakota; Department of Defense
Recruiting - verified August 2011 - Conditions: Sarcoma; Melanoma; Epithelial Malignancies; Pleural Malignancy
Interventions: Biological: Epigenetically Modified Autologous Tumor; Drug: Cyclophosphamide; Drug: Celecoxib
Sponsors: National Institutes of Health Clinical Center (CC); National Cancer Institute (NCI)
Recruiting - verified December 2011 - Conditions: Adult Acute Megakaryoblastic Leukemia (M7); Adult Acute Minimally Differentiated Myeloid Leukemia (M0); Adult Acute Monoblastic Leukemia (M5a); Adult Acute Monocytic Leukemia (M5b); Adult Acute Myeloblastic Leukemia With Maturation (M2); Adult Acute Myeloblastic Leukemia Without Maturation (M1); Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Adult Acute Myelomonocytic Leukemia (M4); Adult Erythroleukemia (M6a); Adult Pure Erythroid Leukemia (M6b); Recurrent Adult Acute Myeloid Leukemia
Interventions: Drug: cyclosporine; Drug: pravastatin sodium; Drug: mitoxantrone hydrochloride; Drug: etoposide; Procedure: bone marrow aspiration
Sponsors: Fred Hutchinson Cancer Research Center; Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium; National Cancer Institute (NCI)
Recruiting - verified April 2012 - Conditions: Recurrent Melanoma; Stage IV Melanoma
Interventions: Drug: cyclophosphamide; Biological: aldesleukin; Biological: autologous tumor cell vaccine; Other: laboratory biomarker analysis; Other: immunologic technique; Other: immunohistochemistry staining method; Genetic: polymerase chain reaction; Biological: therapeutic autologous lymphocytes
Sponsors: Fred Hutchinson Cancer Research Center; Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium; National Cancer Institute (NCI)
Recruiting - verified March 2012 - Conditions: Chronic Pain; Opiate Dependence
Interventions: Behavioral: Cognitive-Behavioral Therapy for Pain and Opioid Dependence; Behavioral: Methadone Drug Counseling
Sponsors: Yale University; Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified May 2012 - Condition: Neuroblastoma
Interventions: Biological: hu14.18-IL2 fusion protein; Biological: sargramostim; Drug: isotretinoin; Other: laboratory biomarker analysis
Sponsors: National Cancer Institute (NCI); Children's Oncology Group; National Cancer Institute (NCI)
Recruiting - verified May 2012 - Condition: Pain
Intervention: Drug: Intravenous ibuprofen
Sponsors: Cumberland Pharmaceuticals; Cumberland Pharmaceuticals
Recruiting - verified April 2012 - Conditions: Pain; Fever
Intervention: Drug: Intravenous ibuprofen
Sponsors: Cumberland Pharmaceuticals; Cumberland Pharmaceuticals
Recruiting - verified May 2012 - Condition: Cardiovascular Disease, Rheumatoid Arthritis
Interventions: Drug: tocilizumab [RoActemra/Actemra]; Drug: etanercept
Sponsors: Hoffmann-La Roche; Hoffmann-La Roche
Recruiting - verified March 2012 - Condition: Tonsillectomy
Interventions: Drug: Intravenous ibuprofen; Other: Normal Saline
Sponsors: Cumberland Pharmaceuticals; Cumberland Pharmaceuticals
Recruiting - verified January 2012 - Condition: Primary Total Knee Arthroplasty
Interventions: Drug: Pregabalin 50mg; Drug: Pregabalin 100mg; Drug: Pregabalin 150mg; Drug: Placebo
Sponsors: Hospital for Special Surgery, New York; Hospital for Special Surgery, New York
Recruiting - verified December 2011 - Condition: Traumatic Brain Injury
Interventions: Device: Arctic Sun; Drug: Magnesium Sulfate
Sponsors: Department of Defense; Department of Defense
Recruiting - verified December 2011 - Condition: Opioid-induced Constipation (OIC)
Interventions: Drug: TD-1211; Drug: Placebo
Sponsors: Theravance; Theravance
Recruiting - verified February 2012 - Conditions: Premature Birth of Newborn; Critically Ill
Interventions: Drug: Methadone; Drug: Methadone
Sponsors: Children's Research Institute; Children's Research Institute
Recruiting - verified April 2012 - Condition: Pain
Intervention: Drug: Acetaminophen
Sponsors: Children's Research Institute; Children's Research Institute
Recruiting - verified April 2012 - Condition: Pain
Interventions: Drug: Fentanyl; Drug: Fentanyl
Sponsors: Johns Hopkins University; Johns Hopkins University
Recruiting - verified April 2012 - Condition: Opioid-Induced Constipation (OIC)
Interventions: Drug: NKTR-118; Drug: NKTR-118; Drug: Placebo
Sponsors: AstraZeneca; AstraZeneca
Recruiting - verified January 2012 - Conditions: Temporomandibular Disorder; Facial Pain
Interventions: Drug: Naltrexone; Drug: Placebo
Sponsors: University of Florida; University of Florida; American Pain Society
Recruiting - verified March 2011 - Condition: Pain
Intervention: Drug: Buprenorphine transdermal system
Sponsors: Purdue Pharma LP; Purdue Pharma LP
Recruiting - verified December 2011 - Conditions: Mechanically Ventilated Neonates,; Painful Procedures in Newborns
Intervention: Drug: Codeine
Sponsors: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - verified February 2012 - Condition: Menstrual Migraine
Interventions: Drug: sumatriptan/naproxen sodium; Drug: placebo
Sponsors: Cady, Roger, M.D.; Cady, Roger, M.D.; GlaxoSmithKline
Recruiting - verified February 2012 - Condition: Acute Kidney Injury
Interventions: Drug: ATG; Drug: Rituximab; Drug: Methylprednisolone; Drug: Diphenhydramine; Drug: Acetaminophen; Drug: Tacrolimus; Drug: Sirolimus; Drug: Hydrocortisone; Drug: Prednisone
Sponsors: National Institute of Allergy and Infectious Diseases (NIAID); National Institute of Allergy and Infectious Diseases (NIAID); Immune Tolerance Network (ITN)
Recruiting - verified August 2011 - Condition: Rheumatoid Arthritis
Intervention: Drug: etanercept
Sponsors: Amgen; Amgen
Recruiting - verified March 2012 - Condition: Acute Pain
Interventions: Drug: H2O; Drug: 1+1
Sponsors: Montefiore Medical Center; Montefiore Medical Center
Recruiting - verified March 2011 - Conditions: Idiopathic Scoliosis; Spondylolisthesis
Interventions: Drug: Ketamine; Drug: Normal Saline
Sponsors: Children's Research Institute; Children's Research Institute
Recruiting - verified March 2012 - Condition: Low Back Pain
Interventions: Other: Medical Care; Other: Dual Care; Other: Shared Care
Sponsors: Palmer College of Chiropractic; Palmer College of Chiropractic; Health Resources and Services Administration (HRSA); Genesis Family Medical Center; University of Iowa; Thomas Jefferson University
Recruiting - verified January 2012 - Conditions: Brain Injuries; Craniocerebral Trauma; Trauma, Nervous System; Traumatic Brain Injury
Interventions: Drug: IV Propranolol and Per Tube Clonidine; Drug: Placebo
Sponsors: Vanderbilt University; Vanderbilt University
Recruiting - verified March 2012 - Conditions: Epilepsy; Anxiety
Interventions: Drug: Pregabalin-Lyrica; Drug: Sertraline
Sponsors: Rush University Medical Center; Rush University Medical Center
Recruiting - verified September 2011 - Condition: Major Depressive Disorder
Interventions: Drug: Ketamine; Drug: placebo
Sponsors: Mount Sinai School of Medicine; James Murrough
Recruiting - verified December 2011 - Condition: Acute Sore Throat
Intervention: Device: Ear Acupuncture
Sponsors: Mike O'Callaghan Federal Hospital; Mike O'Callaghan Federal Hospital
Recruiting - verified April 2012 - Condition: Diabetic Peripheral Neuropathic Pain
Interventions: Drug: BMS-954561; Drug: Pregabalin; Drug: BMS-954561; Drug: Placebo matching BMS-954561; Drug: Placebo matching Pregabalin
Sponsors: Bristol-Myers Squibb; Bristol-Myers Squibb
Recruiting - verified March 2011 - Condition: Colon Cancer
Interventions: Dietary Supplement: curcumin; Dietary Supplement: Curcumin conjugated with plant exosomes; Other: No intervention
Sponsors: James Graham Brown Cancer Center; James Graham Brown Cancer Center
Recruiting - verified September 2011 - Condition: Alcohol or Other Drugs Effects
Interventions: Drug: Alcohol + Caffeine Beverage; Drug: Alcohol + Caffeine-placebo
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute on Drug Abuse (NIDA)
Recruiting - verified January 2011 - Conditions: Migraine; Pain
Intervention: Drug: Nitrous Oxide
Sponsors: Children's Hospitals and Clinics of Minnesota; Children's Hospitals and Clinics of Minnesota
Recruiting - verified January 2012 - Conditions: Fibromyalgia; Painful Diabetic Peripheral Neuropathy
Interventions: Other: prior authorization; Other: no prior authorization; Other: prior authorization; Other: no prior authorization
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Conditions: Postmenopausal Osteoporosis; Rheumatoid Arthritis
Interventions: Drug: Etanercept; Drug: Denosumab
Sponsors: Amgen; Amgen
Recruiting - verified November 2011 - Condition: Pain
Interventions: Drug: Fentanyl; Drug: Fentanyl; Drug: Oxycodone/acetaminophen; Drug: oxycodone/acetaminophen
Sponsors: University of Oklahoma; Stephen Thomas; University of Oklahoma
Recruiting - verified February 2012 - Conditions: Laceration; Pain
Interventions: Drug: Ibuprofen; Drug: Oxycodone; Other: Placebo
Sponsors: Children's Hospitals and Clinics of Minnesota; Children's Hospitals and Clinics of Minnesota
Not yet recruiting - verified November 2011 - Condition: Fibromyalgia
Interventions: Drug: pregabalin; Drug: placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Conditions: Spinal Stenosis; Inflammation
Intervention:
Sponsors: New York University School of Medicine; New York University School of Medicine; Hospira, Inc.
Recruiting - verified April 2012 - Condition: Post Herpetic Neuralgia
Interventions: Drug: Pregabalin; Drug: placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Condition: Pain
Interventions: Drug: B&O suppository; Other: Control Group
Sponsors: Loyola University; Loyola University
Recruiting - verified September 2011 - Condition: Multiple Myeloma
Interventions: Drug: Curcumin; Other: Placebo
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center; National Institutes of Health (NIH)
Not yet recruiting - verified April 2012 - Conditions: Tonsillitis; Pain
Interventions: Drug: Codeine with acetaminophen; Drug: Tramadol suspension
Sponsors: Children's Hospitals and Clinics of Minnesota; Children's Hospitals and Clinics of Minnesota
Recruiting - verified September 2011 - Conditions: Adult Intracranial Tumor; Adult Solid Tumor
Interventions: Drug: Remifentanil; Drug: Dexmedetomidine
Sponsors: Outcomes Research Consortium; Outcomes Research Consortium
Recruiting - verified August 2011 - Condition: Hepatocellular Carcinoma
Interventions: Drug: Sorafenib; Drug: VT-122 (propranolol plus etodolac); Drug: Placebo
Sponsors: Vicus Therapeutics; Vicus Therapeutics
Recruiting - verified May 2012 - Condition: Acute Migraine
Interventions: Drug: Metoclorpamide; Drug: Ketorolac; Drug: Valproate
Sponsors: Montefiore Medical Center; Montefiore Medical Center
Recruiting - verified April 2012 - Condition: Procedural Sedation
Interventions: Drug: Propofol; Drug: 1:1 Propofol/Ketamine; Drug: 4:1 Propofol/Ketamine
Sponsors: Minneapolis Medical Research Foundation; Minneapolis Medical Research Foundation
Recruiting - verified February 2012 - Conditions: Mesolthelioma; Esophageal Cancer; Lung Cancer
Interventions: Drug: Celecoxib; Drug: ISCOMATRIX (TM) Adjuvant; Biological: Autologous Tumor Cell Vaccine
Sponsors: National Institutes of Health Clinical Center (CC); National Cancer Institute (NCI)
Recruiting - verified January 2012 - Condition: Sedation
Interventions: Procedure: 1:1 ketamine-propofol mixture sedation; Procedure: Propofol Sedation
Sponsors: University of Utah; University of Utah
Recruiting - verified August 2011 - Conditions: Episodic Migraine; Chronic Migraine
Interventions: Drug: Aspirin (acetylsalicylic acid); Drug: Placebo
Sponsors: Swedish Medical Center; Swedish Medical Center; University of Washington; National Headache Foundation; Wadsworth Foundation; Accumetrics, Inc.
Recruiting - verified July 2011 - Conditions: High Risk Polycythemia Vera; High Risk Essential Thrombocythemia
Interventions: Drug: PEGASYS; Drug: Hydroxyurea; Drug: Aspirin
Sponsors: Myeloproliferative Disorders-Research Consortium; Myeloproliferative Disorders-Research Consortium; National Cancer Institute (NCI); Roche Pharma AG
Recruiting - verified December 2011 - Condition: Sleep Disorders
Interventions: Other: Normal saline infusion; Drug: Dexmedetomidine; Drug: Propofol
Sponsors: University of California, San Francisco; University of California, San Francisco; Masimo Labs
Recruiting - verified May 2012 - Conditions: High Risk Polycythemia Vera; High Risk Essential Thrombocythemia
Interventions: Drug: PEGASYS; Drug: Aspirin
Sponsors: Myeloproliferative Disorders-Research Consortium; Myeloproliferative Disorders-Research Consortium; National Cancer Institute (NCI); Roche Pharma AG
Recruiting - verified February 2012 - Condition: Major Depressive Disorder
Intervention: Drug: ketamine
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified April 2012 - Conditions: HIV; AIDS; Opioid Dependence; Drug Dependence
Intervention: Drug: Depot Naltrexone
Sponsors: Yale University; Yale University; Baystate Medical Center
Recruiting - verified August 2011 - Condition: Leukemia
Interventions: Drug: azacitidine; Drug: cytarabine; Drug: etoposide phosphate; Drug: mitoxantrone hydrochloride; Other: laboratory biomarker analysis; Other: pharmacological study
Sponsors: National Cancer Institute (NCI); Arthur G. James Cancer Hospital & Richard J. Solove Research Institute; National Cancer Institute (NCI)
Recruiting - verified May 2012 - Condition: Radiation-induced Dermatitis
Intervention: Drug: Curcumin
Sponsors: University of Rochester; University of Rochester; National Cancer Institute (NCI)
Recruiting - verified March 2012 - Conditions: Low Back Pain; Pain
Interventions: Drug: Analgesic and co-analgesic therapy; Behavioral: Pain self-management/coping skills treatment
Sponsors: Department of Veterans Affairs; Department of Veterans Affairs
Recruiting - verified February 2012 - Condition: Cancer Patients Who Are Undergoing Chemotherapy Treatments and Are Experiencing Cognitive Difficulties.
Interventions: Drug: Ibuprofen; Behavioral: Home-Based Exercise (EXCAP); Drug: Placebo (sugar pill)
Sponsors: University of Rochester; University of Rochester; National Institutes of Health (NIH)
Recruiting - verified August 2011 - Condition: Healthy
Interventions: Other: Saline; Drug: PF-02545920; Other: Ketamine; Drug: PF-02545920; Other: Saline; Other: Placebo; Other: Ketamine; Other: Placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified April 2012 - Condition: Episodic Migraine
Interventions: Other: saline placebo; Drug: Ibuprofen
Sponsors: Thomas Jefferson University; Thomas Jefferson University
Recruiting - verified June 2011 - Conditions: Migraine Disorders; Migraine Headache; Migraine; Acute Migraine
Interventions: Drug: Topical, intra-oral ketoprofen gel; Other: Placebo gel
Sponsors: Behar, Caren, M.D.; Behar, Caren, M.D.
Not yet recruiting - verified October 2010 - Condition: Influenza
Interventions: Drug: Amantadine, Ribavirin, Oseltamivir; Drug: Oseltamivir
Sponsors: National Institute of Allergy and Infectious Diseases (NIAID); National Institute of Allergy and Infectious Diseases (NIAID)
Recruiting - verified April 2012 - Conditions: Congenital Heart Disease; Cardiopulmonary Bypass
Intervention: Drug: Acetaminophen
Sponsors: Vanderbilt University; Vanderbilt University
Recruiting - verified April 2012 - Condition: Head And Neck Cancer
Interventions: Other: Placebo; Drug: Curcumin; Drug: Armodafinil; Drug: Minocycline; Drug: Bupropion
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center; National Cancer Institute (NCI)
Not yet recruiting - verified November 2011 - Conditions: Pro-inflammatory Activity; Immunologic Activity Alteration [PE]
Interventions: Drug: Fentanyl; Other: Cold pressor test; Other: Fentanyl plus cold pressor test
Sponsors: University of California, Los Angeles; University of California, Los Angeles
Recruiting - verified February 2012 - Condition: Spondylitis, Ankylosing
Interventions: Drug: Part I - etoricoxib 60 mg; Drug: Part I - etoricoxib 90 mg; Drug: Part I- naproxen 1000 mg; Drug: Part I - Placebo to etoricoxib 60 mg; Drug: Part I - Placebo to etoricoxib 90 mg; Drug: Part I - Placebo to naproxen 500 mg; Drug: Part II- etoricoxib 60 mg; Drug: Part II- etoricoxib 90 mg; Drug: Part II- naproxen 1000 mg; Drug: Part II - Placebo to etoricoxib 60 mg; Drug: Part II - Placebo to etoricoxib 90 mg; Drug: Part II - Placebo to naproxen 500 mg
Sponsors: Merck; Merck
Recruiting - verified May 2012 - Condition: Arthritis, Rheumatoid
Interventions: Drug: Part 1: Etoricoxib 60 mg; Drug: Part 1: Etoricoxib 90 mg; Drug: Part 2: Etoricoxib 60 mg; Drug: Part 2: Etoricoxib 90 mg; Drug: Part 1: Placebo to Etoricoxib 60 mg; Drug: Part 1: Placebo to Etoricoxib 90 mg; Drug: Part 2: Placebo to Etoricoxib 60 mg; Drug: Part 2: Placebo to Etoricoxib 90 mg
Sponsors: Merck; Merck
Recruiting - verified May 2012 - Condition: Chronic Oral Food Refusal
Interventions: Drug: Amitriptyline 1 mg/kg; Drug: Placebo
Sponsors: University of Kansas; Ann Davis, PhD, MPH, ABPP
Recruiting - verified March 2012 - Condition: Post Operative Pain
Intervention: Drug: oxymorphone HCl
Sponsors: Endo Pharmaceuticals; Endo Pharmaceuticals
Recruiting - verified November 2011 - Condition: Post Operative Pain
Interventions: Drug: Dilaudid PCA; Drug: Dilaudid IV Scheduled
Sponsors: TriHealth Inc.; TriHealth Inc.
Recruiting - verified September 2011 - Conditions: Deep Brain Stimulation (DBS); Blood Flow; Brain Oxygenation
Interventions: Drug: dexmedetomidine; Drug: propofol
Sponsors: Outcomes Research Consortium; Outcomes Research Consortium
Recruiting - verified June 2011 - Conditions: Diarrhea; Gastrointestinal Complications; Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: sulfasalazine; Other: placebo
Sponsors: National Cancer Institute (NCI); North Central Cancer Treatment Group; National Cancer Institute (NCI)
Recruiting - verified April 2012 - Condition: Spinal Cord Injury
Intervention: Drug: Salsalate
Sponsors: University of Miami; University of Miami
Recruiting - verified November 2011 - Condition: Pain
Intervention: Drug: Oxycodone HCl controlled-release tablets
Sponsors: Purdue Pharma LP; Purdue Pharma LP
Recruiting - verified May 2012 - Condition: Acute Gout
Intervention: Drug: ACZ885
Sponsors: Novartis; Novartis Pharmaceuticals
Recruiting - verified April 2012 - Conditions: Pseudophakia; Cataract Surgery
Interventions: Drug: Pred Forte; Drug: Lotemax
Sponsors: Innovative Medical; Innovative Medical
Recruiting - verified October 2011 - Condition: Depression
Interventions: Drug: Placebo infusion; Drug: ibuprofen intravenous
Sponsors: University of Medicine and Dentistry New Jersey; University of Medicine and Dentistry New Jersey
Recruiting - verified December 2011 - Conditions: Cancers; Chronic Pain
Intervention: Device: Implantation of Morphine Sulfate delivring programmable pump
Sponsors: The Alfred E. Mann Foundation for Scientific Research; The Alfred E. Mann Foundation for Scientific Research
Recruiting - verified March 2012 - Condition: Interstitial Cystitis
Interventions: Drug: Dexmedetomidine; Drug: Normal Saline
Sponsors: University of Rochester; University of Rochester
Recruiting - verified August 2011 - Condition: AML
Interventions: Drug: Sirolimus; Drug: MEC (Mitoxantrone, Etoposide, and Cytarabine)
Sponsors: Thomas Jefferson University; Thomas Jefferson University; University of Pennsylvania
Recruiting - verified January 2012 - Condition: Lung Cancer
Interventions: Other: General-epidural anesthesia and analgesia; Other: Balanced general anesthesia and postoperative opioids
Sponsors: Outcomes Research Consortium; Outcomes Research Consortium
Recruiting - verified August 2011 - Conditions: Relapsed Lymphoma; B Cell Non-Hodgkin Lymphoma; Refractory Lymphoma; High Risk Chronic Lymphocytic Leukemia
Interventions: Drug: Rituximab; Biological: Interleukin-2; Biological: Natural killer cells; Drug: Cyclophosphamide; Drug: Methylprednisolone; Drug: Fludarabine
Sponsors: Masonic Cancer Center, University of Minnesota; Masonic Cancer Center, University of Minnesota
Recruiting - verified April 2012 - Conditions: Opioid Related Disorders; Opioid Dependence; Opioid Addiction
Interventions: Drug: Buprenorphine/naloxone; Drug: Clonidine; Drug: Tramadol ER
Sponsors: National Institute on Drug Abuse (NIDA); National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2012 - Condition: Chronic Rhinosinusitis.
Interventions: Drug: Propofol and Remifentanyl; Drug: Sevoflurane and Remifentanyl
Sponsors: The University of Texas Health Science Center, Houston; The University of Texas Health Science Center, Houston
Recruiting - verified February 2012 - Condition: Adenomatous Polyposis Coli
Interventions: Drug: Erlotinib; Drug: Sulindac; Drug: Placebo A; Drug: Placebo B
Sponsors: University of Utah; University of Utah; National Cancer Institute (NCI)
Recruiting - verified September 2011 - Condition: Pain
Intervention: Drug: Ketamine group
Sponsors: Northwestern University; Northwestern University
Recruiting - verified February 2012 - Condition: Treatment Refractory Depression
Interventions: Drug: Ketamine; Drug: Clonidine; Drug: placebo
Sponsors: Washington University School of Medicine; Washington University School of Medicine; University of Miami
Not yet recruiting - verified March 2012 - Conditions: Acute Myeloid Leukemia; Acute Myeloid Leukemia With Multilineage Dysplasia Following; Myelodysplastic Syndrome; Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(15;17)(q22;q12); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Recurrent Adult Acute Myeloid Leukemia; Secondary Acute Myeloid Leukemia
Interventions: Drug: midostaurin, bortezomib,; Drug: mitoxantrone hydrochloride, etoposide, cytarabine, midostaurin, bortezomib
Sponsors: Ohio State University Comprehensive Cancer Center; Ohio State University Comprehensive Cancer Center; Novartis; Millennium Pharmaceuticals, Inc.
Recruiting - verified November 2011 - Condition: Lung Inflammation
Interventions: Drug: Rosiglitazone; Drug: Zileuton; Drug: Rosiglitazone placebo; Drug: Zileuton placebo
Sponsors: Washington University School of Medicine; Washington University School of Medicine; Doris Duke Charitable Foundation
Recruiting - verified July 2011 - Conditions: Low Back Pain; Radiating Pain
Interventions: Other: Entonox; Other: Oxygen
Sponsors: Outcomes Research Consortium; Outcomes Research Consortium
Recruiting - verified August 2011 - Conditions: Cesarean Delivery; Pain Relief; TAP Block
Interventions: Drug: Placebo; Drug: Group 2 - 15mL 0.25% ropivacaine per side; Drug: . Group 3; Drug: 15mL 0.75% ropivacaine per side
Sponsors: Northwestern University; Northwestern University
Recruiting - verified August 2011 - Conditions: Keratoconus; Ectasia; Degeneration
Interventions: Drug: Ciprofloxicine or Vigamox or other.; Drug: Nonsteroidal (Acular, Acuvail, Voltaren Xibrom, etc); Drug: Steroid (FML, Pred Forte, Flarex, etc.)
Sponsors: Innovative Medical; Innovative Medical
Recruiting - verified April 2012 - Condition: Acute Traumatic Pain in Aeromedical Patients
Interventions: Drug: Ketamine; Drug: Fentanyl
Sponsors: University of Utah; University of Utah
Not yet recruiting - verified July 2011 - Condition: Neonatal Abstinence Syndrome
Interventions: Drug: Clonidine; Drug: Phenobarbital
Sponsors: Baystate Medical Center; Baystate Medical Center
Recruiting - verified April 2012 - Condition: Menorrhagia
Interventions: Drug: Estradiol 30 mcg / Levonorgestrel 150 mcg monophasic oral contraceptive pills; Drug: Naproxen sodium pills; Device: Nova Sure Radiofrequency Endometrial Ablation
Sponsors: Mayo Clinic; Mayo Clinic; Hologic, Inc.
Recruiting - verified January 2012 - Condition: Head and Neck Cancer
Intervention: Dietary Supplement: Microgranular Curcumin C3 Complex®
Sponsors: Louisiana State University Health Sciences Center Shreveport; Louisiana State University Health Sciences Center Shreveport; Feist-Weiller Cancer Center at Louisiana State University Health Sciences; National Cancer Institute (NCI)
Recruiting - verified May 2012 - Condition: Coronary Graft Patency
Interventions: Drug: clopidogrel; Drug: sugar pill
Sponsors: Brooke Army Medical Center; Ahmad Slim; Bristol-Myers Squibb
Recruiting - verified February 2012 - Condition: Coronary Artery Disease
Interventions: Drug: adenosine; Drug: regadenoson; Drug: Adenosine
Sponsors: St. Louis University; St. Louis University; University of Florida; Astellas Pharma US, Inc.
Recruiting - verified July 2011 - Condition: Colorectal Cancer
Interventions: Drug: celecoxib; Drug: fluorouracil; Drug: leucovorin calcium; Drug: oxaliplatin; Other: placebo
Sponsors: National Cancer Institute (NCI); Cancer and Leukemia Group B; National Cancer Institute (NCI)
Recruiting - verified February 2012 - Condition: Vaginal Surgery
Interventions: Drug: Belladonna and Opium Suppositories; Drug: Placebo Suppositories
Sponsors: Mayo Clinic; Mayo Clinic
Recruiting - verified August 2011 - Condition: Labor Pain
Interventions: Drug: Morphine; Drug: Saline
Sponsors: Beth Israel Deaconess Medical Center; Beth Israel Deaconess Medical Center
Recruiting - verified June 2011 - Condition: Cervical Radiculopathy
Interventions: Other: Gabapentin and/or Nortriptyline, Physical therapy; Procedure: Epidural Steroid Injections (ESI); Other: Combination treatment
Sponsors: Johns Hopkins University; Johns Hopkins University; Walter Reed Army Medical Center
Recruiting - verified September 2010 - Conditions: Lung Cancer; Esophageal Cancer; Malignant Pleural Mesothelioma; Thymoma; Thymic Carcinoma
Interventions: Biological: Allogeneic Tumor Cell Vaccine (K562); Drug: Celecoxib; Drug: cyclophosphamide
Sponsors: National Institutes of Health Clinical Center (CC); National Cancer Institute (NCI)
Recruiting - verified March 2012 - Condition: Substance Abuse Disorder
Interventions: Behavioral: Low intensity care; Behavioral: Voucher reinforcement
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute on Drug Abuse (NIDA)
Recruiting - verified August 2011 - Conditions: HIV-1 Infection; Neuropathic Pain
Intervention: Drug: pregabalin (Lyrica)
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Condition: Delirium
Interventions: Drug: Clonidine; Drug: Placebo
Sponsors: Memorial Health University Medical Center; Memorial Health University Medical Center
Recruiting - verified August 2011 - Condition: Migraine
Interventions: Drug: sumatriptan/naproxen sodium; Drug: Placebo
Sponsors: Johns Hopkins University; Johns Hopkins University; University of Michigan; University of Toledo Health Science Campus; Dartmouth-Hitchcock Medical Center
Recruiting - verified August 2011 - Condition: Chronic Myelogenous Leukemia
Intervention: Drug: Zileuton
Sponsors: University of Massachusetts, Worcester; University of Massachusetts, Worcester
Recruiting - verified February 2012 - Conditions: Alcohol Withdrawal Delirium; Alcohol Withdrawal Associated Autonomic Hyperactivity; Alcohol Withdrawal Hallucinosis; Alcohol Withdrawal-Induced Delirium Tremens
Interventions: Drug: Dexmedetomidine; Drug: Placebo
Sponsors: Denver Health and Hospital Authority; Denver Health and Hospital Authority
Recruiting - verified April 2012 - Condition: Epilepsy
Intervention: Drug: Intravenous Carbamazepine (IV CBZ)
Sponsors: Lundbeck LLC; Lundbeck LLC; CyDex Pharmaceuticals, Inc.; ICON Clinical Research; Quintiles
Recruiting - verified April 2012 - Condition: Ulcerative Colitis
Interventions: Drug: MMX Mesalamine; Drug: MMX Mesalamine; Drug: MMX Mesalamine
Sponsors: Shire Development LLC; Shire Development LLC
Recruiting - verified April 2012 - Conditions: Stage IIIC Melanoma; Stage IV Melanoma
Intervention: Drug: Denileukin diftitox
Sponsors: Eisai Inc.; Eisai Inc.; PharmaBio Development Inc.
Recruiting - verified May 2012 - Condition: Refractory Partial Epilepsy
Interventions: Drug: Pregabalin; Drug: Pregabalin
Sponsors: Northeast Regional Epilepsy Group; Northeast Regional Epilepsy Group; Pfizer
Recruiting - verified July 2011 - Bortezomib, Mitoxantrone, Etoposide, and Cytarabine in Relapsed or Refractory Acute Myeloid LeukemiaConditions: Adult Acute Megakaryoblastic Leukemia (M7); Adult Acute Minimally Differentiated Myeloid Leukemia (M0); Adult Acute Monoblastic Leukemia (M5a); Adult Acute Monocytic Leukemia (M5b); Adult Acute Myeloblastic Leukemia With Maturation (M2); Adult Acute Myeloblastic Leukemia Without Maturation (M1); Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Adult Acute Myelomonocytic Leukemia (M4); Adult Erythroleukemia (M6a); Adult Pure Erythroid Leukemia (M6b); Recurrent Adult Acute Myeloid Leukemia
Interventions: Drug: bortezomib; Drug: mitoxantrone hydrochloride; Drug: etoposide; Drug: cytarabine; Other: flow cytometry
Sponsors: Case Comprehensive Cancer Center; Case Comprehensive Cancer Center
Recruiting - verified April 2012 - Condition: Sickle Cell Disease
Intervention: Drug: Zileuton
Sponsors: Children's Hospital Medical Center, Cincinnati; Children's Hospital Medical Center, Cincinnati
Recruiting - verified January 2012 - Condition: Vulvodynia
Intervention: Drug: Gabapentin
Sponsors: University of Tennessee; University of Tennessee; University of Tennessee Health Science Center
Not yet recruiting - verified November 2011 - Conditions: Pain; Ventilatory Depression
Intervention: Drug: hydromorphone
Sponsors: Northwestern University; Northwestern University
Recruiting - verified February 2012 - Condition: Seizure Disorders
Intervention: Drug: Dexmedetomidine
Sponsors: University of California, San Francisco; University of California, San Francisco
Recruiting - verified June 2011 - Condition: Chronic Pain
Interventions: Drug: Extended Release Oxycodone - Crossover Period I; Drug: Immediate release oxycodone - Crossover period 2; Device: Actigraphy analysis; Device: Portable polysomnography
Sponsors: University of Rochester; University of Rochester
Recruiting - verified August 2011 - Condition: Pain
Interventions: Drug: Saline; Drug: Ketamine continuous infusion
Sponsors: Northwestern University; Northwestern University
Recruiting - verified February 2012 - Condition: Pain
Interventions: Drug: Placebo administration; Drug: Dexmedetomidine administration
Sponsors: Northwestern University; Northwestern University
Recruiting - verified February 2012 - Conditions: Ovarian Cancer; Fallopian Tube Cancer; Primary Peritoneal Cancer; Breast Cancer
Interventions: Drug: Fludarabine; Drug: Cyclophosphamide; Drug: Cyclosporine; Biological: Natural killer cells; Drug: IL-2; Drug: Methylprednisolone; Drug: Methylprednisolone; Drug: Interleukin-2
Sponsors: Masonic Cancer Center, University of Minnesota; Masonic Cancer Center, University of Minnesota
Recruiting - verified March 2012 - Conditions: Chemotherapeutic Agent Toxicity; Colorectal Cancer; Neuropathy; Neurotoxicity
Interventions: Drug: calcium gluconate; Drug: magnesium sulfate; Other: placebo
Sponsors: National Cancer Institute (NCI); North Central Cancer Treatment Group; National Cancer Institute (NCI)
Recruiting - verified May 2012 - Condition: Obsessive-Compulsive Disorder
Interventions: Drug: Ketamine infusion; Other: Saline
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute
Recruiting - verified December 2011 - Condition: Malignant Pleural Mesothelioma
Interventions: Drug: NGR-hTNF plus Best Investigator Choice (BIC); Drug: Placebo plus Best Investigator Choice (BIC)
Sponsors: MolMed S.p.A.; MolMed S.p.A.
Recruiting - verified December 2011 - Condition: Overactive Bladder
Interventions: Drug: Trospium Chloride (Sanctura XR); Drug: Over-encapsulated Placebo
Sponsors: Allergan; Allergan
Recruiting - verified March 2012 - Condition: Chronic Beryllium Disease
Interventions: Drug: Mesalamine; Drug: Placebo
Sponsors: National Jewish Health; National Jewish Health
Recruiting - verified December 2011 - Condition: Sickle Cell Disease
Intervention: Drug: Lexiscan
Sponsors: Dana-Farber Cancer Institute; Dana-Farber Cancer Institute; Brigham and Women's Hospital; Children's Hospital Boston; Washington University School of Medicine; LaJolla Institute for Allergy and Immunology; National Heart, Lung, and Blood Institute (NHLBI); Astellas Pharma Global Development, Inc.
Recruiting - verified June 2011 - Condition: Cardiovascular Disease
Interventions: Drug: Active Clonidine; Drug: Placebo Clonidine; Drug: Active ASA; Drug: Placebo ASA
Sponsors: McMaster University; Hamilton Health Sciences Corporation; McMaster University
Recruiting - verified December 2011 - Conditions: Anaplastic Astrocytoma; Anaplastic Ependymoma; Anaplastic Meningioma; Anaplastic Oligodendroglioma; Brain Stem Glioma; Ependymoblastoma; Giant Cell Glioblastoma; Glioblastoma; Gliosarcoma; Grade III Meningioma; Meningeal Hemangiopericytoma; Mixed Glioma; Pineal Gland Astrocytoma; Brain Tumor
Interventions: Biological: therapeutic allogeneic lymphocytes; Biological: aldesleukin; Other: laboratory biomarker analysis; Procedure: positron emission tomography
Sponsors: City of Hope Medical Center; City of Hope Medical Center
Recruiting - verified November 2011 - Condition: Postoperative Pain
Intervention: Drug: cyclobenzaprine
Sponsors: NorthShore University HealthSystem Research Institute; NorthShore University HealthSystem Research Institute
Recruiting - verified March 2012 - Condition: Malignant Melanoma
Interventions: Drug: Interleukin-2; Drug: Interleukin-2; Drug: Temozolomide
Sponsors: Penn State University; Penn State University
Recruiting - verified May 2012 - Condition: Parkinson's Disease
Interventions: Drug: Amantadine; Drug: Placebo
Sponsors: Rush University Medical Center; Rush University Medical Center; Michael J. Fox Foundation for Parkinson's Research
Recruiting - verified July 2011 - Condition: Pulmonary Hypertension
Intervention: Drug: Dexmedetomidine
Sponsors: Children's Hospital of Philadelphia; Aruna Nathan; Children's Hospital of Philadelphia
Recruiting - verified May 2012 - Condition: Drug Dependence
Intervention: Drug: 2-4 of the drugs listed below
Sponsors: University of Arkansas; University of Arkansas; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Conditions: Pain; Breast Cancer; Lung Cancer
Interventions: Drug: Gabapentin; Drug: Placebo
Sponsors: Stanford University; Stanford University
Recruiting - verified September 2011 - Condition: Migraine Disorders
Interventions: Drug: Sumatriptan; Drug: Naratriptan; Drug: Sumatriptan-naproxen combination
Sponsors: GlaxoSmithKline; GlaxoSmithKline
Recruiting - verified February 2012 - Condition: Opioid Dependence
Interventions: Drug: Memantine; Drug: Memantine; Drug: Placebo
Sponsors: University of Massachusetts, Worcester; University of Massachusetts, Worcester; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Condition: Post-Traumatic Headache
Interventions: Drug: sumatriptan/naproxen sodium; Drug: Placebo
Sponsors: Cady, Roger, M.D.; Cady, Roger, M.D.; GlaxoSmithKline
Recruiting - verified April 2012 - Condition: Healthy
Interventions: Procedure: Aspirin ingestion followed by doing a Bleeding Volume Test; Procedure: Gatorade Placebo followed by Bleeding Volume Test.
Sponsors: Klein, Jeffrey A., M.D.; Klein, Jeffrey A., M.D.
Recruiting - verified June 2011 - Condition: Lung Cancer
Interventions: Drug: carboplatin; Drug: celecoxib; Drug: gemcitabine hydrochloride; Drug: pemetrexed disodium; Other: placebo
Sponsors: National Cancer Institute (NCI); Cancer and Leukemia Group B; National Cancer Institute (NCI)
Recruiting - verified February 2012 - Condition: Diverticulitis
Interventions: Drug: Mesalazine; Drug: Mesalazine; Drug: Placebo
Sponsors: Dr. Falk Pharma GmbH; Dr. Falk Pharma GmbH
Recruiting - verified January 2012 - Conditions: Functional Disability; Dementia; Heart Disease; Stroke; Cancer; Bleeding
Interventions: Drug: 100 mg enteric-coated aspirin; Drug: Placebo
Sponsors: Minneapolis Medical Research Foundation; Minneapolis Medical Research Foundation; National Health and Medical Research Council, Australia; Bayer; Monash University; Berman Center for Outcomes and Clinical Research
Recruiting - verified July 2011 - Condition: Renal Cell Carcinoma
Intervention: Drug: Aldesleukin
Sponsors: Roswell Park Cancer Institute; Roswell Park Cancer Institute
Recruiting - verified January 2012 - Condition: Sickle Cell Disease
Intervention: Drug: sodium nitrite injection, usp
Sponsors: Children's Hospital Los Angeles; Children's Hospital Los Angeles; Hope Pharmaceuticals
Recruiting - verified November 2009 - Condition: Opioid Dependence
Interventions: Drug: injectable naltrexone plus dronabinol; Drug: Naltrexone plus placebo
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute on Drug Abuse (NIDA)
Recruiting - verified May 2012 - Conditions: Carcinoma, Intraductal, Noninfiltrating; DCIS; Ductal Carcinoma In Situ
Interventions: Drug: Chloroquine Standard Dose (500mg/week); Drug: Chloroquine Low Dose (250mg/week); Procedure: Breast Biopsy
Sponsors: Inova Health Care Services; Inova Health Care Services; George Mason University; Department of Defense; U.S. Army Medical Research and Materiel Command
Recruiting - verified March 2012 - Conditions: Cannabis Dependence; Marijuana Dependence
Interventions: Drug: Lofexidine and Dronabinol; Drug: Placebo
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2012 - Condition: Fibromyalgia
Intervention: Drug: pregabalin
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Condition: Fibromyalgia
Interventions: Drug: placebo; Drug: pregabalin (Lyrica)
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Condition: Headache
Interventions: Drug: Metoclopramide; Drug: Ketorolac
Sponsors: Montefiore Medical Center; Montefiore Medical Center
Recruiting - verified April 2012 - Conditions: Neoplasms; Constipation; Opioid-Related Disorders
Intervention: Drug: Methylnaltrexone bromide
Sponsors: University of Vermont; University of Vermont
Recruiting - verified March 2012 - Condition: To Evaluate Two Paradigms for Simultaneous Assessment of Hepatic and Intestinal CYP3A Activity
Intervention: Drug: of d0- and d3-alfentanil
Sponsors: Washington University School of Medicine; Washington University School of Medicine
Recruiting - verified February 2012 - Condition: Idiopathic Intracranial Hypertension
Interventions: Drug: Acetazolamide; Drug: Placebo; Behavioral: Formal weight loss counselling program
Sponsors: St. Luke's-Roosevelt Hospital Center; St. Luke's-Roosevelt Hospital Center; National Eye Institute (NEI); University of Rochester; University of Iowa; University of California, Davis
Recruiting - verified May 2012 - Conditions: Keratoconus; Ectasia; Degeneration
Interventions: Drug: Ciprofloxicine or Vigamox or other.; Drug: Nonsteroidal (Acular, Voltaren Xibrom, etc); Drug: Steroid (FML, Pred Forte, Flarex, etc.)
Sponsors: Innovative Medical; Innovative Medical
Recruiting - verified February 2012 - Condition: Hot Flashes
Intervention: Drug: Gabapentin
Sponsors: Abramson Cancer Center of the University of Pennsylvania; Abramson Cancer Center of the University of Pennsylvania
Recruiting - verified May 2012 - Lymphodepletion Plus Adoptive Cell Transfer With High Dose IL-2 in Patients With Metastatic MelanomaCondition: Metastatic Melanoma
Interventions: Procedure: Surgery; Drug: Administration of Lymphodepletion; Other: Adoptive Cell Transfer; Drug: High Dose IL-2
Sponsors: H. Lee Moffitt Cancer Center and Research Institute; H. Lee Moffitt Cancer Center and Research Institute
Recruiting - verified January 2012 - Condition: Fever
Interventions: Drug: ibuprofen; Drug: acetaminophen
Sponsors: Cumberland Pharmaceuticals; Cumberland Pharmaceuticals
Recruiting - verified March 2012 - Condition: Ambulatory Surgery
Interventions: Drug: Dexmedetomidine infusion; Drug: propofol
Sponsors: University of Medicine and Dentistry New Jersey; University of Medicine and Dentistry New Jersey
Recruiting - verified August 2011 - Condition: Opiate Addiction
Interventions: Drug: Buprenorphine/naloxone; Drug: Naltrexone
Sponsors: State University of New York at Buffalo; State University of New York at Buffalo
Recruiting - verified February 2011 - Condition: Sedation
Interventions: Drug: Propofol; Drug: Alfentanil; Drug: Nitrous Oxide
Sponsors: Minneapolis Medical Research Foundation; Minneapolis Medical Research Foundation
Recruiting - verified February 2012 - Condition: Sedation
Interventions: Drug: propofol; Drug: alfentanil
Sponsors: Minneapolis Medical Research Foundation; Minneapolis Medical Research Foundation
Recruiting - verified February 2012 - Condition: High Risk Non-Hodgkin's Lymphoma
Interventions: Biological: Rituximab; Biological: Interleukin-2
Sponsors: Thomas Jefferson University; Thomas Jefferson University
Recruiting - verified April 2012 - Condition: Opiate Dependence
Intervention: Behavioral: Linkage
Sponsors: Butler Hospital; Butler Hospital; Boston Medical Center
Recruiting - verified March 2012 - Condition: Familial Adenomatous Polyposis
Interventions: Drug: eflornithine (DFMO); Drug: acetylsalicylic acid (aspirin); Other: placebo; Other: laboratory biomarker analysis; Other: gene expression analysis; Other: telephone-based intervention; Other: immunohistochemistry staining method; Other: reverse transcriptase-polymerase chain reaction; Other: protein expression analysis
Sponsors: Mayo Clinic; Mayo Clinic
Recruiting - verified March 2012 - Condition: Glaucoma
Interventions: Drug: Prednisolone 1%; Drug: Diclofenac 0.1%; Drug: Artificial Tears
Sponsors: University of Miami; University of Miami; Bascom Palmer Eye Institute; University of Pittsburgh
Recruiting - verified August 2011 - Conditions: Cannabis Dependence; Cannabis Withdrawal; Cognitive Deficits
Interventions: Drug: gabapentin 1200mg/day; Drug: Placebo
Sponsors: The Scripps Research Institute; The Scripps Research Institute
Recruiting - verified March 2012 - Conditions: Parkinson Disease; Huntington Disease
Intervention: Drug: [123I]MNI-420
Sponsors: Institute for Neurodegenerative Disorders; Institute for Neurodegenerative Disorders
Recruiting - verified February 2012 - Conditions: Lymphoma; B-cell Lymphoma
Interventions: Procedure: Leukapheresis; Procedure: Stem Cell Transplant; Procedure: CD19-specific T Cell Infusion; Drug: IL-2; Drug: Carmustine; Drug: Etoposide; Drug: Cytarabine; Drug: Melphalan; Drug: Rituximab
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center
Recruiting - verified April 2012 - Condition: Cutaneous T-cell Lymphoma
Interventions: Drug: Curcumin (Turmeric); Behavioral: Questionnaires; Other: Photos
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center
Not yet recruiting - verified May 2012 - Conditions: Schizophrenia; Mental Disorders; Psychotic Disorders
Interventions: Drug: THC and Iomazenil; Drug: Placebo (control)
Sponsors: Yale University; Yale University
Recruiting - verified July 2011 - Condition: Mouth Neoplasms
Interventions: Drug: 1,25-dihydroxyvitamin D3; Drug: celecoxib; Drug: 1,25-dihydroxyvitamin D3 + celecoxib
Sponsors: Department of Veterans Affairs; Department of Veterans Affairs
Recruiting - verified March 2012 - Condition: Postoperative Pain
Interventions: Drug: Gabapentin; Drug: pregabalin
Sponsors: Loma Linda University; Loma Linda University
Recruiting - verified March 2012 - Condition: Spastic Cerebral Palsy
Interventions: Drug: Extended-release Epidural morphine (EREM) 80; Drug: Extended-release Epidural Morphine (EREM) 120; Drug: Control: Saline
Sponsors: Washington University School of Medicine; Washington University School of Medicine
Recruiting - verified August 2011 - Conditions: Schizophrenia; Dual Diagnosis; Schizoaffective Disorder; Psychotic Disorder; Cannabis Use Disorder
Interventions: Drug: Dronabinol; Drug: Cannabis
Sponsors: Dartmouth-Hitchcock Medical Center; Dartmouth-Hitchcock Medical Center; National Institute on Drug Abuse (NIDA); Indiana University; Columbia University; University of Vermont; University of Massachusetts, Worcester
Recruiting - verified January 2012 - Conditions: Leukemia; Acute Lymphoblastic Leukemia
Intervention: Drug: Dasatinib, Mitoxantrone, Cytarabine
Sponsors: Memorial Sloan-Kettering Cancer Center; Memorial Sloan-Kettering Cancer Center; Bristol-Myers Squibb
Recruiting - verified January 2012 - Conditions: Advanced Non-small Cell Lung Cancer; Postmenopausal Women
Interventions: Drug: fulvestrant (Faslodex); Drug: anastrozole (Arimidex); Drug: Bevacizumab (Avastin); Drug: Best standard of care
Sponsors: University of Pittsburgh; University of Pittsburgh
Recruiting - verified January 2012 - Condition: Alcohol Dependence
Interventions: Drug: Pregabalin; Drug: Duloxetine; Behavioral: Standardized behavioral therapy; Behavioral: Standardized behavioral therapy; Drug: Placebo; Behavioral: Standardized behavioral therapy
Sponsors: The Scripps Research Institute; The Scripps Research Institute; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified June 2011 - Condition: Pain
Intervention: Other: perplexing and prevalent problem of chronic pain
Sponsors: Department of Veterans Affairs; Department of Veterans Affairs
Recruiting - verified December 2011 - Condition: Opiate Addiction
Interventions: Other: Brief Intervention with Buprenorphine initiation; Behavioral: Brief Intervention
Sponsors: Yale University; Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified December 2011 - Condition: Metastatic Renal Cell Carcinoma
Interventions: Biological: DC vaccine; Drug: Bevacizumab; Biological: IL-2; Biological: IFN
Sponsors: Dartmouth-Hitchcock Medical Center; Dartmouth-Hitchcock Medical Center; National Cancer Institute (NCI)
Recruiting - verified October 2011 - Conditions: Lumbar Radicular Pain; Failed Back Surgery Syndrome; Spinal Stenosis; Herniated Disc
Interventions: Drug: Pregabalin; Drug: Sugar Pill
Sponsors: Northwestern University; Northwestern University
Recruiting - verified March 2012 - Condition: Leukemia, Myeloid, Acute
Interventions: Drug: G-CSF; Drug: Plerixafor; Drug: Mitoxantrone; Drug: Etoposide; Drug: Cytarabine
Sponsors: Washington University School of Medicine; Washington University School of Medicine
Recruiting - verified October 2011 - Condition: Arthroplasty, Replacement, Knee
Interventions: Drug: Depodur; Procedure: sciatic nerve block
Sponsors: University of Louisville; University of Louisville; EKR Therapeutics, Inc
Recruiting - verified August 2011 - Condition: Migraine With Aura
Interventions: Drug: sumatriptan with naprosyn; Drug: placebo
Sponsors: Dent Neurologic Institute; Dent Neurologic Institute
Recruiting - verified February 2012 - Conditions: Fracture; Pain, Postoperative
Interventions: Drug: Methadone; Drug: Morphine
Sponsors: University of Louisville; University of Louisville
Recruiting - verified August 2011 - Condition: Marijuana Abuse
Intervention: Drug: bupropion, diazepam, dronabinol, ramelteon (Investigational Drug)
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute on Drug Abuse (NIDA)
Recruiting - verified May 2009 - Condition: Diabetes Mellitus, Type I
Interventions: Biological: Purified Pancreatic Islets; Drug: Etanercept
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified January 2012 - Conditions: Recurrent Melanoma; Stage IV Melanoma
Interventions: Biological: ipilimumab; Drug: cyclophosphamide; Procedure: biopsy; Biological: aldesleukin; Other: immunohistochemistry staining method; Genetic: polymerase chain reaction; Other: immunoenzyme technique; Biological: therapeutic allogeneic cytotoxic T lymphocytes
Sponsors: Fred Hutchinson Cancer Research Center; Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium; National Cancer Institute (NCI)
Recruiting - verified February 2012 - Condition: Migraine Headache
Interventions: Drug: Treximet (Imitrex + naproxen sodium); Other: Inert Placebo
Sponsors: University of Toledo Health Science Campus; University of Toledo Health Science Campus; GlaxoSmithKline
Recruiting - verified January 2012 - Condition: Leukemia
Interventions: Drug: arsenic trioxide; Drug: cytarabine; Drug: idarubicin; Drug: mercaptopurine; Drug: methotrexate; Drug: mitoxantrone hydrochloride; Drug: tretinoin; Genetic: cytogenetic analysis; Genetic: polymerase chain reaction; Other: laboratory biomarker analysis
Sponsors: National Cancer Institute (NCI); Children's Oncology Group; National Cancer Institute (NCI)
Recruiting - verified May 2012 - Condition: Leprosy
Intervention: Drug: clofazamine
Sponsors: Kaiser Permanente; Kaiser Permanente; National Hansen's Disease Program
Available - verified April 2012 - Condition: Renal Injury
Intervention: Other: Attenuated bedrest
Sponsors: Children's Mercy Hospital Kansas City; Children's Mercy Hospital Kansas City; Phoenix Children's Hospital
Recruiting - verified December 2011 - Conditions: HIV; Substance Abuse; HIV Infections
Interventions: Behavioral: Intensive Case Management; Drug: Buprenorphine; Behavioral: Money Management
Sponsors: Yale University; Yale University
Recruiting - verified June 2011 - Conditions: Mucocutaneous Lymph Node Syndrome; Kawasaki Disease
Interventions: Drug: Etanercept; Drug: Placebo
Sponsors: Seattle Children's Hospital; Michael Portman; FDA Office of Orphan Products Development; Amgen
Recruiting - verified April 2012 - Conditions: Psoriasis; Melanoma; Non-melanoma Skin Cancer
Intervention: Drug: etanercept
Sponsors: University of Alabama at Birmingham; University of Alabama at Birmingham; Amgen
Recruiting - verified August 2011 - Condition: Rheumatoid Arthritis
Interventions: Drug: Etanercept; Drug: Adalimumab
Sponsors: National Institute of Allergy and Infectious Diseases (NIAID); National Institute of Allergy and Infectious Diseases (NIAID)
Recruiting - verified May 2012 - Conditions: Pain; Chronic Pain; Hyperalgesia
Intervention: Drug: Ketamine
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified March 2012 - Conditions: Tonsillectomy; Adenoidectomy; Pharmacokinetics
Intervention:
Sponsors: Children's Hospital of Philadelphia; Children's Hospital of Philadelphia; Children's Anesthesiology Associates, Ltd.
Not yet recruiting - verified February 2012 - Condition: Liver Failure
Interventions: Behavioral: Focus Groups; Behavioral: Personal Interviews
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center
Recruiting - verified April 2012 - Condition: HIV Infections
Interventions: Drug: Chloroquine; Drug: Placebo
Sponsors: AIDS Clinical Trials Group; AIDS Clinical Trials Group; National Institute of Allergy and Infectious Diseases (NIAID)
Recruiting - verified February 2012 - Condition: Cocaine Dependence
Interventions: Drug: Galantamine; Drug: placebo
Sponsors: Yale University; Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2012 - Condition: Arthritis, Juvenile Rheumatoid
Interventions: Drug: Celecoxib; Drug: Naproxen
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Condition: Severe Combined Immunodeficiency
Intervention: Biological: ADA gene transfer
Sponsors: University of California, Los Angeles; University of California, Los Angeles; FDA Office of Orphan Products Development; National Institutes of Health (NIH)
Recruiting - verified June 2011 - Conditions: Bladder Cancer; Cervical Cancer; Esophageal Cancer; Gastric Cancer; Head and Neck Cancer; Kidney Cancer; Leukemia; Liver Cancer; Lung Cancer; Pancreatic Cancer; Tobacco Use Disorder
Interventions: Drug: nicotine; Drug: varenicline; Other: placebo
Sponsors: Butler Hospital; Butler Hospital; National Cancer Institute (NCI)
Recruiting - verified March 2012 - Condition: Breast Cancer
Interventions: Biological: allogeneic large multivalent immunogen breast cancer vaccine; Biological: aldesleukin
Sponsors: Masonic Cancer Center, University of Minnesota; Masonic Cancer Center, University of Minnesota
Recruiting - verified May 2012 - Conditions: Cocaine Dependence; Cocaine-Related Disorders; Opioid-Related Disorders
Interventions: Drug: Airipiprazole; Drug: Placebo
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified July 2011 - Conditions: Brain Injury; Aggression
Interventions: Drug: Amantadine Hydrochloride; Drug: Placebo
Sponsors: Carolinas Healthcare System; Carolinas Healthcare System; Indiana University; University of Washington; The Institute for Rehabilitation and Research; Spaulding Rehabilitation Hospital; Ohio State University; Mount Sinai School of Medicine
Recruiting - verified February 2012 - Condition: Otitis Media
Interventions: Drug: dexmedetomidine; Drug: saline
Sponsors: Ochsner Health System; Ochsner Health System
Recruiting - verified October 2011 - Conditions: Wiskott-Aldrich Syndrome (WAS); X-linked Thrombocytopenia
Intervention: Drug: Interleukin-2
Sponsors: Children's Hospital of Philadelphia; Jordan Orange
Recruiting - verified January 2012 - Condition: Sickle Cell Disease
Interventions: Drug: Morphine; Drug: Methadone; Drug: Methadone
Sponsors: Washington University School of Medicine; Washington University School of Medicine
Recruiting - verified February 2012 - Conditions: Ischemia; Coronary Disease
Intervention:
Sponsors: University of Connecticut Health Center; University of Connecticut Health Center; Department of Defense
Recruiting - verified July 2011 - Conditions: Pain; Hip Fractures
Intervention: Procedure: Femoral Nerve Block
Sponsors: Mount Sinai School of Medicine; Mount Sinai School of Medicine; National Institute on Aging (NIA)
Recruiting - verified February 2012 - Conditions: Stress Disorders, Post-Traumatic; PTSD; Depression; Anxiety Disorder
Interventions: Drug: Midazolam; Drug: Ketamine
Sponsors: Mount Sinai School of Medicine; Dennis Charney; Department of Defense
Recruiting - verified March 2012 - Conditions: Chronic Pain; Osteoarthritis
Intervention: Drug: MS Contin
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Nursing Research (NINR)
Recruiting - verified June 2011 - Condition: Bronchitis
Intervention: Drug: Etanercept inhibition of ozone-induced airway hyper-responsiveness.
Sponsors: National Institute of Environmental Health Sciences (NIEHS); National Institute of Environmental Health Sciences (NIEHS)
Recruiting - verified August 2009 - Condition: Patent Ductus Arteriosus
Interventions: Other: feeding; Other: fasting
Sponsors: University of California, San Francisco; University of California, San Francisco
Recruiting - verified April 2012 - Condition: Metastatic Pancreatic Cancer
Intervention: Drug: Ontak
Sponsors: Loyola University; Loyola University; Riveria Country Club Organization; Eisai Inc.
Recruiting - verified September 2011 - Condition: Acute Graft Versus Host Disease
Intervention: Drug: Etanercept (Enbrel)
Sponsors: University of Michigan Cancer Center; University of Michigan Cancer Center
Recruiting - verified September 2011 - Conditions: Anaplastic Large Cell Lymphoma; Cutaneous B-cell Non-Hodgkin Lymphoma; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Intraocular Lymphoma; Nodal Marginal Zone B-cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Adult Grade III Lymphomatoid Granulomatosis; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Marginal Zone Lymphoma; Small Intestine Lymphoma; Splenic Marginal Zone Lymphoma; Testicular Lymphoma; Waldenstrom Macroglobulinemia
Interventions: Biological: DI-Leu16-IL2 immunocytokine; Biological: rituximab; Other: flow cytometry; Other: immunohistochemistry staining method; Other: pharmacological study; Other: laboratory biomarker analysis; Other: enzyme-linked immunosorbent assay; Genetic: reverse transcriptase-polymerase chain reaction
Sponsors: City of Hope Medical Center; City of Hope Medical Center
Recruiting - verified March 2012 - Conditions: Leukemia; Chronic Lymphocytic Leukemia
Intervention: Drug: 8-Chloro-Adenosine
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center; National Cancer Institute (NCI); FDA Office of Orphan Products Development
Recruiting - verified March 2012 - Condition: Kidney Stones
Interventions: Drug: Alfuzosin; Drug: nifedipine; Drug: doxazosin; Drug: prazosin
Sponsors: United States Naval Medical Center, San Diego; United States Naval Medical Center, San Diego
Recruiting - verified April 2012 - Condition: Non-Hodgkin's Lymphoma
Interventions: Drug: Etoposide, carboplatin, ifosfamide; Drug: Rituximab, Ifosfamide, Etoposide, Carboplatin; Drug: Rituximab, Ifosfamide, Etoposide, Carboplatin, Stem Cell Collection, Mitoxantrone, Cyclophosphamide and etoposide, Carmustine
Sponsors: Memorial Sloan-Kettering Cancer Center; Memorial Sloan-Kettering Cancer Center; Genentech; Columbia University
Recruiting - verified January 2012 - Conditions: Cannabis; Psychotic Disorders
Interventions: Drug: THC; Drug: Placebo
Sponsors: Yale University; Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified July 2011 - Condition: Ovarian Cancer
Interventions: Biological: Ontak DC; Biological: DC vaccination; Drug: Ontak
Sponsors: Loyola University; Loyola University
Recruiting - verified September 2011 - Conditions: Heroin Dependence; Opioid-Related Disorders; Cocaine Abuse or Dependence
Intervention:
Sponsors: Wayne State University; Wayne State University; National Institute on Drug Abuse (NIDA)
Recruiting - verified October 2011 - Conditions: Heroin Dependence; Opioid-Related Disorders
Intervention:
Sponsors: Wayne State University; Wayne State University; National Institute on Drug Abuse (NIDA)
Recruiting - verified October 2011 - Condition: Colon Cancer
Interventions: Procedure: Regional anesthesia and analgesia; Drug: general anesthesia followed by opioid analgesia
Sponsors: Outcomes Research Consortium; Outcomes Research Consortium
Recruiting - verified May 2012 - Condition: Multiple Sclerosis
Interventions: Drug: Smoked Cannabis; Drug: Smoked Cannabis and oral marinol; Drug: Placebo
Sponsors: University of California, Davis; University of California, Davis; National Multiple Sclerosis Society
Recruiting - verified March 2012 - Condition: Type 1 Diabetes Mellitus
Intervention: Drug: Islets of Langerhans transplantation
Sponsors: University of Illinois; University of Illinois
Recruiting - verified August 2011 - Condition: COMT Gene Polymorphism
Intervention: Drug: delta 9 tetrahydrocannabinol
Sponsors: Yale University; Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified July 2011 - Condition: Psoriasis
Interventions: Procedure: Narrow band (310-312 nm) ultraviolet light B phototherapy; Drug: etanercept
Sponsors: University of California, San Francisco; University of California, San Francisco
Recruiting - verified February 2012 - Condition: Opioid-Induced Constipation
Interventions: Drug: Methylnaltrexone bromide; Drug: Placebo
Sponsors: Salix Pharmaceuticals; Salix Pharmaceuticals; Progenics Pharmaceuticals, Inc.
Recruiting - verified January 2012 - Condition: Opioid-Induced Constipation
Intervention: Drug: Methylnaltrexone bromide
Sponsors: Salix Pharmaceuticals; Salix Pharmaceuticals; Progenics Pharmaceuticals, Inc.
Recruiting - verified January 2012 - Condition: Breast Cancer
Interventions: Biological: Gene Modified T Cells; Biological: Gene Modified T Cells and Interleukin 2
Sponsors: Roger Williams Medical Center; Roger Williams Medical Center; Department of Defense
Recruiting - verified January 2012 - Conditions: Breast Cancer; Depression; Hot Flashes; Psychosocial Effects of Cancer and Its Treatment
Interventions: Drug: citalopram hydrobromide; Drug: escitalopram oxalate; Drug: gabapentin; Drug: sertraline hydrochloride; Drug: tamoxifen citrate; Drug: venlafaxine; Genetic: molecular genetic technique; Other: high performance liquid chromatography; Other: laboratory biomarker analysis; Other: pharmacological study; Procedure: adjuvant therapy
Sponsors: Mayo Clinic; Mayo Clinic; National Cancer Institute (NCI)
Recruiting - verified April 2012 - Condition: Constipation
Interventions: Drug: Lubiprostone; Drug: Senna
Sponsors: Rehabilitation Institute of Chicago; Rehabilitation Institute of Chicago; Takeda Pharmaceuticals North America, Inc.
Recruiting - verified September 2011 - Conditions: Acute Lymphoblastic Leukemia; Chronic Myelogenous Leukemia; Juvenile Myelomonocytic Leukemia; Myelodysplastic Syndrome; Non-Hodgkin's Lymphoma
Interventions: Other: NK Cell Infusion; Biological: Immunotherapy; Device: Miltenyi Biotec CliniMACS device; Drug: Interleukin-2 (IL-2); Drug: Clofarabine; Drug: Cyclophosphamide; Drug: Etoposide
Sponsors: St. Jude Children's Research Hospital; St. Jude Children's Research Hospital
Recruiting - verified December 2011 - Condition: Chronic Pain
Intervention:
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified January 2012 - Condition: Ulcerative Colitis
Intervention: Drug: mesalamine
Sponsors: University of Pennsylvania; University of Pennsylvania; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Shire Development LLC
Recruiting - verified December 2011 - Condition: Familial Adenomatous Polyposis
Interventions: Dietary Supplement: curcumin; Drug: placebo
Sponsors: Johns Hopkins University; Johns Hopkins University
Recruiting - verified March 2012 - Conditions: Leukemia, Myeloid, Acute; Leukemia, Lymphocytic, Acute, T-Cell; Juvenile Myelomonocytic Leukemia Lymphoblastic; T-cell Lymphoblastic Lymphoma; Myelodysplastic Syndrome
Interventions: Procedure: Haploidentical donor derived natural killer cell infusion; Drug: Chemotherapy (Cyclophosphamide, Fludarabine, Interleukin-2, Mesna); Device: CliniMACS
Sponsors: St. Jude Children's Research Hospital; St. Jude Children's Research Hospital; National Cancer Institute (NCI); Assisi Foundation
Recruiting - verified March 2012 - Condition: Graft Versus Host Disease
Interventions: Procedure: stem cell transplant; Drug: tacrolimus (standard GVHD prophylaxis); Drug: mycophenolate (standard GVHD prophylaxis); Drug: etanercept; Drug: methoxsalen
Sponsors: University of Michigan Cancer Center; University of Michigan Cancer Center; Therakos; Amgen
Recruiting - verified November 2011 - Condition: Substance-related Discorder
Interventions: Drug: Nicotine; Drug: Carfentanil
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA); Johns Hopkins University
Recruiting - verified June 2011 - Conditions: Coronary Artery Disease; Overweight
Interventions: Drug: Salsalate; Drug: Placebo
Sponsors: Joslin Diabetes Center; Allison Goldfine; Beth Israel Deaconess Medical Center; Tufts Medical Center
Recruiting - verified March 2012 - Condition: Alcoholism
Interventions: Drug: THC; Drug: Placebo
Sponsors: Yale University; Yale University; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified April 2012 - Condition: Traumatic Brain Injury
Interventions: Drug: Carbamazepine; Drug: Placebo
Sponsors: Carolinas Healthcare System; Carolinas Healthcare System; U.S. Department of Education
Recruiting - verified February 2012 - Conditions: Diabetic Neuropathic Pain; Chronic Low Back Pain
Interventions: Drug: donepezil; Drug: duloxetine; Drug: donepezil 2.5 mg and duloxetine 30mg; Drug: placebo; Drug: gabapentin
Sponsors: Wake Forest University; Wake Forest University; National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified February 2012 - Condition: Chronic Pain
Intervention:
Sponsors: Rush University Medical Center; Asokumar Buvanendran
Recruiting - verified April 2012 - Conditions: Opiate Dependence; Chronic Pain
Interventions: Behavioral: CBT; Drug: Buprenorphine; Other: Educational Counseling; Other: Physician Management
Sponsors: Yale University; Yale University
Recruiting - verified May 2012 - Condition: Adenomatous Polyposis Coli
Interventions: Drug: Celecoxib; Drug: Placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Condition: Ventricular Tachycardia
Interventions: Drug: clonidine; Drug: metoprolol
Sponsors: University of Iowa; University of Iowa; National Center for Research Resources (NCRR)
Recruiting - verified December 2007 - Condition: Melanoma
Interventions: Drug: hu14.18-IL2; Drug: hu14.18-IL2
Sponsors: University of Wisconsin, Madison; University of Wisconsin, Madison; National Cancer Institute (NCI); EMD Serono
Recruiting - verified December 2011 - Conditions: Minor Surgical Procedures With Monitored Anesthesia Care.; Driving Performance After Minor Ambulatory Surgery.
Interventions: Other: Control; Drug: Midazolam; Drug: Sufentanil; Drug: Propofol
Sponsors: Rush University Medical Center; Rush University Medical Center
Recruiting - verified April 2012 - Condition: Colorectal Cancer
Intervention: Drug: Aspirin
Sponsors: University of California, Irvine; University of California, Irvine
Recruiting - verified March 2012 - Condition: Recurrent Respiratory Papillomatosis
Interventions: Drug: celebrex (celecoxib); Drug: placebo capsules
Sponsors: North Shore Long Island Jewish Health System; North Shore Long Island Jewish Health System; National Institute on Deafness and Other Communication Disorders (NIDCD)
Recruiting - verified January 2012 - Condition: Atopic Dermatitis
Intervention: Drug: Pimecrolimus
Sponsors: Valeant Pharmaceuticals International, Inc.; Valeant Pharmaceuticals International, Inc.; Clinical Research Computing Unit (University of Pennsylvania)
Recruiting - verified May 2012 - Condition: Cocaine Addictions
Interventions: Drug: sugar pill; Drug: carvedilol; Drug: Methadone
Sponsors: Yale University; Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified December 2011 - Conditions: Bipolar Disorder; Bipolar Depression
Interventions: Drug: citalopram + mood stabilizer; Procedure: FDG PET scans; Procedure: MRI structural scans; Procedure: Genotyping; Procedure: Blood Draw; Drug: placebo + mood stabilizer
Sponsors: Tufts Medical Center; Tufts Medical Center; National Institute of Mental Health (NIMH)
Recruiting - verified July 2011 - Conditions: Postoperative Delirium; PD; Postoperative Cognitive Dysfunction; POCD
Interventions: Drug: Precedex (Dexmedetomidine); Drug: Placebo
Sponsors: Mount Sinai School of Medicine; Mount Sinai School of Medicine; National Institute on Aging (NIA)
Recruiting - verified January 2012 - Condition: Opiate Dependence
Interventions: Behavioral: Behavioral: Buprenorphine/naloxone maintenance (Mtn); Behavioral: Behavioral: Buprenorphine/naloxone detoxification (Dtx)
Sponsors: Yale University; Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified November 2011 - Condition: Metastatic Melanoma
Intervention: Drug: Proleukin and Dacarbazine
Sponsors: James Graham Brown Cancer Center; James Graham Brown Cancer Center
Recruiting - verified September 2011 - Condition: Prostate Cancer
Interventions: Radiation: 3-dimensional conformal radiation therapy; Radiation: intensity-modulated radiation therapy; Radiation: samarium Sm 153 lexidronam pentasodium
Sponsors: National Cancer Institute (NCI); Radiation Therapy Oncology Group; National Cancer Institute (NCI)
Recruiting - verified May 2012 - Condition: Breast Cancer
Intervention:
Sponsors: Beth Israel Deaconess Medical Center; Beth Israel Deaconess Medical Center
Recruiting - verified February 2012 - Conditions: Leukemia; Lymphoma
Intervention: Drug: T cell Induction via IL-2 to reduce GVHD
Sponsors: Baylor College of Medicine; Baylor College of Medicine; The Methodist Hospital System; Texas Children's Hospital; Center for Cell and Gene Therapy, Baylor College of Medicine
Recruiting - verified April 2012 - Condition: Lung Cancer
Interventions: Drug: celecoxib; Drug: Docetaxel; Drug: pemetrexed disodium; Other: laboratory biomarker analysis
Sponsors: Vanderbilt-Ingram Cancer Center; Vanderbilt-Ingram Cancer Center; National Cancer Institute (NCI)
Recruiting - verified October 2011 - Condition: Critically Ill Premature Neonates
Interventions: Drug: Morphine; Drug: Morphine
Sponsors: Children's Research Institute; Children's Research Institute; University of Louisville; State University of New York - Downstate Medical Center
Recruiting - verified April 2012 - Condition: Obstetric Labor, Premature
Intervention: Drug: Indomethacin and Nifedipine
Sponsors: Stanford University; Stanford University
Recruiting - verified June 2011 - Conditions: Psoriasis; Metabolic Syndrome; Hyperlipidemia; Obesity; Hypertension
Intervention: Drug: Etanercept
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; Amgen
Recruiting - verified February 2012 - Conditions: Hermansky-Pudlak Syndrome (HPS); Pulmonary Fibrosis; Oculocutaneous Albinism; Platelet Storage Pool Deficiency; Metabolic Disease
Interventions: Drug: Losartan; Drug: Zileuton; Drug: N-Acetylcysteine; Drug: Prevastatin; Drug: Erythromycin
Sponsors: National Institutes of Health Clinical Center (CC); National Human Genome Research Institute (NHGRI)
Recruiting - verified December 2010 - Condition: Multiple Sclerosis
Intervention: Drug: Aspirin
Sponsors: Mayo Clinic; Mayo Clinic; National Multiple Sclerosis Society
Recruiting - verified November 2011 - Conditions: Extubation; Respiration Disorders
Intervention: Drug: Dexmedetomidine
Sponsors: University of California, San Francisco; University of California, San Francisco
Recruiting - verified October 2011 - Condition: Chronic Lymphocytic Leukemia (CLL)
Intervention: Genetic: IL2
Sponsors: Baylor College of Medicine; Baylor College of Medicine; The Methodist Hospital System; Center for Cell and Gene Therapy, Baylor College of Medicine
Recruiting - verified August 2011 - Condition: Prostate Cancer
Interventions: Radiation: Samarium Sm 153 lexidronam pentasodium; Biological: Sargramostim; Biological: Recombinant vaccinia-TRICOM vaccine; Biological: Recombinant fowlpox-TRICOM vaccine
Sponsors: National Institutes of Health Clinical Center (CC); National Cancer Institute (NCI)
Recruiting - verified May 2012 - Condition: Epilepsies, Partial
Intervention: Drug: Pregabalin
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Condition: Epilepsies, Partial
Interventions: Drug: Placebo; Drug: Pregabalin
Sponsors: Pfizer; Pfizer
Recruiting - verified April 2012 - Conditions: Relapsed Acute Leukemia; Refractory Acute Leukemia
Intervention: Drug: Bortezomib with mitoxantrone, etoposide and cytarabine
Sponsors: Thomas Jefferson University; Thomas Jefferson University; Millennium Pharmaceuticals, Inc.
Recruiting - verified January 2012 - Conditions: Sleep Apnea, Obstructive; Respiration Disorders
Interventions: Procedure: supraglottoplasty with laser; Procedure: laser supraglottoplasty
Sponsors: Indiana University; Indiana University School of Medicine
Recruiting - verified March 2012 - Condition: Fibromyalgia
Intervention: Drug: Neurotropin
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Nursing Research (NINR)
Recruiting - verified October 2011 - Condition: Epilepsies, Partial
Interventions: Drug: Lyrica (pregabalin); Drug: placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified April 2012 - Conditions: Arthritis, Rheumatoid; Osteoarthritis
Interventions: Drug: celecoxib; Drug: Ibuprofen; Drug: Naproxen
Sponsors: Pfizer; Pfizer; The Cleveland Clinic
Recruiting - verified May 2012 - Conditions: Cocaine Abuse; Heroin Abuse
Interventions: Drug: Clonidine; Drug: Placebo
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified September 2011 - Condition: Precancerous Conditions
Intervention: Drug: Erlotinib & Celecoxib
Sponsors: Emory University; Emory University; National Institutes of Health (NIH)
Recruiting - verified January 2012 - Conditions: Leukoplakia, Oral; Benign Neoplasms
Interventions: Drug: sulindac; Drug: Placebo
Sponsors: Memorial Sloan-Kettering Cancer Center; Memorial Sloan-Kettering Cancer Center; Amrita Institute of Sciences, AIMS, Cochin, India; Weill Medical College of Cornell University; Regional Cancer Center(RCC), Trivandrum, India; Narayana Hrudayalaya Hospitals
Recruiting - verified January 2012 - Conditions: Cervical Cancer; Endometrial Cancer; Fallopian Tube Cancer; Ovarian Cancer; Pain; Perioperative/Postoperative Complications; Sarcoma
Interventions: Drug: fentanyl citrate; Drug: hydromorphone hydrochloride; Drug: ropivacaine hydrochloride
Sponsors: National Cancer Institute (NCI); University of California, San Francisco; National Cancer Institute (NCI)
Recruiting - verified September 2007 - Condition: Opioid-Related Disorders
Interventions: Drug: Clonidine; Drug: Placebo
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified March 2012 - Condition: Melanoma
Interventions: Biological: Dendritic Cell Immunization; Drug: Cyclophosphamide; Drug: Fludarabine; Biological: T Cells; Biological: Interleukin-2
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center; Chiron Corporation
Recruiting - verified March 2012 - Conditions: Tachycardia; Chronic Orthostatic Intolerance
Interventions: Drug: Acetazolamide; Drug: Atomoxetine; Other: Baseline (No Drug); Drug: Clonidine; Drug: Entacapone; Drug: Entacapone & Propranolol; Drug: Atomoxetine & Propranolol; Drug: Indomethacin; Drug: Mecamylamine; Drug: Isosorbide Dinitrate; Dietary Supplement: Melatonin; Drug: Midodrine; Drug: Modafinil; Drug: Octreotide; Radiation: Placebo; Drug: Propranolol; Drug: Modafinil & Propranolol; Drug: Sertraline; Procedure: IV Saline; Other: Drinking Water; Device: Breathing Device; Drug: memantine; Device: Abdominal binder
Sponsors: Vanderbilt University; Satish R. Raj; National Institutes of Health (NIH)
Recruiting - verified February 2012 - Condition: Rectal Cancer
Intervention: Drug: Oxaliplatin, Capecitabine, Celecoxib with Radiation
Sponsors: New Mexico Cancer Care Alliance; New Mexico Cancer Care Alliance
Recruiting - verified December 2011 - Condition: Functional Dyspepsia
Interventions: Drug: Amitriptyline; Drug: escitalopram; Drug: placebo
Sponsors: Mayo Clinic; Mayo Clinic; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified January 2012 - Condition: Coronary Arteriosclerosis
Interventions: Drug: HOE 140; Drug: Aminocaproic Acid; Drug: Placebo
Sponsors: Vanderbilt University; Vanderbilt University
Recruiting - verified July 2011 - Condition: Hypertension
Interventions: Drug: Clonidine; Drug: Nitroglycerin transdermal; Drug: Dipyridamole/ Aspirin (Aggrenox); Drug: Desmopressin (DDAVP); Drug: Sildenafil; Drug: Nifedipine; Drug: Hydralazine; Drug: Hydrochlorothiazide; Drug: Placebo; Drug: Bosentan; Drug: Diltiazem; Drug: Eplerenone; Drug: guanfacine; Dietary Supplement: L-arginine; Drug: captopril; Drug: carbidopa; Drug: losartan; Drug: metoprolol tartrate; Drug: nebivolol hydrochloride; Drug: prazosin hydrochloride; Drug: tamsulosin hydrochloride; Other: Head-up tilt.
Sponsors: Vanderbilt University; Vanderbilt University
Recruiting - verified May 2012 - Conditions: Autonomic Failure; Orthostatic Hypotension
Interventions: Drug: Atomoxetine; Drug: Acarbose; Drug: Pyridostigmine Bromide; Drug: Yohimbine; Drug: Midodrine HCl; Drug: placebo; Drug: Modafinil; Drug: Octreotide; Other: water intake; Drug: Diphenhydramine Hydrochloride; Drug: Ranitidine HCL; Drug: Tranylcypromine; Drug: Ergotamine/ Caffeine; Drug: Celecoxib; Drug: Pseudoephedrine; Drug: Methylphenidate; Drug: Indomethacin; Drug: Ibuprofen; Drug: Oxymetazoline 0.05% nasal solution; Dietary Supplement: Bovril; Drug: Acetazolamide; Drug: Rivastigmine tartrate; Drug: Carbidopa/levodopa; Device: abdominal binder; Device: abdominal binder (sham)
Sponsors: Vanderbilt University; Vanderbilt University
Recruiting - verified May 2012 - Condition: Pancreas Neoplasms
Intervention: Drug: celecoxib
Sponsors: Indiana University; Indiana University School of Medicine
Recruiting - verified March 2012 - Condition: Abruptio Placentae
Intervention: Drug: magnesium sulfate, Normal Saline
Sponsors: Stanford University; Stanford University
Recruiting - verified April 2012 - Conditions: Acute Lymphoblastic Leukemia; Lymphoma, Lymphoblastic
Interventions: Drug: Etoposide, cytarabine, vincristine, dexamethasone; Drug: methotrexate, teniposide, PEG-asparaginase; Drug: mitoxantrone, cyclophosphamide, mercaptopurine, vinblastine; Drug: L-asparaginase, erwinia asparaginase; Procedure: chemotherapy, intrathecal chemotherapy, steroid therapy; Procedure: Hematopoietic Stem Cell Transplant; Procedure: Natural Killer (NK) Cell Transplant
Sponsors: St. Jude Children's Research Hospital; St. Jude Children's Research Hospital
Recruiting - verified March 2012 - Condition: Lung Cancer
Intervention: Drug: celecoxib
Sponsors: University of California, Los Angeles; University of California, Los Angeles; Jonsson Comprehensive Cancer Center; National Cancer Institute (NCI)
Recruiting - verified February 2012 - Conditions: Depression; Major Depression/Bipolar Disorder
Interventions: Drug: Ketamine; Drug: Riluzole; Drug: FDG
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Mental Health (NIMH)
Recruiting - verified January 2012 - Condition: Cerebrovascular Accident
Interventions: Drug: Magnesium Sulfate; Drug: Normal Saline
Sponsors: University of California, Los Angeles; Jeffrey L. Saver; National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified December 2011 - Condition: Neuroblastoma
Interventions: Biological: aldesleukin; Biological: monoclonal antibody Ch14.18; Biological: sargramostim; Drug: isotretinoin
Sponsors: National Cancer Institute (NCI); Children's Oncology Group; National Cancer Institute (NCI)
Recruiting - verified May 2012 - Condition: Severe Combined Immunodeficiency Syndrome
Intervention: Drug: CD34+ cells transduced with ADA retrovir
Sponsors: National Institutes of Health Clinical Center (CC); National Human Genome Research Institute (NHGRI)
Recruiting - verified February 2012 - Conditions: CRPS-II (Causalgia); CRPS-I Reflex Sympathetic Dystrophy
Intervention: Drug: Neurotropin
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Nursing Research (NINR)
Recruiting - verified July 2011
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Analgesics Clinical Trials |
