- Conditions: Fabry Disease; Neuropathic Pain
Interventions: Drug: Gabapentin; Drug: placebo
Sponsors: University of Minnesota - Clinical and Translational Science Institute; University of Minnesota - Clinical and Translational Science Institute; Genzyme
Recruiting - verified April 2012 - Condition: Alcoholism
Interventions: Drug: Ondansetron + Brief Behavioral Enhancement Treatment; Drug: Placebo + Brief Behavioral Enhancement Treatment
Sponsors: University of Virginia; Bankole Johnson; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Not yet recruiting - verified May 2012 - Condition: AOD Effects and Consequences
Interventions: Drug: Alprazolam; Drug: Dextroamphetamine
Sponsors: Mclean Hospital; Mclean Hospital
Not yet recruiting - verified April 2012 - Condition: Healthy
Interventions: Drug: Ondansetron; Drug: Ondansetron + Hylenex; Drug: Zofran ODT; Drug: Ondansetron solution
Sponsors: Halozyme Therapeutics; Halozyme Therapeutics
Recruiting - verified April 2012 - Condition: Advanced Solid Tumors, Excluding Breast Cancer
Interventions: Drug: caffeine; Drug: diclofenac; Drug: omeprazole; Drug: midazolam; Drug: TKI258
Sponsors: Novartis; Novartis Pharmaceuticals
Not yet recruiting - verified May 2012 - Condition: Nausea and Vomiting
Interventions: Drug: lorazepam; Drug: diphenhydramine hydrochloride; Drug: haloperidol; Other: placebo
Sponsors: Virginia Commonwealth University; Virginia Commonwealth University; National Cancer Institute (NCI)
Recruiting - verified March 2012 - Condition: Degenerative Joint Disease of Hip and Knee.
Interventions: Drug: Placebo; Drug: Gapabentin
Sponsors: University of Medicine and Dentistry New Jersey; University of Medicine and Dentistry New Jersey
Recruiting - verified March 2012 - Condition: Healthy Volunteers
Interventions: Drug: Midazolam; Drug: vandetanib
Sponsors: AstraZeneca; AstraZeneca
Recruiting - verified April 2012 - Condition: Cancer of the Cervix
Interventions: Drug: Granisetron; Drug: Ondansetron; Behavioral: Questionnaires; Behavioral: Study Drug Diary
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center; Sancuso
Recruiting - verified March 2012 - Conditions: Opioid Withdrawal; Physical Dependence
Intervention: Drug: Ondansetron
Sponsors: Stanford University; Stanford University; National Institute on Drug Abuse (NIDA)
Recruiting - verified March 2012 - Condition: Hot Flashes in Men With Prostate Cancer Receiving Androgen Ablation Therapy
Interventions: Drug: Gabapentin; Drug: Venlafaxine
Sponsors: University of Wisconsin, Madison; University of Wisconsin, Madison
Recruiting - verified February 2012 - Conditions: Ultrasound; CT Scans; MRIs
Interventions: Drug: Dexmedetomidine; Drug: Midazolam; Drug: Fentanyl
Sponsors: Hospira, Inc.; Hospira, Inc.
Recruiting - verified April 2012 - Condition: Suicidal Ideation
Interventions: Drug: Ketamine; Drug: Midazolam
Sponsors: Mount Sinai School of Medicine; James Murrough
Recruiting - verified January 2012 - Condition: Anesthesia
Interventions: Drug: Midazolam; Drug: Fentanyl; Drug: Morphine
Sponsors: Hospira, Inc.; Hospira, Inc.
Recruiting - verified April 2012 - Condition: Solid Tumors
Interventions: Drug: tivantinib; Drug: omeprazole; Drug: s-warfarin; Drug: caffeine; Dietary Supplement: vitamin K; Drug: digoxin; Drug: midazolam
Sponsors: Daiichi Sankyo Inc.; Daiichi Sankyo Inc.; Medpace, Inc.
Recruiting - verified January 2012 - Condition: Postoperative Nausea and Vomiting
Interventions: Drug: Ondansetron; Drug: Vestipitant
Sponsors: Octagon Research Solutions, Inc.; Octagon Research Solutions, Inc.
Recruiting - verified May 2012 - Conditions: Acute Lymphoblastic Leukemia; Neuropathy; Neuropathic Pain
Interventions: Drug: gabapentin; Drug: placebo
Sponsors: St. Jude Children's Research Hospital; St. Jude Children's Research Hospital
Recruiting - verified January 2012 - Condition: Cocaine Dependence
Interventions: Drug: Ketamine; Drug: Lorazepam (control)
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2012 - Condition: Agitation
Interventions: Drug: Haloperidol; Drug: Midazolam
Sponsors: Catholic Health East; Catholic Health East
Recruiting - verified December 2011 - Conditions: Seizures; Epilepsy; Partial Epilepsy; Depression
Intervention: Drug: Buspirone
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified November 2011 - Conditions: Sciatica; Radiculopathy
Interventions: Procedure: epidural steroid injection; Procedure: Sham epidural steroid injection; Drug: Gabapentin; Drug: Placebo gabapentin
Sponsors: Johns Hopkins University; Johns Hopkins University; Walter Reed National Military Medical Center; Brooke Army Medical Center; Landstuhl Regional Medical Center; DC VA Hospital; San Diego Naval Hospital; Case Western Reserve University; Penn State-Hershey
Recruiting - verified March 2012 - Conditions: Colon Cancer; Rectal Cancer; Colonic Diverticulosis
Interventions: Drug: Fentanyl; Drug: Propofol; Drug: Midazolam
Sponsors: Saint Joseph Mercy Health System; Saint Joseph Mercy Health System
Recruiting - verified December 2011 - Conditions: PONV; Nausea
Interventions: Drug: Aprepitant; Drug: Ondansetron
Sponsors: Ohio State University; Sergio Bergese
Recruiting - verified November 2011 - Conditions: Nausea; Vomiting; Glioma
Interventions: Drug: Aprepitant and Ondansetron; Drug: Ondansetron
Sponsors: Duke University; Duke University; Merck
Not yet recruiting - verified March 2012 - Condition: Healthy Male Volunteer
Interventions: Drug: JNJ-38518168 (30 mg); Drug: JNJ-38518168 (10 mg); Drug: JNJ-38518168 (3 mg); Drug: Placebo; Drug: Midazolam and JNJ-38518168
Sponsors: Janssen Research & Development, LLC; Janssen Research & Development, LLC
Recruiting - verified April 2012 - Condition: Chemotherapy-Induced Nausea and Vomiting
Interventions: Drug: Palonosetron; Drug: Palonosetron; Drug: Ondansetron
Sponsors: Helsinn Healthcare SA; Helsinn Healthcare SA
Recruiting - verified May 2012 - Condition: Healthy Volunteer
Interventions: Drug: RO4917838; Drug: diazepam; Drug: Placebo
Sponsors: Hoffmann-La Roche; Hoffmann-La Roche
Recruiting - verified April 2012 - Conditions: Tourniquet-induced Pain; Tourniquet-induced Hypertension
Interventions: Drug: gabapentin 600 mg po; Drug: Placebo pill given one hour before surgery
Sponsors: Baylor College of Medicine; Baylor College of Medicine
Not yet recruiting - verified September 2011 - Condition: Bipolar Disorder I or II
Intervention: Drug: Tranylcypromine
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute
Recruiting - verified September 2011 - Condition: Insomnia
Intervention: Drug: Gabapentin
Sponsors: University at Buffalo; University at Buffalo
Recruiting - verified August 2011 - Condition: Epilepsy
Intervention: Drug: Diazepam
Sponsors: Neuronex, Inc.; Neuronex, Inc.
Recruiting - verified November 2011 - Condition: Postoperative Nausea and Vomiting
Interventions: Drug: Palonosetron; Drug: Ondansetron
Sponsors: Helsinn Healthcare SA; Helsinn Healthcare SA
Recruiting - verified January 2012 - Double-blind Trial of Buspirone for the Treatment of Anxiety in Youth With Autism Spectrum DisordersCondition: Autism Spectrum Disorder (ASD)
Interventions: Drug: Buspirone; Drug: Placebo
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified February 2012 - Conditions: Postoperative Nausea and Vomiting; Genetic Polymorphisms
Interventions: Drug: Ondansetron; Drug: Lorazepam; Drug: Aprepitant
Sponsors: University of California, San Francisco; University of California, San Francisco; National Cancer Institute (NCI)
Not yet recruiting - verified February 2012 - Condition: Chemotherapy-induced Nausea and Vomiting
Intervention: Drug: Palonosetron, ondansetron, dexamethasone
Sponsors: Northside Hospital, Inc.; Northside Hospital, Inc.; Blood and Marrow Transplant Group of Georgia
Recruiting - verified March 2012 - Condition: Obsessive Compulsive Disorder
Interventions: Drug: Ketamine; Drug: Midazolam
Sponsors: Goodman, Wayne, M.D.; Goodman, Wayne, M.D.
Not yet recruiting - verified June 2011 - Condition: Intubation; Difficult
Intervention: Drug: Midazolam
Sponsors: University of Vermont; University of Vermont
Recruiting - verified May 2011 - Conditions: Cannabis Dependence; Marijuana Dependence
Interventions: Drug: Nabilone; Drug: Placebo
Sponsors: Mclean Hospital; Mclean Hospital; National Institute on Drug Abuse (NIDA)
Recruiting - verified January 2012 - Condition: Anorexia Nervosa
Intervention:
Sponsors: National Institute of Mental Health (NIMH); National Institute of Mental Health (NIMH)
Recruiting - verified December 2010 - Conditions: Pain; Anxiety
Interventions: Device: Buzzy; Drug: Topical Lidocaine 4% Cream
Sponsors: Children's Hospital of Philadelphia; Children's Hospital of Philadelphia
Recruiting - verified May 2012 - Condition: Epilepsy
Intervention: Drug: intranasal midazolam hydrochloride
Sponsors: Columbia University; Columbia University
Recruiting - verified January 2012 - Condition: Obsessive-compulsive Disorder
Interventions: Drug: Ondansetron; Drug: Placebo
Sponsors: Transcept Pharmaceuticals; Transcept Pharmaceuticals
Recruiting - verified March 2012 - Condition: Cocaine Dependence
Intervention: Drug: Buspirone
Sponsors: The University of Texas Health Science Center, Houston; The University of Texas Health Science Center, Houston
Recruiting - verified March 2012 - Conditions: Alcohol Abuse; Alcohol Dependence
Interventions: Drug: ondansetron; Drug: placebo ondansetron; Drug: Ondansetron
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified February 2012 - Condition: Female Patients With High Tone Pelvic Floor Dysfunction
Interventions: Drug: Vaginal Diazepam Suppository; Drug: Placebo Suppository
Sponsors: TriHealth Inc.; TriHealth Inc.
Recruiting - verified September 2011 - Condition: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: dextromethorphan hydrobromide; Drug: gamma-secretase/Notch signalling pathway inhibitor RO4929097; Drug: ketoconazole; Drug: midazolam hydrochloride; Drug: omeprazole; Drug: rifampin; Drug: tolbutamide
Sponsors: National Cancer Institute (NCI); University of Wisconsin, Madison; National Cancer Institute (NCI)
Recruiting - verified July 2011 - Condition: Interstitial Cystitis
Interventions: Drug: Dexmedetomidine; Drug: Normal Saline
Sponsors: University of Rochester; University of Rochester
Recruiting - verified August 2011 - Condition: Cervical Radiculopathy
Interventions: Other: Gabapentin and/or Nortriptyline, Physical therapy; Procedure: Epidural Steroid Injections (ESI); Other: Combination treatment
Sponsors: Johns Hopkins University; Johns Hopkins University; Walter Reed Army Medical Center
Recruiting - verified September 2010 - Condition: Vulvodynia
Intervention: Drug: Gabapentin
Sponsors: University of Tennessee; University of Tennessee; University of Tennessee Health Science Center
Not yet recruiting - verified November 2011 - Condition: Phobic Disorders
Interventions: Behavioral: Individual Cognitive Behavioral Therapy (CBT); Drug: D-Cycloserine; Drug: Placebo
Sponsors: Southern Methodist University; Southern Methodist University
Recruiting - verified July 2011 - Conditions: Post Operative Nausea and Vomiting; Rescue Emetic Therapy
Interventions: Drug: Metaclopramide; Drug: Ondansetron; Drug: diphenhydramine; Drug: Saline
Sponsors: Children's Hospital of Pittsburgh; Children's Hospital of Pittsburgh
Recruiting - verified September 2009 - Conditions: Pain; Breast Cancer; Lung Cancer
Interventions: Drug: Gabapentin; Drug: Placebo
Sponsors: Stanford University; Stanford University
Recruiting - verified September 2011 - Condition: Major Depressive Disorder
Intervention: Drug: tranylcypromine
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute of Mental Health (NIMH)
Recruiting - verified December 2011 - Condition: Hot Flashes
Intervention: Drug: Gabapentin
Sponsors: Abramson Cancer Center of the University of Pennsylvania; Abramson Cancer Center of the University of Pennsylvania
Recruiting - verified May 2012 - Condition: Hepatitis C
Interventions: Drug: Midazolam; Drug: BMS-791325
Sponsors: Bristol-Myers Squibb; Bristol-Myers Squibb
Not yet recruiting - verified February 2012 - Conditions: Cannabis Dependence; Cannabis Withdrawal; Cognitive Deficits
Interventions: Drug: gabapentin 1200mg/day; Drug: Placebo
Sponsors: The Scripps Research Institute; The Scripps Research Institute
Recruiting - verified March 2012 - Conditions: Nausea; Vomiting
Interventions: Drug: aprepitant; Drug: Ondansetron
Sponsors: University of Vermont; University of Vermont; Mayo Clinic; Comprehensive Cancer Center of Wake Forest University
Recruiting - verified March 2012 - Conditions: Hematologic Diseases; Acute Myelogenous Leukemia; Myelodysplastic Syndrome; Chronic Myelogenous Leukemia
Interventions: Drug: Ondansetron; Drug: Aprepitant
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center
Recruiting - verified January 2012 - Condition: Postoperative Pain
Interventions: Drug: Gabapentin; Drug: pregabalin
Sponsors: Loma Linda University; Loma Linda University
Recruiting - verified March 2012 - Condition: Marijuana Abuse
Intervention: Drug: bupropion, diazepam, dronabinol, ramelteon (Investigational Drug)
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute on Drug Abuse (NIDA)
Recruiting - verified May 2009 - Conditions: Alcohol Abuse; Alcoholism
Interventions: Drug: Ondansetron + BASICS Plus; Drug: Placebo + BASICS Plus
Sponsors: University of Virginia; Bankole Johnson; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified February 2012 - Condition: Marijuana Dependence
Interventions: Drug: Buspirone; Drug: Placebo
Sponsors: Medical University of South Carolina; Medical University of South Carolina; National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2012 - Condition: Autistic Disorder
Interventions: Drug: Buspirone; Drug: Buspirone; Drug: Placebo
Sponsors: Chugani, Diane C.; Chugani, Diane C.
Recruiting - verified July 2011 - Condition: Bruxism
Intervention: Drug: Botulinum toxin type A
Sponsors: Baylor College of Medicine; Baylor College of Medicine; Allergan
Recruiting - verified September 2010 - Condition: Postoperative Nausea and Vomiting
Interventions: Drug: aprepitant; Drug: Comparator: Ondansetron
Sponsors: Merck; Merck
Recruiting - verified May 2012 - Condition: Chemotherapy-Induced Nausea and Vomiting
Interventions: Drug: Experimental: aprepitant; Drug: Experimental: aprepitant; Drug: Experimental: aprepitant; Drug: Experimental: aprepitant; Drug: Experimental: aprepitant; Drug: Experimental: aprepitant; Drug: Experimental: fosaprepitant; Drug: Experimental: fosaprepitant; Drug: Experimental: fosaprepitant; Drug: Comparator: ondansetron
Sponsors: Merck; Merck
Recruiting - verified May 2012 - Condition: Postpartum Depression
Intervention: Drug: Escitalopram
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; Forest Laboratories
Recruiting - verified July 2011 - Conditions: Stress Disorders, Post-Traumatic; PTSD; Depression; Anxiety Disorder
Interventions: Drug: Midazolam; Drug: Ketamine
Sponsors: Mount Sinai School of Medicine; Dennis Charney; Department of Defense
Recruiting - verified March 2012 - Conditions: Alcohol Dependence; Anxiety Disorder
Intervention: Drug: disulfiram plus lorazepam
Sponsors: University of New Mexico; University of New Mexico; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified January 2012 - Condition: Cocaine Dependence
Interventions: Drug: Ondansetron; Drug: Placebo
Sponsors: University of Virginia; University of Virginia; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Conditions: Breast Cancer; Depression; Hot Flashes; Psychosocial Effects of Cancer and Its Treatment
Interventions: Drug: citalopram hydrobromide; Drug: escitalopram oxalate; Drug: gabapentin; Drug: sertraline hydrochloride; Drug: tamoxifen citrate; Drug: venlafaxine; Genetic: molecular genetic technique; Other: high performance liquid chromatography; Other: laboratory biomarker analysis; Other: pharmacological study; Procedure: adjuvant therapy
Sponsors: Mayo Clinic; Mayo Clinic; National Cancer Institute (NCI)
Recruiting - verified April 2012 - Condition: Status Epilepticus
Intervention: Drug: lorazepam or diazepam
Sponsors: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - verified February 2012 - Conditions: Diabetic Neuropathic Pain; Chronic Low Back Pain
Interventions: Drug: donepezil; Drug: duloxetine; Drug: donepezil 2.5 mg and duloxetine 30mg; Drug: placebo; Drug: gabapentin
Sponsors: Wake Forest University; Wake Forest University; National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified February 2012 - Conditions: Minor Surgical Procedures With Monitored Anesthesia Care.; Driving Performance After Minor Ambulatory Surgery.
Interventions: Other: Control; Drug: Midazolam; Drug: Sufentanil; Drug: Propofol
Sponsors: Rush University Medical Center; Rush University Medical Center
Recruiting - verified April 2012 - Condition: Type 1 Diabetes
Interventions: Drug: Alprazolam; Drug: Placebo
Sponsors: University of Maryland; University of Maryland; National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified July 2011 - Conditions: Autonomic Failure; Orthostatic Hypotension
Interventions: Drug: Atomoxetine; Drug: Acarbose; Drug: Pyridostigmine Bromide; Drug: Yohimbine; Drug: Midodrine HCl; Drug: placebo; Drug: Modafinil; Drug: Octreotide; Other: water intake; Drug: Diphenhydramine Hydrochloride; Drug: Ranitidine HCL; Drug: Tranylcypromine; Drug: Ergotamine/ Caffeine; Drug: Celecoxib; Drug: Pseudoephedrine; Drug: Methylphenidate; Drug: Indomethacin; Drug: Ibuprofen; Drug: Oxymetazoline 0.05% nasal solution; Dietary Supplement: Bovril; Drug: Acetazolamide; Drug: Rivastigmine tartrate; Drug: Carbidopa/levodopa; Device: abdominal binder; Device: abdominal binder (sham)
Sponsors: Vanderbilt University; Vanderbilt University
Recruiting - verified May 2012 - Condition: Alcoholism
Interventions: Drug: ondansetron + cognitive behavioral therapy; Drug: topiramate + cognitive behavioral therapy; Drug: Placebo + cognitive behavioral therapy; Drug: ondansetron + topiramate + cognitive behavioral therapy
Sponsors: University of Virginia; Bankole Johnson; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified February 2012
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Anti Anxiety Agents Clinical Trials |
