- Condition: Spinal Cord Injury
Interventions: Drug: Riluzole; Drug: Placebo; Other: No intervention
Sponsors: SpineNet; SpineNet
Not yet recruiting - verified May 2012 - Conditions: Atrial Fibrillation; Electrical Cardioversion
Interventions: Drug: Magnesium Sulfate; Other: Placebo
Sponsors: State University of New York at Buffalo; State University of New York at Buffalo
Recruiting - verified May 2012 - Condition: Treatment-Resistant Depression
Intervention:
Sponsors: Mclean Hospital; Mclean Hospital; Pfizer; Massachusetts General Hospital
Not yet recruiting - verified May 2012 - Condition: Depression
Intervention: Dietary Supplement: Magnesium sulfate
Sponsors: University of Miami; University of Miami; Life Extension Foundation
Recruiting - verified May 2012 - Conditions: Fabry Disease; Neuropathic Pain
Interventions: Drug: Gabapentin; Drug: placebo
Sponsors: University of Minnesota - Clinical and Translational Science Institute; University of Minnesota - Clinical and Translational Science Institute; Genzyme
Recruiting - verified April 2012 - Condition: Tourette's Disorder
Intervention: Drug: vigabatrin
Sponsors: New York University School of Medicine; New York University School of Medicine
Not yet recruiting - verified April 2012 - Condition: Nausea and Vomiting
Interventions: Drug: lorazepam; Drug: diphenhydramine hydrochloride; Drug: haloperidol; Other: placebo
Sponsors: Virginia Commonwealth University; Virginia Commonwealth University; National Cancer Institute (NCI)
Recruiting - verified March 2012 - Condition: Advanced Cancers
Interventions: Drug: Temsirolimus; Drug: Bevacizumab; Drug: Valproic Acid; Drug: Cetuximab
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center
Recruiting - verified March 2012 - Condition: Degenerative Joint Disease of Hip and Knee.
Interventions: Drug: Placebo; Drug: Gapabentin
Sponsors: University of Medicine and Dentistry New Jersey; University of Medicine and Dentistry New Jersey
Recruiting - verified March 2012 - Conditions: Bipolar I Disorder; Bipolar II Disorder
Interventions: Drug: Lithium/Lithium Carbonate; Drug: Divalproex; Drug: Lamotrigine; Drug: Quetiapine
Sponsors: The University of Texas Health Science Center at San Antonio; The University of Texas Health Science Center at San Antonio; National Institute of Mental Health (NIMH)
Recruiting - verified May 2012 - Condition: Pulmonary Disease, Chronic Obstructive
Interventions: Drug: PH-797804; Drug: PH-797804; Drug: PH-797804; Drug: PH-797804; Drug: PH-797804; Drug: Placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Conditions: Alzheimer's Disease; Seizures
Intervention: Drug: Low/High/Placebo Dose Keppra (Levetiracetam)
Sponsors: Beth Israel Deaconess Medical Center; Beth Israel Deaconess Medical Center
Recruiting - verified March 2012 - Condition: Hot Flashes in Men With Prostate Cancer Receiving Androgen Ablation Therapy
Interventions: Drug: Gabapentin; Drug: Venlafaxine
Sponsors: University of Wisconsin, Madison; University of Wisconsin, Madison
Recruiting - verified February 2012 - Condition: Healthy
Interventions: Drug: Lacosamide (LCM); Drug: Carbamazepine Immediate Release (CBZ-IR)
Sponsors: UCB, Inc.; UCB, Inc.
Recruiting - verified May 2012 - Condition: Benign Childhood Epilepsy With Centro-Temporal Spikes
Intervention: Drug: Levetiracetam
Sponsors: Children's Hospital Medical Center, Cincinnati; Children's Hospital Medical Center, Cincinnati; National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified January 2012 - Condition: Asthma
Interventions: Drug: Magnesium Sulfate; Drug: Placebo
Sponsors: University of Louisville; University of Louisville
Recruiting - verified January 2012 - Condition: Asthma
Intervention: Drug: Nebulized magnesium sulfate
Sponsors: University of Texas Southwestern Medical Center; University of Texas Southwestern Medical Center
Recruiting - verified September 2011 - Condition: Cannabis-use Disorders
Intervention: Drug: Tiagabine
Sponsors: University of Kentucky; University of Kentucky
Recruiting - verified January 2012 - Conditions: Acute Lymphoblastic Leukemia; Neuropathy; Neuropathic Pain
Interventions: Drug: gabapentin; Drug: placebo
Sponsors: St. Jude Children's Research Hospital; St. Jude Children's Research Hospital
Recruiting - verified January 2012 - Condition: Cocaine Dependence
Interventions: Drug: Ketamine; Drug: Lorazepam (control)
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2012 - Condition: Acute Stroke
Intervention: Drug: Magnesium Sulfate
Sponsors: University of Southern California; University of Southern California; University of California, Los Angeles
Not yet recruiting - verified December 2011 - Conditions: Alcohol Use Disorders; Bipolar Disorder
Interventions: Drug: Zonisamide; Drug: Placebo
Sponsors: VA Connecticut Healthcare System; VA Connecticut Healthcare System; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Not yet recruiting - verified May 2012 - Condition: Diabetic Peripheral Neuropathy
Interventions: Drug: DS-5565 tablet; Drug: pregabalin capsule; Drug: Placebo
Sponsors: Daiichi Sankyo Inc.; Daiichi Sankyo Inc.
Recruiting - verified March 2012 - Conditions: Migraine; Migraine Disorders; Headache
Interventions: Drug: Amitriptyline; Drug: Topiramate; Drug: Placebo
Sponsors: Children's Hospital Medical Center, Cincinnati; Children's Hospital Medical Center, Cincinnati; National Institute of Neurological Disorders and Stroke (NINDS)
Not yet recruiting - verified April 2012 - Conditions: Sciatica; Radiculopathy
Interventions: Procedure: epidural steroid injection; Procedure: Sham epidural steroid injection; Drug: Gabapentin; Drug: Placebo gabapentin
Sponsors: Johns Hopkins University; Johns Hopkins University; Walter Reed National Military Medical Center; Brooke Army Medical Center; Landstuhl Regional Medical Center; DC VA Hospital; San Diego Naval Hospital; Case Western Reserve University; Penn State-Hershey
Recruiting - verified March 2012 - Condition: Epilepsy
Intervention: Drug: Lacosamide
Sponsors: UCB, Inc.; UCB, Inc.
Recruiting - verified May 2012 - Condition: Epilepsy
Intervention: Drug: ezogabine/retigabine
Sponsors: GlaxoSmithKline; GlaxoSmithKline; Valeant Pharmaceuticals International, Inc.
Not yet recruiting - verified April 2012 - Condition: Epilepsy
Intervention:
Sponsors: Cyberonics, Inc.; Cyberonics, Inc.
Recruiting - verified November 2011 - Condition: Neonatal Seizures
Intervention:
Sponsors: Children's Hospital Medical Center, Cincinnati; Stephanie Merhar, MD
Recruiting - verified November 2011 - Condition: Central Nervous System
Intervention: Drug: perampanel
Sponsors: Eisai Inc.; Eisai Inc.
Recruiting - verified January 2012 - Condition: Diabetic Peripheral Neuropathy
Interventions: Drug: Pregabalin; Other: placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Conditions: Acute Myelogenous Leukemia; Refractory Acute Myelogenous Leukemia
Interventions: Drug: Allopurinol; Drug: Fludarabine; Radiation: Total body irradiation; Drug: Cyclophosphamide; Drug: Levetiracetam; Drug: Busulfan; Biological: Umbilical Cord Blood Transplantation; Biological: Interleukin-2
Sponsors: Masonic Cancer Center, University of Minnesota; Masonic Cancer Center, University of Minnesota
Recruiting - verified November 2011 - Condition: Epilepsy
Intervention: Drug: Retigabine / Ezogabine
Sponsors: GlaxoSmithKline; GlaxoSmithKline
Recruiting - verified January 2012 - Condition: Painful Diabetic Peripheral Neuropathy
Interventions: Drug: pregabalin; Drug: placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Conditions: Epilepsy, Partial Seizures; Epilepsy, Primary Generalized Tonic-Clonic Seizures
Intervention: Drug: Pregabalin
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Conditions: Uterine Fibroids; Uterine Artery Embolization
Interventions: Drug: pregabalin/celecoxib; Drug: pregabalin/placebo; Drug: celecoxib/placebo; Drug: Placebo group
Sponsors: Northwestern University; Northwestern University
Recruiting - verified March 2012 - Conditions: Anesthesia; Neuromuscular Blockade
Interventions: Drug: Remifentanil infusion; Drug: Rocuronium dose + Remifentanil infusion; Drug: Rocuronium dose + Remifentanil infusion; Drug: Rocuronium dose + Remifentanil infusion; Drug: Remifentanil infusion; Drug: Rocuronium dose + Remifentanil infusion; Drug: Rocuronium dose + Remifentanil infusion; Drug: Rocuronium dose + Remifentanil infusion
Sponsors: Covidien; Covidien
Recruiting - verified May 2012 - Conditions: Tourniquet-induced Pain; Tourniquet-induced Hypertension
Interventions: Drug: gabapentin 600 mg po; Drug: Placebo pill given one hour before surgery
Sponsors: Baylor College of Medicine; Baylor College of Medicine
Not yet recruiting - verified September 2011 - Condition: Healthy Volunteer
Interventions: Drug: RO4917838; Drug: diazepam; Drug: Placebo
Sponsors: Hoffmann-La Roche; Hoffmann-La Roche
Recruiting - verified April 2012 - Condition: Chronic Obstructive Pulmonary Disease
Interventions: Drug: Aclidinium Bromide/Formoterol Fumarate; Drug: Aclidinium Bromide/Formoterol Fumarate; Drug: Aclidinium Bromide; Drug: Formoterol Fumarate; Drug: placebo
Sponsors: Forest Laboratories; Forest Laboratories; Almirall, S.A.
Recruiting - verified March 2012 - Condition: Neoplasms
Interventions: Drug: Gemcitabine; Drug: BAY80-6946; Drug: Cisplatin; Drug: NaCl; Drug: BAY80-6964 fixed dose
Sponsors: Bayer; Bayer
Recruiting - verified May 2012 - Condition: Glioblastoma Multiforme
Intervention: Drug: Temozolomide, bevacizumab and bortezomib
Sponsors: Emory University; Emory University
Recruiting - verified March 2012 - Conditions: Pain; Opioid Use, Unspecified, Uncomplicated
Interventions: Drug: Placebo infusion of .9 normal saline; Drug: administration of magnesium sulfate
Sponsors: Northwestern University; Northwestern University
Recruiting - verified February 2012 - Condition: Fibromyalgia
Interventions: Drug: Pregabalin; Drug: placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Condition: Primary Hypomagnesemia (Disorder)
Intervention: Drug: Magnesium Sulfate
Sponsors: CAMC Health System; CAMC Health System; Sara and Pauline Maier Foundation, Inc.
Recruiting - verified December 2011 - Condition: Insomnia
Intervention: Drug: Gabapentin
Sponsors: University at Buffalo; University at Buffalo
Recruiting - verified August 2011 - Condition: Epilepsy
Intervention: Drug: Diazepam
Sponsors: Neuronex, Inc.; Neuronex, Inc.
Recruiting - verified November 2011 - Condition: Heart Failure
Intervention: Drug: Pyridostigmine Bromide
Sponsors: New York University School of Medicine; New York University School of Medicine; Nathan Kline Institute for Psychiatric Research; Oklahoma State University Center for Health Sciences; National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting - verified August 2011 - Condition: Cyanotic Congenital Heart Disease
Interventions: Drug: Topiramate; Other: No medication, but routine heart surgery
Sponsors: University of California, Davis; University of California, Davis
Recruiting - verified August 2011 - Condition: Epilepsy
Intervention: Drug: Brivaracetam
Sponsors: UCB, Inc.; UCB, Inc.
Recruiting - verified May 2012 - Condition: Lennox-Gastaut Syndrome
Interventions: Drug: Rufinamide; Drug: Any other approved AED
Sponsors: Eisai Inc.; Eisai Inc.
Recruiting - verified April 2012 - Conditions: Alcohol Dependence; Alcoholism; Alcohol Abuse; Alcohol Use Disorder; PTSD; Posttraumatic Stress Disorder
Interventions: Drug: Topiramate; Drug: Placebo
Sponsors: University of Maryland; University of Maryland; Department of Veterans Affairs
Not yet recruiting - verified August 2011 - Condition: Fibromyalgia
Intervention: Drug: Pregabalin
Sponsors: Newton-Wellesley Hospital; Newton-Wellesley Hospital; Pfizer
Not yet recruiting - verified July 2011 - Conditions: Postoperative Nausea and Vomiting; Genetic Polymorphisms
Interventions: Drug: Ondansetron; Drug: Lorazepam; Drug: Aprepitant
Sponsors: University of California, San Francisco; University of California, San Francisco; National Cancer Institute (NCI)
Not yet recruiting - verified February 2012 - Condition: Epilepsy, Partial Seizures
Interventions: Drug: Pregabalin add-on therapy; Drug: Pregabalin add-on therapy; Drug: Pregabalin add-on therapy
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Condition: Heart Failure
Interventions: Drug: Acetazolamide; Drug: Placebo
Sponsors: Brigham and Women's Hospital; Atul Malhotra, MD; American Heart Association
Recruiting - verified August 2011 - Conditions: Alpha-1-antitrypsin Deficiency; Liver Cirrhosis
Interventions: Drug: Drug-Carbamazepine (Tegretol XR); Drug: Carbamazepine (Tegretol XR) Placebo
Sponsors: University of Pittsburgh; University of Pittsburgh; Novartis; National Institutes of Health (NIH); National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Not yet recruiting - verified January 2012 - Condition: Lumbar Spinal Fusions
Interventions: Drug: Pregabalin 150 mg; Drug: Placebo
Sponsors: Hospital for Special Surgery, New York; Hospital for Special Surgery, New York; Pfizer
Recruiting - verified June 2011 - Conditions: Orthostatic Hypotension; Multiple System Atrophy
Interventions: Drug: Droxidopa; Drug: Pyridostigmine Bromide
Sponsors: Mayo Clinic; Mayo Clinic
Recruiting - verified December 2011 - Condition: Bipolar Disorder
Intervention: Drug: Lithium, valproate, lamotrigine
Sponsors: Emory University; Emory University
Recruiting - verified October 2011 - Conditions: Obesity; Metabolic Syndrome X
Interventions: Drug: Metformin; Drug: Orlistat; Drug: Topiramate; Drug: Placebo
Sponsors: University of Iowa; University of Iowa
Recruiting - verified April 2012 - Condition: Alcohol Dependence
Interventions: Drug: Valproate; Drug: Naltrexone
Sponsors: Department of Veterans Affairs; Department of Veterans Affairs
Recruiting - verified March 2012 - Condition: Partial Onset Seizures
Intervention: Drug: BGG492
Sponsors: Novartis; Novartis Pharmaceuticals
Recruiting - verified December 2011 - Conditions: Alcoholism; Cocaine Dependence
Interventions: Drug: Vigabatrin; Drug: Placebo
Sponsors: University of Pennsylvania; University of Pennsylvania
Recruiting - verified August 2011 - Condition: Traumatic Brain Injury
Interventions: Device: Arctic Sun; Drug: Magnesium Sulfate
Sponsors: Department of Defense; Department of Defense
Recruiting - verified December 2011 - Condition: Primary Total Knee Arthroplasty
Interventions: Drug: Pregabalin 50mg; Drug: Pregabalin 100mg; Drug: Pregabalin 150mg; Drug: Placebo
Sponsors: Hospital for Special Surgery, New York; Hospital for Special Surgery, New York
Recruiting - verified December 2011 - Conditions: Epilepsy; Anxiety
Interventions: Drug: Pregabalin-Lyrica; Drug: Sertraline
Sponsors: Rush University Medical Center; Rush University Medical Center
Recruiting - verified September 2011 - Conditions: Depression; Unipolar Depression; Treatment Resistant Depression
Intervention: Behavioral: Medication
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Mental Health (NIMH)
Not yet recruiting - verified November 2011 - Condition: Diabetic Peripheral Neuropathic Pain
Interventions: Drug: BMS-954561; Drug: Pregabalin; Drug: BMS-954561; Drug: Placebo matching BMS-954561; Drug: Placebo matching Pregabalin
Sponsors: Bristol-Myers Squibb; Bristol-Myers Squibb
Recruiting - verified March 2011 - Conditions: Fibromyalgia; Painful Diabetic Peripheral Neuropathy
Interventions: Other: prior authorization; Other: no prior authorization; Other: prior authorization; Other: no prior authorization
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Condition: Adult Refractory Complex Partial Seizures
Intervention: Drug: Vigabatrin
Sponsors: Lundbeck LLC; Lundbeck LLC
Recruiting - verified January 2012 - Condition: Bipolar Affective Disorder
Intervention: Drug: Mood stabilizer treatment
Sponsors: University of California, San Diego; University of California, San Diego
Recruiting - verified April 2012 - Condition: Fibromyalgia
Interventions: Drug: pregabalin; Drug: placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Condition: Post Herpetic Neuralgia
Interventions: Drug: Pregabalin; Drug: placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Condition: Complex Partial Seizures
Intervention: Drug: vigabatrin
Sponsors: University of Pennsylvania; University of Pennsylvania
Recruiting - verified November 2011 - Condition: Acute Migraine
Interventions: Drug: Metoclorpamide; Drug: Ketorolac; Drug: Valproate
Sponsors: Montefiore Medical Center; Montefiore Medical Center
Recruiting - verified April 2012 - Condition: Congenital Pediatric Disorders
Interventions: Drug: Busulfan; Drug: Cyclophosphamide; Drug: Fludarabine
Sponsors: Baylor College of Medicine; Baylor College of Medicine; Texas Children's Hospital
Recruiting - verified August 2011 - Condition: Female Patients With High Tone Pelvic Floor Dysfunction
Interventions: Drug: Vaginal Diazepam Suppository; Drug: Placebo Suppository
Sponsors: TriHealth Inc.; TriHealth Inc.
Recruiting - verified September 2011 - Condition: Retinitis Pigmentosa
Interventions: Drug: Valproic Acid; Drug: Placebo
Sponsors: National Neurovision Research Institute; National Neurovision Research Institute; Department of Defense
Recruiting - verified April 2012 - Condition: Cervical Spondylotic Myelopathy
Interventions: Drug: riluzole; Drug: Placebo medication
Sponsors: SpineNet; SpineNet
Recruiting - verified April 2012 - Condition: Depression
Interventions: Drug: Riluzole; Drug: placebo
Sponsors: Yale University; Yale University
Recruiting - verified March 2012 - Condition: Thyroid Neoplasm
Intervention: Drug: Valproic Acid
Sponsors: National Institutes of Health Clinical Center (CC); National Cancer Institute (NCI)
Recruiting - verified September 2011 - Conditions: Diffuse, Large B-Cell, Lymphoma; Lymphoma, Low-Grade; T-Cell Lymphoma; Mantle-Cell Lymphoma; Hodgkin's Lymphoma; Chronic Lymphocytic Leukemia; Lymphoma, Small Lymphocytic
Interventions: Drug: Busulfan; Drug: Etoposide; Drug: Cyclophosphamide; Drug: Mesna; Drug: Phenytoin; Drug: Ursodiol; Other: Infusion of autologous peripheral blood stem cells; Drug: Neupogen; Drug: Fludarabine; Drug: Busulfan; Other: Peripheral blood stem cell transplant; Drug: Tacrolimus; Drug: Sirolimus; Drug: Methotrexate
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; Dana-Farber Cancer Institute
Recruiting - verified April 2012 - Conditions: Alcohol Dependence; Nicotine Dependence
Interventions: Drug: Topiramate with brief behavioral enhancement therapy; Drug: Placebo plus brief behavioral enhancement therapy
Sponsors: University of Virginia; University of Virginia; National Institute on Alcohol Abuse and Alcoholism (NIAAA); M.D. Anderson Cancer Center; University of California, San Diego
Recruiting - verified March 2012 - Condition: Neonatal Abstinence Syndrome
Interventions: Drug: Clonidine; Drug: Phenobarbital
Sponsors: Baystate Medical Center; Baystate Medical Center
Recruiting - verified April 2012 - Condition: Cervical Radiculopathy
Interventions: Other: Gabapentin and/or Nortriptyline, Physical therapy; Procedure: Epidural Steroid Injections (ESI); Other: Combination treatment
Sponsors: Johns Hopkins University; Johns Hopkins University; Walter Reed Army Medical Center
Recruiting - verified September 2010 - Condition: Memory Impairment
Interventions: Drug: Lamotrigine; Drug: Placebo
Sponsors: University of Texas Southwestern Medical Center; University of Texas Southwestern Medical Center; National Institute of Mental Health (NIMH)
Recruiting - verified August 2011 - Condition: Cocaine Dependence
Interventions: Drug: Zonisamide; Drug: Placebo; Drug: Cocaine Hydrochloride; Behavioral: Neurocognitive and Performance Battery; Behavioral: Smoking Assessments
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute on Drug Abuse (NIDA)
Recruiting - verified June 2011 - Conditions: HIV-1 Infection; Neuropathic Pain
Intervention: Drug: pregabalin (Lyrica)
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Condition: Subarachnoid Hemorrhage
Interventions: Drug: Levetiracetam short course; Drug: Levetiracetam Long course
Sponsors: Washington University School of Medicine; Washington University School of Medicine
Recruiting - verified March 2012 - Condition: Epilepsy
Intervention: Drug: Intravenous Carbamazepine (IV CBZ)
Sponsors: Lundbeck LLC; Lundbeck LLC; CyDex Pharmaceuticals, Inc.; ICON Clinical Research; Quintiles
Recruiting - verified April 2012 - Condition: Refractory Partial Epilepsy
Interventions: Drug: Pregabalin; Drug: Pregabalin
Sponsors: Northeast Regional Epilepsy Group; Northeast Regional Epilepsy Group; Pfizer
Recruiting - verified July 2011 - Condition: Vulvodynia
Intervention: Drug: Gabapentin
Sponsors: University of Tennessee; University of Tennessee; University of Tennessee Health Science Center
Not yet recruiting - verified November 2011 - Condition: Headache, Migraine
Interventions: Drug: ethosuximide; Other: placebo comparator
Sponsors: Department of Veterans Affairs; Department of Veterans Affairs; Thomas Jefferson University; University of Pittsburgh
Recruiting - verified January 2012 - Condition: Seizure Disorders
Intervention: Drug: Dexmedetomidine
Sponsors: University of California, San Francisco; University of California, San Francisco
Recruiting - verified June 2011 - Conditions: Brain Cancer; Glioblastoma Multiforme
Interventions: Drug: Vorinostat; Drug: Erlotinib; Drug: Temozolomide
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center; Merck
Recruiting - verified February 2012 - Conditions: Cannabis Abuse; Cannabis Dependence
Interventions: Drug: Topiramate; Drug: Placebo
Sponsors: Brown University; Brown University; National Institute on Drug Abuse (NIDA)
Recruiting - verified July 2011 - Conditions: Chemotherapeutic Agent Toxicity; Colorectal Cancer; Neuropathy; Neurotoxicity
Interventions: Drug: calcium gluconate; Drug: magnesium sulfate; Other: placebo
Sponsors: National Cancer Institute (NCI); North Central Cancer Treatment Group; National Cancer Institute (NCI)
Recruiting - verified May 2012 - Condition: Epilepsy
Interventions: Drug: Eslicarbazepine acetate 1600 mg; Drug: Eslicarbazepine acetate 1200 mg
Sponsors: Sunovion; Sunovion
Recruiting - verified February 2012 - Conditions: Sarcoma; Soft Tissue Sarcoma; Locally Advanced Sarcoma; Unresectable Sarcoma; Metastatic Sarcoma
Intervention: Drug: Bevacizumab, Gemcitabine, docetaxel and valproic acid
Sponsors: University of Iowa; University of Iowa; Genentech
Recruiting - verified June 2011 - Condition: Drug Dependence
Intervention: Drug: 2-4 of the drugs listed below
Sponsors: University of Arkansas; University of Arkansas; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Conditions: Pain; Breast Cancer; Lung Cancer
Interventions: Drug: Gabapentin; Drug: Placebo
Sponsors: Stanford University; Stanford University
Recruiting - verified September 2011 - Condition: Mild Cognitive Impairment (MCI)
Interventions: Drug: Levetiracetam; Drug: Placebo; Drug: Placebo
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute on Aging (NIA)
Recruiting - verified March 2012 - Condition: Bipolar Depression
Intervention: Drug: Lamotrigine 12 week open trial
Sponsors: Mayo Clinic; Mayo Clinic; National Institute of Mental Health (NIMH)
Recruiting - verified April 2012 - Conditions: Metastatic Cancer; Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: riluzole; Radiation: whole-brain radiation therapy
Sponsors: University of Medicine and Dentistry New Jersey; University of Medicine and Dentistry New Jersey; National Cancer Institute (NCI)
Recruiting - verified December 2011 - Conditions: Childhood Obsessive-Compulsive Disorder; Autism Spectrum Disorders
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Mental Health (NIMH)
Recruiting - verified September 2011 - Condition: Fibromyalgia
Intervention: Drug: pregabalin
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Condition: Fibromyalgia
Interventions: Drug: placebo; Drug: pregabalin (Lyrica)
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Condition: Tourette Syndrome
Interventions: Drug: D-serine; Drug: Riluzole; Drug: Placebo
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute of Mental Health (NIMH)
Recruiting - verified June 2011 - Condition: Breast Cancer
Intervention: Drug: VPA FEC100
Sponsors: University of California, San Francisco; University of California, San Francisco; H. Lee Moffitt Cancer Center and Research Institute
Recruiting - verified March 2012 - Condition: High Grade Sarcoma
Intervention: Drug: Valproic Acid
Sponsors: Columbia University; Columbia University
Recruiting - verified October 2011 - Condition: Cancer
Intervention: Drug: Valproic Acid
Sponsors: University of Utah; University of Utah
Recruiting - verified January 2012 - Condition: Hot Flashes
Intervention: Drug: Gabapentin
Sponsors: Abramson Cancer Center of the University of Pennsylvania; Abramson Cancer Center of the University of Pennsylvania
Recruiting - verified May 2012 - Condition: Idiopathic Intracranial Hypertension
Interventions: Drug: Acetazolamide; Drug: Placebo; Behavioral: Formal weight loss counselling program
Sponsors: St. Luke's-Roosevelt Hospital Center; St. Luke's-Roosevelt Hospital Center; National Eye Institute (NEI); University of Rochester; University of Iowa; University of California, Davis
Recruiting - verified May 2012 - Conditions: Neoplasms; Constipation; Opioid-Related Disorders
Intervention: Drug: Methylnaltrexone bromide
Sponsors: University of Vermont; University of Vermont
Recruiting - verified March 2012 - Conditions: Cannabis Dependence; Cannabis Withdrawal; Cognitive Deficits
Interventions: Drug: gabapentin 1200mg/day; Drug: Placebo
Sponsors: The Scripps Research Institute; The Scripps Research Institute
Recruiting - verified March 2012 - Condition: Partial Epilepsies
Intervention: Drug: Lacosamide
Sponsors: UCB, Inc.; UCB, Inc.
Recruiting - verified May 2012 - Condition: Postoperative Pain
Interventions: Drug: Gabapentin; Drug: pregabalin
Sponsors: Loma Linda University; Loma Linda University
Recruiting - verified March 2012 - Condition: Epilepsy
Intervention: Drug: Lacosamide
Sponsors: UCB, Inc.; UCB, Inc.
Recruiting - verified May 2012 - Condition: Alcohol Dependence
Interventions: Drug: Pregabalin; Drug: Duloxetine; Behavioral: Standardized behavioral therapy; Behavioral: Standardized behavioral therapy; Drug: Placebo; Behavioral: Standardized behavioral therapy
Sponsors: The Scripps Research Institute; The Scripps Research Institute; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified June 2011 - Condition: Epilepsy
Interventions: Drug: levetiracetam; Drug: Lamotrigine
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; UCB Young Investigator Research Program; National EpiFellows Foundation; UCB, Inc.; GlaxoSmithKline
Recruiting - verified December 2011 - Condition: Epilepsy
Intervention: Drug: Eslicarbazepine acetate
Sponsors: Sunovion; Sunovion
Recruiting - verified April 2012 - Conditions: Lumbar Radicular Pain; Failed Back Surgery Syndrome; Spinal Stenosis; Herniated Disc
Interventions: Drug: Pregabalin; Drug: Sugar Pill
Sponsors: Northwestern University; Northwestern University
Recruiting - verified March 2012 - Condition: Marijuana Abuse
Intervention: Drug: bupropion, diazepam, dronabinol, ramelteon (Investigational Drug)
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute on Drug Abuse (NIDA)
Recruiting - verified May 2009 - Conditions: Glial Cell Tumors; Malignant Gliomas; Glioblastoma Multiforme; Anaplastic Astrocytoma; Gliomatosis Cerebri; Gliosarcoma; Brainstem Glioma
Interventions: Drug: Valproic acid; Drug: Bevacizumab; Radiation: Radiation therapy
Sponsors: Baylor College of Medicine; Baylor College of Medicine
Recruiting - verified February 2012 - Condition: Epilepsy With Simple or Complex Partial Onset Seizures
Interventions: Drug: Eslicarbazepine acetate; Drug: Eslicarbazepine acetate
Sponsors: Sunovion; Sunovion
Recruiting - verified April 2012 - Condition: Lung Cancer
Intervention: Drug: Hydralazine and Valproic Acid
Sponsors: New Mexico Cancer Care Alliance; New Mexico Cancer Care Alliance
Recruiting - verified April 2012 - Conditions: Alcoholism; Alcohol Dependence; Alcohol Abuse
Interventions: Drug: topiramate; Drug: zonisamide; Drug: Levetiracetam; Drug: Placebo
Sponsors: Boston Medical Center; Boston Medical Center; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified May 2011 - Condition: Seizures
Interventions: Drug: Bumetanide; Other: Normal Saline
Sponsors: Jensen, Frances, M.D.; Jensen, Frances, M.D.; Citizens United for Research in Epilepsy; Charles H. Hood Foundation; National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified January 2012 - Conditions: Bipolar Disorder; Anxiety Disorders; Bipolar Affective Disorder; Bipolar Depression
Intervention: Drug: Riluzole
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Mental Health (NIMH)
Recruiting - verified July 2011 - Condition: Bipolar Disorder
Intervention: Drug: lamictal
Sponsors: GlaxoSmithKline; GlaxoSmithKline
Recruiting - verified April 2012 - Conditions: Alcohol Dependence; Anxiety Disorder
Intervention: Drug: disulfiram plus lorazepam
Sponsors: University of New Mexico; University of New Mexico; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified January 2012 - Condition: Opioid-Induced Constipation
Interventions: Drug: Methylnaltrexone bromide; Drug: Placebo
Sponsors: Salix Pharmaceuticals; Salix Pharmaceuticals; Progenics Pharmaceuticals, Inc.
Recruiting - verified January 2012 - Condition: Opioid-Induced Constipation
Intervention: Drug: Methylnaltrexone bromide
Sponsors: Salix Pharmaceuticals; Salix Pharmaceuticals; Progenics Pharmaceuticals, Inc.
Recruiting - verified January 2012 - Conditions: Breast Cancer; Depression; Hot Flashes; Psychosocial Effects of Cancer and Its Treatment
Interventions: Drug: citalopram hydrobromide; Drug: escitalopram oxalate; Drug: gabapentin; Drug: sertraline hydrochloride; Drug: tamoxifen citrate; Drug: venlafaxine; Genetic: molecular genetic technique; Other: high performance liquid chromatography; Other: laboratory biomarker analysis; Other: pharmacological study; Procedure: adjuvant therapy
Sponsors: Mayo Clinic; Mayo Clinic; National Cancer Institute (NCI)
Recruiting - verified April 2012 - Condition: Alcohol Drinking
Interventions: Drug: topiramate; Drug: placebo
Sponsors: University of Connecticut Health Center; University of Connecticut Health Center; National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Center for Research Resources (NCRR)
Recruiting - verified December 2011 - Condition: Status Epilepticus
Intervention: Drug: lorazepam or diazepam
Sponsors: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - verified February 2012 - Condition: Traumatic Brain Injury
Interventions: Drug: Carbamazepine; Drug: Placebo
Sponsors: Carolinas Healthcare System; Carolinas Healthcare System; U.S. Department of Education
Recruiting - verified February 2012 - Conditions: Diabetic Neuropathic Pain; Chronic Low Back Pain
Interventions: Drug: donepezil; Drug: duloxetine; Drug: donepezil 2.5 mg and duloxetine 30mg; Drug: placebo; Drug: gabapentin
Sponsors: Wake Forest University; Wake Forest University; National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified February 2012 - Condition: Chronic Pain
Intervention:
Sponsors: Rush University Medical Center; Asokumar Buvanendran
Recruiting - verified April 2012 - Condition: Sleep-Related Eating Disorder
Intervention: Drug: Topiramate or Placebo
Sponsors: Brigham and Women's Hospital; Brigham and Women's Hospital
Recruiting - verified July 2011 - Condition: Recurrent Glioblastoma
Interventions: Drug: enzastaurin; Drug: bevacizumab
Sponsors: Eli Lilly and Company; Eli Lilly and Company; Genentech
Recruiting - verified October 2011 - Conditions: Bipolar Disorder; Bipolar Depression
Interventions: Drug: citalopram + mood stabilizer; Procedure: FDG PET scans; Procedure: MRI structural scans; Procedure: Genotyping; Procedure: Blood Draw; Drug: placebo + mood stabilizer
Sponsors: Tufts Medical Center; Tufts Medical Center; National Institute of Mental Health (NIMH)
Recruiting - verified July 2011 - Condition: Advanced Cancer
Interventions: Drug: Valproic Acid; Drug: Bevacizumab
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center
Recruiting - verified February 2012 - Conditions: Obsessive-compulsive Disorder; Ocd
Interventions: Drug: riluzole; Drug: placebo
Sponsors: Yale University; Yale University
Recruiting - verified January 2012 - Condition: Solid Tumors
Interventions: Drug: Dasatinib; Drug: Erlotinib; Drug: Lapatinib; Drug: Lenalidomide; Drug: Sorafenib; Drug: Sunitinib; Drug: Valproic Acid
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center
Recruiting - verified December 2011 - Condition: Sickle Cell Disease
Interventions: Biological: G-CSF; Drug: cyclophosphamide; Drug: fludarabine phosphate; Drug: mycophenolate mofetil; Drug: Sirolimus; Procedure: Allogeneic bone marrow transplantation; Radiation: total-body irradiation; Drug: Levetiracetam
Sponsors: Sidney Kimmel Comprehensive Cancer Center; Sidney Kimmel Comprehensive Cancer Center; National Cancer Institute (NCI)
Recruiting - verified May 2012 - Condition: Epilepsies, Partial
Intervention: Drug: Pregabalin
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Conditions: Alcohol Dependence; Cocaine Dependence
Interventions: Drug: Topiramate + Cognitive Behavioral Therapy; Drug: Placebo + Cognitive Behavioral Therapy
Sponsors: University of Virginia; Bankole Johnson; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Condition: Epilepsies, Partial
Interventions: Drug: Placebo; Drug: Pregabalin
Sponsors: Pfizer; Pfizer
Recruiting - verified April 2012 - Condition: Fibromyalgia
Intervention: Drug: Neurotropin
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Nursing Research (NINR)
Recruiting - verified October 2011 - Condition: Epilepsies, Partial
Interventions: Drug: Lyrica (pregabalin); Drug: placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified April 2012 - Conditions: Birth Defects; Pregnancy Complications; Epilepsy; Seizures
Intervention:
Sponsors: INC Research; INC Research; UCB, Inc.
Recruiting - verified March 2012 - Conditions: High Grade Gliomas; Brain Tumors
Interventions: Procedure: adjuvant therapy; Drug: Temozolomide; Drug: Valporic Acid; Radiation: Radiation therapy
Sponsors: National Institutes of Health Clinical Center (CC); National Cancer Institute (NCI)
Recruiting - verified March 2012 - Conditions: Tachycardia; Chronic Orthostatic Intolerance
Interventions: Drug: Acetazolamide; Drug: Atomoxetine; Other: Baseline (No Drug); Drug: Clonidine; Drug: Entacapone; Drug: Entacapone & Propranolol; Drug: Atomoxetine & Propranolol; Drug: Indomethacin; Drug: Mecamylamine; Drug: Isosorbide Dinitrate; Dietary Supplement: Melatonin; Drug: Midodrine; Drug: Modafinil; Drug: Octreotide; Radiation: Placebo; Drug: Propranolol; Drug: Modafinil & Propranolol; Drug: Sertraline; Procedure: IV Saline; Other: Drinking Water; Device: Breathing Device; Drug: memantine; Device: Abdominal binder
Sponsors: Vanderbilt University; Satish R. Raj; National Institutes of Health (NIH)
Recruiting - verified February 2012 - Conditions: Chronic Myeloproliferative Disorders; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Neoplasms; Precancerous Condition
Interventions: Biological: therapeutic allogeneic lymphocytes; Drug: busulfan; Drug: cyclosporine; Drug: fludarabine phosphate; Drug: mycophenolate mofetil; Procedure: peripheral blood stem cell transplantation; Radiation: Total Body Irradiation (TBI); Drug: Granulocyte colony-stimulating factor (G-CSF); Drug: Phenytoin; Drug: Methotrexate
Sponsors: OHSU Knight Cancer Institute; OHSU Knight Cancer Institute; National Cancer Institute (NCI)
Recruiting - verified March 2012 - Conditions: Autonomic Failure; Orthostatic Hypotension
Interventions: Drug: Atomoxetine; Drug: Acarbose; Drug: Pyridostigmine Bromide; Drug: Yohimbine; Drug: Midodrine HCl; Drug: placebo; Drug: Modafinil; Drug: Octreotide; Other: water intake; Drug: Diphenhydramine Hydrochloride; Drug: Ranitidine HCL; Drug: Tranylcypromine; Drug: Ergotamine/ Caffeine; Drug: Celecoxib; Drug: Pseudoephedrine; Drug: Methylphenidate; Drug: Indomethacin; Drug: Ibuprofen; Drug: Oxymetazoline 0.05% nasal solution; Dietary Supplement: Bovril; Drug: Acetazolamide; Drug: Rivastigmine tartrate; Drug: Carbidopa/levodopa; Device: abdominal binder; Device: abdominal binder (sham)
Sponsors: Vanderbilt University; Vanderbilt University
Recruiting - verified May 2012 - Condition: Abruptio Placentae
Intervention: Drug: magnesium sulfate, Normal Saline
Sponsors: Stanford University; Stanford University
Recruiting - verified April 2012 - Condition: Schizophrenia
Interventions: Drug: Tiagabine; Drug: Placebo
Sponsors: Beth Israel Deaconess Medical Center; Beth Israel Deaconess Medical Center; Dartmouth-Hitchcock Medical Center
Recruiting - verified July 2011 - Conditions: Depression; Major Depression/Bipolar Disorder
Interventions: Drug: Ketamine; Drug: Riluzole; Drug: FDG
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Mental Health (NIMH)
Recruiting - verified January 2012 - Condition: Cerebrovascular Accident
Interventions: Drug: Magnesium Sulfate; Drug: Normal Saline
Sponsors: University of California, Los Angeles; Jeffrey L. Saver; National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified December 2011 - Condition: Bipolar Disorder
Intervention: Drug: Riluzole
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Mental Health (NIMH)
Recruiting - verified June 2011 - Condition: Epilepsy
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified January 2012 - Conditions: CRPS-II (Causalgia); CRPS-I Reflex Sympathetic Dystrophy
Intervention: Drug: Neurotropin
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Nursing Research (NINR)
Recruiting - verified July 2011 - Condition: Alcoholism
Interventions: Drug: ondansetron + cognitive behavioral therapy; Drug: topiramate + cognitive behavioral therapy; Drug: Placebo + cognitive behavioral therapy; Drug: ondansetron + topiramate + cognitive behavioral therapy
Sponsors: University of Virginia; Bankole Johnson; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified February 2012
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Anticonvulsants Clinical Trials |
