- Conditions: Obesity; Overweight
Interventions: Drug: NB32; Drug: PBO; Behavioral: Weight Management Program
Sponsors: Orexigen Therapeutics, Inc; Orexigen Therapeutics, Inc
Not yet recruiting - verified May 2012 - Condition: Cigarette Smoking
Interventions: Drug: Nicotine replacement therapy - transdermal nicotine patch; Behavioral: Tailored behavioral intervention; Behavioral: Tobacco quitline referral; Drug: Nicotine replacement therapy - nicotine gum; Drug: Nicotine replacement therapy - nicotine lozenge; Drug: Bupropion SR; Drug: Varenicline; Drug: Combination pharmacotherapy - transdermal nicotine patch + nicotine gum; Drug: Combination pharmacotherapy - transdermal nicotine patch + nicotine lozenge; Drug: Combination pharmacotherapy - transdermal nicotine patch + bupropion; Behavioral: Alcohol use risk reduction; Behavioral: Behavioral activation for the treatment of depression; Behavioral: Behavioral management of post-cessation weight gain
Sponsors: University of Iowa; University of Iowa; Department of Veterans Affairs
Not yet recruiting - verified May 2012 - Conditions: Depressive Disorder; Depressive Disorder, Major; Depression
Intervention: Other: Citalopram
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Mental Health (NIMH)
Recruiting - verified March 2012 - Conditions: Cigarette Smoking; Nicotine Dependence
Interventions: Drug: varenicline (Chantix); Drug: bupropion (Zyban) & nicotine patches; Drug: nicotine patches
Sponsors: Duke University; Duke University; Philip Morris USA, Inc.
Recruiting - verified May 2012 - Conditions: MDD; Citalopram; Major Depressive Disorder
Intervention: Drug: citalopram
Sponsors: Mclean Hospital; Mclean Hospital
Recruiting - verified April 2012 - Condition: Hot Flashes in Men With Prostate Cancer Receiving Androgen Ablation Therapy
Interventions: Drug: Gabapentin; Drug: Venlafaxine
Sponsors: University of Wisconsin, Madison; University of Wisconsin, Madison
Recruiting - verified February 2012 - Condition: Spinal Cord Injury
Interventions: Drug: escitalopram oxalate; Drug: Cyproheptadine; Drug: sugar pill; Other: Graded intensity exercise
Sponsors: Rehabilitation Institute of Chicago; T. George Hornby; University of Medicine and Dentistry New Jersey; Rehabilitation Institute of Chicago
Recruiting - verified February 2012 - Condition: Depression
Interventions: Behavioral: Sleep scheduling; Drug: Fluoxetine
Sponsors: University of Michigan; University of Michigan
Recruiting - verified March 2012 - Condition: Anorexia
Interventions: Drug: megestrol acetate; Drug: Arm B (megestrol plus mirtazapine)
Sponsors: Washington University School of Medicine; Washington University School of Medicine
Recruiting - verified April 2012 - Condition: Bipolar I Disorder
Intervention: Drug: Lithium/Matching Placebo and an SGA (Second Generation Antipsychotic)
Sponsors: North Shore Long Island Jewish Health System; North Shore Long Island Jewish Health System; National Institutes of Health (NIH)
Recruiting - verified December 2011 - Condition: Major Depressive Disorder
Interventions: Drug: Placebo; Drug: Vilazodone; Drug: Vilazodone; Drug: Citalopram
Sponsors: Forest Laboratories; Forest Laboratories
Recruiting - verified March 2012 - Condition: Cocaine Dependence
Interventions: Drug: Citalopram; Drug: Citalopram; Drug: Placebo
Sponsors: The University of Texas Health Science Center, Houston; Joy Schmitz; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Condition: Smoking Cessation
Interventions: Drug: Placebo; Drug: varenicline tartrate; Drug: bupropion hydrochloride; Drug: Nicotine Replacement Therapy Patch
Sponsors: Pfizer; Pfizer; GlaxoSmithKline
Recruiting - verified May 2012 - Condition: Major Depressive Disorder
Interventions: Drug: Antidepressant + SPD489 (Lisdexamfetamine dimesylate ); Drug: Antidepressant + Placebo
Sponsors: Shire Development LLC; Shire Development LLC
Recruiting - verified March 2012 - Condition: Major Depressive Disorder
Interventions: Drug: SPD489 (Lisdexamfetamine dimesylate ); Drug: Placebo
Sponsors: Shire Development LLC; Shire Development LLC
Recruiting - verified May 2012 - Condition: Bipolar Depression
Interventions: Drug: ESC + CBX; Drug: ESC + PBO.; Drug: ESC+CBX
Sponsors: Loyola University; Loyola University; Stanley Medical Research Institute
Recruiting - verified December 2011 - Condition: Major Depressive Disorder
Intervention: Drug: Escitalopram
Sponsors: Wyss Institute at Harvard University; Wyss Institute at Harvard University; Massachusetts General Hospital; Martinos Center for Biomedical Imaging; Massachusetts Institute of Technology
Recruiting - verified April 2012 - Conditions: Hot Flashes; Menopause; Vasomotor Disturbance
Interventions: Drug: Low-dose 17-ß-estradiol; Drug: Venlafaxine XR; Drug: Placebo
Sponsors: Fred Hutchinson Cancer Research Center; Fred Hutchinson Cancer Research Center; National Institute on Aging (NIA); Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); National Center for Complementary and Alternative Medicine (NCCAM); Office of Research on Women's Health (ORWH)
Recruiting - verified December 2011 - Condition: Major Depressive Disorder
Interventions: Drug: Augmenting: Antidepressant + Aripiprazole; Drug: Augmenting: Antidepressant + Bupropion-SR; Drug: Switching: Bupropion-SR
Sponsors: Department of Veterans Affairs; Department of Veterans Affairs
Not yet recruiting - verified March 2012 - Condition: Body Dysmorphic Disorder
Intervention: Procedure: PET scan and MRI scan
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified January 2012 - Condition: Nicotine Dependence
Interventions: Drug: Varenicline; Drug: Bupropion; Drug: Nicotine patches
Sponsors: Duke University; Duke University; National Institute on Drug Abuse (NIDA)
Recruiting - verified January 2012 - Condition: Major Depressive Disorder
Interventions: Drug: desvenlafaxine succinate sustained release; Drug: fluoxetine; Drug: placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Conditions: Pregnancy Related; Tobacco Use Disorder
Interventions: Drug: bupropion SR 150 mg tablets or matched placebo; Behavioral: Smoking Cessation Counseling
Sponsors: The University of Texas, Galveston; The University of Texas, Galveston; National Institute on Drug Abuse (NIDA); University of Connecticut Health Center
Recruiting - verified August 2011 - Condition: Depression
Interventions: Drug: Duloxetine; Drug: Escitalopram; Drug: BMS-820836 Placebo; Drug: BMS-820836; Drug: BMS-820836; Drug: BMS-820836; Drug: BMS-820836
Sponsors: Bristol-Myers Squibb; Bristol-Myers Squibb
Recruiting - verified August 2011 - Condition: Treatment Outcome
Interventions: Drug: Lu AA21004; Drug: Escitalopram
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Global Research & Development Center, Inc.
Recruiting - verified May 2012 - Conditions: TBI; Major Depression; Other Psychiatric Disorders
Intervention: Drug: Escitalopram
Sponsors: Johns Hopkins University; Johns Hopkins University; Forest Laboratories
Recruiting - verified February 2009 - Condition: Methamphetamine Dependence
Interventions: Other: placebo; Drug: Naltrexone and Bupropion SR
Sponsors: National Institute on Drug Abuse (NIDA); National Institute on Drug Abuse (NIDA)
Recruiting - verified August 2011 - Conditions: Drug-Drug Interaction; Healthy Volunteers
Intervention: Drug: Fluoxetine
Sponsors: University of Washington; University of Washington; National Institute of General Medical Sciences (NIGMS)
Recruiting - verified April 2012 - Condition: Bipolar Disorder
Interventions: Drug: Lithium; Drug: Quetiapine
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; Agency for Healthcare Research and Quality (AHRQ)
Recruiting - verified April 2012 - Condition: Major Depressive Disorder
Interventions: Drug: PNB01 fixed dose combination of pipamperone and citalopram; Drug: Citalopram; Drug: Pipamperone
Sponsors: PharmaNeuroBoost N.V.; PharmaNeuroBoost N.V.
Recruiting - verified March 2012 - Condition: Nicotine Dependence
Interventions: Drug: Varenicline; Drug: Bupropion; Drug: Nicotine patches; Drug: Nicotine Inhaler
Sponsors: Duke University; Duke University; National Institute on Drug Abuse (NIDA); Philip Morris USA, Inc.
Recruiting - verified March 2012 - Conditions: Smoking; Smoking Cessation
Interventions: Other: Coordinated Care; Other: Usual Care
Sponsors: University of Pittsburgh; University of Pittsburgh; National Institutes of Health (NIH); National Cancer Institute (NCI)
Recruiting - verified September 2011 - Condition: Smoking Cessation
Intervention: Drug: Bupropion SR
Sponsors: The University of Texas Health Science Center, Houston; The University of Texas Health Science Center, Houston; M.D. Anderson Cancer Center; Larry C. Gilstrap, MD Center for Perinatal and Women's Health Research; The Center for Clinical and Translational Sciences (CCTS) Clinical Research Unit at The University of Texas Health Science Center at Houston
Recruiting - verified February 2012 - Condition: Major Depressive Disorder (MDD)
Interventions: Drug: Amisulpride; Drug: Placebo
Sponsors: Mclean Hospital; Mclean Hospital; National Institute of Mental Health (NIMH)
Recruiting - verified March 2012 - Conditions: Depression; Asthma
Interventions: Drug: Escitalopram; Drug: Placebo
Sponsors: University of Texas Southwestern Medical Center; University of Texas Southwestern Medical Center; National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified March 2012 - Condition: Smoking Cessation
Intervention: Behavioral: counseling vs. advice
Sponsors: University of Alabama at Birmingham; University of Alabama at Birmingham; National Cancer Institute (NCI)
Recruiting - verified February 2012 - Condition: Head And Neck Cancer
Interventions: Other: Placebo; Drug: Curcumin; Drug: Armodafinil; Drug: Minocycline; Drug: Bupropion
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center; National Cancer Institute (NCI)
Not yet recruiting - verified November 2011 - Condition: Major Depressive Disorder
Intervention: Drug: Escitalopram
Sponsors: Forest Laboratories; Forest Laboratories
Recruiting - verified February 2012 - Condition: Posttraumatic Stress Disorder
Interventions: Drug: Mirtazapine; Drug: Sertraline; Other: Sugar pill
Sponsors: Research Foundation for Mental Hygiene; Research Foundation for Mental Hygiene; National Institute of Mental Health (NIMH)
Recruiting - verified July 2010 - Condition: Alcohol Dependence
Interventions: Drug: Quetiapine XR plus mirtazapine; Drug: Quetiapine fumarate extended release (Quetiapine XR)
Sponsors: Dartmouth-Hitchcock Medical Center; Dartmouth-Hitchcock Medical Center
Recruiting - verified February 2012 - Conditions: Complicated Grief; Bereavement
Interventions: Drug: Citalopram; Behavioral: Complicated Grief Treatment; Other: Placebo
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute of Mental Health (NIMH); American Foundation for Suicide Prevention
Recruiting - verified March 2012 - Conditions: Depression; Back Pain
Interventions: Other: Combination Treatment with Higher-dose venlafaxine + PST-DP; Drug: Higher-dose venlafaxine and supportive management
Sponsors: University of Pittsburgh; University of Pittsburgh
Recruiting - verified March 2012 - Conditions: Schizophrenia; Smoking Cessation
Interventions: Other: Sugar Pill; Drug: Varenicline; Drug: Bupropion HCl
Sponsors: University of Minnesota - Clinical and Translational Science Institute; University of Minnesota - Clinical and Translational Science Institute; National Institutes of Health (NIH); National Institute on Drug Abuse (NIDA)
Recruiting - verified August 2011 - Condition: Nicotine Dependence
Interventions: Drug: Bupropion SR; Drug: Nicotine; Drug: Placebo pill and Placebo Patch; Other: Delayed-Quit Control
Sponsors: Southern Illinois University Carbondale; Southern Illinois University Carbondale; National Institute on Drug Abuse (NIDA)
Recruiting - verified September 2011 - Condition: Breast Cancer
Interventions: Biological: Ad.p53 DC vaccine; Drug: 1-methyl-D-tryptophan (1-MT)
Sponsors: H. Lee Moffitt Cancer Center and Research Institute; H. Lee Moffitt Cancer Center and Research Institute; National Cancer Institute (NCI)
Recruiting - verified February 2012 - Conditions: Schizophrenia; Schizophreniform Disorder
Interventions: Drug: Citalopram; Behavioral: Psychoeducation; Behavioral: Cognitive Behavioral Therapy (CBT); Radiation: Functional Magnetic Resonance Imaging (fMRI); Drug: Placebo; Behavioral: Psychoeducation; Behavioral: Cognitive Behavioral Therapy (CBT); Radiation: Functional Magnetic Resonance Imaging (fMRI)
Sponsors: National Institute of Mental Health (NIMH); National Institute of Mental Health (NIMH)
Recruiting - verified December 2011 - Condition: Depression
Interventions: Drug: lithium and Venlafaxine; Procedure: ECT
Sponsors: Mount Sinai School of Medicine; Mount Sinai School of Medicine; National Institute of Mental Health (NIMH)
Recruiting - verified March 2012 - Condition: Hot Flashes
Interventions: Drug: venlafaxine; Drug: placebo; Procedure: hypnotherapy; Procedure: mind-body intervention procedure
Sponsors: Mayo Clinic; Mayo Clinic; National Cancer Institute (NCI)
Recruiting - verified April 2012 - Condition: Major Depressive Disorder With Psychotic Features
Interventions: Drug: Quetiapine monotherapy; Drug: Quetiapine with SSRI
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified February 2012 - Condition: Major Depressive Disorder
Intervention: Drug: escitalopram and adjunctive aripiprazole and placebo
Sponsors: Washington University School of Medicine; Washington University School of Medicine
Recruiting - verified August 2011 - Condition: Smoking Cessation
Interventions: Drug: Varenicline; Drug: Bupropion; Other: Placebo; Behavioral: Counseling/Phone Calls
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center; National Institutes of Health (NIH); National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2012 - Conditions: Alzheimer's Disease; Agitation
Interventions: Drug: citalopram; Drug: placebo
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute on Aging (NIA); National Institute of Mental Health (NIMH)
Recruiting - verified May 2012 - Condition: Marijuana Abuse
Intervention: Drug: bupropion, diazepam, dronabinol, ramelteon (Investigational Drug)
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute on Drug Abuse (NIDA)
Recruiting - verified May 2009 - Condition: Short Bowel Syndrome
Intervention: Drug: Citalopram
Sponsors: University of Nebraska; University of Nebraska
Recruiting - verified August 2011 - Condition: Major Depressive Disorder
Intervention: Drug: Creatine Monohydrate
Sponsors: University of Utah; University of Utah; AlzChem, LLC
Recruiting - verified April 2012 - Condition: Postpartum Depression
Intervention: Drug: Escitalopram
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; Forest Laboratories
Recruiting - verified July 2011 - Conditions: Mood Disorder; Mental Disorder Diagnosed in Childhood; Attention Deficit and Disruptive Behavior Disorder; Attention Deficit Hyperactivity Disorder
Interventions: Drug: Citalopram; Drug: Methylphenidate
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Mental Health (NIMH)
Recruiting - verified July 2011 - Conditions: Breast Cancer; Lung Cancer; Melanoma; Pancreatic Cancer; Solid Tumors
Intervention: Drug: 1-methyl-D-tryptophan
Sponsors: NewLink Genetics Corporation; NewLink Genetics Corporation
Recruiting - verified December 2011 - Condition: Depression
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Mental Health (NIMH)
Recruiting - verified December 2011 - Condition: Major Depressive Disorder
Interventions: Drug: Escitalopram; Drug: Sertraline; Drug: Venlafaxine XR
Sponsors: BRC Operations Pty. Ltd.; BRC Operations Pty. Ltd.
Recruiting - verified March 2012 - Conditions: Breast Cancer; Depression; Hot Flashes; Psychosocial Effects of Cancer and Its Treatment
Interventions: Drug: citalopram hydrobromide; Drug: escitalopram oxalate; Drug: gabapentin; Drug: sertraline hydrochloride; Drug: tamoxifen citrate; Drug: venlafaxine; Genetic: molecular genetic technique; Other: high performance liquid chromatography; Other: laboratory biomarker analysis; Other: pharmacological study; Procedure: adjuvant therapy
Sponsors: Mayo Clinic; Mayo Clinic; National Cancer Institute (NCI)
Recruiting - verified April 2012 - Conditions: Stress Disorders, Posttraumatic; Tobacco Use Disorder
Interventions: Drug: Nicotine; Behavioral: Cognitive Behavioral Therapy for Smoking Cessation; Drug: Bupropion SR
Sponsors: Department of Veterans Affairs; Department of Veterans Affairs
Recruiting - verified March 2012 - Condition: Depression
Intervention: Drug: citalopram and escitalopram
Sponsors: Mayo Clinic; Mayo Clinic; National Institutes of Health (NIH)
Recruiting - verified May 2012 - Condition: Alcohol Drinking
Interventions: Drug: varenicline; Drug: bupropion; Drug: placebo
Sponsors: Yale University; Yale University
Recruiting - verified January 2012 - Condition: Smoking Lapse Behavior
Interventions: Drug: varenicline; Drug: bupropion; Drug: Placebo
Sponsors: Yale University; Yale University
Recruiting - verified January 2012 - Conditions: Bipolar Disorder; Bipolar Depression
Interventions: Drug: citalopram + mood stabilizer; Procedure: FDG PET scans; Procedure: MRI structural scans; Procedure: Genotyping; Procedure: Blood Draw; Drug: placebo + mood stabilizer
Sponsors: Tufts Medical Center; Tufts Medical Center; National Institute of Mental Health (NIMH)
Recruiting - verified July 2011 - Conditions: Advanced Cancer; Weight Loss
Intervention: Drug: Olanzapine
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center
Recruiting - verified May 2012 - Condition: Depression
Interventions: Drug: Escitalopram; Drug: Desipramine
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute of Mental Health (NIMH)
Recruiting - verified April 2012 - Condition: Depression
Interventions: Drug: Paroxetine CR for major depressive episode; Drug: Bupropion XL for major depressive episode
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute of Mental Health (NIMH)
Recruiting - verified February 2012 - Condition: Depression
Interventions: Drug: Escitalopram; Drug: Duloxetine; Behavioral: Cognitive behavioral therapy (CBT)
Sponsors: National Institute of Mental Health (NIMH); National Institute of Mental Health (NIMH); Emory University
Recruiting - verified December 2011 - Condition: Functional Dyspepsia
Interventions: Drug: Amitriptyline; Drug: escitalopram; Drug: placebo
Sponsors: Mayo Clinic; Mayo Clinic; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified January 2012 - Conditions: Cocaine Dependence; Depression
Interventions: Drug: Mirtazapine; Drug: Placebo
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute on Drug Abuse (NIDA)
Recruiting - verified October 2011 - Condition: Body Dysmorphic Disorder
Interventions: Drug: Fluoxetine; Drug: Placebo
Sponsors: Montefiore Medical Center; Montefiore Medical Center; Food and Drug Administration (FDA)
Recruiting - verified September 2011 - Conditions: Anxiety Disorders; Somatoform Disorders
Interventions: Drug: Escitalopram; Drug: Placebo; Drug: Escitalopram extension
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; National Institute of Mental Health (NIMH); Rhode Island Hospital
Recruiting - verified May 2012 - Condition: Depressive Disorder, Major
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Mental Health (NIMH)
Recruiting - verified October 2011 - Conditions: Depression; Mood Disorder; Anxiety Disorder; Healthy
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Mental Health (NIMH)
Recruiting - verified October 2011
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Antidepressive Agents Second Generation Clinical Trials |
