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Antioxidants

Antioxidants

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  • N-Acetylcysteine for Patients With COPD and ChronicBronchitis

    Conditions:   Chronic Obstructive Pulmonary Disease;   Chronic Bronchitis
    Interventions:   Drug: N-acetylcysteine;   Drug: Oral acetylcysteine
    Sponsors:   Minnesota Veterans Research Institute;   Minnesota Veterans Research Institute
    Not yet recruiting - verified May 2012
  • Circadian Rhythm of Melatonin in Burns

    Conditions:   Sleep;   Burns
    Intervention:  
    Sponsors:   Shriners Hospitals for Children;   Shriners Hospitals for Children;   Children's Hospital Medical Center, Cincinnati
    Recruiting - verified May 2012
  • Diagnosis and Treatment of Dyssomnia in Children During Burn Rehabilitation

    Condition:   Pediatric Burns
    Interventions:   Drug: Melatonin;   Other: placebo
    Sponsors:   Shriners Hospitals for Children;   Shriners Hospitals for Children
    Not yet recruiting - verified May 2012
  • The Effects of Antioxidants in Blueberry Powder on Inflammation Induced by a Single High Fat Meal.

    Condition:   Inflammation
    Interventions:   Other: Breakfast meal with placebo powder;   Other: Breakfast meal with 1 serving equivalent of blueberries;   Other: Breakfast meal with 2 serving equivalents of blueberries;   Other: Breakfast meal with 4 serving equivalents of blueberries
    Sponsors:   USDA, Western Human Nutrition Research Center;   USDA, Western Human Nutrition Research Center;   US Highbush Blueberry Council
    Recruiting - verified May 2012
  • Resveratrol-Leucine Metabolite Synergy in Pre-diabetes

    Condition:   Impaired Glucose Tolerance
    Interventions:   Dietary Supplement: Resveratrol;   Dietary Supplement: resveratrol /HMB;   Other: Placebo treatment
    Sponsors:   Vanderbilt University;   Vanderbilt University;   Nutraceutical Discoveries, Inc.
    Recruiting - verified May 2012
  • High Dose Vitamin C in the Critically Ill Patient

    Condition:   Shock
    Interventions:   Drug: Ascorbic Acid;   Other: Ringers Lactate or Normal Saline
    Sponsors:   University of Medicine and Dentistry New Jersey;   University of Medicine and Dentistry New Jersey
    Not yet recruiting - verified February 2012
  • Study of the Safety and Efficacy of Zoenasa® Versus Mesalamine Enema in Subjects With Left-Sided Ulcerative Colitis

    Conditions:   Ulcerative Colitis;   Left-sided Ulcerative Colitis;   Distal Ulcerative Colitis
    Interventions:   Drug: Zoenasa-1:4;   Drug: Mesalamine Enema
    Sponsors:   Altheus Therapeutics, Inc.;   Altheus Therapeutics, Inc.
    Not yet recruiting - verified April 2012
  • Investigating the Effects of Evening Light Exposure on Melatonin Suppression, Alertness and Nocturnal Sleep

    Condition:   Melatonin Suppression
    Intervention:   Radiation: Visible light
    Sponsors:   Brigham and Women's Hospital;   Brigham and Women's Hospital;   Biological Illumination LCC
    Not yet recruiting - verified April 2012
  • Vitamin C for Severe Thermal Injuries

    Condition:   Severe Thermal Injury, Greater Than 20% TBSA
    Interventions:   Drug: High Dose Ascorbic Acid;   Drug: Placebo
    Sponsors:   University of Texas Southwestern Medical Center;   University of Texas Southwestern Medical Center
    Not yet recruiting - verified April 2012
  • Vitamin C and Atrial Fibrillation After Cardiac Surgery

    Condition:   Atrial Fibrillation
    Interventions:   Drug: Ascorbic Acid;   Other: Identical Placebo
    Sponsors:   Regional Hospital of Scranton;   Regional Hospital of Scranton
    Not yet recruiting - verified April 2012
  • Efficacy Of Tocotrienol a Natural Vitamin E In Biopsy Wound

    Condition:   Scar
    Intervention:  
    Sponsors:   Ohio State University;   Chandan K Sen;   Carotech Inc.
    Recruiting - verified April 2012
  • Testosterone Pellets Plus Vitamin D and E Versus Vitamin D and E Alone for the Treatment of Peyronie's Disease

    Condition:   Peyronie's Disease
    Interventions:   Drug: Vitamin D2;   Drug: Vitamin E;   Drug: Testosterone Pellets
    Sponsors:   Men's Health Boston;   Men's Health Boston
    Recruiting - verified April 2012
  • A Pilot Study of Allopurinol to Prevent Kidney Function Loss in Type 1 Diabetes

    Condition:   Diabetic Nephropathies
    Interventions:   Drug: Allopurinol;   Drug: Placebo
    Sponsors:   Joslin Diabetes Center;   Alessandro Doria;   Steno Diabetes Center;   University of Michigan;   University of Minnesota - Clinical and Translational Science Institute
    Not yet recruiting - verified April 2012
  • A Placebo-controlled Trial of Daliresp on Chronic Obstructive Pulmonary Disease (COPD)

    Condition:   COPD
    Interventions:   Drug: roflumilast;   Drug: placebo
    Sponsors:   University of Alabama at Birmingham;   University of Alabama at Birmingham
    Not yet recruiting - verified April 2012
  • NUTRITION: Natural Tocotrienol Against Ischemic Stroke Event

    Conditions:   Ischemic Stroke;   Transient Ischemic Attack (TIA)
    Intervention:   Other: Vitamin E tocotrienol (TCT) pills ; Low dose Aspirin
    Sponsors:   Ohio State University;   Chandan K Sen;   Government of Malaysia
    Recruiting - verified April 2012
  • Bisphenol A Controlled Exposure Study

    Condition:   Healthy
    Intervention:   Other: deuterated-Bisphenol A (d-BPA)
    Sponsors:   National Institutes of Health Clinical Center (CC);   National Institute of Environmental Health Sciences (NIEHS)
    Recruiting - verified February 2011
  • Topical Sodium Thiosulfate and Fractional Carbon Dioxide Laser in Treating Dermatomyositis Associated Calcinosis

    Condition:   Dermatomyositis Associated Superficial Calcinosis
    Interventions:   Device: Fractional Carbon Dioxide (FCO2) Laser (Candela QuadraLase (TM));   Drug: Sodium thiosulfate
    Sponsors:   George Washington University;   George Washington University
    Not yet recruiting - verified April 2012
  • Pomegranate and Hemodialysis Pilot Trial

    Conditions:   End Stage Renal Disease;   Cardiovascular Disease;   Inflammation
    Interventions:   Other: Pomegranate juice;   Other: Pomegranate fruit extract
    Sponsors:   University of Washington;   University of Washington
    Recruiting - verified March 2012
  • Intra-arterial Versus Intravenous Cisplatin, Combined With Radiation, for Oral Cavity and Oropharynx Cancer

    Condition:   Head and Neck Cancer
    Interventions:   Drug: Intra-arterial cisplatin;   Drug: Intravenous cisplatin
    Sponsors:   Southern Illinois University;   Southern Illinois University
    Not yet recruiting - verified April 2012
  • Role of Flavanols in Exercise and Aging

    Condition:   Aging
    Interventions:   Dietary Supplement: High Flavanol Trial;   Dietary Supplement: Low Flavanol Trial;   Dietary Supplement: High Flavanol Trial; long-term;   Dietary Supplement: Low Flavanol Trial; long-term effects
    Sponsors:   University of Texas at Austin;   University of Texas at Austin
    Not yet recruiting - verified March 2012
  • Post Market Study of the 3DKnee™ With E-plus Insert

    Conditions:   Osteoarthritis;   Traumatic Arthritis;   Total Knee Joint Prosthesis
    Intervention:   Device: 3DKnee™ System with Vitamin E UHMWPE Tibial Inserts
    Sponsors:   Encore Medical, L.P.;   Encore Medical, L.P.;   DJO Incorporated
    Recruiting - verified May 2012
  • Systemic Markers of Collagen Metabolism and Vitamin C in Smokers and Non-Smokers With Pelvic Organ Prolapse

    Condition:   Pelvic Organ Prolapse
    Intervention:   Other: Blood draw for the study participants
    Sponsors:   TriHealth Inc.;   TriHealth Inc.
    Recruiting - verified March 2012
  • Rasburicase and Allopurinol in Treating Patients With Hematologic Malignancies

    Conditions:   Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities;   Adult Acute Myeloid Leukemia With Del(5q);   Adult Acute Myeloid Leukemia With Inv(16)(p13;q22);   Adult Acute Myeloid Leukemia With t(15;17)(q22;q12);   Adult Acute Myeloid Leukemia With t(16;16)(p13;q22);   Adult Acute Myeloid Leukemia With t(8;21)(q22;q22);   Blastic Phase Chronic Myelogenous Leukemia;   Contiguous Stage II Adult Burkitt Lymphoma;   de Novo Myelodysplastic Syndromes;   Noncontiguous Stage II Adult Burkitt Lymphoma;   Previously Treated Myelodysplastic Syndromes;   Recurrent Adult Acute Lymphoblastic Leukemia;   Recurrent Adult Acute Myeloid Leukemia;   Recurrent Adult Burkitt Lymphoma;   Stage I Adult Burkitt Lymphoma;   Stage III Adult Burkitt Lymphoma;   Stage IV Adult Burkitt Lymphoma;   Untreated Adult Acute Lymphoblastic Leukemia;   Untreated Adult Acute Myeloid Leukemia
    Interventions:   Drug: rasburicase;   Drug: allopurinol;   Drug: rasburicase
    Sponsors:   Roswell Park Cancer Institute;   Roswell Park Cancer Institute
    Recruiting - verified January 2012
  • Study of Chokeberry to Reduce Cardiovascular Disease Risk in Former Smokers

    Conditions:   Cardiovascular Disease;   Oxidative Stress
    Interventions:   Dietary Supplement: Chokeberry Extract;   Dietary Supplement: Placebo capsule;   Dietary Supplement: Chokeberry extract capsule, acute
    Sponsors:   University of Connecticut;   University of Connecticut
    Not yet recruiting - verified February 2012
  • A Research Study of Intravenous Vitamin C in Combination With Irinotecan Versus Irinotecan Alone for Advanced Colorectal Cancer

    Condition:   -kRAS Mutant Stage IV Colorectal Cancer
    Intervention:   Drug: Vitamin C
    Sponsors:   Thomas Jefferson University;   Thomas Jefferson University
    Recruiting - verified March 2012
  • Effects of Resveratrol Supplements on Vascular Health in Postmenopausal Women

    Condition:   Cardiovascular Disease
    Interventions:   Dietary Supplement: ResA;   Dietary Supplement: Resveratrol;   Dietary Supplement: Placebo
    Sponsors:   University of California, Davis;   University of California, Davis;   Gateway Health Alliance
    Not yet recruiting - verified March 2012
  • Assessing the Efficacy and Safety of Intravenous Vitamin C in Combination With Standard Chemotherapy for Pancreatic Cancer

    Condition:   Stage IV Pancreatic Cancer
    Intervention:   Drug: Ascorbic Acid
    Sponsors:   Thomas Jefferson University;   Thomas Jefferson University
    Recruiting - verified March 2012
  • Dietary Histone Deacetylase Inhibitors (HDAC)

    Condition:   HDAC Activity
    Interventions:   Dietary Supplement: Broccoli sprout extract (BSE) placebo;   Dietary Supplement: Broccoli sprout extract (BSE) capsules;   Dietary Supplement: garlic oil capsules;   Dietary Supplement: garlic oil placebo
    Sponsors:   Oregon State University;   Oregon State University
    Not yet recruiting - verified February 2012
  • Hypertrophic Regression With N-Acetylcysteine in HCM

    Condition:   Hypertrophic Cardiomyopathy
    Intervention:   Drug: N-acetylcysteine (NAC)
    Sponsors:   The University of Texas Health Science Center, Houston;   The University of Texas Health Science Center, Houston;   National Institutes of Health (NIH)
    Recruiting - verified February 2012
  • The Effect of Vitamin C on Growth Hormone Secretion

    Conditions:   Obese;   Disorder of Vitamin C;   Growth Hormone Secretion Abnormality
    Interventions:   Dietary Supplement: Placebo;   Dietary Supplement: Vitamin C 250 mg once daily;   Dietary Supplement: Vitamin C 1,000 mg once daily
    Sponsors:   Massachusetts General Hospital;   Massachusetts General Hospital
    Not yet recruiting - verified March 2012
  • Pilot Study About the Harmful Effects of Blood Storage on Overweight People and the Role of iNO in This Setting

    Conditions:   Blood Transfusion;   Endothelial Physiopathology;   Inflammation;   Hemoglobins;   Nitric Oxide
    Interventions:   Procedure: Red blood Cells auto-transfusion;   Procedure: Red blood Cells auto-transfusion;   Drug: Inhaled Nitric Oxide (iNO) administration
    Sponsors:   Massachusetts General Hospital;   Massachusetts General Hospital
    Recruiting - verified April 2012
  • Clinical Trial of High-dose Vitamin C for Advanced Pancreatic Cancer

    Conditions:   Pancreatic Neoplasms;   Pancreatic Cancer
    Intervention:   Drug: Gemcitabine with escalating ascorbic acid
    Sponsors:   University of Iowa;   University of Iowa;   Susan L Bader Foundation of Hope;   The Holden Comprehensive Cancer Center;   The National Cancer Institute (NCI)
    Not yet recruiting - verified May 2012
  • The Effect of an Oral Antioxidant, N-Acetyl-L-Cysteine, on Inflammatory and Oxidative Stress Markers in Pulmonary Sarcoidosis

    Condition:   Pulmonary Sarcoidosis
    Interventions:   Dietary Supplement: N-acetyl-cysteine;   Drug: Placebo
    Sponsors:   National Jewish Health;   National Jewish Health;   American Thoracic Society
    Recruiting - verified April 2012
  • Alpha-lipoic Acid/L-acetyl Carnitine for Progressive Supranuclear Palsy

    Condition:   Progressive Supranuclear Palsy
    Intervention:   Drug: alpha-lipoic acid and L-acetyl carnitine
    Sponsors:   Weill Medical College of Cornell University;   Weill Medical College of Cornell University
    Recruiting - verified February 2012
  • Combining Lesinurad With Allopurinol in Inadequate Responders

    Condition:   Gout
    Interventions:   Drug: Lesinurad;   Drug: Lesinurad;   Drug: Placebo
    Sponsors:   Ardea Biosciences, Inc.;   Ardea Biosciences, Inc.
    Recruiting - verified May 2012
  • Evaluation of the Use of Trental and Vitamin E For Prophylaxis of Radiation Necrosis

    Condition:   Brain Metastasis
    Interventions:   Drug: Trental;   Dietary Supplement: Vitamin E
    Sponsors:   University of Cincinnati;   University of Cincinnati
    Recruiting - verified January 2012
  • Effects of Pennsaid on Clinical Neuropathic Pain

    Conditions:   Neuralgia;   Postherpetic Neuralgia;   Reflex Sympathetic Dystrophy
    Interventions:   Drug: Pennsaid topical 1.5% diclofenac;   Drug: Placebo (2.3% DMSO solution)
    Sponsors:   Massachusetts General Hospital;   Massachusetts General Hospital
    Recruiting - verified March 2012
  • Study of Melatonin on Sleep, Pain, and Confusion After Joint Replacement Surgery

    Conditions:   Postoperative Pain;   Delirium;   Confusion;   Sleep
    Interventions:   Drug: Melatonin;   Drug: Placebo
    Sponsors:   Hospital for Special Surgery, New York;   Hospital for Special Surgery, New York
    Recruiting - verified March 2012
  • Resveratrol for Alzheimer's Disease

    Condition:   Alzheimer's Disease
    Interventions:   Drug: Resveratrol;   Drug: Placebo
    Sponsors:   Alzheimer's Disease Cooperative Study (ADCS);   Alzheimer's Disease Cooperative Study (ADCS);   National Institute on Aging (NIA)
    Recruiting - verified May 2012
  • Fluorescence-guided Surgery for Low- and High-grade Gliomas

    Condition:   Glioma
    Intervention:   Drug: 5-Aminolevulinic acid (ALA) or ascorbic acid (placebo)
    Sponsors:   St. Joseph's Hospital and Medical Center, Phoenix;   St. Joseph's Hospital and Medical Center, Phoenix
    Recruiting - verified January 2012
  • Se-Methyl-Seleno-L-Cysteine or Selenomethionine in Preventing Prostate Cancer in Healthy Participants

    Condition:   Prostate Cancer
    Interventions:   Dietary Supplement: Se-methyl-seleno-L-cysteine;   Dietary Supplement: selenomethionine;   Other: placebo
    Sponsors:   National Cancer Institute (NCI);   Robert H. Lurie Cancer Center;   National Cancer Institute (NCI)
    Recruiting - verified December 2011
  • Zonisamide for Heavy Drinkers With Bipolar Disorder

    Conditions:   Alcohol Use Disorders;   Bipolar Disorder
    Interventions:   Drug: Zonisamide;   Drug: Placebo
    Sponsors:   VA Connecticut Healthcare System;   VA Connecticut Healthcare System;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Not yet recruiting - verified May 2012
  • Combining Lesinurad With Allopurinol in Inadequate Responders

    Condition:   Gout
    Interventions:   Drug: Lesinurad;   Drug: Lesinurad;   Drug: Placebo
    Sponsors:   Ardea Biosciences, Inc.;   Ardea Biosciences, Inc.
    Recruiting - verified May 2012
  • Composites and Urinary Bisphenol-A Study

    Condition:   Dental Caries
    Intervention:   Procedure: Restoration of dental caries with dental composite or amalgam
    Sponsors:   New England Research Institutes;   New England Research Institutes;   National Institute of Environmental Health Sciences (NIEHS);   Harvard School of Public Health
    Not yet recruiting - verified December 2011
  • N-Acetylcysteine for Neuroprotection in Parkinson's Disease

    Condition:   Parkinson Disease
    Interventions:   Drug: N-acetylcysteine;   Drug: Placebo
    Sponsors:   Weill Medical College of Cornell University;   Weill Medical College of Cornell University;   National Institute on Aging (NIA)
    Recruiting - verified November 2011
  • A Biological Study of Resveratrol's Effects on Notch-1 Signaling in Subjects With Low Grade Gastrointestinal Tumors

    Condition:   Neuroendocrine Tumor
    Intervention:   Dietary Supplement: Resveratrol
    Sponsors:   University of Wisconsin, Madison;   University of Wisconsin, Madison
    Recruiting - verified February 2012
  • Chronic Fatigue Syndrome: A Presumptive Mitochondrial Disorder

    Condition:   Chronic Fatigue Syndrome
    Interventions:   Drug: Nutraceutical supplements;   Drug: Placebo
    Sponsors:   Columbia University;   Columbia University
    Not yet recruiting - verified November 2011
  • T-Cell Depleted Double UCB for Refractory AML

    Conditions:   Acute Myelogenous Leukemia;   Refractory Acute Myelogenous Leukemia
    Interventions:   Drug: Allopurinol;   Drug: Fludarabine;   Radiation: Total body irradiation;   Drug: Cyclophosphamide;   Drug: Levetiracetam;   Drug: Busulfan;   Biological: Umbilical Cord Blood Transplantation;   Biological: Interleukin-2
    Sponsors:   Masonic Cancer Center, University of Minnesota;   Masonic Cancer Center, University of Minnesota
    Recruiting - verified November 2011
  • Prevention of Serious Adverse Events Following Angiography

    Conditions:   Acute Renal Failure;   Kidney Disease;   Coronary Artery Disease
    Interventions:   Drug: IV isotonic saline;   Drug: IV isotonic bicarbonate;   Drug: N-acetylcysteine;   Drug: Placebo
    Sponsors:   Department of Veterans Affairs;   Department of Veterans Affairs;   The George Institute for Global Health
    Not yet recruiting - verified March 2012
  • Defined Green Tea Catechin Extract in Treating Patients With Plasma Cell Neoplasm Or Smoldering Multiple Myeloma

    Conditions:   Monoclonal Gammopathy of Undetermined Significance;   Smoldering Multiple Myeloma
    Interventions:   Dietary Supplement: defined green tea catechin extract;   Biological: laboratory biomarker analysis
    Sponsors:   Barbara Ann Karmanos Cancer Institute;   Barbara Ann Karmanos Cancer Institute;   National Cancer Institute (NCI)
    Recruiting - verified April 2012
  • Oral Nutrition Impact on Tear Film

    Condition:   Dry Eye Syndrome
    Intervention:   Dietary Supplement: Omega 3, Vitamins A, D3 and E
    Sponsors:   Eye and Vision Technologies and Research Institute;   Eye and Vision Technologies and Research Institute;   ZeaVision, Inc.
    Recruiting - verified March 2012
  • Effect of 6-week Strawberry Supplementation on Insulin Action (STR2)

    Conditions:   Insulin Resistance;   Nutritional Disease;   Metabolic Disease
    Interventions:   Dietary Supplement: Strawberry;   Dietary Supplement: Placebo1;   Dietary Supplement: Placebo2
    Sponsors:   Institute for Food Safety and Health, United States;   Institute for Food Safety and Health, United States;   California Strawberry Commission
    Recruiting - verified January 2012
  • Inhaled Nitric Oxide/INOpulse DS for Pulmonary Arterial Hypertension (PAH)

    Conditions:   Pulmonary Arterial Hypertension;   Pulmonary Hypertension
    Interventions:   Drug: Nitric Oxide;   Other: Placebo;   Drug: Nitric Oxide
    Sponsors:   INO Therapeutics;   INO Therapeutics
    Recruiting - verified May 2012
  • Study of the Safety and Efficacy of Long-Term Rilonacept Treatment for the Prevention of Gout Flares

    Condition:   Gout
    Interventions:   Drug: Rilonacept;   Drug: Placebo;   Drug: Allopurinol
    Sponsors:   Regeneron Pharmaceuticals;   Regeneron Pharmaceuticals
    Recruiting - verified January 2012
  • Safety and Neuroprotective Effects of Polyphenon E in MS; Phase II

    Condition:   Multiple Sclerosis
    Interventions:   Dietary Supplement: Polyphenon E;   Dietary Supplement: Placebo
    Sponsors:   National Center for Complementary and Alternative Medicine (NCCAM);   National Center for Complementary and Alternative Medicine (NCCAM)
    Recruiting - verified October 2011
  • Efficacy and Safety of Colchicine for the Prevention of Gout Flares During the Initiation of Allopurinol

    Condition:   Intercritical Gout
    Interventions:   Drug: Colchicine;   Drug: Placebo;   Drug: Allopurinol
    Sponsors:   Regeneron Pharmaceuticals;   Regeneron Pharmaceuticals
    Recruiting - verified April 2012
  • SPI-1005 for Prevention and Treatment of Chemotherapy Induced Hearing Loss

    Conditions:   Lung Cancer;   Head and Neck Cancer;   Hearing Loss;   Ototoxicity;   Tinnitus;   Neuropathy
    Interventions:   Drug: SPI-1005 Low Dose;   Drug: SPI-1005 Middle dose;   Drug: SPI-1005 High Dose;   Drug: Placebo
    Sponsors:   Sound Pharmaceuticals, Incorporated;   Sound Pharmaceuticals, Incorporated;   VA Puget Sound Health Care System
    Not yet recruiting - verified October 2011
  • Vitamin E δ-Tocotrienol Multiple Dose in Healthy Subjects

    Condition:   Pancreatic Cancer
    Intervention:   Drug: Vitamin E δ-Tocotrienol
    Sponsors:   H. Lee Moffitt Cancer Center and Research Institute;   H. Lee Moffitt Cancer Center and Research Institute;   National Cancer Institute (NCI);   BioGene Life Science
    Recruiting - verified March 2012
  • Otoprotection With SPI-1005

    Condition:   Temporary Auditory Threshold Shift
    Interventions:   Drug: SPI-1005 Low dose;   Drug: SPI-1005 Middle dose;   Drug: SPI-1005 High dose;   Drug: Placebo
    Sponsors:   Sound Pharmaceuticals, Incorporated;   Sound Pharmaceuticals, Incorporated;   University of Florida
    Recruiting - verified October 2011
  • Vitamin E δ-Tocotrienol (VEDT) Single Dose in Healthy Subjects

    Condition:   Pancreatic Cancer
    Intervention:   Drug: Vitamin E δ-Tocotrienol
    Sponsors:   H. Lee Moffitt Cancer Center and Research Institute;   H. Lee Moffitt Cancer Center and Research Institute;   National Cancer Institute (NCI);   BioGene Life Science
    Recruiting - verified March 2012
  • Q-Trial in Patients With Hepatitis C

    Condition:   Chronic Hepatitis C
    Intervention:   Dietary Supplement: Quercetin
    Sponsors:   University of California, Los Angeles;   University of California, Los Angeles;   American Association for Cancer Research;   Tower Cancer Research Foundation;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
    Recruiting - verified September 2011
  • Study to Evaluate Safety and Toxicity of Polyphenon E (EGCG) in HIV-1-Infected Individuals

    Condition:   HIV Infection
    Intervention:   Drug: Polyphenon E
    Sponsors:   Baylor College of Medicine;   Baylor College of Medicine;   National Center for Complementary and Alternative Medicine (NCCAM)
    Recruiting - verified September 2011
  • Intravenous N-acetylcysteine for the Treatment of Gaucher's Disease and Parkinson's Disease

    Conditions:   Parkinson's Disease;   Gaucher's Disease
    Intervention:   Drug: N-acetylcysteine
    Sponsors:   University of Minnesota - Clinical and Translational Science Institute;   University of Minnesota - Clinical and Translational Science Institute;   National Institute of Neurological Disorders and Stroke (NINDS);   Lysosomal Disease Network;   Rare Diseases Clinical Research Network
    Recruiting - verified April 2012
  • Evaluating N-Acetylcysteine in CTD-ILD Treatment

    Conditions:   Interstitial Lung Disease;   Connective Tissue Disease
    Intervention:   Drug: N-Acetylcysteine
    Sponsors:   University of Michigan;   University of Michigan
    Recruiting - verified December 2011
  • Vitamin E Supplementation in Burn Patients

    Condition:   Burn Injury
    Intervention:   Dietary Supplement: dl-alpha-tocopheryl acetate
    Sponsors:   Shriners Hospitals for Children;   Shriners Hospitals for Children;   University of Texas;   Oregon State University
    Recruiting - verified March 2012
  • Ascorbic Acid (Vitamin C) Infusion in Human Sepsis

    Conditions:   Sepsis;   Septic Shock;   Hypotension;   Acute Lung Injury
    Intervention:   Drug: Ascorbic Acid vs. Placebo
    Sponsors:   Virginia Commonwealth University;   Virginia Commonwealth University
    Recruiting - verified April 2012
  • Nitric Oxide Bioavailability in Chronic Obstructive Pulmonary Disease (COPD)

    Condition:   Pulmonary Disease, Chronic Obstructive
    Interventions:   Drug: Tetrahydrobiopterin (BH4);   Drug: non-acetylated salicylate;   Dietary Supplement: High Fat Meal;   Drug: L-NMMA;   Dietary Supplement: Antioxidant Cocktail
    Sponsors:   Georgia Health Sciences University;   Georgia Health Sciences University;   American Heart Association
    Recruiting - verified July 2011
  • Glutathione and Health With Post-Polio Syndrome

    Conditions:   Post-polio Syndrome;   Physical Activity;   Depression;   Pain;   Sleep Disorders
    Intervention:   Dietary Supplement: Glutathione
    Sponsors:   University of Michigan;   University of Michigan;   Penn State University
    Recruiting - verified March 2012
  • CoQ10 Biomarker Trial

    Conditions:   Oxidative Stress;   Inflammation;   Endothelial Dysfunction
    Interventions:   Dietary Supplement: Coenzyme Q10;   Dietary Supplement: Coenzyme Q10;   Dietary Supplement: Placebo
    Sponsors:   University of Washington;   University of Washington;   National Center for Complementary and Alternative Medicine (NCCAM)
    Recruiting - verified February 2012
  • Effect of the Anti-oxidant N-acetylcysteine on Beta-cell Function in Type 2 Diabetes

    Conditions:   Type 2 Diabetes;   Oxidative Stress
    Intervention:   Drug: N-acetylcysteine
    Sponsors:   Utzschneider, Kristina, M.D.;   Utzschneider, Kristina, M.D.;   VA Puget Sound Health Care System
    Recruiting - verified January 2012
  • Carotenoid Response to the Intake of Vegetables and Fruits

    Condition:   Resonance Raman Spectroscopy for Dietary Carotenoid Intake
    Interventions:   Other: Carotenoid Depletion;   Other: Carotenoid Repletion;   Other: Carotenoid Depletion;   Other: Natural Repletion
    Sponsors:   USDA Grand Forks Human Nutrition Research Center;   USDA Grand Forks Human Nutrition Research Center
    Recruiting - verified July 2011
  • Effects of Avocado When Added to a Meat Patty on Inflammation in Healthy Men

    Conditions:   To Demonstrate a Better Understanding of the Role of;   Bioactive Substances From Plant Foods Such as the;   Avocado May Demonstrate the Importance of Plant-based;   Antioxidants in Human Health
    Interventions:   Other: Avocado;   Other: No Avocado
    Sponsors:   University of California, Los Angeles;   University of California, Los Angeles
    Not yet recruiting - verified July 2011
  • Effects of N-acetylcysteine on Brain Chemistry and Behavior in Cocaine Abusers (NAC)

    Conditions:   Cocaine Abuse or Dependence;   Cocaine Related Disorders
    Intervention:  
    Sponsors:   Wayne State University;   Wayne State University
    Recruiting - verified October 2011
  • Phase II Evaluation of Exhaled Nitric Oxide (NO)

    Condition:   Lung Cancer
    Interventions:   Procedure: Nitric oxide breath test;   Behavioral: Questionnaires
    Sponsors:   M.D. Anderson Cancer Center;   M.D. Anderson Cancer Center;   National Institutes of Health (NIH)
    Recruiting - verified January 2012
  • Allopurinol Outcome Study

    Condition:   Gout
    Intervention:   Drug: Allopurinol
    Sponsors:   Ardea Biosciences, Inc.;   Ardea Biosciences, Inc.
    Recruiting - verified May 2012
  • Effects of Glutathione (an Antioxidant) and N-Acetylcysteine on Inflammation

    Conditions:   Obesity;   Hyperlipidemia;   Insulin Resistance;   Hypertension
    Interventions:   Dietary Supplement: Liposomal Glutathione Dietary Supplement;   Dietary Supplement: N-Acetyl cysteine Dietary Supplement;   Other: Placebo products for Glutathione and N-Acetylcysteine
    Sponsors:   Stanford University;   Stanford University
    Recruiting - verified March 2012
  • Safety Study of R(+)Pramipexole to Treat Early Alzheimer's Disease

    Condition:   Alzheimer's Disease
    Intervention:   Drug: R-pramipexole
    Sponsors:   Virginia Commonwealth University;   Virginia Commonwealth University;   University of Kansas;   Alzheimer’s Drug Discovery Foundation
    Recruiting - verified January 2012
  • Effect of Dietary Glycemic Index on Beta-cell Function

    Conditions:   Impaired Glucose Tolerance;   Oxidative Stress;   Prediabetes
    Interventions:   Other: low glycemic index diet;   Other: high glycemic index diet plus placebo;   Drug: high glycemic index diet plus N-acetylcysteine
    Sponsors:   Seattle Institute for Biomedical and Clinical Research;   Seattle Institute for Biomedical and Clinical Research;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   VA Puget Sound Health Care System
    Recruiting - verified January 2012
  • Modulation of Cerebral Blood Flow Using Quercetin, a Nutritional Supplement

    Conditions:   Stroke;   Problem of Aging
    Intervention:   Dietary Supplement: quercetin/placebo
    Sponsors:   Brigham and Women's Hospital;   Brigham and Women's Hospital;   National Institute on Aging (NIA)
    Recruiting - verified June 2011
  • The Effects of Vitamin E and Vitamin C and Exercise

    Condition:   Exercise and Non-exercise Effect Upon Vitamins E and C
    Interventions:   Dietary Supplement: Vitamin E and Vitamin C;   Drug: placeboes
    Sponsors:   USDA Grand Forks Human Nutrition Research Center;   USDA Grand Forks Human Nutrition Research Center
    Recruiting - verified July 2011
  • The Effect of Sodium Thiosulfate Eardrops on Hearing Loss in Patients Who Receive Cisplatin Therapy

    Condition:   Cancer
    Interventions:   Procedure: Insertion of Pressure Equalization (PE) Tubes;   Drug: Sodium Thiosulfate (STS);   Other: Saline (Placebo);   Drug: Cisplatin
    Sponsors:   Thomas Jefferson University;   Thomas Jefferson University
    Recruiting - verified January 2012
  • Nutritional Intervention in Children With Autism Using Whey Protein (Immunocal): Impact on Core Areas of Behavior

    Condition:   Autism Spectrum Disorders
    Interventions:   Dietary Supplement: Whey Protein;   Dietary Supplement: Rice Protein (Placebo)
    Sponsors:   Nova Southeastern University;   Nova Southeastern University;   Immunotec Inc.
    Recruiting - verified June 2011
  • New Treatment Option for Pancreatic Cancer

    Condition:   Pancreatic Cancer
    Intervention:   Drug: Vitamin C
    Sponsors:   University of Kansas;   Jeanne Drisko, MD, CNS, FACN;   Lotte and John Hecht Memorial Foundation;   University of Kansas
    Recruiting - verified September 2011
  • Pilot Study of Resveratrol in Older Adults With Impaired Glucose Tolerance

    Condition:   Impaired Glucose Tolerance
    Interventions:   Dietary Supplement: resveratrol;   Drug: Placebo
    Sponsors:   Albert Einstein College of Medicine of Yeshiva University;   Albert Einstein College of Medicine of Yeshiva University;   American Diabetes Association
    Recruiting - verified June 2011
  • The Effect of N-Acetyl Cysteine on Cortical Erosion in Early Stage Schizophrenia

    Conditions:   Schizophrenia;   Psychotic Disorder NOS;   Schizoaffective Disorder;   Schizophreniform
    Interventions:   Drug: N-Acetyl Cysteine;   Other: sugar pill
    Sponsors:   Indiana University;   Indiana University;   Stanley Medical Research Institute;   Indiana University School of Medicine;   The Brain Research Foundation
    Recruiting - verified April 2012
  • Topical MTS-01 for Dermatitis During Radiation and Chemotherapy for Anal Cancer

    Condition:   Anal Cancer
    Interventions:   Drug: Tempol;   Drug: 5-Fluorouracil;   Drug: Mitomycin-C;   Procedure: Radiation Therapy
    Sponsors:   National Institutes of Health Clinical Center (CC);   National Cancer Institute (NCI)
    Recruiting - verified November 2011
  • The Relationship Between Uric Acid and Inflammatory Markers

    Condition:   Healthy Volunteers
    Interventions:   Drug: IV Uric Acid;   Drug: IV Rasburicase
    Sponsors:   National Institutes of Health Clinical Center (CC);   National Institute on Aging (NIA)
    Recruiting - verified August 2010
  • Study of Vitamin D and Uric Acid Lowering on Kidney and Blood Vessel Function

    Conditions:   Renal Function;   Endothelial Function;   Blood Pressure;   Overweight;   Obesity
    Interventions:   Drug: Vitamin D ergocalciferol;   Drug: Probenecid;   Drug: Allopurinol;   Drug: Placebo;   Drug: Placebo
    Sponsors:   Brigham and Women's Hospital;   Brigham and Women's Hospital;   National Heart, Lung, and Blood Institute (NHLBI)
    Recruiting - verified January 2012
  • Alpha-lipoic Acid in Patients at Risk for Paclitaxel Induced Neuropathy

    Condition:   Peripheral Neuropathy
    Intervention:   Dietary Supplement: Alpha lipoic acid
    Sponsors:   Northwestern University;   Northwestern University
    Not yet recruiting - verified June 2011
  • Effect of Early Limited Formula on Total Serum Bilirubin Among Newborns With Hyperbilirubinemia

    Condition:   Hyperbilirubinemia, Neonatal
    Intervention:   Dietary Supplement: Nutramigen Infant Formula
    Sponsors:   University of California, San Francisco;   University of California, San Francisco
    Not yet recruiting - verified March 2012
  • Study in Subjects With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension (PH) Secondary to Idiopathic Pulmonary Fibrosis (IPF) Using Inhaled NITROsyl

    Conditions:   Pulmonary Arterial Hypertension (PAH);   Pulmonary Hypertension-Idiopathic Pulmonary Fibrosis (PH-IPF)
    Interventions:   Drug: Inhaled Nitric Oxide;   Drug: Inhaled Nitric Oxide;   Drug: Inhaled Nitric Oxide;   Drug: Inhaled Nitric Oxide;   Drug: Inhaled Nitric Oxide
    Sponsors:   Geno LLC;   Geno LLC
    Recruiting - verified April 2012
  • Glutathione in Diabetic Nephropathy

    Conditions:   Diabetic Nephropathy;   Proteinuria;   Oxidative Stress
    Interventions:   Drug: N-acetylcysteine placebo + silibin placebo;   Drug: N-acetylcysteine active + silibin placebo;   Drug: N-acetylcysteine placebo + silibin active;   Drug: N-acetylcysteine active + silibin active;   Drug: N-acetylcysteine active + high-dose silibin active
    Sponsors:   Department of Veterans Affairs;   Department of Veterans Affairs
    Recruiting - verified April 2012
  • Pentoxifylline for Primary Biliary Cirrhosis

    Condition:   Primary Biliary Cirrhosis
    Intervention:   Drug: Pentoxifylline
    Sponsors:   The Cleveland Clinic;   The Cleveland Clinic
    Recruiting - verified June 2011
  • The Effect of Avocado on Cardiovascular Disease (CVD) Risk Factors

    Condition:   Cardiovascular Disease
    Interventions:   Other: Avocado Diet;   Other: Lower-Fat Diet;   Other: Moderate Fat Diet
    Sponsors:   Penn State University;   Penn State University;   Hass Avocado Board
    Recruiting - verified July 2011
  • Pentoxifylline Treatment of Acute Pancreatitis

    Condition:   Acute Pancreatitis
    Interventions:   Drug: study medication;   Drug: sugar pill
    Sponsors:   Mayo Clinic;   Mayo Clinic
    Recruiting - verified January 2012
  • Cranberry Proanthocyanidins for Modification of Intestinal E. Coli Flora and Prevention of Urinary Tract Infections in UTI-Susceptible Women

    Condition:   Urinary Tract Infection
    Interventions:   Other: Sweetened, dried cranberries;   Other: Strawberry Fruit Pieces;   Other: Sweetened, dried cranberries;   Other: Sweetened, dried cranberries;   Other: Strawberry Fruit Pieces;   Other: No treatment
    Sponsors:   University of Wisconsin, Madison;   University of Wisconsin, Madison;   Ocean Spray Cranberries, Inc.
    Recruiting - verified November 2011
  • Inhaled Nitric Oxide (iNO) as an Adjunct to Neonatal Resuscitation

    Conditions:   Prematurity;   Low Birth Weight
    Interventions:   Drug: Inhaled Nitric Oxide;   Other: Nitrogen
    Sponsors:   University of Oklahoma;   Kris Sekar;   Ikaria Holdings Inc.
    Recruiting - verified April 2012
  • N-acetylcysteine Plus Naltrexone for the Treatment of Alcohol Dependence

    Condition:   Alcoholism
    Interventions:   Drug: N-acetylcysteine + high-dose naltrexone (150 mg);   Drug: High-dose naltrexone (150 mg) alone;   Drug: Low-dose naltrexone (50 mg) alone
    Sponsors:   Department of Veterans Affairs;   Department of Veterans Affairs
    Recruiting - verified March 2012
  • Selenium in the Treatment of Complicated Lymphatic Malformations

    Condition:   Lymphatic Malformations
    Intervention:   Drug: Selenium
    Sponsors:   Medical College of Wisconsin;   Medical College of Wisconsin
    Recruiting - verified June 2011
  • Rasburicase in Patients at High Risk for Tumor Lysis Syndrome (TLS) During Cycle-2

    Conditions:   Leukemia;   Lymphoma
    Interventions:   Drug: Rasburicase;   Drug: Allopurinol
    Sponsors:   M.D. Anderson Cancer Center;   M.D. Anderson Cancer Center;   Sanofi-Aventis
    Recruiting - verified April 2012
  • Lipoic Acid for Secondary Progressive Multiple Sclerosis (MS)

    Condition:   Multiple Sclerosis, Chronic Progressive
    Interventions:   Drug: lipoic acid;   Drug: Placebo
    Sponsors:   Department of Veterans Affairs;   Department of Veterans Affairs;   Oregon Health and Science University
    Recruiting - verified March 2012
  • Local Vasoconstriction in Postural Tachycardia Syndrome

    Condition:   Postural Tachycardia Syndrome
    Interventions:   Drug: Losartan;   Drug: Ascorbic Acid (Vitamin C);   Drug: Normal Saline
    Sponsors:   New York Medical College;   New York Medical College
    Recruiting - verified December 2011
  • Oxidative Stress Links Aging, Activity and Mobility Limitation

    Condition:   Aging
    Intervention:   Dietary Supplement: Vitamins C, E, and alpha lipoic acid
    Sponsors:   Department of Veterans Affairs;   Department of Veterans Affairs;   University of Utah
    Not yet recruiting - verified January 2012
  • Effect of Zonisamide on Cocaine Reinforcement, Craving, and Relapse

    Condition:   Cocaine Dependence
    Interventions:   Drug: Zonisamide;   Drug: Placebo;   Drug: Cocaine Hydrochloride;   Behavioral: Neurocognitive and Performance Battery;   Behavioral: Smoking Assessments
    Sponsors:   Johns Hopkins University;   Johns Hopkins University;   National Institute on Drug Abuse (NIDA)
    Recruiting - verified June 2011
  • Autonomic Nervous System and Nitric Oxide Interactions

    Condition:   Endothelial Dysfunction
    Interventions:   Drug: Trimethaphan;   Drug: Placebo
    Sponsors:   Vanderbilt University;   Vanderbilt University
    Recruiting - verified April 2012
  • Safety and Efficacy Study of a New Formulation of Acetylcysteine Injection

    Condition:   Acetaminophen Overdose
    Interventions:   Drug: Acetadote EF;   Drug: Acetadote
    Sponsors:   Cumberland Pharmaceuticals;   Cumberland Pharmaceuticals
    Recruiting - verified May 2012
  • Influence of Selenium on Biomarkers of Prostate Cancer Risk

    Condition:   Prostate Cancer
    Interventions:   Other: Placebo;   Drug: SM;   Drug: Third Group;   Drug: Fourth Group
    Sponsors:   Penn State University;   Penn State University
    Recruiting - verified July 2011
  • Siliphos in Advanced Hepatocellular Carcinoma

    Condition:   Advanced Hepatocellular Carcinoma
    Intervention:   Drug: Silybin
    Sponsors:   Columbia University;   Columbia University;   Lotte and John Hecht Memorial Foundation
    Recruiting - verified October 2011
  • Cardiovascular Safety of Febuxostat and Allopurinol in Patients With Gout and Cardiovascular Comorbidities

    Condition:   Cardiovascular Disease
    Interventions:   Drug: Febuxostat;   Drug: Allopurinol
    Sponsors:   Takeda Global Research & Development Center, Inc.;   Takeda Global Research & Development Center, Inc.
    Recruiting - verified February 2012
  • Imaging the Nucleus Accumbens in Major Depressed Patients 'Treated With Pramipexole

    Condition:   Depression
    Intervention:   Drug: Pramipexole
    Sponsors:   Stanford University;   Stanford University
    Recruiting - verified August 2010
  • N-Acetyl Cysteine in Pathologic Skin Picking

    Conditions:   Pathologic Skin Picking;   Neurotic Excoriation;   Psychogenic Excoriation;   Dermatillomania
    Interventions:   Drug: N-Acetyl Cysteine;   Drug: Placebo
    Sponsors:   University of Minnesota - Clinical and Translational Science Institute;   University of Minnesota - Clinical and Translational Science Institute
    Recruiting - verified March 2012
  • Antioxidant Therapy to Reduce Inflammation in Sickle Cell Disease

    Condition:   Anemia, Sickle Cell
    Intervention:   Drug: alpha-lipoic acid and acetyl-L-carnitine
    Sponsors:   Children's Hospital & Research Center Oakland;   Children's Hospital & Research Center Oakland;   National Center for Complementary and Alternative Medicine (NCCAM)
    Recruiting - verified August 2011
  • Role of Skeletal Muscle Nitric Oxide Production in Age-related Fatigue and Fatigability

    Conditions:   Fatigue;   Aging
    Interventions:   Drug: Sildenafil placebo;   Drug: Sildenafil
    Sponsors:   The University of Texas, Galveston;   The University of Texas, Galveston
    Recruiting - verified July 2011
  • Lipoic Acid and Omega-3 Fatty Acids for Alzheimer's Disease

    Condition:   Alzheimer's Disease
    Intervention:   Drug: lipoic acid and fish oil concentrate
    Sponsors:   Oregon Health and Science University;   Oregon Health and Science University
    Recruiting - verified May 2012
  • Nebivolol in the Supine Hypertension of Autonomic Failure

    Conditions:   Hypertension;   Pure Autonomic Failure;   Multiple System Atrophy
    Interventions:   Drug: Placebo;   Drug: Nebivolol 5 mg;   Drug: metoprolol tartrate 50 mg;   Drug: Sildenafil25 mg
    Sponsors:   Vanderbilt University;   Vanderbilt University;   Forest Laboratories
    Recruiting - verified May 2012
  • Obesity, Inflammation and Oxidative Stress

    Conditions:   C-reactive Protein;   Inflammation;   Obesity;   Oxidative Stress
    Intervention:   Dietary Supplement: Vitamin C (ascorbic acid)
    Sponsors:   University of California, Berkeley;   University of California, Berkeley;   Kaiser Permanente
    Recruiting - verified June 2011
  • Phase III Study of Idebenone in Duchenne Muscular Dystrophy (DMD)

    Conditions:   Muscular Dystrophy, Duchenne;   Ambulatory Care
    Intervention:   Drug: Idebenone (CATENA®)
    Sponsors:   Santhera Pharmaceuticals;   Santhera Pharmaceuticals
    Recruiting - verified March 2012
  • Safety, Metabolism, and Antioxidant Activity of Silymarin and Green Tea Extract in Patients With Chronic Hepatitis C

    Conditions:   Chronic Hepatitis C;   Oxidative Stress
    Interventions:   Dietary Supplement: silymarin;   Dietary Supplement: green tea extract (EGCG)
    Sponsors:   University of North Carolina, Chapel Hill;   University of North Carolina, Chapel Hill;   National Center for Complementary and Alternative Medicine (NCCAM);   National Institutes of Health (NIH)
    Recruiting - verified November 2011
  • Trial of Late Surfactant for Prevention of Bronchopulmonary Dysplasia

    Condition:   Bronchopulmonary Dysplasia
    Intervention:   Drug: Infasurf surfactant (ONY, Inc.)
    Sponsors:   University of California, San Francisco;   University of California, San Francisco;   National Heart, Lung, and Blood Institute (NHLBI)
    Recruiting - verified January 2012
  • Study of Oral Arsenic Trioxide With or Without Ascorbic Acid in Adults With Myelofibrosis

    Condition:   Primary Myelofibrosis
    Intervention:   Drug: Dose Escalating Arsenic Trioxide plus ascorbic Acid
    Sponsors:   Roswell Park Cancer Institute;   Roswell Park Cancer Institute;   Cephalon
    Recruiting - verified February 2012
  • Prevalence of Non-alcoholic Fatty Liver Disease (NAFLD) in Hispanics With Diabetes Mellitus Type 2 (T2DM) and Role of Treatment

    Condition:   Nonalcoholic Steatohepatitis
    Interventions:   Drug: placebo;   Drug: pioglitazone;   Dietary Supplement: Vitamin E
    Sponsors:   Department of Veterans Affairs;   Department of Veterans Affairs
    Recruiting - verified February 2012
  • Defining the Anti-inflammatory Role of Lipoic Acid in Multiple Sclerosis

    Condition:   Multiple Sclerosis
    Intervention:   Dietary Supplement: Lipoic Acid
    Sponsors:   Portland VA Medical Center;   Portland VA Medical Center;   Oregon Health and Science University
    Recruiting - verified January 2012
  • Ischemia/Reperfusion Injury of Human Endothelium: Role of Glucose and Statins

    Condition:   Hyperglycemia
    Interventions:   Drug: 5% dextrose;   Drug: vitamin C;   Drug: Simvastatin;   Drug: L-NMMA
    Sponsors:   Department of Veterans Affairs;   Department of Veterans Affairs
    Recruiting - verified May 2012
  • Using Allopurinol to Relieve Symptoms in Patients With Heart Failure and High Uric Acid Levels

    Conditions:   Heart Failure;   Elevated Serum Uric Acid
    Interventions:   Drug: allopurinol;   Drug: sugar pill
    Sponsors:   Duke University;   Duke University;   National Heart, Lung, and Blood Institute (NHLBI)
    Recruiting - verified April 2012
  • Vitamin E δ-Tocotrienol Administered to Subjects With Resectable Pancreatic Exocrine Neoplasia

    Condition:   Pancreatic Neoplasms
    Intervention:   Drug: Vitamin E δ-Tocotrienol
    Sponsors:   H. Lee Moffitt Cancer Center and Research Institute;   H. Lee Moffitt Cancer Center and Research Institute;   National Cancer Institute (NCI)
    Recruiting - verified January 2012
  • Melphalan, Carboplatin, and Sodium Thiosulfate for Patients With Central Nervous System (CNS) Embryonal or Germ Cell Tumors

    Conditions:   Central Nervous System Embryonal Tumor;   Germ Cell Tumors
    Interventions:   Drug: Melphalan;   Drug: Carboplatin;   Drug: Sodium thiosulfate;   Drug: Filgrastim;   Drug: Pegfilgrastim
    Sponsors:   OHSU Knight Cancer Institute;   OHSU Knight Cancer Institute
    Recruiting - verified January 2012
  • Inhaled Iloprost as an Adjunct to Inhaled Nitric Oxide in Pediatric Critical Care Patients

    Conditions:   Pulmonary Hypertension;   Neonatal Hypoxic Respiratory Failure;   Persistent Pulmonary Hypertension of Newborn;   Congenital Heart Defects;   Acute Respiratory Distress Syndrome
    Interventions:   Drug: Iloprost;   Drug: Placebo
    Sponsors:   Seattle Children's Hospital;   Seattle Children's Hospital;   Actelion
    Recruiting - verified July 2011
  • The Effect of Grape Seed Extract on Blood Pressure in People With Pre-Hypertension

    Condition:   Hypertension
    Interventions:   Dietary Supplement: grape seed extract;   Dietary Supplement: grape seed extract placebo
    Sponsors:   Institute for Food Safety and Health, United States;   Institute for Food Safety and Health, United States;   Polyphenolics, Inc.
    Recruiting - verified January 2012
  • Trial of Curcumin in Cutaneous T-cell Lymphoma Patients

    Condition:   Cutaneous T-cell Lymphoma
    Interventions:   Drug: Curcumin (Turmeric);   Behavioral: Questionnaires;   Other: Photos
    Sponsors:   M.D. Anderson Cancer Center;   M.D. Anderson Cancer Center
    Not yet recruiting - verified May 2012
  • Pilot Study of Melatonin and Refractory Epilepsy

    Condition:   Epilepsy
    Intervention:   Drug: Melatonin
    Sponsors:   Children's Hospital Medical Center, Cincinnati;   Children's Hospital Medical Center, Cincinnati
    Recruiting - verified January 2012
  • Lipoic Acid to Treat Chronic Inflammatory Demyelinating Polyneuropathy

    Conditions:   CIDP;   Chronic Inflammatory Demyelinating Polyneuropathy
    Intervention:   Drug: lipoic acid
    Sponsors:   Oregon Health and Science University;   Oregon Health and Science University;   Collins Medical Trust
    Recruiting - verified February 2012
  • Examining the Use of Non-Invasive Inhaled Nitric Oxide to Reduce Chronic Lung Disease in Premature Newborns

    Condition:   Bronchopulmonary Dysplasia
    Interventions:   Drug: Inhaled Nitric Oxide (iNO);   Drug: Nitrogen (placebo)
    Sponsors:   National Heart, Lung, and Blood Institute (NHLBI);   National Heart, Lung, and Blood Institute (NHLBI)
    Recruiting - verified May 2012
  • Double Blind Placebo-Controlled Phase I/II Clinical Trial of Idebenone in Patients With Primary Progressive Multiple Sclerosis (IPPoMS)

    Condition:   Primary Progressive Multiple Sclerosis
    Intervention:   Drug: Idebenone
    Sponsors:   National Institutes of Health Clinical Center (CC);   National Institute of Neurological Disorders and Stroke (NINDS)
    Recruiting - verified January 2012
  • Melatonin Treatment for Induced Transient Insomnia

    Conditions:   Delayed Sleep Phase Disorder;   Jet-lag;   Shift-work Disorder
    Interventions:   Dietary Supplement: Melatonin;   Dietary Supplement: Placebo
    Sponsors:   Brigham and Women's Hospital;   Brigham and Women's Hospital
    Recruiting - verified June 2011
  • Green Tea Extract in Treating Patients With Monoclonal Gammopathy of Undetermined Significance and/or Smoldering Multiple Myeloma

    Conditions:   Multiple Myeloma and Plasma Cell Neoplasm;   Precancerous Condition
    Interventions:   Dietary Supplement: defined green tea catechin extract;   Genetic: gene expression analysis;   Genetic: protein analysis;   Other: laboratory biomarker analysis
    Sponsors:   Barbara Ann Karmanos Cancer Institute;   Barbara Ann Karmanos Cancer Institute;   National Cancer Institute (NCI)
    Recruiting - verified November 2011
  • Green Tea and Reduction of Breast Cancer Risk

    Condition:   Breast Cancer
    Interventions:   Drug: Green tea extract supplement;   Other: Placebo
    Sponsors:   University of Minnesota - Clinical and Translational Science Institute;   University of Minnesota - Clinical and Translational Science Institute
    Recruiting - verified January 2012
  • N-Acetylcysteine and Milk Thistle for Treatment of Diabetic Nephropathy

    Conditions:   Diabetic Nephropathies;   Proteinuria;   Oxidative Stress
    Interventions:   Dietary Supplement: N-acetylcysteine;   Dietary Supplement: silibin;   Dietary Supplement: high-dose silibin;   Dietary Supplement: N-acetylcysteine placebo;   Dietary Supplement: silibin placebo
    Sponsors:   The University of Texas Health Science Center at San Antonio;   The University of Texas Health Science Center at San Antonio;   National Center for Complementary and Alternative Medicine (NCCAM);   Department of Veterans Affairs
    Recruiting - verified August 2011
  • Intravenous Milk Thistle (Silibinin-Legalon) for Hepatic Failure Induced by Amatoxin/Amanita Mushroom Poisoning

    Conditions:   Amatoxin Poisoning;   Amanita Poisoning;   Mushroom Poisoning;   Liver Failure
    Intervention:   Drug: Legalon SIL (Silibinin)
    Sponsors:   Madaus Inc;   Madaus Inc
    Recruiting - verified June 2011
  • Vitamin E Supplements in Treating Patients Undergoing Surgery for Colorectal Cancer

    Condition:   Colorectal Cancer
    Interventions:   Dietary Supplement: vitamin E;   Other: laboratory biomarker analysis
    Sponsors:   University of Medicine and Dentistry New Jersey;   University of Medicine and Dentistry New Jersey;   National Cancer Institute (NCI)
    Recruiting - verified October 2011
  • Nonmyeloablative Stem Cell Transplantation for Chronic Lymphocytic Leukemia (CLL)

    Condition:   Chronic Lymphocytic Leukemia
    Interventions:   Drug: Lenalidomide;   Drug: Fludarabine;   Drug: Rituximab;   Drug: Thymoglobulin;   Procedure: Stem Cell Transplantation;   Drug: Bendamustine;   Drug: Allopurinol
    Sponsors:   M.D. Anderson Cancer Center;   M.D. Anderson Cancer Center;   Celgene Corporation
    Recruiting - verified May 2012
  • Melatonin for Circadian Sleep Disorders in the Blind

    Conditions:   Insomnia;   Blindness;   Daytime Sleepiness
    Interventions:   Drug: Melatonin;   Behavioral: Regular Sleep Schedule;   Behavioral: Light
    Sponsors:   Oregon Health and Science University;   Oregon Health and Science University
    Recruiting - verified July 2011
  • Vitamin E Supplements in Preventing Cancer in Patients at Risk of Prostate Cancer or Who Have Prostate Cancer

    Condition:   Prostate Cancer
    Interventions:   Dietary Supplement: vitamin E;   Procedure: sham intervention
    Sponsors:   University of Medicine and Dentistry New Jersey;   University of Medicine and Dentistry New Jersey;   National Cancer Institute (NCI)
    Recruiting - verified December 2011
  • Study of Glutathione, Vitamin C and Cysteine in Children With Autism and Severe Behavior Problems

    Conditions:   Autism;   Severe Behavior Disorder
    Interventions:   Drug: placebo;   Drug: glutathione;   Drug: glutathione, vitamin C and N-acetylcysteine
    Sponsors:   University of Louisville;   University of Louisville;   Kosair Children's Hospital Foundation;   Cumberland Pharmaceuticals
    Recruiting - verified September 2011
  • Study of Idebenone in the Treatment of Mitochondrial Encephalopathy Lactic Acidosis & Stroke-like Episodes

    Condition:   MELAS Syndrome
    Interventions:   Drug: Idebenone;   Drug: Idebenone;   Other: Placebo
    Sponsors:   Columbia University;   Columbia University;   Santhera Pharmaceuticals
    Recruiting - verified February 2012
  • Skin and Serum Carotenoids in Preterm Infants Fed on a Formula Supplemented With Carotenoids

    Condition:   Retinopathy of Prematurity
    Intervention:   Dietary Supplement: carotenoids
    Sponsors:   University of Utah;   University of Utah;   Abbott
    Recruiting - verified April 2012
  • PMRR-NO: Pulmonary Metabolic Radiation Response Versus Exhaled Nitric Oxide

    Conditions:   Gastrointestinal Disease;   Esophageal Cancer;   Lung Cancer
    Interventions:   Procedure: Breathing Test;   Behavioral: Respiratory Symptoms Questionnaire;   Procedure: Pet Scan
    Sponsors:   M.D. Anderson Cancer Center;   M.D. Anderson Cancer Center
    Recruiting - verified March 2012
  • Respiratory and Autonomic Plasticity Following Intermittent Hypoxia

    Condition:   Sleep Apnea Syndromes
    Intervention:   Dietary Supplement: Antioxidant cocktail
    Sponsors:   Department of Veterans Affairs;   Department of Veterans Affairs
    Recruiting - verified September 2011
  • Vitamin E Pharmacokinetics and Biomarkers in Normal and Obese Women

    Condition:   Diabetes Mellitus Type II Non Insulin Dependent
    Interventions:   Dietary Supplement: Vitamin E;   Dietary Supplement: Vitamin C;   Dietary Supplement: Lipid Oxidation
    Sponsors:   National Institutes of Health Clinical Center (CC);   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
    Not yet recruiting - verified August 2011
  • Interdisciplinary Study of Two Novel Anticonvulsants in Alcoholism

    Conditions:   Alcoholism;   Alcohol Dependence;   Alcohol Abuse
    Interventions:   Drug: topiramate;   Drug: zonisamide;   Drug: Levetiracetam;   Drug: Placebo
    Sponsors:   Boston Medical Center;   Boston Medical Center;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting - verified May 2011
  • The Effect of Selenium Supplementation Among Pediatric Patients With Burns

    Condition:   Burns
    Interventions:   Drug: IV selenium;   Drug: IV selenium;   Drug: Saline
    Sponsors:   Shriners Hospitals for Children;   Shriners Hospitals for Children
    Recruiting - verified March 2012
  • Quantitative in Vivo Biomarkers of Oxidative Stress in Diabetes

    Conditions:   Type 2 Diabetes;   Oxidative Stress
    Intervention:   Biological: ascorbic acid (Vitamin C)
    Sponsors:   University of Kansas;   University of Kansas
    Recruiting - verified July 2011
  • Melatonin Studies of Totally Blind Children

    Conditions:   Sleep Disorder;   Blindness
    Intervention:   Drug: Melatonin
    Sponsors:   Oregon Health and Science University;   Oregon Health and Science University
    Recruiting - verified July 2011
  • Impact of Maternal Pomegranate Juice on Brain Injury in Infants With Intrauterine Growth Restriction (IUGR)

    Condition:   Intrauterine Growth Restriction
    Interventions:   Dietary Supplement: Pomegranate Juice;   Dietary Supplement: Placebo
    Sponsors:   Washington University School of Medicine;   Washington University School of Medicine;   University of California, Los Angeles
    Recruiting - verified August 2011
  • Treatment of Systemic Lupus Erythematosus (SLE) With N-acetylcysteine

    Condition:   Systemic Lupus Erythematosus
    Interventions:   Drug: N-acetylcysteine;   Drug: N-acetylcysteine;   Drug: Placebo
    Sponsors:   State University of New York - Upstate Medical University;   State University of New York - Upstate Medical University
    Recruiting - verified January 2012
  • Lipoic Acid and Prevention of Heart Disease

    Condition:   Atherosclerosis
    Interventions:   Dietary Supplement: R-alpha lipoic acid;   Dietary Supplement: Placebo
    Sponsors:   Oregon State University;   Oregon State University;   Oregon Health and Science University;   National Center for Complementary and Alternative Medicine (NCCAM)
    Recruiting - verified February 2012
  • The Role of R-Alpha Lipoic Acid in the Treatment of Atherosclerotic Vascular Disease

    Condition:   Atherosclerosis
    Intervention:   Dietary Supplement: Crossover of R-alpha lipoic acid and placebo
    Sponsors:   Oregon State University;   Oregon State University;   Oregon Health and Science University;   National Center for Complementary and Alternative Medicine (NCCAM)
    Recruiting - verified February 2012
  • Selenomethionine and Finasteride Before Surgery or Radiation Therapy in Treating Patients With Stage I or Stage II Prostate Cancer

    Condition:   Prostate Cancer
    Interventions:   Dietary Supplement: selenomethionine;   Drug: finasteride;   Other: placebo
    Sponsors:   Roswell Park Cancer Institute;   Roswell Park Cancer Institute
    Recruiting - verified May 2012
  • Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy

    Conditions:   Brain and Central Nervous System Tumors;   Childhood Germ Cell Tumor;   Extragonadal Germ Cell Tumor;   Liver Cancer;   Neuroblastoma;   Ototoxicity;   Ovarian Cancer;   Sarcoma
    Interventions:   Drug: sodium thiosulfate;   Procedure: examination
    Sponsors:   National Cancer Institute (NCI);   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified May 2012
  • Efficacy of Natural Vitamin E Tocotrienol on the Treatment of Surgical Scars

    Condition:   Scar
    Interventions:   Dietary Supplement: Natural Vitamin E Tocotrienol (TCT);   Dietary Supplement: Natural Vitamin E Tocotrienol (TCT);   Other: Placebo;   Other: Placebo Cream
    Sponsors:   Ohio State University;   Chandan Sen
    Recruiting - verified March 2012
  • Blind Child Melatonin Treatment Study

    Condition:   Blindness
    Interventions:   Dietary Supplement: Melatonin;   Dietary Supplement: Melatonin;   Dietary Supplement: Melatonin
    Sponsors:   Oregon Health and Science University;   Oregon Health and Science University;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
    Recruiting - verified June 2011
  • Bioavailability of Golden Rice Carotenoids in Humans

    Condition:   Healthy
    Intervention:   Dietary Supplement: golden rice
    Sponsors:   Tufts University;   Tufts University
    Recruiting - verified April 2012
  • Phase II Trial of Silymarin for Non-Cirrhotic Patients With Non-Alcoholic Steatohepatitis

    Condition:   Non-cirrhotic Non-alcoholic Steatohepatitis
    Interventions:   Other: Placebo;   Drug: Silymarin;   Drug: Silymarin
    Sponsors:   Madaus Inc;   Madaus Inc;   University of Pennsylvania;   University of North Carolina;   Thomas Jefferson University;   Beth Israel Deaconess Medical Center;   Brooke Army Medical Center;   University of Pittsburgh
    Recruiting - verified June 2011
  • Human Tissue Distribution of Orally Supplemented Natural Vitamin E Tocotrienol

    Conditions:   End Stage Cardiac Failure;   Pulmonary Failure;   End Stage Liver Disease;   Morbid Obesity;   Recalcitrant Epilepsy Requiring Surgery;   Healthy Subjects
    Interventions:   Dietary Supplement: To surgery patients, Tocotrienol or Tocopherol capsules.;   Dietary Supplement: Tocotrienol or Tocopherol to healthy subjects.
    Sponsors:   Ohio State University;   Ohio State University
    Recruiting - verified August 2011
  • Evaluating the Effectiveness of Prednisone, Azathioprine, and N-acetylcysteine in People With Idiopathic Pulmonary Fibrosis

    Condition:   Pulmonary Fibrosis
    Interventions:   Drug: N-acetylcysteine (NAC);   Drug: Placebo
    Sponsors:   National Heart, Lung, and Blood Institute (NHLBI);   National Heart, Lung, and Blood Institute (NHLBI)
    Recruiting - verified January 2012
  • Safety Study Of N-Acetylcysteine For Prevention Of Contrast Induced Nephropathy In Patients w/Stage 3 Renal Failure

    Condition:   Contrast Induced Nephropathy
    Intervention:   Drug: N-acetylcysteine
    Sponsors:   Oregon Health and Science University;   Oregon Health and Science University
    Recruiting - verified July 2011
  • Treating Oxidative Stress and the Metabolic Pathology of Autism

    Condition:   Autistic Disorder
    Interventions:   Dietary Supplement: B12;   Dietary Supplement: Placebo;   Dietary Supplement: folate;   Dietary Supplement: B complex;   Dietary Supplement: vitamin C;   Dietary Supplement: cod liver oil;   Dietary Supplement: Mineral complex;   Dietary Supplement: carnitine
    Sponsors:   Arkansas Children's Hospital Research Institute;   Arkansas Children's Hospital Research Institute
    Recruiting - verified January 2012
  • Evaluation of the Wear of Vitamin E Treated Polyethylene Components in Primary THA Using RSA

    Conditions:   Osteoarthritis of Hip;   Traumatic Arthritis of Hip
    Intervention:   Procedure: Hip replacement
    Sponsors:   Massachusetts General Hospital;   Massachusetts General Hospital;   Biomet, Inc.
    Recruiting - verified June 2011
  • Melatonin Metabolism Abnormality in Patients With Schizophrenia or Schizoaffective Disorder Treated With Olanzapine

    Conditions:   Schizophrenia;   Schizoaffective Disorder;   Bipolar Disorder;   Obesity;   Metabolic Syndrome
    Intervention:   Drug: olanzapine and melatonin
    Sponsors:   Seattle Institute for Biomedical and Clinical Research;   Seattle Institute for Biomedical and Clinical Research;   Eli Lilly and Company
    Recruiting - verified November 2011
  • Treatment Strategies for Children With Smith-Magenis Syndrome

    Conditions:   Developmental Delay Disorders;   Chromosome Deletion;   Mental Retardation;   Sleep Disorders, Circadian Rhythm;   Self Injurious Behavior
    Interventions:   Drug: dTR Melatonin (NIH CC PDS);   Device: Phototherapy (Bright Light);   Drug: Melatonin CR
    Sponsors:   National Institutes of Health Clinical Center (CC);   National Human Genome Research Institute (NHGRI)
    Recruiting - verified June 2011
  • Pilot Study of a Multi-Drug Regimen for Severe Pulmonary Fibrosis in Hermansky-Pudlak Syndrome

    Conditions:   Hermansky-Pudlak Syndrome (HPS);   Pulmonary Fibrosis;   Oculocutaneous Albinism;   Platelet Storage Pool Deficiency;   Metabolic Disease
    Interventions:   Drug: Losartan;   Drug: Zileuton;   Drug: N-Acetylcysteine;   Drug: Prevastatin;   Drug: Erythromycin
    Sponsors:   National Institutes of Health Clinical Center (CC);   National Human Genome Research Institute (NHGRI)
    Recruiting - verified December 2010
  • Effect of EGCG on the Body's Response to Insulin

    Conditions:   Hypertension;   Obesity;   Type 2 Diabetes;   Insulin Resistance
    Interventions:   Drug: Dietary Supplement: epigallocatechin 3-gallate (EGCG);   Procedure: hyperinsulinemic isoglycemic glucose clamp;   Procedure: insulin-stimulated brachial artery blood flow;   Procedure: assess capillary recruitment in forearm skeletal muscle
    Sponsors:   University of Maryland;   University of Maryland;   Office of Dietary Supplements (ODS);   National Center for Complementary and Alternative Medicine (NCCAM)
    Recruiting - verified December 2011
  • BBBD Followed By Methotrexate and Carboplatin With or Without Trastuzumab in Treating Women With Breast Cancer That Has Spread to the Brain

    Conditions:   Brain and Central Nervous System Tumors;   Breast Cancer;   Cognitive/Functional Effects;   Drug/Agent Toxicity by Tissue/Organ;   Psychosocial Effects of Cancer and Its Treatment
    Interventions:   Biological: trastuzumab;   Drug: carboplatin;   Drug: methotrexate;   Drug: sodium thiosulfate
    Sponsors:   OHSU Knight Cancer Institute;   OHSU Knight Cancer Institute;   National Cancer Institute (NCI)
    Not yet recruiting - verified March 2012
  • Combination Chemotherapy With BBBD Followed By Sodium Thiosulfate in Treating Patients With Anaplastic Oligodendroglioma or Oligoastrocytoma

    Condition:   Brain and Central Nervous System Tumors
    Interventions:   Drug: Etoposide phosphate;   Drug: Melphalan;   Drug: Carboplatin;   Drug: Sodium thiosulfate;   Drug: Filgrastim;   Drug: Pegfilgrastim
    Sponsors:   OHSU Knight Cancer Institute;   OHSU Knight Cancer Institute;   National Cancer Institute (NCI)
    Recruiting - verified January 2012
  • Allogeneic Bone Marrow Transplantation Using Less Intensive Therapy

    Conditions:   Kidney Cancer;   Leukemia;   Lymphoma;   Multiple Myeloma and Plasma Cell Neoplasm;   Myelodysplastic Syndromes
    Interventions:   Biological: anti-thymocyte globulin;   Drug: cyclophosphamide;   Drug: cyclosporine;   Drug: fludarabine phosphate;   Drug: mycophenolate mofetil;   Procedure: stem cell transplantation;   Radiation: total-body irradiation;   Drug: methylprednisolone;   Drug: allopurinol;   Drug: filgrastim
    Sponsors:   Masonic Cancer Center, University of Minnesota;   Masonic Cancer Center, University of Minnesota
    Recruiting - verified April 2012
  • Rituximab&Methotrexate Chemotherapy w/BBBD & Sodium Thiosulfate Chemoprotection for Patients With Newly Diagnosed PCNSL

    Conditions:   Brain and Central Nervous System Tumors;   Lymphoma
    Interventions:   Drug: Rituxan;   Drug: Carboplatin;   Drug: Methotrexate;   Drug: Sodium thiosulfate;   Drug: Neupogen;   Drug: Neulasta;   Drug: Leucovorin
    Sponsors:   OHSU Knight Cancer Institute;   OHSU Knight Cancer Institute;   National Cancer Institute (NCI)
    Recruiting - verified January 2012
  • Treatment of Orthostatic Intolerance

    Conditions:   Tachycardia;   Chronic Orthostatic Intolerance
    Interventions:   Drug: Acetazolamide;   Drug: Atomoxetine;   Other: Baseline (No Drug);   Drug: Clonidine;   Drug: Entacapone;   Drug: Entacapone & Propranolol;   Drug: Atomoxetine & Propranolol;   Drug: Indomethacin;   Drug: Mecamylamine;   Drug: Isosorbide Dinitrate;   Dietary Supplement: Melatonin;   Drug: Midodrine;   Drug: Modafinil;   Drug: Octreotide;   Radiation: Placebo;   Drug: Propranolol;   Drug: Modafinil & Propranolol;   Drug: Sertraline;   Procedure: IV Saline;   Other: Drinking Water;   Device: Breathing Device;   Drug: memantine;   Device: Abdominal binder
    Sponsors:   Vanderbilt University;   Satish R. Raj;   National Institutes of Health (NIH)
    Recruiting - verified February 2012
  • A Randomized, Clinical Trial of Vitamin E and Memantine in Alzheimer's Disease

    Condition:   Alzheimer's Disease
    Interventions:   Drug: dl-alpha-tocopherol;   Drug: Memantine;   Drug: dl-alpha-tocopherol;   Drug: Memantine;   Drug: Placebo
    Sponsors:   Department of Veterans Affairs;   Department of Veterans Affairs;   Forest Laboratories;   DSM Nutritional Products, Inc.
    Recruiting - verified April 2012
  • Inhaled Nitric Oxide for Pediatric Painful Sickle Crisis

    Condition:   Sickle Cell Disease
    Interventions:   Drug: nitric oxide;   Drug: oxygen
    Sponsors:   Children's Hospital Boston;   Children's Hospital Boston;   FDA Office of Orphan Products Development
    Recruiting - verified July 2011
  • Treating Patients With High-Grade Glioma With IA Carboplatin-based Chemotherapy, With or Without Sodium Thiosulfate

    Conditions:   Brain and Central Nervous System Tumors;   Thrombocytopenia
    Interventions:   Drug: Carboplatin;   Drug: Cyclophosphamide;   Drug: Etoposide phosphate;   Drug: Etoposide;   Drug: Sodium thiosulfate
    Sponsors:   OHSU Knight Cancer Institute;   OHSU Knight Cancer Institute;   National Cancer Institute (NCI)
    Recruiting - verified January 2012
  • Urinary Vitamin C Loss in Diabetic Subjects

    Condition:   Diabetes Mellitus
    Intervention:  
    Sponsors:   National Institutes of Health Clinical Center (CC);   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
    Recruiting - verified October 2011
  • Investigating the Use of Quercetin on Glucose Absorption in Obesity, and Obesity With Type 2 Diabetes

    Conditions:   Diabetes Mellitus;   Obesity
    Intervention:   Procedure: Oral glucose tolerance test
    Sponsors:   National Institutes of Health Clinical Center (CC);   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
    Recruiting - verified March 2012
  • The Body's Affect on Vitamin C

    Condition:   Healthy
    Intervention:  
    Sponsors:   National Institutes of Health Clinical Center (CC);   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
    Recruiting - verified March 2012

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