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Aspirin

Aspirin

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  • PROMUS Element Plus US Post-Approval Study

    Condition:   Coronary Artery Disease
    Interventions:   Device: PROMUS Element Plus Coronary Stent System;   Drug: Aspirin;   Drug: P2Y12 antagonist
    Sponsors:   Boston Scientific Corporation;   Boston Scientific Corporation
    Not yet recruiting - verified May 2012
  • Therapeutic Control of Aspirin-Exacerbated Respiratory Disease (Aspirin)

    Conditions:   Asthma, Aspirin-Induced;   Aspirin Exacerbated Asthma
    Intervention:   Drug: Prasugrel
    Sponsors:   Brigham and Women's Hospital;   Elliot Israel, MD;   Brigham and Women's Hospital
    Not yet recruiting - verified May 2012
  • Patients Undergoing Percutaneous Coronary Intervention (PCI) Through Optimal Platelet Inhibition

    Conditions:   Percutaneous Coronary Intervention;   Dual Antiplatelet Therapy;   Aspirin;   Clopidogrel
    Intervention:  
    Sponsors:   Mount Sinai School of Medicine;   Mount Sinai School of Medicine;   Daiichi Sankyo Inc.;   Accumetrics, Inc.
    Recruiting - verified April 2012
  • NUTRITION: Natural Tocotrienol Against Ischemic Stroke Event

    Conditions:   Ischemic Stroke;   Transient Ischemic Attack (TIA)
    Intervention:   Other: Vitamin E tocotrienol (TCT) pills ; Low dose Aspirin
    Sponsors:   Ohio State University;   Chandan K Sen;   Government of Malaysia
    Recruiting - verified April 2012
  • A Study in Healthy Volunteers to Evaluate Effects of Pre-Medication or Slow Dose Titration on Flushing and Gastrointestinal Events

    Condition:   Healthy Volunteers
    Interventions:   Drug: Standard dose BG00012;   Drug: Aspirin placebo;   Drug: Aspirin;   Drug: Escalating doses of BG00012;   Drug: BG00012 placebo
    Sponsors:   Biogen Idec;   Biogen Idec
    Recruiting - verified April 2012
  • Efficacy of a Single Dose of Aspirin vs. Acetaminophen in Tension Type Headache

    Condition:   Headache
    Interventions:   Drug: BAY1019036;   Drug: Acetaminophen;   Drug: Placebo
    Sponsors:   Bayer;   Bayer
    Recruiting - verified May 2012
  • Early Prevention of Preeclampsia Study

    Condition:   Preeclampsia
    Interventions:   Drug: Aspirin;   Drug: placebo
    Sponsors:   Washington University School of Medicine;   Washington University School of Medicine
    Recruiting - verified March 2012
  • Lovaza's Effect on Clopidogrel in a Neuro Population

    Conditions:   Ischemic Stroke;   Transient Ischemic Attack
    Intervention:   Dietary Supplement: omega-3 polyunsaturated fatty acids (Lovaza)
    Sponsors:   Millard Fillmore Gates Hospital;   Millard Fillmore Gates Hospital;   Kaleida Health
    Recruiting - verified February 2012
  • Pharmacodynamic Evaluation of PL2200 Versus Enteric-Coated and Immediate Release Aspirin in Diabetic Patients

    Condition:   Diabetes Mellitus, Type 2
    Interventions:   Drug: PL2200 Aspirin Capsules;   Drug: Immediate-Release Aspirin Tablets;   Drug: Enteric-coated aspirin caplets
    Sponsors:   PLx Pharma;   PLx Pharma
    Recruiting - verified January 2012
  • LIPS-A: Lung Injury Prevention Study With Aspirin

    Condition:   Acute Respiratory Distress Syndrome
    Interventions:   Drug: Aspirin;   Drug: Lactose powder
    Sponsors:   Mayo Clinic;   Ognjen Gajic;   Beth Israel Deaconess Medical Center;   Montefiore Medical Center;   Vanderbilt University
    Not yet recruiting - verified January 2012
  • Web-based Support to Manage Arthritis Pain

    Conditions:   Osteoarthritis;   Rheumatoid Arthritis;   Ankylosing Spondylitis;   Other Arthritic Conditions (e.g., Psoriatic Arthritis)
    Intervention:   Behavioral: painACTION: Arthritis
    Sponsors:   Inflexxion, Inc.;   Inflexxion, Inc.
    Recruiting - verified October 2011
  • Pharmacogenomics of Anti-platelet Intervention-2 (PAPI-2) Study

    Conditions:   Cardiovascular Diseases;   Acute Coronary Syndrome
    Interventions:   Drug: clopidogrel;   Drug: prasugrel
    Sponsors:   University of Maryland;   University of Maryland;   National Heart, Lung, and Blood Institute (NHLBI)
    Recruiting - verified February 2012
  • Minocycline and Aspirin in the Treatment of Bipolar Depression

    Condition:   Bipolar Disorder Depression
    Interventions:   Drug: Minocycline;   Drug: Aspirin;   Drug: placebo
    Sponsors:   Laureate Institute for Brain Research, Inc.;   Laureate Institute for Brain Research, Inc.;   Stanley Medical Research Institute;   University of Oklahoma
    Recruiting - verified March 2012
  • Pomalidomide in Combination With High Dose Dexamethasone and Oral Cyclophosphamide

    Condition:   Myeloma
    Interventions:   Drug: Pomalidomide;   Drug: Dexamethasone;   Drug: Cyclophosphamide
    Sponsors:   H. Lee Moffitt Cancer Center and Research Institute;   H. Lee Moffitt Cancer Center and Research Institute;   Celgene Corporation
    Recruiting - verified May 2012
  • Aspirin Responsiveness in Women With Coronary Artery Disease

    Condition:   CAD
    Intervention:  
    Sponsors:   Creighton University;   Creighton University
    Recruiting - verified January 2012
  • Prevalence of Aspirin Resistance in Chronic Kidney Disease Patients

    Condition:   Chronic Kidney Disease
    Intervention:  
    Sponsors:   North Shore Long Island Jewish Health System;   Staten Island University Hospital
    Recruiting - verified April 2011
  • Phase I/II Amrubicin in Combo With Lenalidomide + Weekly Dexamethasone in Relapsed/Refractory Multiple Myeloma

    Condition:   Multiple Myeloma
    Interventions:   Drug: Amrubicin;   Drug: Lenalidomide;   Drug: Dexamethasone;   Drug: Aspirin
    Sponsors:   Stanford University;   Stanford University;   Celgene Corporation
    Recruiting - verified October 2011
  • Diabetic Treatment Adherence

    Condition:   Endocrine System Diseases
    Interventions:   Drug: Metformin;   Behavioral: Questionnaires
    Sponsors:   M.D. Anderson Cancer Center;   M.D. Anderson Cancer Center;   Agency for Healthcare Research and Quality (AHRQ)
    Recruiting - verified March 2012
  • Aspirin Resistance in Women With Migraine

    Conditions:   Episodic Migraine;   Chronic Migraine
    Interventions:   Drug: Aspirin (acetylsalicylic acid);   Drug: Placebo
    Sponsors:   Swedish Medical Center;   Swedish Medical Center;   University of Washington;   National Headache Foundation;   Wadsworth Foundation;   Accumetrics, Inc.
    Recruiting - verified July 2011
  • Randomized Trial of Pegylated Interferon Alfa-2a Versus Hydroxyurea in Polycythemia Vera (PV) and Essential Thrombocythemia (ET)

    Conditions:   High Risk Polycythemia Vera;   High Risk Essential Thrombocythemia
    Interventions:   Drug: PEGASYS;   Drug: Hydroxyurea;   Drug: Aspirin
    Sponsors:   Myeloproliferative Disorders-Research Consortium;   Myeloproliferative Disorders-Research Consortium;   National Cancer Institute (NCI);   Roche Pharma AG
    Recruiting - verified December 2011
  • Pegylated Interferon Alfa-2a Salvage Therapy in High Risk Polycythemia Vera (PV) or Essential Thrombocythemia (ET)

    Conditions:   High Risk Polycythemia Vera;   High Risk Essential Thrombocythemia
    Interventions:   Drug: PEGASYS;   Drug: Aspirin
    Sponsors:   Myeloproliferative Disorders-Research Consortium;   Myeloproliferative Disorders-Research Consortium;   National Cancer Institute (NCI);   Roche Pharma AG
    Recruiting - verified February 2012
  • Early Use of Rosuvastatin in Acute Coronary Syndromes: Targeting Platelet-Leukocyte Interactions

    Conditions:   Acute Coronary Syndrome;   Angioplasty, Transluminal, Percutaneous Coronary;   Hydroxymethylglutaryl-CoA Reductase Inhibitors;   Blood Platelets
    Interventions:   Drug: rosuvastatin;   Drug: placebo
    Sponsors:   University of Kentucky;   University of Kentucky
    Recruiting - verified March 2012
  • Aspirin and Plavix Following Coronary Artery Bypass Grafting

    Condition:   Coronary Graft Patency
    Interventions:   Drug: clopidogrel;   Drug: sugar pill
    Sponsors:   Brooke Army Medical Center;   Ahmad Slim;   Bristol-Myers Squibb
    Recruiting - verified February 2012
  • Prevention of Cardiovascular Events (eg, Death From Heart or Vascular Disease, Heart Attack, or Stroke) in Patients With Prior Heart Attack Using Ticagrelor Compared to Placebo on a Background of Aspirin

    Conditions:   Myocardial Infarction;   Cardiovascular Death;   Atherothrombosis;   Stroke
    Interventions:   Drug: Ticagrelor 90 mg;   Drug: Ticagrelor 60 mg;   Drug: Ticagrelor Placebo
    Sponsors:   AstraZeneca;   AstraZeneca
    Recruiting - verified May 2012
  • PeriOperative ISchemic Evaluation-2 Trial

    Condition:   Cardiovascular Disease
    Interventions:   Drug: Active Clonidine;   Drug: Placebo Clonidine;   Drug: Active ASA;   Drug: Placebo ASA
    Sponsors:   McMaster University;   Hamilton Health Sciences Corporation;   McMaster University
    Recruiting - verified December 2011
  • In-Vivo Bleeding Volume Test for Platelet-Aspirin Interaction

    Condition:   Healthy
    Interventions:   Procedure: Aspirin ingestion followed by doing a Bleeding Volume Test;   Procedure: Gatorade Placebo followed by Bleeding Volume Test.
    Sponsors:   Klein, Jeffrey A., M.D.;   Klein, Jeffrey A., M.D.
    Recruiting - verified June 2011
  • Aspirin in Reducing Events in the Elderly

    Conditions:   Functional Disability;   Dementia;   Heart Disease;   Stroke;   Cancer;   Bleeding
    Interventions:   Drug: 100 mg enteric-coated aspirin;   Drug: Placebo
    Sponsors:   Minneapolis Medical Research Foundation;   Minneapolis Medical Research Foundation;   National Health and Medical Research Council, Australia;   Bayer;   Monash University;   Berman Center for Outcomes and Clinical Research
    Recruiting - verified July 2011
  • Idiopathic Intracranial Hypertension Treatment Trial

    Condition:   Idiopathic Intracranial Hypertension
    Interventions:   Drug: Acetazolamide;   Drug: Placebo;   Behavioral: Formal weight loss counselling program
    Sponsors:   St. Luke's-Roosevelt Hospital Center;   St. Luke's-Roosevelt Hospital Center;   National Eye Institute (NEI);   University of Rochester;   University of Iowa;   University of California, Davis
    Recruiting - verified May 2012
  • Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) Trial

    Condition:   Ischemic Attack, Transient
    Interventions:   Drug: Clopidogrel;   Drug: placebo
    Sponsors:   University of California, San Francisco;   University of California, San Francisco;   Neurological Emergencies Treatment Trials Network (NETT);   Medical University of South Carolina;   The EMMES Corporation
    Recruiting - verified January 2012
  • Aspirin and Eflornithine in Treating Patients at High Risk for Colorectal Cancer

    Condition:   Familial Adenomatous Polyposis
    Interventions:   Drug: eflornithine (DFMO);   Drug: acetylsalicylic acid (aspirin);   Other: placebo;   Other: laboratory biomarker analysis;   Other: gene expression analysis;   Other: telephone-based intervention;   Other: immunohistochemistry staining method;   Other: reverse transcriptase-polymerase chain reaction;   Other: protein expression analysis
    Sponsors:   Mayo Clinic;   Mayo Clinic
    Recruiting - verified March 2012
  • Scripps Evaluation of Antiplatelet Therapies for Intermediate Duration With the Endeavor Stent (Seaside)

    Conditions:   Coronary Artery Disease;   Coronary Thrombosis
    Intervention:   Device: Medtronic Endeavor Stent
    Sponsors:   Scripps Health;   Scripps Health;   Medtronic
    Recruiting - verified July 2011
  • International PFO Consortium

    Conditions:   Stroke;   Transient Ischemic Attack
    Interventions:   Drug: Antithrombotic treatment;   Device: percutaneous device closure of PFO
    Sponsors:   University Hospital Inselspital, Berne;   University Hospital Inselspital, Berne;   University Hospital, Basel, Switzerland;   University of Lausanne Hospitals;   University Hospital, Geneva;   University Hospital, Zürich;   Triemli Hospital;   Cantonal Hospital of Aarau, Switzerland;   Alfried-Krupp Krankenhaus of Essen, Germany;   University Hospital, Essen;   Klinikum Worms gGmbH, Germany;   Tufts Medical Center;   Baystate Medical Center;   East Medical Center Tyler, Texas;   Universitaire Ziekenhuizen Leuven
    Recruiting - verified January 2012
  • Etanercept in Kawasaki Disease

    Conditions:   Mucocutaneous Lymph Node Syndrome;   Kawasaki Disease
    Interventions:   Drug: Etanercept;   Drug: Placebo
    Sponsors:   Seattle Children's Hospital;   Michael Portman;   FDA Office of Orphan Products Development;   Amgen
    Recruiting - verified April 2012
  • Trial of Aspirin and Arginine Restriction in Colorectal Cancer

    Condition:   Colorectal Cancer
    Intervention:   Drug: Aspirin
    Sponsors:   University of California, Irvine;   University of California, Irvine
    Recruiting - verified March 2012
  • Aspirin for Treatment of Multiple Sclerosis-Related Fatigue

    Condition:   Multiple Sclerosis
    Intervention:   Drug: Aspirin
    Sponsors:   Mayo Clinic;   Mayo Clinic;   National Multiple Sclerosis Society
    Recruiting - verified November 2011
  • Treatment of Supine Hypertension in Autonomic Failure

    Condition:   Hypertension
    Interventions:   Drug: Clonidine;   Drug: Nitroglycerin transdermal;   Drug: Dipyridamole/ Aspirin (Aggrenox);   Drug: Desmopressin (DDAVP);   Drug: Sildenafil;   Drug: Nifedipine;   Drug: Hydralazine;   Drug: Hydrochlorothiazide;   Drug: Placebo;   Drug: Bosentan;   Drug: Diltiazem;   Drug: Eplerenone;   Drug: guanfacine;   Dietary Supplement: L-arginine;   Drug: captopril;   Drug: carbidopa;   Drug: losartan;   Drug: metoprolol tartrate;   Drug: nebivolol hydrochloride;   Drug: prazosin hydrochloride;   Drug: tamsulosin hydrochloride;   Other: Head-up tilt.
    Sponsors:   Vanderbilt University;   Vanderbilt University
    Recruiting - verified May 2012

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