Brimonidine Clinical Trials

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A Safety and Efficacy Study of ALPHAGAN® P and LUMIGAN® in Subjects Previously Treated With Latanoprost for Glaucoma and Ocular Hypertension

Conditions: Glaucoma; Ocular Hypertension
Interventions: Drug: 0.1% brimonidine tartrate and 0.01% bimatoprost; Drug: 0.01% bimatoprost and 0.2% hypromellose
Sponsors: Allergan; Allergan
Recruiting - verified January 2012
Assessing the Efficacy and Tolerability of AZARGA® (Brinzolamide 1%/Timolol 0.5% Fixed Combination) as Replacement Therapy in Patients on COMBIGAN® (Brimonidine 0.2%/Timolol 0.5% Fixed Combination) Therapy in Latin America

Condition: Glaucoma
Intervention: Drug: Brinzolamide/Timolol Maleate Fixed Combination (AZARGA)
Sponsors: Alcon Research; Alcon Research
Recruiting - verified January 2012
Brinzolamide/Brimonidine Twice a Day (BID) Fixed Combination (FC) vs Brinzolamide BID and Brimonidine BID in Patients With Open Angle Glaucoma or Ocular Hypertension

Conditions: Open-angle Glaucoma; Ocular Hypertension
Interventions: Drug: Brinzolamide 1% / brimonidine 0.2% ophthalmic suspension; Drug: Brinzolamide 1% Eye drops, suspension BID (AZOPT); Drug: Brimonidine Tartrate
Sponsors: Alcon Research; Alcon Research
Recruiting - verified November 2011
Efficacy and Safety of Brinzolamide 1% / Brimonidine 0.2% Fixed Combination BID vs. Brinzolamide 1% BID Plus Brimonidine 0.2% BID

Condition: Open-angle Glaucoma or Ocular Hypertension
Interventions: Drug: Brinzolamide 1% / brimonidine 0.2% ophthalmic suspension; Other: Vehicle for masking purposes; Drug: Brinzolamide 1% ophthalmic suspension (AZOPT); Drug: Brimonidine 0.2% ophthalmic solution
Sponsors: Alcon Research; Alcon Research
Recruiting - verified November 2011
Effect of Alphagan on Retinal Blood Flow Autoregulation and Motion Detection in Patients With Normal Pressure Glaucoma

Condition: Glaucoma
Intervention: Drug: Alphagan (brimonidine) 0.15%
Sponsors: Massachusetts Eye and Ear Infirmary; Massachusetts Eye and Ear Infirmary
Recruiting - verified April 2012
Effect of Cosopt Versus Combigan on Retinal Vascular Autoregulation in Primary Open Angle Glaucoma (POAG)

Condition: Glaucoma
Interventions: Drug: Cosopt; Drug: Combigan
Sponsors: Massachusetts Eye and Ear Infirmary; Massachusetts Eye and Ear Infirmary
Recruiting - verified April 2012
Ciracadian Ocular Perfusion and Ocular Blood Flow

Condition: Glaucoma
Interventions: Drug: AZARGA; Drug: COMBIGAN
Sponsors: Alcon Research; Alcon Research
Recruiting - verified January 2012