Bystolic Clinical Trials

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Nebivolol and Endothelial Regulation of Fibrinolysis (NERF)

Conditions: Prehypertension; Hypertension
Interventions: Drug: Nebivolol; Drug: Metoprolol; Drug: Placebo
Sponsors: University of Colorado, Boulder; University of Colorado, Boulder; Forest Laboratories
Recruiting - verified May 2012
A Study Examining the Effects of Nebivolol Compared to Atenolol on Endothelial Function

Condition: Hypertension
Interventions: Drug: Nebivolol; Drug: atenolol; Drug: placebo
Sponsors: University of Minnesota - Clinical and Translational Science Institute; University of Minnesota - Clinical and Translational Science Institute; Forest Laboratories
Recruiting - verified January 2012
Study of the Efficacy and Safety of the Combination of Two FDA Approved Oral Medications, Nebivolol and Valsartan for Treatment of Stage 1 or 2 Hypertension

Conditions: Stage 1 Hypertension; Stage 2 Hypertension
Interventions: Drug: Nebivolol and Valsartan 1; Drug: Nebivolol and Valsartan 2; Drug: Nebivolol and Valsartan 3; Drug: Nebivolol 1; Drug: Nebivolol 2; Drug: Valsartan 1; Drug: Valsartan 2; Drug: Placebo
Sponsors: Forest Laboratories; Forest Laboratories
Recruiting - verified March 2012
Effects of Nebivolol on Skeletal Muscle During Exercise in Hypertensive Patients

Condition: Hypertension
Interventions: Drug: Metoprolol succinate; Drug: Nebivolol; Drug: Hydrochlorothiazide; Drug: DEFINITY®; Procedure: Non-invasive measurement of Cardiac Output (CO); Procedure: Flow mediated vasodilation; Procedure: Endothelial cell collection; Procedure: Microvascular perfusion assessment using Definity
Sponsors: University of Texas Southwestern Medical Center; University of Texas Southwestern Medical Center; Forest Laboratories
Recruiting - verified April 2012
Comparison of Nebivolol and Metoprolol With Exercise and Angiotensin II in Hypertensive Patients

Condition: Hypertension
Interventions: Drug: Metoprolol succinate; Drug: Nebivolol; Procedure: Forearm blood flow; Procedure: Microneurography; Procedure: Rhythmic handgrip exercise; Procedure: Lower body negative pressure; Drug: Angiotensin II
Sponsors: University of Texas Southwestern Medical Center; University of Texas Southwestern Medical Center; Forest Laboratories
Recruiting - verified April 2012
Comparison of 2 Beta Blocker Drugs on Peripheral Arterial Disease in Patients With High Blood Pressure

Conditions: Peripheral Artery Disease; Hypertension
Interventions: Drug: nebivolol; Drug: Metoprolol succinate
Sponsors: Thomas Jefferson University; Thomas Jefferson University; Forest Laboratories
Recruiting - verified December 2011
The Impact of Nebivolol Versus Metoprolol on Quality of Life

Conditions: Transplant; Failure, Kidney; Hypertension
Interventions: Drug: Nebivolol; Drug: Metoprolol succinate
Sponsors: Brigham and Women's Hospital; Brigham and Women's Hospital; Forest Laboratories; Lahey Clinic
Recruiting - verified February 2012
Nebivolol and the Endothelin (ET)-1 System

Conditions: Prehypertension; Hypertension
Interventions: Drug: Nebivolol; Drug: Metoprolol; Drug: Placebo
Sponsors: University of Colorado, Boulder; University of Colorado, Boulder; Forest Laboratories
Recruiting - verified May 2012
Nebivolol in the Supine Hypertension of Autonomic Failure

Conditions: Hypertension; Pure Autonomic Failure; Multiple System Atrophy
Interventions: Drug: Placebo; Drug: Nebivolol 5 mg; Drug: metoprolol tartrate 50 mg; Drug: Sildenafil25 mg
Sponsors: Vanderbilt University; Vanderbilt University; Forest Laboratories
Recruiting - verified May 2012
Alternative in Beta Blocker Intolerance: The ABBI Trial

Condition: Coronary Artery Disease
Intervention: Drug: Nebivolol
Sponsors: Minneapolis Heart Institute Foundation; Minneapolis Heart Institute Foundation; Forest Laboratories
Recruiting - verified June 2011
Treatment of Supine Hypertension in Autonomic Failure

Condition: Hypertension
Interventions: Drug: Clonidine; Drug: Nitroglycerin transdermal; Drug: Dipyridamole/ Aspirin (Aggrenox); Drug: Desmopressin (DDAVP); Drug: Sildenafil; Drug: Nifedipine; Drug: Hydralazine; Drug: Hydrochlorothiazide; Drug: Placebo; Drug: Bosentan; Drug: Diltiazem; Drug: Eplerenone; Drug: guanfacine; Dietary Supplement: L-arginine; Drug: captopril; Drug: carbidopa; Drug: losartan; Drug: metoprolol tartrate; Drug: nebivolol hydrochloride; Drug: prazosin hydrochloride; Drug: tamsulosin hydrochloride; Other: Head-up tilt.
Sponsors: Vanderbilt University; Vanderbilt University
Recruiting - verified May 2012