- Condition: Alcohol Consumption
Interventions: Behavioral: Brief Alcohol Intervention; Other: Lifestyle brochures
Sponsors: Department of Veterans Affairs; Department of Veterans Affairs
Not yet recruiting - verified May 2012 - Condition: Labor Pain
Intervention: Drug: Hydromorphone
Sponsors: Emory University; Emory University
Not yet recruiting - verified May 2012 - Conditions: Atrial Fibrillation; Electrical Cardioversion
Interventions: Drug: Magnesium Sulfate; Other: Placebo
Sponsors: State University of New York at Buffalo; State University of New York at Buffalo
Recruiting - verified May 2012 - Condition: Depression
Intervention: Dietary Supplement: Magnesium sulfate
Sponsors: University of Miami; University of Miami; Life Extension Foundation
Recruiting - verified May 2012 - Condition: Treatment-Resistant Depression
Intervention:
Sponsors: Mclean Hospital; Mclean Hospital; Pfizer; Massachusetts General Hospital
Not yet recruiting - verified May 2012 - Condition: Pediatric Burns
Interventions: Drug: Melatonin; Other: placebo
Sponsors: Shriners Hospitals for Children; Shriners Hospitals for Children
Not yet recruiting - verified May 2012 - Conditions: Sleep; Burns
Intervention:
Sponsors: Shriners Hospitals for Children; Shriners Hospitals for Children; Children's Hospital Medical Center, Cincinnati
Recruiting - verified May 2012 - Conditions: Pain, Postoperative; Postoperative Nausea and Vomiting
Interventions: Drug: Tumescent solution with dilute lidocaine and epinephrine; Drug: Tumescent Solution with dilute epinephrine
Sponsors: University of Wisconsin, Madison; University of Wisconsin, Madison
Not yet recruiting - verified May 2012 - Conditions: Colorectal Disorders; Observation of Neuromuscular Block
Interventions: Drug: 0.2% ropivacaine; Drug: Saline
Sponsors: Stamford Hospital; Stamford Hospital
Recruiting - verified May 2012 - Condition: Schizophrenia
Interventions: Drug: risperidone-SABER; Other: ZX003:risperidone-SABER and the DosePro System; Drug: risperidone-SABER
Sponsors: Zogenix, Inc.; Zogenix, Inc.
Not yet recruiting - verified May 2012 - Condition: Fibromyalgia
Interventions: Drug: Tramadol; Drug: Placebo; Behavioral: Cognitive Behavior Therapy for FM; Behavioral: Health Education
Sponsors: University of Washington; University of Washington
Not yet recruiting - verified May 2012 - Condition: Morbid Obesity
Intervention: Drug: propofol
Sponsors: Stanford University; Stanford University
Recruiting - verified May 2012 - Condition: Obesity
Intervention: Drug: Propofol, Fentanyl
Sponsors: Stanford University; Stanford University; National Institute of General Medical Sciences (NIGMS)
Recruiting - verified May 2012 - Conditions: Chronic Pain; Opioid Addiction
Interventions: Other: Yoga; Behavioral: Educational Counseling
Sponsors: Yale University; Yale University
Recruiting - verified April 2012 - Conditions: Abdominal Muscles/Ultrasonography; Adult; Anesthetics, Local/Administration & Dosage; Ropivacaine/Administration & Dosage; Ropivacaine/Analogs & Derivatives; Cesarean Section; Humans; Nerve Block/Methods; Pain Measurement/Methods; Pain, Postoperative/Prevention & Control; Ultrasonography, Interventional
Interventions: Device: TAP catheter; Drug: intrathecal morphine
Sponsors: Stamford Anesthesiology Services, PC; Stamford Anesthesiology Services, PC; I-Flow
Recruiting - verified May 2012 - Conditions: Active Ethanol and Active Iomazenil; Active Ethanol and Placebo Iomazenil; Placebo Ethanol and Placebo Iomazenil; Placebo Ethanol and Active Iomazenil
Interventions: Drug: Ethanol; Drug: Iomazenil
Sponsors: Department of Veterans Affairs; Department of Veterans Affairs
Not yet recruiting - verified April 2012 - Conditions: Pain; Otitis Media
Interventions: Drug: benzocaine; Drug: placebo
Sponsors: Arbor Pharmaceuticals, Inc.; Arbor Pharmaceuticals, Inc.
Recruiting - verified May 2012 - Condition: Acute Low Back Pain
Interventions: Drug: Naproxen; Drug: Cyclobenzaprine; Drug: Oxycodone/ acetaminophen
Sponsors: Montefiore Medical Center; Montefiore Medical Center
Recruiting - verified April 2012 - Conditions: Fabry Disease; Neuropathic Pain
Interventions: Drug: Gabapentin; Drug: placebo
Sponsors: University of Minnesota - Clinical and Translational Science Institute; University of Minnesota - Clinical and Translational Science Institute; Genzyme
Recruiting - verified April 2012 - Conditions: Anterior Cruciate Ligament Reconstruction; Regional Anesthesia, Saphenous Nerve Block
Interventions: Drug: Bupivacaine Only; Drug: Bupivacaine with 2 ml of Dexamethasone; Drug: Bupivacaine with 4 mg of Dexamethasone
Sponsors: Hospital for Special Surgery, New York; Hospital for Special Surgery, New York
Not yet recruiting - verified April 2012 - An Open Label Pilot Study of Adjunctive Asenapine for the Treatment of Posttraumatic Stress DisorderCondition: Posttraumatic Stress Disorder
Intervention: Drug: Adjunctive asenapine
Sponsors: Tuscaloosa Research & Education Advancement Corporation; Lori Davis, MD; Merck
Not yet recruiting - verified April 2012 - Condition: Melatonin Suppression
Intervention: Radiation: Visible light
Sponsors: Brigham and Women's Hospital; Brigham and Women's Hospital; Biological Illumination LCC
Not yet recruiting - verified April 2012 - Conditions: Back Pain; Osteoarthritis
Interventions: Other: Opioid-intensive prescribing strategy; Other: Opioid-avoidant prescribing strategy
Sponsors: Department of Veterans Affairs; Department of Veterans Affairs
Not yet recruiting - verified April 2012 - Condition: Stress Urinary Incontinence
Interventions: Drug: Bupivicaine + epinephrine; Drug: Sodium chloride + epinephrine
Sponsors: University of Massachusetts, Worcester; University of Massachusetts, Worcester
Recruiting - verified April 2012 - Conditions: Pharmacokinetics of Isavuconazole; Pharmacokinetics of Methadone; Healthy Volunteers
Interventions: Drug: Isavuconazole; Drug: Methadone
Sponsors: Astellas Pharma Inc; Astellas Pharma Global Development, Inc.; Basilea Pharmaceutica International Ltd
Recruiting - verified April 2012 - Conditions: Regional Block for Pain Control; Supraclavicular Block; Ultrasound Guided Block; Block Additive
Intervention: Drug: Buprenorphine
Sponsors: University of Wisconsin, Madison; University of Wisconsin, Madison
Recruiting - verified April 2012 - Condition: Pain
Interventions: Drug: fentanyl; Drug: fentanyl, sufentanil
Sponsors: Pacira Pharmaceuticals, Inc; Pacira Pharmaceuticals, Inc
Recruiting - verified April 2012 - Condition: Breast Augmentation
Interventions: Drug: Morphine Sulfate; Drug: morphine sulfate, hydromorphone HCl
Sponsors: Pacira Pharmaceuticals, Inc; Pacira Pharmaceuticals, Inc
Recruiting - verified May 2012 - Condition: Alcoholism
Interventions: Drug: Ondansetron + Brief Behavioral Enhancement Treatment; Drug: Placebo + Brief Behavioral Enhancement Treatment
Sponsors: University of Virginia; Bankole Johnson; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Not yet recruiting - verified May 2012 - Condition: Major Depressive Disorder
Intervention: Drug: Ketamine
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified April 2012 - Condition: Cigarette Smoking
Interventions: Drug: Nicotine replacement therapy - transdermal nicotine patch; Behavioral: Tailored behavioral intervention; Behavioral: Tobacco quitline referral; Drug: Nicotine replacement therapy - nicotine gum; Drug: Nicotine replacement therapy - nicotine lozenge; Drug: Bupropion SR; Drug: Varenicline; Drug: Combination pharmacotherapy - transdermal nicotine patch + nicotine gum; Drug: Combination pharmacotherapy - transdermal nicotine patch + nicotine lozenge; Drug: Combination pharmacotherapy - transdermal nicotine patch + bupropion; Behavioral: Alcohol use risk reduction; Behavioral: Behavioral activation for the treatment of depression; Behavioral: Behavioral management of post-cessation weight gain
Sponsors: University of Iowa; University of Iowa; Department of Veterans Affairs
Not yet recruiting - verified May 2012 - Condition: AOD Effects and Consequences
Interventions: Drug: Alprazolam; Drug: Dextroamphetamine
Sponsors: Mclean Hospital; Mclean Hospital
Not yet recruiting - verified April 2012 - Condition: Pain on Propofol IV Injection
Interventions: Device: lidocaine/tetracaine transdermal patch (NDC 43469-864-01); Drug: Gebauer's Ethyl Chloride
Sponsors: The University of Texas Health Science Center, Houston; The University of Texas Health Science Center, Houston; ZARS Pharma Inc.
Recruiting - verified April 2012 - Condition: Laparoscopic Appendectomy
Interventions: Drug: Ropivacaine; Drug: Bupivacaine
Sponsors: Nationwide Children's Hospital; Nationwide Children's Hospital
Not yet recruiting - verified April 2012 - Condition: Cocaine Dependence
Interventions: Drug: Oxytocin; Drug: Saline
Sponsors: Medical University of South Carolina; Medical University of South Carolina
Not yet recruiting - verified April 2012 - Condition: Healthy
Interventions: Drug: Ondansetron; Drug: Ondansetron + Hylenex; Drug: Zofran ODT; Drug: Ondansetron solution
Sponsors: Halozyme Therapeutics; Halozyme Therapeutics
Recruiting - verified April 2012 - Condition: Pain
Intervention: Drug: 3% mepivacaine/2% lidocaine with 1:100,000 epinephrine combo
Sponsors: Ohio State University; Ohio State University
Not yet recruiting - verified April 2012 - Conditions: Post-anesthesia Recovery; Orientation
Interventions: Drug: Ketamine; Drug: Methohexital
Sponsors: University of New Mexico; University of New Mexico
Recruiting - verified March 2012 - Condition: Anesthetic Effectiveness
Intervention:
Sponsors: Ohio State University; Ohio State University
Not yet recruiting - verified March 2012 - Condition: Mucositis
Intervention: Drug: Ketamine
Sponsors: West Virginia University; Aaron Cumpston, PharmD
Recruiting - verified March 2012 - Condition: Patients Undergoing Elective Total Joint Arthroplasty
Interventions: Other: ultrasound guided placement spinal block; Other: standard spinal anesthesia
Sponsors: The Cleveland Clinic; The Cleveland Clinic
Recruiting - verified April 2012 - Conditions: Prostate Cancer; Robotic Prostatectomy; Foley Catheter Discomfort
Interventions: Drug: Bupivacaine; Drug: Saline
Sponsors: Columbia University; Columbia University
Recruiting - verified March 2012 - Conditions: Alcohol Abuse; Schizophrenia; Bipolar Disorder; Major Depressive Disorder
Intervention: Behavioral: Contingency Management
Sponsors: University of Washington; University of Washington
Not yet recruiting - verified March 2012 - Condition: Depressive Disorder, Major
Intervention: Behavioral: Medlink system
Sponsors: National Institute of Mental Health (NIMH); National Institute of Mental Health (NIMH)
Not yet recruiting - verified March 2012 - Condition: Advanced Solid Tumors, Excluding Breast Cancer
Interventions: Drug: caffeine; Drug: diclofenac; Drug: omeprazole; Drug: midazolam; Drug: TKI258
Sponsors: Novartis; Novartis Pharmaceuticals
Not yet recruiting - verified May 2012 - Condition: Substance-Related Disorders
Intervention: Drug: naltrexone for extended release injectable suspension
Sponsors: Rhode Island Hospital; Rhode Island Hospital; National Institute on Drug Abuse (NIDA); Alkermes
Recruiting - verified March 2012 - Condition: Subarachnoid Hemorrhage, Aneurysmal
Interventions: Drug: Dexmedetomidine; Drug: propofol
Sponsors: University of Cincinnati; University of Cincinnati
Recruiting - verified March 2012 - Condition: Chronic Pain
Intervention:
Sponsors: Brigham and Women's Hospital; Brigham and Women's Hospital
Recruiting - verified March 2012 - Condition: Usage of Prescription Opioids
Intervention:
Sponsors: Analgesic Solutions; Analgesic Solutions
Not yet recruiting - verified March 2012 - Condition: Schizophrenia
Intervention: Drug: Paliperidone
Sponsors: University of Maryland; University of Maryland
Recruiting - verified March 2012 - Condition: Maternal Opioid Dependency During Pregnancy
Intervention: Drug: Buprenorphine
Sponsors: Johns Hopkins University; Johns Hopkins University
Recruiting - verified March 2012 - Condition: Low Back Pain
Interventions: Drug: Methadone; Drug: Buprenorphine/naloxone
Sponsors: State University of New York at Buffalo; State University of New York at Buffalo
Recruiting - verified March 2012 - Condition: Major Depressive Disorder
Interventions: Drug: Ketamine; Drug: Ketamine; Drug: Ketamine; Drug: Ketamine; Drug: Ketamine; Drug: Saline
Sponsors: Columbia University; Columbia University; National Institute of Mental Health (NIMH)
Recruiting - verified March 2012 - Condition: Epilepsy
Intervention:
Sponsors: Weill Medical College of Cornell University; Weill Medical College of Cornell University
Recruiting - verified April 2012 - Conditions: Substance-related Disorders; HIV Risk Behavior
Interventions: Behavioral: Therapeutic Workplace; Drug: Methadone
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute on Drug Abuse (NIDA)
Not yet recruiting - verified March 2012 - Condition: Management of Moderate to Severe Pain
Interventions: Drug: ALO-02; Drug: Naltrexone block; Drug: ALO-02; Drug: Naltrexone block; Drug: OxyContin; Drug: Naltrexone block
Sponsors: Pfizer; Pfizer
Recruiting - verified April 2012 - Condition: Schizophrenia
Interventions: Drug: Paliperidone IR (Period 1); Drug: Paliperidone palmitate F015 (Panel A: treatment goup 1); Drug: Paliperidone palmitate F015 (Panel A: treatment goup 2); Drug: Paliperidone palmitate F015 (Panel B: treatment goup 1); Drug: Paliperidone palmitate F015 (Panel B: treatment goup 2); Drug: Paliperidone palmitate F015 (Panel B: treatment goup 3); Drug: Paliperidone palmitate F015 (Panel B: treatment goup 4); Drug: Paliperidone palmitate F015 (Panel B: treatment goup 5); Drug: Paliperidone palmitate F016; Drug: Paliperidone palmitate F015 (Panel D: treatment goup 1); Drug: Paliperidone palmitate F015 (Panel D: treatment goup 2); Drug: Paliperidone palmitate F015 (Panel D: treatment goup 3); Drug: Paliperidone palmitate F015 (Panel D: treatment goup 4)
Sponsors: Janssen Research & Development, LLC; Janssen Research & Development, LLC
Recruiting - verified May 2012 - Condition: Nausea and Vomiting
Interventions: Drug: lorazepam; Drug: diphenhydramine hydrochloride; Drug: haloperidol; Other: placebo
Sponsors: Virginia Commonwealth University; Virginia Commonwealth University; National Cancer Institute (NCI)
Recruiting - verified March 2012 - Condition: Small Cell Lung Carcinoma
Intervention: Drug: lithium carbonate
Sponsors: Washington University School of Medicine; Washington University School of Medicine
Recruiting - verified May 2012 - Condition: Management of Moderate to Severe Pain
Interventions: Drug: Oxycodone; Drug: Oxycodone; Drug: Oxycodone; Drug: Oxycodone; Drug: Oxycodone
Sponsors: Pfizer; Pfizer
Recruiting - verified April 2012 - Conditions: Depression; Alcohol Dependence
Intervention: Drug: Ketalar (ketamine)
Sponsors: Yale University; Yale University; VA Connecticut Healthcare System
Recruiting - verified April 2012 - Condition: Advanced Cancers
Interventions: Drug: Temsirolimus; Drug: Bevacizumab; Drug: Valproic Acid; Drug: Cetuximab
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center
Recruiting - verified March 2012 - Condition: Opiate Dependence
Interventions: Drug: Vivitrol; Behavioral: Employment based opiate abstinence reinforcement; Other: Usual Care Control
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute on Drug Abuse (NIDA)
Not yet recruiting - verified March 2012 - Condition: General Anesthesia
Intervention: Drug: propofol
Sponsors: Ethicon Endo-Surgery; Ethicon Endo-Surgery
Recruiting - verified March 2012 - Condition: Opioid Dependence
Interventions: Behavioral: Distress Tolerance; Behavioral: Health Education
Sponsors: Butler Hospital; Butler Hospital
Not yet recruiting - verified March 2012 - Condition: Postoperative Pain
Interventions: Drug: Methadone; Drug: Hydromorphone
Sponsors: NorthShore University HealthSystem Research Institute; NorthShore University HealthSystem Research Institute
Recruiting - verified March 2012 - Conditions: Ability to Influence Behavior; Information Systems
Interventions: Behavioral: Notification through anesthesia system; Behavioral: No notification
Sponsors: Mount Sinai School of Medicine; Mount Sinai School of Medicine
Recruiting - verified March 2012 - Condition: Shoulder Pain
Interventions: Procedure: Superficial Cervical Plexus Block; Drug: Bupivacaine
Sponsors: University of Washington; University of Washington
Not yet recruiting - verified March 2012 - Condition: Degenerative Joint Disease of Hip and Knee.
Interventions: Drug: Placebo; Drug: Gapabentin
Sponsors: University of Medicine and Dentistry New Jersey; University of Medicine and Dentistry New Jersey
Recruiting - verified March 2012 - Conditions: Bipolar I Disorder; Bipolar II Disorder
Interventions: Drug: Lithium/Lithium Carbonate; Drug: Divalproex; Drug: Lamotrigine; Drug: Quetiapine
Sponsors: The University of Texas Health Science Center at San Antonio; The University of Texas Health Science Center at San Antonio; National Institute of Mental Health (NIMH)
Recruiting - verified May 2012 - Condition: Traumatic Rib Fracture
Interventions: Procedure: Paravertebral Block; Procedure: Intercostal Nerve Block
Sponsors: Brigham and Women's Hospital; Brigham and Women's Hospital
Recruiting - verified May 2012 - Condition: Informed Consent
Intervention: Other: Phone call explaining the research project
Sponsors: NorthShore University HealthSystem Research Institute; NorthShore University HealthSystem Research Institute
Recruiting - verified March 2012 - Condition: Hip Fracture
Interventions: Procedure: Femoral Nerve Catheterization; Procedure: Intravenous Opioids
Sponsors: Ochsner Health System; Leslie Thomas; American Society of Anesthesiologists
Recruiting - verified March 2012 - Conditions: Pain, Postoperative; Chronic Pain
Interventions: Drug: Methadone; Drug: Fentanyl
Sponsors: NorthShore University HealthSystem Research Institute; NorthShore University HealthSystem Research Institute
Recruiting - verified February 2012 - Condition: Healthy Controls
Interventions: Radiation: Integrated MR-PET scan; Drug: Ketorolac; Drug: Morphine
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified April 2012 - Condition: Healthy Volunteers
Intervention: Drug: Lidocaine 7% + Tetracaine 7% cream
Sponsors: Galderma; Galderma
Recruiting - verified May 2012 - Condition: Healthy Volunteers
Interventions: Drug: Midazolam; Drug: vandetanib
Sponsors: AstraZeneca; AstraZeneca
Recruiting - verified April 2012 - Conditions: Abortion, Induced; Pain Management
Interventions: Drug: Lidocaine; Drug: Normal Saline
Sponsors: University of North Carolina, Chapel Hill; University of North Carolina, Chapel Hill
Recruiting - verified March 2012 - Condition: Shoulder Pain
Interventions: Drug: Synera® (lidocaine 70 mg and tetracaine 70 mg) topical patch; Drug: Triamcinolone Acetonide
Sponsors: Injury Care Medical Center; Injury Care Medical Center; Nuvo Research Inc.
Recruiting - verified March 2012 - Condition: Post-Operative Pain
Interventions: Drug: Sufentanil NanoTab PCA System/15 mcg; Drug: Placebo Sufentanil NanoTab PCA System
Sponsors: AcelRx Pharmaceuticals, Inc.; AcelRx Pharmaceuticals, Inc.
Recruiting - verified May 2012 - Condition: Post-Operative Pain
Interventions: Drug: Sufentanil NanoTab PCA System/15 mcg; Drug: morphine IV PCA
Sponsors: AcelRx Pharmaceuticals, Inc.; AcelRx Pharmaceuticals, Inc.
Recruiting - verified April 2012 - Condition: Postoperative Pain.
Interventions: Drug: Subpleural pain catheter with infusion of 0.125% bupivacaine; Drug: Standard acute pain management
Sponsors: Inova Health Care Services; Inova Health Care Services
Not yet recruiting - verified February 2012 - Conditions: Abdomen, Acute; Other Acute Pain; Flank Pain, Acute; Back Pain, Acute; Extremity Pain, Acute
Interventions: Drug: Ketamine; Drug: Morphine
Sponsors: Brooke Army Medical Center; Brooke Army Medical Center; U.S. Air Force Office of the Surgeon General
Recruiting - verified February 2012 - Conditions: Shoulder Pain; Injury of Shoulder Region; Disorder of Shoulder; Disorder of Rotator Cuff; Disorder of Tendon of Biceps
Interventions: Drug: Dexamethasone; Drug: Bupivacaine
Sponsors: Lifespan; Lifespan; Tufts Medical Center; United States Naval Medical Center, Portsmouth
Not yet recruiting - verified March 2012 - Conditions: Cocaine Dependence; Cocaine Addiction; Cocaine Abuse; Substance Abuse
Interventions: Behavioral: Sitting; Behavioral: Running; Behavioral: Walking
Sponsors: Baylor College of Medicine; Baylor College of Medicine; National Institute on Drug Abuse (NIDA)
Recruiting - verified May 2012 - Conditions: Heroin Dependence; Opioid-Related Disorders
Intervention:
Sponsors: Wayne State University; Wayne State University; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Condition: Cancer of the Cervix
Interventions: Drug: Granisetron; Drug: Ondansetron; Behavioral: Questionnaires; Behavioral: Study Drug Diary
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center; Sancuso
Recruiting - verified March 2012 - Conditions: Postoperative Pain; Paracervical Block; Laparoscopic Gynecologic Surgery
Interventions: Drug: Bupivacaine with epinephrine; Drug: Normal Saline
Sponsors: Mount Sinai School of Medicine; Mount Sinai School of Medicine
Recruiting - verified February 2012 - Conditions: Opioid Withdrawal; Physical Dependence
Intervention: Drug: Ondansetron
Sponsors: Stanford University; Stanford University; National Institute on Drug Abuse (NIDA)
Recruiting - verified March 2012 - Condition: Pain
Interventions: Drug: Lidocaine; Drug: Placebo
Sponsors: University of Pittsburgh; University of Pittsburgh; Society of Family Planning
Not yet recruiting - verified February 2012 - Condition: Drug Induced Constipation
Interventions: Drug: Nektar 118; Drug: Quinidine; Drug: Quinidine placebo; Drug: Morphine
Sponsors: AstraZeneca; AstraZeneca
Recruiting - verified March 2012 - Condition: Hot Flashes in Men With Prostate Cancer Receiving Androgen Ablation Therapy
Interventions: Drug: Gabapentin; Drug: Venlafaxine
Sponsors: University of Wisconsin, Madison; University of Wisconsin, Madison
Recruiting - verified February 2012 - Condition: Stroke
Intervention: Other: Inspired oxygen fraction / end tidal carbon dioxide
Sponsors: University of Michigan; University of Michigan
Not yet recruiting - verified February 2012 - Condition: Postoperative Pain
Intervention: Drug: Bupivicaine Infusion
Sponsors: Chang, Steve S., M.D.; Chang, Steve S., M.D.
Recruiting - verified February 2012 - Condition: Healthy
Interventions: Drug: Lacosamide (LCM); Drug: Carbamazepine Immediate Release (CBZ-IR)
Sponsors: UCB, Inc.; UCB, Inc.
Recruiting - verified May 2012 - Condition: Tonsillectomy
Interventions: Drug: Dexmedetomidine; Other: Placebo
Sponsors: Children's Hospital of Pittsburgh; Children's Hospital of Pittsburgh; Hospira, Inc.
Recruiting - verified February 2012 - Conditions: Abscess; Pain
Interventions: Drug: Intranasal Fentanyl; Drug: Intravenous Morphine
Sponsors: Columbia University; Columbia University
Recruiting - verified March 2012 - Conditions: CA2 and CA3 Residents Doing a Two Month Rotation in; Pediatric Anesthesia Department
Interventions: Other: Feedback group; Other: Control group
Sponsors: The Cleveland Clinic; The Cleveland Clinic
Recruiting - verified January 2012 - Condition: Bipolar Disorder
Interventions: Drug: Lithium; Drug: Quetiapine
Sponsors: University Hospital Case Medical Center; University Hospital Case Medical Center
Recruiting - verified January 2012 - Condition: Asthma
Interventions: Drug: Magnesium Sulfate; Drug: Placebo
Sponsors: University of Louisville; University of Louisville
Recruiting - verified January 2012 - Conditions: Ultrasound; CT Scans; MRIs
Interventions: Drug: Dexmedetomidine; Drug: Midazolam; Drug: Fentanyl
Sponsors: Hospira, Inc.; Hospira, Inc.
Recruiting - verified April 2012 - Condition: Opioid-Related Disorders
Interventions: Drug: Pioglitazone; Drug: Placebo
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified November 2011 - Condition: Post-Traumatic Stress Disorder
Interventions: Drug: Tramadol; Drug: Placebo
Sponsors: INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium; INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium; U.S. Army Medical Research and Materiel Command
Recruiting - verified January 2012 - Condition: Myringotomy
Intervention: Drug: Dexmedetomidine
Sponsors: University of Iowa; University of Iowa
Recruiting - verified February 2012 - Condition: Malignant Neoplasm
Interventions: Drug: placebo administration; Drug: EMLA; Drug: propofol; Drug: fentanyl citrate
Sponsors: Comprehensive Cancer Center of Wake Forest University; Comprehensive Cancer Center of Wake Forest University; National Cancer Institute (NCI)
Recruiting - verified March 2012 - Condition: Schizophrenia
Interventions: Drug: PP3M 175 mg eq.; Drug: PP3M 263 mg eq.; Drug: PP3M 350 mg eq.; Drug: PP3M 525 mg eq.; Drug: Placebo (20% Intralipid); Drug: PP1M 50 mg eq.; Drug: PP1M 75 mg eq.; Drug: PP1M 100 mg eq.; Drug: PP1M 150 mg eq.
Sponsors: Janssen Research & Development, LLC; Janssen Research & Development, LLC
Not yet recruiting - verified April 2012 - Conditions: Advanced Cancers; Dyspnea
Interventions: Drug: Fentanyl; Other: Placebo; Other: Walking Tests; Behavioral: Questionnaires
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center
Recruiting - verified April 2012 - Conditions: Pain; Total Knee Arthroplasty
Interventions: Drug: Dexamethasone; Drug: Ropivacaine
Sponsors: University of New Mexico; University of New Mexico
Not yet recruiting - verified April 2012 - Condition: Asthma
Intervention: Drug: Nebulized magnesium sulfate
Sponsors: University of Texas Southwestern Medical Center; University of Texas Southwestern Medical Center
Recruiting - verified September 2011 - Condition: Rotator Cuff Tear
Interventions: Device: Ivivi Torino II; Device: Inactive Sham device
Sponsors: Amp Orthopedics, Inc.; Amp Orthopedics, Inc.
Recruiting - verified January 2012 - Condition: Onset and Duration of a Digital Nerve Block With 2 Local Anesthesthetics.
Interventions: Drug: Lidocaine; Drug: Bupivacaine
Sponsors: University of California, San Francisco; University of California, San Francisco
Recruiting - verified February 2012 - Conditions: Hypotension; Anesthesia
Intervention:
Sponsors: Milton S. Hershey Medical Center; Milton S. Hershey Medical Center
Not yet recruiting - verified January 2012 - Condition: Suicidal Ideation
Interventions: Drug: Ketamine; Drug: Midazolam
Sponsors: Mount Sinai School of Medicine; James Murrough
Recruiting - verified January 2012 - Condition: Anesthesia
Interventions: Drug: Midazolam; Drug: Fentanyl; Drug: Morphine
Sponsors: Hospira, Inc.; Hospira, Inc.
Recruiting - verified April 2012 - Condition: Postoperative Nausea and Vomiting
Interventions: Drug: Ondansetron; Drug: Vestipitant
Sponsors: Octagon Research Solutions, Inc.; Octagon Research Solutions, Inc.
Recruiting - verified May 2012 - Condition: Chronic Pain
Intervention: Drug: Hydrocodone
Sponsors: NEMA Research, Inc.; NEMA Research, Inc.; Covidien; International Clinical Research Institute
Recruiting - verified April 2012 - Condition: Solid Tumors
Interventions: Drug: tivantinib; Drug: omeprazole; Drug: s-warfarin; Drug: caffeine; Dietary Supplement: vitamin K; Drug: digoxin; Drug: midazolam
Sponsors: Daiichi Sankyo Inc.; Daiichi Sankyo Inc.; Medpace, Inc.
Recruiting - verified January 2012 - Conditions: Chronic Pain; Opioid Abuse, Unspecified Use
Interventions: Behavioral: Mindfulness-Oriented Recovery Enhancement; Behavioral: Conventional Support Group (SG)
Sponsors: Florida State University; Florida State University; National Institute on Drug Abuse (NIDA); Fahs Beck Fund for Research and Experimentation
Recruiting - verified March 2012 - Conditions: Acute Lymphoblastic Leukemia; Neuropathy; Neuropathic Pain
Interventions: Drug: gabapentin; Drug: placebo
Sponsors: St. Jude Children's Research Hospital; St. Jude Children's Research Hospital
Recruiting - verified January 2012 - Conditions: Postoperative Pain; Delirium; Confusion; Sleep
Interventions: Drug: Melatonin; Drug: Placebo
Sponsors: Hospital for Special Surgery, New York; Hospital for Special Surgery, New York
Recruiting - verified March 2012 - Condition: Bipolar Disorder
Interventions: Drug: Ketamine hydrochloride injection; Drug: Flat tonic water (e.g., Canada Dry Tonic Water)
Sponsors: Juvenile Bipolar Research Foundation; Juvenile Bipolar Research Foundation
Not yet recruiting - verified April 2012 - Condition: Cocaine Dependence
Interventions: Drug: Ketamine; Drug: Lorazepam (control)
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2012 - Conditions: Chronic Low Back Pain; Degenerative Disc Disease; Depression; Anxiety
Interventions: Drug: Oxycodone; Drug: Morphine
Sponsors: Brigham and Women's Hospital; Brigham and Women's Hospital; Arthritis Foundation; National Institute on Drug Abuse (NIDA)
Recruiting - verified March 2012 - Condition: Agitation
Interventions: Drug: Haloperidol; Drug: Midazolam
Sponsors: Catholic Health East; Catholic Health East
Recruiting - verified December 2011 - Condition: Acute Stroke
Intervention: Drug: Magnesium Sulfate
Sponsors: University of Southern California; University of Southern California; University of California, Los Angeles
Not yet recruiting - verified December 2011 - Condition: Chronic Pain
Intervention: Behavioral: Therapeutic Education System (TES) for chronic pain
Sponsors: National Development and Research Institutes, Inc.; National Development and Research Institutes, Inc.; National Institute on Drug Abuse (NIDA); Beth Israel Medical Center
Not yet recruiting - verified December 2011 - Conditions: Vulvodynia; Dyspareunia; Breast Cancer; Menopause
Intervention: Drug: Topical liquid lidocaine
Sponsors: Oregon Health and Science University; Oregon Health and Science University
Recruiting - verified February 2012 - Condition: Children Undergoing Anesthesia
Intervention:
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Not yet recruiting - verified December 2011 - Conditions: Tethered Spinal Cord; Brain Tumor; Cranio Cervical Compression
Intervention: Other: Isoflurane, Propofol, Dexmedetomidine
Sponsors: Oregon Health and Science University; Oregon Health and Science University
Recruiting - verified January 2012 - Condition: Transplantation, Kidney
Interventions: Procedure: Transversus abdominis plane (TAP) block; Procedure: Sham TAP block with normal saline
Sponsors: University of California, San Francisco; University of California, San Francisco
Not yet recruiting - verified December 2011 - Condition: Cleft Palate
Interventions: Drug: Oral acetaminophen; Drug: Ofirmev®; Drug: Opioid only
Sponsors: Loma Linda University; Loma Linda University
Recruiting - verified December 2011 - Conditions: Seizures; Epilepsy; Partial Epilepsy; Depression
Intervention: Drug: Buspirone
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified November 2011 - Condition: Schizophrenia
Interventions: Drug: ITI-007; Drug: Placebo; Drug: Risperidone
Sponsors: Intra-Cellular Therapies, Inc.; Intra-Cellular Therapies, Inc.
Recruiting - verified January 2012 - Conditions: Migraine; Migraine Disorders; Headache
Interventions: Drug: Amitriptyline; Drug: Topiramate; Drug: Placebo
Sponsors: Children's Hospital Medical Center, Cincinnati; Children's Hospital Medical Center, Cincinnati; National Institute of Neurological Disorders and Stroke (NINDS)
Not yet recruiting - verified April 2012 - Conditions: Neonatal Neurobehavior; Breastfeeding Outcomes
Interventions: Drug: Bolus 10mL 0.25% bupivacaine/ep 1:600,000; infusion 10mL/hour 0.25% bupivacaine and epi 1:800,000; Drug: Bolus 10mL 0.25% bupivacaine/ epinephrine 1:600,000;infusion 10mL/hour 0.25% bupivacaine, 2 mcg/mL fentanyl, and epinephrine 1:800,000; Drug: Bolus 10mL 0.25% bupivacaine, 10mcg/mL fentanyl, and epi 1:600,000; infusion 10mL/hour 0.25% bupivacaine, 2.5 mcg/mL fentanyl, and epi 1:800,000; Drug: Bolus 10mL 0.25% bupivacaine, 5 mcg/mL fentanyl, and epi 1:600,000; infusion 10mL/hour 0.25% bupivacaine, 3.5 mcg/mL fentanyl, and epi 1:800,000; Drug: No epidural fentanyl or bupivacaine
Sponsors: University Hospital Case Medical Center; University Hospital Case Medical Center
Not yet recruiting - verified April 2012 - Conditions: Sciatica; Radiculopathy
Interventions: Procedure: epidural steroid injection; Procedure: Sham epidural steroid injection; Drug: Gabapentin; Drug: Placebo gabapentin
Sponsors: Johns Hopkins University; Johns Hopkins University; Walter Reed National Military Medical Center; Brooke Army Medical Center; Landstuhl Regional Medical Center; DC VA Hospital; San Diego Naval Hospital; Case Western Reserve University; Penn State-Hershey
Recruiting - verified March 2012 - Condition: Supraventricular Tachycardia
Interventions: Drug: Dexmedetomidine; Drug: Adenosine
Sponsors: University of Pittsburgh; University of Pittsburgh
Recruiting - verified February 2012 - Conditions: Inguinal Hernia; Circumcision
Intervention:
Sponsors: Loma Linda University; Loma Linda University
Not yet recruiting - verified December 2011 - Conditions: Magnetic Resonance Spectroscopy; Ethanol; Spectroscopy
Intervention: Drug: Alcohol
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified November 2011 - Condition: Pain
Interventions: Drug: Bupivacaine; Drug: Saline
Sponsors: Johns Hopkins University; Johns Hopkins University
Not yet recruiting - verified December 2011 - Condition: Healthy
Interventions: Drug: Olanzapine; Drug: Placebo
Sponsors: State University of New York at Buffalo; State University of New York at Buffalo
Recruiting - verified December 2011 - Condition: Duration of Interscalene Block
Interventions: Other: ropivacaine plus dexamethasone anesthetic; Other: ropivacaine plus saline plus dexamethasone anesthetic
Sponsors: The Cleveland Clinic; The Cleveland Clinic
Recruiting - verified December 2011 - Condition: Cocaine Dependence
Intervention: Drug: lisdexamfetamine
Sponsors: University of Minnesota - Clinical and Translational Science Institute; University of Minnesota - Clinical and Translational Science Institute
Recruiting - verified December 2011 - Condition: Addiction
Interventions: Drug: Galantamine; Drug: Placebo
Sponsors: Yale University; Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Conditions: Acute Schizophrenia; Schizoaffective Disorder
Interventions: Drug: RP5063; Drug: placebo; Drug: RP5063; Drug: RP5063; Drug: aripiprazole
Sponsors: Reviva Pharmaceuticals; Reviva Pharmaceuticals
Recruiting - verified December 2011 - Condition: Hepatocellular Carcinoma
Interventions: Drug: Drug-Eluting Beads with Doxorubicin; Drug: Lipiodol ethanol mixture
Sponsors: Masonic Cancer Center, University of Minnesota; Masonic Cancer Center, University of Minnesota
Recruiting - verified March 2012 - Conditions: Maternal Anaesthesia and Analgesia Affecting Fetus or Newborn; Breast Feeding; Fentanyl; Bupivacaine; Nalbuphine
Intervention:
Sponsors: University Hospital Case Medical Center; University Hospital Case Medical Center
Recruiting - verified February 2012 - Conditions: Colon Cancer; Rectal Cancer; Colonic Diverticulosis
Interventions: Drug: Fentanyl; Drug: Propofol; Drug: Midazolam
Sponsors: Saint Joseph Mercy Health System; Saint Joseph Mercy Health System
Recruiting - verified December 2011 - Condition: Cocaine Dependence
Intervention: Drug: Lisdexamfetamine
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute on Drug Abuse (NIDA)
Recruiting - verified May 2012 - Condition: Insomnia
Interventions: Drug: Dexmedetomidine; Drug: Zolpidem; Drug: Oral Placebo; Drug: Normal Saline placebo.
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; National Institutes of Health (NIH)
Recruiting - verified December 2011 - Condition: Dexmedetomidine Induced Sedation
Intervention: Drug: dexmedetomidine
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified April 2012 - Conditions: Overactive Bladder; Overactive Urinary Bladder
Interventions: Drug: MK-4618; Drug: Tolterodine ER; Drug: MK-1468 and Tolterodine ER; Other: Placebo (MK-4618); Other: Placebo (Tolterodine ER); Drug: Prophylactic Antibiotic
Sponsors: Merck; Merck
Recruiting - verified February 2012 - Condition: Pain
Interventions: Drug: Intraperitoneal Ropivacaine (AIR); Other: Atomized Intraperitoneal Saline (AIS)
Sponsors: Loyola University; Loyola University
Recruiting - verified November 2011 - Condition: Post Operative Pain
Interventions: Drug: Group A-Paravertebral block; Other: Group B- No block
Sponsors: Loyola University; Loyola University
Recruiting - verified November 2011 - Conditions: Anemia, Sickle Cell; Pain
Interventions: Drug: Fentanyl Citrate; Drug: Normal Saline
Sponsors: Montefiore Medical Center; hnin khine
Recruiting - verified April 2012 - Condition: Bipolar I Disorder
Intervention: Drug: Lithium/Matching Placebo and an SGA (Second Generation Antipsychotic)
Sponsors: North Shore Long Island Jewish Health System; North Shore Long Island Jewish Health System; National Institutes of Health (NIH)
Recruiting - verified December 2011 - Condition: Osteoarthritis, Knee
Interventions: Device: Ivivi Torino II; Device: Ivivi Torino II
Sponsors: Amp Orthopedics, Inc.; Amp Orthopedics, Inc.
Recruiting - verified November 2011 - Condition: Neonatal Seizures
Intervention:
Sponsors: Children's Hospital Medical Center, Cincinnati; Stephanie Merhar, MD
Recruiting - verified November 2011 - Condition: Central Line-Associated Bloodstream Infection
Interventions: Drug: ethanol; Drug: heparin-saline placebo
Sponsors: St. Jude Children's Research Hospital; St. Jude Children's Research Hospital
Recruiting - verified January 2012 - Condition: Migraine
Interventions: Drug: Ketorolac; Drug: Placebo
Sponsors: Akron Children's Hospital; Akron Children's Hospital
Recruiting - verified February 2012 - Conditions: PONV; Nausea
Interventions: Drug: Aprepitant; Drug: Ondansetron
Sponsors: Ohio State University; Sergio Bergese
Recruiting - verified November 2011 - Condition: Mucinous Pancreatic Cysts
Interventions: Drug: Ethanol; Drug: Normal Saline; Drug: Chemotherapy
Sponsors: Milton S. Hershey Medical Center; Milton S. Hershey Medical Center
Recruiting - verified November 2011 - Condition: Cocaine Dependence
Interventions: Drug: levodopa carbidopa and entacapone (LCE); Drug: Placebo
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute
Not yet recruiting - verified December 2011 - Condition: Interstitial Cystitis
Interventions: Drug: Lidocaine Releasing Intravesical System - LiRIS®; Other: LiRIS Placebo; Procedure: Sham
Sponsors: TARIS Biomedical, Inc.; TARIS Biomedical, Inc.
Recruiting - verified May 2012 - Condition: Postoperative Pain
Intervention: Drug: Morphine
Sponsors: Columbia University; Columbia University
Recruiting - verified February 2012 - Condition: Pain
Intervention: Drug: Paracervical block technique with lidocaine
Sponsors: Oregon Health and Science University; Oregon Health and Science University; Planned Parenthood Federation of America
Recruiting - verified February 2012 - Condition: Insomnia
Interventions: Drug: E2006 1.0 mg; Drug: E2006 2.5 mg; Drug: E2006 5.0 mg; Drug: E2006 10.0 mg; Drug: E2006 25.0 mg; Drug: E2006 50.0 mg; Drug: E2006 100 mg; Drug: E2006 200 mg; Drug: zolpidem 10 mg; Drug: zolpidem - matched placebo; Drug: E2006 - matched placebo
Sponsors: Eisai Inc.; Eisai Inc.
Recruiting - verified April 2012 - Condition: Retraction of Colostomy
Interventions: Drug: IV morphine sulfate; Drug: SKY0402 (bupivacaine liposome injectable suspension)
Sponsors: Pacira Pharmaceuticals, Inc; Pacira Pharmaceuticals, Inc; Registrat-Mapi
Recruiting - verified February 2012 - Condition: Retraction of Colostomy
Interventions: Drug: Morphine Sulfate; Drug: bupivacaine liposome extended-release injectable suspension
Sponsors: Pacira Pharmaceuticals, Inc; Pacira Pharmaceuticals, Inc; Registrat-Mapi
Recruiting - verified February 2012 - Condition: Bowel Obstruction
Interventions: Drug: IV Morphine Sulfate; Drug: SKY0402 (bupivacaine liposome injectable suspension)
Sponsors: Pacira Pharmaceuticals, Inc; Pacira Pharmaceuticals, Inc; Registrat-Mapi
Recruiting - verified April 2012 - Condition: Bowel Obstruction
Interventions: Drug: morphine sulfate; Drug: bupivacaine liposome extended-release injectable suspension
Sponsors: Pacira Pharmaceuticals, Inc; Pacira Pharmaceuticals, Inc; Registrat-Mapi
Recruiting - verified January 2012 - Condition: Bowel Obstruction
Interventions: Drug: IV morphine sulfate; Drug: EXPAREL (bupivacaine liposome injectable suspension)
Sponsors: Pacira Pharmaceuticals, Inc; Pacira Pharmaceuticals, Inc; Registrat-Mapi
Recruiting - verified February 2012 - Condition: BOWEL OBSTRUCTION
Interventions: Drug: Morphine Sulfate; Drug: bupivacaine liposome extended-release injectable suspension
Sponsors: Pacira Pharmaceuticals, Inc; Pacira Pharmaceuticals, Inc; Registrat-Mapi
Recruiting - verified April 2012 - Condition: Bowel Obstruction
Interventions: Drug: Morphine Sulfate; Drug: bupivacaine liposome injectable suspension
Sponsors: Pacira Pharmaceuticals, Inc; Pacira Pharmaceuticals, Inc; Registrat-Mapi
Recruiting - verified April 2012 - Condition: Opioid Induced Constipation
Interventions: Drug: TD-1211; Drug: TD-1211; Drug: TD-1211; Drug: Placebo
Sponsors: Theravance; Theravance
Recruiting - verified November 2011 - Condition: Bowel Obstruction
Interventions: Drug: IV Morphine Sulfate; Drug: SKY0402 (bupivacaine liposome extended-release injectable suspension)
Sponsors: Pacira Pharmaceuticals, Inc; Pacira Pharmaceuticals, Inc; Registrat-Mapi
Recruiting - verified January 2012 - Condition: Cocaine Dependence
Interventions: Drug: Citalopram; Drug: Citalopram; Drug: Placebo
Sponsors: The University of Texas Health Science Center, Houston; Joy Schmitz; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Condition: Bowel Obstruction
Interventions: Drug: IV morphine sulfate; Drug: SKY0402 (bupivacaine liposome extended-release injectable suspension)
Sponsors: Pacira Pharmaceuticals, Inc; Pacira Pharmaceuticals, Inc; Registrat-Mapi
Recruiting - verified January 2012 - Condition: Bipolar Disorder
Intervention: Drug: Asenapine
Sponsors: University Hospitals of Cleveland; University Hospitals of Cleveland; Case Western Reserve University
Recruiting - verified May 2012 - Condition: Bowel Obstruction
Interventions: Drug: IV morphine sulfate; Drug: SKY0402 (bupivacaine liposome injectable suspension)
Sponsors: Pacira Pharmaceuticals, Inc; Pacira Pharmaceuticals, Inc; Registrat-Mapi
Recruiting - verified January 2012 - Condition: Pain, Postoperative
Interventions: Procedure: Proximal placement; Procedure: Short axis ultrasound; Procedure: Long axis; Procedure: Distal placement
Sponsors: VA Palo Alto Health Care System; VA Palo Alto Health Care System
Recruiting - verified October 2011 - Condition: Hallux Valgus
Interventions: Drug: Ropivacaine; Drug: Ropivacaine
Sponsors: Northwestern University; Northwestern University
Recruiting - verified March 2012 - Condition: Pulmonary Embolism
Interventions: Drug: Technegas V/Q SPECT; Drug: Xenon-133
Sponsors: Cyclomedica Australia PTY Limited; Cyclomedica Australia PTY Limited
Not yet recruiting - verified February 2012 - Condition: Lung Cancer
Interventions: Drug: DOTAP:Chol-fus1; Drug: Erlotinib; Drug: Dexamethasone; Drug: Diphenhydramine
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center; Convergen LifeSciences, Inc.
Not yet recruiting - verified March 2012 - Condition: Schizophrenia
Interventions: Drug: Asenapine 10 mg once daily in the evening; Drug: Asenapine 5 mg twice daily
Sponsors: Duke University; Duke University; Merck
Not yet recruiting - verified March 2012 - Condition: Schizophrenia
Interventions: Drug: Paliperidone Palmitate; Drug: Risperidone
Sponsors: University of California, Los Angeles; University of California, Los Angeles; Ortho-McNeil Janssen Scientific Affairs, LLC
Not yet recruiting - verified October 2011 - Condition: Chronic Low Back Pain
Interventions: Drug: Hydrocodone bitartrate q24h film-coated tablets; Drug: Placebo to match hydrocodone bitartrate q24h tablets
Sponsors: Purdue Pharma LP; Purdue Pharma LP
Recruiting - verified May 2012 - Condition: Post Operative Pain
Interventions: Drug: 0.25% bupivicaine will be injected at the study port site; Drug: Saline will be injected at the study port site
Sponsors: Stony Brook University; Stony Brook University
Not yet recruiting - verified October 2011 - Condition: Low Back Pain
Intervention: Drug: Hydromorphone ER
Sponsors: Rehabilitation Institute of Chicago; Rehabilitation Institute of Chicago; Mallinckrodt
Recruiting - verified February 2012 - Condition: Surgical Anesthesia
Intervention: Drug: Ropivacaine concentration
Sponsors: University of New Mexico; University of New Mexico; University of Toronto
Recruiting - verified January 2012 - Condition: Schizophrenia (Recent-onset)
Interventions: Drug: paliperidone palmitate; Drug: risperidone
Sponsors: National Institute of Mental Health (NIMH); National Institute of Mental Health (NIMH); Ortho-McNeil Janssen Scientific Affairs, LLC
Not yet recruiting - verified October 2011 - Conditions: Nausea; Vomiting; Glioma
Interventions: Drug: Aprepitant and Ondansetron; Drug: Ondansetron
Sponsors: Duke University; Duke University; Merck
Not yet recruiting - verified March 2012 - Condition: Interscalene Blockade in Elective Arthroscopic Rotator Cuff Repair
Interventions: Drug: Ropivacaine; Drug: Dexamethasone; Drug: Dexamethasone; Drug: Normal saline; Drug: Normal saline
Sponsors: Mayo Clinic; Mayo Clinic
Recruiting - verified May 2012 - Condition: Pain
Interventions: Procedure: Infiltration of local anesthetic; Procedure: Normal Saline Injection
Sponsors: Saint Francis Care; Saint Francis Care
Recruiting - verified October 2011 - Condition: Postoperative Nausea and Vomiting
Interventions: Drug: general balanced anesthesia; Drug: TIVA NoNarc
Sponsors: Coastal Anesthesiology Consultants; Coastal Anesthesiology Consultants
Recruiting - verified November 2011 - Condition: Fibromyalgia
Interventions: Drug: Quetiapine; Drug: Placebo
Sponsors: East Tennessee State University; East Tennessee State University; AstraZeneca
Recruiting - verified October 2011 - Condition: Neonatal Abstinence Syndrome
Interventions: Drug: sublingual buprenorphine; Drug: oral morphine
Sponsors: Thomas Jefferson University; Thomas Jefferson University; National Institute on Drug Abuse (NIDA)
Recruiting - verified November 2011 - Conditions: Gynecologic Cancer; Post-operative Pain
Interventions: Drug: Bupivicaine; Drug: Placebo
Sponsors: University of Wisconsin, Madison; University of Wisconsin, Madison
Recruiting - verified September 2011 - Conditions: Hepatitis C; Medication Adherence
Interventions: Other: enhanced DOT (both pegylated interferon alfa-2a and ribavirin); Other: standard DOT (PEG-DOT control arm)
Sponsors: Albert Einstein College of Medicine of Yeshiva University; Albert Einstein College of Medicine of Yeshiva University; National Institute on Drug Abuse (NIDA)
Recruiting - verified September 2011 - Condition: Healthy Male Volunteer
Interventions: Drug: JNJ-38518168 (30 mg); Drug: JNJ-38518168 (10 mg); Drug: JNJ-38518168 (3 mg); Drug: Placebo; Drug: Midazolam and JNJ-38518168
Sponsors: Janssen Research & Development, LLC; Janssen Research & Development, LLC
Recruiting - verified April 2012 - Condition: Pain
Interventions: Drug: 150% Oral Morphine Equivalent (OME); Other: Clinical Judgment
Sponsors: Abbott Northwestern Hospital; Abbott Northwestern Hospital; Allina Hospitals and Clinics
Recruiting - verified October 2011 - Conditions: Anesthesia; Neuromuscular Blockade
Interventions: Drug: Remifentanil infusion; Drug: Rocuronium dose + Remifentanil infusion; Drug: Rocuronium dose + Remifentanil infusion; Drug: Rocuronium dose + Remifentanil infusion; Drug: Remifentanil infusion; Drug: Rocuronium dose + Remifentanil infusion; Drug: Rocuronium dose + Remifentanil infusion; Drug: Rocuronium dose + Remifentanil infusion
Sponsors: Covidien; Covidien
Recruiting - verified May 2012 - Condition: Chemotherapy-Induced Nausea and Vomiting
Interventions: Drug: Palonosetron; Drug: Palonosetron; Drug: Ondansetron
Sponsors: Helsinn Healthcare SA; Helsinn Healthcare SA
Recruiting - verified May 2012 - Conditions: Tourniquet-induced Pain; Tourniquet-induced Hypertension
Interventions: Drug: gabapentin 600 mg po; Drug: Placebo pill given one hour before surgery
Sponsors: Baylor College of Medicine; Baylor College of Medicine
Not yet recruiting - verified September 2011 - Condition: Opioid Induced Constipation
Interventions: Drug: Placebo once daily; Drug: 0.1 mg of S-297995 once daily; Drug: 0.2 mg of S-297995 once daily; Drug: 0.4 mg of S-297995 once daily
Sponsors: Shionogi Inc.; Shionogi
Recruiting - verified October 2011 - Conditions: Surgery; Pain
Interventions: Drug: .9 normal saline; Drug: 25 mg diphenhydramine IV; Drug: 50 mg diphenhydramine IV
Sponsors: Northwestern University; Northwestern University
Recruiting - verified February 2012 - Condition: Surgical Site Infections
Interventions: Drug: Iodine-alcohol; Drug: Chlorhexidine-alcohol
Sponsors: Washington University School of Medicine; Washington University School of Medicine
Recruiting - verified November 2011 - Condition: Neoplasms
Interventions: Drug: Gemcitabine; Drug: BAY80-6946; Drug: Cisplatin; Drug: NaCl; Drug: BAY80-6964 fixed dose
Sponsors: Bayer; Bayer
Recruiting - verified May 2012 - Condition: Schizophrenia
Intervention: Drug: Aripiprazole (Abilify®) IM Depot Injection
Sponsors: Otsuka Pharmaceutical Development & Commercialization, Inc.; Otsuka Pharmaceutical Development & Commercialization, Inc.
Recruiting - verified November 2011 - Conditions: Pain; Opioid Use, Unspecified, Uncomplicated
Interventions: Drug: Placebo infusion of .9 normal saline; Drug: administration of magnesium sulfate
Sponsors: Northwestern University; Northwestern University
Recruiting - verified February 2012 - Condition: Hypoventilation
Interventions: Drug: Placebo; Drug: Ketamine infusion
Sponsors: Northwestern University; Northwestern University
Recruiting - verified May 2012 - Condition: Opiate Dependence
Interventions: Other: Patient-Centered Methadone Treatment; Other: Methadone Treatment as usual
Sponsors: Friends Research Institute, Inc.; Friends Research Institute, Inc.
Recruiting - verified September 2011 - Conditions: Mediastinal Lymphadenopathies; Mediastinal Masses; Hilar Lymphadenopathies
Intervention:
Sponsors: Baylor College of Medicine; Baylor College of Medicine
Recruiting - verified October 2011 - Condition: Bipolar Disorder I or II
Intervention: Drug: Tranylcypromine
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute
Recruiting - verified September 2011 - Condition: Pain
Interventions: Drug: Hydromorphone; Drug: Usual care
Sponsors: Montefiore Medical Center; Montefiore Medical Center
Recruiting - verified September 2011 - Condition: Low Back Pain
Interventions: Drug: Oxycodone/Naloxone controlled-release; Drug: Oxycodone HCl controlled-release; Drug: Placebo
Sponsors: Purdue Pharma LP; Purdue Pharma LP
Recruiting - verified May 2012 - Condition: Low Back Pain
Interventions: Drug: Oxycodone/Naloxone controlled-release; Drug: Oxycodone HCl controlled-release; Drug: Placebo
Sponsors: Purdue Pharma LP; Purdue Pharma LP
Recruiting - verified May 2012 - Condition: Psychotic Depression
Interventions: Drug: Olanzapine; Drug: Placebo
Sponsors: Weill Medical College of Cornell University; Weill Medical College of Cornell University; University of Toronto; University of Massachusetts, Worcester; University of Pittsburgh
Recruiting - verified March 2012 - Condition: Pain
Intervention: Other: Drug Dose
Sponsors: Stanford University; Stanford University
Recruiting - verified August 2011 - Conditions: Contraceptive Usage; Opioid Dependence
Interventions: Behavioral: Contraceptive management program; Other: Usual care
Sponsors: University of Vermont; University of Vermont
Recruiting - verified December 2011 - Condition: Primary Hypomagnesemia (Disorder)
Intervention: Drug: Magnesium Sulfate
Sponsors: CAMC Health System; CAMC Health System; Sara and Pauline Maier Foundation, Inc.
Recruiting - verified December 2011 - Condition: Pain
Interventions: Drug: Lidocaine; Drug: Placebo
Sponsors: University of Wisconsin, Madison; University of Wisconsin, Madison
Recruiting - verified September 2011 - Conditions: Schizophrenia; Schizoaffective Disorder
Interventions: Behavioral: Visual Decision Aid and Shared Decision Making Model; Behavioral: Usual Care
Sponsors: VA Nebraska Western Iowa Health Care System; VA Nebraska Western Iowa Health Care System; New England MIRECC; Nebraska Educational Biomedical Research Association
Recruiting - verified August 2011 - Condition: Insomnia
Intervention: Drug: Gabapentin
Sponsors: University at Buffalo; University at Buffalo
Recruiting - verified August 2011 - Condition: Type 1 Diabetes Mellitus
Interventions: Drug: Closed loop with pramlintide; Device: Closed loop without pramlintide; Drug: Open loop with pramlintide
Sponsors: University of Virginia; University of Virginia; The Paul Manning Foundation (private)
Recruiting - verified September 2011 - Conditions: Major Depressive Disorder; Bipolar Disorder
Interventions: Behavioral: Wake Therapy; Device: lightbox; Drug: Lithium Carbonate; Drug: Armodafinil
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute
Recruiting - verified April 2012 - Condition: Epilepsy
Intervention: Drug: Diazepam
Sponsors: Neuronex, Inc.; Neuronex, Inc.
Recruiting - verified November 2011 - Condition: Opiate Dependence
Intervention: Behavioral: employment based reinforcement
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2010 - Condition: Constipation
Interventions: Other: Opioid Dose Intervention; Other: Opioid Assessment Intervention; Other: Vinca Alkaloid Assessment Intervention
Sponsors: H. Lee Moffitt Cancer Center and Research Institute; H. Lee Moffitt Cancer Center and Research Institute; National Institutes of Health (NIH); University of South Florida
Recruiting - verified January 2012 - Condition: Major Depressive Disorder
Interventions: Drug: Augmenting: Antidepressant + Aripiprazole; Drug: Augmenting: Antidepressant + Bupropion-SR; Drug: Switching: Bupropion-SR
Sponsors: Department of Veterans Affairs; Department of Veterans Affairs
Not yet recruiting - verified March 2012 - Conditions: Pain; Intrauterine Device
Interventions: Drug: 2% lidocaine gel; Drug: Water based lubricant
Sponsors: Washington University School of Medicine; Washington University School of Medicine
Recruiting - verified August 2011 - Condition: Value of the Bowel Preparation Versus Diet Change
Interventions: Other: No bowel prep; Other: Clear liquid diet and 2 Fleet's enemas
Sponsors: University of Alabama at Birmingham; University of Alabama at Birmingham
Recruiting - verified April 2012 - Condition: Postop Adult ICU Patients
Intervention: Procedure: Provide Music to Adult Postop Patients in the ICU.
Sponsors: National Institutes of Health Clinical Center (CC); National Institutes of Health Clinical Center (CC)
Recruiting - verified March 2012 - Condition: Healthy
Interventions: Drug: Ecopipam immediate release form; Drug: 90 mg controlled release form; Drug: 180 mg controlled release form
Sponsors: Psyadon Pharma; Psyadon Pharma
Recruiting - verified August 2011 - Condition: Tourette's Disorder
Intervention: Drug: aripiprazole
Sponsors: Otsuka Pharmaceutical Development & Commercialization, Inc.; Otsuka Pharmaceutical Development & Commercialization, Inc.
Recruiting - verified January 2012 - Condition: Tourette's Disorder
Intervention: Drug: aripiprazole
Sponsors: Otsuka Pharmaceutical Development & Commercialization, Inc.; Otsuka Pharmaceutical Development & Commercialization, Inc.
Recruiting - verified January 2012 - Condition: Tourette's Disorder
Intervention: Drug: aripiprazole
Sponsors: Otsuka Pharmaceutical Development & Commercialization, Inc.; Otsuka Pharmaceutical Development & Commercialization, Inc.
Recruiting - verified April 2012 - Conditions: Depression; Depressive Disorder; Depressive Disorder, Major
Interventions: Drug: Buprenorphine; Drug: Placebo
Sponsors: University of Pittsburgh; University of Pittsburgh; National Alliance for Research on Schizophrenia and Depression
Recruiting - verified January 2012 - Condition: Uterine Cervical Dysplasia
Intervention: Drug: sodium bicarbonate buffered lidocaine
Sponsors: Washington University School of Medicine; Washington University School of Medicine
Recruiting - verified October 2011 - Condition: Cocaine Dependence
Interventions: Drug: Oral tacrine; Drug: Oral placebo
Sponsors: Midwest Biomedical Research Foundation; Midwest Biomedical Research Foundation
Not yet recruiting - verified May 2012 - Condition: Cocaine Dependence
Interventions: Drug: Buprenorphine + Naltrexone; Drug: Placebo + Naltrexone
Sponsors: University of California, Los Angeles; Walter Ling; National Institute on Drug Abuse (NIDA); The EMMES Corporation
Recruiting - verified February 2012 - Condition: Analgesia After ED Discharge for Extremity Injuries
Intervention: Drug: Oral Opioid Pain Medicine
Sponsors: Montefiore Medical Center; Montefiore Medical Center
Recruiting - verified December 2011 - Condition: Cocaine Abuse
Intervention: Behavioral: prize contingency management
Sponsors: University of Connecticut Health Center; University of Connecticut Health Center; National Institute on Drug Abuse (NIDA)
Recruiting - verified November 2011 - Condition: Schizophrenia
Interventions: Drug: Minocycline; Drug: Placebo
Sponsors: University of Maryland; University of Maryland; National Institute of Mental Health (NIMH)
Recruiting - verified March 2012 - Condition: Chronic Nonmalignant and Nonneuropathic Pain
Intervention: Drug: Hydrocodone bitartrate q24h film-coated tablets
Sponsors: Purdue Pharma LP; Purdue Pharma LP
Recruiting - verified April 2012 - Condition: Opioid Induced Constipation
Intervention: Drug: TD-1211
Sponsors: Theravance; Theravance
Recruiting - verified October 2011 - Condition: Agitation
Interventions: Drug: Asenapine; Drug: Placebo
Sponsors: St. Joseph Hospital Health Center; St. Joseph Hospital Health Center; Schering-Plough
Recruiting - verified April 2012 - Condition: Postoperative Nausea and Vomiting
Interventions: Drug: Palonosetron; Drug: Ondansetron
Sponsors: Helsinn Healthcare SA; Helsinn Healthcare SA
Recruiting - verified January 2012 - Condition: Bipolar I Disorder
Interventions: Drug: asenapine; Drug: asenapine
Sponsors: Schering-Plough; Schering-Plough
Recruiting - verified May 2012 - Condition: Bipolar 1 Disorder
Interventions: Drug: asenapine; Drug: placebo
Sponsors: Schering-Plough; Schering-Plough
Recruiting - verified May 2012 - Double-blind Trial of Buspirone for the Treatment of Anxiety in Youth With Autism Spectrum DisordersCondition: Autism Spectrum Disorder (ASD)
Interventions: Drug: Buspirone; Drug: Placebo
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified February 2012 - Conditions: Heroin Dependence; Nicotine Dependence
Interventions: Drug: Pioglitazone; Drug: Placebo
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute on Drug Abuse (NIDA); Omeros Corporation
Recruiting - verified July 2011 - Condition: Opioid Abuse
Intervention: Drug: pioglitazone
Sponsors: Columbia University; Columbia University; Omeros Corporation
Recruiting - verified July 2011 - Conditions: Postoperative Nausea and Vomiting; Genetic Polymorphisms
Interventions: Drug: Ondansetron; Drug: Lorazepam; Drug: Aprepitant
Sponsors: University of California, San Francisco; University of California, San Francisco; National Cancer Institute (NCI)
Not yet recruiting - verified February 2012 - Condition: Cocaine Dependence
Interventions: Drug: levodopa/carbidopa; Drug: Ropinirole; Drug: Placebo
Sponsors: The University of Texas Health Science Center, Houston; The University of Texas Health Science Center, Houston
Recruiting - verified February 2012 - Condition: Alcohol Abuse
Intervention: Behavioral: Group Brief Alcohol Intervention
Sponsors: University of Tennessee; University of Tennessee; National Cancer Institute (NCI); University of Minnesota - Clinical and Translational Science Institute; United States Air Force
Recruiting - verified July 2011 - Condition: Cardiac Arrest
Interventions: Drug: amiodarone; Drug: Lidocaine; Other: Normal saline
Sponsors: University of Washington; University of Washington; National Heart, Lung, and Blood Institute (NHLBI); Canadian Institutes of Health Research (CIHR); Heart and Stroke Foundation of Canada; American Heart Association; Defence Research and Development Canada; U.S. Army Medical Research and Materiel Command
Not yet recruiting - verified February 2012 - Condition: Kidney Cancer
Interventions: Drug: Pazopanib; Drug: Temsirolimus; Behavioral: Quality of Life Assessment; Drug: Benadryl
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center; GlaxoSmithKline
Not yet recruiting - verified March 2012 - Condition: Airway Remodeling
Interventions: Drug: Dexmedetomidine; Drug: propofol
Sponsors: Milton S. Hershey Medical Center; Milton S. Hershey Medical Center
Not yet recruiting - verified January 2012 - Conditions: Obesity; Phentermine Withdrawal
Intervention: Drug: Abrupt cessation of phentermine pharmacotherapy
Sponsors: Center for Weight Management, California; Center for Weight Management, California; American Society of Bariatric Physicians
Recruiting - verified August 2011 - Condition: Opioid-Induced Constipation (OIC)
Interventions: Drug: NKTR-118; Drug: NKTR-118; Drug: Placebo
Sponsors: AstraZeneca; AstraZeneca
Recruiting - verified January 2012 - Conditions: Nicotine Dependence; Opiate Dependence
Interventions: Behavioral: Intensive, tailored intervention; Behavioral: NJ Quitline Referral
Sponsors: University of Medicine and Dentistry New Jersey; University of Medicine and Dentistry New Jersey; National Institute on Drug Abuse (NIDA)
Recruiting - verified January 2012 - Condition: Secretion Removal Above ETT Cuff
Intervention: Drug: methylene blue
Sponsors: Thomas Jefferson University; Thomas Jefferson University; Teleflex
Not yet recruiting - verified July 2011 - Condition: Pain, Postoperative
Interventions: Drug: control group; Drug: treatment group
Sponsors: Children's Hospital of Pittsburgh; Children's Hospital of Pittsburgh
Recruiting - verified June 2011 - Conditions: Pain; Sickle Cell Disease
Interventions: Drug: Morphine; Drug: Nubain
Sponsors: Children's Healthcare of Atlanta; Children's Healthcare of Atlanta; Atlanta Clinical and Translational Science Institute
Recruiting - verified September 2009 - Conditions: Human Immunodeficiency Virus; Acquired Immunodeficiency Syndrome; Opiate Addiction; Drug Dependence
Intervention: Drug: Buprenorphine/naloxone
Sponsors: Yale University; Yale University; George Mason University; Howard University
Recruiting - verified April 2012 - Conditions: Tobacco Use Disorder; Medication Adherence
Intervention: Behavioral: Varenicline treatment as usual or directly observed therapy
Sponsors: Albert Einstein College of Medicine of Yeshiva University; Albert Einstein College of Medicine of Yeshiva University; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Condition: Opioid Dependence
Interventions: Drug: Opioid detoxification using buprenorphine vs. oral naltrexone; Drug: Buprenorphine
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute
Recruiting - verified June 2011 - Condition: Inflammatory Response
Interventions: Drug: Ibuprofen; Drug: Placebo/Saline solution
Sponsors: New York University School of Medicine; New York University School of Medicine
Recruiting - verified June 2011 - Conditions: Complication of Injection; Pain
Interventions: Drug: Fospropofol; Drug: Propofol/Lidocaine
Sponsors: New York University School of Medicine; New York University School of Medicine; Eisai Inc.
Recruiting - verified November 2011 - Condition: Nerve Block
Interventions: Procedure: Local Anesthetic given via perineural catheter for infraclavicular nerve block.; Procedure: Local Anesthetic given via needle for infraclavicular nerve block
Sponsors: University of California, San Diego; University of California, San Diego
Not yet recruiting - verified March 2012 - Condition: Duration of Hospitalization
Interventions: Drug: Isoflurane; Drug: Sevoflurane
Sponsors: Outcomes Research Consortium; Outcomes Research Consortium
Recruiting - verified October 2011 - Conditions: Schizophrenia; Alcoholism; Dual Diagnosis
Interventions: Drug: Risperidone + Desipramine; Drug: Risperidone + Placebo
Sponsors: Dartmouth-Hitchcock Medical Center; Dartmouth-Hitchcock Medical Center; University of South Carolina
Recruiting - verified December 2011 - Conditions: Alpha-1-antitrypsin Deficiency; Liver Cirrhosis
Interventions: Drug: Drug-Carbamazepine (Tegretol XR); Drug: Carbamazepine (Tegretol XR) Placebo
Sponsors: University of Pittsburgh; University of Pittsburgh; Novartis; National Institutes of Health (NIH); National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Not yet recruiting - verified January 2012 - Condition: Pain
Interventions: Drug: 2% lidocaine gel; Drug: 0.5% tetracaine drops
Sponsors: University of Miami; University of Miami
Recruiting - verified October 2010 - Conditions: Bipolar Affective Disorders; Cyclothymic Disorder; Schizoaffective Disorder; Major Depressive Disorder; Dysthymic Disorder; Obsessive-Compulsive Disorder; Panic Disorder; Posttraumatic Stress Disorder; Premenstrual Dysphoric Disorder; Social Anxiety Disorder
Intervention:
Sponsors: Weill Medical College of Cornell University; Weill Medical College of Cornell University
Recruiting - verified June 2011 - Condition: Opioid Use During Medical Care
Intervention:
Sponsors: Albany Medical College; Albany Medical College
Recruiting - verified June 2011 - Condition: Chemotherapy-induced Nausea and Vomiting
Intervention: Drug: Palonosetron, ondansetron, dexamethasone
Sponsors: Northside Hospital, Inc.; Northside Hospital, Inc.; Blood and Marrow Transplant Group of Georgia
Recruiting - verified March 2012 - Condition: Pain
Intervention: Drug: Oxycodone hydrochloride controlled-release tablets
Sponsors: Purdue Pharma LP; Purdue Pharma LP
Recruiting - verified May 2012 - Condition: Obsessive Compulsive Disorder
Interventions: Drug: Ketamine; Drug: Midazolam
Sponsors: Goodman, Wayne, M.D.; Goodman, Wayne, M.D.
Not yet recruiting - verified June 2011 - Conditions: Pain; Anxiety
Interventions: Device: Buzzy; Drug: Topical Lidocaine 4% Cream
Sponsors: Children's Hospital of Philadelphia; Children's Hospital of Philadelphia
Recruiting - verified May 2012 - Conditions: Chronic Pain; Opioid Dependence
Interventions: Drug: Varenicline; Drug: Placebo
Sponsors: Mayo Clinic; Mayo Clinic
Recruiting - verified May 2012 - Condition: Intubation; Difficult
Intervention: Drug: Midazolam
Sponsors: University of Vermont; University of Vermont
Recruiting - verified May 2011 - Condition: Osteoarthritis of the Knee
Interventions: Drug: ARRY-371797, p38 inhibitor; oral; Drug: Oxycodone hydrochloride (HCl) extended release (ER), opioid agonist; oral; Drug: Placebo; oral
Sponsors: Array BioPharma; Array BioPharma
Recruiting - verified March 2012 - Condition: Bipolar Disorder
Intervention: Drug: Lithium, valproate, lamotrigine
Sponsors: Emory University; Emory University
Recruiting - verified October 2011 - Conditions: Substance Related Disorders; Drug Addiction; Substance Abuse
Interventions: Behavioral: Cash CM; Behavioral: Voucher CM; Behavioral: Non-CM Control
Sponsors: Treatment Research Institute; Treatment Research Institute; National Institute on Drug Abuse (NIDA)
Recruiting - verified July 2011 - Condition: Depression
Interventions: Drug: Ketamine; Drug: methohexital
Sponsors: Mayo Clinic; Mayo Clinic
Recruiting - verified March 2012 - Safety and Efficacy Study of Ethanol Locking to Prevent Central Line Infection in Premature NeonatesConditions: Infection Associated With Catheter; Bacteremia; Sepsis
Interventions: Drug: Ethanol lock; Drug: Heparinized saline
Sponsors: East Carolina University; East Carolina University
Recruiting - verified November 2010 - Condition: Pain
Interventions: Drug: Preservative free morphine; Drug: Fentanyl
Sponsors: Goodman, Evan, M.D.; Goodman, Evan, M.D.
Recruiting - verified May 2011 - Conditions: Pain; Advanced Cancer
Interventions: Drug: Sativex®; Drug: Placebo (GA-0034)
Sponsors: GW Pharmaceuticals Ltd.; GW Pharmaceuticals Ltd.; Otsuka Pharmaceutical Development & Commercialization, Inc.
Recruiting - verified August 2011 - Condition: Impulsive Aggression Comorbid With ADHD
Interventions: Drug: Molindone; Drug: Placebo
Sponsors: Supernus Pharmaceuticals, Inc.; Supernus Pharmaceuticals, Inc.
Recruiting - verified August 2011 - Condition: Osteoarthritis
Intervention: Procedure: Lumbar Plexus Block
Sponsors: Milton S. Hershey Medical Center; Milton S. Hershey Medical Center
Not yet recruiting - verified April 2012 - Condition: Chronic Pain
Intervention: Drug: Ketamine
Sponsors: University of Rochester; University of Rochester
Recruiting - verified May 2011 - Condition: Low Back Pain
Interventions: Drug: Oxycodone/Naloxone Controlled-release; Drug: Placebo
Sponsors: Purdue Pharma LP; Purdue Pharma LP
Recruiting - verified February 2012 - Conditions: Cognitive Deficits; Cognitive Ability, General
Intervention:
Sponsors: University of California, San Francisco; University of California, San Francisco; University of California, Davis
Recruiting - verified January 2012 - Condition: Conscious Sedation
Interventions: Drug: Ketamine; Drug: Ketamine Co-administered with Propofol
Sponsors: Children's Hospital Colorad; Children's Hospital Colorad; Colorado Clinical & Translational Sciences Institute
Recruiting - verified December 2011 - Condition: Schizophrenia
Interventions: Drug: LY2140023; Drug: Aripiprazole
Sponsors: Eli Lilly and Company; Eli Lilly and Company
Recruiting - verified March 2012 - Conditions: Alcohol Consumption; Unsafe Sex
Interventions: Behavioral: Brief Motivational Intervention (BMI); Behavioral: Brief Advice
Sponsors: Brown University; Brown University; National Institute on Alcohol Abuse and Alcoholism (NIAAA); Memorial Hospital of Rhode Island; Kent Hospital
Recruiting - verified November 2011 - Condition: Bipolar Disorder
Intervention: Drug: Asenapine
Sponsors: Schering-Plough; Schering-Plough
Recruiting - verified May 2012 - Conditions: Cannabis Dependence; Marijuana Dependence
Interventions: Drug: Nabilone; Drug: Placebo
Sponsors: Mclean Hospital; Mclean Hospital; National Institute on Drug Abuse (NIDA)
Recruiting - verified January 2012 - Condition: Alcohol Dependence
Interventions: Drug: Valproate; Drug: Naltrexone
Sponsors: Department of Veterans Affairs; Department of Veterans Affairs
Recruiting - verified March 2012 - Conditions: Sacroiliac Joint Pain; Sympathetically Maintained Pain
Interventions: Procedure: sacroiliac joint injection; Procedure: Sympathetic block; Drug: bupivacaine; Drug: corticosteroid
Sponsors: Johns Hopkins University; Johns Hopkins University
Recruiting - verified April 2011 - Condition: PTSD
Interventions: Drug: Ganaxolone; Drug: Placebo
Sponsors: Marinus Pharmaceuticals; Marinus Pharmaceuticals; INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium; U.S. Army Medical Research and Materiel Command
Recruiting - verified April 2012 - Condition: Anorexia Nervosa
Intervention:
Sponsors: National Institute of Mental Health (NIMH); National Institute of Mental Health (NIMH)
Recruiting - verified December 2010 - Conditions: Chronic Pain; Opiate Dependence
Interventions: Behavioral: Cognitive-Behavioral Therapy for Pain and Opioid Dependence; Behavioral: Methadone Drug Counseling
Sponsors: Yale University; Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified May 2012 - Condition: Chronic Rhinitis
Interventions: Drug: Placebo; Drug: Guaifenesin
Sponsors: Virginia Commonwealth University; Virginia Commonwealth University; Pfizer
Recruiting - verified May 2011 - Condition: Traumatic Brain Injury
Interventions: Device: Arctic Sun; Drug: Magnesium Sulfate
Sponsors: Department of Defense; Department of Defense
Recruiting - verified December 2011 - Condition: Bipolar Disorder
Interventions: Drug: Lithium; Drug: Quetiapine
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; Agency for Healthcare Research and Quality (AHRQ)
Recruiting - verified April 2012 - Conditions: Hazardous Drinking; HIV
Intervention: Behavioral: Brief alcohol intervention
Sponsors: Brown University; Brown University
Recruiting - verified October 2011 - Conditions: Premature Birth of Newborn; Critically Ill
Interventions: Drug: Methadone; Drug: Methadone
Sponsors: Children's Research Institute; Children's Research Institute
Recruiting - verified April 2012 - Condition: Opioid-induced Constipation (OIC)
Interventions: Drug: TD-1211; Drug: Placebo
Sponsors: Theravance; Theravance
Recruiting - verified February 2012 - Condition: Pain
Interventions: Drug: Fentanyl; Drug: Fentanyl
Sponsors: Johns Hopkins University; Johns Hopkins University
Recruiting - verified April 2012 - Condition: Opioid-Induced Constipation (OIC)
Interventions: Drug: NKTR-118; Drug: NKTR-118; Drug: Placebo
Sponsors: AstraZeneca; AstraZeneca
Recruiting - verified January 2012 - Condition: Pain
Intervention: Drug: Buprenorphine transdermal system
Sponsors: Purdue Pharma LP; Purdue Pharma LP
Recruiting - verified December 2011 - Conditions: Temporomandibular Disorder; Facial Pain
Interventions: Drug: Naltrexone; Drug: Placebo
Sponsors: University of Florida; University of Florida; American Pain Society
Recruiting - verified March 2011 - Conditions: Mechanically Ventilated Neonates,; Painful Procedures in Newborns
Intervention: Drug: Codeine
Sponsors: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - verified February 2012 - Condition: Acute Kidney Injury
Interventions: Drug: ATG; Drug: Rituximab; Drug: Methylprednisolone; Drug: Diphenhydramine; Drug: Acetaminophen; Drug: Tacrolimus; Drug: Sirolimus; Drug: Hydrocortisone; Drug: Prednisone
Sponsors: National Institute of Allergy and Infectious Diseases (NIAID); National Institute of Allergy and Infectious Diseases (NIAID); Immune Tolerance Network (ITN)
Recruiting - verified August 2011 - Condition: Epilepsy
Intervention: Drug: intranasal midazolam hydrochloride
Sponsors: Columbia University; Columbia University
Recruiting - verified January 2012 - Condition: Major Depressive Disorder
Interventions: Drug: PNB01 fixed dose combination of pipamperone and citalopram; Drug: Citalopram; Drug: Pipamperone
Sponsors: PharmaNeuroBoost N.V.; PharmaNeuroBoost N.V.
Recruiting - verified March 2012 - Conditions: Ureteral Stent Occlusion; Exposure Laser; Ureterostomy; Functional Disturbance; Vaginal Diseases; Injury of Bladder; Excessive Repair; Calculi
Intervention:
Sponsors: Hahnemann University Hospital; Hahnemann University Hospital; Baxter Healthcare Corporation
Recruiting - verified March 2011 - Condition: Acute Pain
Interventions: Drug: H2O; Drug: 1+1
Sponsors: Montefiore Medical Center; Montefiore Medical Center
Recruiting - verified March 2011 - Conditions: Idiopathic Scoliosis; Spondylolisthesis
Interventions: Drug: Ketamine; Drug: Normal Saline
Sponsors: Children's Research Institute; Children's Research Institute
Recruiting - verified March 2012 - Condition: Major Depressive Disorder
Interventions: Drug: Ketamine; Drug: placebo
Sponsors: Mount Sinai School of Medicine; James Murrough
Recruiting - verified December 2011 - Condition: Local Anesthetics
Interventions: Drug: Lidocaine; Drug: normal saline; Drug: alkalinized lidocaine
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified December 2011 - Condition: Post-operative Pain
Interventions: Drug: Bupivacaine / Lidocaine; Drug: Lidocaine
Sponsors: Baylor Research Institute; Baylor Research Institute
Recruiting - verified February 2012 - Condition: Urinary Bladder, Overactive
Interventions: Drug: MK-4618 low-dose; Drug: MK-4618 mid-low dose; Drug: MK-4618 mid-high dose; Drug: tolterodine ER; Drug: Placebo for MK-4618; Drug: Placebo for tolterodine ER; Drug: MK-4618 high dose
Sponsors: Merck; Merck
Recruiting - verified May 2012 - Condition: Hot Flashes
Interventions: Behavioral: Hypnosis; Behavioral: Structured Attention
Sponsors: Baylor University; Baylor University; National Center for Complementary and Alternative Medicine (NCCAM)
Recruiting - verified February 2012 - Condition: Alcohol Dependence
Interventions: Drug: Aripiprazole; Drug: Placebo
Sponsors: Medical University of South Carolina; Medical University of South Carolina; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified April 2012 - Condition: Schizophrenia
Interventions: Drug: Iloperidone; Drug: Flexible dose Iloperidone including Placebo
Sponsors: Novartis; Novartis Pharmaceuticals
Recruiting - verified April 2012 - Condition: Alcohol or Other Drugs Effects
Interventions: Drug: Alcohol + Caffeine Beverage; Drug: Alcohol + Caffeine-placebo
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute on Drug Abuse (NIDA)
Recruiting - verified January 2011 - Condition: Overactive Bladder
Interventions: Drug: Tolterodine ER; Drug: Placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Conditions: Migraine; Pain
Intervention: Drug: Nitrous Oxide
Sponsors: Children's Hospitals and Clinics of Minnesota; Children's Hospitals and Clinics of Minnesota
Recruiting - verified January 2012 - Condition: Obsessive-compulsive Disorder
Interventions: Drug: Ondansetron; Drug: Placebo
Sponsors: Transcept Pharmaceuticals; Transcept Pharmaceuticals
Recruiting - verified March 2012 - Condition: The Duration of Motor Block for Sciatic Block Following TKR May Vary Between 12-36 Hrs Depending on the Amount of Local Anesthetic Given.
Interventions: Drug: Bupivacaine; Drug: Ropivacaine
Sponsors: Northwestern University; Northwestern University
Recruiting - verified March 2012 - Condition: Bipolar Affective Disorder
Intervention: Drug: Mood stabilizer treatment
Sponsors: University of California, San Diego; University of California, San Diego
Recruiting - verified April 2012 - Condition: Obesity
Interventions: Dietary Supplement: IHBG-10; Dietary Supplement: Placebo
Sponsors: Avera McKennan Hospital & University Health Center; Avera McKennan Hospital & University Health Center
Not yet recruiting - verified January 2011 - Condition: Obesity
Interventions: Other: Placebo; Dietary Supplement: IHBG-10
Sponsors: Avera McKennan Hospital & University Health Center; Avera McKennan Hospital & University Health Center
Not yet recruiting - verified January 2011 - Condition: Pain
Interventions: Drug: Fentanyl; Drug: Fentanyl; Drug: Oxycodone/acetaminophen; Drug: oxycodone/acetaminophen
Sponsors: University of Oklahoma; Stephen Thomas; University of Oklahoma
Recruiting - verified February 2012 - Conditions: Spinal Stenosis; Inflammation
Intervention:
Sponsors: New York University School of Medicine; New York University School of Medicine; Hospira, Inc.
Recruiting - verified April 2012 - Conditions: Laceration; Pain
Interventions: Drug: Ibuprofen; Drug: Oxycodone; Other: Placebo
Sponsors: Children's Hospitals and Clinics of Minnesota; Children's Hospitals and Clinics of Minnesota
Not yet recruiting - verified November 2011 - Condition: Cocaine Dependence
Intervention: Drug: Buspirone
Sponsors: The University of Texas Health Science Center, Houston; The University of Texas Health Science Center, Houston
Recruiting - verified March 2012 - Conditions: Tonsillitis; Pain
Interventions: Drug: Codeine with acetaminophen; Drug: Tramadol suspension
Sponsors: Children's Hospitals and Clinics of Minnesota; Children's Hospitals and Clinics of Minnesota
Recruiting - verified September 2011 - Conditions: Adult Intracranial Tumor; Adult Solid Tumor
Interventions: Drug: Remifentanil; Drug: Dexmedetomidine
Sponsors: Outcomes Research Consortium; Outcomes Research Consortium
Recruiting - verified August 2011 - Condition: Acute Migraine
Interventions: Drug: Metoclorpamide; Drug: Ketorolac; Drug: Valproate
Sponsors: Montefiore Medical Center; Montefiore Medical Center
Recruiting - verified April 2012 - Conditions: Obesity; Arthritis
Intervention: Drug: propofol or desflurane
Sponsors: Stanford University; Stanford University; Baxter Healthcare Corporation
Recruiting - verified July 2011 - Condition: Procedural Sedation
Interventions: Drug: Propofol; Drug: 1:1 Propofol/Ketamine; Drug: 4:1 Propofol/Ketamine
Sponsors: Minneapolis Medical Research Foundation; Minneapolis Medical Research Foundation
Recruiting - verified May 2012 - Condition: Sedation
Interventions: Procedure: 1:1 ketamine-propofol mixture sedation; Procedure: Propofol Sedation
Sponsors: University of Utah; University of Utah
Recruiting - verified August 2011 - Condition: Multiple Sclerosis
Intervention: Drug: Lithium Carbonate
Sponsors: Department of Veterans Affairs; Department of Veterans Affairs
Recruiting - verified May 2012 - Condition: Sleep Disorders
Interventions: Other: Normal saline infusion; Drug: Dexmedetomidine; Drug: Propofol
Sponsors: University of California, San Francisco; University of California, San Francisco; Masimo Labs
Recruiting - verified May 2012 - Condition: Major Depressive Disorder
Intervention: Drug: ketamine
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified April 2012 - Condition: Sickle Cell Disease
Intervention: Procedure: Femoral Nerve Block
Sponsors: Mount Sinai School of Medicine; Mount Sinai School of Medicine
Recruiting - verified January 2012 - Conditions: Alcohol Abuse; Alcohol Dependence
Interventions: Drug: ondansetron; Drug: placebo ondansetron; Drug: Ondansetron
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified February 2012 - Condition: Type 1 Diabetes
Interventions: Drug: Pramlintide; Drug: Exenatide; Drug: Insulin
Sponsors: Albert Einstein College of Medicine of Yeshiva University; Albert Einstein College of Medicine of Yeshiva University; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified May 2012 - Condition: Major Depressive Disorder (MDD)
Interventions: Drug: Amisulpride; Drug: Placebo
Sponsors: Mclean Hospital; Mclean Hospital; National Institute of Mental Health (NIMH)
Recruiting - verified March 2012 - Condition: Pain
Interventions: Drug: Placebo; Drug: Group A (study group) Lidocaine
Sponsors: Northwestern University; Northwestern University
Recruiting - verified October 2011 - Conditions: HIV; AIDS; Opioid Dependence; Drug Dependence
Intervention: Drug: Depot Naltrexone
Sponsors: Yale University; Yale University; Baystate Medical Center
Recruiting - verified August 2011 - Conditions: Cocaine Abuse; Cocaine Dependence; Postpartum Period
Interventions: Drug: Progesterone; Other: Placebo
Sponsors: Yale University; Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Condition: Use of Atypical Antipsychotics During Pregnancy
Intervention:
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; AstraZeneca; Bristol-Myers Squibb; Ortho-McNeil Janssen Scientific Affairs, LLC; Pfizer
Recruiting - verified July 2011 - Condition: Bipolar Disorder, Pediatric
Interventions: Drug: asenapine; Drug: Placebo to match asenapine
Sponsors: Schering-Plough; Schering-Plough
Recruiting - verified May 2012 - Condition: Cocaine Abuse
Intervention: Drug: L-dopa / carbidopa / entacapone (LCE)
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute on Drug Abuse (NIDA); Columbia University
Recruiting - verified December 2011 - Condition: Tourette's Syndrome
Intervention: Drug: Ecopipam
Sponsors: Psyadon Pharma; Psyadon Pharma
Recruiting - verified May 2012 - Condition: Healthy Volunteers
Interventions: Drug: Almorexant; Drug: Almorexant; Drug: Zolpidem 10mg; Drug: Placebo
Sponsors: Northern California Institute of Research and Education; Northern California Institute of Research and Education; U.S. Army Medical Research and Materiel Command
Recruiting - verified August 2010 - Conditions: Spinal Stenosis; Low Back Pain
Interventions: Procedure: Epidural steroid with local anesthetic injection; Procedure: Epidural local anesthetic injection
Sponsors: University of Washington; University of Washington; Kaiser Permanente; University of California, San Francisco; Henry Ford Hospital; Harvard Pilgrim Health Care; Harvard Vanguard Medical Associates; University of Colorado, Denver; Mayo Clinic
Recruiting - verified October 2011 - Conditions: Low Back Pain; Pain
Interventions: Drug: Analgesic and co-analgesic therapy; Behavioral: Pain self-management/coping skills treatment
Sponsors: Department of Veterans Affairs; Department of Veterans Affairs
Recruiting - verified February 2012 - Condition: Healthy
Interventions: Other: Saline; Drug: PF-02545920; Other: Ketamine; Drug: PF-02545920; Other: Saline; Other: Placebo; Other: Ketamine; Other: Placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified April 2012 - Condition: Schizophrenia
Interventions: Drug: RO4917838; Drug: RO4917838; Drug: olanzapine; Drug: placebo
Sponsors: Hoffmann-La Roche; Hoffmann-La Roche
Recruiting - verified May 2012 - Condition: Female Patients With High Tone Pelvic Floor Dysfunction
Interventions: Drug: Vaginal Diazepam Suppository; Drug: Placebo Suppository
Sponsors: TriHealth Inc.; TriHealth Inc.
Recruiting - verified September 2011 - Condition: Retinitis Pigmentosa
Interventions: Drug: Valproic Acid; Drug: Placebo
Sponsors: National Neurovision Research Institute; National Neurovision Research Institute; Department of Defense
Recruiting - verified April 2012 - Condition: Autistic Disorder
Interventions: Drug: Aripiprazole; Drug: Placebo
Sponsors: Bristol-Myers Squibb; Bristol-Myers Squibb
Recruiting - verified February 2012 - Condition: Cocaine Use
Intervention: Device: Repetitive Transcranial Magnetic Stimulation
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA); University of Maryland
Not yet recruiting - verified August 2011 - Condition: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: dextromethorphan hydrobromide; Drug: gamma-secretase/Notch signalling pathway inhibitor RO4929097; Drug: ketoconazole; Drug: midazolam hydrochloride; Drug: omeprazole; Drug: rifampin; Drug: tolbutamide
Sponsors: National Cancer Institute (NCI); University of Wisconsin, Madison; National Cancer Institute (NCI)
Recruiting - verified July 2011 - Condition: Pathological Gambling
Intervention: Drug: Ecopipam
Sponsors: Psyadon Pharma; Psyadon Pharma
Recruiting - verified May 2012 - Conditions: Delirium; Impaired Cognition; Long Term Psychologic Disorders
Interventions: Drug: Haloperidol; Drug: Ziprasidone; Drug: Placebo
Sponsors: Vanderbilt University; Vanderbilt University
Recruiting - verified December 2011 - Conditions: Pro-inflammatory Activity; Immunologic Activity Alteration [PE]
Interventions: Drug: Fentanyl; Other: Cold pressor test; Other: Fentanyl plus cold pressor test
Sponsors: University of California, Los Angeles; University of California, Los Angeles
Recruiting - verified February 2012 - Conditions: Cystoscopes; Baxter Anaesthesia Brand of Desflurane; Sevoflurane
Interventions: Drug: Desflurane; Drug: Sevoflurane
Sponsors: Ohio State University; Ohio State University; Baxter Healthcare Corporation
Recruiting - verified July 2011 - Condition: Primary Headaches (Includes Migraines, Tension, Cluster Headaches)
Interventions: Drug: Droperidol; Drug: Metoclopramide; Drug: Diphenhydramine
Sponsors: University of Iowa; University of Iowa
Recruiting - verified July 2011 - Condition: Chronic Oral Food Refusal
Interventions: Drug: Amitriptyline 1 mg/kg; Drug: Placebo
Sponsors: University of Kansas; Ann Davis, PhD, MPH, ABPP
Recruiting - verified March 2012 - Condition: Autistic Disorder
Interventions: Drug: Aripiprazole; Drug: Risperidone
Sponsors: Medical University of South Carolina; Medical University of South Carolina
Recruiting - verified May 2012 - Condition: Post Operative Pain
Intervention: Drug: oxymorphone HCl
Sponsors: Endo Pharmaceuticals; Endo Pharmaceuticals
Recruiting - verified November 2011 - Condition: Essential Tremor
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified June 2011 - Conditions: Deep Brain Stimulation (DBS); Blood Flow; Brain Oxygenation
Interventions: Drug: dexmedetomidine; Drug: propofol
Sponsors: Outcomes Research Consortium; Outcomes Research Consortium
Recruiting - verified June 2011 - Condition: Post Operative Pain
Interventions: Drug: Dilaudid PCA; Drug: Dilaudid IV Scheduled
Sponsors: TriHealth Inc.; TriHealth Inc.
Recruiting - verified September 2011 - Condition: Pain
Intervention: Drug: Oxycodone HCl controlled-release tablets
Sponsors: Purdue Pharma LP; Purdue Pharma LP
Recruiting - verified May 2012 - Condition: Contraception
Interventions: Drug: Lidocaine; Drug: Lubricant
Sponsors: University of Tennessee; University of Tennessee
Recruiting - verified June 2011 - Conditions: Schizophrenia, Paranoid; Schizophrenia, Disorganized; Schizophrenia, Undifferentiated
Intervention: Drug: asenapine
Sponsors: Schering-Plough; Schering-Plough
Recruiting - verified May 2012 - Conditions: Schizophrenia, Paranoid; Schizophrenia, Disorganized; Schizophrenia, Undifferentiated
Interventions: Drug: asenapine; Drug: asenapine; Drug: placebo BID
Sponsors: Schering-Plough; Schering-Plough
Recruiting - verified May 2012 - Condition: Cocaine Related Disorders
Intervention:
Sponsors: Medical University of South Carolina; Medical University of South Carolina; National Institute on Drug Abuse (NIDA)
Recruiting - verified July 2011 - Conditions: Airway Reflexes, Protective; Recovery After Neuromuscular Block; Anesthetic Recovery
Interventions: Drug: Sevoflurane; Drug: Desflurane
Sponsors: University of California, San Francisco; University of California, San Francisco; Baxter Healthcare Corporation
Recruiting - verified March 2012 - Conditions: Cancers; Chronic Pain
Intervention: Device: Implantation of Morphine Sulfate delivring programmable pump
Sponsors: The Alfred E. Mann Foundation for Scientific Research; The Alfred E. Mann Foundation for Scientific Research
Recruiting - verified March 2012 - Condition: Interstitial Cystitis
Interventions: Drug: Dexmedetomidine; Drug: Normal Saline
Sponsors: University of Rochester; University of Rochester
Recruiting - verified August 2011 - Condition: Thyroid Neoplasm
Intervention: Drug: Valproic Acid
Sponsors: National Institutes of Health Clinical Center (CC); National Cancer Institute (NCI)
Recruiting - verified September 2011 - Conditions: Schizophrenia; Bipolar Disorder
Interventions: Drug: Risperidone long acting injectable - New Starts; Drug: Risperidone long acting injectable - Continuous Users; Drug: Paliperidone Palmitate -New and Continuous Users; Drug: Other Antipsychotics - New Starts
Sponsors: Janssen Scientific Affairs, LLC; Janssen Scientific Affairs, LLC
Recruiting - verified May 2012 - Conditions: Opioid Related Disorders; Opioid Dependence; Opioid Addiction
Interventions: Drug: Buprenorphine/naloxone; Drug: Clonidine; Drug: Tramadol ER
Sponsors: National Institute on Drug Abuse (NIDA); National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2012 - Condition: Lung Cancer
Interventions: Other: General-epidural anesthesia and analgesia; Other: Balanced general anesthesia and postoperative opioids
Sponsors: Outcomes Research Consortium; Outcomes Research Consortium
Recruiting - verified August 2011 - Condition: Chronic Rhinosinusitis.
Interventions: Drug: Propofol and Remifentanyl; Drug: Sevoflurane and Remifentanyl
Sponsors: The University of Texas Health Science Center, Houston; The University of Texas Health Science Center, Houston
Recruiting - verified February 2012 - Conditions: Cocaine; Alcohol Dependence
Interventions: Drug: Aprepitant; Drug: Placebo
Sponsors: University of Pennsylvania; University of Pennsylvania; National Institute on Drug Abuse (NIDA)
Recruiting - verified August 2011 - Condition: Pain
Intervention: Drug: Ketamine group
Sponsors: Northwestern University; Northwestern University
Recruiting - verified February 2012 - Condition: Treatment Refractory Depression
Interventions: Drug: Ketamine; Drug: Clonidine; Drug: placebo
Sponsors: Washington University School of Medicine; Washington University School of Medicine; University of Miami
Not yet recruiting - verified March 2012 - Condition: Arrhythmia
Intervention:
Sponsors: University of California, San Francisco; University of California, San Francisco
Recruiting - verified January 2012 - Condition: Subsyndromal Delirium
Interventions: Drug: Haloperidol decanoate; Drug: Placebo
Sponsors: Northeastern University; Northeastern University; National Institute on Aging (NIA)
Recruiting - verified April 2012 - Conditions: Low Back Pain; Radiating Pain
Interventions: Other: Entonox; Other: Oxygen
Sponsors: Outcomes Research Consortium; Outcomes Research Consortium
Recruiting - verified August 2011 - Condition: Anorexia Nervosa
Interventions: Drug: Olanzapine; Drug: Placebo
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute of Mental Health (NIMH); Weill Medical College of Cornell University; University of Pittsburgh; Johns Hopkins University; University of Toronto
Recruiting - verified April 2012 - Conditions: Cesarean Delivery; Pain Relief; TAP Block
Interventions: Drug: Placebo; Drug: Group 2 - 15mL 0.25% ropivacaine per side; Drug: . Group 3; Drug: 15mL 0.75% ropivacaine per side
Sponsors: Northwestern University; Northwestern University
Recruiting - verified August 2011 - Conditions: Risk Reduction Behavior; Health Behavior; Sexual Behavior; Adolescent Behavior; Cannabis
Interventions: Behavioral: INFORMATION-ONLY SEXUAL RISK REDUCTION (INFO-ONLY); Behavioral: SEXUAL PLUS ALCOHOL RISK REDUCTION (SRRI+ETOH); Behavioral: SEXUAL + ALCOHOL + MARIJUANA RISK REDUCTION
Sponsors: University of New Mexico; University of New Mexico; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified August 2011 - Conditions: Depression; Bipolar
Interventions: Drug: ziprasidone; Drug: Sugar pill
Sponsors: Tufts Medical Center; Tufts Medical Center; Duke University; University of South Carolina
Recruiting - verified July 2011 - Condition: Orthopedic Surgery of Lower Extremity
Interventions: Drug: 0.2% ropivacaine; Drug: saline
Sponsors: Wake Forest University; Wake Forest University; I-Flow
Recruiting - verified February 2012 - Condition: Bipolar Disorder
Interventions: Drug: Lithium Carbonate; Drug: Placebo
Sponsors: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - verified February 2012 - Conditions: Pain; Obesity
Interventions: Drug: Lidocaine Infusion; Drug: Normal Saline
Sponsors: Northwestern University; Northwestern University
Recruiting - verified May 2012 - Condition: Alcohol Dependence
Interventions: Drug: Quetiapine XR plus mirtazapine; Drug: Quetiapine fumarate extended release (Quetiapine XR)
Sponsors: Dartmouth-Hitchcock Medical Center; Dartmouth-Hitchcock Medical Center
Recruiting - verified February 2012 - Condition: Neonatal Abstinence Syndrome
Interventions: Drug: Clonidine; Drug: Phenobarbital
Sponsors: Baystate Medical Center; Baystate Medical Center
Recruiting - verified April 2012 - Conditions: Postoperative Pain; Total Knee Replacement
Interventions: Drug: Nerve Block; Drug: Periarticular Injection
Sponsors: Mayo Clinic; Mayo Clinic
Recruiting - verified August 2011 - Condition: Acute Traumatic Pain in Aeromedical Patients
Interventions: Drug: Ketamine; Drug: Fentanyl
Sponsors: University of Utah; University of Utah
Not yet recruiting - verified July 2011 - Condition: Vaginal Surgery
Interventions: Drug: Belladonna and Opium Suppositories; Drug: Placebo Suppositories
Sponsors: Mayo Clinic; Mayo Clinic
Recruiting - verified August 2011 - Condition: Schizophrenia
Interventions: Drug: Aripiprazole; Drug: Aripiprazole
Sponsors: Otsuka Pharmaceutical Development & Commercialization, Inc.; Otsuka Pharmaceutical Development & Commercialization, Inc.
Recruiting - verified May 2012 - Condition: Cervical Radiculopathy
Interventions: Other: Gabapentin and/or Nortriptyline, Physical therapy; Procedure: Epidural Steroid Injections (ESI); Other: Combination treatment
Sponsors: Johns Hopkins University; Johns Hopkins University; Walter Reed Army Medical Center
Recruiting - verified September 2010 - Conditions: Pain Perception; Phlebotomy
Interventions: Drug: 4% lidocaine gel application with sham microneedle device; Drug: Microneedle-facilitated lidocaine application
Sponsors: University of Oklahoma; University of Oklahoma
Not yet recruiting - verified March 2012 - Condition: Labor Pain
Interventions: Drug: Morphine; Drug: Saline
Sponsors: Beth Israel Deaconess Medical Center; Beth Israel Deaconess Medical Center
Recruiting - verified June 2011 - Condition: Substance Abuse Disorder
Interventions: Behavioral: Low intensity care; Behavioral: Voucher reinforcement
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute on Drug Abuse (NIDA)
Recruiting - verified August 2011 - Condition: Cocaine Dependence
Interventions: Drug: Zonisamide; Drug: Placebo; Drug: Cocaine Hydrochloride; Behavioral: Neurocognitive and Performance Battery; Behavioral: Smoking Assessments
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute on Drug Abuse (NIDA)
Recruiting - verified June 2011 - Conditions: Bipolar Disorder; Depression
Interventions: Drug: IPSRT plus placebo (IPSRT-PLA); Drug: IPSRT plus quetiapine
Sponsors: University of Pittsburgh; University of Pittsburgh; National Institute of Mental Health (NIMH)
Recruiting - verified January 2012 - Condition: Cocaine Dependence
Interventions: Drug: Mifepristone; Drug: placebo
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute
Recruiting - verified December 2011 - Conditions: Alcohol Withdrawal Delirium; Alcohol Withdrawal Associated Autonomic Hyperactivity; Alcohol Withdrawal Hallucinosis; Alcohol Withdrawal-Induced Delirium Tremens
Interventions: Drug: Dexmedetomidine; Drug: Placebo
Sponsors: Denver Health and Hospital Authority; Denver Health and Hospital Authority
Recruiting - verified April 2012 - Condition: Epilepsy
Intervention: Drug: Intravenous Carbamazepine (IV CBZ)
Sponsors: Lundbeck LLC; Lundbeck LLC; CyDex Pharmaceuticals, Inc.; ICON Clinical Research; Quintiles
Recruiting - verified April 2012 - Condition: Schizophrenia
Interventions: Drug: LY2140023; Drug: Olanzapine; Drug: Aripiprazole; Drug: Risperidone; Drug: Quetiapine
Sponsors: Eli Lilly and Company; Eli Lilly and Company
Recruiting - verified May 2012 - Conditions: Major Depressive Disorder; Suicidality
Interventions: Drug: paliperidone; Drug: placebo; Drug: lithium
Sponsors: University of Alabama at Birmingham; University of Alabama at Birmingham; American Foundation for Suicide Prevention; Ortho-McNeil Janssen Scientific Affairs, LLC
Recruiting - verified March 2012 - Conditions: Hazardous Alcohol Use; Binge Drinking; High Risk Sexual Behaviors; HIV Risk Reduction; HIV Infection
Interventions: Behavioral: Computerized brief alcohol intervention with IVR booster calls; Behavioral: Computer delivered brief alcohol intervention; Behavioral: Attention Control
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Not yet recruiting - verified June 2011 - Conditions: Schizophrenia; Schizoaffective Disorder
Interventions: Drug: haloperidol decanoate; Drug: paliperidone palmitate
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute of Mental Health (NIMH); Duke University; University of North Carolina, Chapel Hill
Recruiting - verified January 2012 - Condition: Vulvodynia
Intervention: Drug: Gabapentin
Sponsors: University of Tennessee; University of Tennessee; University of Tennessee Health Science Center
Not yet recruiting - verified November 2011 - Conditions: Pain; Ventilatory Depression
Intervention: Drug: hydromorphone
Sponsors: Northwestern University; Northwestern University
Recruiting - verified February 2012 - Conditions: Adolescent Schizophrenia; Child or Adolescent Bipolar I Disorder, Manic or Mixed Episode With or Without Psychotic Features
Intervention: Drug: Aripiprazole
Sponsors: Otsuka Pharmaceutical Development & Commercialization, Inc.; Otsuka Pharmaceutical Development & Commercialization, Inc.
Recruiting - verified May 2012 - Condition: Schizophrenia
Interventions: Drug: RO4917838; Drug: placebo; Drug: standard antipsychotic therapy
Sponsors: Hoffmann-La Roche; Hoffmann-La Roche
Recruiting - verified May 2012 - Condition: Schizophrenia
Interventions: Drug: paliperidone; Drug: risperidone; Drug: haloperidole; Drug: perphenazine; Drug: aripiprazole; Drug: quetiapine; Drug: paliperidone palmitate; Drug: olanzapine
Sponsors: Janssen Scientific Affairs, LLC; Janssen Scientific Affairs, LLC
Recruiting - verified May 2012 - Condition: Seizure Disorders
Intervention: Drug: Dexmedetomidine
Sponsors: University of California, San Francisco; University of California, San Francisco
Recruiting - verified June 2011 - Condition: Chronic Pain
Interventions: Drug: Extended Release Oxycodone - Crossover Period I; Drug: Immediate release oxycodone - Crossover period 2; Device: Actigraphy analysis; Device: Portable polysomnography
Sponsors: University of Rochester; University of Rochester
Recruiting - verified August 2011 - Condition: Pain
Interventions: Drug: Placebo administration; Drug: Dexmedetomidine administration
Sponsors: Northwestern University; Northwestern University
Recruiting - verified February 2012 - Condition: Pain
Interventions: Drug: Saline; Drug: Ketamine continuous infusion
Sponsors: Northwestern University; Northwestern University
Recruiting - verified February 2012 - Condition: Brain Cancer
Intervention: Drug: Temozolomide, bevacizumab, lithium, radiation
Sponsors: New York University School of Medicine; New York University School of Medicine; Genentech; Ohio State University; Atlantic Health System
Recruiting - verified February 2012 - Conditions: Chemotherapeutic Agent Toxicity; Colorectal Cancer; Neuropathy; Neurotoxicity
Interventions: Drug: calcium gluconate; Drug: magnesium sulfate; Other: placebo
Sponsors: National Cancer Institute (NCI); North Central Cancer Treatment Group; National Cancer Institute (NCI)
Recruiting - verified May 2012 - Condition: Obsessive-Compulsive Disorder
Interventions: Drug: Ketamine infusion; Other: Saline
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute
Recruiting - verified December 2011 - Conditions: Sarcoma; Soft Tissue Sarcoma; Locally Advanced Sarcoma; Unresectable Sarcoma; Metastatic Sarcoma
Intervention: Drug: Bevacizumab, Gemcitabine, docetaxel and valproic acid
Sponsors: University of Iowa; University of Iowa; Genentech
Recruiting - verified June 2011 - Condition: Diabetic Peripheral Neuropathy
Interventions: Other: Skin biopsy; Other: Skin biopsy
Sponsors: Albany Medical College; Albany Medical College; Endo Pharmaceuticals
Recruiting - verified December 2010 - Condition: Postoperative Pain
Intervention: Drug: cyclobenzaprine
Sponsors: NorthShore University HealthSystem Research Institute; NorthShore University HealthSystem Research Institute
Recruiting - verified March 2012 - Conditions: Pain; Obesity; Surgery
Interventions: Drug: Placebo; Drug: (study group) will receive a bilateral TAP block using 30 cc of 0.5% ropivacaine on each side.
Sponsors: Northwestern University; Northwestern University
Recruiting - verified May 2012 - Condition: Pulmonary Hypertension
Intervention: Drug: Dexmedetomidine
Sponsors: Children's Hospital of Philadelphia; Aruna Nathan; Children's Hospital of Philadelphia
Recruiting - verified May 2012 - Condition: Drug Dependence
Intervention: Drug: 2-4 of the drugs listed below
Sponsors: University of Arkansas; University of Arkansas; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Conditions: Post Operative Nausea and Vomiting; Rescue Emetic Therapy
Interventions: Drug: Metaclopramide; Drug: Ondansetron; Drug: diphenhydramine; Drug: Saline
Sponsors: Children's Hospital of Pittsburgh; Children's Hospital of Pittsburgh
Recruiting - verified September 2009 - Conditions: Pain; Breast Cancer; Lung Cancer
Interventions: Drug: Gabapentin; Drug: Placebo
Sponsors: Stanford University; Stanford University
Recruiting - verified September 2011 - Conditions: Neoplasms, Cystic, Mucinous, and Serous; Pancreatic Neoplasms; Ultrasonography, Interventional
Intervention: Procedure: EUS and/or ERCP with ethanol injections of pancreatic cyst
Sponsors: Mayo Clinic; Mayo Clinic
Recruiting - verified July 2011 - Condition: Nephrectomy
Interventions: Procedure: TAP block placement with placebo; Procedure: Placement of block with ropivacaine
Sponsors: Mayo Clinic; Mayo Clinic
Recruiting - verified January 2012 - Condition: Opioid Dependence
Interventions: Drug: Memantine; Drug: Memantine; Drug: Placebo
Sponsors: University of Massachusetts, Worcester; University of Massachusetts, Worcester; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Conditions: Diabetes; Obesity; Weight Gain
Intervention: Behavioral: Behavioral Weight Loss Program
Sponsors: Department of Veterans Affairs; Department of Veterans Affairs
Recruiting - verified December 2011 - Condition: Alcohol Misuse
Interventions: Behavioral: Computer-delivered Brief Intervention (CBI); Behavioral: Intervener-delivered Brief Intervention (IBI); Behavioral: Adapted Motivational Enhancement Therapy (AMET)
Sponsors: University of Michigan; University of Michigan; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified December 2010 - Conditions: Drug Abuse; Cocaine Dependence
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA); National Institute of Mental Health (NIMH)
Recruiting - verified July 2011 - Condition: Major Depressive Disorder
Intervention: Drug: tranylcypromine
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute of Mental Health (NIMH)
Recruiting - verified December 2011 - Conditions: Cocaine Dependence; Cocaine Addiction; Cocaine Abuse; Substance Abuse
Interventions: Drug: Placebo; Drug: Rivastigmine; Drug: Huperzine A; Drug: Rivastigmine; Drug: Huperzine A
Sponsors: Baylor College of Medicine; Baylor College of Medicine; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Condition: Depression
Interventions: Drug: lithium and Venlafaxine; Procedure: ECT
Sponsors: Mount Sinai School of Medicine; Mount Sinai School of Medicine; National Institute of Mental Health (NIMH)
Recruiting - verified March 2012 - Condition: Opioid Dependence
Interventions: Drug: injectable naltrexone plus dronabinol; Drug: Naltrexone plus placebo
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute on Drug Abuse (NIDA)
Recruiting - verified May 2012 - Condition: Blood Loss
Interventions: Drug: propofol; Drug: sevoflurane
Sponsors: University of Chicago; University of Chicago
Recruiting - verified September 2011 - Condition: Headache
Interventions: Drug: Metoclopramide; Drug: Ketorolac
Sponsors: Montefiore Medical Center; Montefiore Medical Center
Recruiting - verified April 2012 - Condition: High Grade Sarcoma
Intervention: Drug: Valproic Acid
Sponsors: Columbia University; Columbia University
Recruiting - verified October 2011 - Condition: Breast Cancer
Intervention: Drug: VPA FEC100
Sponsors: University of California, San Francisco; University of California, San Francisco; H. Lee Moffitt Cancer Center and Research Institute
Recruiting - verified March 2012 - Condition: To Evaluate Two Paradigms for Simultaneous Assessment of Hepatic and Intestinal CYP3A Activity
Intervention: Drug: of d0- and d3-alfentanil
Sponsors: Washington University School of Medicine; Washington University School of Medicine
Recruiting - verified February 2012 - Condition: Cancer
Intervention: Drug: Valproic Acid
Sponsors: University of Utah; University of Utah
Recruiting - verified January 2012 - Condition: Hot Flashes
Intervention: Drug: Gabapentin
Sponsors: Abramson Cancer Center of the University of Pennsylvania; Abramson Cancer Center of the University of Pennsylvania
Recruiting - verified May 2012 - Conditions: Neoplasms; Constipation; Opioid-Related Disorders
Intervention: Drug: Methylnaltrexone bromide
Sponsors: University of Vermont; University of Vermont
Recruiting - verified March 2012 - Condition: Ambulatory Surgery
Interventions: Drug: Dexmedetomidine infusion; Drug: propofol
Sponsors: University of Medicine and Dentistry New Jersey; University of Medicine and Dentistry New Jersey
Recruiting - verified August 2011 - Condition: Alcohol Reactivity
Interventions: Drug: varenicline; Drug: placebo
Sponsors: Yale University; Yale University
Recruiting - verified January 2012 - Conditions: Low Bispectral Index; Low Mean Arterial Blood Pressure; Low End-tidal Anesthetic Concentration
Intervention:
Sponsors: Outcomes Research Consortium; Outcomes Research Consortium
Recruiting - verified August 2011 - Condition: Opiate Addiction
Interventions: Drug: Buprenorphine/naloxone; Drug: Naltrexone
Sponsors: State University of New York at Buffalo; State University of New York at Buffalo
Recruiting - verified February 2011 - Condition: Hepatitis C
Interventions: Drug: Midazolam; Drug: BMS-791325
Sponsors: Bristol-Myers Squibb; Bristol-Myers Squibb
Not yet recruiting - verified February 2012 - Condition: Sedation
Interventions: Drug: propofol; Drug: alfentanil
Sponsors: Minneapolis Medical Research Foundation; Minneapolis Medical Research Foundation
Recruiting - verified February 2012 - Condition: Sedation
Interventions: Drug: Propofol; Drug: Alfentanil; Drug: Nitrous Oxide
Sponsors: Minneapolis Medical Research Foundation; Minneapolis Medical Research Foundation
Recruiting - verified February 2012 - Condition: Opiate Dependence
Intervention: Behavioral: Linkage
Sponsors: Butler Hospital; Butler Hospital; Boston Medical Center
Recruiting - verified March 2012 - Conditions: Bipolar I Disorder; Schizophrenia
Interventions: Drug: Olanzapine; Behavioral: Standard behavioral weight intervention; Behavioral: Intense behavioral weight intervention
Sponsors: Eli Lilly and Company; Eli Lilly and Company
Recruiting - verified May 2012 - Condition: Drug Dependence
Intervention: Drug: Oxytocin Nasal Spray
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified July 2011 - Conditions: Cannabis Dependence; Cannabis Withdrawal; Cognitive Deficits
Interventions: Drug: gabapentin 1200mg/day; Drug: Placebo
Sponsors: The Scripps Research Institute; The Scripps Research Institute
Recruiting - verified March 2012 - Condition: Cocaine Dependence
Interventions: Drug: TA-CD Vaccination; Other: Placebo Injection
Sponsors: Baylor College of Medicine; Baylor College of Medicine; National Institute on Drug Abuse (NIDA); US Department of Veterans Affairs Cooperative Studies Program; VA Maryland Health Care System; Columbia University; VA New York Harbor Healthcare System; University of Pennsylvania; Johns Hopkins University; University of Cincinnati; Celtic Pharma Development Services
Recruiting - verified September 2011 - Conditions: Nausea; Vomiting
Interventions: Drug: aprepitant; Drug: Ondansetron
Sponsors: University of Vermont; University of Vermont; Mayo Clinic; Comprehensive Cancer Center of Wake Forest University
Recruiting - verified March 2012 - Condition: Epilepsy
Intervention: Drug: Melatonin
Sponsors: Children's Hospital Medical Center, Cincinnati; Children's Hospital Medical Center, Cincinnati
Recruiting - verified January 2012 - Conditions: Hematologic Diseases; Acute Myelogenous Leukemia; Myelodysplastic Syndrome; Chronic Myelogenous Leukemia
Interventions: Drug: Ondansetron; Drug: Aprepitant
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center
Recruiting - verified January 2012 - Condition: Major Depressive Disorder With Psychotic Features
Interventions: Drug: Quetiapine monotherapy; Drug: Quetiapine with SSRI
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified February 2012 - Condition: Postoperative Pain
Interventions: Drug: Gabapentin; Drug: pregabalin
Sponsors: Loma Linda University; Loma Linda University
Recruiting - verified March 2012 - Condition: Major Depressive Disorder
Intervention: Drug: escitalopram and adjunctive aripiprazole and placebo
Sponsors: Washington University School of Medicine; Washington University School of Medicine
Recruiting - verified August 2011 - Condition: Spastic Cerebral Palsy
Interventions: Drug: Extended-release Epidural morphine (EREM) 80; Drug: Extended-release Epidural Morphine (EREM) 120; Drug: Control: Saline
Sponsors: Washington University School of Medicine; Washington University School of Medicine
Recruiting - verified August 2011 - Conditions: Drug Abuse; Cocaine Dependence
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified March 2012 - Conditions: Depression; Anxiety
Intervention: Drug: Quetiapine-XR
Sponsors: Loyola University; Loyola University
Recruiting - verified September 2011 - Conditions: At-risk Drinking; Type 2 Diabetes
Interventions: Behavioral: Brief alcohol intervention; Behavioral: General health education
Sponsors: Rhode Island Hospital; Rhode Island Hospital
Recruiting - verified July 2009 - Conditions: Anesthesia; Forefoot Surgery
Intervention: Procedure: elective forefoot surgery
Sponsors: OrthoCarolina Research Institute, Inc.; OrthoCarolina Research Institute, Inc.
Recruiting - verified January 2012 - Conditions: Obesity; Elective Surgery
Intervention:
Sponsors: Children's Hospital Medical Center, Cincinnati; Children's Hospital Medical Center, Cincinnati
Recruiting - verified January 2012 - Conditions: Alcohol-related Disorders; Post-traumatic Stress Disorder
Interventions: Behavioral: Seeking Safety; Behavioral: Couple-Based Treatment for Alcohol Use Disorders and PTSD
Sponsors: Department of Veterans Affairs; Department of Veterans Affairs
Recruiting - verified March 2012 - Conditions: Delayed Sleep Phase Disorder; Jet-lag; Shift-work Disorder
Interventions: Dietary Supplement: Melatonin; Dietary Supplement: Placebo
Sponsors: Brigham and Women's Hospital; Brigham and Women's Hospital
Recruiting - verified June 2011 - Condition: Cognitive Decline
Interventions: Drug: Lidocaine; Drug: Placebo
Sponsors: Duke University; Duke University; National Institutes of Health (NIH); CAS Medical Systems, Inc.
Recruiting - verified May 2012 - Conditions: Pain Control; UPJ Correction
Interventions: Device: Wound catheter; Device: wound catheter
Sponsors: Children's Hospital Boston; Children's Hospital Boston
Recruiting - verified July 2011 - Conditions: Analgesia; Pain
Interventions: Drug: 20 ml of ropivacaine 0.5%; Drug: 30 ml of ropivacaine 0.5%; Drug: 40 ml of ropivacaine 0.5%
Sponsors: Baylor College of Medicine; Baylor College of Medicine
Recruiting - verified February 2012 - Condition: Migraine Headache
Interventions: Drug: bupivicaine/methylprednisolone (Active Injection); Drug: Placebo Injection
Sponsors: Mayo Clinic; Mayo Clinic
Recruiting - verified November 2011 - Condition: Opiate Addiction
Interventions: Other: Brief Intervention with Buprenorphine initiation; Behavioral: Brief Intervention
Sponsors: Yale University; Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified December 2011 - Conditions: Stroke; Cerebrovascular Accident
Interventions: Drug: lidocaine; Device: muscle stimulator
Sponsors: Department of Veterans Affairs; Department of Veterans Affairs
Recruiting - verified March 2012 - Condition: Lower Urinary Tract Symptoms
Interventions: Drug: dutasteride 0.5 mg, used with tolterodine ER 4mg or placebo; Drug: dutasteride
Sponsors: Siami, Paul F., M.D.; Siami, Paul F., M.D.; GlaxoSmithKline; Pfizer
Recruiting - verified July 2011 - Conditions: Alcoholism; Alcohol Dependence; Post-Tramatic Stress Disorder; fMRI
Intervention: Drug: Aprepitant
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified December 2011 - Condition: Arthroplasty, Replacement, Knee
Interventions: Drug: Depodur; Procedure: sciatic nerve block
Sponsors: University of Louisville; University of Louisville; EKR Therapeutics, Inc
Recruiting - verified August 2011 - Conditions: Insomnia; Blindness; Daytime Sleepiness
Interventions: Drug: Melatonin; Behavioral: Regular Sleep Schedule; Behavioral: Light
Sponsors: Oregon Health and Science University; Oregon Health and Science University
Recruiting - verified July 2011 - Condition: Marijuana Abuse
Intervention: Drug: bupropion, diazepam, dronabinol, ramelteon (Investigational Drug)
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute on Drug Abuse (NIDA)
Recruiting - verified May 2009 - Conditions: Fracture; Pain, Postoperative
Interventions: Drug: Methadone; Drug: Morphine
Sponsors: University of Louisville; University of Louisville
Recruiting - verified August 2011 - Conditions: Alcohol Abuse; Alcoholism
Interventions: Drug: Ondansetron + BASICS Plus; Drug: Placebo + BASICS Plus
Sponsors: University of Virginia; Bankole Johnson; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified February 2012 - Condition: Neurocognitive Function
Intervention:
Sponsors: Columbia University; Columbia University; Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); Office of Acquisitions and Grants Services (OAGS)
Recruiting - verified February 2012 - Condition: Borderline Personality Disorder
Interventions: Drug: quetiapine extended-release; Drug: Placebo
Sponsors: University of Minnesota - Clinical and Translational Science Institute; University of Minnesota - Clinical and Translational Science Institute; AstraZeneca; University of Iowa; Mclean Hospital
Recruiting - verified August 2011 - Condition: Ischemic Brain Injury
Interventions: Drug: xenon; Other: Hypothermia
Sponsors: Turku University Hospital; Turku University Hospital; Academy of Finland; Grant recipient Risto O Roine
Recruiting - verified June 2011 - Conditions: Glial Cell Tumors; Malignant Gliomas; Glioblastoma Multiforme; Anaplastic Astrocytoma; Gliomatosis Cerebri; Gliosarcoma; Brainstem Glioma
Interventions: Drug: Valproic acid; Drug: Bevacizumab; Radiation: Radiation therapy
Sponsors: Baylor College of Medicine; Baylor College of Medicine
Recruiting - verified February 2012 - Condition: Marijuana Dependence
Interventions: Drug: Buspirone; Drug: Placebo
Sponsors: Medical University of South Carolina; Medical University of South Carolina; National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2012 - Condition: Autistic Disorder
Interventions: Drug: Buspirone; Drug: Buspirone; Drug: Placebo
Sponsors: Chugani, Diane C.; Chugani, Diane C.
Recruiting - verified July 2011 - Condition: Lung Cancer
Intervention: Drug: Hydralazine and Valproic Acid
Sponsors: New Mexico Cancer Care Alliance; New Mexico Cancer Care Alliance
Recruiting - verified April 2012 - Conditions: HIV Infections; Hepatitis C
Interventions: Drug: Alcohol; Drug: Alcohol placebo
Sponsors: University of California, San Francisco; University of California, San Francisco
Recruiting - verified April 2012 - Conditions: Tobacco Use Cessation; Alcohol-related Disorders
Intervention: Behavioral: behavioral counseling plus contingency management
Sponsors: Yale University; Yale University; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified January 2012 - Conditions: Alcohol Dependence; Depression
Interventions: Behavioral: Interpersonal Psychotherapy for Co-occurring Alcohol Dependence and Major Depression (IPT-ADMD); Behavioral: Treatment as Usual
Sponsors: University of Rochester; University of Rochester; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified February 2012 - Conditions: HIV; Substance Abuse; HIV Infections
Interventions: Behavioral: Intensive Case Management; Drug: Buprenorphine; Behavioral: Money Management
Sponsors: Yale University; Yale University
Recruiting - verified June 2011 - Conditions: Blood Glucose; Lipids
Intervention:
Sponsors: Washington University School of Medicine; Washington University School of Medicine; Pfizer
Recruiting - verified March 2012 - Conditions: Tonsillectomy; Adenoidectomy; Pharmacokinetics
Intervention:
Sponsors: Children's Hospital of Philadelphia; Children's Hospital of Philadelphia; Children's Anesthesiology Associates, Ltd.
Not yet recruiting - verified February 2012 - Condition: Pervasive Developmental Disorder
Intervention: Drug: aripiprazole
Sponsors: Indiana University; Indiana University; National Institute of Mental Health (NIMH); Bristol-Myers Squibb
Recruiting - verified April 2012 - Conditions: Pain; Chronic Pain; Hyperalgesia
Intervention: Drug: Ketamine
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified March 2012 - Condition: High Triglycerides and Cholesterol
Intervention: Drug: Lovaza
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; GlaxoSmithKline
Recruiting - verified July 2011 - Condition: Postoperative Nausea and Vomiting
Interventions: Drug: aprepitant; Drug: Comparator: Ondansetron
Sponsors: Merck; Merck
Recruiting - verified May 2012 - Condition: Chemotherapy-Induced Nausea and Vomiting
Interventions: Drug: Experimental: aprepitant; Drug: Experimental: aprepitant; Drug: Experimental: aprepitant; Drug: Experimental: aprepitant; Drug: Experimental: aprepitant; Drug: Experimental: aprepitant; Drug: Experimental: fosaprepitant; Drug: Experimental: fosaprepitant; Drug: Experimental: fosaprepitant; Drug: Comparator: ondansetron
Sponsors: Merck; Merck
Recruiting - verified May 2012 - Condition: Nicotine Dependence
Intervention: Behavioral: Tobacco Research and Intervention Program
Sponsors: H. Lee Moffitt Cancer Center and Research Institute; H. Lee Moffitt Cancer Center and Research Institute; National Institutes of Health (NIH)
Recruiting - verified January 2012 - Conditions: Obesity; Binge Eating
Interventions: Behavioral: Behavioral Weight Loss; Behavioral: Behavioral Weight Loss + Guided self-help Cognitive-behavioral Therapy; Drug: Placebo; Drug: Sibutramine
Sponsors: Yale University; Yale University; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified March 2012 - Condition: Schizophrenia
Intervention: Drug: Folic Acid
Sponsors: University of Michigan; University of Michigan; National Institute of Mental Health (NIMH)
Recruiting - verified November 2011 - Conditions: Dementia; Alzheimer Disease; Dementia, Vascular; Sleep Disorders; Circadian Dysregulation
Interventions: Drug: Zolpidem CR; Drug: Zolpidem CR placebo
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified April 2012 - Condition: Cocaine Dependence
Interventions: Drug: Galantamine; Drug: placebo
Sponsors: Yale University; Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2012 - Condition: Psychotic Disorders
Interventions: Drug: Aripiprazole or Perphenazine; Drug: Metformin; Drug: Olanzapine, quetiapine, risperidone, ziprasidone, aripiprazole, asenapine, iloperidone, or lurasidone
Sponsors: National Institute of Mental Health (NIMH); National Institute of Mental Health (NIMH); Johns Hopkins University; University of Maryland; University of North Carolina, Chapel Hill; The Zucker Hillside Hospital
Recruiting - verified April 2012 - Condition: Risperidone-induced Hyperprolactinemia
Intervention: Dietary Supplement: Calcium and Vitamin D
Sponsors: University of Iowa; University of Iowa; National Institutes of Health (NIH); Children's Miracle Network
Recruiting - verified August 2011 - Conditions: Sleep Disorder; Blindness
Intervention: Drug: Melatonin
Sponsors: Oregon Health and Science University; Oregon Health and Science University
Recruiting - verified July 2011 - Conditions: Bladder Cancer; Cervical Cancer; Esophageal Cancer; Gastric Cancer; Head and Neck Cancer; Kidney Cancer; Leukemia; Liver Cancer; Lung Cancer; Pancreatic Cancer; Tobacco Use Disorder
Interventions: Drug: nicotine; Drug: varenicline; Other: placebo
Sponsors: Butler Hospital; Butler Hospital; National Cancer Institute (NCI)
Recruiting - verified March 2012 - Conditions: Cocaine Dependence; Cocaine-Related Disorders; Opioid-Related Disorders
Interventions: Drug: Airipiprazole; Drug: Placebo
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified July 2011 - Condition: Otitis Media
Interventions: Drug: dexmedetomidine; Drug: saline
Sponsors: Ochsner Health System; Ochsner Health System
Recruiting - verified October 2011 - Condition: Bipolar 1 Disorder
Interventions: Drug: Asenapine; Drug: Asenapine; Drug: Placebo
Sponsors: Schering-Plough; Schering-Plough
Recruiting - verified May 2012 - Condition: Sickle Cell Disease
Interventions: Drug: Morphine; Drug: Methadone; Drug: Methadone
Sponsors: Washington University School of Medicine; Washington University School of Medicine
Recruiting - verified February 2012 - Condition: Myocardial Ischemia
Interventions: Drug: Metoprolol; Drug: Esmolol; Drug: Placebo
Sponsors: University of Oklahoma; University of Oklahoma
Recruiting - verified August 2011 - Condition: Inguinal Hernia
Interventions: Drug: Regional Anesthesia; Drug: General Anesthesia
Sponsors: Children's Hospital Boston; Children's Hospital Boston; Royal Children's Hospital; Royal Hospital for Sick Children; Murdoch Childrens Research Institute; Food and Drug Administration (FDA)
Recruiting - verified August 2011 - Conditions: Stress Disorders, Post-Traumatic; PTSD; Depression; Anxiety Disorder
Interventions: Drug: Midazolam; Drug: Ketamine
Sponsors: Mount Sinai School of Medicine; Dennis Charney; Department of Defense
Recruiting - verified March 2012 - Conditions: Chronic Pain; Osteoarthritis
Intervention: Drug: MS Contin
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Nursing Research (NINR)
Recruiting - verified June 2011 - Conditions: Alcohol Dependence; Anxiety Disorder
Intervention: Drug: disulfiram plus lorazepam
Sponsors: University of New Mexico; University of New Mexico; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified January 2012 - Condition: Fibromyalgia
Interventions: Drug: quetiapine; Drug: Placebo
Sponsors: East Tennessee State University Research Foundation; East Tennessee State University Research Foundation
Recruiting - verified June 2011 - Conditions: Schizophrenia; Schizoaffective Disorder; Schizophreniform;; Bipolar I Disorder; Bipolar II; Bipolar NOS; Psychotic Disorder Not Otherwise Specified; Autism
Intervention: Drug: Betahistine
Sponsors: Nathan Kline Institute for Psychiatric Research; Nathan Kline Institute for Psychiatric Research; Stanley Medical Research Institute
Recruiting - verified June 2011 - Conditions: Heroin Dependence; Opioid-Related Disorders; Cocaine Abuse or Dependence
Intervention:
Sponsors: Wayne State University; Wayne State University; National Institute on Drug Abuse (NIDA)
Recruiting - verified October 2011 - Condition: Sleep Apnea, Obstructive
Intervention: Drug: Propofol sedation
Sponsors: University of California, San Francisco; University of California, San Francisco
Recruiting - verified May 2012 - Condition: Blindness
Interventions: Dietary Supplement: Melatonin; Dietary Supplement: Melatonin; Dietary Supplement: Melatonin
Sponsors: Oregon Health and Science University; Oregon Health and Science University; Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - verified June 2011 - Condition: Cocaine Dependence
Interventions: Drug: Ondansetron; Drug: Placebo
Sponsors: University of Virginia; University of Virginia; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Conditions: Heroin Dependence; Opioid-Related Disorders
Intervention:
Sponsors: Wayne State University; Wayne State University; National Institute on Drug Abuse (NIDA)
Recruiting - verified October 2011 - Condition: Colon Cancer
Interventions: Procedure: Regional anesthesia and analgesia; Drug: general anesthesia followed by opioid analgesia
Sponsors: Outcomes Research Consortium; Outcomes Research Consortium
Recruiting - verified May 2012 - Conditions: Headache; Migraine
Interventions: Drug: Ropivacaine; Drug: Normal saline
Sponsors: Children's Hospital of Pittsburgh; Children's Hospital of Pittsburgh
Recruiting - verified September 2010 - Condition: Alcoholism
Interventions: Drug: Seroquel; Drug: Placebo
Sponsors: University of Pennsylvania; University of Pennsylvania; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified April 2012 - Conditions: Surgery; Anesthesia; Children
Intervention:
Sponsors: The Society for Pediatric Anesthesia; The Society for Pediatric Anesthesia; Children's Hospital Medical Center, Cincinnati; Monroe Carell Jr Children's Hospital at Vanderbilt; Seattle Children's Hospital; Children's Hospital Boston; Emory-Children's Center; Texas Children's Hospital; Johns Hopkins University; Children's Hospital Los Angeles; Morgan Stanley Children's Hospital of New York; Children's Hospital of Philadelphia; Children's Hospital of Pittsburgh; Phoenix Children's Hospital; University of Michigan; Children's Research Institute
Recruiting - verified July 2011 - Condition: Opioid-Induced Constipation
Intervention: Drug: Methylnaltrexone bromide
Sponsors: Salix Pharmaceuticals; Salix Pharmaceuticals; Progenics Pharmaceuticals, Inc.
Recruiting - verified January 2012 - Condition: Opioid-Induced Constipation
Interventions: Drug: Methylnaltrexone bromide; Drug: Placebo
Sponsors: Salix Pharmaceuticals; Salix Pharmaceuticals; Progenics Pharmaceuticals, Inc.
Recruiting - verified January 2012 - Condition: Eating Disorders
Interventions: Radiation: Positron Emission Tomography (PET) using [11C]raclopride; Drug: Methylphenidate; Procedure: Magnetic Resonance Imaging (MRI) scan
Sponsors: National Institute of Mental Health (NIMH); National Institute of Mental Health (NIMH)
Recruiting - verified November 2011 - Conditions: Breast Cancer; Depression; Hot Flashes; Psychosocial Effects of Cancer and Its Treatment
Interventions: Drug: citalopram hydrobromide; Drug: escitalopram oxalate; Drug: gabapentin; Drug: sertraline hydrochloride; Drug: tamoxifen citrate; Drug: venlafaxine; Genetic: molecular genetic technique; Other: high performance liquid chromatography; Other: laboratory biomarker analysis; Other: pharmacological study; Procedure: adjuvant therapy
Sponsors: Mayo Clinic; Mayo Clinic; National Cancer Institute (NCI)
Recruiting - verified April 2012 - Condition: Constipation
Interventions: Drug: Lubiprostone; Drug: Senna
Sponsors: Rehabilitation Institute of Chicago; Rehabilitation Institute of Chicago; Takeda Pharmaceuticals North America, Inc.
Recruiting - verified September 2011 - Condition: Chronic Pain
Intervention:
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified January 2012 - Condition: Cocaine Dependence
Interventions: Drug: Oral micronized progesterone; Drug: Placebo
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute on Drug Abuse (NIDA)
Recruiting - verified May 2012 - Condition: Major Depressive Disorder
Interventions: Drug: Ziprasidone; Drug: Placebo
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; Vanderbilt University
Recruiting - verified April 2012 - Condition: Obsessive-Compulsive Disorder
Intervention: Drug: Paliperidone
Sponsors: University of South Florida; University of South Florida; Indiana University; Ortho-McNeil Janssen Scientific Affairs, LLC
Recruiting - verified March 2012 - Condition: Status Epilepticus
Intervention: Drug: lorazepam or diazepam
Sponsors: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - verified February 2012 - Condition: Substance-related Discorder
Interventions: Drug: Nicotine; Drug: Carfentanil
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA); Johns Hopkins University
Recruiting - verified June 2011 - Condition: Traumatic Brain Injury
Interventions: Drug: Carbamazepine; Drug: Placebo
Sponsors: Carolinas Healthcare System; Carolinas Healthcare System; U.S. Department of Education
Recruiting - verified February 2012 - Conditions: Diabetic Neuropathic Pain; Chronic Low Back Pain
Interventions: Drug: donepezil; Drug: duloxetine; Drug: donepezil 2.5 mg and duloxetine 30mg; Drug: placebo; Drug: gabapentin
Sponsors: Wake Forest University; Wake Forest University; National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified February 2012 - Condition: Chronic Pain
Intervention:
Sponsors: Rush University Medical Center; Asokumar Buvanendran
Recruiting - verified April 2012 - Condition: Shoulder Pain
Interventions: Drug: Lidocaine; Drug: Triamcinolone + Lidocaine; Drug: Triamcinolone + Lidocaine; Drug: Triamcinolone + Lidocaine
Sponsors: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - verified December 2011 - Conditions: Opiate Dependence; Chronic Pain
Interventions: Behavioral: CBT; Drug: Buprenorphine; Other: Educational Counseling; Other: Physician Management
Sponsors: Yale University; Yale University
Recruiting - verified May 2012 - Condition: Pediatric Bipolar Disorder
Intervention: Drug: paliperidone
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified July 2011 - Condition: Alcohol Drinking
Interventions: Drug: varenicline; Drug: bupropion; Drug: placebo
Sponsors: Yale University; Yale University
Recruiting - verified January 2012 - Condition: Cocaine Addiction
Interventions: Behavioral: I/GDC + VR/CER; Behavioral: I/GDC
Sponsors: Duke University; Duke University; National Institute on Drug Abuse (NIDA)
Recruiting - verified June 2011 - Condition: Medullary Thyroid Cancer
Intervention: Drug: Lithium carbonate
Sponsors: University of Wisconsin, Madison; University of Wisconsin, Madison
Recruiting - verified November 2011 - Conditions: Bipolar Disorder; Schizophrenia
Intervention:
Sponsors: University of Iowa; University of Iowa
Recruiting - verified January 2010 - Conditions: Minor Surgical Procedures With Monitored Anesthesia Care.; Driving Performance After Minor Ambulatory Surgery.
Interventions: Other: Control; Drug: Midazolam; Drug: Sufentanil; Drug: Propofol
Sponsors: Rush University Medical Center; Rush University Medical Center
Recruiting - verified April 2012 - Condition: Type 1 Diabetes
Interventions: Drug: Alprazolam; Drug: Placebo
Sponsors: University of Maryland; University of Maryland; National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified July 2011 - Condition: Cocaine Addictions
Interventions: Drug: sugar pill; Drug: carvedilol; Drug: Methadone
Sponsors: Yale University; Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified December 2011 - Conditions: Bipolar Disorder; Bipolar Depression
Interventions: Drug: citalopram + mood stabilizer; Procedure: FDG PET scans; Procedure: MRI structural scans; Procedure: Genotyping; Procedure: Blood Draw; Drug: placebo + mood stabilizer
Sponsors: Tufts Medical Center; Tufts Medical Center; National Institute of Mental Health (NIMH)
Recruiting - verified July 2011 - Conditions: Postoperative Delirium; PD; Postoperative Cognitive Dysfunction; POCD
Interventions: Drug: Precedex (Dexmedetomidine); Drug: Placebo
Sponsors: Mount Sinai School of Medicine; Mount Sinai School of Medicine; National Institute on Aging (NIA)
Recruiting - verified January 2012 - Condition: Opiate Dependence
Interventions: Behavioral: Behavioral: Buprenorphine/naloxone maintenance (Mtn); Behavioral: Behavioral: Buprenorphine/naloxone detoxification (Dtx)
Sponsors: Yale University; Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified November 2011 - Conditions: Adult Attention Deficit Hyperactivity Disorder; Cocaine Dependence
Interventions: Drug: Placebo; Drug: Adderall-XR; Drug: Adderall-XR
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2012 - Conditions: Sleep; Burns
Interventions: Drug: zolipidem; Drug: ramelteon
Sponsors: Shriners Hospitals for Children; Shriners Hospitals for Children; Children's Hospital Medical Center, Cincinnati
Recruiting - verified May 2012 - Condition: Advanced Cancer
Interventions: Drug: Valproic Acid; Drug: Bevacizumab
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center
Recruiting - verified February 2012 - Conditions: Obesity; Binge Eating
Interventions: Drug: Sibutramine; Drug: Placebo; Behavioral: Self-help CBT + Sibutramine; Behavioral: Self-help CBT + Placebo
Sponsors: Yale University; Yale University; National Institutes of Health (NIH); National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified January 2012 - Conditions: Schizophrenia; Schizoaffective Disorder; Bipolar Disorder; Obesity; Metabolic Syndrome
Intervention: Drug: olanzapine and melatonin
Sponsors: Seattle Institute for Biomedical and Clinical Research; Seattle Institute for Biomedical and Clinical Research; Eli Lilly and Company
Recruiting - verified November 2011 - Conditions: Developmental Delay Disorders; Chromosome Deletion; Mental Retardation; Sleep Disorders, Circadian Rhythm; Self Injurious Behavior
Interventions: Drug: dTR Melatonin (NIH CC PDS); Device: Phototherapy (Bright Light); Drug: Melatonin CR
Sponsors: National Institutes of Health Clinical Center (CC); National Human Genome Research Institute (NHGRI)
Recruiting - verified June 2011 - Condition: Solid Tumors
Interventions: Drug: Dasatinib; Drug: Erlotinib; Drug: Lapatinib; Drug: Lenalidomide; Drug: Sorafenib; Drug: Sunitinib; Drug: Valproic Acid
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center
Recruiting - verified December 2011 - Condition: Critically Ill Premature Neonates
Interventions: Drug: Morphine; Drug: Morphine
Sponsors: Children's Research Institute; Children's Research Institute; University of Louisville; State University of New York - Downstate Medical Center
Recruiting - verified April 2012 - Conditions: Advanced Cancer; Weight Loss
Intervention: Drug: Olanzapine
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center
Recruiting - verified May 2012 - Conditions: Extubation; Respiration Disorders
Intervention: Drug: Dexmedetomidine
Sponsors: University of California, San Francisco; University of California, San Francisco
Recruiting - verified October 2011 - Conditions: Preeclampsia; Hypotension
Interventions: Drug: Ephedrine; Drug: Phenylephrine
Sponsors: Northwestern University; Northwestern University
Recruiting - verified January 2012 - Conditions: Schizophrenia; Schizoaffective Disorder
Interventions: Drug: Olanzapine (Zyprexa); Drug: Typicals
Sponsors: VA Connecticut Healthcare System; VA Connecticut Healthcare System; Clinical Trials Network of Columbia U, Cornell U, and NY Presbyterian Hospital; Eli Lilly and Company
Recruiting - verified March 2012 - Conditions: Anxiety Disorders; Complex Regional Pain Syndrome Type II; Depressive Disorders; Post-Traumatic Stress Disorder; Substance Abuse
Intervention: Procedure: Regional Anesthesia
Sponsors: Department of Veterans Affairs; Department of Veterans Affairs; Walter Reed National Military Medical Center; Brooke Army Medical Center; United States Army Institute of Surgical Research
Recruiting - verified March 2012 - Condition: Cocaine-Related Disorders
Intervention: Procedure: acoustic startle testing
Sponsors: Emory University; Emory University; National Institute on Drug Abuse (NIDA)
Recruiting - verified March 2012 - Condition: Breast Neoplasms
Interventions: Drug: Sevoflurane; Drug: Sevoflurane
Sponsors: Outcomes Research Consortium; Outcomes Research Consortium
Recruiting - verified May 2012 - Condition: Cocaine Dependence
Interventions: Drug: Modafinil; Drug: placebo; Behavioral: Cognitive Behavioral Therapy (CBT)
Sponsors: University of Pennsylvania; University of Pennsylvania
Recruiting - verified November 2011 - Condition: Schizophrenia
Interventions: Behavioral: Cognitive remediation; Behavioral: Health behavior training; Drug: Risperidone, administered orally; Drug: Risperidone, administered via injection; Behavioral: Individual Placement and Support
Sponsors: National Institute of Mental Health (NIMH); National Institute of Mental Health (NIMH); Ortho-McNeil Janssen Scientific Affairs, LLC
Recruiting - verified October 2011 - Condition: Schizophrenia
Interventions: Behavioral: Group Skills Training and Psychoeducation; Behavioral: Individual Case Management; Drug: Oral Risperidone; Drug: Risperidone in Long-Acting Injectable Form (Consta)
Sponsors: National Institute of Mental Health (NIMH); National Institute of Mental Health (NIMH); Ortho-McNeil Janssen Scientific Affairs, LLC
Recruiting - verified October 2011 - Condition: Schizophrenia
Interventions: Drug: Aripiprazole; Drug: Risperidone; Drug: Clozapine
Sponsors: North Shore Long Island Jewish Health System; North Shore Long Island Jewish Health System; National Institute of Mental Health (NIMH)
Recruiting - verified January 2012 - Conditions: High Grade Gliomas; Brain Tumors
Interventions: Procedure: adjuvant therapy; Drug: Temozolomide; Drug: Valporic Acid; Radiation: Radiation therapy
Sponsors: National Institutes of Health Clinical Center (CC); National Cancer Institute (NCI)
Recruiting - verified March 2012 - Conditions: Cervical Cancer; Endometrial Cancer; Fallopian Tube Cancer; Ovarian Cancer; Pain; Perioperative/Postoperative Complications; Sarcoma
Interventions: Drug: fentanyl citrate; Drug: hydromorphone hydrochloride; Drug: ropivacaine hydrochloride
Sponsors: National Cancer Institute (NCI); University of California, San Francisco; National Cancer Institute (NCI)
Recruiting - verified September 2007 - Condition: Opioid-Related Disorders
Interventions: Drug: Clonidine; Drug: Placebo
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified March 2012 - Conditions: Tachycardia; Chronic Orthostatic Intolerance
Interventions: Drug: Acetazolamide; Drug: Atomoxetine; Other: Baseline (No Drug); Drug: Clonidine; Drug: Entacapone; Drug: Entacapone & Propranolol; Drug: Atomoxetine & Propranolol; Drug: Indomethacin; Drug: Mecamylamine; Drug: Isosorbide Dinitrate; Dietary Supplement: Melatonin; Drug: Midodrine; Drug: Modafinil; Drug: Octreotide; Radiation: Placebo; Drug: Propranolol; Drug: Modafinil & Propranolol; Drug: Sertraline; Procedure: IV Saline; Other: Drinking Water; Device: Breathing Device; Drug: memantine; Device: Abdominal binder
Sponsors: Vanderbilt University; Satish R. Raj; National Institutes of Health (NIH)
Recruiting - verified February 2012 - Conditions: Stress Disorders, Post-Traumatic; Alcohol Abuse; Substance-Related Disorders
Interventions: Behavioral: Seeking Safety; Drug: Sertraline, "Zoloft" and Placebo
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified October 2011 - Condition: Bipolar Disorder
Intervention: Drug: Lithium treatment
Sponsors: Department of Veterans Affairs; Department of Veterans Affairs
Recruiting - verified December 2011 - Condition: Functional Dyspepsia
Interventions: Drug: Amitriptyline; Drug: escitalopram; Drug: placebo
Sponsors: Mayo Clinic; Mayo Clinic; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified January 2012 - Conditions: Cocaine Dependence; Depression
Interventions: Drug: Mirtazapine; Drug: Placebo
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute on Drug Abuse (NIDA)
Recruiting - verified October 2011 - Conditions: Autonomic Failure; Orthostatic Hypotension
Interventions: Drug: Atomoxetine; Drug: Acarbose; Drug: Pyridostigmine Bromide; Drug: Yohimbine; Drug: Midodrine HCl; Drug: placebo; Drug: Modafinil; Drug: Octreotide; Other: water intake; Drug: Diphenhydramine Hydrochloride; Drug: Ranitidine HCL; Drug: Tranylcypromine; Drug: Ergotamine/ Caffeine; Drug: Celecoxib; Drug: Pseudoephedrine; Drug: Methylphenidate; Drug: Indomethacin; Drug: Ibuprofen; Drug: Oxymetazoline 0.05% nasal solution; Dietary Supplement: Bovril; Drug: Acetazolamide; Drug: Rivastigmine tartrate; Drug: Carbidopa/levodopa; Device: abdominal binder; Device: abdominal binder (sham)
Sponsors: Vanderbilt University; Vanderbilt University
Recruiting - verified May 2012 - Condition: Abruptio Placentae
Intervention: Drug: magnesium sulfate, Normal Saline
Sponsors: Stanford University; Stanford University
Recruiting - verified April 2012 - Condition: Schizophrenia
Interventions: Drug: Tiagabine; Drug: Placebo
Sponsors: Beth Israel Deaconess Medical Center; Beth Israel Deaconess Medical Center; Dartmouth-Hitchcock Medical Center
Recruiting - verified July 2011 - Condition: Bipolar Disorder
Intervention: Drug: abilify (aripiprazole)
Sponsors: University Hospitals of Cleveland; University Hospitals of Cleveland; Bristol-Myers Squibb
Recruiting - verified December 2011 - Conditions: Schizophrenia; Schizoaffective Disorder; Major Depression; Bipolar Disorder; Coronary Artery Disease
Interventions: Drug: Eicosapentaenoic acid (omega-3 fatty acid); Drug: Placebo
Sponsors: University of Pittsburgh; University of Pittsburgh; American Heart Association; VA Pittsburgh Healthcare System
Recruiting - verified October 2011 - Conditions: Depression; Major Depression/Bipolar Disorder
Interventions: Drug: Ketamine; Drug: Riluzole; Drug: FDG
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Mental Health (NIMH)
Recruiting - verified January 2012 - Condition: Healthy
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified September 2011 - Condition: Cerebrovascular Accident
Interventions: Drug: Magnesium Sulfate; Drug: Normal Saline
Sponsors: University of California, Los Angeles; Jeffrey L. Saver; National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified December 2011 - Condition: Alcoholism
Interventions: Drug: ondansetron + cognitive behavioral therapy; Drug: topiramate + cognitive behavioral therapy; Drug: Placebo + cognitive behavioral therapy; Drug: ondansetron + topiramate + cognitive behavioral therapy
Sponsors: University of Virginia; Bankole Johnson; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified February 2012
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Central Nervous System Depressants Clinical Trials |
