- Condition: Cigarette Smoking
Interventions: Drug: Nicotine replacement therapy - transdermal nicotine patch; Behavioral: Tailored behavioral intervention; Behavioral: Tobacco quitline referral; Drug: Nicotine replacement therapy - nicotine gum; Drug: Nicotine replacement therapy - nicotine lozenge; Drug: Bupropion SR; Drug: Varenicline; Drug: Combination pharmacotherapy - transdermal nicotine patch + nicotine gum; Drug: Combination pharmacotherapy - transdermal nicotine patch + nicotine lozenge; Drug: Combination pharmacotherapy - transdermal nicotine patch + bupropion; Behavioral: Alcohol use risk reduction; Behavioral: Behavioral activation for the treatment of depression; Behavioral: Behavioral management of post-cessation weight gain
Sponsors: University of Iowa; University of Iowa; Department of Veterans Affairs
Not yet recruiting - verified May 2012 - Conditions: Cigarette Smoking; Nicotine Dependence
Interventions: Drug: varenicline (Chantix); Drug: bupropion (Zyban) & nicotine patches; Drug: nicotine patches
Sponsors: Duke University; Duke University; Philip Morris USA, Inc.
Recruiting - verified May 2012 - Conditions: Methamphetamine Dependence; Methamphetamine Abuse; Substance Abuse
Interventions: Drug: Placebo; Drug: Varenicline; Drug: Varenicline
Sponsors: Baylor College of Medicine; Baylor College of Medicine; National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2012 - Conditions: Alcoholism; Alcohol Abuse; Smoking; Alcohol Drinking
Intervention: Drug: Varenicline
Sponsors: Yale University; Yale University; Columbia University
Not yet recruiting - verified March 2012 - Conditions: Breast Cancer; Tobacco Dependence
Interventions: Drug: placebo; Drug: varenicline
Sponsors: Memorial Sloan-Kettering Cancer Center; Memorial Sloan-Kettering Cancer Center; Pfizer
Recruiting - verified February 2012 - Condition: Nicotine Dependence
Intervention: Drug: Varenicline or placebo
Sponsors: University of Pennsylvania; University of Pennsylvania; National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)
Recruiting - verified February 2012 - Condition: Nicotine Dependence
Interventions: Drug: Varenicline; Drug: placebo
Sponsors: Medical University of South Carolina; Medical University of South Carolina
Not yet recruiting - verified December 2011 - Condition: Smoking Cessation
Interventions: Drug: Placebo; Drug: varenicline tartrate; Drug: bupropion hydrochloride; Drug: Nicotine Replacement Therapy Patch
Sponsors: Pfizer; Pfizer; GlaxoSmithKline
Recruiting - verified May 2012 - Condition: Smoking Cessation
Interventions: Behavioral: Smoking counseling; Behavioral: Smoking counseling; Drug: Placebo; Drug: Varenicline
Sponsors: University of California, San Francisco; University of California, San Francisco; Pfizer
Recruiting - verified May 2012 - Conditions: Tobacco Use Disorder; Medication Adherence
Intervention: Behavioral: Varenicline treatment as usual or directly observed therapy
Sponsors: Albert Einstein College of Medicine of Yeshiva University; Albert Einstein College of Medicine of Yeshiva University; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Condition: Nicotine Dependence
Interventions: Drug: Varenicline; Drug: Bupropion; Drug: Nicotine patches
Sponsors: Duke University; Duke University; National Institute on Drug Abuse (NIDA)
Recruiting - verified January 2012 - Condition: Smoking Cessation
Interventions: Drug: Varenicline Tartrate; Drug: Placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Conditions: Chronic Pain; Opioid Dependence
Interventions: Drug: Varenicline; Drug: Placebo
Sponsors: Mayo Clinic; Mayo Clinic
Recruiting - verified May 2012 - Conditions: Methamphetamine Dependence; Substance Abuse; Methamphetamine Abuse
Interventions: Drug: Varenicline; Drug: Placebo
Sponsors: University of California, Los Angeles; University of California, Los Angeles
Recruiting - verified March 2012 - Conditions: Smoking; Tobacco Dependence; Alcohol Dependence
Interventions: Drug: Varenicline; Drug: placebo
Sponsors: Mayo Clinic; Mayo Clinic
Recruiting - verified April 2012 - Condition: Parkinson Disease
Interventions: Drug: Varenicline; Drug: Sugar pill
Sponsors: Rush University Medical Center; Rush University Medical Center
Recruiting - verified February 2012 - Condition: Nicotine Addiction
Interventions: Drug: Varenicline; Drug: Placebo; Drug: Transdermal Nicotine
Sponsors: University of Pennsylvania; University of Pennsylvania; National Institute on Drug Abuse (NIDA)
Recruiting - verified January 2012 - Condition: Smoking Cessation
Interventions: Drug: Varenicline 1mg BID; Drug: Varenicline 0.5mg BID; Drug: Placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Condition: Drug Addiction
Intervention: Drug: Varenicline
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Not yet recruiting - verified December 2011 - Condition: Nicotine Dependence
Interventions: Drug: Varenicline; Drug: Bupropion; Drug: Nicotine patches; Drug: Nicotine Inhaler
Sponsors: Duke University; Duke University; National Institute on Drug Abuse (NIDA); Philip Morris USA, Inc.
Recruiting - verified March 2012 - Conditions: Smoking; Smoking Cessation
Interventions: Other: Coordinated Care; Other: Usual Care
Sponsors: University of Pittsburgh; University of Pittsburgh; National Institutes of Health (NIH); National Cancer Institute (NCI)
Recruiting - verified September 2011 - Condition: Smoking Cessation
Interventions: Drug: Varenicline; Drug: Placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Condition: Smoking Addiction
Interventions: Drug: Placebo; Drug: Varenicline
Sponsors: The Mind Research Network; The Mind Research Network; National Institute on Drug Abuse (NIDA)
Recruiting - verified November 2011 - Conditions: Alcohol Dependence; Cocaine Dependence
Interventions: Drug: Varenicline; Drug: Placebo
Sponsors: University of Pennsylvania; University of Pennsylvania; National Institute on Drug Abuse (NIDA)
Recruiting - verified August 2011 - Condition: Nicotine Dependence
Interventions: Drug: Varenicline; Behavioral: Individual counseling; Behavioral: Check-ins with medical staff; Behavioral: individual counseling
Sponsors: University of California, San Francisco; University of California, San Francisco; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Condition: Cocaine Dependence
Intervention: Drug: Varenicline
Sponsors: University of Pennsylvania; University of Pennsylvania; National Institute on Drug Abuse (NIDA)
Recruiting - verified August 2011 - Conditions: Schizophrenia; Smoking Cessation
Interventions: Other: Sugar Pill; Drug: Varenicline; Drug: Bupropion HCl
Sponsors: University of Minnesota - Clinical and Translational Science Institute; University of Minnesota - Clinical and Translational Science Institute; National Institutes of Health (NIH); National Institute on Drug Abuse (NIDA)
Recruiting - verified August 2011 - Conditions: Head and Neck Cancer; Smoking Cessation
Interventions: Behavioral: Acceptance and Commitment Therapy; Behavioral: Motivational and Behavioral Counseling; Drug: Varenicline
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center
Recruiting - verified April 2012 - Conditions: Smoking Cessation; Depression
Interventions: Drug: varenicline; Drug: placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Condition: Alcohol Reactivity
Interventions: Drug: varenicline; Drug: placebo
Sponsors: Yale University; Yale University
Recruiting - verified January 2012 - Condition: Smoking Cessation
Interventions: Drug: Varenicline; Drug: Bupropion; Other: Placebo; Behavioral: Counseling/Phone Calls
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center; National Institutes of Health (NIH); National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2012 - Conditions: Cigarette Smoking; Nicotine Dependence; Post-traumatic Stress Disorder; Tobacco Use Disorder
Interventions: Drug: Varenicline; Behavioral: Medication Management Counseling; Behavioral: Prolonged Exposure
Sponsors: University of Pennsylvania; University of Pennsylvania; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Conditions: Nicotine Dependence; Smoking Cessation
Interventions: Other: Varenicline and smoking cessation counseling; Behavioral: Exercise or relaxation treatment
Sponsors: University of Connecticut Health Center; University of Connecticut Health Center; National Institutes of Health (NIH); National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2012 - Conditions: Cigarette Smoking; Hypertension
Interventions: Drug: Varenicline; Behavioral: behavioral therapy
Sponsors: University of Connecticut Health Center; University of Connecticut Health Center; National Institute on Drug Abuse (NIDA)
Recruiting - verified December 2011 - Conditions: Schizophrenia; Cigarette Smoking
Interventions: Drug: Varenicline; Drug: Placebo for varenicline
Sponsors: Nathan Kline Institute for Psychiatric Research; Nathan Kline Institute for Psychiatric Research
Recruiting - verified May 2012 - Conditions: Bladder Cancer; Cervical Cancer; Esophageal Cancer; Gastric Cancer; Head and Neck Cancer; Kidney Cancer; Leukemia; Liver Cancer; Lung Cancer; Pancreatic Cancer; Tobacco Use Disorder
Interventions: Drug: nicotine; Drug: varenicline; Other: placebo
Sponsors: Butler Hospital; Butler Hospital; National Cancer Institute (NCI)
Recruiting - verified March 2012 - Condition: Smoking
Interventions: Drug: naltrexone; Drug: varenicline; Drug: placebo
Sponsors: Yale University; Yale University
Recruiting - verified January 2012 - Conditions: Smoking Cessation; Nicotine Dependence
Interventions: Drug: Nicotine Replacement Treatment (NRT); Drug: varenicline; Behavioral: Behavioral counseling for smoking cessation; Drug: Placebo patch; Drug: Placebo
Sponsors: Brown University; Brown University; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2009 - Conditions: Smoking; HIV Infections
Interventions: Drug: Varenicline tartrate; Drug: Nicotine Replacement Therapy; Other: Biological Control; Behavioral: Motivational Interview
Sponsors: Ohio State University; Ohio State University; National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified August 2011 - Condition: Alcohol Drinking
Interventions: Drug: Varenicline; Drug: Varenicline (Chantix)
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified November 2011 - Condition: Nicotine Dependence
Interventions: Drug: varenicline; Device: transdermal nicotine patch
Sponsors: Medical University of South Carolina; Medical University of South Carolina
Recruiting - verified July 2010 - Condition: Alcohol Drinking
Interventions: Drug: varenicline; Drug: bupropion; Drug: placebo
Sponsors: Yale University; Yale University
Recruiting - verified January 2012 - Condition: Smoking Lapse Behavior
Interventions: Drug: varenicline; Drug: bupropion; Drug: Placebo
Sponsors: Yale University; Yale University
Recruiting - verified January 2012


