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Chlorhexidine

Chlorhexidine

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  • Persistent Methicillin Resistant Staphylococcus Aureus Eradication Protocol (PMEP)

    Condition:   Cystic Fibrosis
    Interventions:   Drug: Inhaled Vancomycin;   Drug: Placebo (Sterile Water);   Drug: Rifampin;   Drug: Trimethoprim/Sulfamethoxazole (TMP/SMX);   Drug: Doxycycline;   Drug: Mupirocin Nasal Ointment;   Drug: 4% chlorhexidine gluconate liquid skin cleanser
    Sponsors:   Johns Hopkins University;   Michael Boyle;   Case Western Reserve University;   Cystic Fibrosis Foundation
    Not yet recruiting - verified May 2012
  • Role of Infected Blood Dendritic Cells in Heart Disease Risk

    Condition:   Chronic Periodontitis
    Interventions:   Drug: Amoxicillin-Metronidazole combination plus oral rinse;   Device: scaling and root planing
    Sponsors:   Georgia Health Sciences University;   Georgia Health Sciences University;   National Institute of Dental and Craniofacial Research (NIDCR)
    Recruiting - verified April 2012
  • Superficial Cervical Plexus Block for Shoulder Pain After Lung Surgery

    Condition:   Shoulder Pain
    Interventions:   Procedure: Superficial Cervical Plexus Block;   Drug: Bupivacaine
    Sponsors:   University of Washington;   University of Washington
    Not yet recruiting - verified March 2012
  • Evaluation of a Staphylococcus Eradication Protocol for Patients Who Present to the Emergency Department With Cutaneous Abscess

    Condition:   Cutaneous Abscess
    Interventions:   Drug: Chlorhexidine gluconate;   Drug: Mupirocin
    Sponsors:   Tufts Medical Center;   Tufts Medical Center
    Recruiting - verified March 2012
  • Study of the 532 nm KTP Laser for the Treatment of Poikiloderma of Civatte

    Conditions:   Poikiloderma of Civatte;   Dyschromia;   Pigmentation Disorders;   Telangiectasia;   Photosensitivity Disorders
    Intervention:   Device: 532 nm KTP laser
    Sponsors:   Cutera Inc.;   Cutera Inc.
    Recruiting - verified December 2011
  • Prevention of Post-operative Pneumonia (POPP)

    Conditions:   Post-operative Pneumonia;   Lung Cancer;   Esophageal Cancer
    Intervention:   Procedure: Intensive Brushing Regimen
    Sponsors:   Washington University School of Medicine;   Washington University School of Medicine
    Recruiting - verified October 2011
  • The Skin Prep Study

    Condition:   Surgical Site Infections
    Interventions:   Drug: Iodine-alcohol;   Drug: Chlorhexidine-alcohol
    Sponsors:   Washington University School of Medicine;   Washington University School of Medicine
    Recruiting - verified November 2011
  • Eliminate Risk of Cardiac Surgical Site Events

    Condition:   Surgical Site Infections
    Interventions:   Other: 2% Chlorhexidine Gluconate cloths;   Other: Standard of Care preoperative preparation.
    Sponsors:   University of Rochester;   University of Rochester;   Sage Products, Inc.
    Recruiting - verified December 2011
  • Multicenter Blood Culture Quality Improvement

    Condition:   Bacteremia
    Intervention:   Other: Blood Culture QI Program
    Sponsors:   Vanderbilt University;   Vanderbilt University;   Community Health Systems;   Society for Academic Emergency Medicine;   CareFusion;   Trinity Medical Center, Birmingham;   Carolinas Hospital System;   Dyersburg Regional Hospital;   Gateway Medical Center;   Crestwood Medical Center;   Jackson Regional Hospital
    Recruiting - verified August 2011
  • Post-Operative Colonization Rates of Femoral Nerve Catheters Treated With Chlorhexidine-Impregnated Patch

    Conditions:   Catheter Infections;   Spinal Catheter (Epidural) (Subdural); Complications, Infection or Inflammation
    Intervention:   Device: Chlorhexidine impregnated patch (Biopatch)
    Sponsors:   University of Wisconsin, Madison;   University of Wisconsin, Madison
    Recruiting - verified August 2011
  • Early Methicillin-resistant Staphylococcus Aureus (MRSA) Therapy in Cystic Fibrosis (CF)

    Conditions:   Cystic Fibrosis;   Methicillin-resistant Staphylococcus Aureus
    Interventions:   Drug: Rifampin;   Drug: Trimethoprim/Sulfamethoxazole;   Drug: Minocycline;   Drug: Mupirocin;   Drug: chlorhexidine gluconate oral rinse;   Drug: 2% Chlorhexidine solution wipes;   Behavioral: Environmental Decontamination
    Sponsors:   University of North Carolina, Chapel Hill;   University of North Carolina, Chapel Hill;   CF Therapeutics Development Network Coordinating Center;   Seattle Children's Hospital;   University of Washington;   University of Colorado, Denver;   Texas Children's Hospital;   University of Alabama at Birmingham;   St. Louis Children's Hospital;   Cook Children's Medical Center;   University of Michigan Health System
    Recruiting - verified January 2012
  • Trial of Drain Antisepsis After Tissue Expander Breast Reconstruction

    Conditions:   Nonmalignant Breast Conditions;   Breast Cancer
    Interventions:   Device: sodium hypochlorite (Dakins Soln);   Drug: Chlorhexidine gluconate disk
    Sponsors:   Mayo Clinic;   Mayo Clinic;   University of California, San Francisco
    Recruiting - verified April 2012
  • A Comparison of Infection Rates Between Two Surgical Sites

    Conditions:   Corneal Toxicity;   Ototoxicity;   Surgical Site Infection
    Intervention:  
    Sponsors:   Mayo Clinic;   Mayo Clinic
    Recruiting - verified July 2011
  • Botulinum Toxin A for Herpes Labialis

    Condition:   Herpes Labialis
    Interventions:   Drug: onabotulinumtoxinA;   Other: Bacteriostatic normal saline
    Sponsors:   DeNova Research;   DeNova Research;   Allergan
    Recruiting - verified June 2011
  • The Effect Of Wound Irrigation With Irrisept™ Delivery System On Abscess Healing In Patients Presenting To The Emergency Department

    Condition:   Abscess
    Intervention:   Device: Irrisept
    Sponsors:   University of Florida;   University of Florida;   Irrimax Corporation
    Recruiting - verified March 2012
  • EXCEL Clinical Trial

    Conditions:   Chronic Coronary Occlusion;   Unprotected Left Main Coronary Artery Disease;   Stent Thrombosis;   Vascular Disease;   Myocardial Ischemia;   Coronary Artery Stenosis;   Coronary Disease;   Coronary Artery Disease;   Coronary Restenosis
    Interventions:   Device: Percutaneous Coronary Intervention;   Procedure: CABG
    Sponsors:   Abbott Vascular;   Abbott Vascular
    Recruiting - verified April 2012
  • EXCEL Clinical Trial (Universal Registry)

    Conditions:   Chronic Coronary Occlusion;   Left Main Coronary Artery Disease;   Stent Thrombosis;   Vascular Disease;   Myocardial Ischemia;   Coronary Artery Stenosis;   Coronary Disease;   Coronary Artery Disease;   Coronary Restenosis
    Intervention:  
    Sponsors:   Abbott Vascular;   Abbott Vascular
    Recruiting - verified April 2012
  • ChloraPrep Versus Betadine for Elective Knee Replacement Surgery

    Conditions:   Arthroplasty, Knee Replacement;   Replacement, Total Knee;   Total Knee Replacement
    Interventions:   Drug: Swab area with Betadine;   Drug: Swab area with ChloraPrep
    Sponsors:   Central DuPage Hospital;   Central DuPage Hospital
    Recruiting - verified February 2012
  • CAMBRA - PBRN Caries Management By Risk Assessment In A Practice-Based Research Network

    Condition:   Dental Caries
    Interventions:   Other: active treatment caries preventive measures;   Other: control treatment
    Sponsors:   University of California, San Francisco;   University of California, San Francisco;   California Dental Association Foundation
    Recruiting - verified May 2012
  • Evaluating Strategies to Prevent Methicillin-resistant Staphylococcus Aureus Skin and Soft Tissue Infections in Military Trainees

    Conditions:   Staphylococcus Aureus;   Community-associated MRSA Infections;   Staphylococcal Skin Infections
    Interventions:   Drug: Chlorhexidine gluconate;   Other: Standardized training and education
    Sponsors:   Uniformed Services University of the Health Sciences;   Uniformed Services University of the Health Sciences;   Centers for Disease Control and Prevention
    Recruiting - verified July 2011
  • Diabetes and Periodontal Therapy Trial

    Conditions:   Chronic Periodontitis;   Type 2 Diabetes
    Interventions:   Procedure: Non-surgical periodontal treatment;   Other: Delayed non-surgical periodontal therapy
    Sponsors:   Stony Brook University;   Stony Brook University;   University of Alabama at Birmingham;   University of Minnesota - Clinical and Translational Science Institute;   The University of Texas Health Science Center, Houston;   University of Texas;   National Institute of Dental and Craniofacial Research (NIDCR)
    Recruiting - verified December 2011
  • A Trial to Reduce Pneumonia in Nursing Home Residents

    Conditions:   Pneumonia;   Lower Respiratory Tract Infection
    Interventions:   Other: Enhanced Oral Care;   Other: Usual oral care
    Sponsors:   Yale University;   Yale University;   National Institute on Aging (NIA)
    Recruiting - verified May 2012

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