- Condition: Stress Symptomatology
Interventions: Behavioral: Progressive Muscle Relaxation; Behavioral: Coherence Advantage
Sponsors: United States Naval Medical Center, San Diego; United States Naval Medical Center, San Diego
Recruiting - verified May 2012 - Conditions: Hyperhydrosis; Depression
Intervention: Drug: Glycopyrrolate
Sponsors: Thomas Jefferson University; Thomas Jefferson University
Recruiting - verified April 2012 - Condition: Chronic Obstructive Pulmonary Disease
Interventions: Drug: PT003; Drug: PT001; Drug: PT005; Drug: Tiotropium inhalation powder
Sponsors: Pearl Therapeutics, Inc.; Pearl Therapeutics, Inc.
Recruiting - verified April 2012 - Condition: Amblyopia
Interventions: Drug: Placebo; Drug: Donepezil; Other: Patching
Sponsors: Children's Hospital Boston; Children's Hospital Boston
Recruiting - verified April 2012 - Condition: Cigarette Smoking
Interventions: Drug: Nicotine replacement therapy - transdermal nicotine patch; Behavioral: Tailored behavioral intervention; Behavioral: Tobacco quitline referral; Drug: Nicotine replacement therapy - nicotine gum; Drug: Nicotine replacement therapy - nicotine lozenge; Drug: Bupropion SR; Drug: Varenicline; Drug: Combination pharmacotherapy - transdermal nicotine patch + nicotine gum; Drug: Combination pharmacotherapy - transdermal nicotine patch + nicotine lozenge; Drug: Combination pharmacotherapy - transdermal nicotine patch + bupropion; Behavioral: Alcohol use risk reduction; Behavioral: Behavioral activation for the treatment of depression; Behavioral: Behavioral management of post-cessation weight gain
Sponsors: University of Iowa; University of Iowa; Department of Veterans Affairs
Not yet recruiting - verified May 2012 - Condition: Nicotine Dependence
Intervention: Drug: Intravenous Nicotine
Sponsors: Mclean Hospital; Mclean Hospital; National Institute on Drug Abuse (NIDA)
Recruiting - verified May 2012 - Condition: Parkinson's Disease
Intervention:
Sponsors: University of Michigan; University of Michigan
Recruiting - verified May 2012 - Conditions: Depressive Disorder; Depressive Disorder, Major; Depression
Intervention: Other: Citalopram
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Mental Health (NIMH)
Recruiting - verified March 2012 - Conditions: Cigarette Smoking; Nicotine Dependence
Interventions: Drug: varenicline (Chantix); Drug: bupropion (Zyban) & nicotine patches; Drug: nicotine patches
Sponsors: Duke University; Duke University; Philip Morris USA, Inc.
Recruiting - verified May 2012 - Condition: Pulmonary Disease, Chronic Obstructive
Interventions: Drug: tiotropium; Drug: tiotropium; Drug: olodaterol; Drug: olodaterol; Drug: olodaterol; Drug: tiotropium; Drug: tiotropium; Drug: olodaterol; Drug: tiotropium
Sponsors: Boehringer Ingelheim Pharmaceuticals; Boehringer Ingelheim Pharmaceuticals
Recruiting - verified May 2012 - Condition: Nicotine Dependence
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Condition: Urge Urinary Incontinence
Intervention: Drug: solifenacin succinate
Sponsors: Loyola University; Loyola University; Astellas Pharma US, Inc.
Recruiting - verified April 2012 - Condition: Parkinson's Disease
Intervention: Drug: nicotine transdermal patch
Sponsors: University of Vermont; James BOYD MD; Michael J. Fox Foundation for Parkinson's Research
Not yet recruiting - verified March 2012 - Conditions: MDD; Citalopram; Major Depressive Disorder
Intervention: Drug: citalopram
Sponsors: Mclean Hospital; Mclean Hospital
Recruiting - verified April 2012 - Condition: Alzheimer's Disease
Interventions: Drug: ABT-126; Drug: ABT-126; Drug: placebo
Sponsors: Abbott; Abbott
Recruiting - verified March 2012 - Condition: Nicotine Addiction
Intervention: Drug: Galantamine ER
Sponsors: University of Pennsylvania; University of Pennsylvania
Recruiting - verified March 2012 - Condition: Pulmonary Disease, Chronic Obstructive
Interventions: Drug: PH-797804; Drug: PH-797804; Drug: PH-797804; Drug: PH-797804; Drug: PH-797804; Drug: Placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Condition: Smoking Cessation
Interventions: Behavioral: WEB; Behavioral: Social Network; Behavioral: Nicotine Replacement Therapy (NRT)
Sponsors: American Legacy Foundation; American Legacy Foundation; National Cancer Institute (NCI)
Recruiting - verified March 2012 - Conditions: Alcoholism; Alcohol Abuse; Smoking; Alcohol Drinking
Intervention: Drug: Varenicline
Sponsors: Yale University; Yale University; Columbia University
Not yet recruiting - verified March 2012 - Conditions: Methamphetamine Dependence; Methamphetamine Abuse; Substance Abuse
Interventions: Drug: Placebo; Drug: Varenicline; Drug: Varenicline
Sponsors: Baylor College of Medicine; Baylor College of Medicine; National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2012 - Conditions: Asthma; Atopy
Interventions: Biological: Standardized Cat Allergen Extract and Standardized Dust Mite Allergen; Radiation: CT imaging, functional PET imaging; Drug: Nebulized methacholine inhalation
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting - verified March 2012 - Condition: Pulmonary Disease, Chronic Obstructive
Interventions: Drug: Tiotropium; Drug: Olodaterol; Drug: Tiotropium; Drug: tiotropium + olodaterol; Drug: Olodaterol; Drug: Olodaterol; Drug: tiotropium
Sponsors: Boehringer Ingelheim Pharmaceuticals; Boehringer Ingelheim Pharmaceuticals
Recruiting - verified May 2012 - Condition: Pulmonary Disease, Chronic Obstructive
Interventions: Drug: tiotropium; Drug: olodaterol; Drug: olodaterol; Drug: Tiotropium; Drug: Tiotropium; Drug: Oldaterol; Drug: Tiotropium + olodaterol
Sponsors: Boehringer Ingelheim Pharmaceuticals; Boehringer Ingelheim Pharmaceuticals
Recruiting - verified May 2012 - Condition: Drug Induced Constipation
Interventions: Drug: Nektar 118; Drug: Quinidine; Drug: Quinidine placebo; Drug: Morphine
Sponsors: AstraZeneca; AstraZeneca
Recruiting - verified March 2012 - Conditions: Breast Cancer; Tobacco Dependence
Interventions: Drug: placebo; Drug: varenicline
Sponsors: Memorial Sloan-Kettering Cancer Center; Memorial Sloan-Kettering Cancer Center; Pfizer
Recruiting - verified February 2012 - Conditions: Hot Flashes; Breast Cancer
Interventions: Drug: solifenacin; Drug: Clonidine
Sponsors: University of Arkansas; University of Arkansas
Recruiting - verified February 2012 - Condition: Pulmonary Disease, Chronic Obstructive
Interventions: Drug: tiotropium+olodaterol; Drug: tiotropium + olodaterol (high dose); Drug: placebo to tiotropium+olodaterol
Sponsors: Boehringer Ingelheim Pharmaceuticals; Boehringer Ingelheim Pharmaceuticals
Recruiting - verified May 2012 - Condition: Spinal Cord Injury
Interventions: Drug: escitalopram oxalate; Drug: Cyproheptadine; Drug: sugar pill; Other: Graded intensity exercise
Sponsors: Rehabilitation Institute of Chicago; T. George Hornby; University of Medicine and Dentistry New Jersey; Rehabilitation Institute of Chicago
Recruiting - verified February 2012 - Condition: Tobacco Use Disorder
Intervention: Drug: Nicotine lozenge 4 mg
Sponsors: University of Minnesota - Clinical and Translational Science Institute; University of Minnesota - Clinical and Translational Science Institute; National Institute on Drug Abuse (NIDA)
Recruiting - verified January 2012 - Condition: Nicotine Dependence
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified November 2011 - Condition: Nicotine Dependence
Intervention: Drug: Varenicline or placebo
Sponsors: University of Pennsylvania; University of Pennsylvania; National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)
Recruiting - verified February 2012 - Condition: Parkinson's Disease
Intervention: Drug: Donepezil
Sponsors: Oregon Health and Science University; Oregon Health and Science University
Recruiting - verified January 2012 - Conditions: Parkinson's Disease; Mild Cognitive Impairment
Interventions: Drug: Exelon Patch (rivastigmine transdermal system); Drug: Placebo Patches
Sponsors: University of Pennsylvania; University of Pennsylvania
Recruiting - verified January 2012 - Condition: Nicotine Dependence
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified October 2011 - Condition: Smoking
Interventions: Other: Very low level nicotine containing cigarette; Other: Low nicotine level cigarette; Other: Moderate level nicotine cigarette
Sponsors: Masonic Cancer Center, University of Minnesota; Masonic Cancer Center, University of Minnesota
Recruiting - verified May 2012 - Condition: Psychosocial Problem
Interventions: Behavioral: Health Education; Behavioral: Questionnaires; Behavioral: Telephone Counseling Sessions; Drug: Nicotine Patches
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center; National Institutes of Health (NIH)
Recruiting - verified January 2012 - Condition: Smoking Cessation
Interventions: Behavioral: Telephone counseling; Drug: Nicotine-replacement therapy (patches); Behavioral: Monetary incentives
Sponsors: University of California, San Diego; University of California, San Diego; University of California, San Francisco; Centers for Medicare and Medicaid Services; California Department of Health Services
Not yet recruiting - verified December 2011 - Conditions: Overactive Bladder; Overactive Urinary Bladder
Interventions: Drug: MK-4618; Drug: Tolterodine ER; Drug: MK-1468 and Tolterodine ER; Other: Placebo (MK-4618); Other: Placebo (Tolterodine ER); Drug: Prophylactic Antibiotic
Sponsors: Merck; Merck
Recruiting - verified February 2012 - Condition: Nicotine Dependence
Interventions: Drug: Varenicline; Drug: placebo
Sponsors: Medical University of South Carolina; Medical University of South Carolina
Not yet recruiting - verified December 2011 - Condition: Cocaine Use Disorders
Interventions: Drug: High-dose donepezil; Drug: Low-dose donepezil; Drug: Selegiline; Drug: Placebo
Sponsors: Midwest Biomedical Research Foundation; Midwest Biomedical Research Foundation; National Institute on Drug Abuse (NIDA)
Recruiting - verified May 2012 - Condition: Nicotine Addiction
Interventions: Drug: Saline; Drug: Nicotine
Sponsors: Yale University; Yale University
Recruiting - verified December 2011 - Condition: Addiction
Interventions: Drug: Galantamine; Drug: Placebo
Sponsors: Yale University; Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Condition: Pulmonary Disease, Chronic Obstructive
Interventions: Drug: tiotropium; Drug: Placebo
Sponsors: Boehringer Ingelheim Pharmaceuticals; Boehringer Ingelheim Pharmaceuticals
Recruiting - verified May 2012 - Condition: Cigarette Smoking
Interventions: Behavioral: contingency management for smoking abstinence; Drug: transdermal nicotine; Behavioral: Telephone counseling
Sponsors: University of Connecticut Health Center; University of Connecticut Health Center; National Institute on Drug Abuse (NIDA)
Recruiting - verified March 2012 - Conditions: Nicotine Dependence; Smoking Cessation
Interventions: Drug: EVP-6124; Drug: Placebo Capsule; Drug: NicoDerm CQ Patch (Active); Drug: NRT Patch (Placebo); Behavioral: Brief Supportive and Behavioral Treatment
Sponsors: Massachusetts General Hospital; A. Eden Evins; EnVivo Pharmaceuticals, Inc.; National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2012 - Condition: Surgical Procedures, Elective
Interventions: Drug: Sugammadex; Drug: Neostigmine; Drug: Glycopyrrolate
Sponsors: Schering-Plough; Schering-Plough
Recruiting - verified May 2012 - Condition: Major Depressive Disorder
Interventions: Drug: Placebo; Drug: Vilazodone; Drug: Vilazodone; Drug: Citalopram
Sponsors: Forest Laboratories; Forest Laboratories
Recruiting - verified March 2012 - Condition: Smoking Cessation
Interventions: Other: standard care; Other: standard care plus contingency management
Sponsors: Yale University; Yale University
Recruiting - verified April 2012 - Conditions: Postvoid Dribbling; Incontinence; Post Micturition Dribble
Intervention: Drug: solifenacin
Sponsors: University of Wisconsin, Madison; University of Wisconsin, Madison
Recruiting - verified November 2011 - Condition: Alzheimer's Disease
Interventions: Drug: Donepezil; Drug: AZD3480
Sponsors: Targacept Inc.; Targacept Inc.
Recruiting - verified May 2012 - Condition: Depressive Disorder, Major
Interventions: Drug: LY2216684; Drug: Quinidine
Sponsors: Eli Lilly and Company; Eli Lilly and Company
Recruiting - verified April 2012 - Condition: Cocaine Dependence
Interventions: Drug: Citalopram; Drug: Citalopram; Drug: Placebo
Sponsors: The University of Texas Health Science Center, Houston; Joy Schmitz; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Condition: Lower Urinary Tract Symptoms
Intervention: Drug: Solifenacin (Vesicare) 5 mg orally at the same time.
Sponsors: The Methodist Hospital System; The Methodist Hospital System; Astellas Pharma US, Inc.
Recruiting - verified October 2011 - Condition: Smoking Cessation
Interventions: Drug: Placebo; Drug: varenicline tartrate; Drug: bupropion hydrochloride; Drug: Nicotine Replacement Therapy Patch
Sponsors: Pfizer; Pfizer; GlaxoSmithKline
Recruiting - verified May 2012 - Condition: Smoking
Intervention: Behavioral: Behavior smoking cessation counseling with nicotine patch
Sponsors: Brown University; Brown University; National Cancer Institute (NCI)
Recruiting - verified October 2011 - Condition: Smoking Cessation
Interventions: Drug: Meclizine; Drug: Nicotine patches
Sponsors: Duke University; Duke University; Philip Morris USA, Inc.
Recruiting - verified March 2012 - Condition: Bipolar Depression
Interventions: Drug: ESC + CBX; Drug: ESC + PBO.; Drug: ESC+CBX
Sponsors: Loyola University; Loyola University; Stanley Medical Research Institute
Recruiting - verified December 2011 - Condition: Pulmonary Disease, Chronic Obstructive
Interventions: Drug: tiotropium + olodaterol; Drug: tiotropium; Drug: tiotropium; Drug: olodaterol
Sponsors: Boehringer Ingelheim Pharmaceuticals; Boehringer Ingelheim Pharmaceuticals
Recruiting - verified May 2012 - Condition: Pulmonary Disease, Chronic Obstructive
Interventions: Drug: tiotropium; Drug: olodaterol; Drug: tiotropium; Drug: tiotropium + olodaterol
Sponsors: Boehringer Ingelheim Pharmaceuticals; Boehringer Ingelheim Pharmaceuticals
Recruiting - verified May 2012 - Condition: Cigarette Smoking
Interventions: Drug: Transdermal Nicotine Patch; Drug: Transdermal Placebo Patch
Sponsors: Brentwood Biomedical Research Institute; Brentwood Biomedical Research Institute
Not yet recruiting - verified February 2012 - Condition: Major Depressive Disorder
Intervention: Drug: Escitalopram
Sponsors: Wyss Institute at Harvard University; Wyss Institute at Harvard University; Massachusetts General Hospital; Martinos Center for Biomedical Imaging; Massachusetts Institute of Technology
Recruiting - verified April 2012 - Conditions: Posttraumatic Stress Disorder; Traumatic Brain Injury
Interventions: Drug: Methylphenidate Hydrochloride 20 mg; Drug: Placebo Capsule; Drug: Galantamine 12 mg
Sponsors: INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium; INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium; U.S. Army Medical Research and Materiel Command
Recruiting - verified January 2012 - Condition: Type 2 Diabetes Mellitus
Interventions: Drug: Placebo; Drug: Bethanechol (25 mg); Drug: Bethanechol (50 mg); Drug: Bethanechol (100 mg)
Sponsors: Washington University School of Medicine; Washington University School of Medicine; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified February 2012 - Condition: Heart Failure
Intervention: Drug: Pyridostigmine Bromide
Sponsors: New York University School of Medicine; New York University School of Medicine; Nathan Kline Institute for Psychiatric Research; Oklahoma State University Center for Health Sciences; National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting - verified August 2011 - Condition: Nicotine Dependence
Intervention:
Sponsors: Medical University of South Carolina; Medical University of South Carolina
Recruiting - verified July 2011 - Condition: Smoking Cessation
Interventions: Behavioral: Smoking counseling; Behavioral: Smoking counseling; Drug: Placebo; Drug: Varenicline
Sponsors: University of California, San Francisco; University of California, San Francisco; Pfizer
Recruiting - verified May 2012 - Condition: Cocaine Dependence
Interventions: Drug: Oral tacrine; Drug: Oral placebo
Sponsors: Midwest Biomedical Research Foundation; Midwest Biomedical Research Foundation
Not yet recruiting - verified May 2012 - Condition: Body Dysmorphic Disorder
Intervention: Procedure: PET scan and MRI scan
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified January 2012 - Conditions: Heroin Dependence; Nicotine Dependence
Interventions: Drug: Pioglitazone; Drug: Placebo
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute on Drug Abuse (NIDA); Omeros Corporation
Recruiting - verified July 2011 - Condition: Cholinergic Function
Interventions: Drug: Scopolamine; Drug: Placebo; Drug: Donepezil
Sponsors: Hebrew Rehabilitation Center, Boston; Hebrew Rehabilitation Center, Boston
Recruiting - verified March 2012 - Conditions: Tobacco Use Disorder; Medication Adherence
Intervention: Behavioral: Varenicline treatment as usual or directly observed therapy
Sponsors: Albert Einstein College of Medicine of Yeshiva University; Albert Einstein College of Medicine of Yeshiva University; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Condition: Nicotine Dependence
Interventions: Drug: Varenicline; Drug: Bupropion; Drug: Nicotine patches
Sponsors: Duke University; Duke University; National Institute on Drug Abuse (NIDA)
Recruiting - verified January 2012 - Conditions: Mild Cognitive Disorder; Mild Cognitive Impairment
Interventions: Drug: Exelon [rivastigmine] transdermal patch; Drug: Placebo patch
Sponsors: The Cleveland Clinic; The Cleveland Clinic
Recruiting - verified May 2012 - Condition: Urinary Incontinence
Interventions: Drug: solifenacin succinate; Drug: Placebo
Sponsors: Astellas Pharma Inc; Astellas Pharma Inc
Recruiting - verified March 2012 - Conditions: Cigarette Smoking; Drug Use
Interventions: Behavioral: Standard Treatment; Behavioral: BAD-AS; Drug: Transdermal Nicotine Patch
Sponsors: University of Maryland; University of Maryland; American Cancer Society
Recruiting - verified July 2011 - Condition: Smoking Cessation
Interventions: Drug: Varenicline Tartrate; Drug: Placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Condition: Sialorrhoea
Interventions: Drug: OC oral solution treatment A; Drug: OC oral solution treatment B; Drug: OC oral solution treatment C; Drug: OC oral solution treatment D
Sponsors: Orient Pharma Co., Ltd.; Orient Pharma Co., Ltd.
Recruiting - verified May 2012 - Condition: Depression
Interventions: Drug: Duloxetine; Drug: Escitalopram; Drug: BMS-820836 Placebo; Drug: BMS-820836; Drug: BMS-820836; Drug: BMS-820836; Drug: BMS-820836
Sponsors: Bristol-Myers Squibb; Bristol-Myers Squibb
Recruiting - verified August 2011 - Condition: Nicotine Dependence
Interventions: Behavioral: Standard treatment; Behavioral: Standard treatment+practice quitting
Sponsors: Rutgers University; Rutgers University; National Institute on Drug Abuse (NIDA)
Recruiting - verified June 2011 - Conditions: Orthostatic Hypotension; Multiple System Atrophy
Interventions: Drug: Droxidopa; Drug: Pyridostigmine Bromide
Sponsors: Mayo Clinic; Mayo Clinic
Recruiting - verified December 2011 - Conditions: Chronic Pain; Opioid Dependence
Interventions: Drug: Varenicline; Drug: Placebo
Sponsors: Mayo Clinic; Mayo Clinic
Recruiting - verified May 2012 - Conditions: TBI; Major Depression; Other Psychiatric Disorders
Intervention: Drug: Escitalopram
Sponsors: Johns Hopkins University; Johns Hopkins University; Forest Laboratories
Recruiting - verified February 2009 - Condition: Treatment Outcome
Interventions: Drug: Lu AA21004; Drug: Escitalopram
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Global Research & Development Center, Inc.
Recruiting - verified May 2012 - Conditions: Methamphetamine Dependence; Substance Abuse; Methamphetamine Abuse
Interventions: Drug: Varenicline; Drug: Placebo
Sponsors: University of California, Los Angeles; University of California, Los Angeles
Recruiting - verified March 2012 - Conditions: Dementia; Alzheimer's Disease
Interventions: Drug: Donepezil; Drug: Galantamine; Drug: Rivastigmine
Sponsors: Regenstrief Institute, IU Center for Aging Research; Regenstrief Institute, IU Center for Aging Research; Agency for Healthcare Research and Quality (AHRQ)
Recruiting - verified June 2011 - Condition: Cigarette Smoking Behavior
Intervention: Drug: Nicotine polacrilex
Sponsors: University of California, Los Angeles; University of California, Los Angeles; Philip Morris Products S.A.
Not yet recruiting - verified June 2011 - Condition: Smoking
Intervention: Drug: Transdermal Nicotine Patch
Sponsors: University of Maryland; University of Maryland; National Institutes of Health (NIH); National Institute on Drug Abuse (NIDA)
Recruiting - verified June 2011 - Conditions: Smoking; Tobacco Dependence; Alcohol Dependence
Interventions: Drug: Varenicline; Drug: placebo
Sponsors: Mayo Clinic; Mayo Clinic
Recruiting - verified April 2012 - Condition: Smokeless Tobacco Cessation
Interventions: Drug: Commit® nicotine lozenges (4 mg).; Behavioral: Phone Counseling; Behavioral: Self-help materials
Sponsors: Oregon Research Institute; Oregon Research Institute; National Cancer Institute (NCI); Mayo Clinic
Recruiting - verified January 2012 - Condition: Parkinson Disease
Interventions: Drug: Varenicline; Drug: Sugar pill
Sponsors: Rush University Medical Center; Rush University Medical Center
Recruiting - verified February 2012 - Condition: Parkinson's Disease
Interventions: Drug: Strattera; Drug: Exelon; Other: Placebo
Sponsors: Oregon Health and Science University; Oregon Health and Science University; National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified February 2012 - Condition: Healthy
Interventions: Drug: CW 002; Drug: CW 002; Drug: CW 002
Sponsors: Weill Medical College of Cornell University; Weill Medical College of Cornell University
Recruiting - verified June 2011 - Condition: Marijuana Dependence
Interventions: Drug: Nicotine; Drug: Placebo Patch
Sponsors: Southern Illinois University Carbondale; Southern Illinois University Carbondale; National Institute on Drug Abuse (NIDA)
Recruiting - verified March 2012 - Condition: Urinary Bladder, Overactive
Interventions: Drug: MK-4618 low-dose; Drug: MK-4618 mid-low dose; Drug: MK-4618 mid-high dose; Drug: tolterodine ER; Drug: Placebo for MK-4618; Drug: Placebo for tolterodine ER; Drug: MK-4618 high dose
Sponsors: Merck; Merck
Recruiting - verified May 2012 - Condition: Nicotine Addiction
Interventions: Drug: Varenicline; Drug: Placebo; Drug: Transdermal Nicotine
Sponsors: University of Pennsylvania; University of Pennsylvania; National Institute on Drug Abuse (NIDA)
Recruiting - verified January 2012 - Condition: Smoking Cessation
Interventions: Drug: Varenicline 1mg BID; Drug: Varenicline 0.5mg BID; Drug: Placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Condition: Major Depressive Disorder
Interventions: Drug: PNB01 fixed dose combination of pipamperone and citalopram; Drug: Citalopram; Drug: Pipamperone
Sponsors: PharmaNeuroBoost N.V.; PharmaNeuroBoost N.V.
Recruiting - verified March 2012 - Condition: Drug Addiction
Intervention: Drug: Varenicline
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Not yet recruiting - verified December 2011 - Condition: Nicotine Dependence
Interventions: Drug: Varenicline; Drug: Bupropion; Drug: Nicotine patches; Drug: Nicotine Inhaler
Sponsors: Duke University; Duke University; National Institute on Drug Abuse (NIDA); Philip Morris USA, Inc.
Recruiting - verified March 2012 - Condition: Overactive Bladder
Interventions: Drug: Tolterodine ER; Drug: Placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Condition: Smoking Cessation
Interventions: Behavioral: Questionnaires; Drug: Nicotine Patch Therapy; Behavioral: Counseling Sessions
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center; CPRIT - Cancer Prevention Research Institute of Texas
Not yet recruiting - verified November 2011 - Conditions: Overactive Bladder; Bladder, Overactive; Overactive Urinary Bladder
Interventions: Drug: Fesoterodine 8 mg; Drug: Placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified April 2012 - Condition: Smoking Cessation
Interventions: Drug: Nicotine Patches; Behavioral: Telephone Counseling; Behavioral: Brief Hospital Counseling
Sponsors: University of California, San Diego; University of California, San Diego; National Cancer Institute (NCI)
Recruiting - verified January 2011 - Conditions: Smoking; Smoking Cessation
Interventions: Other: Coordinated Care; Other: Usual Care
Sponsors: University of Pittsburgh; University of Pittsburgh; National Institutes of Health (NIH); National Cancer Institute (NCI)
Recruiting - verified September 2011 - Condition: Asthma
Interventions: Drug: Tiotropium; Drug: Salmeterol; Drug: Formoterol
Sponsors: Brigham and Women's Hospital; Brigham and Women's Hospital; Olmsted Medical Center; American Academy of Family Physicians National Research Network; Harvard Clinical Research Institute
Recruiting - verified March 2012 - Condition: Dementia Alzheimer's Type
Interventions: Drug: SAR110894D; Drug: placebo
Sponsors: Sanofi-Aventis; Sanofi-Aventis
Recruiting - verified May 2012 - Condition: Asthma
Interventions: Drug: tiotropium Respimat low dose; Drug: tiotropium Respimat high dose; Drug: placebo Respimat
Sponsors: Boehringer Ingelheim Pharmaceuticals; Boehringer Ingelheim Pharmaceuticals; Pfizer
Recruiting - verified May 2012 - Conditions: Tobacco Use Disorder; Smoking Relapse; Cognitive Training; Nicotine Addiction
Interventions: Behavioral: Cognitive Remediation Training (CRT); Behavioral: Standard Care (SC)
Sponsors: University of Pennsylvania; University of Pennsylvania
Recruiting - verified January 2012 - Condition: Smoking Cessation
Interventions: Drug: Varenicline; Drug: Placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Condition: Pulmonary Disease, Chronic Obstructive
Interventions: Drug: Budesonide+ ipratropium/albuterol; Drug: budesonide/formoterol plus ipratropium/albuterol; Drug: Ipratropium/albuterol
Sponsors: National Jewish Health; National Jewish Health; AstraZeneca
Recruiting - verified April 2012 - Conditions: Smoking Cessation; Overweight; Obesity
Intervention: Drug: Nicotine patch
Sponsors: Yale University; Yale University; American Heart Association
Recruiting - verified February 2012 - Condition: Nicotine
Intervention:
Sponsors: University of Pennsylvania; University of Pennsylvania; National Institute on Drug Abuse (NIDA)
Recruiting - verified December 2011 - Conditions: Depression; Asthma
Interventions: Drug: Escitalopram; Drug: Placebo
Sponsors: University of Texas Southwestern Medical Center; University of Texas Southwestern Medical Center; National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified March 2012 - Condition: Smoking
Intervention: Drug: Donepezil
Sponsors: Abramson Cancer Center of the University of Pennsylvania; Abramson Cancer Center of the University of Pennsylvania
Recruiting - verified May 2012 - Condition: Tobacco Use Disorder
Interventions: Behavioral: Cue Extinction Training; Drug: Nicotine Replacement Therapy; Behavioral: Cue Extinction Therapy; Behavioral: Progressive Muscle Relaxation
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute
Recruiting - verified April 2012 - Condition: Parkinson's Disease
Interventions: Drug: nicotine patch; Drug: placebo
Sponsors: University of Vermont; University of Vermont; Parkinson's Disease Foundation; The Parkinson Study Group
Recruiting - verified October 2010 - Condition: Major Depressive Disorder
Intervention: Drug: Escitalopram
Sponsors: Forest Laboratories; Forest Laboratories
Recruiting - verified February 2012 - Condition: Smoking Addiction
Interventions: Drug: Placebo; Drug: Varenicline
Sponsors: The Mind Research Network; The Mind Research Network; National Institute on Drug Abuse (NIDA)
Recruiting - verified November 2011 - Conditions: Overactive Detrusor; Neurogenic Bladder
Intervention: Drug: Oxybutynin
Sponsors: Watson Pharmaceuticals; Watson Pharmaceuticals
Recruiting - verified February 2012 - Condition: Biomarkers, Pharmacological
Interventions: Drug: Huperzine A; Drug: Donepezil; Drug: Galantamine; Other: Placebo
Sponsors: U.S. Army Medical Research and Materiel Command; U.S. Army Medical Research and Materiel Command; Walter Reed Army Institute of Research (WRAIR)
Recruiting - verified May 2012 - Condition: for Cigarette Smoking and Binge Drinking Cessation
Interventions: Drug: nicotine transdermal patch; Behavioral: behavioral intervention
Sponsors: Mayo Clinic; Mayo Clinic; James and Esther King Biomedical Research Program
Recruiting - verified April 2012 - Conditions: Complicated Grief; Bereavement
Interventions: Drug: Citalopram; Behavioral: Complicated Grief Treatment; Other: Placebo
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute of Mental Health (NIMH); American Foundation for Suicide Prevention
Recruiting - verified March 2012 - Conditions: Alcohol Dependence; Cocaine Dependence
Interventions: Drug: Varenicline; Drug: Placebo
Sponsors: University of Pennsylvania; University of Pennsylvania; National Institute on Drug Abuse (NIDA)
Recruiting - verified August 2011 - Condition: Nicotine Dependence
Interventions: Drug: Varenicline; Behavioral: Individual counseling; Behavioral: Check-ins with medical staff; Behavioral: individual counseling
Sponsors: University of California, San Francisco; University of California, San Francisco; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Condition: Cocaine Dependence
Intervention: Drug: Varenicline
Sponsors: University of Pennsylvania; University of Pennsylvania; National Institute on Drug Abuse (NIDA)
Recruiting - verified August 2011 - Conditions: Drug Addiction; Nicotine Dependence
Intervention: Drug: Nicotrol
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified September 2011 - Condition: Endothelial Dysfunction
Interventions: Drug: Trimethaphan; Drug: Placebo
Sponsors: Vanderbilt University; Vanderbilt University
Recruiting - verified April 2012 - Condition: Tobacco Use Cessation
Interventions: Other: proactive outreach (PRO); Other: Free telephone counseling (TC); Other: Nicotine replacement therapy (NRT); Other: Usual care (UC)
Sponsors: Masonic Cancer Center, University of Minnesota; Masonic Cancer Center, University of Minnesota; National Cancer Institute (NCI)
Recruiting - verified September 2011 - Condition: Fragile X Syndrome
Interventions: Drug: donepezil hydrochloride; Drug: sugar pill
Sponsors: Stanford University; Stanford University; National Institute of Mental Health (NIMH); Autism Speaks
Recruiting - verified July 2011 - Conditions: Smoking; Smoking Cessation; Motivation; Nicotine
Interventions: Drug: Nicotine Patch; Drug: Nicotine Gum; Behavioral: Motivational Interviewing; Behavioral: Smoking Reduction
Sponsors: University of Wisconsin, Madison; University of Wisconsin, Madison; University of Illinois; Dean Health System; Mercy Health System; Aurora Health Care; National Cancer Institute (NCI)
Recruiting - verified August 2011 - Condition: Depression
Intervention: Drug: Scopolamine
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified April 2012 - Conditions: Smoking; Smoking Cessation; Adherence; Nicotine; Motivation
Interventions: Drug: Short Term Combination Nicotine Replacement Therapy (patch + gum); Drug: Long Term Combination Nicotine Replacement Therapy (patch + gum); Behavioral: Intensive Maintenance Counseling; Behavioral: Cognitive Medication Adherence Counseling (C-MAC); Behavioral: Electronic Medication Monitoring Device (the Helping Hand) + Feedback; Behavioral: Automated Adherence Prompting Phone Calls
Sponsors: University of Wisconsin, Madison; University of Wisconsin, Madison; Dean Health System; Mercy Health System; Aurora Health Care; National Cancer Institute (NCI)
Recruiting - verified August 2011 - Conditions: Smoking; Smoking Cessation; Nicotine
Interventions: Behavioral: Counseling before quit attempt; Behavioral: Minimal In-person counseling during quit attempt; Behavioral: Intensive in-person counseling; Behavioral: Minimal phone counseling after quit date; Behavioral: Intensive phone counseling; Drug: Short Term Nicotine Patch During Quit Attempt; Drug: Long Term Nicotine Patch During Quit Attempt; Drug: Short Term Post-Quit Nicotine Gum; Drug: Long Term Nicotine Gum During Quit Attempt; Drug: Pre-Quit Nicotine Gum; Drug: Pre-Quit Nicotine Patch
Sponsors: University of Wisconsin, Madison; University of Wisconsin, Madison; Dean Health System; Mercy Health System; Aurora Health Care; National Cancer Institute (NCI)
Recruiting - verified August 2011 - Conditions: Schizophrenia; Smoking Cessation
Interventions: Other: Sugar Pill; Drug: Varenicline; Drug: Bupropion HCl
Sponsors: University of Minnesota - Clinical and Translational Science Institute; University of Minnesota - Clinical and Translational Science Institute; National Institutes of Health (NIH); National Institute on Drug Abuse (NIDA)
Recruiting - verified August 2011 - Conditions: Head and Neck Cancer; Smoking Cessation
Interventions: Behavioral: Acceptance and Commitment Therapy; Behavioral: Motivational and Behavioral Counseling; Drug: Varenicline
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center
Recruiting - verified April 2012 - Condition: Tobacco Dependence
Intervention: Drug: nicotine patch
Sponsors: University of Massachusetts, Worcester; University of Massachusetts, Worcester
Recruiting - verified April 2012 - Condition: Overactive Bladder
Interventions: Drug: Trospium Chloride (Sanctura XR); Drug: Over-encapsulated Placebo
Sponsors: Allergan; Allergan
Recruiting - verified March 2012 - Condition: Down Syndrome
Interventions: Drug: Rivastigmine; Other: Liquid Placebo
Sponsors: Duke University; Duke University; Taishoff Family Foundation
Recruiting - verified March 2012 - Conditions: Smoking Cessation; Depression
Interventions: Drug: varenicline; Drug: placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Condition: Alzheimer's Disease
Interventions: Drug: Donepezil; Drug: Placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Condition: Smoking
Interventions: Behavioral: Cognitive Behavioral Treatment; Drug: Nicotine Patch; Behavioral: Wellness Program; Behavioral: Aerobic Exercise
Sponsors: Southern Methodist University; Southern Methodist University; National Institute on Drug Abuse (NIDA)
Recruiting - verified July 2011 - Condition: Cigarette Smoking
Intervention: Drug: Deuterated nicotine and cotinine
Sponsors: University of California, San Francisco; University of California, San Francisco
Recruiting - verified March 2012 - Condition: Nicotine Dependence
Interventions: Drug: Bupropion SR; Drug: Nicotine; Drug: Placebo pill and Placebo Patch; Other: Delayed-Quit Control
Sponsors: Southern Illinois University Carbondale; Southern Illinois University Carbondale; National Institute on Drug Abuse (NIDA)
Recruiting - verified September 2011 - Conditions: Nicotine Dependence; Smoking; Sleep Disorders, Intrinsic
Intervention: Behavioral: Exercise
Sponsors: University of Pittsburgh; University of Pittsburgh; National Institute on Drug Abuse (NIDA)
Recruiting - verified May 2012 - Condition: Nicotine Dependence
Intervention: Drug: Transdermal nicotine patch
Sponsors: University of Pennsylvania; University of Pennsylvania; National Institute on Drug Abuse (NIDA)
Recruiting - verified December 2011 - Condition: Schizophrenia
Interventions: Drug: Galantamine; Drug: Galantamine or Placebo
Sponsors: University of Maryland; University of Maryland; National Institute of Mental Health (NIMH)
Recruiting - verified March 2012 - Conditions: Schizophrenia; Schizophreniform Disorder
Interventions: Drug: Citalopram; Behavioral: Psychoeducation; Behavioral: Cognitive Behavioral Therapy (CBT); Radiation: Functional Magnetic Resonance Imaging (fMRI); Drug: Placebo; Behavioral: Psychoeducation; Behavioral: Cognitive Behavioral Therapy (CBT); Radiation: Functional Magnetic Resonance Imaging (fMRI)
Sponsors: National Institute of Mental Health (NIMH); National Institute of Mental Health (NIMH)
Recruiting - verified December 2011 - Conditions: Nicotine Dependence; Schizophrenia
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified August 2011 - Condition: Nicotine Dependence
Intervention: Device: Transcranial Magnetic Stimulation
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA); University of Maryland
Recruiting - verified December 2011 - Condition: Nicotine Dependence
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified January 2011 - Conditions: Cocaine Dependence; Cocaine Addiction; Cocaine Abuse; Substance Abuse
Interventions: Drug: Placebo; Drug: Rivastigmine; Drug: Huperzine A; Drug: Rivastigmine; Drug: Huperzine A
Sponsors: Baylor College of Medicine; Baylor College of Medicine; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Condition: Overactive Bladder in Parkinson's Disease
Interventions: Drug: solifenacin succinate (VESIcare); Drug: placebo
Sponsors: University of South Florida; University of South Florida; Astellas Pharma Inc
Recruiting - verified March 2012 - Conditions: Smoking Cessation; Schizophrenia
Intervention: Drug: Nicotine Nasal Spray
Sponsors: University of Medicine and Dentistry New Jersey; University of Medicine and Dentistry New Jersey; National Institute on Drug Abuse (NIDA)
Recruiting - verified August 2011 - Condition: Alcohol Reactivity
Interventions: Drug: varenicline; Drug: placebo
Sponsors: Yale University; Yale University
Recruiting - verified January 2012 - Condition: Tobacco Use Disorder
Interventions: Drug: Tolcapone; Drug: Placebo
Sponsors: University of Pennsylvania; University of Pennsylvania; National Institute on Drug Abuse (NIDA)
Recruiting - verified January 2012 - Conditions: Smoking Cessation; Smoking
Interventions: Behavioral: Standard Treatment (ST); Behavioral: Telephone Counseling; Behavioral: Quitline; Behavioral: Nicotine Replacement Therapy (NRT)
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center; National Cancer Institute (NCI)
Recruiting - verified December 2011 - Condition: Influence of OPRM1 A118G Status on Subjective Responses to IV Nicotine.
Intervention: Drug: Nicotine
Sponsors: Yale University; Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified December 2011 - Condition: Back Pain
Interventions: Behavioral: cognitive behavioral therapy; Drug: desipramine hydrochloride; Behavioral: cognitive behavioral therapy; Drug: benztropine mesylate 0.125 mg daily; Drug: desipramine hydrochloride
Sponsors: Department of Veterans Affairs; Department of Veterans Affairs; University of California, San Diego
Recruiting - verified April 2012 - Condition: Major Depressive Disorder
Intervention: Drug: escitalopram and adjunctive aripiprazole and placebo
Sponsors: Washington University School of Medicine; Washington University School of Medicine
Recruiting - verified August 2011 - Condition: Amblyopia
Interventions: Drug: Atropine; Device: Plano lens; Drug: Atropine
Sponsors: Jaeb Center for Health Research; Jaeb Center for Health Research; National Eye Institute (NEI)
Recruiting - verified January 2012 - Condition: Smoking Cessation
Interventions: Drug: Varenicline; Drug: Bupropion; Other: Placebo; Behavioral: Counseling/Phone Calls
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center; National Institutes of Health (NIH); National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2012 - Condition: Smokeless Tobacco Use
Interventions: Drug: nicotine replacement therapy (nicotine patches); Drug: placebo NRT
Sponsors: Mayo Clinic; Mayo Clinic
Recruiting - verified January 2012 - Conditions: Cigarette Smoking; Nicotine Dependence; Post-traumatic Stress Disorder; Tobacco Use Disorder
Interventions: Drug: Varenicline; Behavioral: Medication Management Counseling; Behavioral: Prolonged Exposure
Sponsors: University of Pennsylvania; University of Pennsylvania; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Conditions: Nicotine Dependence; Smoking Cessation
Interventions: Other: Varenicline and smoking cessation counseling; Behavioral: Exercise or relaxation treatment
Sponsors: University of Connecticut Health Center; University of Connecticut Health Center; National Institutes of Health (NIH); National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2012 - Condition: Lower Urinary Tract Symptoms
Interventions: Drug: dutasteride 0.5 mg, used with tolterodine ER 4mg or placebo; Drug: dutasteride
Sponsors: Siami, Paul F., M.D.; Siami, Paul F., M.D.; GlaxoSmithKline; Pfizer
Recruiting - verified July 2011 - Conditions: Alzheimer's Disease; Agitation
Interventions: Drug: citalopram; Drug: placebo
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute on Aging (NIA); National Institute of Mental Health (NIMH)
Recruiting - verified May 2012 - Condition: Coronary Artery Disease
Intervention:
Sponsors: Henry Ford Health System; Henry Ford Health System
Recruiting - verified May 2010 - Condition: Short Bowel Syndrome
Intervention: Drug: Citalopram
Sponsors: University of Nebraska; University of Nebraska
Recruiting - verified August 2011 - Conditions: Cigarette Smoking; Hypertension
Interventions: Drug: Varenicline; Behavioral: behavioral therapy
Sponsors: University of Connecticut Health Center; University of Connecticut Health Center; National Institute on Drug Abuse (NIDA)
Recruiting - verified December 2011 - Condition: Ischemic Stroke
Interventions: Drug: donepezil; Drug: placebo
Sponsors: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - verified February 2012 - Condition: Major Depressive Disorder
Intervention: Drug: Creatine Monohydrate
Sponsors: University of Utah; University of Utah; AlzChem, LLC
Recruiting - verified April 2012 - Condition: Postpartum Depression
Intervention: Drug: Escitalopram
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; Forest Laboratories
Recruiting - verified July 2011 - Condition: Cocaine Dependence
Interventions: Drug: Galantamine; Drug: placebo
Sponsors: Yale University; Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2012 - Condition: Substance Abuse
Interventions: Drug: Nicotine Replacement Treatment (NRT); Behavioral: Brief Advice
Sponsors: Brown University; Brown University; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2009 - Conditions: Schizophrenia; Cigarette Smoking
Interventions: Drug: Varenicline; Drug: Placebo for varenicline
Sponsors: Nathan Kline Institute for Psychiatric Research; Nathan Kline Institute for Psychiatric Research
Recruiting - verified May 2012 - Conditions: Mood Disorder; Mental Disorder Diagnosed in Childhood; Attention Deficit and Disruptive Behavior Disorder; Attention Deficit Hyperactivity Disorder
Interventions: Drug: Citalopram; Drug: Methylphenidate
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Mental Health (NIMH)
Recruiting - verified July 2011 - Condition: Postoperative Pain
Intervention: Drug: transdermal nicotine patch
Sponsors: Stony Brook University; Stony Brook University
Recruiting - verified August 2011 - Conditions: Bladder Cancer; Cervical Cancer; Esophageal Cancer; Gastric Cancer; Head and Neck Cancer; Kidney Cancer; Leukemia; Liver Cancer; Lung Cancer; Pancreatic Cancer; Tobacco Use Disorder
Interventions: Drug: nicotine; Drug: varenicline; Other: placebo
Sponsors: Butler Hospital; Butler Hospital; National Cancer Institute (NCI)
Recruiting - verified March 2012 - Condition: Smoking
Interventions: Drug: naltrexone; Drug: varenicline; Drug: placebo
Sponsors: Yale University; Yale University
Recruiting - verified January 2012 - Conditions: Smoking Cessation; Nicotine Dependence
Interventions: Drug: Nicotine Replacement Treatment (NRT); Drug: varenicline; Behavioral: Behavioral counseling for smoking cessation; Drug: Placebo patch; Drug: Placebo
Sponsors: Brown University; Brown University; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2009 - Condition: Spinal Cord Injury
Intervention: Drug: Neostigmine
Sponsors: Department of Veterans Affairs; Department of Veterans Affairs
Recruiting - verified May 2012 - Condition: Bipolar Disorder
Interventions: Drug: Galantamine-ER; Drug: Galantamine placebo
Sponsors: National Institute of Mental Health (NIMH); National Institute of Mental Health (NIMH); Massachusetts General Hospital; Mount Sinai School of Medicine
Recruiting - verified January 2012 - Conditions: Attention Deficit Hyperactivity Disorder; Nicotine Dependence
Interventions: Drug: Lis-dexamphetamine (LDX; Vyvanse) and Transdermal Nicotine Patch; Drug: Placebo and transdermal nicotine patch
Sponsors: Duke University; Duke University; Shire Development LLC
Recruiting - verified June 2011 - Condition: Neurogenic Detrusor Overactivity
Interventions: Drug: Darifenacin; Drug: Darifenacin; Drug: Darifenacin; Drug: Darifenacin
Sponsors: Warner Chilcott; Warner Chilcott
Recruiting - verified May 2012 - Condition: Asthma
Intervention: Drug: salmeterol
Sponsors: Nemours Children's Clinic; Nemours Children's Clinic; University of Florida
Recruiting - verified August 2011 - Conditions: Smoking; HIV Infections
Interventions: Drug: Varenicline tartrate; Drug: Nicotine Replacement Therapy; Other: Biological Control; Behavioral: Motivational Interview
Sponsors: Ohio State University; Ohio State University; National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified August 2011 - Condition: Depression
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Mental Health (NIMH)
Recruiting - verified December 2011 - Condition: Alcohol Drinking
Interventions: Drug: Varenicline; Drug: Varenicline (Chantix)
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified November 2011 - Condition: Major Depressive Disorder
Interventions: Drug: Escitalopram; Drug: Sertraline; Drug: Venlafaxine XR
Sponsors: BRC Operations Pty. Ltd.; BRC Operations Pty. Ltd.
Recruiting - verified March 2012 - Conditions: Breast Cancer; Depression; Hot Flashes; Psychosocial Effects of Cancer and Its Treatment
Interventions: Drug: citalopram hydrobromide; Drug: escitalopram oxalate; Drug: gabapentin; Drug: sertraline hydrochloride; Drug: tamoxifen citrate; Drug: venlafaxine; Genetic: molecular genetic technique; Other: high performance liquid chromatography; Other: laboratory biomarker analysis; Other: pharmacological study; Procedure: adjuvant therapy
Sponsors: Mayo Clinic; Mayo Clinic; National Cancer Institute (NCI)
Recruiting - verified April 2012 - Condition: Nicotine Dependence
Interventions: Drug: varenicline; Device: transdermal nicotine patch
Sponsors: Medical University of South Carolina; Medical University of South Carolina
Recruiting - verified July 2010 - Condition: Smoking
Intervention: Other: Functional Magnetic Resonance Imaging (fMRI)
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center; National Institutes of Health (NIH)
Recruiting - verified December 2011 - Conditions: Smoking; Smoking Cessation
Interventions: Drug: Nicotine Patch; Behavioral: Tobacco Quit Line Program
Sponsors: University of Tennessee; University of Tennessee; National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified October 2011 - Conditions: Stress Disorders, Posttraumatic; Tobacco Use Disorder
Interventions: Drug: Nicotine; Behavioral: Cognitive Behavioral Therapy for Smoking Cessation; Drug: Bupropion SR
Sponsors: Department of Veterans Affairs; Department of Veterans Affairs
Recruiting - verified March 2012 - Condition: Substance-related Discorder
Interventions: Drug: Nicotine; Drug: Carfentanil
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA); Johns Hopkins University
Recruiting - verified June 2011 - Conditions: Diabetic Neuropathic Pain; Chronic Low Back Pain
Interventions: Drug: donepezil; Drug: duloxetine; Drug: donepezil 2.5 mg and duloxetine 30mg; Drug: placebo; Drug: gabapentin
Sponsors: Wake Forest University; Wake Forest University; National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified February 2012 - Condition: Depression
Intervention: Drug: citalopram and escitalopram
Sponsors: Mayo Clinic; Mayo Clinic; National Institutes of Health (NIH)
Recruiting - verified May 2012 - Condition: Smoking Lapse Behavior
Interventions: Drug: varenicline; Drug: bupropion; Drug: Placebo
Sponsors: Yale University; Yale University
Recruiting - verified January 2012 - Condition: Alcohol Drinking
Interventions: Drug: varenicline; Drug: bupropion; Drug: placebo
Sponsors: Yale University; Yale University
Recruiting - verified January 2012 - Condition: Obesity
Interventions: Drug: Trimethaphan L-NMMA Insulin clamp; Drug: Saline, Insulin clamp
Sponsors: Vanderbilt University; Vanderbilt University
Recruiting - verified May 2012 - Conditions: Chronic Fatigue Syndrome; Orthostatic Intolerance; Postural Tachycardia Syndrome
Interventions: Other: Autonomic Function Testing; Other: Saline infusions; Drug: L-NMMA trimethaphan; Drug: methyldopa
Sponsors: Vanderbilt University; Vanderbilt University
Recruiting - verified May 2012 - Conditions: Bipolar Disorder; Bipolar Depression
Interventions: Drug: citalopram + mood stabilizer; Procedure: FDG PET scans; Procedure: MRI structural scans; Procedure: Genotyping; Procedure: Blood Draw; Drug: placebo + mood stabilizer
Sponsors: Tufts Medical Center; Tufts Medical Center; National Institute of Mental Health (NIMH)
Recruiting - verified July 2011 - Conditions: Smoking Cessation; Tobacco Use Disorder
Interventions: Drug: Nicotine patches; Behavioral: Telephone counseling; Behavioral: iQuit Smoking website
Sponsors: University of Michigan; University of Michigan; National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified January 2012 - Conditions: Smoking; Depression
Interventions: Behavioral: Smoking Cessation Treatment; Behavioral: Nicotine Replacement Therapy; Behavioral: CBASP
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center; National Institute of Mental Health (NIMH)
Recruiting - verified May 2012 - Condition: Depression
Interventions: Drug: Escitalopram; Drug: Desipramine
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute of Mental Health (NIMH)
Recruiting - verified April 2012 - Conditions: Unipolar Depression; Bipolar Depression
Intervention: Drug: Scopolamine
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Mental Health (NIMH)
Recruiting - verified February 2012 - Condition: Depression
Interventions: Drug: Escitalopram; Drug: Duloxetine; Behavioral: Cognitive behavioral therapy (CBT)
Sponsors: National Institute of Mental Health (NIMH); National Institute of Mental Health (NIMH); Emory University
Recruiting - verified December 2011 - Condition: Alcoholism
Intervention: Drug: mecamylamine
Sponsors: Yale University; Elizabeth Ralevski
Recruiting - verified January 2012 - Conditions: Smoking; Tobacco Use Cessation
Interventions: Behavioral: MBAT Group Therapy; Drug: Nicotine; Behavioral: Group Therapy; Behavioral: Individual Therapy
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center; National Institute on Drug Abuse (NIDA)
Recruiting - verified May 2012 - Conditions: Tachycardia; Chronic Orthostatic Intolerance
Interventions: Drug: Acetazolamide; Drug: Atomoxetine; Other: Baseline (No Drug); Drug: Clonidine; Drug: Entacapone; Drug: Entacapone & Propranolol; Drug: Atomoxetine & Propranolol; Drug: Indomethacin; Drug: Mecamylamine; Drug: Isosorbide Dinitrate; Dietary Supplement: Melatonin; Drug: Midodrine; Drug: Modafinil; Drug: Octreotide; Radiation: Placebo; Drug: Propranolol; Drug: Modafinil & Propranolol; Drug: Sertraline; Procedure: IV Saline; Other: Drinking Water; Device: Breathing Device; Drug: memantine; Device: Abdominal binder
Sponsors: Vanderbilt University; Satish R. Raj; National Institutes of Health (NIH)
Recruiting - verified February 2012 - Condition: Functional Dyspepsia
Interventions: Drug: Amitriptyline; Drug: escitalopram; Drug: placebo
Sponsors: Mayo Clinic; Mayo Clinic; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified January 2012 - Condition: Hyperlipidemia
Interventions: Drug: Tetraethylammonium (TEA); Drug: L-NMMA; Drug: Bradykinin; Drug: Nitroprusside; Drug: S-methyl-L-thiocitrulline (SMTC); Drug: Acetylcholine
Sponsors: Emory University; Emory University
Recruiting - verified May 2012 - Conditions: OBESITY; HYPERTENSION; PURE AUTONOMIC FAILURE; SHY-DRAGER SYNDROME
Interventions: Drug: Trimethaphan; Drug: Trimethaphan; Drug: Pseudoephedrine
Sponsors: Vanderbilt University; Vanderbilt University
Recruiting - verified May 2012 - Conditions: Autonomic Failure; Orthostatic Hypotension
Interventions: Drug: Atomoxetine; Drug: Acarbose; Drug: Pyridostigmine Bromide; Drug: Yohimbine; Drug: Midodrine HCl; Drug: placebo; Drug: Modafinil; Drug: Octreotide; Other: water intake; Drug: Diphenhydramine Hydrochloride; Drug: Ranitidine HCL; Drug: Tranylcypromine; Drug: Ergotamine/ Caffeine; Drug: Celecoxib; Drug: Pseudoephedrine; Drug: Methylphenidate; Drug: Indomethacin; Drug: Ibuprofen; Drug: Oxymetazoline 0.05% nasal solution; Dietary Supplement: Bovril; Drug: Acetazolamide; Drug: Rivastigmine tartrate; Drug: Carbidopa/levodopa; Device: abdominal binder; Device: abdominal binder (sham)
Sponsors: Vanderbilt University; Vanderbilt University
Recruiting - verified May 2012 - Conditions: Anxiety Disorders; Somatoform Disorders
Interventions: Drug: Escitalopram; Drug: Placebo; Drug: Escitalopram extension
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; National Institute of Mental Health (NIMH); Rhode Island Hospital
Recruiting - verified May 2012 - Conditions: Mood Disorders; Healthy; Unipolar Depression; Bipolar Depression
Intervention: Drug: Transderm Scopolamine
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Mental Health (NIMH)
Recruiting - verified July 2011
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Cholinergic Clinical Trials |
