- Conditions: Obesity; Overweight
Interventions: Drug: NB32; Drug: PBO; Behavioral: Weight Management Program
Sponsors: Orexigen Therapeutics, Inc; Orexigen Therapeutics, Inc
Not yet recruiting - verified May 2012 - Condition: Prescription Opiate/Medication Dependence
Intervention: Drug: Vivitrol
Sponsors: University of Pennsylvania; University of Pennsylvania
Recruiting - verified April 2012 - Condition: Chronic Pain
Interventions: Drug: ALO-02; Drug: Placebo
Sponsors: Pfizer; Pfizer
Not yet recruiting - verified May 2012 - Condition: Substance-Related Disorders
Intervention: Drug: naltrexone for extended release injectable suspension
Sponsors: Rhode Island Hospital; Rhode Island Hospital; National Institute on Drug Abuse (NIDA); Alkermes
Recruiting - verified March 2012 - Condition: Management of Moderate to Severe Pain
Interventions: Drug: ALO-02; Drug: Naltrexone block; Drug: ALO-02; Drug: Naltrexone block; Drug: OxyContin; Drug: Naltrexone block
Sponsors: Pfizer; Pfizer
Recruiting - verified April 2012 - Condition: Opiate Dependence
Interventions: Drug: Vivitrol; Behavioral: Employment based opiate abstinence reinforcement; Other: Usual Care Control
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute on Drug Abuse (NIDA)
Not yet recruiting - verified March 2012 - Condition: Management of Moderate to Severe Pain
Interventions: Drug: Oxycodone; Drug: Oxycodone; Drug: Oxycodone; Drug: Oxycodone; Drug: Oxycodone
Sponsors: Pfizer; Pfizer
Recruiting - verified April 2012 - Condition: Management of Moderate to Severe Pain
Interventions: Drug: Oxycodone; Drug: Oxycodone; Drug: Oxycodone; Drug: Oxycodone; Drug: Oxycodone
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Condition: Alcohol Drinking
Interventions: Drug: Naltrexone and memantine; Drug: Naltrexone and Placebo
Sponsors: Yale University; Yale University; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified January 2012 - Conditions: Opioid-Related Disorders; Heroin Dependence
Intervention: Drug: Naltrexone
Sponsors: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA); Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA); ZonMw: The Netherlands Organisation for Health Research and Development; Alkermes
Not yet recruiting - verified November 2011 - Condition: Pathological Gambling
Interventions: Drug: Naltrexone pharmacotherapy; Drug: Placebo
Sponsors: National Institute for Health and Welfare, Finland; National Institute for Health and Welfare, Finland
Recruiting - verified February 2012 - Condition: Hypoglycemia
Intervention: Drug: Naltrexone
Sponsors: Yale University; Yale University; National Institutes of Health (NIH)
Recruiting - verified October 2011 - Condition: Opioid Dependence
Intervention: Drug: VIVITROL 380mg
Sponsors: Alkermes; Alkermes
Recruiting - verified November 2011 - Condition: Amphetamine-Related Disorders
Interventions: Drug: extended-release naltrexone; Drug: Placebo
Sponsors: National Institute on Drug Abuse (NIDA); National Institute on Drug Abuse (NIDA); Alkermes
Not yet recruiting - verified October 2011 - Condition: Opioid Dependence
Intervention:
Sponsors: Alkermes; Alkermes
Recruiting - verified April 2012 - Condition: Cocaine Dependence
Interventions: Drug: Buprenorphine + Naltrexone; Drug: Placebo + Naltrexone
Sponsors: University of California, Los Angeles; Walter Ling; National Institute on Drug Abuse (NIDA); The EMMES Corporation
Recruiting - verified February 2012 - Condition: Opiate Dependence
Interventions: Drug: Vivitrol; Drug: Naltrexone (oral); Behavioral: BDRC; Behavioral: Medical Management
Sponsors: Yale University; Yale University; St. Petersburg State Pavlov Medical University; National Institute on Drug Abuse (NIDA)
Not yet recruiting - verified July 2011 - Condition: Opioid Dependence
Interventions: Drug: Opioid detoxification using buprenorphine vs. oral naltrexone; Drug: Buprenorphine
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute
Recruiting - verified June 2011 - Conditions: HIV; Alcohol Use Disorder
Interventions: Drug: Extended release-naltrexone; Drug: Placebo injection
Sponsors: Fred Hutchinson Cancer Research Center; Fred Hutchinson Cancer Research Center; Yale University; Asociación Civil Impacta Salud y Educación, Peru
Not yet recruiting - verified June 2011 - Condition: Methamphetamine Dependence
Interventions: Other: placebo; Drug: Naltrexone and Bupropion SR
Sponsors: National Institute on Drug Abuse (NIDA); National Institute on Drug Abuse (NIDA)
Recruiting - verified August 2011 - Condition: Alcohol Abuse
Interventions: Device: AGATE; Device: SASED
Sponsors: Talaria, Inc; Talaria, Inc; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified September 2011 - Condition: Alcohol Dependence
Interventions: Drug: Valproate; Drug: Naltrexone
Sponsors: Department of Veterans Affairs; Department of Veterans Affairs
Recruiting - verified March 2012 - Conditions: Temporomandibular Disorder; Facial Pain
Interventions: Drug: Naltrexone; Drug: Placebo
Sponsors: University of Florida; University of Florida; American Pain Society
Recruiting - verified March 2011 - Condition: Malignant Glioma
Interventions: Drug: Naltrexone; Other: Placebo
Sponsors: Duke University; Duke University; Brain Tumor Fund for the Carolinas
Recruiting - verified March 2012 - Conditions: Alcohol Dependence; Alcohol Abuse
Interventions: Drug: Naltrexone; Behavioral: Brenda Therapy Sessions
Sponsors: University of North Carolina, Chapel Hill; University of North Carolina, Chapel Hill; National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Institutes of Health (NIH)
Recruiting - verified January 2012 - Conditions: HIV; AIDS; Opioid Dependence; Drug Dependence
Intervention: Drug: Depot Naltrexone
Sponsors: Yale University; Yale University; Baystate Medical Center
Recruiting - verified August 2011 - Conditions: HIV; Alcoholism
Intervention: Drug: Naltrexone
Sponsors: University of Florida; University of Florida; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified April 2012 - Condition: Reduction in Heavy Drinking in Patients With HIV
Interventions: Drug: Naltrexone; Other: Placebo + Medication Management/Medication Coaching
Sponsors: Yale University; Yale University; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified January 2012 - Condition: Alcoholism
Interventions: Drug: N-acetylcysteine + high-dose naltrexone (150 mg); Drug: High-dose naltrexone (150 mg) alone; Drug: Low-dose naltrexone (50 mg) alone
Sponsors: Department of Veterans Affairs; Department of Veterans Affairs
Recruiting - verified March 2012 - Condition: Alcohol-dependence
Intervention: Drug: Naltrexone
Sponsors: Tel-Aviv Sourasky Medical Center; Tel-Aviv Sourasky Medical Center; Ministry of Health, Israel
Not yet recruiting - verified March 2012 - Conditions: HIV; Substance Abuse; HIV Infections
Interventions: Drug: Oral Naltrexone (ON); Drug: Implantable Naltrexone (IN)
Sponsors: University of Pennsylvania; University of Pennsylvania; National Institute on Drug Abuse (NIDA)
Not yet recruiting - verified January 2012 - Conditions: Alcohol Dependence; Problem Drinking; Hazardous Drinking; Human Immunodeficiency Virus; AIDS
Interventions: Drug: Vivitrol- Intramuscular naltrexone (depot-formulation); Drug: Placebo
Sponsors: Yale University; Yale University; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified August 2011 - Condition: Pathological Gambling
Interventions: Drug: Naltrexone; Other: Placebo
Sponsors: Yale University; Yale University; National Center for Responsible Gaming
Recruiting - verified February 2012 - Conditions: Type 1 Diabetes; Hypoglycemia Unawareness
Interventions: Drug: Naltrexone; Drug: Naltrexone
Sponsors: University of Minnesota - Clinical and Translational Science Institute; University of Minnesota - Clinical and Translational Science Institute; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); American Diabetes Association
Recruiting - verified August 2011 - Condition: Impulse Control Disorders in Parkinson's Disease
Intervention: Drug: Naltrexone
Sponsors: University of Pennsylvania; University of Pennsylvania; Michael J. Fox Foundation for Parkinson's Research
Recruiting - verified November 2011 - Condition: Opioid Dependence
Interventions: Drug: injectable naltrexone plus dronabinol; Drug: Naltrexone plus placebo
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute on Drug Abuse (NIDA)
Recruiting - verified May 2012 - Conditions: Neoplasms; Constipation; Opioid-Related Disorders
Intervention: Drug: Methylnaltrexone bromide
Sponsors: University of Vermont; University of Vermont
Recruiting - verified March 2012 - Condition: Opiate Addiction
Interventions: Drug: Buprenorphine/naloxone; Drug: Naltrexone
Sponsors: State University of New York at Buffalo; State University of New York at Buffalo
Recruiting - verified February 2011 - Conditions: Hazardous Drinking; Cigarette Smoking
Interventions: Drug: Naltrexone; Drug: Placebo
Sponsors: Brown University; Brown University
Recruiting - verified October 2011 - Condition: Alcohol Dependence
Interventions: Drug: Drug; Drug: Placebo
Sponsors: Medical University of South Carolina; Medical University of South Carolina; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified April 2012 - Condition: Alcohol Dependence
Interventions: Drug: naltrexone; Drug: Placebo
Sponsors: University of Pennsylvania; University of Pennsylvania; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified August 2011 - Condition: Trichotillomania
Interventions: Drug: Naltrexone; Drug: Placebo
Sponsors: University of Minnesota - Clinical and Translational Science Institute; University of Minnesota - Clinical and Translational Science Institute
Recruiting - verified March 2012 - Condition: Smoking
Interventions: Drug: naltrexone; Drug: varenicline; Drug: placebo
Sponsors: Yale University; Yale University
Recruiting - verified January 2012 - Condition: Opioid-Induced Constipation
Intervention: Drug: Methylnaltrexone bromide
Sponsors: Salix Pharmaceuticals; Salix Pharmaceuticals; Progenics Pharmaceuticals, Inc.
Recruiting - verified January 2012 - Condition: Opioid-Induced Constipation
Interventions: Drug: Methylnaltrexone bromide; Drug: Placebo
Sponsors: Salix Pharmaceuticals; Salix Pharmaceuticals; Progenics Pharmaceuticals, Inc.
Recruiting - verified January 2012 - Condition: Opiate Dependence
Interventions: Behavioral: Behavioral: Buprenorphine/naloxone maintenance (Mtn); Behavioral: Behavioral: Buprenorphine/naloxone detoxification (Dtx)
Sponsors: Yale University; Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified November 2011 - Condition: Breast Cancer
Interventions: Drug: naltrexone hydrochloride; Procedure: Positron-emission tomography (PET) / computed tomography (CT)
Sponsors: Masonic Cancer Center, University of Minnesota; Masonic Cancer Center, University of Minnesota
Recruiting - verified March 2012
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