- Condition: MELAS Syndrome
Intervention: Drug: L-Arginine
Sponsors: The Hospital for Sick Children; The Hospital for Sick Children
Not yet recruiting - verified May 2012 - Condition: Metabolic Bone Disease
Intervention:
Sponsors: The Hospital for Sick Children; The Hospital for Sick Children; Rare Disease Foundation
Not yet recruiting - verified May 2012 - Conditions: Healthy Infants; Immunization; Pain Management
Intervention: Behavioral: Tactile stimulation
Sponsors: University of Toronto; University of Toronto
Not yet recruiting - verified May 2012 - Condition: Hyperlipidemia
Intervention: Drug: Sitagliptin
Sponsors: University Health Network, Toronto; University Health Network, Toronto; Merck Frosst Canada Ltd.
Not yet recruiting - verified April 2012 - Conditions: To Determine the Effects of an ad Libitum Intake of 1%; Milk, Fruit Juice, Regular Soda, Diet Soda and Water, as Part of a Pizza Meal, on Meal Food Intake, Appetite and Postprandial Blood Glucose in Healthy Men and; Women.
Intervention: Other: Nutritional Intervention
Sponsors: University of Toronto; University of Toronto
Active, not recruiting - verified June 2011 - Condition: Obesity
Interventions: Procedure: clinic-based nasopharyngoendoscopy; Procedure: Standard Endoscopy
Sponsors: McMaster University; Dennis Hong MD; Vantage Endoscopy
Not yet recruiting - verified May 2012 - Condition: Psychomotor Impairment
Interventions: Drug: delta-9-tetrahydrocannabinol; Drug: Placebo
Sponsors: Centre for Addiction and Mental Health; Centre for Addiction and Mental Health; Canadian Institutes of Health Research (CIHR); Health Canada
Not yet recruiting - verified May 2012 - Condition: Reflex Sympathetic Dystrophy
Intervention:
Sponsors: Lawson Health Research Institute; Lawson Health Research Institute
Recruiting - verified April 2012 - Conditions: Dyslipidemia; Diabetes; Prediabetes; Dysglycemia; Overweight; Obesity; Hypertension; Metabolic Syndrome; Cardiovascular Disease
Intervention: Other: Dietary pulses
Sponsors: University of Toronto; University of Toronto; Canadian Institutes of Health Research (CIHR); Canada Research Chair Endowment of the Federal Government of Canada; Canadian Institutes of Health Research (CIHR) Postdoctoral Fellowship Award; Pulse Canada
Active, not recruiting - verified April 2012 - Condition: Pharmacodyamics and Pharmacokinetics of Tasimelteon Alone and in Combination With Ethanol
Interventions: Drug: tasimelteon; Drug: Ethanol; Other: Placebo tasimelteon; Drug: Placebo ethanol
Sponsors: Vanda Pharmaceuticals; Vanda Pharmaceuticals
Recruiting - verified April 2012 - Conditions: Cardiovascular Diseases; Diabetes; Abdominal Obesity
Interventions: Behavioral: Multimedia Lifestyle Improvement; Behavioral: Usual Care
Sponsors: McMaster University; McMaster University
Active, not recruiting - verified April 2012 - Conditions: Type 2 Diabetes Mellitus; Gestational Diabetes
Interventions: Device: Continuous Glucose Monitoring; Device: Glucose Meter
Sponsors: Lawson Health Research Institute; Dr. Stewart Harris; Juvenile Diabetes Research Foundation
Not yet recruiting - verified April 2012 - Condition: Healthy
Intervention: Dietary Supplement: protein intake. On the study day, the diet will be provided as free amino acids, with calories made up by a liquid diet and protein free cookies.
Sponsors: The Hospital for Sick Children; The Hospital for Sick Children; Canadian Institutes of Health Research (CIHR)
Recruiting - verified April 2012 - Condition: Cognitive Impairment
Interventions: Other: Dual task gait training; Other: Dual task gait training; Other: Aerobic exercise class
Sponsors: Parkwood Hospital, London, Ontario; Parkwood Hospital, London, Ontario; University of Western Ontario, Canada; Canadian Institutes of Health Research (CIHR)
Not yet recruiting - verified April 2012 - Condition: Drug Abuse
Intervention: Drug: 45-mg hydrocodone bitartrate extended-release tablet (crushed or intact)
Sponsors: Teva Pharmaceutical Industries; Cephalon
Completed - verified May 2012 - Condition: Obesity
Interventions: Behavioral: Home-Based Health Coaching; Behavioral: Mailed materials
Sponsors: Harvard Pilgrim Health Care; Harvard Pilgrim Health Care; Centers for Disease Control and Prevention; Harvard School of Public Health
Active, not recruiting - verified March 2012 - Condition: Pulmonary Arterial Hypertension
Intervention: Radiation: 18 F- Fluoro-6-thiaheptadecanoic Acid ( FTHA)
Sponsors: University of Ottawa Heart Institute; University of Ottawa Heart Institute; Heart and Stroke Foundation of Ontario
Recruiting - verified April 2012 - Condition: Lower Urinary Tract Symptoms
Interventions: Behavioral: Group urotherapy; Behavioral: Individual Urotherapy
Sponsors: Hamilton Health Sciences Corporation; Hamilton Health Sciences Corporation
Not yet recruiting - verified April 2012 - Condition: Total Parenteral Nutrition-induced Cholestasis
Interventions: Drug: Soybean oil based emulsion; Drug: Soybean oil based emulsion+Fish oil based emulsion
Sponsors: University Health Network, Toronto; University Health Network, Toronto; ASPEN Rhoads Research Foundation; Fresenius Kabi; University of Alberta; Foothills Medical Centre; St. Boniface General Hospital Research Centre; Hamilton Health Sciences Corporation; St. Paul's Hospital, Canada
Recruiting - verified February 2012 - Condition: Healthy
Interventions: Dietary Supplement: Fish Oil; Dietary Supplement: PCSO-524
Sponsors: Nutrasource Diagnostics Inc.; Nutrasource Diagnostics Inc.; Pharmalink International Ltd.
Not yet recruiting - verified March 2012 - Conditions: Respiratory Aspiration; Pregnancy
Interventions: Other: Empty; Other: Fluid; Other: Solid
Sponsors: Samuel Lunenfeld Research Institute, Mount Sinai Hospital; Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Recruiting - verified March 2012 - Condition: Pain
Intervention: Drug: Remifentanil
Sponsors: Samuel Lunenfeld Research Institute, Mount Sinai Hospital; Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Recruiting - verified March 2012 - Condition: Pain
Interventions: Drug: bupivacaine, fentanyl; Drug: fentanyl
Sponsors: Samuel Lunenfeld Research Institute, Mount Sinai Hospital; Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Recruiting - verified March 2012 - Condition: Overweight
Interventions: Other: Increased Dairy Intake; Other: Supplemental carbohydrate
Sponsors: Brock University; Brock University
Not yet recruiting - verified March 2012 - Condition: The Focus is to Assess 25-hydroxyvitamin D Levels and Well-being
Interventions: Dietary Supplement: High dose; Dietary Supplement: Reference dose
Sponsors: University of Toronto; University of Toronto
Active, not recruiting - verified March 2012 - Condition: Surgical Education
Intervention: Other: STAC curriculum
Sponsors: St. Michael's Hospital, Toronto; St. Michael's Hospital, Toronto
Completed - verified March 2012 - Condition: Coronary Artery Disease
Intervention: Drug: 123I-CMICE-013
Sponsors: University of Ottawa Heart Institute; University of Ottawa Heart Institute; Canadian Institutes of Health Research (CIHR)
Recruiting - verified April 2012 - Condition: Endotracheal Intubation
Intervention: Device: ETT First (GlideScope)
Sponsors: Lawson Health Research Institute; Lawson Health Research Institute
Not yet recruiting - verified March 2012 - Conditions: Hypercholesterolemia; Cardiovascular Disease; CRP
Intervention: Other: Standardized soy containing muffin
Sponsors: Guelph Food Research Centre; Guelph Food Research Centre; University of Guelph; Glycemic Index Laboratories, Inc; Canadian Centre for Agri-food Research in Health and Medicine
Not yet recruiting - verified March 2012 - Conditions: Hepatitis C; Hypertension
Interventions: Drug: Amlodipine; Drug: Diltiazem
Sponsors: Ottawa Hospital Research Institute; Ottawa Hospital Research Institute; Merck
Not yet recruiting - verified March 2012 - Condition: Arteriosclerosis of Arterial Coronary Artery Bypass Graft
Intervention:
Sponsors: Lawson Health Research Institute; Lawson Health Research Institute
Enrolling by invitation - verified March 2012 - Condition: Ulcerative Colitis
Interventions: Other: Fecal transplant; Other: Placebo enema
Sponsors: Hamilton Health Sciences Corporation; Hamilton Health Sciences Corporation
Not yet recruiting - verified March 2012 - Conditions: High Oxidation Stress; Oxidized LDL Level
Interventions: Dietary Supplement: ORAC-15M™ Grape Extract; Other: Placebo
Sponsors: Ethical Naturals, Inc.; Ethical Naturals, Inc.; KGK Synergize Inc.
Recruiting - verified March 2012 - Condition: Healthy Children
Intervention: Other: nutrition
Sponsors: McMaster University; McMaster University; Nestec Ltd.
Recruiting - verified May 2012 - Condition: Hypertension
Intervention:
Sponsors: North Toronto Primary Care Research Network; North Toronto Primary Care Research Network
Not yet recruiting - verified April 2012 - Conditions: Parenting; Breastfeeding
Intervention: Behavioral: Coparenting Breastfeeding Support Intervention
Sponsors: University of Toronto; University of Toronto
Not yet recruiting - verified January 2012 - Condition: Hypertension
Interventions: Behavioral: e-Counseling plus Usual Care; Behavioral: Control
Sponsors: University Health Network, Toronto; University Health Network, Toronto
Not yet recruiting - verified January 2012 - Conditions: Major Depression; Bipolar Disorder
Intervention:
Sponsors: McMaster University; McMaster University; Ontario Mental Health Foundation; Canadian Institutes of Health Research (CIHR); AstraZeneca
Recruiting - verified June 2005 - Condition: Normal Left Ventricular Function
Intervention:
Sponsors: University of Ottawa Heart Institute; University of Ottawa Heart Institute
Recruiting - verified January 2012 - Conditions: Schizophrenia; Nicotine Addiction
Interventions: Device: Repetitive Transcranial Magnetic Stimulation (rTMS); Device: Sham Repetitive Transcranial Stimulation (rTMS)
Sponsors: Centre for Addiction and Mental Health; Centre for Addiction and Mental Health; Canadian Institutes of Health Research (CIHR)
Recruiting - verified April 2012 - Conditions: Advanced Cancer; Healthy
Intervention:
Sponsors: University Health Network, Toronto; University Health Network, Toronto
Not yet recruiting - verified March 2012 - Conditions: Moderate to Severe Alzheimer; Alzheimer Disease
Interventions: Drug: RPh201, botanical drug product; Drug: Placebo; Drug: RPh201, botanical extract product; Drug: Placebo
Sponsors: Regenera Pharma Ltd; Regenera Pharma Ltd; Kendle Toronto, Inc, a wholly-owned subsidiary of INC Research LLC
Recruiting - verified January 2012 - Condition: Schizophrenia
Intervention: Other: Brain Stimulation via Transcranial Magnetic Stimulation
Sponsors: Centre for Addiction and Mental Health; Centre for Addiction and Mental Health; Canadian Institutes of Health Research (CIHR); National Alliance for Research on Schizophrenia and Depression
Recruiting - verified April 2012 - Condition: Epiretinal Membrane
Interventions: Procedure: Pars plana vitrectomy and epiretinal membrane peel; Procedure: ILM peel assisted by ICG; Procedure: CE-IOL
Sponsors: Sunnybrook Health Sciences Centre; Sunnybrook Health Sciences Centre
Recruiting - verified February 2012 - Conditions: Colon Cancer; Rectal Cancer
Intervention:
Sponsors: University of Michigan; University of Michigan; Early Detection Research Network
Recruiting - verified January 2012 - Condition: Pain
Interventions: Behavioral: Educational video - Active; Behavioral: Educational Video - Sham; Drug: Sucrose Placebo (water); Drug: Sucrose; Drug: Lidocaine Placebo; Drug: Lidocaine
Sponsors: The Hospital for Sick Children; The Hospital for Sick Children
Recruiting - verified December 2011 - Condition: Asthma
Interventions: Drug: AIM-102, D-cyclohexylalanine-D-glutamic-glycine tripeptide; Drug: Buffered Saline
Sponsors: AIM Therapeutics Inc.; AIM Therapeutics Inc.
Not yet recruiting - verified December 2011 - Condition: Renal Tubular Function
Intervention:
Sponsors: St. Joseph's Healthcare Hamilton; St. Joseph's Healthcare Hamilton; McMaster University
Not yet recruiting - verified December 2011 - Condition: Schizophrenia
Intervention: Device: repetitive Transcranial Magnetic Stimulation
Sponsors: Centre for Addiction and Mental Health; Centre for Addiction and Mental Health
Recruiting - verified January 2012 - Condition: Regulation of Muscle Protein Synthesis
Interventions: Dietary Supplement: whey protein; Dietary Supplement: whey protein supplemented with leucine; Dietary Supplement: whey protein supplemeted with essential amino acids
Sponsors: McMaster University; McMaster University; University of California, Davis; Canadian Institutes of Health Research (CIHR); Natural Sciences and Engineering Research Council, Canada
Completed - verified December 2011 - Condition: Intubation, Orotracheal
Interventions: Device: GlideScope Groove; Device: Control: Standard GlideScope
Sponsors: Lawson Health Research Institute; Lawson Health Research Institute; University of Western Ontario, Canada
Not yet recruiting - verified December 2011 - Condition: Intubation, Intratracheal
Interventions: Device: GlideScope Groove; Device: Control: Macintosh blade
Sponsors: Lawson Health Research Institute; Lawson Health Research Institute
Not yet recruiting - verified December 2011 - Condition: Non-anemic Iron Deficiency
Interventions: Dietary Supplement: Ferrous Sulfate; Dietary Supplement: Placebo; Other: No intervention; Behavioral: Dietary counseling
Sponsors: The Hospital for Sick Children; The Hospital for Sick Children; Canadian Institutes of Health Research (CIHR); Mead Johnson Nutrition; Mount Sinai Hospital, Canada; St. Michael's Hospital, Toronto
Not yet recruiting - verified November 2011 - Conditions: Mood Disorder; Psychotic Disorder
Intervention: Behavioral: Access to TELUS Health Space and Smart Phone
Sponsors: Lawson Health Research Institute; Lawson Health Research Institute; London Health Sciences Centre; Canadian Mental Health Association; St. Joseph's Health Care London
Not yet recruiting - verified November 2011 - Condition: Healthy Adults
Interventions: Dietary Supplement: Amino Acid Crystalline Lysine Amino Acid Mix; Dietary Supplement: Cooked Rice containing Lysine
Sponsors: The Hospital for Sick Children; The Hospital for Sick Children
Enrolling by invitation - verified November 2011 - Condition: Atrial Fibrillation
Intervention: Drug: dabigatran
Sponsors: Lawson Health Research Institute; Allan Skanes; Boehringer Ingelheim Pharmaceuticals
Not yet recruiting - verified November 2011 - Condition: Schizophrenia
Interventions: Drug: Nicotine polacrilex; Drug: Regular chewing gum; Dentyne Ice, Wrigely´s Mint Gum
Sponsors: Centre for Addiction and Mental Health; Centre for Addiction and Mental Health
Recruiting - verified January 2012 - Condition: Infections, Human Immunodeficiency Virus and Hepatitis
Interventions: Drug: Dolutegravir; Drug: Methadone
Sponsors: ViiV Healthcare; ViiV Healthcare; Shionogi; GlaxoSmithKline
Completed - verified March 2012 - Condition: Healthy
Interventions: Other: Isomaltooligosaccharide (digestion-resistant carbohydrates); Other: Isomaltooligosaccharide (digestion-resistant carbohydrates); Other: Sucrose
Sponsors: BioNeutra Inc.; BioNeutra Inc.; Alberta Agriculture and Rural Development
Active, not recruiting - verified October 2011 - Conditions: Dyslipidaemia; Insulin Resistance
Intervention: Drug: Resveratrol
Sponsors: University Health Network, Toronto; University Health Network, Toronto; Canadian Institutes of Health Research (CIHR)
Active, not recruiting - verified May 2012 - Conditions: Atherosclerosis; Coronary Artery Disease; Cardiovascular Disease
Intervention:
Sponsors: Cedars-Sinai Medical Center; Cedars-Sinai Medical Center
Recruiting - verified September 2011 - Conditions: Atherosclerosis; Carotid Artery Disease
Intervention:
Sponsors: Sunnybrook Health Sciences Centre; Sunnybrook Health Sciences Centre; Canadian Institutes of Health Research (CIHR)
Recruiting - verified September 2011 - Condition: Healthy
Interventions: Drug: Human milk-dissolved amoxicillin; Drug: Water-dissolved amoxicillin
Sponsors: The Hospital for Sick Children; The Hospital for Sick Children; World Health Organization
Active, not recruiting - verified September 2011 - Condition: Pain Due to Certain Specified Procedures
Interventions: Drug: 24% sucrose po solution; Drug: Placebo po
Sponsors: Children's Hospital of Eastern Ontario; Children's Hospital of Eastern Ontario; University of Ottawa
Not yet recruiting - verified September 2011 - Condition: Cancer
Interventions: Behavioral: Moderate Exercise Group; Behavioral: Passive Sitting Group
Sponsors: University of Western Ontario, Canada; University of Western Ontario, Canada
Recruiting - verified September 2011 - Conditions: Purpura, Thrombotic Thrombocytopenic; Hemolytic Uremic Syndrome
Intervention: Procedure: Plasma Exchange
Sponsors: London Health Sciences Centre; London Health Sciences Centre
Not yet recruiting - verified September 2011 - Condition: Postpartum Hemorrhage
Interventions: Drug: Carbetocin; Drug: Carbetocin; Drug: Carbetocin; Drug: Carbetocin; Drug: Carbetocin
Sponsors: Samuel Lunenfeld Research Institute, Mount Sinai Hospital; Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Completed - verified March 2012 - Condition: Pulmonary Arterial Hypertension
Intervention: Device: Ventripoint Medical System
Sponsors: VentriPoint Diagnostics Ltd.; VentriPoint Diagnostics Ltd.
Recruiting - verified April 2012 - Condition: Influenza
Interventions: Biological: High Dose Trivalent Inactivated Influenza Vaccine; Biological: Trivalent Inactivated Influenza Vaccine
Sponsors: Sanofi-Aventis; Sanofi-Aventis
Active, not recruiting - verified February 2012 - Condition: Cardiovascular Diseases
Interventions: Dietary Supplement: Salba hispanica L.; Dietary Supplement: Papaver somniferum L.; Dietary Supplement: Linum Usitatissimum; Dietary Supplement: Sesamum indicum; Dietary Supplement: Quaker Bran Muffin Mix
Sponsors: St. Michael's Hospital, Toronto; St. Michael's Hospital, Toronto
Active, not recruiting - verified April 2012 - Conditions: Meningococcal Disease; Meningococcal Meningitis
Intervention: Biological: Serogroup B meningococcal vaccine
Sponsors: Novartis; Novartis; Novartis Vaccines
Completed - verified January 2012 - Condition: Diabetes Prevention
Intervention: Other: FDD program
Sponsors: Lawson Health Research Institute; Lawson Health Research Institute
Not yet recruiting - verified August 2011 - Conditions: Lower Extremity Chronic Ulcers; Diabetes Mellitus
Interventions: Biological: Curexcell; Biological: Sham injection
Sponsors: Macrocure Ltd.; Macrocure Ltd.; Averion International Corporation
Recruiting - verified September 2011 - Conditions: Respiratory Tract Infections; Asthma; Avitaminosis
Interventions: Drug: Vitamin D - Cholecalciferol 400 IU; Drug: Vitamin D3 - Cholecalciferol 2000 IU
Sponsors: The Hospital for Sick Children; The Hospital for Sick Children; Mount Sinai Hospital, Canada; St. Michael's Hospital, Toronto
Recruiting - verified September 2011 - Condition: Thigh Cellulite
Intervention: Other: Cellulite reduction cream
Sponsors: Nutrasource Diagnostics Inc.; Nutrasource Diagnostics Inc.
Completed - verified March 2012 - Condition: Cancer
Interventions: Behavioral: Moderate Exercise Group; Behavioral: Passive Sitting Group
Sponsors: University of Western Ontario, Canada; University of Western Ontario, Canada
Recruiting - verified August 2011 - Condition: Obesity
Interventions: Dietary Supplement: Control; Behavioral: 750 kcal dietary restriction (soy protein group); Dietary Supplement: Soy protein group; Dietary Supplement: Whey protein group; Behavioral: 750 kcal dietary restriction (whey protein group); Behavioral: 750 kcal dietary restriction (control group)
Sponsors: McMaster University; McMaster University; National Dairy Council
Not yet recruiting - verified August 2011 - Condition: Pregnancy
Intervention: Device: Ultrasound examination
Sponsors: Lawson Health Research Institute; Lawson Health Research Institute
Recruiting - verified September 2011 - Condition: Depression
Intervention: Drug: LY2940094
Sponsors: Eli Lilly and Company; Eli Lilly and Company
Completed - verified January 2012 - Conditions: Diabetes Mellitus; Overweight; Obesity
Intervention: Dietary Supplement: Salba (Salvia hispanica L.)
Sponsors: St. Michael's Hospital, Toronto; St. Michael's Hospital, Toronto; Canadian Diabetes Association
Recruiting - verified June 2009 - Condition: Metabolic Syndrome
Intervention: Other: dietary treatment
Sponsors: University of Toronto; University of Toronto; Agriculture and Agri-Food Canada
Completed - verified July 2011 - Condition: Peanut Allergy
Interventions: Procedure: Peanut protein; Procedure: Oat flour
Sponsors: McMaster University; Hamilton Health Sciences Corporation; AllerGen NCE Inc.; McMaster University
Recruiting - verified May 2012 - Condition: Healthy
Interventions: Drug: Trazodone; Drug: Quetiapine; Drug: Pindolol; Procedure: Blood Collection
Sponsors: University of Ottawa; University of Ottawa
Recruiting - verified July 2011 - Condition: Healthy
Interventions: Dietary Supplement: cogniVida 50mg/day; Dietary Supplement: cogniVida100mg/day; Dietary Supplement: Rebaudioside-A 303.7mg/day
Sponsors: DSM Nutritional Products, Inc.; DSM Nutritional Products, Inc.
Active, not recruiting - verified August 2011 - Condition: Prediabetes
Interventions: Behavioral: PREPARE education program; Other: standard of care presentation
Sponsors: Brescia University College; Brescia University College
Recruiting - verified July 2011 - Conditions: Feasibility; Insulin; Glucose; Lipids; Eating
Interventions: Other: Sedentary; Other: Sedentary With Breaks; Other: Sedentary With Breaks and Physical Activity
Sponsors: Children's Hospital of Eastern Ontario; Children's Hospital of Eastern Ontario; University of Ottawa
Recruiting - verified April 2012 - Condition: Myocardial Ischemia
Intervention: Radiation: 18F-Fluorodeoxyglucose
Sponsors: University of Ottawa Heart Institute; University of Ottawa Heart Institute
Recruiting - verified March 2012 - Condition: Gout
Intervention: Drug: Arhalofenat4e
Sponsors: Metabolex; Metabolex
Active, not recruiting - verified November 2011 - Condition: Clostridium Difficile Infection
Interventions: Procedure: Fecal Transplantation; Drug: Vancomycin
Sponsors: McMaster University; McMaster University; St. Joseph's Healthcare Hamilton
Not yet recruiting - verified July 2011 - Condition: Gestational Diabetes
Intervention:
Sponsors: University of Toronto; University of Toronto; Canadian Diabetes Association; Canadian Foundation for Dietetic Research (CFDR)
Active, not recruiting - verified July 2011 - Condition: Fat Reduction in the Upper Arm
Intervention: Device: The Zeltiq System
Sponsors: Zeltiq Aesthetics; Zeltiq Aesthetics
Completed - verified March 2012 - Condition: Normative Data Study of Joints of Healthy Children
Intervention:
Sponsors: Children's Hospital of Eastern Ontario; Children's Hospital of Eastern Ontario; Abbott
Enrolling by invitation - verified June 2011 - Condition: Osteoporosis
Interventions: Drug: Nitrates; Other: Placebo
Sponsors: University of Toronto; University of Toronto; The Physicians' Services Incorporated Foundation; California Pacific Medical Center; Sunnybrook Health Sciences Centre
Not yet recruiting - verified June 2011 - Condition: Smoking Cessation
Interventions: Other: acupuncture; Other: acupuncture
Sponsors: Queen's University; Queen's University
Not yet recruiting - verified July 2011 - Condition: Colorectal Cancer
Interventions: Behavioral: Health counselling by nurse navigator; Behavioral: Usual primary care counselling
Sponsors: Cancer Care Ontario; Cancer Care Ontario; Canadian Institutes of Health Research (CIHR)
Recruiting - verified January 2012 - Condition: Diabetes Mellitus, Type 2
Interventions: Drug: Linagliptin Single Tablet; Drug: Metformin Single Tablet; Drug: Linagliptin/Metformin Combo
Sponsors: Boehringer Ingelheim Pharmaceuticals; Boehringer Ingelheim Pharmaceuticals
Completed - verified May 2012 - Condition: Pain
Interventions: Device: Pulsed electromagnetic field device (ActiPatch TM); Device: Inactive pulsed electromagnetic field device (ActiPatch TM)
Sponsors: Samuel Lunenfeld Research Institute, Mount Sinai Hospital; Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Terminated - verified March 2012 - Condition: Cat Allergy
Intervention: Biological: Cat-PAD
Sponsors: Circassia Limited; Circassia Limited; Adiga Life Sciences
Recruiting - verified May 2012 - Condition: Cat Allergy
Intervention: Biological: Cat-PAD
Sponsors: Circassia Limited; Circassia Limited; Adiga Life Sciences
Recruiting - verified May 2012 - Condition: Meibomian Gland Dysfunction
Intervention:
Sponsors: University of Waterloo; University of Waterloo
Recruiting - verified June 2011 - Conditions: Cervical Cancer; HPV Type 16/18 Infections
Intervention: Biological: GSK Biologicals' HPV vaccine 580299
Sponsors: GlaxoSmithKline; GlaxoSmithKline
Active, not recruiting - verified March 2012 - Condition: Insulin Resistance
Interventions: Dietary Supplement: Novel dietary fiber; Dietary Supplement: Novel dietary fiber; Other: Placebo
Sponsors: Cargill; Cargill
Completed - verified June 2011 - Condition: Fat Reduction in the Abdomen
Intervention: Device: The Zeltiq System
Sponsors: Zeltiq Aesthetics; Zeltiq Aesthetics
Completed - verified January 2012 - Condition: Satiety
Intervention: Other: Yogurt
Sponsors: University of Guelph; University of Guelph
Not yet recruiting - verified June 2011 - Condition: Vaccine Exposure During Pregnancy
Intervention:
Sponsors: Dalhousie University; Dalhousie University; Li Ka Shing Foundation; PHAC/CIHR Influenza Research Network
Active, not recruiting - verified June 2011 - Condition: Cardiac Arrest
Intervention: Procedure: Bystander CPR using 30:2 ratio versus continuous compression
Sponsors: Ottawa Hospital Research Institute; Ottawa Hospital Research Institute
Completed - verified March 2012 - Condition: Clostridium Difficile Infection
Intervention: Biological: "synthetic stool" or pure cultures of probiotic intestinal bacteria
Sponsors: Queen's University; Queen's University; The Physicians' Services Incorporated Foundation
Recruiting - verified April 2012 - Condition: White Blood Cells in Tears
Interventions: Device: Lotrafilcon A contact lens; Device: Lotrafilcon B contact lens
Sponsors: CIBA VISION; CIBA VISION; University of Waterloo
Completed - verified March 2012 - Condition: Aluminum Contamination of Parenteral Nutrition
Intervention:
Sponsors: The Hospital for Sick Children; The Hospital for Sick Children
Recruiting - verified June 2011 - Condition: Physical Activity
Interventions: Behavioral: Transformational Teaching; Behavioral: Standard Educational Practices
Sponsors: University of British Columbia; University of British Columbia; Canadian Institutes of Health Research (CIHR)
Not yet recruiting - verified January 2012 - Condition: Breast Lesions
Intervention:
Sponsors: Hamilton Health Sciences Corporation; Hamilton Health Sciences Corporation
Recruiting - verified April 2012 - Condition: Influenza Vaccine
Interventions: Biological: Agriflu; Biological: Fluad; Biological: Intanza; Biological: Vaxigrip
Sponsors: University of British Columbia; University of British Columbia; PHAC/CIHR Influenza Research Network
Active, not recruiting - verified March 2012 - Condition: Spinal Cord Injury
Intervention: Behavioral: Exercise prescription following the physical activity guidelines for people with spinal cord injury
Sponsors: McMaster University; McMaster University; Rick Hansen Foundation
Not yet recruiting - verified June 2011 - Condition: Dysphagia
Interventions: Behavioral: Tongue Pressure Profile Training; Behavioral: Tongue-Pressure Strength-and-Accuracy Training
Sponsors: Toronto Rehabilitation Institute; Toronto Rehabilitation Institute
Not yet recruiting - verified June 2011 - Conditions: Dyslipidemia; Diabetes; Prediabetes; Dysglycemia; Overweight; Obesity; Gout; Hypertension; Non-alcoholic Fatty Liver Disease; Metabolic Syndrome; Cardiovascular Disease
Intervention: Other: Dietary fructose
Sponsors: University of Toronto; University of Toronto; Canadian Institutes of Health Research (CIHR); Canada Research Chair Endowment of the Federal Government of Canada; Calorie Control Council
Active, not recruiting - verified April 2012 - Condition: Healthy
Interventions: Genetic: Dietary advice with genetic information; Other: General dietary recommendations
Sponsors: University of Toronto; University of Toronto; Advanced Foods and Materials Network
Enrolling by invitation - verified March 2011 - Condition: Diabetes
Interventions: Behavioral: Peer Modeling; Behavioral: Control
Sponsors: University of Western Ontario, Canada; University of Western Ontario, Canada
Recruiting - verified June 2011 - Conditions: Obesity; Overweight
Interventions: Other: Low dairy; Other: High dairy
Sponsors: University of Guelph; University of Guelph; Purdue University; University of Saskatchewan
Withdrawn - verified August 2011 - Condition: Sexual Assault
Interventions: Behavioral: Enhanced AAA Sexual Assault Resistance Education; Behavioral: Brochure
Sponsors: University of Windsor; University of Windsor; Canadian Institutes of Health Research (CIHR)
Recruiting - verified September 2011 - Condition: Influenza
Intervention:
Sponsors: Dalhousie University; Dalhousie University; Canadian Institutes of Health Research (CIHR)
Active, not recruiting - verified June 2011 - Condition: Healthy
Intervention: Device: 25G x 1" Needle Autoinjector
Sponsors: Biogen Idec; Biogen Idec
Terminated - verified August 2011 - Condition: Pandemic H5N1 Influenza
Interventions: Biological: GSK Biologicals' investigational vaccine GSK1557484A; Biological: Placebo
Sponsors: GlaxoSmithKline; GlaxoSmithKline
Completed - verified January 2012 - Condition: Tobacco Use Disorder
Intervention:
Sponsors: Centre for Addiction and Mental Health; Centre for Addiction and Mental Health; Pfizer
Recruiting - verified March 2012 - Condition: Anorexia Nervosa
Interventions: Drug: RhIGF-1 with transdermal 17-beta estradiol; Drug: Placebo and transdermal 17-beta estradiol
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; The Hospital for Sick Children
Recruiting - verified February 2012 - Condition: Intraocular Pressure
Intervention: Device: RespirAct
Sponsors: University of Toronto; University of Toronto; University Health Network, Toronto; Thornhill Research Inc.
Not yet recruiting - verified November 2010 - Condition: Normal Contact Lens Wearers.
Interventions: Device: Multi-purpose disinfecting solution; Device: Clear Care; Device: Opti-Free RepleniSH
Sponsors: Abbott Medical Optics; Abbott Medical Optics
Completed - verified May 2012 - Condition: Huntington's Disease
Intervention:
Sponsors: CHDI Foundation, Inc.; CHDI Foundation, Inc.; Monash University
Recruiting - verified February 2012 - Condition: Hot Flashes
Interventions: Device: Menopod cooling device; Device: Inactive device
Sponsors: Queen's University; Queen's University; Menopod Corp.
Withdrawn - verified February 2012 - Condition: Hypertension
Interventions: Drug: Telmisartan/Amlodipine Combination Tablet; Drug: Amlodipine Monocomponent
Sponsors: Boehringer Ingelheim Pharmaceuticals; Boehringer Ingelheim Pharmaceuticals
Completed - verified March 2012 - Condition: Study Focus is to Define the Usual Gut Microbiota Following Prebiotic Feeding
Interventions: Dietary Supplement: Prebiotic; Dietary Supplement: Prebiotic
Sponsors: Guelph Food Research Centre; Dan Ramdath; Health Canada; Advanced Foods and Materials Network; University of Ontario Institute of Technology; University of Lethbridge
Active, not recruiting - verified February 2012 - Condition: Wrinkles
Interventions: Drug: onabotulinumtoxinA; Drug: JUVÉDERM
Sponsors: AboutSkin Dermatology and DermSurgery, PC; AboutSkin Dermatology and DermSurgery, PC; Allergan
Active, not recruiting - verified September 2011 - Condition: Major Depressive Disorder
Interventions: Drug: LY2940094; Drug: Placebo
Sponsors: Eli Lilly and Company; Eli Lilly and Company
Completed - verified November 2011 - Condition: Postpartum Hemorrhage
Interventions: Drug: Carbetocin; Drug: Carbetocin; Drug: Carbetocin; Drug: Carbetocin; Drug: Carbetocin
Sponsors: Samuel Lunenfeld Research Institute, Mount Sinai Hospital; Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Completed - verified September 2011 - Condition: Glaucoma
Interventions: Device: portable CCTV; Device: Telescopes, telemicroscopes and microscopes; Device: Absorptive filters
Sponsors: Lawson Health Research Institute; Lawson Health Research Institute; Pfizer
Recruiting - verified August 2011 - Condition: Use of Research Evidence
Intervention: Other: SHARE (Synthesized HIV/AIDS Research Evidence)
Sponsors: Ontario HIV Treatment Network; Ontario HIV Treatment Network; McMaster University
Active, not recruiting - verified December 2011 - Condition: Central Venous Pressure
Interventions: Device: Non-Invasive Central Venous Pressure monitor; Procedure: Physical examination of jugular vein
Sponsors: Mespere Lifesciences Inc.; Mespere Lifesciences Inc.; St. Joseph's Healthcare Hamilton
Enrolling by invitation - verified January 2012 - Conditions: Virus Diseases; RNA Virus Infections; Respiratory Tract Diseases; Respiratory Tract Infections
Interventions: Biological: 20 micrograms dose H5 VLP; Biological: 30 micrograms dose H5 VLP; Biological: 45 micrograms dose H5 VLP; Biological: 45 micrograms non-adjuvanted H5 VLP; Biological: Placebo
Sponsors: Medicago; Medicago; INC Research
Active, not recruiting - verified June 2011 - Conditions: Cognition - Other; Ageing
Interventions: Behavioral: Memory training; Behavioral: Control Workshop
Sponsors: Baycrest; Baycrest; Cogniciti Inc.
Withdrawn - verified October 2011 - Condition: Prostate Cancer
Intervention: Radiation: PET scan and ultrasound
Sponsors: University of Ottawa Heart Institute; University of Ottawa Heart Institute; Prostate Cancer Research Foundation of Canada
Active, not recruiting - verified January 2012 - Conditions: Mild Cognitive Impairment (MCI); Alzheimer's Disease
Intervention:
Sponsors: Alzheimer's Disease Cooperative Study (ADCS); Alzheimer's Disease Cooperative Study (ADCS); Northern California Institute for Research and Education (NCIRE); National Institute on Aging (NIA)
Recruiting - verified May 2012 - Condition: Nicotine Dependence
Interventions: Drug: Baclofen 30 mg/day; Drug: placebo pill; Drug: Baclofen 60 mg/day
Sponsors: Centre for Addiction and Mental Health; Centre for Addiction and Mental Health; Canadian Tobacco Control Research Initiative
Recruiting - verified December 2011 - Conditions: Hypertrophic Cardiomyopathy; Hearing Loss; Oncology
Intervention: Device: GeneInsight Clinic (GIC)
Sponsors: Brigham and Women's Hospital; Brigham and Women's Hospital; National Institutes of Health (NIH); National Library of Medicine (NLM)
Active, not recruiting - verified May 2012 - Condition: Influenza
Interventions: Biological: Intanza; Biological: Intanza
Sponsors: Dalhousie University; Dalhousie University; IWK Health Centre; Sanofi Pasteur MSD; Mount Sinai Hospital, Canada
Completed - verified June 2011 - Condition: Healthy Young and Elderly Volunteers
Interventions: Drug: Intravenous Citalopram; Drug: Normal Saline
Sponsors: Rotman Research Institute at Baycrest; Rotman Research Institute at Baycrest; Centre for Addiction and Mental Health; University of Toronto
Recruiting - verified January 2012 - Condition: Back Pain
Intervention:
Sponsors: Canadian Memorial Chiropractic College; Canadian Memorial Chiropractic College
Recruiting - verified June 2011 - Condition: Changes in EEG During and After Magnetic Stimulation
Interventions: Device: true left high frequency; Device: Passive sham left high frequency
Sponsors: St. Joseph's Healthcare Hamilton; St. Joseph's Healthcare Hamilton
Completed - verified July 2007 - Condition: Influenza
Interventions: Behavioral: Standard Education Only; Behavioral: Standard Education Plus OIDA
Sponsors: Ottawa Hospital Research Institute; Ottawa Hospital Research Institute; Élisabeth Bruyère Research Institute; Providence Care; Canadian Center for Vaccinology; Canadian Institutes of Health Research (CIHR)
Completed - verified October 2011 - Condition: Influenza
Interventions: Behavioral: Intervention Group; Behavioral: Control Group
Sponsors: Ottawa Hospital Research Institute; Ottawa Hospital Research Institute; Élisabeth Bruyère Research Institute; Canadian Center for Vaccinology
Recruiting - verified July 2011 - Conditions: Vertebral Artery Dissection; Cerebrovascular Accident; Cerebrovascular Stroke
Intervention: Other: head positions and spinal manipulation
Sponsors: Canadian Memorial Chiropractic College; Canadian Memorial Chiropractic College; Canadian Chiropractic Protective Association; NCMIC
Not yet recruiting - verified June 2011 - Conditions: Influenza, Human; Seasonal Influenza
Interventions: Biological: Quadrivalent seasonal influenza vaccine GSK2282512A; Biological: Fluarix®; Biological: Fluarix-YB; Biological: Quadrivalent seasonal influenza vaccine GSK2282512A
Sponsors: GlaxoSmithKline; GlaxoSmithKline
Completed - verified August 2011 - Conditions: Insomnia; Chronic Pain
Interventions: Behavioral: Sleep diary; Behavioral: Self-help manual for insomnia
Sponsors: Ottawa Hospital Research Institute; Ottawa Hospital Research Institute; The Ottawa Hospital
Active, not recruiting - verified March 2012 - Condition: Total Knee Replacement
Intervention:
Sponsors: Ottawa Hospital Research Institute; Ottawa Hospital Research Institute
Recruiting - verified December 2011 - Conditions: Femoroacetabular Impingement; Cartilage, Articular; Hip Joint; MRI
Interventions: Procedure: MRI; Procedure: MRI
Sponsors: Ottawa Hospital Research Institute; Ottawa Hospital Research Institute
Active, not recruiting - verified April 2012 - Condition: Osteoarthritis
Intervention:
Sponsors: Smith & Nephew, Inc.; Smith & Nephew, Inc.; Jason Jones, MS, Group Director, Clinical Affairs, Smith&Nephew
Recruiting - verified August 2011 - Condition: Major Depressive Disorder (MDD)
Interventions: Behavioral: Mindfulness Based Cognitive Therapy (MBCT); Behavioral: Cognitive Behavioral Therapy (CBT)
Sponsors: Centre for Addiction and Mental Health; Centre for Addiction and Mental Health; University of Toronto
Recruiting - verified July 2011 - Condition: Meningococcal Infections
Interventions: Biological: Meningococcal vaccine GSK 134612; Biological: Menactra®
Sponsors: GlaxoSmithKline; GlaxoSmithKline
Completed - verified June 2011 - Condition: Aged
Intervention: Behavioral: Real world strategy approach
Sponsors: Baycrest; Baycrest
Completed - verified March 2012 - Condition: Herpes Zoster
Interventions: Biological: Herpes Zoster Vaccine GSK1437173A; Biological: Placebo
Sponsors: GlaxoSmithKline; GlaxoSmithKline
Active, not recruiting - verified April 2012 - Condition: Herpes Zoster
Interventions: Biological: Herpes Zoster Vaccine GSK1437173A; Biological: Placebo
Sponsors: GlaxoSmithKline; GlaxoSmithKline
Active, not recruiting - verified April 2012 - Conditions: Upper Respiratory Tract Infections; Rhinovirus; Infections
Interventions: Dietary Supplement: cholecalciferol (vitamin D3); Behavioral: Gargling; Dietary Supplement: Placebo
Sponsors: St. Joseph's Healthcare Hamilton; St. Joseph's Healthcare Hamilton; McMaster University
Completed - verified March 2012 - Conditions: Osteoporosis; Breast Cancer
Intervention:
Sponsors: University Health Network, Toronto; University Health Network, Toronto; Canadian Breast Cancer Research Alliance
Active, not recruiting - verified June 2010 - Condition: Healthy
Intervention: Device: IonCLeanse Footbath
Sponsors: The Canadian College of Naturopathic Medicine; The Canadian College of Naturopathic Medicine
Completed - verified November 2011 - Condition: Cancer
Intervention:
Sponsors: St. Jude Children's Research Hospital; St. Jude Children's Research Hospital; National Cancer Institute (NCI); Fred Hutchinson Cancer Research Center; Nationwide Children's Hospital; M.D. Anderson Cancer Center; University of Southern California; Children's Hospital Medical Center, Cincinnati
Recruiting - verified April 2012 - Condition: Generalized Anxiety Disorder
Interventions: Drug: Duloxetine; Drug: Placebo
Sponsors: Eli Lilly and Company; Eli Lilly and Company
Recruiting - verified May 2012 - Conditions: Asthma; Allergic Rhinitis
Intervention:
Sponsors: University of British Columbia; University of British Columbia; Allergy, Genes and Environment Network (AllerGen); Networks of Centres of Excellence (NCE)
Recruiting - verified November 2011 - Condition: Healthy
Intervention: Drug: Desvenlafaxine succinate
Sponsors: University of Ottawa; University of Ottawa
Recruiting - verified April 2010 - Condition: Diabetes, Gestational
Intervention: Other: Nutrition education
Sponsors: University of Toronto; University of Toronto
Active, not recruiting - verified April 2010 - Condition: Dermatitis, Atopic
Intervention: Drug: WBI-1001
Sponsors: Welichem Biotech Inc.; Welichem Biotech Inc.
Completed - verified June 2011 - Conditions: Schizophrenia; Schizoaffective Disorder
Intervention: Drug: Varenicline
Sponsors: Centre for Addiction and Mental Health; Centre for Addiction and Mental Health; Pfizer
Recruiting - verified March 2012 - Conditions: Haemophilus Influenzae Type b; Poliomyelitis; Hepatitis B; Serogroup C Meningococcal Diseases; Diphtheria; Pertussis; Pneumococcal Diseases; Tetanus
Interventions: Biological: GSK2202083A vaccine; Biological: Prevenar 13®; Biological: Infanrix hexa™; Biological: Menjugate®; Biological: Rotarix™
Sponsors: GlaxoSmithKline; GlaxoSmithKline
Completed - verified October 2011 - Condition: Breast Cancer
Intervention: Dietary Supplement: FemMED Breast Health Formula
Sponsors: Nutrasource Diagnostics Inc.; Nutrasource Diagnostics Inc.
Completed - verified March 2012 - Conditions: Bipolar Disorder; Cyclothymia; Borderline Personality Disorder
Intervention: Other: Mental health telemetry (MHT)
Sponsors: Sunnybrook Health Sciences Centre; Sunnybrook Health Sciences Centre; Motorola Canada Limited
Completed - verified April 2012 - Conditions: Mild Cognitive Impairment; Alzheimer's Disease
Intervention:
Sponsors: Alzheimer's Disease Cooperative Study (ADCS); Alzheimer's Disease Cooperative Study (ADCS); Northern California Institute for Research and Education (NCIRE); National Institute on Aging (NIA)
Recruiting - verified February 2012 - Condition: Onychomycosis
Interventions: Drug: Terbinafine Hydrochloride; Other: Purified Water
Sponsors: Nitric BioTherapeutics, Inc; Nitric BioTherapeutics, Inc
Active, not recruiting - verified June 2011 - Condition: Familial Hypercholesterolaemia
Interventions: Drug: rosuvastatin calcium; Drug: rosuvastatin calcium; Drug: rosuvastatin calcium
Sponsors: AstraZeneca; AstraZeneca
Active, not recruiting - verified March 2012 - Condition: Pulmonary Disease, Chronic Obstructive
Interventions: Drug: Tiotropium; Drug: Tiotropium; Drug: Placebo
Sponsors: Boehringer Ingelheim Pharmaceuticals; Boehringer Ingelheim Pharmaceuticals; Pfizer
Completed - verified May 2012 - Condition: Obstructive Sleep Apnea
Intervention:
Sponsors: Doctor's Directive Strategies Inc.; Doctor's Directive Strategies Inc.
Completed - verified December 2011 - Condition: Sarcopenia
Intervention: Dietary Supplement: Whey or soy protein
Sponsors: McMaster University; McMaster University; National Dairy Council
Completed - verified July 2011 - Conditions: Early Inflammatory Arthritis; Chronic Disease
Intervention: Behavioral: peer mentor training
Sponsors: Sunnybrook Health Sciences Centre; Sunnybrook Health Sciences Centre; Canadian Arthritis Network
Completed - verified December 2011 - Conditions: Early Inflammatory Arthritis; Chronic Disease
Intervention: Behavioral: peer support
Sponsors: Sunnybrook Health Sciences Centre; Sunnybrook Health Sciences Centre; Canadian Arthritis Network
Completed - verified December 2011 - Conditions: Autoantibody Positive; Non-diabetic Relatives at Risk for Type 1 Diabetes; High Risk; Impaired Glucose Tolerance
Intervention: Drug: Teplizumab
Sponsors: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); National Center for Research Resources (NCRR); Juvenile Diabetes Research Foundation; American Diabetes Association
Recruiting - verified February 2012 - Conditions: LDL Cholesterol; Triglycerides
Interventions: Dietary Supplement: Placebo; Dietary Supplement: Investigational Product 1; Dietary Supplement: Investigational Product 2
Sponsors: Nutrasource Diagnostics Inc.; Nutrasource Diagnostics Inc.; Nordic Naturals
Completed - verified March 2012 - Conditions: Tobacco Use Disorder; Smoking; Smoking Cessation
Interventions: Drug: bupropion; Drug: varenicline; Behavioral: motivational emails
Sponsors: Centre for Addiction and Mental Health; Centre for Addiction and Mental Health; Ontario Ministry of Health Promotion & Sport
Active, not recruiting - verified September 2011 - Condition: Peptic Ulcer Disease
Interventions: Drug: Esomeprazole/ASA Fixed Combination; Drug: Esomeprazole; Drug: ASA
Sponsors: AstraZeneca; AstraZeneca
Terminated - verified January 2012 - Conditions: Pregnancy; Fertility
Intervention: Behavioral: Creighton Model System of Natural Family Planning
Sponsors: University of Utah; University of Utah; Department of Health and Human Services
Active, not recruiting - verified December 2011 - Conditions: Pain; Anxiety
Interventions: Drug: Liposomal lidocaine; Drug: Vapocoolant spray; Other: Rubbing adjacent to the injection site; Other: Distraction
Sponsors: The Hospital for Sick Children; The Hospital for Sick Children
Completed - verified July 2011 - Condition: Idiopathic Intracranial Hypertension
Interventions: Drug: Acetazolamide; Drug: Placebo; Behavioral: Formal weight loss counselling program
Sponsors: St. Luke's-Roosevelt Hospital Center; St. Luke's-Roosevelt Hospital Center; National Eye Institute (NEI); University of Rochester; University of Iowa; University of California, Davis
Recruiting - verified May 2012 - Condition: Influenza
Interventions: Biological: Fluviral influenza vaccine, 2009-2010; Biological: Normal saline
Sponsors: Mount Sinai Hospital, Canada; Mount Sinai Hospital, Canada; GlaxoSmithKline
Completed - verified April 2012 - Condition: Diabetic Neuropathy
Intervention: Procedure: Nerve conduction study and Ultrasound of the PTN
Sponsors: University Health Network, Toronto; University Health Network, Toronto
Recruiting - verified November 2011 - Condition: Influenza Infection
Interventions: Biological: GSK2340274A; Biological: GSK2340273A; Biological: Saline placebo
Sponsors: GlaxoSmithKline; GlaxoSmithKline
Completed - verified June 2011 - Conditions: Neck Pain; Shoulder Pain
Interventions: Device: InterX 5000; Device: InterX 5000
Sponsors: Canadian Memorial Chiropractic College; Canadian Memorial Chiropractic College; McMaster University
Completed - verified June 2011 - Condition: Hypercholesterolemia
Interventions: Dietary Supplement: Wheat bran; Dietary Supplement: 3g high MW; Dietary Supplement: 4g medium MW; Dietary Supplement: 3g medium MW; Dietary Supplement: 4g low MW
Sponsors: Glycemic Index Laboratories, Inc; Glycemic Index Laboratories, Inc; CreaNutrition, AG; University of Guelph; University of Sydney; Laval University; Reading Scientific Services, Ltd.; University of Toronto; Agriculture and Agri-Food Canada
Completed - verified June 2011 - Condition: Influenza Infection
Interventions: Biological: GSK2340274A; Biological: GSK2340273A
Sponsors: GlaxoSmithKline; GlaxoSmithKline
Completed - verified April 2011 - Condition: Influenza Infection
Interventions: Biological: GSK2340274A; Biological: GSK2340273A
Sponsors: GlaxoSmithKline; GlaxoSmithKline
Completed - verified January 2012 - Condition: Arthropathy of Knee Joint
Interventions: Procedure: Total Knee Arthroplasty; Procedure: Motion analysis
Sponsors: Ottawa Hospital Research Institute; Ottawa Hospital Research Institute; Wright Medical Technology
Not yet recruiting - verified December 2011 - Condition: Heart Failure
Interventions: Dietary Supplement: Vitamin B1; Dietary Supplement: Placebo
Sponsors: St. Michael's Hospital, Toronto; St. Michael's Hospital, Toronto; Heart and Stroke Foundation of Ontario
Recruiting - verified September 2011 - Condition: Healthy
Interventions: Drug: Oxymorphone ER; Drug: Oxycodone CR; Drug: Placebo; Drug: Hydromorphone
Sponsors: Endo Pharmaceuticals; Endo Pharmaceuticals; Kendle Early Stages Toronto
Completed - verified July 2011 - Condition: Heart Failure
Intervention:
Sponsors: St. Michael's Hospital, Toronto; St. Michael's Hospital, Toronto; Canadian Foundation for Dietetic Research (CFDR)
Recruiting - verified September 2011 - Conditions: Obesity; Metabolic Syndrome; Cardiovascular Disease
Interventions: Other: Exercise: LVLI; Other: Exercise: HVLI; Other: Exercise: LVHI
Sponsors: Queen's University; Queen's University; Canadian Institutes of Health Research (CIHR)
Recruiting - verified March 2012 - Condition: Postpartum Hemorrhage
Interventions: Drug: Oxytocin; Drug: Ergonovine; Drug: Carboprost; Drug: Oxytocin and Ergonovine; Drug: Oxytocin and Carboprost
Sponsors: Samuel Lunenfeld Research Institute, Mount Sinai Hospital; Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Recruiting - verified September 2011 - Conditions: Herpes Simplex Type Two Infection; HIV Infections
Interventions: Drug: Valacyclovir; Drug: Placebo
Sponsors: University of Toronto; University of Toronto
Completed - verified March 2012 - Conditions: Glomerular Filtration Rate; Renal Blood Flow
Intervention: Procedure: Inulin and PAH clearance and MRI
Sponsors: University Health Network, Toronto; University Health Network, Toronto
Completed - verified January 2012 - Conditions: Prostate Cancer; Sexual Dysfunction
Interventions: Drug: tadalafil; Other: placebo
Sponsors: National Cancer Institute (NCI); Radiation Therapy Oncology Group; National Cancer Institute (NCI)
Active, not recruiting - verified February 2012 - Condition: Allergic Rhinitis
Interventions: Biological: Placebo; Biological: VAK694; Drug: Fluticasone
Sponsors: Novartis; Novartis Pharmaceuticals
Completed - verified May 2012 - Condition: Depression
Intervention: Drug: Zoloft (antidepressant)
Sponsors: St. Michael's Hospital, Toronto; St. Michael's Hospital, Toronto
Completed - verified May 2011 - Condition: Diabetes
Intervention: Other: P-PROMPT
Sponsors: St. Joseph's Healthcare Hamilton; St. Joseph's Healthcare Hamilton
Active, not recruiting - verified July 2011 - Conditions: Facet Joint Pain; Neck Pain
Intervention: Procedure: cervical medial branch blocks using the Quincke spinal needle
Sponsors: McMaster University; Hamilton Health Sciences Corporation; McMaster University
Not yet recruiting - verified January 2011 - Conditions: Major Depressive Disorder; Menopausal Staging and Vasomotor Symptoms (for Females)
Intervention: Drug: Desvenlafaxine Succinate
Sponsors: McMaster University; Hamilton Health Sciences Corporation; Wyeth is now a wholly owned subsidiary of Pfizer; St. Joseph's Healthcare Hamilton; McMaster University
Recruiting - verified April 2009 - Condition: Major Depressive Disorder
Intervention: Drug: Duloxetine
Sponsors: McMaster University; Hamilton Health Sciences Corporation; Eli Lilly and Company; St. Joseph's Healthcare Hamilton; McMaster University
Recruiting - verified June 2009 - Condition: Primary Dysmenorrhea
Interventions: Drug: Estradiol valerate, Dienogest (Natazia, Qlaira, BAY86-5027); Drug: Ethinyl estradiol, Levonorgestrel (Miranova)
Sponsors: Bayer; Bayer
Completed - verified January 2012 - Intracervical Catheters for Induction of Labour in Women With Prelabour Rupture of Membranes at TermConditions: Fetal Membranes, Premature Rupture; Induced Labor
Interventions: Procedure: Intracervical Balloon Catheter; Drug: Oxytocin
Sponsors: McMaster University; McMaster University; St. Joseph's Healthcare Hamilton
Terminated - verified July 2011 - Conditions: Open-Angle Glaucoma; Ocular Hypertension
Interventions: Drug: DuoTrav (travoprost-timolol ophthalmic drops); Drug: Xalacom (latanoprost-timolol ophthalmic drops)
Sponsors: Ophthalmic Consultants Centres, Canada; Ophthalmic Consultants Centres, Canada; Alcon Laboratories
Completed - verified April 2009 - Condition: Thalassemia
Intervention:
Sponsors: National Heart, Lung, and Blood Institute (NHLBI); National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified April 2012 - Condition: Diabetic Ulcer
Interventions: Device: Topical wound oxygen therapy; Device: Topical wound oxygen Placebo
Sponsors: AOTI Ltd.; AOTI Ltd.
Terminated - verified February 2012 - Condition: Heart Failure
Intervention:
Sponsors: Medtronic Cardiac Rhythm Disease Management; Medtronic Cardiac Rhythm Disease Management
Recruiting - verified December 2011 - Conditions: Colorectal Cancer; Colon Cancer; Adenomatous Polyps
Interventions: Other: Fecal occult blood test; Procedure: Virtual colonoscopy; Procedure: Optical colonoscopy
Sponsors: McMaster University; Hamilton Health Sciences Corporation; McMaster University
Terminated - verified January 2012 - Conditions: Childhood Obesity; Childhood Obstructive Sleep Apnea
Intervention:
Sponsors: Katz, Sherri Lynne, M.D.; Katz, Sherri Lynne, M.D.
Recruiting - verified July 2011 - Condition: Scoliosis
Interventions: Procedure: Surgical intervention; Other: Non operative intervention
Sponsors: Washington University School of Medicine; Washington University School of Medicine; National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS); Northwestern University; New York University; University of Virginia; University of Louisville; Maryland Spine Center; Hospital for Special Surgery, New York; University Health Network, Toronto; Hopital du Sacre', Montreal University; Dartmouth-Hitchcock Medical Center
Recruiting - verified April 2012 - Condition: Hypertension
Intervention: Behavioral: Mindfulness Based Stress Reduction (MBSR) Therapy
Sponsors: Sunnybrook Health Sciences Centre; Sunnybrook Health Sciences Centre; University Health Network, Toronto
Active, not recruiting - verified January 2012 - Condition: Asthma
Interventions: Drug: TPI ASM8; Drug: TPI ASM8; Drug: TPI ASM8; Drug: TPI ASM8
Sponsors: Topigen Pharmaceuticals; Topigen Pharmaceuticals
Completed - verified June 2011 - Conditions: Smoking Cessation; Insurance Coverage
Interventions: Other: Full Smoking Cessation Treatment Coverage (100%); Other: No Smoking Cessation Treatment Coverage (0%)
Sponsors: Pfizer; Pfizer
Completed - verified February 2012 - Conditions: Triage; Pediatrics
Intervention:
Sponsors: St. Justine's Hospital; St. Justine's Hospital; SickKids Foundation; Canadian Institutes of Health Research (CIHR)
Completed - verified July 2011 - Condition: Tuberculosis
Interventions: Biological: Ad5Ag85A; Biological: Ad5Ag85A
Sponsors: McMaster University; McMaster University
Recruiting - verified October 2011 - Condition: BACTERIAL VAGINOSIS
Intervention:
Sponsors: St. Michael's Hospital, Toronto; St. Michael's Hospital, Toronto
Active, not recruiting - verified December 2008 - Condition: Human Papillomavirus (HPV) Type 16/18 Infections and Cervical Neoplasia.
Intervention: Biological: GSK580299, GSK Biological's HPV vaccine
Sponsors: GlaxoSmithKline; GlaxoSmithKline
Active, not recruiting - verified April 2012 - Condition: Influenza
Interventions: Biological: Fluviral; Drug: Zanamivir
Sponsors: Mount Sinai Hospital, Canada; Mount Sinai Hospital, Canada; GlaxoSmithKline
Completed - verified August 2011 - Condition: Postpartum Depression
Intervention:
Sponsors: St. Michael's Hospital, Toronto; St. Michael's Hospital, Toronto
Enrolling by invitation - verified October 2008 - Condition: Influenza Virus
Interventions: Biological: GSK Biologicals' influenza vaccine GSK1557482A; Biological: Vaxigrip
Sponsors: GlaxoSmithKline; GlaxoSmithKline
Completed - verified November 2011 - Condition: Obesity
Interventions: Drug: TTP435; Drug: Placebo
Sponsors: TransTech Pharma; TransTech Pharma
Completed - verified June 2011 - Condition: Social Anxiety Disorder
Interventions: Drug: Seroquel; Drug: Sugar Pill
Sponsors: START Clinic for Mood and Anxiety Disorders; START Clinic for Mood and Anxiety Disorders; AstraZeneca
Active, not recruiting - verified July 2010 - Condition: Gastroenteritis
Interventions: Drug: Lacidophil (experimental high dose); Drug: Lacidophil (experimental standard dose); Drug: Placebo
Sponsors: The Hospital for Sick Children; The Hospital for Sick Children
Recruiting - verified May 2012 - Conditions: Locally Advanced Breast Cancer; Breast Cancer
Intervention:
Sponsors: University Health Network, Toronto; University Health Network, Toronto
Recruiting - verified September 2011 - Condition: Contraception
Interventions: Drug: Qlaira (BAY86-5027, SH T00658ID); Drug: Ortho Tri Cyclen Lo
Sponsors: Bayer; Bayer
Completed - verified July 2011 - Condition: Influenza Disease
Interventions: Biological: GSK Bio's influenza vaccine GSK2186877A; Biological: Fluarix TM
Sponsors: GlaxoSmithKline; GlaxoSmithKline
Completed - verified January 2012 - Conditions: Major Depressive Disorder; Insomnia; Hot Flashes
Intervention: Drug: Quetiapine Extended Release
Sponsors: McMaster University; McMaster University
Completed - verified July 2009 - Conditions: Overweight; Obesity
Interventions: Behavioral: Exercise - Aerobic and Resistance; Behavioral: Dietary - Caloric Restriction
Sponsors: McMaster University; McMaster University; Dairy Farmers of Canada; Dairy Management Inc.; Hamilton Health Sciences Corporation
Completed - verified July 2011 - Condition: Breast Cancer
Intervention:
Sponsors: University Health Network, Toronto; University Health Network, Toronto; St. Michael's Hospital, Toronto
Not yet recruiting - verified November 2008 - Conditions: Cognition; Aging
Interventions: Drug: tamoxifen; Drug: raloxifene
Sponsors: Wake Forest University; Wake Forest University; National Institute on Aging (NIA)
Completed - verified May 2008 - Conditions: Acute Coronary Syndrome; Myocardial Infarction; Smoking
Interventions: Drug: Bupropion HCl ER; Drug: Placebo
Sponsors: McGill University; Mark Eisenberg; Canadian Institutes of Health Research (CIHR); Heart and Stroke Foundation of Quebec
Completed - verified May 2008 - Conditions: Respiratory Syncytial Virus (RSV); Parainfluenza Virus Type 3 (PIV3)
Interventions: Biological: MEDI-534; Biological: MEDI-534; Biological: MEDI-534; Biological: MEDI-534; Biological: MEDI-534; Biological: Placebo
Sponsors: MedImmune LLC; MedImmune LLC
Active, not recruiting - verified May 2012 - Condition: Overactive Bladder
Interventions: Drug: DR-3001; Drug: DR-3001; Drug: Placebo
Sponsors: Duramed Research; Duramed Research
Completed - verified August 2011 - Condition: Vasomotor Symptoms
Interventions: Drug: desvenlafaxine succinate (DVS) SR; Drug: Placebo
Sponsors: Pfizer; Pfizer
Completed - verified July 2011 - Condition: Cardiac Arrest
Intervention:
Sponsors: Ottawa Hospital Research Institute; Ottawa Hospital Research Institute; Heart and Stroke Foundation of Canada; Canadian Institutes of Health Research (CIHR)
Completed - verified March 2012 - Condition: Obesity
Interventions: Behavioral: UC (Usual Care Group); Behavioral: BI (Behavioral Intervention Group)
Sponsors: Queen's University; Queen's University; Canadian Institutes of Health Research (CIHR)
Completed - verified October 2008 - Conditions: Osteoarthritis; Arthroplasty; Hip Replacement
Interventions: Procedure: Motion analysis; Procedure: Motion analysis; Procedure: Motion analysis
Sponsors: Ottawa Hospital Research Institute; Ottawa Hospital Research Institute; Canadian Institutes of Health Research (CIHR)
Recruiting - verified December 2011 - Condition: Thalassemia
Intervention:
Sponsors: New England Research Institutes; New England Research Institutes; National Heart, Lung, and Blood Institute (NHLBI); Thalassemia Clinical Research Network
Completed - verified June 2011 - Condition: Healthy
Interventions: Device: repetitive transcranial magnetic stimulation (rTMS); Device: repetitive transcranial magnetic stimulation (rTMS); Device: sham repetitive transcranial magnetic stimulation (rTMS)
Sponsors: Centre for Addiction and Mental Health; Centre for Addiction and Mental Health
Recruiting - verified May 2012 - Condition: Asthma
Interventions: Drug: MEDI-563; Drug: MEDI-563; Other: Placebo Comp.; Other: Placebo
Sponsors: MedImmune LLC; MedImmune LLC
Completed - verified October 2011 - Conditions: Amnestic Mild Cognitive Impairment; Aging
Interventions: Behavioral: Recollection Training; Behavioral: Control
Sponsors: Baycrest; Baycrest
Recruiting - verified September 2011 - Condition: Hernia
Intervention:
Sponsors: Ethicon, Inc.; Ethicon, Inc.
Recruiting - verified April 2012 - Condition: Meningococcal Infections
Interventions: Biological: MenACWY-CRM; Biological: MenACWY-CRM; Biological: Licensed meningococcal ACWY vaccine
Sponsors: Novartis; Novartis Vaccines
Completed - verified December 2011 - Conditions: Influenza Disease Caused by an Influenza A Virus; Influenza Vaccines
Interventions: Biological: GSK 1557484A; Biological: Placebo
Sponsors: GlaxoSmithKline; GlaxoSmithKline
Completed - verified March 2011 - Condition: Glabellar Furrowing
Intervention: Device: GFX
Sponsors: Advanced Cosmetic Intervention; Advanced Cosmetic Intervention
Completed - verified April 2008 - Condition: Femoroacetabular, Impingement
Interventions: Procedure: Motion analysis; Procedure: Motion analysis
Sponsors: Ottawa Hospital Research Institute; Ottawa Hospital Research Institute
Active, not recruiting - verified December 2011 - Condition: Femoroacetabular Hip Impingement Syndrome
Intervention:
Sponsors: Ottawa Hospital Research Institute; Ottawa Hospital Research Institute
Active, not recruiting - verified October 2011 - Condition: Congestive Heart Failure
Intervention: Other: NT-proBNP guided care
Sponsors: St. Michael's Hospital, Toronto; St. Michael's Hospital, Toronto; Hoffmann-La Roche
Recruiting - verified July 2009 - Conditions: Deglutition Disorders; Dysphagia; Stroke
Intervention: Other: TOR-BSST© Refresher Training
Sponsors: University Health Network, Toronto; University Health Network, Toronto; Ontario Ministry of Health and Long Term Care
Completed - verified January 2012 - Condition: Coronary Heart Disease
Intervention: Behavioral: 12-week risk reduction program, managed by a Heart Health Educator
Sponsors: University of Ottawa Heart Institute; University of Ottawa Heart Institute; Heart and Stroke Foundation of Canada
Completed - verified December 2011 - Conditions: Accidental Falls; Musculoskeletal Equilibrium
Interventions: Procedure: computerized visual training; Procedure: computerized word puzzles; Procedure: video-game based visual training
Sponsors: Sunnybrook Health Sciences Centre; Sunnybrook Health Sciences Centre; Ontario Neurotrauma Foundation; Canadian Institutes of Health Research (CIHR)
Active, not recruiting - verified July 2011 - Condition: Gastric Acid
Interventions: Drug: Esomeprazole first; Drug: Generic omeprazole first
Sponsors: Queen's University; Queen's University; Canadian Institutes of Health Research (CIHR)
Recruiting - verified January 2012 - Condition: Influenza
Interventions: Drug: oseltamivir; Drug: oseltamivir; Other: Alternative Control
Sponsors: Hoffmann-La Roche; Hoffmann-La Roche
Recruiting - verified May 2012 - Condition: Contraception
Interventions: Drug: G04209F; Drug: G04209G
Sponsors: Bayer; Bayer
Active, not recruiting - verified April 2012 - Condition: Depression
Intervention: Drug: escitalopram
Sponsors: Centre for Addiction and Mental Health; Centre for Addiction and Mental Health; Queen's University
Recruiting - verified January 2012 - Conditions: Heart Disease; Diabetes; Hypertension
Interventions: Behavioral: No further instruction; Behavioral: Food Delivery; Behavioral: Fruits (F), vegetables (V), and whole grain (WG) counseling; Behavioral: Counseling to reduce soft drink intake.; Behavioral: Food Delivery & F, V & WG counseling.; Behavioral: Food delivery & soft drink counseling; Behavioral: F, V, WG & soft drink counseling; Behavioral: Food delivery and F,V, WG & soft drink counseling
Sponsors: University of Toronto; University of Toronto; St. Michael's Hospital, Toronto; Cancer Care Ontario
Completed - verified July 2011 - Conditions: Embolism; Femoral Fractures
Intervention: Device: Reamer Irrigator Aspirator
Sponsors: St. Michael's Hospital, Toronto; St. Michael's Hospital, Toronto; Orthopaedic Trauma Association; Synthes Inc.
Recruiting - verified July 2011 - Condition: Rotator Cuff Tear
Interventions: Procedure: single row; Procedure: double row fixation
Sponsors: Ottawa Hospital Research Institute; Ottawa Hospital Research Institute
Completed - verified September 2011 - Condition: Breast Cancer
Intervention:
Sponsors: University Health Network, Toronto; University Health Network, Toronto; Mount Sinai Hospital, Canada; Hamilton Health Sciences Corporation
Recruiting - verified November 2008 - Condition: Pulmonary Disease, Chronic Obstructive
Interventions: Drug: tiotropium; Drug: Placebo
Sponsors: Boehringer Ingelheim Pharmaceuticals; Boehringer Ingelheim Pharmaceuticals; Pfizer
Completed - verified November 2011 - Condition: Social Anxiety Disorder
Interventions: Drug: Cipralex; Drug: Placebo
Sponsors: START Clinic for Mood and Anxiety Disorders; START Clinic for Mood and Anxiety Disorders; H. Lundbeck A/S
Active, not recruiting - verified October 2008 - Conditions: Primary Open Angle Glaucoma; Pseudo-exfoliative Glaucoma
Interventions: Drug: prednisolone 1%; Drug: ketorolac 0.5%; Drug: methyl cellulose drops (artificial tears)
Sponsors: Queen's University; Queen's University; Pfizer; Glaucoma Research Society of Canada
Completed - verified October 2011 - Condition: Healthy
Intervention:
Sponsors: Sunnybrook Health Sciences Centre; Sunnybrook Health Sciences Centre
Completed - verified August 2011 - Condition: Dupuytren's Contracture
Intervention:
Sponsors: McMaster University; Hamilton Health Sciences Corporation; McMaster University
Completed - verified July 2011 - Condition: Labor Pain
Interventions: Procedure: Combined spinal epidural; Procedure: Tsui Test for intrathecal catheter
Sponsors: Samuel Lunenfeld Research Institute, Mount Sinai Hospital; Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Completed - verified September 2011 - Conditions: Acute Renal Failure; Gastroenteritis; Dehydration
Intervention:
Sponsors: Children's Hospital of Eastern Ontario; Children's Hospital of Eastern Ontario
Completed - verified September 2007 - Conditions: Depression; Sleep Apnea, Obstructive
Intervention: Device: continuous positive airway pressure (CPAP)
Sponsors: Queen's University; Queen's University
Recruiting - verified April 2012 - Condition: Progressive Supranuclear Palsy
Intervention:
Sponsors: University of Louisville; University of Louisville; National Institute on Aging (NIA)
Recruiting - verified December 2011 - Conditions: Rubella; Vaccine
Intervention:
Sponsors: St. Michael's Hospital, Toronto; St. Michael's Hospital, Toronto
Active, not recruiting - verified December 2009 - Condition: Cardiac Arrest
Intervention: Procedure: bystander CPR using 30:2 ratio vs 15:2 ratio
Sponsors: Ottawa Hospital Research Institute; Ottawa Hospital Research Institute
Completed - verified May 2012 - Condition: Osteoarthritis, Knee
Intervention: Device: DePuy P.F.C.® Sigma Rotating Platform Knee
Sponsors: Queen's University; Queen's University; DePuy Orthopaedics
Active, not recruiting - verified April 2012 - Condition: Heart Defects, Congenital
Interventions: Behavioral: Physical Activity; Behavioral: Education
Sponsors: The Hospital for Sick Children; The Hospital for Sick Children; Heart and Stroke Foundation of Ontario
Completed - verified August 2011 - Conditions: Hepatitis C; Pregnancy
Intervention:
Sponsors: St. Michael's Hospital, Toronto; St. Michael's Hospital, Toronto
Active, not recruiting - verified December 2009 - Condition: Prophylaxis for HPV Infections and Associated Cervical Neoplasia
Interventions: Biological: Cervarix; Biological: Placebo control
Sponsors: GlaxoSmithKline; GlaxoSmithKline
Active, not recruiting - verified February 2012 - Conditions: Pulmonary Disease, Chronic Obstructive; Chronic Obstructive Pulmonary Disease (COPD)
Intervention: Other: Novel endpoint determination
Sponsors: GlaxoSmithKline; GlaxoSmithKline
Completed - verified February 2012 - Conditions: Obesity; Diabetes
Interventions: Drug: Low fibre breakfast cereal (puffed rice/cornflakes); Drug: High fibre cereal (All Bran/Bran Flakes)
Sponsors: University of Toronto; University of Toronto; Canadian Diabetes Association; Canadian Institutes of Health Research (CIHR)
Completed - verified August 2007 - Condition: Respiratory Tract Infection
Interventions: Dietary Supplement: COLD-fX natural health product; Dietary Supplement: COLD-fX; Other: Placebo
Sponsors: Capital Health, Canada; Capital Health, Canada; Afexa Life Sciences Inc; IWK Health Centre; Sunnybrook Health Sciences Centre; Erasmus Medical Center; University of BC Gerontology & Diabetes Research
Completed - verified July 2011 - Condition: Herpes Simplex
Interventions: Biological: GSK208141; Biological: HavrixTM (investigational formulation); Biological: Placebo
Sponsors: GlaxoSmithKline; GlaxoSmithKline
Completed - verified April 2012 - Condition: Contraception
Intervention: Drug: EV/DNG (Qlaira, BAY86-5027, SH T00658ID)
Sponsors: Bayer; Bayer
Completed - verified August 2011 - Condition: Obesity
Intervention: Behavioral: aerobic and resistance exercise
Sponsors: Ottawa Hospital Research Institute; Ottawa Hospital Research Institute; Canadian Institutes of Health Research (CIHR); Canadian Diabetes Association
Completed - verified July 2011 - Conditions: Systemic Lupus Erythematosus; Antiphospholipid Syndrome
Intervention:
Sponsors: Hospital for Special Surgery, New York; Hospital for Special Surgery, New York; National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Recruiting - verified December 2011 - Conditions: HIV Infections; AIDS; Lactic Acidosis; Lipodystrophy
Intervention: Drug: cofactor supplementation (thiamine, riboflavin, L-carnitine)
Sponsors: Queen's University; Queen's University; Ontario HIV Treatment Network
Completed - verified October 2011 - Condition: Chronic Obstructive Pulmonary Disease
Intervention:
Sponsors: St. Joseph's Healthcare Hamilton; St. Joseph's Healthcare Hamilton
Recruiting - verified July 2011 - Condition: Toxemia
Intervention: Behavioral: preeclampsia
Sponsors: University of British Columbia; University of British Columbia
Recruiting - verified March 2012 - Conditions: Lung Cancer; Mesothelioma
Intervention:
Sponsors: University Health Network, Toronto; University Health Network, Toronto
Recruiting - verified January 2012 - Condition: Lung Cancer
Intervention:
Sponsors: University Health Network, Toronto; University Health Network, Toronto
Recruiting - verified February 2012 - Condition: Breast Cancer
Intervention:
Sponsors: University Health Network, Toronto; University Health Network, Toronto
Completed - verified August 2011 - Condition: Breast Cancer
Intervention:
Sponsors: University Health Network, Toronto; University Health Network, Toronto; Susan G. Komen Breast Cancer Foundation; Dr. Julia Knight (research collaborator)
Completed - verified October 2011 - Condition: Borderline Personality Disorder
Interventions: Behavioral: General Psychiatric Management; Behavioral: Dialectical Behaviour Therapy
Sponsors: Centre for Addiction and Mental Health; Centre for Addiction and Mental Health; Canadian Institutes of Health Research (CIHR); St. Michael's Hospital, Toronto
Active, not recruiting - verified September 2011 - Conditions: Post-Menopausal Osteoporosis; Post-Menopausal Osteopenia
Interventions: Dietary Supplement: vitamin K1 (phylloquinone); Dietary Supplement: placebo
Sponsors: University Health Network, Toronto; University Health Network, Toronto; Canadian Institutes of Health Research (CIHR)
Completed - verified January 2012 - Condition: Breast Hypertrophy
Intervention: Radiation: Vertical scar versus inferior pedicle reduction mammoplasty
Sponsors: McMaster University; McMaster University; Canadian Society of Plastic Surgeons
Completed - verified July 2011 - Conditions: Sleep Problems; Behavior Problems; Child Behavior
Interventions: Behavioral: Self-help treatment booklet and telephone support; Behavioral: Usual care by a family physician
Sponsors: University of Western Ontario, Canada; University of Western Ontario, Canada; Canadian Institutes of Health Research (CIHR); The Provincial Centre of Excellence for Child and Youth Mental Health at CHEO
Completed - verified August 2011 - Conditions: Hernia, Inguinal; Hydrocele
Intervention: Drug: clonidine
Sponsors: Children's Hospital of Eastern Ontario; Children's Hospital of Eastern Ontario
Recruiting - verified February 2012 - Conditions: Human Papillomavirus (HPV) Infection; Cervical Neoplasia
Interventions: Biological: Cervarix™; Biological: Havrix™-based investigational formulation
Sponsors: GlaxoSmithKline; GlaxoSmithKline
Completed - verified February 2012 - Condition: Papillomavirus Infection
Intervention: Biological: HPV 16/18 VLP AS04
Sponsors: GlaxoSmithKline; GlaxoSmithKline
Completed - verified October 2011 - Condition: Alzheimer's Disease
Interventions: Procedure: Magnetic Resonance Imaging (MRI); Procedure: Positron Emission Tomography (PET); Procedure: Lumbar Puncture (LP)
Sponsors: Alzheimer's Disease Cooperative Study (ADCS); Alzheimer's Disease Cooperative Study (ADCS); Northern California Institute for Research and Education (NCIRE); National Institute on Aging (NIA); National Institute for Biomedical Imaging and Bioengineering (NIBIB); Foundation for the National Institutes of Health; Alzheimer’s Drug Discovery Foundation; Alzheimer's Association
Completed - verified January 2012 - Conditions: Depressive Disorder, Major; Major Depressive Disorder (MDD)
Intervention: Drug: GW679769
Sponsors: GlaxoSmithKline; GlaxoSmithKline
Completed - verified February 2012 - Condition: Diabetes Mellitus, Type 1
Intervention:
Sponsors: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); National Center for Research Resources (NCRR); Juvenile Diabetes Research Foundation; American Diabetes Association
Recruiting - verified March 2012 - Condition: Breast Cancer
Intervention: Drug: exemestane
Sponsors: NCIC Clinical Trials Group; NCIC Clinical Trials Group; Grupo Espanol de Investigacion del Cancer de Mama; UNICANCER
Active, not recruiting - verified August 2011 - Conditions: Cystic Fibrosis; Diabetes Mellitus
Interventions: Drug: Insulin Asparte; Drug: Repaglinide
Sponsors: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Cystic Fibrosis Foundation; Novo Nordisk
Completed - verified February 2012 - Condition: Leukemia
Interventions: Drug: asparaginase; Drug: busulfan; Drug: cyclophosphamide; Drug: cyclosporine; Drug: cytarabine; Drug: daunorubicin hydrochloride; Drug: etoposide; Drug: gemtuzumab ozogamicin; Drug: methotrexate; Drug: mitoxantrone hydrochloride; Procedure: allogeneic bone marrow transplantation
Sponsors: National Cancer Institute (NCI); Children's Oncology Group; National Cancer Institute (NCI)
Completed - verified November 2010 - Condition: Leukemia
Interventions: Biological: filgrastim; Drug: asparaginase; Drug: cyclophosphamide; Drug: cyclosporine; Drug: cytarabine; Drug: daunorubicin hydrochloride; Drug: dexamethasone; Drug: etoposide; Drug: ifosfamide; Drug: imatinib mesylate; Drug: leucovorin calcium; Drug: mercaptopurine; Drug: methotrexate; Drug: pegaspargase; Drug: vincristine sulfate; Procedure: allogeneic bone marrow transplantation; Procedure: peripheral blood stem cell transplantation; Procedure: umbilical cord blood transplantation; Radiation: radiation therapy
Sponsors: National Cancer Institute (NCI); Children's Oncology Group; National Cancer Institute (NCI)
Completed - verified November 2010
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