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  • Validation of a Clinical Prediction Rule to Identify Patients With Shoulder Pain Likely to Benefit From Cervicothoracic Manipulation: A Randomized Clinical Trial

    Condition:   Shoulder Pain
    Interventions:   Procedure: Cervicothoracic Manipulation;   Procedure: Exercise
    Sponsors:   University of Colorado, Denver;   University of Colorado, Denver;   Virginia Commonwealth University;   University of Colorado, Boulder;   Northern Navajo Medical Center;   Gundersen Lutheran Health System;   Waldron’s Peak Physical Therapy;   Temple University
    Not yet recruiting - verified April 2012
  • Comparative Effectiveness of Early Physical Therapy Versus Usual Care for Low Back Pain

    Condition:   Low Back Pain
    Interventions:   Procedure: Usual Care;   Procedure: Early Physical Therapy
    Sponsors:   Madigan Army Medical Center;   Madigan Army Medical Center;   U.S. Army Medical Research and Materiel Command
    Recruiting - verified March 2012
  • Placebo Controlled Trial of Dextromethorphan in Rett Syndrome

    Condition:   Rett Syndrome
    Interventions:   Drug: dextromethorphan;   Drug: placebo
    Sponsors:   FDA Office of Orphan Products Development;   FDA Office of Orphan Products Development
    Not yet recruiting - verified January 2012
  • Clinical Benefits of a Novel Sleep-focused Mind-body Program on Gulf War Illness (GWI) Symptoms

    Conditions:   Sleep Disturbance;   Persian Gulf War Syndrome in Veteran
    Interventions:   Behavioral: Mind-Body Bridging Program;   Behavioral: Supportive Education
    Sponsors:   University of Utah;   University of Utah;   VA Salt Lake City Health Care System;   Department of Defense
    Recruiting - verified March 2012
  • Behavioral Therapy to Treat Urinary Symptoms in Parkinson Disease

    Conditions:   Urinary Incontinence;   Nocturia
    Interventions:   Behavioral: Exercise-based behavioral therapy;   Behavioral: Behavioral control
    Sponsors:   Atlanta VA Medical Center;   Atlanta VA Medical Center
    Not yet recruiting - verified January 2012
  • Vitamin D Status, Disease Specific and Quality of Life Outcomes in Patients With Cutaneous Lupus

    Condition:   Cutaneous Lupus Erythematosus
    Intervention:   Dietary Supplement: vitamin D
    Sponsors:   Emory University;   Emory University;   Dermatology Foundation
    Recruiting - verified January 2012
  • Amino Acid Supplementation in Recovery From Traumatic Brain Injury

    Condition:   Traumatic Brain Injury
    Interventions:   Dietary Supplement: Amino Acids;   Dietary Supplement: Placebo of inert compounds;   Dietary Supplement: Valine
    Sponsors:   The University of Texas, Galveston;   The University of Texas, Galveston;   The Moody Foundation
    Recruiting - verified February 2012
  • Delivery of Self Training and Education for Stressful Situations-Telephone Version

    Condition:   PTSD
    Interventions:   Behavioral: DESTRESS-T;   Other: Optimized Usual Care (OUC)
    Sponsors:   Uniformed Services University of the Health Sciences;   Uniformed Services University of the Health Sciences;   Walter Reed National Military Medical Center;   Department of Defense;   Department of Veterans Affairs
    Not yet recruiting - verified January 2012
  • New Therapy for Patients With Severe Tinnitus

    Condition:   Tinnitus
    Interventions:   Other: Sound Based and Educational Therapies;   Other: Integrated Medicine Therapies and Sound Based Education Therapies;   Other: Integrated Medicine Therapies and SBE
    Sponsors:   Duke University;   Duke University;   National Institutes of Health (NIH);   National Institute on Deafness and Other Communication Disorders (NIDCD)
    Recruiting - verified November 2011
  • Exercise Trial in Chronic Kidney Disease

    Condition:   Chronic Kidney Disease
    Interventions:   Behavioral: Aerobic exercise training;   Behavioral: Health Education
    Sponsors:   University of Maryland;   University of Maryland;   National Institutes of Health (NIH);   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
    Recruiting - verified March 2012
  • Asenapine in the Treatment of Older Adults With Bipolar Disorder

    Condition:   Bipolar Disorder
    Intervention:   Drug: Asenapine
    Sponsors:   University Hospitals of Cleveland;   University Hospitals of Cleveland;   Case Western Reserve University
    Recruiting - verified May 2012
  • N-methyl-D-aspartic Acid (NMDA) and Cognitive Remediation in Schizophrenia

    Conditions:   Schizophrenia;   Schizoaffective Disorder
    Interventions:   Drug: D-serine;   Drug: placebo;   Behavioral: Sensory Based remediation paradigm
    Sponsors:   Nathan Kline Institute for Psychiatric Research;   Nathan Kline Institute for Psychiatric Research;   Columbia University
    Not yet recruiting - verified July 2011
  • Socialization of Adult Men With Congenital Hemophilia A or B

    Conditions:   Hemophilia A;   Hemophilia B
    Intervention:  
    Sponsors:   Dana-Farber Cancer Institute;   Dana-Farber Cancer Institute;   Brigham and Women's Hospital
    Recruiting - verified January 2012
  • Patient and Provider Interventions for Managing Osteoarthritis in Primary Care

    Condition:   Osteoarthritis
    Interventions:   Behavioral: Patient Behavioral Intervention for OA;   Behavioral: Provider Intervention for OA;   Behavioral: Combined Patient and Provider Interventions for OA
    Sponsors:   Duke University;   Duke University;   National Institutes of Health (NIH);   National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
    Recruiting - verified September 2011
  • Physical and Cognitive Function - Look AHEAD Ancillary Study

    Conditions:   Diabetes;   Weight Loss;   Physical Function;   Cognitive Function
    Interventions:   Behavioral: Lifestyle intervention;   Behavioral: Diabetes Support Education
    Sponsors:   Wake Forest University;   Wake Forest University;   Pennington Biomedical Research Center;   University of Colorado, Denver;   University of Tennessee;   University of Pittsburgh
    Recruiting - verified September 2011
  • Stroke Health and Risk Education (SHARE)

    Conditions:   Stroke;   Hypertension
    Interventions:   Behavioral: Educational intervention for diet and physical activity;   Behavioral: Educational message on skin cancer awareness
    Sponsors:   University of Michigan;   University of Michigan;   National Institute of Neurological Disorders and Stroke (NINDS);   Diocese of Corpus Christi, Texas, USA
    Recruiting - verified June 2011
  • A Modified Rehabilitation Intervention for Working Persons With Arthritis

    Condition:   Arthritis
    Intervention:   Behavioral: Vocational Rehabilitation Intervention
    Sponsors:   Boston University;   Boston University;   U.S. Department of Education
    Recruiting - verified July 2011
  • Neuroactive Steroids and Traumatic Brain Injury (TBI) in OEF/OIF Veterans

    Condition:   Brain Injuries, Traumatic
    Interventions:   Drug: Pregnenolone;   Drug: Placebo
    Sponsors:   Department of Veterans Affairs;   Department of Veterans Affairs
    Not yet recruiting - verified April 2012
  • Collaborative Care for Older Adults With Back Pain (COCOA)

    Condition:   Low Back Pain
    Interventions:   Other: Medical Care;   Other: Dual Care;   Other: Shared Care
    Sponsors:   Palmer College of Chiropractic;   Palmer College of Chiropractic;   Health Resources and Services Administration (HRSA);   Genesis Family Medical Center;   University of Iowa;   Thomas Jefferson University
    Recruiting - verified January 2012
  • Efficacy and Safety of Flexibly Dosed BMS-820836 in the Treatment of Patients With Treatment Resistant Major Depression

    Condition:   Depression
    Interventions:   Drug: Duloxetine;   Drug: Placebo matching with BMS-820836;   Drug: BMS-820836;   Drug: Duloxetine;   Drug: Placebo matching with Duloxetine
    Sponsors:   Bristol-Myers Squibb;   Bristol-Myers Squibb
    Recruiting - verified February 2012
  • Social Cognition Intervention

    Condition:   Psychosis
    Interventions:   Behavioral: social cognitive training with in vivo augmentation;   Behavioral: social cognitive training;   Behavioral: non-social skills training
    Sponsors:   Department of Veterans Affairs;   Department of Veterans Affairs
    Recruiting - verified April 2012
  • Care Management for the Effective Use of Opioids

    Conditions:   Low Back Pain;   Pain
    Interventions:   Drug: Analgesic and co-analgesic therapy;   Behavioral: Pain self-management/coping skills treatment
    Sponsors:   Department of Veterans Affairs;   Department of Veterans Affairs
    Recruiting - verified February 2012
  • Reducing Risk After an Adverse Pregnancy Outcome

    Condition:   Maternal Depression
    Intervention:   Behavioral: Project Solve Education
    Sponsors:   Boston Medical Center;   Boston Medical Center
    Recruiting - verified June 2011
  • Acute Neurobehavioral Program for Improving Functional Status After TBI

    Condition:   Traumatic Brain Injury
    Interventions:   Behavioral: FANCI;   Behavioral: FANCI
    Sponsors:   Virginia Commonwealth University;   Virginia Commonwealth University;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
    Recruiting - verified March 2012
  • Caregiver Stress: Interventions to Promote Health and Wellbeing

    Condition:   Health Promotion
    Interventions:   Behavioral: Usual Care;   Behavioral: Psycho-education;   Behavioral: Psycho-education plus physical exercise
    Sponsors:   Emory University;   Emory University;   National Institute of Nursing Research (NINR)
    Recruiting - verified May 2012
  • Interventions for Children With Attention and Reading Disorders

    Conditions:   Attention Deficit Hyperactivity Disorder;   Reading Difficulty or Disability
    Interventions:   Drug: Methylphenidate;   Behavioral: Intensive reading instruction;   Behavioral: Parent Training;   Drug: Mixed Salt Amphetamine;   Drug: Atomoxetine;   Drug: Guanfacine
    Sponsors:   The University of Texas Health Science Center, Houston;   The University of Texas Health Science Center, Houston;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
    Recruiting - verified February 2012
  • Patient and Provider Interventions for Managing Osteoarthritis in Primary Care

    Condition:   Osteoarthritis
    Intervention:   Behavioral: Osteoarthritis Intervention
    Sponsors:   Department of Veterans Affairs;   Department of Veterans Affairs
    Recruiting - verified March 2012
  • Chiropractic and Exercise for Low Back Pain in Adolescents

    Condition:   Low Back Pain
    Interventions:   Other: Chiropractic + Exercise;   Other: Exercise
    Sponsors:   Northwestern Health Sciences University;   Northwestern Health Sciences University;   Health Resources and Services Administration (HRSA);   University of Western States
    Recruiting - verified June 2011
  • Safety and Feasibility of Minocycline in the Treatment of Traumatic Brain Injury (TBI)

    Condition:   Traumatic Brain Injury
    Intervention:   Drug: Minocycline
    Sponsors:   Wayne State University;   Wayne State University
    Recruiting - verified January 2012
  • Progesterone for the Management of Preterm, Premature Rupture of the Membranes: A Randomized Controlled Trial.

    Condition:   Pregnancy Complications
    Intervention:   Drug: 17-Hydroxyprogesterone Caproate vs Castor oil (placebo)
    Sponsors:   Stanford University;   Stanford University
    Recruiting - verified April 2012
  • Hearing Loss Prevention for Veterans

    Condition:   Hearing Loss, Noise-Induced
    Interventions:   Behavioral: Multimedia hearing loss prevention program;   Behavioral: Hearing Conservation brochure
    Sponsors:   Department of Veterans Affairs;   Department of Veterans Affairs
    Recruiting - verified February 2012
  • Supporting the Well Being of Families of Young Children With Autism Spectrum Disorders

    Condition:   Maternal Depression
    Intervention:   Behavioral: Problem Solving Education
    Sponsors:   Boston Medical Center;   Boston Medical Center;   HRSA/Maternal and Child Health Bureau
    Recruiting - verified June 2011
  • Defining the Anti-inflammatory Role of Lipoic Acid in Multiple Sclerosis

    Condition:   Multiple Sclerosis
    Intervention:   Dietary Supplement: Lipoic Acid
    Sponsors:   Portland VA Medical Center;   Portland VA Medical Center;   Oregon Health and Science University
    Recruiting - verified January 2012
  • Cholesterol in ASD: Characterization and Treatment

    Conditions:   Autism;   Asperger Disorder;   PDD-NOS
    Intervention:   Other: Cholesterol
    Sponsors:   National Institutes of Health Clinical Center (CC);   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
    Recruiting - verified April 2012
  • Ecosystem Focused Therapy for Treating Older Depressed Stroke Survivors

    Conditions:   Ischemic Stroke;   Depression
    Interventions:   Behavioral: Ecosystem Focused Therapy (EFT);   Behavioral: Education in stroke and depression
    Sponsors:   Weill Medical College of Cornell University;   Weill Medical College of Cornell University;   National Institute of Mental Health (NIMH)
    Recruiting - verified February 2012
  • Spinal Cord Stimulator Implant Study

    Condition:   Back Pain
    Interventions:   Behavioral: Coping Skills Training;   Behavioral: Education
    Sponsors:   Duke University;   Duke University
    Recruiting - verified May 2012
  • Arm Rehabilitation Study After Stroke

    Conditions:   Stroke;   Brain Infarction;   Brain Ischemia;   Cerebral Infarction;   Cerebrovascular Disorders
    Interventions:   Behavioral: Accelerated Skill Acquisition Program (ASAP);   Behavioral: Dose-Equivalent Usual & Customary Care - DEUCC;   Behavioral: Usual and Customary Care - UCC
    Sponsors:   University of Southern California;   University of Southern California;   National Institute of Neurological Disorders and Stroke (NINDS);   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
    Recruiting - verified August 2011
  • Life Improvement Following Traumatic Brain Injury

    Conditions:   Traumatic Brain Injury;   Depression
    Interventions:   Behavioral: In-person Cognitive Behavioral Therapy;   Behavioral: Telephone Cognitive Behavioral Therapy
    Sponsors:   University of Washington;   University of Washington;   National Institutes of Health (NIH);   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);   U.S. Department of Education
    Recruiting - verified January 2012
  • Magnetic Resonance Imaging (MRI) and Neurodevelopmental Outcomes in Preterm Infants Following Administration of High-Dose Caffeine

    Conditions:   Apnea of Prematurity;   Intraventricular Hemorrhage;   White Matter Injury
    Intervention:   Drug: Caffeine citrate
    Sponsors:   Washington University School of Medicine;   Washington University School of Medicine
    Recruiting - verified August 2011
  • Diffusion Tensor Imaging (DTI) in Infants With Krabbe Disease

    Condition:   Krabbe Disease
    Intervention:  
    Sponsors:   University of Pittsburgh;   University of Pittsburgh;   New York State Department of Health;   Hunter's Hope
    Recruiting - verified January 2012
  • Physiological Disturbances Associated With Neonatal Intraventricular Hemorrhage

    Conditions:   Intraventricular Hemorrhage;   Autoregulation
    Interventions:   Device: Hypercapnia;   Other: Normocapnia
    Sponsors:   University of Arkansas;   University of Arkansas;   National Institute of Neurological Disorders and Stroke (NINDS)
    Recruiting - verified January 2012
  • Cannabis for Spasticity in Multiple Sclerosis

    Condition:   Multiple Sclerosis
    Interventions:   Drug: Smoked Cannabis;   Drug: Smoked Cannabis and oral marinol;   Drug: Placebo
    Sponsors:   University of California, Davis;   University of California, Davis;   National Multiple Sclerosis Society
    Recruiting - verified March 2012
  • Neurobiology and Treatment of Reading Disability in NF-1

    Conditions:   Neurofibromatosis Type 1;   Reading Disabilities
    Interventions:   Behavioral: Tutoring Program I;   Behavioral: Tutoring Program II
    Sponsors:   Vanderbilt University;   Vanderbilt University;   National Institute of Neurological Disorders and Stroke (NINDS)
    Recruiting - verified June 2011
  • Efficacy of a Post-Rehabilitation Exercise Intervention

    Conditions:   Hip Fracture;   Disability
    Interventions:   Behavioral: Enhanced Strong for Life;   Behavioral: cardiovascular nutrition education
    Sponsors:   Boston University;   Boston University;   National Institute of Nursing Research (NINR);   Spaulding Rehabilitation Hospital
    Recruiting - verified June 2011
  • Treatment of Older Veterans With Chronic Posttraumatic Stress Disorder

    Conditions:   Combat Disorders;   Post-traumatic Stress Disorder
    Interventions:   Behavioral: Prolonged Exposure Therapy (PE);   Behavioral: Relaxation Training (RT)
    Sponsors:   Department of Veterans Affairs;   Department of Veterans Affairs
    Recruiting - verified January 2012
  • Study of the Safety and Effectiveness of DIAM™ Spinal Stabilization System Versus Conservative Care

    Condition:   Lumbar Degenerative Disc Disease
    Interventions:   Device: DIAM™ Spinal Stabilization System;   Procedure: Conservative care
    Sponsors:   Medtronic Spinal and Biologics;   Medtronic Spinal and Biologics
    Recruiting - verified March 2012
  • An Assessment of P-15 Bone Putty in Anterior Cervical Fusion With Instrumentation

    Condition:   Cervical Degenerative Disc Disease (DDD)
    Interventions:   Device: P-15 Synthetic osteoconductive bone substitute;   Other: Autologous bone
    Sponsors:   AO Clinical Investigation and Documentation;   AO Clinical Investigation and Documentation;   CeraPedics, Inc
    Recruiting - verified October 2011
  • Long-term Observation of Patients With Early Rheumatoid Arthritis

    Condition:   Rheumatoid Arthritis
    Intervention:  
    Sponsors:   University of California, Los Angeles;   University of California, Los Angeles
    Recruiting - verified August 2011
  • Studies of the Natural History and Pathogenesis and Outcome of Neonatal Onset Multisystem Inflammatory Disease (NOMID/CAPS, DIRA, CRMO, Still's Disease, Behcet's Disease, and Other Undifferentiated Autoinflammatory Diseases)

    Conditions:   Urticaria;   Arthropathy;   Lymphadenopathy;   Nervous System Anomalies
    Intervention:  
    Sponsors:   National Institutes of Health Clinical Center (CC);   National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
    Recruiting - verified January 2012
  • Adult and Juvenile Myositis

    Conditions:   Dermatomyositis;   Polymyositis;   Idiopathic Inflammatory Myopathy;   Healthy
    Intervention:  
    Sponsors:   National Institutes of Health Clinical Center (CC);   National Institute of Environmental Health Sciences (NIEHS)
    Recruiting - verified September 2011
  • Hereditary Deficits in Auditory Processing Leading to Language Impairment

    Conditions:   Auditory Perceptual Disorder;   Language Delay;   Language Disorder
    Intervention:  
    Sponsors:   National Institutes of Health Clinical Center (CC);   National Institute on Deafness and Other Communication Disorders (NIDCD)
    Recruiting - verified December 2011

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