- Condition: Major Depressive Disorder
Intervention: Behavioral: Internet Cognitive Behavioral Therapy
Sponsors: Mclean Hospital; Mclean Hospital
Not yet recruiting - verified May 2012 - Condition: Treatment-Resistant Depression
Intervention:
Sponsors: Mclean Hospital; Mclean Hospital; Pfizer; Massachusetts General Hospital
Not yet recruiting - verified May 2012 - Conditions: Obsessive Compulsive Disorder; Major Depressive Disorder
Intervention: Device: Medtronic IPG Neurostimulator
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Not yet recruiting - verified May 2012 - Condition: Major Depressive Disorder
Interventions: Behavioral: Telephonic CBT; Behavioral: Wait List Control
Sponsors: Veritas Health Solutions LLC; Veritas Health Solutions LLC; Woburn Pediatric Associates; University of Connecticut Health Center
Recruiting - verified May 2012 - Condition: Major Depressive Disorder
Intervention: Drug: Ketamine
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified April 2012 - Condition: Major Depressive Disorder
Intervention:
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; ElMindA Ltd
Recruiting - verified April 2012 - Condition: Major Depressive Disorder
Interventions: Drug: Placebo; Drug: Vilazodone; Drug: Vilazodone
Sponsors: Forest Laboratories; Forest Laboratories
Recruiting - verified April 2012 - Conditions: Bipolar Disorder; Major Depressive Disorder
Intervention:
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; National Institute of Mental Health (NIMH)
Recruiting - verified April 2012 - Condition: Bipolar Depression
Intervention: Device: Deep TMS (H-Coil)
Sponsors: Brainsway; Brainsway
Not yet recruiting - verified May 2012 - Condition: Depressive Disorder, Major
Interventions: Drug: LuAA21004; Drug: Duloxetine; Drug: Placebo
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Global Research & Development Center, Inc.
Recruiting - verified May 2012 - Condition: Mild Cognitive Impairment
Intervention:
Sponsors: Pamlab, L.L.C.; Pamlab, L.L.C.; Clionsky Neuro Systems, Inc.
Recruiting - verified May 2012 - Conditions: Bipolar Depression; Unipolar Depression
Intervention: Device: Low Field Magnetic Stimulation Device
Sponsors: Mclean Hospital; Mclean Hospital
Recruiting - verified March 2012 - Conditions: MDD; Citalopram; Major Depressive Disorder
Intervention: Drug: citalopram
Sponsors: Mclean Hospital; Mclean Hospital
Recruiting - verified April 2012 - Condition: Bipolar Disorder
Intervention: Other: No interventions will be used
Sponsors: Mclean Hospital; Mclean Hospital
Recruiting - verified March 2012 - Condition: Major Depressive Disorder
Intervention: Device: Near-infrared radiation treatment via TLT (NeuroThera)
Sponsors: Massachusetts General Hospital; Paolo Cassano; PhotoThera, Inc; Mclean Hospital; North Suffolk Mental Health Association
Recruiting - verified April 2012 - Condition: Treatment Resistant Depression
Intervention: Genetic: Genotyping assays
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified March 2012 - Conditions: Obesessive Compulsive Disorder; Major Depressive Disorder
Intervention:
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Not yet recruiting - verified January 2012 - Conditions: Chronic Low Back Pain; Degenerative Disc Disease; Depression; Anxiety
Interventions: Drug: Oxycodone; Drug: Morphine
Sponsors: Brigham and Women's Hospital; Brigham and Women's Hospital; Arthritis Foundation; National Institute on Drug Abuse (NIDA)
Recruiting - verified March 2012 - Condition: Major Depressive Disorder
Interventions: Drug: ALKS 5461; Drug: Placebo
Sponsors: Alkermes; Alkermes
Recruiting - verified April 2012 - Condition: Major Depressive Disorder
Interventions: Drug: Placebo; Drug: Vilazodone; Drug: Vilazodone; Drug: Citalopram
Sponsors: Forest Laboratories; Forest Laboratories
Recruiting - verified March 2012 - Conditions: Major Depressive Disorder; Dysthymic Disorder; Depressive Disorder NOS; Chronic Pain
Intervention: Behavioral: Mindfulness Based Cognitive Therapy
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified April 2012 - Condition: Major Depressive Disorder
Interventions: Drug: Iloperidone; Drug: Placebo
Sponsors: Massachusetts General Hospital; Maurizio Fava, MD; Novartis Pharmaceuticals
Recruiting - verified April 2012 - Conditions: Anxiety Disorders; Depressive Disorders; Disruptive Behavior Disorders
Intervention: Behavioral: Behavioral and Affective Skills in Coping (BASIC)
Sponsors: Judge Baker Children's Center; Judge Baker Children's Center
Recruiting - verified November 2011 - Condition: Depression Disorder, Major
Interventions: Drug: RO4995819; Drug: RO4995819; Drug: RO4995819; Drug: Placebo
Sponsors: Hoffmann-La Roche; Hoffmann-La Roche
Recruiting - verified May 2012 - Condition: Seasonal Affective Disorder
Intervention: Device: goLITE
Sponsors: Philips Respironics; Philips Respironics
Recruiting - verified January 2012 - Condition: Major Depressive Disorder
Interventions: Drug: Amphetamine-dextroamphetamine (AMPH); Drug: Placebo; Behavioral: Well-being therapy
Sponsors: Massachusetts General Hospital; David P. Soskin,M.D.; Harvard University
Recruiting - verified March 2012 - Conditions: Suicidal Ideation; Major Depressive Disorder
Interventions: Behavioral: Dialectical Behavior Therapy Skills (DBT-S) Groups; Behavioral: Wait List-Treatment as Usual; Behavioral: No intervention-treatment as usual
Sponsors: Massachusetts General Hospital; Maurizio Fava, MD
Recruiting - verified April 2012 - Condition: Major Depressive Disorder
Interventions: Drug: SPD489 (Lisdexamfetamine dimesylate ); Drug: Placebo
Sponsors: Shire Development LLC; Shire Development LLC
Recruiting - verified May 2012 - Condition: Fibromyalgia
Interventions: Drug: Pregabalin; Drug: placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Condition: Major Depressive Disorder
Interventions: Drug: tasimelteon; Drug: placebo
Sponsors: Vanda Pharmaceuticals; Vanda Pharmaceuticals
Recruiting - verified May 2012 - Condition: Psychotic Depression
Interventions: Drug: Olanzapine; Drug: Placebo
Sponsors: Weill Medical College of Cornell University; Weill Medical College of Cornell University; University of Toronto; University of Massachusetts, Worcester; University of Pittsburgh
Recruiting - verified March 2012 - Condition: Major Depressive Disorder
Intervention: Drug: Lurasidone
Sponsors: Sunovion; Sunovion
Recruiting - verified April 2012 - Condition: Major Depressive Disorder
Intervention: Drug: Escitalopram
Sponsors: Wyss Institute at Harvard University; Wyss Institute at Harvard University; Massachusetts General Hospital; Martinos Center for Biomedical Imaging; Massachusetts Institute of Technology
Recruiting - verified April 2012 - Condition: Major Depressive Disorder With Mixed Features
Interventions: Drug: Lurasidone; Drug: Placebo
Sponsors: Sunovion; Sunovion
Recruiting - verified April 2012 - Condition: Depression
Interventions: Drug: Sertraline; Drug: Placebo; Drug: BupropionXL
Sponsors: University of Texas Southwestern Medical Center; University of Texas Southwestern Medical Center
Recruiting - verified April 2012 - Condition: Geriatric Bipolar Depression
Intervention: Drug: Coenzyme Q10
Sponsors: Mclean Hospital; Mclean Hospital; National Institute of Mental Health (NIMH)
Recruiting - verified April 2012 - Condition: Pediatric Bipolar Spectrum Disorders
Interventions: Drug: Omega-3; Drug: Inositol
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified February 2012 - Condition: Depression
Interventions: Drug: Duloxetine; Drug: Escitalopram; Drug: BMS-820836 Placebo; Drug: BMS-820836; Drug: BMS-820836; Drug: BMS-820836; Drug: BMS-820836
Sponsors: Bristol-Myers Squibb; Bristol-Myers Squibb
Recruiting - verified August 2011 - Condition: Treatment Outcome
Interventions: Drug: Lu AA21004; Drug: Escitalopram
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Global Research & Development Center, Inc.
Recruiting - verified May 2012 - Condition: Depression
Interventions: Drug: Placebo matching with BMS-820836; Drug: BMS-820836; Drug: BMS-820836; Drug: BMS-820836
Sponsors: Bristol-Myers Squibb; Bristol-Myers Squibb
Recruiting - verified July 2011 - Conditions: Depressive Disorder; Depression; Depressive Disorder, Major; Mood Disorders; Mental Disorders
Interventions: Drug: OPC-34712 + ADT; Drug: Placebo + ADT; Drug: Placebo + ADT
Sponsors: Otsuka Pharmaceutical Development & Commercialization, Inc.; Otsuka Pharmaceutical Development & Commercialization, Inc.
Recruiting - verified July 2011 - Condition: Major Depressive Disorder
Interventions: Device: Cranial Electrical Stimulation via FW-100 Fisher Wallace Cranial Stimulator; Device: CES Sham via FW-100 Fisher Wallace Cranial Stimulator
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; Fisher Wallace Labs, LLC
Recruiting - verified April 2012 - Condition: Depression
Interventions: Drug: Armodafinil; Drug: Placebo
Sponsors: Teva Pharmaceutical Industries; Cephalon
Recruiting - verified May 2012 - Condition: Depression
Intervention: Behavioral: Problem Solving Education and Activated Referral to Care
Sponsors: Boston Medical Center; Boston Medical Center; Head Start and Early Head Start Programs in Action for Boston Community Development Incorporated
Recruiting - verified February 2012 - Conditions: Depression; Unipolar Depression; Treatment Resistant Depression
Intervention: Behavioral: Medication
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Mental Health (NIMH)
Not yet recruiting - verified November 2011 - Condition: Major Depressive Disorder
Interventions: Drug: LY2216684; Drug: Placebo
Sponsors: Eli Lilly and Company; Eli Lilly and Company
Recruiting - verified May 2012 - Conditions: Major Depressive Disorder; Major Depressive Disorder w/ Psychotic Features; Metabolic Syndrome
Intervention:
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; National Alliance for Research on Schizophrenia and Depression
Recruiting - verified April 2012 - Condition: Major Depressive Disorder
Intervention: Drug: ketamine
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified April 2012 - Condition: Major Depressive Disorder (MDD)
Interventions: Drug: Amisulpride; Drug: Placebo
Sponsors: Mclean Hospital; Mclean Hospital; National Institute of Mental Health (NIMH)
Recruiting - verified March 2012 - Condition: Treatment Resistant Depression
Interventions: Drug: CX157; Drug: Placebo
Sponsors: CeNeRx BioPharma Inc.; CeNeRx BioPharma Inc.
Recruiting - verified October 2011 - Conditions: Anxiety Disorders; Mood Disorders
Interventions: Behavioral: Single Diagnosis Treatment Protocol; Behavioral: Unified Protocol (UP)
Sponsors: Boston University; Boston University; National Institute of Mental Health (NIMH)
Recruiting - verified March 2012 - Condition: Depression
Interventions: Drug: Riluzole; Drug: placebo
Sponsors: Yale University; Yale University
Recruiting - verified March 2012 - Conditions: Depression; Generalized Anxiety Disorder; Panic Disorder
Interventions: Other: Collaborative care; Other: Usual care
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; American Heart Association
Recruiting - verified April 2012 - Condition: Depression
Intervention: Device: Transcranial Magnetic Stimulation (TMS)
Sponsors: Boston University; Boston University; Boston Medical Center
Not yet recruiting - verified June 2011 - Condition: Bipolar I Disorder
Intervention: Behavioral: Enhancing Emotion Regulation
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified April 2012 - Condition: Major Depressive Disorder (MDD)
Interventions: Drug: LY2216684; Drug: Placebo
Sponsors: Eli Lilly and Company; Eli Lilly and Company
Recruiting - verified May 2012 - Condition: Major Depressive Disorder
Interventions: Drug: LY2216684; Drug: Placebo
Sponsors: Eli Lilly and Company; Eli Lilly and Company
Recruiting - verified May 2012 - Condition: Maternal Depression
Intervention: Behavioral: Project Solve Education
Sponsors: Boston Medical Center; Boston Medical Center
Recruiting - verified June 2011 - Conditions: Depression; Bipolar
Interventions: Drug: ziprasidone; Drug: Sugar pill
Sponsors: Tufts Medical Center; Tufts Medical Center; Duke University; University of South Carolina
Recruiting - verified July 2011 - Condition: Depression
Interventions: Behavioral: Family Focused Treatment (FFT); Behavioral: Individual Treatment (IP)
Sponsors: Boston University; Boston University; University of California, Los Angeles; National Institute of Mental Health (NIMH)
Recruiting - verified June 2011 - Condition: Major Depressive Disorder
Intervention: Drug: Lisdexamfetamine Dimesylate 20-50 mg
Sponsors: Mclean Hospital; Mclean Hospital; Shire Development LLC
Recruiting - verified March 2012 - Condition: Spinal Cord Injuries
Intervention: Behavioral: Vocational Rehabilitation
Sponsors: Department of Veterans Affairs; Department of Veterans Affairs
Recruiting - verified May 2012 - Conditions: Anorexia Nervosa; Eating Disorder; Anxiety; Depression
Interventions: Drug: Testosterone; Drug: Placebo
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; National Institute of Mental Health (NIMH)
Recruiting - verified April 2012 - Condition: Depression
Intervention: Drug: Armodafinil
Sponsors: Teva Pharmaceutical Industries; Cephalon
Recruiting - verified May 2012 - Condition: Depression
Intervention: Drug: Scopolamine
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified April 2012 - Conditions: Parkinson's Disease; Depression
Intervention: Device: Repetitive transcranial magnetic stimulation (rTMS)
Sponsors: Beth Israel Deaconess Medical Center; Beth Israel Deaconess Medical Center; University of California, Los Angeles; University of Florida; University Health Network, Toronto; The Cleveland Clinic; Michael J. Fox Foundation for Parkinson's Research
Recruiting - verified January 2012 - Conditions: Obsessive Compulsive Disorder; Body Dysmorphic Disorder; Tourette Syndrome; Trichotillomania; Panic Disorder; Social Phobia; Generalized Anxiety Disorder; Depression; Post-Traumatic Stress Disorder; Attention Deficit Hyperactivity Disorder; Eating Disorder; Specific Phobia; General Medical Condition
Intervention: Behavioral: Cognitive behavioral therapy (CBT)
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified March 2012 - Condition: Depression
Interventions: Drug: Armodafinil; Drug: Armodafinil; Drug: Placebo
Sponsors: Teva Pharmaceutical Industries; Cephalon
Recruiting - verified May 2012 - Conditions: Schizophrenia; Schizophreniform Disorder
Interventions: Drug: Citalopram; Behavioral: Psychoeducation; Behavioral: Cognitive Behavioral Therapy (CBT); Radiation: Functional Magnetic Resonance Imaging (fMRI); Drug: Placebo; Behavioral: Psychoeducation; Behavioral: Cognitive Behavioral Therapy (CBT); Radiation: Functional Magnetic Resonance Imaging (fMRI)
Sponsors: National Institute of Mental Health (NIMH); National Institute of Mental Health (NIMH)
Recruiting - verified December 2011 - Condition: Maternal Depression
Intervention: Behavioral: Problem Solving Education
Sponsors: Boston Medical Center; Boston Medical Center; HRSA/Maternal and Child Health Bureau
Recruiting - verified June 2011 - Condition: Type 2 Diabetes
Intervention: Behavioral: Exercise group
Sponsors: University of Massachusetts, Worcester; University of Massachusetts, Worcester
Recruiting - verified February 2012 - Condition: Major Depressive Disorder With Psychotic Features
Interventions: Drug: Quetiapine monotherapy; Drug: Quetiapine with SSRI
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified February 2012 - Conditions: HIV; Depression; HIV Infections
Interventions: Behavioral: Cognitive behavioral therapy (CBT) for adherence and depression (CBT-AD); Behavioral: Life-steps adherence treatment; Behavioral: Information and supportive psychotherapy (ISP) for adherence and depression (ISP-AD)
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; National Institute of Mental Health (NIMH)
Recruiting - verified January 2012 - Condition: Depression
Intervention: Behavioral: Telepsychiatry-based Culturally Sensitive Collaborative Treatment
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified April 2012 - Conditions: Major Depressive Disorder; Parkinson's Disease
Interventions: Behavioral: Cognitive Behavioral Therapy; Behavioral: Cognitive Behavioral Therapy
Sponsors: Massachusetts General Hospital; Amy Farabaugh, PhD; Brigham and Women's Hospital; Beth Israel Deaconess Medical Center
Recruiting - verified May 2012 - Condition: Postpartum Depression
Intervention: Drug: Escitalopram
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; Forest Laboratories
Recruiting - verified July 2011 - Condition: Major Depressive Disorder
Intervention: Behavioral: Psychodynamic Psychotherapy
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; Hope for Depression Research Foundation
Recruiting - verified June 2011 - Conditions: Major Depression; Bipolar Disorder
Intervention: Other: Prevalence
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified April 2012 - Conditions: Psychotic Depression; Major Depression With Psychotic Features; Psychosis
Interventions: Drug: mifepristone; Drug: placebo
Sponsors: Corcept Therapeutics; Corcept Therapeutics
Recruiting - verified February 2012 - Condition: Major Depressive Disorder
Interventions: Drug: Ziprasidone; Drug: Placebo
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; Vanderbilt University
Recruiting - verified April 2012 - Conditions: Infant, Newborn; Hypoxia, Brain; Hypoxia-Ischemia, Brain; Encephalopathy, Hypoxic-Ischemic; Hypoxic-Ischemic Encephalopathy; Ischemic-Hypoxic Encephalopathy
Interventions: Procedure: Hypothermia; Procedure: Normothermic Control
Sponsors: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); National Center for Research Resources (NCRR)
Recruiting - verified September 2011 - Conditions: Bipolar Disorder; Bipolar Depression
Interventions: Drug: citalopram + mood stabilizer; Procedure: FDG PET scans; Procedure: MRI structural scans; Procedure: Genotyping; Procedure: Blood Draw; Drug: placebo + mood stabilizer
Sponsors: Tufts Medical Center; Tufts Medical Center; National Institute of Mental Health (NIMH)
Recruiting - verified July 2011
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