- Condition: Major Depressive Disorder
Interventions: Drug: Placebo; Drug: Vilazodone; Drug: Vilazodone
Sponsors: Forest Laboratories; Forest Laboratories
Recruiting - verified April 2012 - Condition: Bipolar Depression
Intervention: Device: Deep TMS (H-Coil)
Sponsors: Brainsway; Brainsway
Not yet recruiting - verified May 2012 - Condition: Depressive Disorder, Major
Interventions: Drug: LuAA21004; Drug: Duloxetine; Drug: Placebo
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Global Research & Development Center, Inc.
Recruiting - verified May 2012 - Condition: Major Depressive Disorder
Interventions: Drug: Ketamine; Drug: Ketamine; Drug: Ketamine; Drug: Ketamine; Drug: Ketamine; Drug: Saline
Sponsors: Columbia University; Columbia University; National Institute of Mental Health (NIMH)
Recruiting - verified March 2012 - Conditions: Dysthymic Disorder; Dysthymia; Depression NOS; Chronic Depressive Disorder
Interventions: Drug: Desvenlafaxine; Drug: Placebo
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; Pfizer
Recruiting - verified February 2012 - Condition: Depression
Interventions: Behavioral: Interpersonal Psychotherapy for Adolescents; Behavioral: Enhanced Care
Sponsors: University of Rochester; University of Rochester; National Institute of Mental Health (NIMH)
Recruiting - verified March 2012 - Condition: Bipolar Depression
Intervention: Drug: Minocycline
Sponsors: Mount Sinai School of Medicine; Mount Sinai School of Medicine
Recruiting - verified January 2012 - Condition: Suicidal Ideation
Interventions: Drug: Ketamine; Drug: Midazolam
Sponsors: Mount Sinai School of Medicine; James Murrough
Recruiting - verified January 2012 - Condition: Major Depressive Disorder
Interventions: Drug: ALKS 5461; Drug: Placebo
Sponsors: Alkermes; Alkermes
Recruiting - verified April 2012 - Condition: Major Depressive Disorder
Interventions: Drug: AZD6765 iv; Drug: AZD6765 iv; Drug: Placebo
Sponsors: AstraZeneca; AstraZeneca
Recruiting - verified February 2012 - Condition: Major Depressive Disorder
Interventions: Drug: Placebo; Drug: Vilazodone; Drug: Vilazodone; Drug: Citalopram
Sponsors: Forest Laboratories; Forest Laboratories
Recruiting - verified March 2012 - Condition: Major Depressive Disorder
Interventions: Drug: cariprazine; Drug: cariprazine; Drug: placebo
Sponsors: Forest Laboratories; Forest Laboratories; Gedeon Richter Ltd.
Recruiting - verified March 2012 - Condition: Acute Depressive Episode
Interventions: Drug: Ramelteon SL; Drug: Ramelteon SL; Drug: Ramelteon SL; Drug: Placebo
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Global Research & Development Center, Inc.
Recruiting - verified March 2012 - Condition: Depression Disorder, Major
Interventions: Drug: RO4995819; Drug: RO4995819; Drug: RO4995819; Drug: Placebo
Sponsors: Hoffmann-La Roche; Hoffmann-La Roche
Recruiting - verified May 2012 - Conditions: Unipolar Depression; Dysthymia
Intervention: Behavioral: IPT-A
Sponsors: Columbia University; Columbia University
Recruiting - verified October 2011 - Conditions: Major Depressive Disorder; Dysthymia
Interventions: Behavioral: Stepped Care IPT-A (SCIPT-A); Behavioral: Treatment as Usual
Sponsors: Columbia University; Columbia University; National Institute of Mental Health (NIMH)
Recruiting - verified September 2011 - Condition: Depression Disorder, Major
Interventions: Drug: RO4917523; Drug: RO4917523; Drug: Placebo
Sponsors: Hoffmann-La Roche; Hoffmann-La Roche
Recruiting - verified May 2012 - Condition: Major Depressive Disorder
Intervention: Device: Genecept Assay
Sponsors: Genomind, LLC; Genomind, LLC
Recruiting - verified December 2011 - Condition: Major Depressive Disorder
Interventions: Drug: Antidepressant + SPD489 (Lisdexamfetamine dimesylate) 10 mg; Drug: Antidepressant + SPD489 (Lisdexamfetamine dimesylate) 30 mg; Drug: Antidepressant + SPD489 (Lisdexamfetamine dimesylate) 50 mg; Drug: Antidepressant + SPD489 (Lisdexamfetamine dimesylate) 70 mg; Drug: Antidepressant + Placebo
Sponsors: Shire Development LLC; Shire Development LLC
Recruiting - verified March 2012 - Condition: Major Depressive Disorder
Interventions: Drug: SPD489 (Lisdexamfetamine dimesylate ); Drug: Placebo
Sponsors: Shire Development LLC; Shire Development LLC
Recruiting - verified May 2012 - Condition: Major Depressive Disorder
Interventions: Drug: Antidepressant + SPD489 (Lisdexamfetamine dimesylate ); Drug: Antidepressant + Placebo
Sponsors: Shire Development LLC; Shire Development LLC
Recruiting - verified March 2012 - Condition: Major Depressive Disorder
Interventions: Drug: desvenlafaxine succinate sustained-release 50 mg/day; Drug: desvenlafaxine succinate sustained-release 100 mg/day; Drug: placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Condition: Fibromyalgia
Interventions: Drug: Pregabalin; Drug: placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Condition: Bipolar Disorder I or II
Intervention: Drug: Tranylcypromine
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute
Recruiting - verified September 2011 - Condition: Premature Birth
Intervention: Behavioral: Family Nurture Intervention
Sponsors: Columbia University; Columbia University; Williams College; New York State Psychiatric Institute
Recruiting - verified September 2011 - Condition: Major Depressive Disorder
Interventions: Drug: tasimelteon; Drug: placebo
Sponsors: Vanda Pharmaceuticals; Vanda Pharmaceuticals
Recruiting - verified May 2012 - Condition: Psychotic Depression
Interventions: Drug: Olanzapine; Drug: Placebo
Sponsors: Weill Medical College of Cornell University; Weill Medical College of Cornell University; University of Toronto; University of Massachusetts, Worcester; University of Pittsburgh
Recruiting - verified March 2012 - Condition: Major Depressive Disorder
Intervention: Drug: Lurasidone
Sponsors: Sunovion; Sunovion
Recruiting - verified April 2012 - Condition: Major Depressive Disorder
Interventions: Drug: Lurasidone 20 mg; Drug: Lurasidone 60 mg; Drug: Placebo
Sponsors: Sunovion; Sunovion
Not yet recruiting - verified November 2011 - Condition: Major Depressive Disorder
Interventions: Drug: Placebo; Drug: Lu AA21004 10 mg; Drug: Lu AA21004 10 mg; Drug: Lu AA21004 20 mg
Sponsors: H. Lundbeck A/S; H. Lundbeck A/S
Recruiting - verified April 2012 - Condition: Major Depressive Disorder With Mixed Features
Interventions: Drug: Lurasidone; Drug: Placebo
Sponsors: Sunovion; Sunovion
Recruiting - verified April 2012 - Conditions: Major Depressive Disorder; Bipolar Disorder
Interventions: Behavioral: Wake Therapy; Device: lightbox; Drug: Lithium Carbonate; Drug: Armodafinil
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute
Recruiting - verified April 2012 - Conditions: Suicidal Ideation; Depression
Interventions: Behavioral: The Senior Connection; Other: Care as Usual
Sponsors: University of Rochester; University of Rochester; Centers for Disease Control and Prevention
Recruiting - verified February 2012 - Condition: Depression
Interventions: Drug: Sertraline; Drug: Placebo; Drug: BupropionXL
Sponsors: University of Texas Southwestern Medical Center; University of Texas Southwestern Medical Center
Recruiting - verified April 2012 - Condition: Depression, Bipolar
Interventions: Drug: Placebo; Drug: Cariprazine; Drug: Cariprazine; Drug: Cariprazine
Sponsors: Forest Laboratories; Forest Laboratories; Gedeon Richter Ltd.
Recruiting - verified March 2012 - Condition: Postpartum Depression
Intervention: Behavioral: Behavioral Intervention for PPD
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute
Recruiting - verified February 2012 - Conditions: Bipolar Affective Disorders; Cyclothymic Disorder; Schizoaffective Disorder; Major Depressive Disorder; Dysthymic Disorder; Obsessive-Compulsive Disorder; Panic Disorder; Posttraumatic Stress Disorder; Premenstrual Dysphoric Disorder; Social Anxiety Disorder
Intervention:
Sponsors: Weill Medical College of Cornell University; Weill Medical College of Cornell University
Recruiting - verified June 2011 - Condition: Major Depressive Disorder
Interventions: Drug: Desvenlafaxine Succinate Sustained-Release; Drug: Desvenlafaxine Succinate Sustained-Release; Drug: Placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Condition: Major Depressive Disorder
Intervention: Drug: DVS SR
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Condition: Major Depressive Disorder
Interventions: Device: NEST-1 (NeoSync EEG Synchronized TMS); Device: SHAM
Sponsors: NeoSync, Inc.; NeoSync, Inc.
Recruiting - verified May 2012 - Condition: Depression
Interventions: Drug: Duloxetine; Drug: Escitalopram; Drug: BMS-820836 Placebo; Drug: BMS-820836; Drug: BMS-820836; Drug: BMS-820836; Drug: BMS-820836
Sponsors: Bristol-Myers Squibb; Bristol-Myers Squibb
Recruiting - verified August 2011 - Condition: Treatment Outcome
Interventions: Drug: Lu AA21004; Drug: Escitalopram
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Global Research & Development Center, Inc.
Recruiting - verified May 2012 - Condition: Depression
Interventions: Drug: Placebo matching with BMS-820836; Drug: BMS-820836; Drug: BMS-820836; Drug: BMS-820836
Sponsors: Bristol-Myers Squibb; Bristol-Myers Squibb
Recruiting - verified July 2011 - Conditions: Depressive Disorder; Depression; Depressive Disorder, Major; Mood Disorders; Mental Disorders
Interventions: Drug: OPC-34712 + ADT; Drug: Placebo + ADT; Drug: Placebo + ADT
Sponsors: Otsuka Pharmaceutical Development & Commercialization, Inc.; Otsuka Pharmaceutical Development & Commercialization, Inc.
Recruiting - verified July 2011 - Conditions: Depressive Disorder; Depression; Depressive Disorder, Major; Mood Disorders; Mental Disorders
Interventions: Drug: OPC-34712 + ADT; Drug: Placebo + ADT; Drug: Placebo + ADT
Sponsors: Otsuka Pharmaceutical Development & Commercialization, Inc.; Otsuka Pharmaceutical Development & Commercialization, Inc.
Recruiting - verified July 2011 - Conditions: Depression; Dementia; Geriatrics
Interventions: Behavioral: Problem Adaptation Therapy (PATH); Behavioral: Supportive Therapy
Sponsors: Weill Medical College of Cornell University; Weill Medical College of Cornell University; National Institute of Mental Health (NIMH)
Recruiting - verified May 2012 - Condition: Major Depressive Disorder
Interventions: Drug: PNB01 fixed dose combination of pipamperone and citalopram; Drug: Citalopram; Drug: Pipamperone
Sponsors: PharmaNeuroBoost N.V.; PharmaNeuroBoost N.V.
Recruiting - verified March 2012 - Condition: Major Depressive Disorder
Interventions: Drug: Ketamine; Drug: placebo
Sponsors: Mount Sinai School of Medicine; James Murrough
Recruiting - verified December 2011 - Condition: Major Depressive Disorder
Interventions: Drug: LY2216684; Drug: Placebo
Sponsors: Eli Lilly and Company; Eli Lilly and Company
Recruiting - verified May 2012 - Condition: Depression
Interventions: Drug: Duloxetine; Drug: Placebo matching with BMS-820836; Drug: BMS-820836; Drug: Duloxetine; Drug: Placebo matching with Duloxetine
Sponsors: Bristol-Myers Squibb; Bristol-Myers Squibb
Recruiting - verified February 2012 - Condition: Dementia
Interventions: Behavioral: New York University Caregiver Intervention (NYUCI); Behavioral: Community-based case management using community health workers (CHWs).
Sponsors: Columbia University; Columbia University; National Institutes of Health (NIH)
Recruiting - verified September 2011 - Conditions: Breast Cancer; Depression; Fatigue; Sleep Disorders
Interventions: Drug: metformin hydrochloride; Genetic: DNA analysis; Genetic: RNA analysis; Genetic: polymerase chain reaction; Genetic: polymorphism analysis; Genetic: reverse transcriptase-polymerase chain reaction; Other: enzyme-linked immunosorbent assay; Other: laboratory biomarker analysis; Other: questionnaire administration; Procedure: quality-of-life assessment
Sponsors: National Cancer Institute (NCI); National Surgical Adjuvant Breast and Bowel Project (NSABP); National Cancer Institute (NCI)
Recruiting - verified February 2012 - Condition: Bipolar
Interventions: Drug: Lurasidone; Drug: Placebo
Sponsors: Sunovion; Sunovion
Recruiting - verified April 2012 - Condition: Treatment Resistant Depression
Interventions: Drug: CX157; Drug: Placebo
Sponsors: CeNeRx BioPharma Inc.; CeNeRx BioPharma Inc.
Recruiting - verified October 2011 - Conditions: Borderline Personality Disorder; Major Depression
Intervention:
Sponsors: State University of New York - Upstate Medical University; State University of New York - Upstate Medical University; Syracuse University
Recruiting - verified November 2011 - Condition: Major Depressive Disorder (MDD)
Interventions: Drug: LY2216684; Drug: Placebo
Sponsors: Eli Lilly and Company; Eli Lilly and Company
Recruiting - verified May 2012 - Condition: Major Depressive Disorder
Interventions: Drug: LY2216684; Drug: Placebo
Sponsors: Eli Lilly and Company; Eli Lilly and Company
Recruiting - verified May 2012 - Conditions: Infant, Newborn; Hypoxia, Brain; Hypoxia-Ischemia, Brain; Encephalopathy, Hypoxic-Ischemic; Hypoxic-Ischemic Encephalopathy; Ischemic-Hypoxic Encephalopathy
Intervention: Procedure: Whole-body Cooling
Sponsors: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); National Center for Research Resources (NCRR)
Recruiting - verified February 2012 - Condition: Major Depressive Disorder
Interventions: Drug: LY2216684; Drug: Placebo
Sponsors: Eli Lilly and Company; Eli Lilly and Company
Recruiting - verified May 2012 - Condition: Major Depression
Interventions: Behavioral: Interpersonal Psychotherapy; Behavioral: Problem-Solving Therapy; Behavioral: Brief Supportive Psychotherapy
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute
Recruiting - verified February 2012 - Condition: Depression
Intervention: Drug: Armodafinil
Sponsors: Teva Pharmaceutical Industries; Cephalon
Recruiting - verified May 2012 - Condition: Depression
Interventions: Drug: Armodafinil; Drug: Armodafinil; Drug: Placebo
Sponsors: Teva Pharmaceutical Industries; Cephalon
Recruiting - verified May 2012 - Condition: Major Depressive Disorder
Intervention: Drug: tranylcypromine
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute of Mental Health (NIMH)
Recruiting - verified December 2011 - Condition: Depression
Interventions: Behavioral: Shared Decision Making; Other: Usual Care
Sponsors: Weill Medical College of Cornell University; Weill Medical College of Cornell University; National Institute of Mental Health (NIMH)
Recruiting - verified February 2012 - Condition: Depression
Interventions: Drug: lithium and Venlafaxine; Procedure: ECT
Sponsors: Mount Sinai School of Medicine; Mount Sinai School of Medicine; National Institute of Mental Health (NIMH)
Recruiting - verified March 2012 - Conditions: Breast Cancer; Prostate Cancer; Lung Cancer; Lymphoma Cancer; Gynecological Cancers
Interventions: Behavioral: group intervention and questionnaires; Behavioral: individual phone intervention and questionnaires
Sponsors: Memorial Sloan-Kettering Cancer Center; Memorial Sloan-Kettering Cancer Center
Recruiting - verified December 2011 - Condition: Depressive Disorder, Major
Interventions: Dietary Supplement: Omega 3 Fatty Acids; Dietary Supplement: Corn oil
Sponsors: New York University School of Medicine; New York University School of Medicine
Recruiting - verified December 2011 - Conditions: Ischemic Stroke; Depression
Interventions: Behavioral: Ecosystem Focused Therapy (EFT); Behavioral: Education in stroke and depression
Sponsors: Weill Medical College of Cornell University; Weill Medical College of Cornell University; National Institute of Mental Health (NIMH)
Recruiting - verified February 2012 - Conditions: Bipolar; Depression
Intervention: Drug: lurasidone
Sponsors: Sunovion; Sunovion
Recruiting - verified April 2012 - Conditions: Alcohol Dependence; Depression
Interventions: Behavioral: Interpersonal Psychotherapy for Co-occurring Alcohol Dependence and Major Depression (IPT-ADMD); Behavioral: Treatment as Usual
Sponsors: University of Rochester; University of Rochester; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified February 2012 - Conditions: Depression; Bipolar Disorder
Interventions: Drug: Liothyronine (T3); Drug: placebo
Sponsors: North Shore Long Island Jewish Health System; North Shore Long Island Jewish Health System; National Alliance for Research on Schizophrenia and Depression
Recruiting - verified June 2011 - Conditions: Stress Disorders, Post-Traumatic; PTSD; Depression; Anxiety Disorder
Interventions: Drug: Midazolam; Drug: Ketamine
Sponsors: Mount Sinai School of Medicine; Dennis Charney; Department of Defense
Recruiting - verified March 2012 - Condition: Major Depressive Disorder
Interventions: Drug: Antidepressants through Texas Medication Algorithm (TMA); Behavioral: Brief Interpersonal Psychotherapy (IPT-B)
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute of Mental Health (NIMH)
Recruiting - verified February 2012 - Condition: Major Depressive Disorder
Interventions: Drug: Escitalopram; Drug: Sertraline; Drug: Venlafaxine XR
Sponsors: BRC Operations Pty. Ltd.; BRC Operations Pty. Ltd.
Recruiting - verified March 2012 - Conditions: Psychotic Depression; Major Depression With Psychotic Features; Psychosis
Interventions: Drug: mifepristone; Drug: placebo
Sponsors: Corcept Therapeutics; Corcept Therapeutics
Recruiting - verified February 2012 - Conditions: Infant, Newborn; Hypoxia, Brain; Hypoxia-Ischemia, Brain; Encephalopathy, Hypoxic-Ischemic; Hypoxic-Ischemic Encephalopathy; Ischemic-Hypoxic Encephalopathy
Interventions: Procedure: Hypothermia; Procedure: Normothermic Control
Sponsors: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); National Center for Research Resources (NCRR)
Recruiting - verified September 2011 - Conditions: Pulmonary Disease, Chronic Obstructive; Depression
Interventions: Behavioral: Problem-solving therapy (PST); Behavioral: Adherence-enhanced procedures (AE)
Sponsors: National Institute of Mental Health (NIMH); National Institute of Mental Health (NIMH)
Recruiting - verified August 2011 - Condition: Depression
Interventions: Drug: Standard antidepressant therapy (SADT); Behavioral: Motivational antidepressant therapy (MADT)
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute of Mental Health (NIMH)
Recruiting - verified March 2012 - Condition: Depression
Interventions: Behavioral: Problem-solving therapy (PST); Behavioral: Case management (CM)
Sponsors: Weill Medical College of Cornell University; Weill Medical College of Cornell University; National Institute of Mental Health (NIMH)
Recruiting - verified February 2012 - Condition: Depression
Interventions: Drug: Escitalopram; Drug: Desipramine
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute of Mental Health (NIMH)
Recruiting - verified April 2012 - Condition: Epilepsy
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified September 2011 - Condition: Depression
Interventions: Drug: Paroxetine CR for major depressive episode; Drug: Bupropion XL for major depressive episode
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute of Mental Health (NIMH)
Recruiting - verified February 2012 - Conditions: Cocaine Dependence; Depression
Interventions: Drug: Mirtazapine; Drug: Placebo
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute on Drug Abuse (NIDA)
Recruiting - verified October 2011
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