- Conditions: Type II Diabetes; Diabetes Mellitus
Interventions: Behavioral: Education on risk factors for Type II Diabetes; Behavioral: Education on Type II Diabetes; Behavioral: Education on regular visits to a Primary Care Provider
Sponsors: Ethnicity and Disease Community Empowerment Center; Ethnicity and Disease Community Empowerment Center; Steward Carney Hospital; Boston Public Housing Authority
Not yet recruiting - verified May 2012 - Condition: Diabetic Nephropathies
Interventions: Drug: Allopurinol; Drug: Placebo
Sponsors: Joslin Diabetes Center; Alessandro Doria; Steno Diabetes Center; University of Michigan; University of Minnesota - Clinical and Translational Science Institute
Not yet recruiting - verified April 2012 - Conditions: Diabetes; Diabetes Mellitus, Type 2
Interventions: Drug: insulin degludec; Drug: insulin glargine
Sponsors: Novo Nordisk; Novo Nordisk
Recruiting - verified April 2012 - Conditions: Diabetes Mellitus; Diabetes Mellitus Complications; Gastroparesis
Interventions: Drug: RM-131; Drug: Placebo
Sponsors: Rhythm Pharmaceuticals, Inc.; Rhythm Pharmaceuticals, Inc.
Recruiting - verified May 2012 - Condition: Type 2 Diabetes Mellitus
Interventions: Other: Text messages; Other: Usual care
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; McKesson Foundation
Not yet recruiting - verified March 2012 - Conditions: Diabetic Polyneuropathy; Weight Loss
Intervention: Other: Weight Achievement and Intensive Treatment (Why WAIT)
Sponsors: Joslin Diabetes Center; Joslin Diabetes Center; NeuroMetrix, Inc.
Not yet recruiting - verified March 2012 - Conditions: Diabetes; Effects of Liraglutide Administration on Brain Activity; Weight Loss; Hunger
Interventions: Drug: Liraglutide; Drug: Placebo
Sponsors: Beth Israel Deaconess Medical Center; Beth Israel Deaconess Medical Center
Recruiting - verified March 2012 - Condition: Obesity
Interventions: Drug: Exenatide; Drug: Placebo; Behavioral: Dietary counseling
Sponsors: Beth Israel Deaconess Medical Center; Eleftheria Maratos-Flier; Amylin Pharmaceuticals, Inc.
Recruiting - verified May 2012 - Condition: Type 1 Diabetes
Intervention: Drug: ferumoxytol
Sponsors: Massachusetts General Hospital; Jason Gaglia; National Institute of Allergy and Infectious Diseases (NIAID); Harvard University
Recruiting - verified January 2012 - Condition: Diabetes Mellitus, Type 2
Interventions: Drug: Placebo; Drug: PF-04937319 10 mg; Drug: PF-04937319 50 mg; Drug: PF-04937319 100 mg; Drug: Glimepiride
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Conditions: Diabetes; Diabetes Mellitus, Type 1
Interventions: Drug: insulin degludec; Drug: insulin detemir; Drug: insulin aspart
Sponsors: Novo Nordisk; Novo Nordisk
Recruiting - verified May 2012 - Condition: Type 2 Diabetes
Interventions: Drug: "GLIPULIN:" [insulin glargine, metformin, exenatide (GLP-1-agonist)]; Drug: Insulin glargine, metformin, prandial insulin
Sponsors: University of Washington; University of Washington; Eli Lilly and Company; Sanofi-Aventis; Amylin Pharmaceuticals, Inc.; DexCom, Inc.; Bayer; Medicomp; University of Texas; Department of Veterans Affairs; Biomedical Research Institute of New Mexico
Not yet recruiting - verified February 2012 - Condition: Type 1 Diabetes
Interventions: Behavioral: Parent education with human patient simulator; Behavioral: Standard care
Sponsors: University of Massachusetts, Worcester; University of Massachusetts, Worcester
Recruiting - verified January 2012 - Condition: Type 2 Diabetes Mellitus
Interventions: Device: Proteus Sustained Behavior Change system; Drug: Regularly prescribed diabetes medicines (metformin, sulfonylureas, thiazolidinediones, DPP-IV inhibitors, alpha-glucosidase inhibitors)
Sponsors: Proteus Biomedical, Inc.; Proteus Biomedical, Inc.
Not yet recruiting - verified December 2011 - Condition: Diabetes Mellitus, Type 2
Intervention: Other: Diabetes Transitions Tool Kit
Sponsors: Massachusetts General Hospital; Deborah Wexler, MD; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified January 2012 - Condition: Diabetic Peripheral Neuropathy
Interventions: Drug: DS-5565 tablet; Drug: pregabalin capsule; Drug: Placebo
Sponsors: Daiichi Sankyo Inc.; Daiichi Sankyo Inc.
Recruiting - verified March 2012 - Conditions: Type 2 Diabetes Mellitus; Chronic Kidney Disease
Interventions: Drug: CTP-499; Drug: Placebo
Sponsors: Concert Pharmaceuticals; Concert Pharmaceuticals
Recruiting - verified March 2012 - Conditions: Hypertension; Diabetes
Interventions: Dietary Supplement: L-Arginine; Dietary Supplement: Placebo Supplement
Sponsors: Brigham and Women's Hospital; Brigham and Women's Hospital
Recruiting - verified April 2012 - Condition: Type 2 Diabetes Mellitus
Interventions: Drug: Sitagliptin; Drug: Atorvastatin; Other: Placebo to sitagliptin; Other: Placebo to atorvastatin; Drug: Metformin; Drug: Glimepiride; Drug: Placebo to glimepiride
Sponsors: Merck; Merck
Recruiting - verified May 2012 - Condition: Type 1 Diabetes
Intervention: Behavioral: CGM Family Teamwork
Sponsors: Joslin Diabetes Center; Joslin Diabetes Center; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Jaeb Center for Health Research
Recruiting - verified November 2011 - Condition: Diabetes
Intervention: Drug: Glargine
Sponsors: Joslin Diabetes Center; Joslin Diabetes Center; Sanofi-Aventis
Recruiting - verified November 2011 - Condition: Diabetic Peripheral Neuropathy
Interventions: Drug: Pregabalin; Other: placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Conditions: Gastroparesis; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2
Interventions: Drug: Placebo; Drug: 10mg TZP-102; Drug: 20mg TZP-102
Sponsors: Tranzyme, Inc.; Tranzyme, Inc.
Recruiting - verified April 2012 - Condition: Painful Diabetic Peripheral Neuropathy
Interventions: Drug: pregabalin; Drug: placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Condition: Type 2 Diabetes
Interventions: Drug: Technosphere Insulin; Drug: Technosphere Inhalation Powder
Sponsors: Mannkind Corporation; Mannkind Corporation
Recruiting - verified May 2012 - Condition: Diabetes Mellitus, Type 2
Interventions: Drug: Placebo matching with Saxagliptin; Drug: Metformin IR; Drug: Metformin XR; Drug: Saxagliptin; Drug: Saxagliptin
Sponsors: Bristol-Myers Squibb; Bristol-Myers Squibb; AstraZeneca
Not yet recruiting - verified February 2012 - Condition: Diabetes Mellitus, Type 2
Interventions: Drug: Glargine; Drug: LY2605541
Sponsors: Eli Lilly and Company; Eli Lilly and Company; Boehringer Ingelheim Pharmaceuticals
Recruiting - verified May 2012 - Condition: Diabetes Mellitus, Type 2
Interventions: Drug: BI 10773; Drug: BI 10773; Drug: BI 10773; Drug: linagliptin; Drug: BI 10773 linagliptin FDC; Drug: BI 10773 linagliptin FDC; Drug: high dose BI 10773 placebo; Drug: high dose BI 10773 placebo; Drug: high dose BI 10773 placebo; Drug: low dose BI 10773 placebo; Drug: low dose BI 10773 placebo; Drug: low dose BI 10773 placebo; Drug: linagliptin; Drug: linagliptin; Drug: high dose FDC placebo; Drug: high dose FDC placebo; Drug: high dose FDC placebo; Drug: high dose FDC placebo; Drug: low dose FDC placebo; Drug: low dose FDC placebo; Drug: low dose FDC placebo; Drug: linagliptin placebo; Drug: linagliptin placebo; Drug: linagliptin placebo; Drug: BI 10773; Drug: BI 10773 high dose; Drug: BI 10773 low dose
Sponsors: Boehringer Ingelheim Pharmaceuticals; Boehringer Ingelheim Pharmaceuticals; Eli Lilly and Company
Recruiting - verified May 2012 - Conditions: Lower Extremity Chronic Ulcers; Diabetes Mellitus
Interventions: Biological: Curexcell; Biological: Sham injection
Sponsors: Macrocure Ltd.; Macrocure Ltd.; Averion International Corporation
Recruiting - verified September 2011 - Condition: Type 1 Diabetes Mellitus
Intervention: Drug: Atazanavir
Sponsors: Brigham and Women's Hospital; Brigham and Women's Hospital; National Institutes of Health (NIH)
Not yet recruiting - verified August 2011 - Condition: Type 1 Diabetes Mellitus
Interventions: Procedure: Closed-loop therapy; Procedure: Standard Insulin Pump Therapy
Sponsors: Children's Hospital Boston; Children's Hospital Boston
Recruiting - verified August 2011 - Conditions: Hypertension; Diabetes Mellitus
Intervention: Other: Self-monitoring-nurse-primary care provider feedback loop
Sponsors: University of Massachusetts, Worcester; University of Massachusetts, Worcester; Reliant Medical Group; University of Massachusetts, Amherst
Recruiting - verified February 2012 - Conditions: Wounds; Diabetes Complications; Diabetic Foot; Foot Ulcer
Intervention: Other: Online Wound Electronic Medical Record
Sponsors: New York University School of Medicine; New York University School of Medicine; Agency for Healthcare Research and Quality (AHRQ)
Recruiting - verified March 2012 - Conditions: Hypertension; Stage 2 Hypertension; Diabetes
Interventions: Drug: Valturna + amlodipine; Drug: valturna + placebo; Drug: Valturna + chlorthalidone
Sponsors: Novartis; Novartis
Recruiting - verified May 2012 - Conditions: Cerebral Edema; Diabetic Ketoacidosis
Interventions: Other: Intravenous fluid; Other: intravenous fluid; Other: intravenous fluid; Other: Intravenous fluid
Sponsors: University of California, Davis; University of California, Davis; Children's Hospital of Philadelphia; Washington University School of Medicine; University of Utah; Children's Research Institute; Children's Hospital Boston; Columbia University; University of Colorado, Denver; Nationwide Children's Hospital; Children's Memorial Hospital; Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - verified June 2011 - Conditions: Diabetes; Diabetic Retinopathy
Intervention: Behavioral: Diabetes Education
Sponsors: Diabetic Retinopathy Clinical Research Network; Diabetic Retinopathy Clinical Research Network; National Eye Institute (NEI); National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified April 2012 - Condition: Diabetes Mellitus
Interventions: Drug: Metformin; Drug: Placebo
Sponsors: University of Massachusetts, Worcester; University of Massachusetts, Worcester
Recruiting - verified April 2012 - Condition: Type 2 Diabetes
Interventions: Behavioral: virtual world; Behavioral: face to face
Sponsors: Boston Medical Center; Boston Medical Center; University of Massachusetts, Worcester
Recruiting - verified July 2011 - Condition: Diabetes Mellitus, Type 1
Interventions: Drug: Sirolimus; Drug: Tacrolimus; Drug: Mycophenolate mofetil; Drug: Mycophenolic acid
Sponsors: National Institute of Allergy and Infectious Diseases (NIAID); National Institute of Allergy and Infectious Diseases (NIAID); Immune Tolerance Network (ITN)
Available - verified April 2012 - Conditions: Chronic Kidney Disease; Hypertension; Diabetes
Intervention: Behavioral: Exercise training
Sponsors: Springfield College; Springfield College
Recruiting - verified January 2011 - Condition: Diabetic Foot Ulcers
Interventions: Device: Epiflo; Other: Moist Wound Therapy
Sponsors: Ogenix Corporation; Ogenix Corporation
Recruiting - verified December 2011 - Conditions: Obesity; Type 2 Diabetes; Metabolic Syndrome
Intervention:
Sponsors: Joslin Diabetes Center; Joslin Diabetes Center
Recruiting - verified April 2012 - Condition: Type 2 Diabetes Mellitus
Interventions: Drug: Welchol for oral suspension placebo proxy; Drug: Welchol for oral suspension
Sponsors: Daiichi Sankyo Inc.; Daiichi Sankyo Inc.
Recruiting - verified April 2012 - Conditions: Renal Insufficiency, Chronic; Diabetes Mellitus, Type 2
Interventions: Drug: Placebo; Drug: Bardoxolone Methyl: 20 mg
Sponsors: Reata Pharmaceuticals, Inc.; Reata Pharmaceuticals, Inc.
Recruiting - verified May 2012 - Condition: Gastroparesis
Interventions: Drug: GSK962040 (5 mg tablet); Drug: GSK962040 (25 mg tablet); Drug: GSK962040 (125 mg tablet); Drug: Placebo
Sponsors: GlaxoSmithKline; GlaxoSmithKline
Recruiting - verified April 2012 - Condition: Diabetes Mellitus, Type 2
Interventions: Drug: glimepride placebo; Drug: linagliptin placebo; Drug: linagliptin; Drug: glimepiride
Sponsors: Boehringer Ingelheim Pharmaceuticals; Boehringer Ingelheim Pharmaceuticals; Eli Lilly and Company
Recruiting - verified May 2012 - Condition: Foot Ulcer, Diabetic
Intervention: Device: PriMatrix
Sponsors: TEI Biosciences Inc.; TEI Biosciences Inc.; Beth Israel Deaconess Medical Center
Recruiting - verified June 2011 - Condition: Diabetes Mellitus, Type 2
Interventions: Drug: Insulin lispro; Drug: Glargine
Sponsors: Eli Lilly and Company; Eli Lilly and Company
Recruiting - verified May 2012 - Condition: Diabetes Mellitus, Type 1
Interventions: Drug: liraglutide; Drug: placebo
Sponsors: Novo Nordisk; Novo Nordisk
Recruiting - verified April 2012 - Condition: Type 2 Diabetes
Interventions: Drug: Saxagliptin; Drug: Placebo (Saxagliptin); Drug: Metformin IR; Drug: Placebo (Metformin); Drug: Metformin (Active Rescue)
Sponsors: Bristol-Myers Squibb; Bristol-Myers Squibb; AstraZeneca
Recruiting - verified February 2012 - Condition: Type 2 Diabetes
Interventions: Drug: Dapagliflozin; Drug: Placebo matching Dapagliflozin
Sponsors: Bristol-Myers Squibb; Bristol-Myers Squibb; AstraZeneca
Recruiting - verified November 2011 - Condition: Type 2 Diabetes Mellitus
Intervention: Drug: Intranasal insulin
Sponsors: Beth Israel Deaconess Medical Center; Beth Israel Deaconess Medical Center; University of Washington; University of Arkansas; VA Boston Healthcare System; University of Massachusetts, Worcester
Recruiting - verified June 2011 - Condition: Type 2 Diabetes
Interventions: Drug: Dapagliflozin; Drug: Placebo matching Dapagliflozin
Sponsors: Bristol-Myers Squibb; Bristol-Myers Squibb; AstraZeneca
Recruiting - verified November 2011 - Condition: Diabetic Foot Ulcers
Interventions: Drug: Santyl; Other: White Petrolatum
Sponsors: Healthpoint; Healthpoint
Recruiting - verified December 2011 - Condition: Diabetes Mellitus, Type 2
Interventions: Drug: Placebo BI 10773 low dose; Drug: Placebo BI 10773 low dose; Drug: Placebo BI 10773 high dose; Drug: Placebo BI 10773 high dose; Drug: BI 10773 low dose; Drug: BI 10773 high dose
Sponsors: Boehringer Ingelheim Pharmaceuticals; Boehringer Ingelheim Pharmaceuticals; Eli Lilly and Company
Recruiting - verified May 2012 - Conditions: Type 2 Diabetes Mellitus; Obesity
Interventions: Procedure: Laparoscopic Adjustable Gastric Band; Procedure: Roux-en-Y Gastric Bypass (Surgery); Other: Intensive Medical Diabetes & Weight Management; Device: Allergan Adjustable Gastric Band
Sponsors: Joslin Diabetes Center; Allison Goldfine; Brigham and Women's Hospital
Recruiting - verified March 2012 - Condition: Foot Ulcer, Diabetic
Interventions: Device: Integra® Dermal Regeneration Template; Other: Conventional Wound Therapy
Sponsors: Integra LifeSciences Corporation; Integra LifeSciences Corporation
Recruiting - verified August 2011 - Condition: Diabetes Mellitus, Type 2
Interventions: Drug: Aleglitazar; Drug: Placebo
Sponsors: Hoffmann-La Roche; Hoffmann-La Roche
Recruiting - verified March 2012 - Condition: Type 2 Diabetes
Intervention: Behavioral: Exercise group
Sponsors: University of Massachusetts, Worcester; University of Massachusetts, Worcester
Recruiting - verified February 2012 - Conditions: Diabetes; Obesity; Metabolic Syndrome; Cardiovascular Disease
Interventions: Other: Carbohydrate; Other: Carbohydrate Load; Other: Carbohydrate plus Protein; Other: Carbohydrate plus Fat; Other: Fiber
Sponsors: Tufts University; Tufts University; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified November 2011 - Condition: Type I Diabetes
Interventions: Behavioral: Education; Device: CGM; Behavioral: Problem Solving; Behavioral: Social Learning; Behavioral: Behavior Modification
Sponsors: National Institutes of Health Clinical Center (CC); Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - verified February 2012 - Conditions: Vitreous Hemorrhage; Proliferative Diabetic Retinopathy
Interventions: Drug: Ranibizumab; Behavioral: Saline
Sponsors: Diabetic Retinopathy Clinical Research Network; Diabetic Retinopathy Clinical Research Network; National Eye Institute (NEI)
Recruiting - verified February 2012 - Conditions: Diabetes Mellitus, Type 2; Acute Coronary Syndrome
Interventions: Drug: Alogliptin; Drug: Placebo
Sponsors: Takeda Global Research & Development Center, Inc.; Takeda Global Research & Development Center, Inc.
Recruiting - verified March 2012 - Condition: Diabetic Foot Ulcer
Interventions: Drug: HO/03/03 10µg; Drug: Placebo
Sponsors: HealOr; HealOr; Clinigene International Ltd; Cato Research
Recruiting - verified December 2011 - Condition: Diabetes Mellitus, Type I
Interventions: Biological: Purified Pancreatic Islets; Drug: Etanercept
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified January 2012 - Conditions: Type 2 Diabetes Mellitus; Vascular Disease
Interventions: Drug: Spironolactone; Drug: hydrochlorothiazide + potassium; Other: placebo
Sponsors: Brigham and Women's Hospital; Brigham and Women's Hospital; National Institutes of Health (NIH)
Recruiting - verified June 2011 - Condition: Type 2 Diabetes Mellitus
Interventions: Drug: Sitagliptin phosphate; Drug: Placebo
Sponsors: Merck; Merck; Duke Clinical Research Institute, Oxford Diabetes Trials Unit
Recruiting - verified May 2012 - Condition: Type 2 Diabetes Mellitus
Interventions: Drug: Welchol; Drug: placebo tablets
Sponsors: Daiichi Sankyo Inc.; Daiichi Sankyo Inc.
Recruiting - verified January 2012 - Conditions: Diabetes Mellitus; Healthy Volunteers
Intervention:
Sponsors: Beth Israel Deaconess Medical Center; Beth Israel Deaconess Medical Center; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified June 2011 - Condition: Type 2 Diabetes
Intervention:
Sponsors: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified May 2011 - Conditions: Kidney Disease; Nephropathy; Type 2 Diabetes
Interventions: Drug: losartan; Drug: lisinopril; Drug: losartan
Sponsors: Department of Veterans Affairs; Department of Veterans Affairs
Recruiting - verified May 2012 - Conditions: Psoriasis; Metabolic Syndrome; Hyperlipidemia; Obesity; Hypertension
Intervention: Drug: Etanercept
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; Amgen
Recruiting - verified February 2012 - Condition: Diabetes Mellitus, Type 1
Intervention: Drug: Oral Insulin
Sponsors: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); National Institute of Allergy and Infectious Diseases (NIAID); National Center for Research Resources (NCRR); American Diabetes Association; Juvenile Diabetes Research Foundation
Recruiting - verified February 2012 - Condition: Diabetes Mellitus, Type 1
Intervention:
Sponsors: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); National Center for Research Resources (NCRR); Juvenile Diabetes Research Foundation; American Diabetes Association
Recruiting - verified March 2012 - Conditions: Stroke; Myocardial Infarction; Diabetes
Interventions: Drug: pioglitazone; Drug: placebo
Sponsors: Yale University; Yale University; National Institute of Neurological Disorders and Stroke (NINDS); Takeda Pharmaceuticals North America, Inc.
Recruiting - verified August 2011
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