- Conditions: Substance-Related Disorders; Drug Addiction; Substance Abuse
Interventions: Behavioral: Home-Based Intervention; Behavioral: Educational Group
Sponsors: Treatment Research Institute; Treatment Research Institute; University of Minnesota - Clinical and Translational Science Institute
Recruiting - verified April 2012 - Conditions: Cannabis Dependence; Marijuana Dependence
Interventions: Drug: Dronabinol; Drug: Clonidine; Drug: Placebo
Sponsors: Mclean Hospital; Mclean Hospital; Brain and Behavior Research Foundation (formerly NARSAD)
Recruiting - verified May 2012 - Condition: Cocaine Dependence
Interventions: Drug: Oxytocin; Drug: Saline
Sponsors: Medical University of South Carolina; Medical University of South Carolina
Not yet recruiting - verified April 2012 - Condition: Drug Abuse/Dependence
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Conditions: Nicotine Withdrawal; Tobacco Abstinence
Intervention: Device: tDCS, prefrontal cortex and parietal cortex
Sponsors: Yale University; Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified March 2012 - Conditions: Cognition Disorders; Cocaine Dependence; ADHD
Intervention: Other: repetitive Transcranial Magnetic Stimulation (rTMS)
Sponsors: University of Sao Paulo General Hospital; University of Sao Paulo General Hospital
Recruiting - verified May 2012 - Conditions: Chronic Pain; Opioid Addiction
Interventions: Other: Yoga; Behavioral: Educational Counseling
Sponsors: Yale University; Yale University
Recruiting - verified April 2012 - Condition: Heroin Addiction
Interventions: Drug: JITAI Combined with psychological intervention; Drug: Methadone; Drug: Traditional Chinese Medicine JITAI
Sponsors: Shanghai Mental Health Center; Shanghai Mental Health Center; Shanghai Center of Biomedicine Development
Recruiting - verified April 2012 - Condition: Nicotine Dependence
Interventions: Drug: Oxytocin; Drug: placebo
Sponsors: Medical University of South Carolina; Kevin Gray
Not yet recruiting - verified April 2012 - Condition: Marijuana Dependence
Interventions: Drug: Vilazodone; Drug: Placebo
Sponsors: Medical University of South Carolina; Medical University of South Carolina; National Institute on Drug Abuse (NIDA)
Not yet recruiting - verified April 2012 - Condition: Opioid Related Disorder
Interventions: Drug: RBP-6300; Drug: Placebo
Sponsors: Reckitt Benckiser Pharmaceuticals, Inc; Reckitt Benckiser Pharmaceuticals, Inc
Recruiting - verified February 2012 - Condition: Nicotine Dependence
Intervention: Drug: Intravenous Nicotine
Sponsors: Mclean Hospital; Mclean Hospital; National Institute on Drug Abuse (NIDA)
Recruiting - verified May 2012 - Condition: Alcoholism
Interventions: Drug: Ondansetron + Brief Behavioral Enhancement Treatment; Drug: Placebo + Brief Behavioral Enhancement Treatment
Sponsors: University of Virginia; Bankole Johnson; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Not yet recruiting - verified May 2012 - Condition: Methamphetamine Dependence
Intervention: Behavioral: Text messages
Sponsors: New Leaf Treatment Center; New Leaf Treatment Center
Recruiting - verified April 2012 - Condition: Induced Pluripotent Stem Cells
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Conditions: Smoking Cessation; Smoking; Nicotine Dependence
Interventions: Behavioral: Incentives for abstinence and treatment engagement; Behavioral: Attendance incentive
Sponsors: University of Wisconsin, Madison; University of Wisconsin, Madison
Not yet recruiting - verified May 2012 - Conditions: Smoking Cessation; Smoking; Nicotine Dependence
Interventions: Behavioral: Incentives for abstinence and treatment engagement; Behavioral: Attendance incentive
Sponsors: University of Wisconsin, Madison; University of Wisconsin, Madison
Not yet recruiting - verified May 2012 - Conditions: Cigarette Smoking; Tobacco Use Disorder; Nicotine Dependence; Smoking Cessation
Intervention: Behavioral: Smoking Cessation Decision Aids
Sponsors: Seoul National University Hospital; Seoul National University Hospital; Pfizer
Not yet recruiting - verified March 2012 - Conditions: Cannabis Dependence; Psychosis
Intervention:
Sponsors: Hadassah Medical Organization; Hadassah Medical Organization
Not yet recruiting - verified April 2012 - Conditions: Cigarette Smoking; Nicotine Dependence
Interventions: Drug: varenicline (Chantix); Drug: bupropion (Zyban) & nicotine patches; Drug: nicotine patches
Sponsors: Duke University; Duke University; Philip Morris USA, Inc.
Recruiting - verified May 2012 - Conditions: Cocaine Dependence; Opioid Dependence; Alcoholism; Pathological Gamblers; Adolescents
Intervention:
Sponsors: Yale University; Yale University; National Institutes of Health (NIH); National Institute on Drug Abuse (NIDA)
Recruiting - verified March 2012 - Condition: Nicotine Dependence
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Condition: Alcohol Dependance
Intervention: Other: rTMS (repetitive transcranial magnetic stimulation)
Sponsors: Institut National de la Santé Et de la Recherche Médicale, France; Institut National de la Santé Et de la Recherche Médicale, France
Recruiting - verified March 2012 - Conditions: Traumatic Brain Injury; Substance Abuse; Substance Dependence
Interventions: Drug: Citicoline; Drug: Omega-3; Other: Rice bran oil; Other: Microcrystalline Cellulose
Sponsors: University of Utah; Deborah Yurgelun-Todd
Not yet recruiting - verified January 2012 - Conditions: Depression; Alcohol Dependence
Intervention: Drug: Ketalar (ketamine)
Sponsors: Yale University; Yale University; VA Connecticut Healthcare System
Recruiting - verified April 2012 - Condition: Opiate Dependence
Interventions: Drug: Vivitrol; Behavioral: Employment based opiate abstinence reinforcement; Other: Usual Care Control
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute on Drug Abuse (NIDA)
Not yet recruiting - verified March 2012 - Condition: Opioid Dependence
Interventions: Behavioral: Distress Tolerance; Behavioral: Health Education
Sponsors: Butler Hospital; Butler Hospital
Not yet recruiting - verified March 2012 - Condition: Low Back Pain
Interventions: Drug: Methadone; Drug: Buprenorphine/naloxone
Sponsors: State University of New York at Buffalo; State University of New York at Buffalo
Recruiting - verified March 2012 - Conditions: Cocaine Dependence; Cocaine Addiction; Cocaine Abuse; Substance Abuse
Interventions: Behavioral: Sitting; Behavioral: Running; Behavioral: Walking
Sponsors: Baylor College of Medicine; Baylor College of Medicine; National Institute on Drug Abuse (NIDA)
Recruiting - verified May 2012 - Conditions: Methamphetamine Dependence; Methamphetamine Abuse; Substance Abuse
Interventions: Drug: Placebo; Drug: Varenicline; Drug: Varenicline
Sponsors: Baylor College of Medicine; Baylor College of Medicine; National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2012 - Conditions: Opioid Withdrawal; Physical Dependence
Intervention: Drug: Ondansetron
Sponsors: Stanford University; Stanford University; National Institute on Drug Abuse (NIDA)
Recruiting - verified March 2012 - Conditions: Heroin Dependence; Opioid-Related Disorders
Intervention:
Sponsors: Wayne State University; Wayne State University; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Condition: Alcohol Dependence
Intervention: Drug: Psilocybin
Sponsors: University of New Mexico; University of New Mexico; Heffter Research Institute
Recruiting - verified February 2012 - Conditions: Breast Cancer; Tobacco Dependence
Interventions: Drug: placebo; Drug: varenicline
Sponsors: Memorial Sloan-Kettering Cancer Center; Memorial Sloan-Kettering Cancer Center; Pfizer
Recruiting - verified February 2012 - Conditions: Alcoholism; Alcohol Abuse; Smoking; Alcohol Drinking
Intervention: Drug: Varenicline
Sponsors: Yale University; Yale University; Columbia University
Not yet recruiting - verified March 2012 - Conditions: Opioid-related Disorders; Opiate Dependence; Opiate Addiction; Opiate Abuse
Intervention: Genetic: COMT polymorphism
Sponsors: Assistance Publique - Hôpitaux de Paris; Assistance Publique - Hôpitaux de Paris
Not yet recruiting - verified April 2012 - Conditions: Depressive Disorder; Major Depressive Disorder; Dysthymic Disorder; Alcohol-Related Disorders; Alcoholism
Intervention: Behavioral: Cognitive Behavioral Analysis System of Psychotherapy
Sponsors: University of Virginia; University of Virginia
Recruiting - verified February 2012 - Condition: Substance Dependence
Intervention: Other: No intervention
Sponsors: Federal University of São Paulo; Federal University of São Paulo; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.; Associação Fundo de Incentivo à Pesquisa
Not yet recruiting - verified March 2012 - Condition: COCAINE-RELATED DISORDERS
Interventions: Drug: d-cycloserine; Drug: sugar pill
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Conditions: Alcohol Abuse; Posttraumatic Stress Disorder
Interventions: Drug: Prazosin; Drug: Placebo medication
Sponsors: Seattle Institute for Biomedical and Clinical Research; Seattle Institute for Biomedical and Clinical Research; National Institute on Alcohol Abuse and Alcoholism (NIAAA); VA Puget Sound Health Care System
Recruiting - verified December 2011 - Condition: Nicotine Dependence
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified November 2011 - Condition: Opioid-Related Disorders
Interventions: Drug: Pioglitazone; Drug: Placebo
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified November 2011 - Condition: Opioid Dependence
Interventions: Drug: Aprepitant; Drug: Placebo pill
Sponsors: New York University; New York University; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Condition: Nicotine Dependence
Intervention: Drug: Varenicline or placebo
Sponsors: University of Pennsylvania; University of Pennsylvania; National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)
Recruiting - verified February 2012 - Condition: Nicotine Dependence
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified October 2011 - Condition: Alcohol Dependence
Intervention:
Sponsors: Charite University, Berlin, Germany; Charite University, Berlin, Germany; Central Institute of Mental Health, Mannheim; University Hospital, Bonn
Recruiting - verified January 2012 - Condition: Cocaine Dependence
Interventions: Drug: Ketamine; Drug: Lorazepam (control)
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2012 - Conditions: Cannabis Dependence; Psychostimulant Dependence
Intervention: Drug: Risperidone
Sponsors: Tel-Aviv Sourasky Medical Center; Tel-Aviv Sourasky Medical Center
Not yet recruiting - verified January 2012 - Condition: Nicotine Dependence
Interventions: Drug: Varenicline; Drug: placebo
Sponsors: Medical University of South Carolina; Medical University of South Carolina
Not yet recruiting - verified December 2011 - Condition: Alcohol Dependence
Intervention:
Sponsors: Centre Hospitalier Esquirol; Centre Hospitalier Esquirol
Recruiting - verified April 2012 - Condition: Cocaine Dependence
Intervention: Drug: lisdexamfetamine
Sponsors: University of Minnesota - Clinical and Translational Science Institute; University of Minnesota - Clinical and Translational Science Institute
Recruiting - verified December 2011 - Conditions: Alcohol Use Disorders; Bipolar Disorder
Interventions: Drug: Zonisamide; Drug: Placebo
Sponsors: VA Connecticut Healthcare System; VA Connecticut Healthcare System; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Not yet recruiting - verified May 2012 - Condition: Cocaine Dependence
Intervention: Drug: Lisdexamfetamine
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute on Drug Abuse (NIDA)
Recruiting - verified May 2012 - Conditions: Tobacco Dependence; Cessation of Smoking
Intervention: Other: electronic mail
Sponsors: Jordi Gol i Gurina Foundation; Jordi Gol i Gurina Foundation; Preventive Services and Health Promotion Research Network; Public Health Service of Cataluña; Carlos III Health Institute
Not yet recruiting - verified January 2012 - Conditions: Nicotine Dependence; Smoking Cessation
Interventions: Drug: EVP-6124; Drug: Placebo Capsule; Drug: NicoDerm CQ Patch (Active); Drug: NRT Patch (Placebo); Behavioral: Brief Supportive and Behavioral Treatment
Sponsors: Massachusetts General Hospital; A. Eden Evins; EnVivo Pharmaceuticals, Inc.; National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2012 - Conditions: Alcohol Abuse; Alcohol Dependence; Drug Abuse; Drug Dependence
Intervention: Behavioral: Integrated Twelve-Step Facilitation
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified April 2012 - Conditions: Adolescents; Conduct Disorder; Vulnerability to Substance Addicition
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Not yet recruiting - verified May 2012 - Conditions: Opioid-Related Disorders; Heroin Dependence
Intervention: Drug: Naltrexone
Sponsors: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA); Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA); ZonMw: The Netherlands Organisation for Health Research and Development; Alkermes
Not yet recruiting - verified November 2011 - Condition: Cannabis Dependence
Intervention: Drug: Guanfacine
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute
Not yet recruiting - verified December 2011 - Condition: Cocaine Dependence
Interventions: Drug: levodopa carbidopa and entacapone (LCE); Drug: Placebo
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute
Not yet recruiting - verified December 2011 - Condition: Substance-Related Disorders
Interventions: Behavioral: Substance Abuse Education; Behavioral: Mind-body Bridging
Sponsors: University of Utah; University of Utah
Recruiting - verified April 2012 - Condition: Cocaine Dependence
Interventions: Drug: Citalopram; Drug: Citalopram; Drug: Placebo
Sponsors: The University of Texas Health Science Center, Houston; Joy Schmitz; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Conditions: Heroin Addiction; Substance Use Disorders
Interventions: Behavioral: Strength-based case management; Behavioral: Control condition - referral only
Sponsors: Region Skane; Region Skane; Swedish Council for Working Life and Social Research
Recruiting - verified December 2011 - Condition: Opioid Dependence
Intervention: Drug: VIVITROL 380mg
Sponsors: Alkermes; Alkermes
Recruiting - verified November 2011 - Conditions: Opioid Dependence; Heroin Dependence
Interventions: Drug: Hydromorphone, Injectable; Drug: Diacetylmorphine, injectable; Drug: Hydromorphone, liquid oral; Drug: Diacetylmorphine, liquid oral
Sponsors: University of British Columbia; University of British Columbia; Canadian Institutes of Health Research (CIHR); Providence HealthCare
Not yet recruiting - verified October 2011 - Condition: Amphetamine-Related Disorders
Interventions: Drug: extended-release naltrexone; Drug: Placebo
Sponsors: National Institute on Drug Abuse (NIDA); National Institute on Drug Abuse (NIDA); Alkermes
Not yet recruiting - verified October 2011 - Conditions: Substance Abuse; Substance Dependence; Cognitive Impairment
Interventions: Behavioral: Cognitive Training + Work Therapy; Behavioral: Work Therapy
Sponsors: Yale University; Yale University
Recruiting - verified August 2011 - Conditions: Cannabis Dependence; Cannabis Abuse
Intervention: Drug: N-acetylcystein
Sponsors: Assistance Publique - Hôpitaux de Paris; Assistance Publique - Hôpitaux de Paris
Not yet recruiting - verified January 2012 - Conditions: Alcohol Dependence; Anxiety
Interventions: Drug: Doxazosin; Drug: Placebo
Sponsors: Brown University; Brown University; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified September 2011 - Condition: Opiate Dependence
Interventions: Other: Patient-Centered Methadone Treatment; Other: Methadone Treatment as usual
Sponsors: Friends Research Institute, Inc.; Friends Research Institute, Inc.
Recruiting - verified September 2011 - Conditions: Contraceptive Usage; Opioid Dependence
Interventions: Behavioral: Contraceptive management program; Other: Usual care
Sponsors: University of Vermont; University of Vermont
Recruiting - verified December 2011 - Condition: Opioid Dependence
Intervention:
Sponsors: Alkermes; Alkermes
Recruiting - verified April 2012 - Condition: Nicotine Dependence
Interventions: Behavioral: Tailored treatment; Behavioral: Standard Treatment
Sponsors: Yale University; Yale University; National Institutes of Health (NIH)
Recruiting - verified March 2012 - Conditions: HIV; Drug Addiction
Interventions: Behavioral: Psycho-education; Behavioral: Experimental
Sponsors: RTI International; RTI International; University of Cape Town
Recruiting - verified December 2011 - Condition: Opiate Dependence
Intervention: Behavioral: employment based reinforcement
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2010 - Conditions: Human Immunodeficiency Virus; Acquired Immunodeficiency Syndrome; Opiate Addiction; Drug Dependence
Intervention: Drug: Buprenorphine/naloxone
Sponsors: Yale University; Yale University; George Mason University; Howard University
Recruiting - verified April 2012 - Conditions: Nicotine Dependence; Opiate Dependence
Interventions: Behavioral: Intensive, tailored intervention; Behavioral: NJ Quitline Referral
Sponsors: University of Medicine and Dentistry New Jersey; University of Medicine and Dentistry New Jersey; National Institute on Drug Abuse (NIDA)
Recruiting - verified January 2012 - Conditions: Severe Mental Illness; Nicotine Dependence
Interventions: Behavioral: Electronic decision support system with CO monitor feedback; Behavioral: Electronic decision support system without CO monitor feedback
Sponsors: Dartmouth-Hitchcock Medical Center; Dartmouth-Hitchcock Medical Center; U.S. Department of Education; Bristol-Myers Squibb
Recruiting - verified March 2012 - Condition: Nicotine Dependence
Intervention:
Sponsors: Medical University of South Carolina; Medical University of South Carolina
Recruiting - verified July 2011 - Conditions: Alcohol Dependence; Alcoholism; Alcohol Abuse; Alcohol Use Disorder; PTSD; Posttraumatic Stress Disorder
Interventions: Drug: Topiramate; Drug: Placebo
Sponsors: University of Maryland; University of Maryland; Department of Veterans Affairs
Not yet recruiting - verified August 2011 - Condition: Cocaine Dependence
Interventions: Drug: Buprenorphine + Naltrexone; Drug: Placebo + Naltrexone
Sponsors: University of California, Los Angeles; Walter Ling; National Institute on Drug Abuse (NIDA); The EMMES Corporation
Recruiting - verified February 2012 - Condition: Cocaine Dependence
Interventions: Drug: Oral tacrine; Drug: Oral placebo
Sponsors: Midwest Biomedical Research Foundation; Midwest Biomedical Research Foundation
Not yet recruiting - verified May 2012 - Conditions: Substance Related Disorders; Drug Addiction; Substance Abuse
Interventions: Behavioral: Cash CM; Behavioral: Voucher CM; Behavioral: Non-CM Control
Sponsors: Treatment Research Institute; Treatment Research Institute; National Institute on Drug Abuse (NIDA)
Recruiting - verified July 2011 - Conditions: Stress Disorders, Post-Traumatic; Substance-Related Disorders
Interventions: Behavioral: Concurrent Treatment of PTSD and Substance Dependence; Behavioral: Relapse Prevention Treatment
Sponsors: The City College of New York; The City College of New York; National Institute on Drug Abuse (NIDA)
Recruiting - verified June 2011 - Conditions: Heroin Dependence; Nicotine Dependence
Interventions: Drug: Pioglitazone; Drug: Placebo
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute on Drug Abuse (NIDA); Omeros Corporation
Recruiting - verified July 2011 - Condition: Cocaine Dependence
Interventions: Drug: levodopa/carbidopa; Drug: Ropinirole; Drug: Placebo
Sponsors: The University of Texas Health Science Center, Houston; The University of Texas Health Science Center, Houston
Recruiting - verified February 2012 - Conditions: Nicotine Dependence; Symptoms of Anxiety; HIV
Intervention: Behavioral: Integrated cognitive-behavioral therapy for smoking cessation and anxiety
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; Southern Methodist University; University of Houston
Recruiting - verified July 2011 - Conditions: Cocaine Abuse or Dependence; Cocaine Related Disorders
Intervention:
Sponsors: Wayne State University; Wayne State University
Recruiting - verified October 2011 - Condition: Opiate Dependence
Interventions: Drug: Vivitrol; Drug: Naltrexone (oral); Behavioral: BDRC; Behavioral: Medical Management
Sponsors: Yale University; Yale University; St. Petersburg State Pavlov Medical University; National Institute on Drug Abuse (NIDA)
Not yet recruiting - verified July 2011 - Condition: Alcoholism
Interventions: Behavioral: SMART Recovery face-to-face meetings; Behavioral: Overcoming Addictions web application
Sponsors: Behavior Therapy Associates, LLP; Behavior Therapy Associates, LLP; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified September 2011 - Condition: Opioid Dependence
Interventions: Drug: Opioid detoxification using buprenorphine vs. oral naltrexone; Drug: Buprenorphine
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute
Recruiting - verified June 2011 - Conditions: HIV; Opiate Dependence
Interventions: Behavioral: Abstinence-reinforcing contingency management intervention; Behavioral: Performance Feedback intervention
Sponsors: Albert Einstein College of Medicine of Yeshiva University; Albert Einstein College of Medicine of Yeshiva University; National Institute on Drug Abuse (NIDA); The City University of New York
Not yet recruiting - verified June 2011 - Conditions: Substance-Related Disorders; Drug Addiction; Substance Abuse
Interventions: Behavioral: Community Reinforcement and Family Training; Behavioral: Al-Anon Facilitation
Sponsors: Treatment Research Institute; Treatment Research Institute; Robert J. Meyers PhD & Associates
Recruiting - verified December 2011 - Conditions: Methamphetamine Dependence; Substance Abuse; Methamphetamine Abuse
Interventions: Drug: Varenicline; Drug: Placebo
Sponsors: University of California, Los Angeles; University of California, Los Angeles
Recruiting - verified March 2012 - Condition: Nicotine Dependence
Interventions: Drug: Varenicline; Drug: Bupropion; Drug: Nicotine patches
Sponsors: Duke University; Duke University; National Institute on Drug Abuse (NIDA)
Recruiting - verified January 2012 - Condition: Nicotine Dependence
Interventions: Behavioral: Standard treatment; Behavioral: Standard treatment+practice quitting
Sponsors: Rutgers University; Rutgers University; National Institute on Drug Abuse (NIDA)
Recruiting - verified June 2011 - Conditions: Chronic Pain; Opioid Dependence
Interventions: Drug: Varenicline; Drug: Placebo
Sponsors: Mayo Clinic; Mayo Clinic
Recruiting - verified May 2012 - Condition: Opioid Dependence
Intervention: Drug: Fentanyl
Sponsors: University of Adelaide; University of Adelaide
Not yet recruiting - verified May 2011 - Condition: Cocaine Dependence
Interventions: Procedure: Transcranial Magnetic Stimulation; Procedure: Placebo TMS
Sponsors: University of Sao Paulo General Hospital; University of Sao Paulo General Hospital
Recruiting - verified August 2010 - Condition: Opiate Dependence
Interventions: Behavioral: Behavioral Drug and HIV Risk Reduction Counseling; Behavioral: Educational Counseling; Behavioral: Treatment as Usual
Sponsors: Yale University; Yale University; Centers for Disease Control and Prevention, China
Recruiting - verified July 2011 - Conditions: Smoking; Tobacco Dependence; Alcohol Dependence
Interventions: Drug: Varenicline; Drug: placebo
Sponsors: Mayo Clinic; Mayo Clinic
Recruiting - verified April 2012 - Conditions: Cannabis Dependence; Marijuana Dependence
Interventions: Drug: Nabilone; Drug: Placebo
Sponsors: Mclean Hospital; Mclean Hospital; National Institute on Drug Abuse (NIDA)
Recruiting - verified January 2012 - Conditions: Substance Abuse; Substance Dependence; Alcohol Abuse; Drug Use; Relapse
Interventions: Behavioral: Dual Processing; Behavioral: Relapse Prevention
Sponsors: Inova Health Care Services; Inova Health Care Services; Virginia Commonwealth University; Georgetown University
Recruiting - verified August 2011 - Condition: Alcohol Dependence
Interventions: Drug: Valproate; Drug: Naltrexone
Sponsors: Department of Veterans Affairs; Department of Veterans Affairs
Recruiting - verified March 2012 - Condition: Drug Addiction
Intervention: Drug: Varenicline
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Not yet recruiting - verified December 2011 - Conditions: Nicotine Dependence; Bipolar Disorder
Interventions: Behavioral: Counseling/Healthy Lifestyle; Behavioral: Counseling/Managing Mood
Sponsors: University of Cincinnati; University of Cincinnati; National Institute on Drug Abuse (NIDA)
Recruiting - verified March 2012 - Conditions: HIV; Medication Adherence; Substance Dependence
Intervention: Behavioral: Spiritual Self-Schema Therapy
Sponsors: Hunter College; Hunter College; Fordham University
Recruiting - verified February 2011 - Conditions: Alcoholism; Cocaine Dependence
Interventions: Drug: Vigabatrin; Drug: Placebo
Sponsors: University of Pennsylvania; University of Pennsylvania
Recruiting - verified August 2011 - Conditions: Chronic Pain; Opiate Dependence
Interventions: Behavioral: Cognitive-Behavioral Therapy for Pain and Opioid Dependence; Behavioral: Methadone Drug Counseling
Sponsors: Yale University; Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified May 2012 - Conditions: Alcohol Dependence; Executive Dysfunction; Abnormal Craving for Drugs
Intervention: Device: transcranial Direct Current Stimulation
Sponsors: Federal University of Espirito Santo; Federal University of Espirito Santo; Harvard University; University of Göttingen
Recruiting - verified October 2010 - Condition: Marijuana Dependence
Interventions: Drug: Nicotine; Drug: Placebo Patch
Sponsors: Southern Illinois University Carbondale; Southern Illinois University Carbondale; National Institute on Drug Abuse (NIDA)
Recruiting - verified March 2012 - Condition: Nicotine Dependence
Interventions: Drug: Varenicline; Drug: Bupropion; Drug: Nicotine patches; Drug: Nicotine Inhaler
Sponsors: Duke University; Duke University; National Institute on Drug Abuse (NIDA); Philip Morris USA, Inc.
Recruiting - verified March 2012 - Conditions: Alcohol Dependence; Alcohol Abuse
Interventions: Drug: Naltrexone; Behavioral: Brenda Therapy Sessions
Sponsors: University of North Carolina, Chapel Hill; University of North Carolina, Chapel Hill; National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Institutes of Health (NIH)
Recruiting - verified January 2012 - Condition: Alcohol Dependence
Interventions: Drug: Aripiprazole; Drug: Placebo
Sponsors: Medical University of South Carolina; Medical University of South Carolina; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified April 2012 - Conditions: Elevated Risk of Cardiovascular Disease;; Tobacco Dependence
Interventions: Other: Virtual Clinician Research Tool (VCRT); Other: No VCRT, only physician counseling at visits
Sponsors: University of Rochester; University of Rochester; National Institute on Drug Abuse (NIDA)
Recruiting - verified August 2011 - Conditions: HIV; AIDS; Opioid Dependence; Drug Dependence
Intervention: Drug: Depot Naltrexone
Sponsors: Yale University; Yale University; Baystate Medical Center
Recruiting - verified August 2011 - Condition: Cocaine Dependence
Intervention: Drug: Buspirone
Sponsors: The University of Texas Health Science Center, Houston; The University of Texas Health Science Center, Houston
Recruiting - verified March 2012 - Conditions: Alcoholism; Alcohol Abuse; Alcohol Dependence
Interventions: Drug: Dutasteride; Drug: placebo
Sponsors: University of Connecticut Health Center; University of Connecticut Health Center; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified December 2011 - Conditions: Alcohol Abuse; Alcohol Dependence
Interventions: Drug: ondansetron; Drug: placebo ondansetron; Drug: Ondansetron
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified February 2012 - Conditions: Cocaine Dependence; Crack Cocaine Dependence
Interventions: Drug: Biperiden; Drug: Placebo
Sponsors: Federal University of São Paulo; Federal University of São Paulo; Nacional Conseling of Scientific Development and Technology, Brazil; Association for Psychopharmacological Research, Brazil
Recruiting - verified March 2012 - Conditions: Tobacco Use Disorder; Smoking Relapse; Cognitive Training; Nicotine Addiction
Interventions: Behavioral: Cognitive Remediation Training (CRT); Behavioral: Standard Care (SC)
Sponsors: University of Pennsylvania; University of Pennsylvania
Recruiting - verified January 2012 - Conditions: Cocaine Abuse; Cocaine Dependence; Postpartum Period
Interventions: Drug: Progesterone; Other: Placebo
Sponsors: Yale University; Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Conditions: PTSD; Substance Addiction
Interventions: Behavioral: Prolonged Exposure; Behavioral: Motivational Enhancement Therapy
Sponsors: Department of Veterans Affairs; Department of Veterans Affairs
Recruiting - verified March 2012 - Condition: Nicotine Dependence
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified August 2011 - Condition: Nicotine Dependence
Interventions: Drug: Baclofen 30 mg/day; Drug: placebo pill; Drug: Baclofen 60 mg/day
Sponsors: Centre for Addiction and Mental Health; Centre for Addiction and Mental Health; Canadian Tobacco Control Research Initiative
Recruiting - verified December 2011 - Conditions: Alcohol-Related Disorders; Alcohol Dependence; Alcoholism; Anxiety Disorder
Interventions: Drug: Pexacerfont; Drug: Placebo
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified August 2011 - Conditions: Methamphetamine-dependence; Substance Abuse
Interventions: Drug: Ibudilast; Drug: Ibudilast; Drug: Ibudilast
Sponsors: University of California, Los Angeles; University of California, Los Angeles; National Institute on Drug Abuse (NIDA); MediciNova
Recruiting - verified March 2012 - Condition: Alcoholism
Interventions: Drug: N-acetylcysteine + high-dose naltrexone (150 mg); Drug: High-dose naltrexone (150 mg) alone; Drug: Low-dose naltrexone (50 mg) alone
Sponsors: Department of Veterans Affairs; Department of Veterans Affairs
Recruiting - verified March 2012 - Conditions: Tobacco Dependence; Smoking Cessation
Interventions: Drug: Varenicline; Drug: Placebo; Drug: Varenicline
Sponsors: Queen Mary University of London; Queen Mary University of London
Recruiting - verified July 2011 - Condition: Alcohol Dependence
Interventions: Drug: GSK561679; Drug: Placebo
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified November 2011 - Condition: Nicotine Dependence
Intervention: Behavioral: Smoking Cessation Counseling
Sponsors: University of Pennsylvania; University of Pennsylvania; National Cancer Institute (NCI)
Recruiting - verified January 2012 - Conditions: Opioid Related Disorders; Opioid Dependence; Opioid Addiction
Interventions: Drug: Buprenorphine/naloxone; Drug: Clonidine; Drug: Tramadol ER
Sponsors: National Institute on Drug Abuse (NIDA); National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2012 - Conditions: Alcohol Dependence; Nicotine Dependence
Interventions: Drug: Topiramate with brief behavioral enhancement therapy; Drug: Placebo plus brief behavioral enhancement therapy
Sponsors: University of Virginia; University of Virginia; National Institute on Alcohol Abuse and Alcoholism (NIAAA); M.D. Anderson Cancer Center; University of California, San Diego
Recruiting - verified March 2012 - Conditions: Cocaine; Alcohol Dependence
Interventions: Drug: Aprepitant; Drug: Placebo
Sponsors: University of Pennsylvania; University of Pennsylvania; National Institute on Drug Abuse (NIDA)
Recruiting - verified August 2011 - Conditions: Cocaine Dependence; Cocaine Withdrawal
Interventions: Drug: controlled release carvedilol; Drug: Placebo
Sponsors: University of Arkansas; University of Arkansas; National Institute on Drug Abuse (NIDA); Baylor College of Medicine
Recruiting - verified May 2012 - Conditions: Drug Addiction; Nicotine Dependence
Intervention: Drug: Nicotrol
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified September 2011 - Condition: Alcohol Dependence
Interventions: Drug: Quetiapine XR plus mirtazapine; Drug: Quetiapine fumarate extended release (Quetiapine XR)
Sponsors: Dartmouth-Hitchcock Medical Center; Dartmouth-Hitchcock Medical Center
Recruiting - verified February 2012 - Conditions: Tobacco Use Disorder; Nicotine Dependence
Interventions: Behavioral: text messaging for smoking cessation; Behavioral: Generic text messages
Sponsors: The Miriam Hospital; The Miriam Hospital; Live Inspired, LLC
Recruiting - verified April 2012 - Condition: Cocaine Dependence
Interventions: Drug: Zonisamide; Drug: Placebo; Drug: Cocaine Hydrochloride; Behavioral: Neurocognitive and Performance Battery; Behavioral: Smoking Assessments
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute on Drug Abuse (NIDA)
Recruiting - verified June 2011 - Condition: Opiate Dependence
Intervention: Drug: Methadone, naloxone
Sponsors: Kuopio University Hospital; Kuopio University Hospital
Not yet recruiting - verified March 2012 - Conditions: Alcohol Dependence; Cocaine Dependence
Interventions: Drug: Varenicline; Drug: Placebo
Sponsors: University of Pennsylvania; University of Pennsylvania; National Institute on Drug Abuse (NIDA)
Recruiting - verified August 2011 - Condition: Nicotine Dependence
Interventions: Drug: Varenicline; Behavioral: Individual counseling; Behavioral: Check-ins with medical staff; Behavioral: individual counseling
Sponsors: University of California, San Francisco; University of California, San Francisco; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Condition: Cocaine Dependence
Intervention: Drug: Varenicline
Sponsors: University of Pennsylvania; University of Pennsylvania; National Institute on Drug Abuse (NIDA)
Recruiting - verified August 2011 - Condition: Alcohol-dependence
Intervention: Drug: Naltrexone
Sponsors: Tel-Aviv Sourasky Medical Center; Tel-Aviv Sourasky Medical Center; Ministry of Health, Israel
Not yet recruiting - verified March 2012 - Condition: Alcohol Dependence
Intervention: Drug: Topiramate
Sponsors: Chiang Mai University; Chiang Mai University
Recruiting - verified June 2010 - Condition: Cocaine Dependence
Interventions: Drug: Mifepristone; Drug: placebo
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute
Recruiting - verified December 2011 - Conditions: Smoking; ADHD
Intervention:
Sponsors: Duke University; Duke University; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Conditions: Cannabis Abuse; Cannabis Dependence
Interventions: Drug: Topiramate; Drug: Placebo
Sponsors: Brown University; Brown University; National Institute on Drug Abuse (NIDA)
Recruiting - verified July 2011 - Condition: Drug Dependence
Intervention: Drug: 2-4 of the drugs listed below
Sponsors: University of Arkansas; University of Arkansas; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Condition: Tobacco Dependence
Intervention: Drug: nicotine patch
Sponsors: University of Massachusetts, Worcester; University of Massachusetts, Worcester
Recruiting - verified April 2012 - Conditions: Drug Abuse; Drug Dependence
Intervention:
Sponsors: Nantes University Hospital; Nantes University Hospital
Recruiting - verified January 2010 - Conditions: Alcohol Dependence; Problem Drinking; Hazardous Drinking; Human Immunodeficiency Virus; AIDS
Interventions: Drug: Vivitrol- Intramuscular naltrexone (depot-formulation); Drug: Placebo
Sponsors: Yale University; Yale University; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified August 2011 - Conditions: Methamphetamine Dependence; Methamphetamine Abuse; Substance Abuse
Interventions: Drug: Perindopril; Drug: Placebo; Drug: Candesartan
Sponsors: Baylor College of Medicine; Baylor College of Medicine; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Conditions: Alcohol Dependence; PTSD
Interventions: Drug: Propranolol; Drug: Placebo
Sponsors: Medical University of South Carolina; Medical University of South Carolina; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified November 2011 - Conditions: Nicotine Dependence; Smoking; Sleep Disorders, Intrinsic
Intervention: Behavioral: Exercise
Sponsors: University of Pittsburgh; University of Pittsburgh; National Institute on Drug Abuse (NIDA)
Recruiting - verified May 2012 - Condition: Opioid Dependence
Interventions: Drug: Memantine; Drug: Memantine; Drug: Placebo
Sponsors: University of Massachusetts, Worcester; University of Massachusetts, Worcester; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Condition: Nicotine Dependence
Intervention: Drug: Transdermal nicotine patch
Sponsors: University of Pennsylvania; University of Pennsylvania; National Institute on Drug Abuse (NIDA)
Recruiting - verified December 2011 - Condition: Nicotine Dependence
Interventions: Drug: Bupropion SR; Drug: Nicotine; Drug: Placebo pill and Placebo Patch; Other: Delayed-Quit Control
Sponsors: Southern Illinois University Carbondale; Southern Illinois University Carbondale; National Institute on Drug Abuse (NIDA)
Recruiting - verified September 2011 - Conditions: Cocaine Dependence; Cocaine Addiction; Cocaine Abuse; Substance Abuse
Interventions: Drug: Placebo; Drug: Rivastigmine; Drug: Huperzine A; Drug: Rivastigmine; Drug: Huperzine A
Sponsors: Baylor College of Medicine; Baylor College of Medicine; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Conditions: Drug Abuse; Cocaine Dependence
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA); National Institute of Mental Health (NIMH)
Recruiting - verified July 2011 - Conditions: Drug Abuse; Nicotine Dependence
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified June 2011 - Condition: Cocaine Dependence
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA); University of Maryland
Recruiting - verified July 2011 - Conditions: Nicotine Dependence; Schizophrenia
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified August 2011 - Condition: Nicotine Dependence
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified January 2011 - Condition: Nicotine Dependence
Intervention: Device: Transcranial Magnetic Stimulation
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA); University of Maryland
Recruiting - verified December 2011 - Condition: Opioid Dependence
Interventions: Drug: injectable naltrexone plus dronabinol; Drug: Naltrexone plus placebo
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute on Drug Abuse (NIDA)
Recruiting - verified May 2012 - Conditions: Cannabis Dependence; Marijuana Dependence
Interventions: Drug: Lofexidine and Dronabinol; Drug: Placebo
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2012 - Condition: Opiate Addiction
Interventions: Drug: Buprenorphine/naloxone; Drug: Naltrexone
Sponsors: State University of New York at Buffalo; State University of New York at Buffalo
Recruiting - verified February 2011 - Condition: Drug Dependence
Intervention: Drug: Oxytocin Nasal Spray
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified July 2011 - Condition: Opiate Dependence
Intervention: Behavioral: Linkage
Sponsors: Butler Hospital; Butler Hospital; Boston Medical Center
Recruiting - verified March 2012 - Conditions: Cannabis Dependence; Cannabis Withdrawal; Cognitive Deficits
Interventions: Drug: gabapentin 1200mg/day; Drug: Placebo
Sponsors: The Scripps Research Institute; The Scripps Research Institute
Recruiting - verified March 2012 - Condition: Cocaine Dependence
Interventions: Drug: TA-CD Vaccination; Other: Placebo Injection
Sponsors: Baylor College of Medicine; Baylor College of Medicine; National Institute on Drug Abuse (NIDA); US Department of Veterans Affairs Cooperative Studies Program; VA Maryland Health Care System; Columbia University; VA New York Harbor Healthcare System; University of Pennsylvania; Johns Hopkins University; University of Cincinnati; Celtic Pharma Development Services
Recruiting - verified September 2011 - Condition: Tobacco Dependence
Interventions: Behavioral: Brief Intervention; Behavioral: Extended Treatment; Behavioral: Usual Care
Sponsors: University of California, San Francisco; University of California, San Francisco; National Institute of Mental Health (NIMH)
Recruiting - verified January 2012 - Conditions: Drug Abuse; Cocaine Dependence
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified March 2012 - Conditions: Cocaine Abuse or Dependence; Cocaine Related Disorders
Intervention:
Sponsors: Wayne State University; Wayne State University; National Institute on Drug Abuse (NIDA)
Recruiting - verified October 2011 - Conditions: Cigarette Smoking; Nicotine Dependence; Post-traumatic Stress Disorder; Tobacco Use Disorder
Interventions: Drug: Varenicline; Behavioral: Medication Management Counseling; Behavioral: Prolonged Exposure
Sponsors: University of Pennsylvania; University of Pennsylvania; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Condition: Alcohol Dependence
Interventions: Drug: Pregabalin; Drug: Duloxetine; Behavioral: Standardized behavioral therapy; Behavioral: Standardized behavioral therapy; Drug: Placebo; Behavioral: Standardized behavioral therapy
Sponsors: The Scripps Research Institute; The Scripps Research Institute; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified June 2011 - Condition: Alcohol Dependence
Interventions: Drug: Drug; Drug: Placebo
Sponsors: Medical University of South Carolina; Medical University of South Carolina; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified April 2012 - Conditions: Nicotine Dependence; Smoking Cessation
Interventions: Other: Varenicline and smoking cessation counseling; Behavioral: Exercise or relaxation treatment
Sponsors: University of Connecticut Health Center; University of Connecticut Health Center; National Institutes of Health (NIH); National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2012 - Conditions: Post-traumatic Stress Disorder; Alcohol Dependence
Intervention: Behavioral: stress
Sponsors: Yale University; Elizabeth Ralevski
Recruiting - verified January 2012 - Conditions: HIV Infections; Tobacco Dependence
Interventions: Drug: Varenicline; Drug: Placebo
Sponsors: French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS); French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS); Pfizer
Recruiting - verified May 2012 - Condition: Opiate Addiction
Interventions: Other: Brief Intervention with Buprenorphine initiation; Behavioral: Brief Intervention
Sponsors: Yale University; Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified December 2011 - Conditions: HIV Infections; Drug Abuse
Interventions: Drug: Disulfiram; Drug: Disulfiram + Efavirenz; Drug: Disulfiram + Atazanavir; Drug: Disulfiram + Ritonavir
Sponsors: University of California, San Francisco; University of California, San Francisco; National Institute on Drug Abuse (NIDA)
Recruiting - verified June 2011 - Conditions: Alcoholism; Alcohol Dependence; Post-Tramatic Stress Disorder; fMRI
Intervention: Drug: Aprepitant
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified December 2011 - Condition: Marijuana Dependence
Interventions: Drug: Buspirone; Drug: Placebo
Sponsors: Medical University of South Carolina; Medical University of South Carolina; National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2012 - Conditions: Domestic Violence; Substance Abuse
Interventions: Behavioral: substance abuse/domestic violence treatment; Behavioral: Cognitive behavioral therapy addressing substance abuse
Sponsors: VU University of Amsterdam; VU University of Amsterdam
Recruiting - verified January 2012 - Conditions: Alcoholism; Alcohol Dependence; Alcohol Abuse
Interventions: Drug: topiramate; Drug: zonisamide; Drug: Levetiracetam; Drug: Placebo
Sponsors: Boston Medical Center; Boston Medical Center; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified May 2011 - Conditions: Tobacco Use Cessation; Alcohol-related Disorders
Intervention: Behavioral: behavioral counseling plus contingency management
Sponsors: Yale University; Yale University; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified January 2012 - Conditions: Alcohol Dependence; Depression
Interventions: Behavioral: Interpersonal Psychotherapy for Co-occurring Alcohol Dependence and Major Depression (IPT-ADMD); Behavioral: Treatment as Usual
Sponsors: University of Rochester; University of Rochester; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified February 2012 - Conditions: HIV; Substance Abuse; HIV Infections
Interventions: Behavioral: Intensive Case Management; Drug: Buprenorphine; Behavioral: Money Management
Sponsors: Yale University; Yale University
Recruiting - verified June 2011 - Condition: Alcohol Dependence
Interventions: Drug: naltrexone; Drug: Placebo
Sponsors: University of Pennsylvania; University of Pennsylvania; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified August 2011 - Condition: Nicotine Dependence
Intervention: Behavioral: Tobacco Research and Intervention Program
Sponsors: H. Lee Moffitt Cancer Center and Research Institute; H. Lee Moffitt Cancer Center and Research Institute; National Institutes of Health (NIH)
Recruiting - verified January 2012 - Condition: Alcoholism
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Mental Health (NIMH)
Recruiting - verified June 2011 - Condition: Cocaine Dependence
Interventions: Drug: Galantamine; Drug: placebo
Sponsors: Yale University; Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2012 - Conditions: Cocaine Dependence; Cocaine-Related Disorders; Opioid-Related Disorders
Interventions: Drug: Airipiprazole; Drug: Placebo
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified July 2011 - Conditions: Smoking Cessation; Nicotine Dependence
Interventions: Drug: Nicotine Replacement Treatment (NRT); Drug: varenicline; Behavioral: Behavioral counseling for smoking cessation; Drug: Placebo patch; Drug: Placebo
Sponsors: Brown University; Brown University; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2009 - Condition: Alcoholism
Interventions: Drug: Prazosin medication; Drug: Placebo medication
Sponsors: Seattle Institute for Biomedical and Clinical Research; Seattle Institute for Biomedical and Clinical Research; National Institute on Alcohol Abuse and Alcoholism (NIAAA); VA Puget Sound Health Care System; University of Washington
Recruiting - verified April 2011 - Conditions: Alcohol Dependence; Stress Disorders, Post-Traumatic
Intervention: Drug: Prazosin
Sponsors: Yale University; Elizabeth Ralevski
Recruiting - verified January 2012 - Conditions: Alcohol Dependence; Dual Diagnosis; Drug Dependence
Intervention: Behavioral: In-Home-Messaging-Device (IHMDs)
Sponsors: Department of Veterans Affairs; Department of Veterans Affairs
Recruiting - verified March 2012 - Conditions: Attention Deficit Hyperactivity Disorder; Nicotine Dependence
Interventions: Drug: Lis-dexamphetamine (LDX; Vyvanse) and Transdermal Nicotine Patch; Drug: Placebo and transdermal nicotine patch
Sponsors: Duke University; Duke University; Shire Development LLC
Recruiting - verified June 2011 - Conditions: Alcohol Dependence; Anxiety Disorder
Intervention: Drug: disulfiram plus lorazepam
Sponsors: University of New Mexico; University of New Mexico; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified January 2012 - Conditions: Heroin Dependence; Opioid-Related Disorders; Cocaine Abuse or Dependence
Intervention:
Sponsors: Wayne State University; Wayne State University; National Institute on Drug Abuse (NIDA)
Recruiting - verified October 2011 - Condition: Cocaine Dependence
Interventions: Drug: Propranolol; Drug: Placebo
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2012 - Condition: Cocaine Dependence
Interventions: Drug: Ondansetron; Drug: Placebo
Sponsors: University of Virginia; University of Virginia; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Conditions: Heroin Dependence; Opioid-Related Disorders
Intervention:
Sponsors: Wayne State University; Wayne State University; National Institute on Drug Abuse (NIDA)
Recruiting - verified October 2011 - Condition: Nicotine Dependence
Interventions: Drug: varenicline; Device: transdermal nicotine patch
Sponsors: Medical University of South Carolina; Medical University of South Carolina
Recruiting - verified July 2010 - Condition: Smoking
Intervention: Other: Functional Magnetic Resonance Imaging (fMRI)
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center; National Institutes of Health (NIH)
Recruiting - verified December 2011 - Conditions: Alcohol Dependence; PTSD
Intervention: Other: modified CPT-C
Sponsors: Yale University; Elizabeth Ralevski
Recruiting - verified January 2012 - Condition: Cocaine Dependence
Interventions: Drug: Oral micronized progesterone; Drug: Placebo
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute on Drug Abuse (NIDA)
Recruiting - verified May 2012 - Condition: Cocaine Related Disorders
Intervention:
Sponsors: National Institute on Drug Abuse (NIDA); National Institute on Drug Abuse (NIDA)
Recruiting - verified September 2011 - Conditions: Opiate Dependence; Chronic Pain
Interventions: Behavioral: CBT; Drug: Buprenorphine; Other: Educational Counseling; Other: Physician Management
Sponsors: Yale University; Yale University
Recruiting - verified May 2012 - Condition: Opiate Dependence
Interventions: Behavioral: Behavioral: Buprenorphine/naloxone maintenance (Mtn); Behavioral: Behavioral: Buprenorphine/naloxone detoxification (Dtx)
Sponsors: Yale University; Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified November 2011 - Conditions: Adult Attention Deficit Hyperactivity Disorder; Cocaine Dependence
Interventions: Drug: Placebo; Drug: Adderall-XR; Drug: Adderall-XR
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2012 - Conditions: Nicotine Dependence; Psychotic Disorders
Interventions: Behavioral: Contingency Management; Behavioral: Reward
Sponsors: Department of Veterans Affairs; Department of Veterans Affairs
Recruiting - verified January 2012 - Conditions: Alcohol Dependence; Cocaine Dependence
Interventions: Drug: Topiramate + Cognitive Behavioral Therapy; Drug: Placebo + Cognitive Behavioral Therapy
Sponsors: University of Virginia; Bankole Johnson; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Condition: Cocaine-Related Disorders
Intervention: Procedure: acoustic startle testing
Sponsors: Emory University; Emory University; National Institute on Drug Abuse (NIDA)
Recruiting - verified March 2012 - Condition: Cocaine Dependence
Interventions: Drug: Modafinil; Drug: placebo; Behavioral: Cognitive Behavioral Therapy (CBT)
Sponsors: University of Pennsylvania; University of Pennsylvania
Recruiting - verified November 2011 - Condition: Alcoholism
Intervention: Drug: mecamylamine
Sponsors: Yale University; Elizabeth Ralevski
Recruiting - verified January 2012 - Conditions: Cocaine Abuse; Heroin Abuse
Interventions: Drug: Clonidine; Drug: Placebo
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified September 2011 - Conditions: Smoking; Tobacco Use Cessation
Interventions: Behavioral: MBAT Group Therapy; Drug: Nicotine; Behavioral: Group Therapy; Behavioral: Individual Therapy
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center; National Institute on Drug Abuse (NIDA)
Recruiting - verified May 2012 - Condition: Opioid-Related Disorders
Interventions: Drug: Clonidine; Drug: Placebo
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified March 2012 - Conditions: Stress Disorders, Post-Traumatic; Alcohol Abuse; Substance-Related Disorders
Interventions: Behavioral: Seeking Safety; Drug: Sertraline, "Zoloft" and Placebo
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified October 2011 - Conditions: Cocaine Dependence; Depression
Interventions: Drug: Mirtazapine; Drug: Placebo
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute on Drug Abuse (NIDA)
Recruiting - verified October 2011 - Conditions: Alcoholism; Alcohol Dependence; Alcohol Drinking Related Problems
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified October 2011 - Condition: Alcoholism
Interventions: Drug: ondansetron + cognitive behavioral therapy; Drug: topiramate + cognitive behavioral therapy; Drug: Placebo + cognitive behavioral therapy; Drug: ondansetron + topiramate + cognitive behavioral therapy
Sponsors: University of Virginia; Bankole Johnson; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified February 2012
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