- Condition: Glioblastoma
Interventions: Drug: Hydroxychloroquine; Radiation: Radiotherapy
Sponsors: University College, London; University College, London; Cancer Research UK
Not yet recruiting - verified May 2012 - Condition: Carpal Tunnel Syndrome
Intervention: Device: EMS Therasonic 460 Primo Ultrasound therapy
Sponsors: East Kent Hospitals University NHS Foundation Trust; East Kent Hospitals University NHS Foundation Trust
Not yet recruiting - verified May 2012 - Condition: Cardiovascular Function
Intervention: Biological: Typhoid vaccine
Sponsors: Queen Mary University of London; Queen Mary University of London
Recruiting - verified April 2012 - Condition: Rheumatoid Arthritis
Intervention:
Sponsors: Hoffmann-La Roche; Hoffmann-La Roche
Recruiting - verified April 2012 - Condition: Rheumatoid Arthritis
Interventions: Biological: MEDI5117; Biological: MEDI5117 Placebo
Sponsors: AstraZeneca; AstraZeneca
Recruiting - verified May 2012 - Conditions: Scleroderma, Systemic; Sclerosis, Systemic; Systemic Scleroderma; Systemic Sclerosis
Interventions: Drug: Pomalidomide (CC-4047); Drug: Placebo
Sponsors: Celgene Corporation; Celgene Corporation
Not yet recruiting - verified April 2012 - Condition: Rheumatoid Arthritis
Intervention:
Sponsors: Hoffmann-La Roche; Hoffmann-La Roche
Recruiting - verified May 2012 - Condition: Osteoarthritis
Intervention: Device: VANGUARD 360
Sponsors: Biomet, Inc.; Biomet, Inc.
Not yet recruiting - verified February 2012 - Condition: Toxicity From Medication (Endocrine Treatment and Chemotherapy) Given for Breast Cancer Treatment.
Intervention:
Sponsors: Imperial College London; Imperial College London
Recruiting - verified March 2012 - Conditions: Osteoarthritis; Post-traumatic Arthritis; Gout; Pseudo-gout
Intervention: Device: SIGMA HP PARTIAL KNEE
Sponsors: DePuy International; DePuy International
Recruiting - verified February 2012 - Condition: Osteoarthritis
Intervention:
Sponsors: University of Nottingham; University of Nottingham
Recruiting - verified April 2012 - Condition: Gout
Interventions: Other: Nurse intervention; Other: Standard care
Sponsors: University of Nottingham; University of Nottingham; Arthritis Research UK
Not yet recruiting - verified November 2011 - Conditions: Osteoarthritis; Avascular Necrosis; Rheumatoid Arthritis; Developmental Dysplasia of the Hip
Intervention:
Sponsors: Wirral University Teaching Hospital NHS Trust; Hussain Kazi
Not yet recruiting - verified September 2011 - Condition: Rheumatoid Arthritis
Interventions: Drug: Revamilast; Drug: Revamilast; Drug: Revamilast; Drug: Placebo Comparator
Sponsors: Glenmark Pharmaceuticals Ltd. India; Glenmark Pharmaceuticals Ltd. India; Glenmark Pharmaceuticals SA
Recruiting - verified December 2011 - Condition: Rheumatoid Arthritis
Interventions: Biological: Placebo to Secukinumab (AIN457); Biological: Secukinumab
Sponsors: Novartis; Novartis Pharmaceuticals
Recruiting - verified April 2012 - Condition: Acute Rheumatoid Arthritis
Intervention: Drug: s.c. injections of bovine intestinal Alkaline Phosphatase
Sponsors: Alloksys Life Sciences B.V.; Alloksys Life Sciences B.V.; Aix Scientifics
Recruiting - verified August 2011 - Condition: Osteoarthritis
Interventions: Device: Sigma CR150; Device: Sigma CR
Sponsors: DePuy International; DePuy International
Recruiting - verified February 2012 - Condition: Psoriatic Arthritis
Interventions: Biological: Secukinumab (75 mg); Biological: Secukinumab (150 mg); Biological: Placebo Comparator
Sponsors: Novartis; Novartis Pharmaceuticals
Recruiting - verified May 2012 - Conditions: Primary Arthritis; Secondary Arthritis
Intervention: Device: Silent™ Hip
Sponsors: DePuy International; DePuy International
Recruiting - verified February 2012 - Condition: Rheumatoid Arthritis
Intervention:
Sponsors: Abbott; Abbott
Recruiting - verified December 2011 - Condition: Rheumatoid Arthritis
Interventions: Drug: Secukinumab (75 mg); Drug: Secukinumab (150 mg); Drug: Placebo
Sponsors: Novartis; Novartis Pharmaceuticals
Recruiting - verified May 2012 - Condition: Ankylosing Spondylitis
Interventions: Biological: Secukinumab (75 mg); Biological: Secukinumab (150 mg); Biological: Placebo
Sponsors: Novartis; Novartis Pharmaceuticals
Recruiting - verified May 2012 - Condition: Revision Surgery of Total Hip Arthroplasty
Interventions: Drug: Denosumab; Other: Placebo
Sponsors: Sheffield Teaching Hospitals NHS Foundation Trust; Sheffield Teaching Hospitals NHS Foundation Trust; Amgen; NIHR Musculoskeletal BRU
Not yet recruiting - verified December 2011 - Condition: Cardiovascular Disease, Rheumatoid Arthritis
Interventions: Drug: tocilizumab [RoActemra/Actemra]; Drug: etanercept
Sponsors: Hoffmann-La Roche; Hoffmann-La Roche
Recruiting - verified March 2012 - Condition: Coxarthrosis
Intervention: Device: Primoris
Sponsors: Biomet, Inc.; Biomet, Inc.; Biomet Denmark A/S
Recruiting - verified May 2012 - Condition: Osteoarthritis of the Knee
Intervention: Other: Questionnaires
Sponsors: University of Nottingham; University of Nottingham; Arthritis Research Campaign
Recruiting - verified January 2012 - Condition: Rheumatoid Arthritis
Intervention: Biological: CDP6038
Sponsors: UCB, Inc.; UCB, Inc.
Recruiting - verified May 2012 - Condition: Rheumatoid Arthritis
Interventions: Drug: tocilizumab [RoActemra/Actemra]; Drug: adalimumab; Drug: Placebo; Drug: Placebo; Drug: methotrexate; Drug: folate
Sponsors: Hoffmann-La Roche; Hoffmann-La Roche
Recruiting - verified May 2012 - Condition: Rheumatoid Arthritis
Interventions: Drug: Fostamatinib and placebo injections; Drug: Fostamatinib and placebo injections; Drug: Fostamatinib and placebo injections; Drug: Adalimumab and placebo of fostamatinib; Drug: Placebo of fostamatinib, fostamatinib, and placebo injections
Sponsors: AstraZeneca; AstraZeneca
Recruiting - verified March 2012 - Condition: Spondylitis, Ankylosing
Interventions: Biological: etanercept; Drug: Background NSAID; Other: PLACEBO; Drug: Background NSAID
Sponsors: Pfizer; Pfizer
Recruiting - verified April 2012 - Condition: Rheumatoid Arthritis
Interventions: Drug: Fostamatinib; Drug: Fostamatinib; Drug: Fostamatinib
Sponsors: AstraZeneca; AstraZeneca
Recruiting - verified March 2012 - Condition: Chronic Periodontitis
Intervention:
Sponsors: NHS South Birmingham; NHS South Birmingham; University of Birmingham
Not yet recruiting - verified July 2010 - Condition: HIV Infection
Intervention: Drug: Hydroxychloroquine
Sponsors: St Stephens Aids Trust; St Stephens Aids Trust
Recruiting - verified December 2011 - Condition: Osteoarthritis of the Knee
Intervention: Device: Total Knee Arthroplasty
Sponsors: Smith & Nephew Orthopaedics AG; Smith & Nephew Orthopaedics AG
Recruiting - verified June 2011 - Condition: Arthritis, Rheumatoid
Interventions: Drug: Part 1: Etoricoxib 60 mg; Drug: Part 1: Etoricoxib 90 mg; Drug: Part 2: Etoricoxib 60 mg; Drug: Part 2: Etoricoxib 90 mg; Drug: Part 1: Placebo to Etoricoxib 60 mg; Drug: Part 1: Placebo to Etoricoxib 90 mg; Drug: Part 2: Placebo to Etoricoxib 60 mg; Drug: Part 2: Placebo to Etoricoxib 90 mg
Sponsors: Merck; Merck
Recruiting - verified May 2012 - Condition: Rheumatoid Arthritis
Interventions: Drug: fostamatinib; Drug: fostamatinib; Drug: placebo
Sponsors: AstraZeneca; AstraZeneca
Recruiting - verified March 2012 - Condition: Spondylitis, Ankylosing
Interventions: Drug: Part I - etoricoxib 60 mg; Drug: Part I - etoricoxib 90 mg; Drug: Part I- naproxen 1000 mg; Drug: Part I - Placebo to etoricoxib 60 mg; Drug: Part I - Placebo to etoricoxib 90 mg; Drug: Part I - Placebo to naproxen 500 mg; Drug: Part II- etoricoxib 60 mg; Drug: Part II- etoricoxib 90 mg; Drug: Part II- naproxen 1000 mg; Drug: Part II - Placebo to etoricoxib 60 mg; Drug: Part II - Placebo to etoricoxib 90 mg; Drug: Part II - Placebo to naproxen 500 mg
Sponsors: Merck; Merck
Recruiting - verified May 2012 - Condition: Psoriatic Arthritis
Intervention: Biological: AIN457A
Sponsors: Novartis; Novartis Pharmaceuticals
Recruiting - verified April 2012 - Condition: Myositis
Intervention: Procedure: Venepuncture
Sponsors: Salford Royal NHS Foundation Trust; Salford Royal NHS Foundation Trust
Recruiting - verified September 2011 - Conditions: Osteoarthritis; Rheumatoid Arthritis
Interventions: Procedure: Minimally Invasive Anterior Approach; Procedure: Standard postero-lateral approach
Sponsors: Medacta International SA; Medacta International SA
Recruiting - verified January 2012 - Conditions: Osteoarthritis; Arthritis; Avascular Necrosis; Fracture of the Femoral Neck or Head; Congenital Hip Dysplasia
Intervention: Device: AMIStem Hip System
Sponsors: Medacta International SA; Medacta International SA
Recruiting - verified January 2012 - Conditions: Rheumatoid Arthritis; Osteoarthritis; Post-traumatic Arthritis; Avascular Necrosis; Traumatic Femoral Fractures; Congenital Hip Dysplasia
Intervention: Device: DePuy Proxima™ Hip
Sponsors: DePuy International; DePuy International
Recruiting - verified February 2012 - Condition: Arthritis, Psoriatic
Interventions: Drug: placebo; Drug: ustekinumab; Drug: ustekinumab; Drug: placebo; Drug: placebo; Drug: ustekinumab; Drug: ustekinumab; Drug: ustekinumab
Sponsors: Centocor, Inc.; Centocor, Inc.
Recruiting - verified April 2012 - Condition: Arthritis, Rheumatoid
Interventions: Drug: Otelixizumab; Drug: Matching placebo
Sponsors: GlaxoSmithKline; GlaxoSmithKline
Recruiting - verified November 2011 - Conditions: Osteoarthritis; Rheumatoid Arthritis; Traumatic Arthritis
Interventions: Device: Vanguard CR; Device: AGC knee
Sponsors: Biomet, Inc.; Biomet, Inc.; Clinical Research and Trials Unit (Norfolk & Norwich University Hospital, UK); Biomet U.K. Ltd.
Recruiting - verified December 2011 - Conditions: Rheumatoid Arthritis; Ankylosing Spondylitis; Psoriatic Arthritis
Intervention: Drug: anti-TNF therapy (etanercept or adalimumab)
Sponsors: Imperial College London; Imperial College London
Recruiting - verified September 2011 - Condition: First MTP Joint Osteoarthritis
Interventions: Device: Arthrodesis; Device: Cartiva
Sponsors: Carticept Medical, Inc; Carticept Medical, Inc
Recruiting - verified August 2011 - Condition: HIV Infection
Intervention: Drug: All licensed antiretroviral medications
Sponsors: University of Minnesota - Clinical and Translational Science Institute; University of Minnesota - Clinical and Translational Science Institute; National Institute of Allergy and Infectious Diseases (NIAID); Copenhagen HIV Programme (CHIP) -- Copenhagen, Denmark; Medical Research Council (MRC) Clinical Trials Unit -- London, United Kingdom; Kirby Institute; The Institute for Clinical Research at the Veterans Affairs Medical Center -- Washington, D.C., USA; French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS); German Federal Ministry of Education and Research; NEAT - European AIDS Treatment Network; National Health and Medical Research Council, Australia; National Institutes of Health Clinical Center (CC); National Cancer Institute (NCI); National Heart, Lung, and Blood Institute (NHLBI); National Institute of Mental Health (NIMH); National Institute of Neurological Disorders and Stroke (NINDS); National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS); Abbott; Bristol-Myers Squibb; Gilead Sciences; GlaxoSmithKline; Merck; Tibotec Pharmaceutical Limited
Recruiting - verified April 2012 - Conditions: Osteoarthritis; Avascular Necrosis; Traumatic Arthritis; Rheumatoid Arthritis
Intervention: Procedure: metal on metal hip arthroplasty
Sponsors: Biomet, Inc.; Biomet, Inc.; Biomet U.K. Ltd.
Not yet recruiting - verified May 2012 - Conditions: Osteoarthritis; Rheumatoid Arthritis
Interventions: Drug: Celecoxib; Drug: non-selective Non steroidal anti inflammatory Drug
Sponsors: University of Dundee; University of Dundee; University of Glasgow; University of Nottingham
Recruiting - verified May 2012 - Condition: Arthritis, Rheumatoid
Interventions: Drug: CP-690,550; Drug: CP-690,550
Sponsors: Pfizer; Pfizer
Recruiting - verified May 2012 - Condition: Prostate Cancer
Interventions: Drug: celecoxib; Drug: docetaxel; Drug: prednisolone; Drug: releasing hormone agonist therapy; Drug: zoledronic acid; Drug: abiraterone; Procedure: orchiectomy
Sponsors: Medical Research Council; Medical Research Council
Recruiting - verified March 2012
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