- Condition: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: Drug: NVA237 50 µg and indacaterol 150 µg; Drug: Placebo to NVA237 and indacaterol 150 µg
Sponsors: Novartis; Novartis Pharmaceuticals
Not yet recruiting - verified May 2012 - Condition: COPD
Interventions: Device: Omnilab - AVAPS AE algorithm; Device: Usual care
Sponsors: Guy's and St Thomas' NHS Foundation Trust; Patrick Murphy; Philips Respironics
Recruiting - verified May 2012 - Conditions: Multiple Conditions; Coronary Heart Disease; Diabetes; Hypertension; Chronic Obstructive Pulmonary Disease
Intervention:
Sponsors: University of Southampton; University of Southampton
Not yet recruiting - verified May 2012 - Condition: Pulmonary Disease, Chronic Obstructive
Interventions: Drug: FF/VI; Other: Existing Maintenance Therapy
Sponsors: GlaxoSmithKline; GlaxoSmithKline
Recruiting - verified May 2012 - Condition: Chronic Obstructive Pulmonary Disease
Interventions: Drug: Losmapimod; Drug: Placebo
Sponsors: Cambridge University Hospitals NHS Foundation Trust; Cambridge University Hospitals NHS Foundation Trust; Technology Strategy Board; GlaxoSmithKline; Royal Brompton & Harefield NHS Foundation Trust; University of Cambridge
Not yet recruiting - verified February 2012 - Condition: Pulmonary Disease, Chronic Obstructive
Interventions: Drug: tiotropium+olodaterol; Drug: tiotropium + olodaterol (high dose); Drug: placebo to tiotropium+olodaterol
Sponsors: Boehringer Ingelheim Pharmaceuticals; Boehringer Ingelheim Pharmaceuticals
Recruiting - verified May 2012 - Conditions: Anxiety; COPD
Intervention: Drug: escitalopram
Sponsors: Hull and East Yorkshire Hospitals NHS Trust; Hull and East Yorkshire Hospitals NHS Trust
Not yet recruiting - verified January 2012 - Conditions: Pulmonary Disease, Chronic Obstructive; Respiratory Tract Diseases; Lung Diseases; Lung Diseases, Obstructive; Bronchitis, Chronic; Pulmonary Emphysema; Disease Progression
Intervention:
Sponsors: Royal Brompton & Harefield NHS Foundation Trust; Royal Brompton & Harefield NHS Foundation Trust; Medical Research Council; The Hillingdon Hospitals NHS Foundation Trust; West Hertfordshire Hospitals NHS Trust
Recruiting - verified January 2012 - Conditions: Pulmonary Disease, Chronic Obstructive; Lung Diseases, Obstructive; Pulmonary Emphysema; Bronchitis, Chronic; Lung Diseases; Disease Progression
Intervention:
Sponsors: Royal Brompton & Harefield NHS Foundation Trust; Royal Brompton & Harefield NHS Foundation Trust; Medical Research Council
Recruiting - verified January 2012 - Conditions: COPD; Chronic Obstructive Pulmonary Disease
Interventions: Drug: Roflumilast; Drug: Placebo
Sponsors: Nycomed; Nycomed
Recruiting - verified May 2012 - Condition: Pulmonary Disease, Chronic Obstructive
Interventions: Drug: Glycopyrrolate; Drug: Glycopyrrolate; Drug: Glycopyrrolate; Drug: Comparator
Sponsors: Chiesi Farmaceutici S.p.A.; Chiesi Farmaceutici S.p.A.
Not yet recruiting - verified November 2011 - Condition: Chronic Obstructive Pulmonary Disease
Interventions: Drug: Aclidinium Bromide; Drug: Placebo
Sponsors: Almirall, S.A.; Almirall, S.A.; Forest Laboratories
Recruiting - verified February 2012 - Condition: Chronic Obstructive Pulmonary Disease
Intervention:
Sponsors: Royal Brompton & Harefield NHS Foundation Trust; Royal Brompton & Harefield NHS Foundation Trust
Recruiting - verified December 2011 - Condition: Pulmonary Disease, Chronic Obstructive
Interventions: Drug: Aclidinium Bromide/Formoterol Fumarate; Drug: Aclidinium Bromide/Formoterol Fumarate; Drug: Aclidinium Bromide; Drug: Placebo; Drug: Formoterol Fumarate
Sponsors: Almirall, S.A.; Almirall, S.A.; Forest Laboratories
Recruiting - verified October 2011 - Condition: Chronic Obstructive Pulmonary Disease With (Acute) Exacerbation
Interventions: Drug: Roflumilast; Drug: Placebo
Sponsors: Nycomed; Nycomed
Recruiting - verified May 2012 - Condition: Chronic Obstructive Pulmonary Disease
Interventions: Biological: MEDI8968 SC for 12 months; Biological: Placebo SC for 12 months
Sponsors: MedImmune LLC; MedImmune LLC
Recruiting - verified May 2012 - Condition: Pulmonary Disease, Chronic Obstructive
Interventions: Drug: tiotropium + olodaterol; Drug: tiotropium; Drug: tiotropium; Drug: olodaterol
Sponsors: Boehringer Ingelheim Pharmaceuticals; Boehringer Ingelheim Pharmaceuticals
Recruiting - verified May 2012 - Condition: COPD Exacerbation
Intervention:
Sponsors: Hull and East Yorkshire Hospitals NHS Trust; Hull and East Yorkshire Hospitals NHS Trust; Philips Respironics
Recruiting - verified March 2012 - Condition: Chronic Obstructive Pulmonary Disease (COPD).
Interventions: Drug: Moxifloxacin; Drug: Azithromycin; Drug: Doxycycline; Drug: Placebo
Sponsors: University College, London; University College, London; Royal Free Hampstead NHS Trust; University of Cambridge; National Institute for Health Research, United Kingdom
Recruiting - verified June 2011 - Condition: Chronic Obstructive Pulmonary Disease (COPD)
Intervention:
Sponsors: Centre for Research in Environmental Epidemiology, Spain; Centre for Research in Environmental Epidemiology, Spain; Katholieke Universiteit Leuven; University of Edinburgh; Royal Brompton & Harefield NHS Foundation Trust; University Medical Centre Groningen; University of Athens
Recruiting - verified October 2011 - Condition: Chronic Obstructive Pulmonary Disease
Intervention:
Sponsors: Imperial College London; Imperial College London
Not yet recruiting - verified June 2011 - Conditions: Chronic Hypercapnic Respiratory Failure; Obesity Hypoventilation Syndrome; Neuromuscular Disease; Chronic Obstructive Pulmonary Disease
Intervention: Other: Surface parasternal electromyelography (EMG) set up
Sponsors: Guy's and St Thomas' NHS Foundation Trust; Guy's and St Thomas' NHS Foundation Trust; Royal Brompton & Harefield NHS Foundation Trust
Recruiting - verified January 2011 - Conditions: Chronic Obstructive Pulmonary Disease; Chronic Respiratory Hypercapnic Failure; Neuromuscular Disease; Obesity Hypoventilation Syndrome
Intervention: Device: non-invasive ventilation heated humidification (Fisher-Paykel MR810 and MR850 humidifiers)
Sponsors: Guy's and St Thomas' NHS Foundation Trust; Guy's and St Thomas' NHS Foundation Trust
Not yet recruiting - verified March 2011 - Conditions: Chronic Obstructive Pulmonary Disease; Acute Exacerbations of Chronic Obstructive Pulmonary Disease
Interventions: Procedure: Blood sample; Procedure: Sputum sample; Procedure: Nasopharyngeal swab; Procedure: Urine sample; Procedure: End tidal breath sample; Other: Data collection; Other: Tests
Sponsors: GlaxoSmithKline; GlaxoSmithKline
Recruiting - verified April 2012 - Condition: Chronic Obstructive Pulmonary Disease
Interventions: Drug: Roflumilast; Drug: Placebo
Sponsors: Nycomed; Nycomed
Recruiting - verified May 2012 - Condition: Chronic Obstructive Pulmonary Disease
Intervention: Drug: PUR118
Sponsors: Pulmatrix Inc.; Pulmatrix Inc.; Quotient Bioresearch
Recruiting - verified November 2011 - Condition: Pulmonary Disease, Chronic Obstructive
Interventions: Drug: PH-797804; Drug: Placebo
Sponsors: Pfizer; Pfizer
Recruiting - verified April 2012 - Conditions: COPD Method Evaluation; Chronic Obstructive Pulmonary Disease Method Evaluation
Interventions: Drug: Formoterol Turbuhaler; Drug: Budesonide/Formoterol Turbuhaler; Drug: Formoterol Turbuhaler
Sponsors: AstraZeneca; AstraZeneca
Recruiting - verified March 2012 - Condition: Pulmonary Disease, Chronic Obstructive
Interventions: Drug: Atimos®; Drug: Serevent™; Drug: Placebo
Sponsors: Chiesi Farmaceutici S.p.A.; Chiesi Farmaceutici S.p.A.
Recruiting - verified February 2012 - Conditions: Left Ventricular Systolic Dysfunction; Mitral Regurgitation
Intervention:
Sponsors: Imperial College London; Imperial College London; Humboldt-Universität zu Berlin; British Heart Foundation
Recruiting - verified August 2011 - Condition: Chronic Obstructive Pulmonary Disease
Interventions: Drug: Helium/Oxygen 78%/22%; Drug: Air/Oxygen
Sponsors: Air Liquide Santé International; Air Liquide Santé International
Recruiting - verified March 2012 - Condition: Chronic Obstructive Pulmonary Disease
Interventions: Drug: Simvastatin; Drug: Lactose tablet
Sponsors: University of Nottingham; University of Nottingham
Recruiting - verified January 2012 - Condition: Chronic Obstructive Pulmonary Disease
Interventions: Drug: Fosinopril; Other: lactose
Sponsors: Imperial College London; Imperial College London; Medical Research Council
Recruiting - verified June 2011 - Condition: Chronic Obstructive Pulmonary Disease
Interventions: Device: Non invasive ventilation; Device: LTOT
Sponsors: Guy's and St Thomas' NHS Foundation Trust; Patrick Murphy; Guy's & St Thomas' Charity; Respironics International; ResMed; ResMed Foundation
Recruiting - verified May 2012 - Condition: Pulmonary Disease, Chronic Obstructive
Interventions: Drug: Tiotropium +salmeterol+ fluticasone high dose; Drug: Tiotropium+salmeterol+ fluticasone high,med, low, placebo
Sponsors: Boehringer Ingelheim Pharmaceuticals; Boehringer Ingelheim Pharmaceuticals
Recruiting - verified May 2012
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